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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for AAUGCCC
Z-value: 0.40
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miRNA associated with seed AAUGCCC
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_-_149365827 Show fit | 2.92 |
ENST00000344721.4
|
nuclear receptor subfamily 3, group C, member 2 |
|
| chr1_-_46598284 Show fit | 1.70 |
ENST00000423209.1
ENST00000262741.5 |
phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
|
| chr17_+_68165657 Show fit | 1.26 |
ENST00000243457.3
|
potassium inwardly-rectifying channel, subfamily J, member 2 |
|
| chr6_-_134639180 Show fit | 0.99 |
ENST00000367858.5
|
serum/glucocorticoid regulated kinase 1 |
|
| chr1_+_61547894 Show fit | 0.82 |
ENST00000403491.3
|
nuclear factor I/A |
|
| chr3_+_23986748 Show fit | 0.79 |
ENST00000312521.4
|
nuclear receptor subfamily 1, group D, member 2 |
|
| chr17_+_55333876 Show fit | 0.75 |
ENST00000284073.2
|
musashi RNA-binding protein 2 |
|
| chr11_+_2466218 Show fit | 0.68 |
ENST00000155840.5
|
potassium voltage-gated channel, KQT-like subfamily, member 1 |
|
| chr20_-_39317868 Show fit | 0.64 |
ENST00000373313.2
|
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
|
| chr5_-_100238956 Show fit | 0.58 |
ENST00000231461.5
|
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of AAUGCCC
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | GO:0060453 | regulation of gastric acid secretion(GO:0060453) |
| 0.1 | 1.7 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
| 0.4 | 1.3 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
| 0.0 | 0.8 | GO:0072189 | ureter development(GO:0072189) |
| 0.0 | 0.8 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
| 0.2 | 0.6 | GO:0021571 | rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
| 0.0 | 0.6 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.2 | 0.5 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.1 | 0.5 | GO:0032803 | regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) |
| 0.1 | 0.4 | GO:0021986 | epithalamus development(GO:0021538) habenula development(GO:0021986) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.6 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 1.3 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 0.6 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 0.5 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.4 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.0 | 0.4 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 0.4 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.1 | 0.3 | GO:0035339 | SPOTS complex(GO:0035339) |
| 0.1 | 0.3 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.0 | 0.3 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.4 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.1 | 1.7 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.1 | 1.4 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
| 0.0 | 1.0 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.1 | 0.8 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 0.8 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 0.7 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
| 0.1 | 0.6 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.0 | 0.5 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.5 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 0.9 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 0.9 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.2 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 1.7 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 1.2 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.8 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.4 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.4 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.3 | REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION | Genes involved in RORA Activates Circadian Expression |
| 0.0 | 0.1 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |