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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for AAGGUGC

Z-value: 0.33

Motif logo

miRNA associated with seed AAGGUGC

NamemiRBASE accession
MIMAT0000072
MIMAT0001412
MIMAT0019861

Activity profile of AAGGUGC motif

Sorted Z-values of AAGGUGC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_132272504 1.21 ENST00000367976.3
connective tissue growth factor
chr4_+_55524085 0.95 ENST00000412167.2
ENST00000288135.5
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr6_+_112408768 0.64 ENST00000368656.2
ENST00000604268.1
family with sequence similarity 229, member B
chr6_+_39760783 0.60 ENST00000398904.2
ENST00000538976.1
dishevelled associated activator of morphogenesis 2
chr12_+_104458235 0.53 ENST00000229330.4
host cell factor C2
chr15_-_61521495 0.50 ENST00000335670.6
RAR-related orphan receptor A
chr9_-_35563896 0.49 ENST00000399742.2
family with sequence similarity 166, member B
chr12_+_12764773 0.39 ENST00000228865.2
cAMP responsive element binding protein-like 2
chr9_-_74383799 0.35 ENST00000377044.4
transmembrane protein 2
chr11_-_108464321 0.33 ENST00000265843.4
exophilin 5
chr3_-_123603137 0.33 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
myosin light chain kinase
chr3_-_114790179 0.28 ENST00000462705.1
zinc finger and BTB domain containing 20
chr13_-_77601282 0.27 ENST00000355619.5
F-box and leucine-rich repeat protein 3
chr5_+_56111361 0.27 ENST00000399503.3
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chrX_+_150565653 0.25 ENST00000330374.6
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr16_+_69599861 0.25 ENST00000354436.2
nuclear factor of activated T-cells 5, tonicity-responsive
chr2_+_12857015 0.21 ENST00000155926.4
tribbles pseudokinase 2
chr5_-_73937244 0.20 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ectodermal-neural cortex 1 (with BTB domain)
chr1_+_87794150 0.20 ENST00000370544.5
LIM domain only 4
chr2_+_24714729 0.20 ENST00000406961.1
ENST00000405141.1
nuclear receptor coactivator 1
chr6_-_107436473 0.20 ENST00000369042.1
BEN domain containing 3
chr11_+_108093839 0.20 ENST00000452508.2
ataxia telangiectasia mutated
chr12_+_69864129 0.20 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
fibroblast growth factor receptor substrate 2
chr18_-_45456930 0.19 ENST00000262160.6
ENST00000587269.1
SMAD family member 2
chr17_-_27621125 0.17 ENST00000579665.1
ENST00000225388.4
nuclear fragile X mental retardation protein interacting protein 2
chr3_+_187930719 0.17 ENST00000312675.4
LIM domain containing preferred translocation partner in lipoma
chr11_-_130184555 0.16 ENST00000525842.1
zinc finger and BTB domain containing 44
chr9_+_96338860 0.16 ENST00000375376.4
PHD finger protein 2
chr1_+_38259540 0.15 ENST00000397631.3
mannosidase, endo-alpha-like
chr1_+_162467595 0.14 ENST00000538489.1
ENST00000489294.1
U2AF homology motif (UHM) kinase 1
chr2_-_26101374 0.14 ENST00000435504.4
additional sex combs like 2 (Drosophila)
chr2_+_36582857 0.14 ENST00000280527.2
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr20_+_49348081 0.14 ENST00000371610.2
par-6 family cell polarity regulator beta
chr16_+_28996114 0.14 ENST00000395461.3
linker for activation of T cells
chr5_-_180288248 0.14 ENST00000512132.1
ENST00000506439.1
ENST00000502412.1
ENST00000359141.6
ZFP62 zinc finger protein
chr7_+_90225796 0.13 ENST00000380050.3
cyclin-dependent kinase 14
chr17_+_68165657 0.13 ENST00000243457.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr3_+_105085734 0.13 ENST00000306107.5
activated leukocyte cell adhesion molecule
chr16_+_71879861 0.13 ENST00000427980.2
ENST00000568581.1
ataxin 1-like
increased sodium tolerance 1 homolog (yeast)
chr10_+_133918175 0.13 ENST00000298622.4
Janus kinase and microtubule interacting protein 3
chr6_+_122720681 0.13 ENST00000368455.4
ENST00000452194.1
heat shock transcription factor 2
chr12_-_56652111 0.13 ENST00000267116.7
ankyrin repeat domain 52
chr11_-_72853091 0.12 ENST00000311172.7
ENST00000409314.1
FCH and double SH3 domains 2
chr6_-_86352642 0.12 ENST00000355238.6
synaptotagmin binding, cytoplasmic RNA interacting protein
chr10_+_111767720 0.11 ENST00000356080.4
ENST00000277900.8
adducin 3 (gamma)
chrX_-_24045303 0.10 ENST00000328046.8
kelch-like family member 15
chr1_-_204329013 0.10 ENST00000272203.3
ENST00000414478.1
pleckstrin homology domain containing, family A member 6
chr17_+_40834580 0.10 ENST00000264638.4
contactin associated protein 1
chr12_+_11802753 0.10 ENST00000396373.4
ets variant 6
chr16_-_57219966 0.10 ENST00000565760.1
ENST00000309137.8
ENST00000570184.1
ENST00000562324.1
family with sequence similarity 192, member A
chr9_+_108424738 0.10 ENST00000334077.3
T-cell acute lymphocytic leukemia 2
chr7_-_100287071 0.10 ENST00000275732.5
GRB10 interacting GYF protein 1
chr7_+_66386204 0.10 ENST00000341567.4
ENST00000607045.1
transmembrane protein 248
chr1_-_70820357 0.10 ENST00000370944.4
ENST00000262346.6
ankyrin repeat domain 13C
chr15_+_76629064 0.10 ENST00000290759.4
ISL LIM homeobox 2
chr1_+_26737253 0.10 ENST00000326279.6
lin-28 homolog A (C. elegans)
chr2_+_46926048 0.09 ENST00000306503.5
suppressor of cytokine signaling 5
chr22_+_40573921 0.09 ENST00000454349.2
ENST00000335727.9
trinucleotide repeat containing 6B
chr12_+_54943134 0.09 ENST00000243052.3
phosphodiesterase 1B, calmodulin-dependent
chr17_-_7382834 0.09 ENST00000380599.4
zinc finger and BTB domain containing 4
chr21_-_36260980 0.08 ENST00000344691.4
ENST00000358356.5
runt-related transcription factor 1
chr21_-_40685477 0.08 ENST00000342449.3
bromodomain and WD repeat domain containing 1
chr1_-_51425902 0.08 ENST00000396153.2
Fas (TNFRSF6) associated factor 1
chr3_+_152017181 0.08 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
muscleblind-like splicing regulator 1
chr9_-_99180597 0.07 ENST00000375256.4
zinc finger protein 367
chr9_-_93405352 0.07 ENST00000375765.3
DIRAS family, GTP-binding RAS-like 2
chr6_+_138188551 0.07 ENST00000237289.4
ENST00000433680.1
tumor necrosis factor, alpha-induced protein 3
chr20_+_60697480 0.07 ENST00000370915.1
ENST00000253001.4
ENST00000400318.2
ENST00000279068.6
ENST00000279069.7
LSM14B, SCD6 homolog B (S. cerevisiae)
chr16_+_77822427 0.07 ENST00000302536.2
vesicle amine transport 1-like
chr4_+_154125565 0.07 ENST00000338700.5
tripartite motif containing 2
chr1_-_55680762 0.07 ENST00000407756.1
ENST00000294383.6
ubiquitin specific peptidase 24
chr20_+_30865429 0.06 ENST00000375712.3
kinesin family member 3B
chr4_+_6784401 0.06 ENST00000425103.1
ENST00000307659.5
KIAA0232
chr5_-_139422654 0.06 ENST00000289409.4
ENST00000358522.3
ENST00000378238.4
ENST00000289422.7
ENST00000361474.1
ENST00000545385.1
ENST00000394770.1
ENST00000541337.1
neuregulin 2
chr6_-_37665751 0.06 ENST00000297153.7
ENST00000434837.3
MAM domain containing glycosylphosphatidylinositol anchor 1
chr20_+_43104508 0.06 ENST00000262605.4
ENST00000372904.3
tocopherol (alpha) transfer protein-like
chrX_-_19905703 0.06 ENST00000397821.3
SH3-domain kinase binding protein 1
chr4_-_125633876 0.05 ENST00000504087.1
ENST00000515641.1
ankyrin repeat domain 50
chr1_-_110052302 0.05 ENST00000369864.4
ENST00000369862.1
adhesion molecule with Ig-like domain 1
chr17_+_27717415 0.05 ENST00000583121.1
ENST00000261716.3
TAO kinase 1
chr18_-_29522989 0.05 ENST00000582539.1
ENST00000283351.4
ENST00000582513.1
trafficking protein particle complex 8
chr21_-_18985158 0.05 ENST00000339775.6
BTG family, member 3
chr4_-_42659102 0.05 ENST00000264449.10
ENST00000510289.1
ENST00000381668.5
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr12_+_94542459 0.04 ENST00000258526.4
plexin C1
chr10_+_72575643 0.04 ENST00000373202.3
sphingosine-1-phosphate lyase 1
chr10_+_102295616 0.04 ENST00000299163.6
hypoxia inducible factor 1, alpha subunit inhibitor
chr7_-_121036337 0.04 ENST00000426156.1
ENST00000359943.3
ENST00000412653.1
family with sequence similarity 3, member C
chr4_+_79697495 0.04 ENST00000502871.1
ENST00000335016.5
BMP2 inducible kinase
chr8_+_28747884 0.04 ENST00000287701.10
ENST00000444075.1
ENST00000403668.2
ENST00000519662.1
ENST00000558662.1
ENST00000523613.1
ENST00000560599.1
ENST00000397358.3
homeobox containing 1
chr15_+_73344791 0.04 ENST00000261908.6
neogenin 1
chr11_-_79151695 0.03 ENST00000278550.7
teneurin transmembrane protein 4
chr9_+_125703282 0.03 ENST00000373647.4
ENST00000402311.1
RAB GTPase activating protein 1
chr1_-_228135599 0.03 ENST00000272164.5
wingless-type MMTV integration site family, member 9A
chr2_+_85198216 0.03 ENST00000456682.1
ENST00000409785.4
potassium channel modulatory factor 1
chr3_+_37903432 0.03 ENST00000443503.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr9_+_91003271 0.03 ENST00000375859.3
ENST00000541629.1
spindlin 1
chr12_+_5019061 0.03 ENST00000382545.3
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr5_+_125935960 0.03 ENST00000297540.4
phosphorylated adaptor for RNA export
chr3_-_169899504 0.03 ENST00000474275.1
ENST00000484931.1
ENST00000494943.1
ENST00000497658.1
ENST00000465896.1
ENST00000475729.1
ENST00000495893.2
ENST00000481639.1
ENST00000467570.1
ENST00000466189.1
polyhomeotic homolog 3 (Drosophila)
chr3_-_33481835 0.03 ENST00000283629.3
upstream binding protein 1 (LBP-1a)
chr2_-_201828356 0.03 ENST00000234296.2
origin recognition complex, subunit 2
chr1_+_62208091 0.03 ENST00000316485.6
ENST00000371158.2
InaD-like (Drosophila)
chr8_-_145701718 0.03 ENST00000377317.4
forkhead box H1
chr1_+_167190066 0.03 ENST00000367866.2
ENST00000429375.2
ENST00000452019.1
ENST00000420254.3
ENST00000541643.3
POU class 2 homeobox 1
chr11_+_109964087 0.02 ENST00000278590.3
zinc finger CCCH-type containing 12C
chr5_+_122424816 0.02 ENST00000407847.4
PR domain containing 6
chr6_+_134274322 0.02 ENST00000367871.1
ENST00000237264.4
TBP-like 1
chr1_-_109506036 0.02 ENST00000369976.1
ENST00000356970.2
ENST00000369971.2
ENST00000415331.1
ENST00000357393.4
chloride channel CLIC-like 1
AKNA domain containing 1
chr2_-_206950781 0.02 ENST00000403263.1
INO80 complex subunit D
chr20_+_277737 0.02 ENST00000382352.3
zinc finger, CCHC domain containing 3
chr10_-_71930222 0.02 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1 homolog A (S. cerevisiae)
chr1_-_57889687 0.01 ENST00000371236.2
ENST00000371230.1
Dab, reelin signal transducer, homolog 1 (Drosophila)
chr3_+_141205852 0.01 ENST00000286364.3
ENST00000452898.1
RAS p21 protein activator 2
chr10_-_81205373 0.01 ENST00000372336.3
zinc finger, CCHC domain containing 24
chrX_+_108780062 0.01 ENST00000372106.1
nuclear transport factor 2-like export factor 2
chr5_-_59189545 0.01 ENST00000340635.6
phosphodiesterase 4D, cAMP-specific
chr9_-_127952032 0.01 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
protein phosphatase 6, catalytic subunit
chr5_+_96271141 0.01 ENST00000231368.5
leucyl/cystinyl aminopeptidase
chr12_-_56583332 0.01 ENST00000347471.4
ENST00000267064.4
ENST00000394023.3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr3_+_43328004 0.01 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNF related kinase
chr20_+_43595115 0.01 ENST00000372806.3
ENST00000396731.4
ENST00000372801.1
ENST00000499879.2
serine/threonine kinase 4
chr1_+_22379120 0.01 ENST00000400259.1
ENST00000344548.3
cell division cycle 42
chr18_+_20513782 0.01 ENST00000399722.2
ENST00000399725.2
ENST00000399721.2
ENST00000583594.1
retinoblastoma binding protein 8
chr10_-_119806085 0.01 ENST00000355624.3
RAB11 family interacting protein 2 (class I)
chr3_+_42695176 0.01 ENST00000232974.6
ENST00000457842.3
zinc finger and BTB domain containing 47
chr6_+_16238786 0.00 ENST00000259727.4
guanosine monophosphate reductase
chr7_-_44924939 0.00 ENST00000395699.2
purine-rich element binding protein B
chr16_-_85722530 0.00 ENST00000253462.3
GINS complex subunit 2 (Psf2 homolog)

Network of associatons between targets according to the STRING database.

First level regulatory network of AAGGUGC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0034059 response to anoxia(GO:0034059)
0.3 0.9 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.2 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.2 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.2 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.5 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0071947 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) negative regulation of osteoclast proliferation(GO:0090291)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.0 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0032289 central nervous system myelin formation(GO:0032289)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 1.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 1.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway