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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for AGUGCUU

Z-value: 0.65

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miRNA associated with seed AGUGCUU

NamemiRBASE accession
hsa-miR-302c-3p.2
hsa-miR-520f-3p
MIMAT0002830

Activity profile of AGUGCUU motif

Sorted Z-values of AGUGCUU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_4382917 3.03 ENST00000261254.3
CCND2
cyclin D2
chr2_-_72375167 2.88 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr17_+_70117153 2.31 ENST00000245479.2
SOX9
SRY (sex determining region Y)-box 9
chr2_-_208030647 2.19 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr20_+_3776371 2.12 ENST00000245960.5
CDC25B
cell division cycle 25B
chr1_-_20812690 2.01 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr2_+_174219548 1.75 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
CDCA7
cell division cycle associated 7
chr7_-_41742697 1.54 ENST00000242208.4
INHBA
inhibin, beta A
chr21_-_44846999 1.46 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr2_-_235405679 1.46 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr3_+_47324424 1.36 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18
kelch-like family member 18
chr4_-_111119804 1.32 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr12_+_56915713 1.20 ENST00000262031.5
ENST00000552247.2
RBMS2
RNA binding motif, single stranded interacting protein 2
chr14_-_35182994 1.14 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr15_-_91537723 1.09 ENST00000394249.3
ENST00000559811.1
ENST00000442656.2
ENST00000557905.1
ENST00000361919.3
PRC1
protein regulator of cytokinesis 1
chr1_+_178694300 1.08 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr9_-_99180597 1.02 ENST00000375256.4
ZNF367
zinc finger protein 367
chr9_+_137218362 1.02 ENST00000481739.1
RXRA
retinoid X receptor, alpha
chr2_+_110371905 1.01 ENST00000356454.3
SOWAHC
sosondowah ankyrin repeat domain family member C
chr18_+_21269404 1.01 ENST00000313654.9
LAMA3
laminin, alpha 3
chr1_+_203595903 0.97 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr17_+_4736627 0.92 ENST00000355280.6
ENST00000347992.7
MINK1
misshapen-like kinase 1
chr11_-_102962929 0.88 ENST00000260247.5
DCUN1D5
DCN1, defective in cullin neddylation 1, domain containing 5
chr11_-_119599794 0.87 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr3_-_87040233 0.86 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr1_-_244013384 0.85 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr7_-_28220354 0.80 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr17_+_26662730 0.80 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr15_+_69706585 0.80 ENST00000559279.1
ENST00000395392.2
KIF23
kinesin family member 23
chr12_-_108154925 0.79 ENST00000228437.5
PRDM4
PR domain containing 4
chr8_+_42752053 0.75 ENST00000307602.4
HOOK3
hook microtubule-tethering protein 3
chr2_-_43453734 0.75 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr3_-_45017609 0.75 ENST00000342790.4
ENST00000424952.2
ENST00000296127.3
ENST00000455235.1
ZDHHC3
zinc finger, DHHC-type containing 3
chr3_-_149093499 0.74 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr17_-_17875688 0.74 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2
target of myb1-like 2 (chicken)
chr8_-_105601134 0.73 ENST00000276654.5
ENST00000424843.2
LRP12
low density lipoprotein receptor-related protein 12
chr22_+_38302285 0.73 ENST00000215957.6
MICALL1
MICAL-like 1
chr2_+_173940442 0.73 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr9_-_35732362 0.72 ENST00000314888.9
ENST00000540444.1
TLN1
talin 1
chr15_+_38544476 0.71 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr16_-_85722530 0.70 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr22_-_22221900 0.69 ENST00000215832.6
ENST00000398822.3
MAPK1
mitogen-activated protein kinase 1
chr9_-_95432536 0.69 ENST00000287996.3
IPPK
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr1_+_178062855 0.65 ENST00000448150.3
RASAL2
RAS protein activator like 2
chr3_-_48229846 0.65 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A
cell division cycle 25A
chr17_-_79919154 0.64 ENST00000409678.3
NOTUM
notum pectinacetylesterase homolog (Drosophila)
chr9_+_2621798 0.63 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr1_-_53793584 0.62 ENST00000354412.3
ENST00000347547.2
ENST00000306052.6
LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr11_+_119076745 0.62 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr6_-_42419649 0.61 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1
transcriptional regulating factor 1
chr1_+_214776516 0.60 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr11_-_78052923 0.60 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr3_+_14860469 0.60 ENST00000285046.5
FGD5
FYVE, RhoGEF and PH domain containing 5
chr20_+_1875110 0.59 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chr11_+_69455855 0.58 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chrX_+_41192595 0.58 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr15_-_73661605 0.58 ENST00000261917.3
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr1_-_230561475 0.57 ENST00000391860.1
PGBD5
piggyBac transposable element derived 5
chr4_+_156588350 0.57 ENST00000296518.7
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr10_+_98741041 0.56 ENST00000286067.2
C10orf12
chromosome 10 open reading frame 12
chr6_-_108395907 0.56 ENST00000193322.3
OSTM1
osteopetrosis associated transmembrane protein 1
chr9_+_128509624 0.56 ENST00000342287.5
ENST00000373487.4
PBX3
pre-B-cell leukemia homeobox 3
chr6_+_41040678 0.55 ENST00000341376.6
ENST00000353205.5
NFYA
nuclear transcription factor Y, alpha
chr7_+_28452130 0.54 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr1_-_38325256 0.54 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr3_-_197476560 0.53 ENST00000273582.5
KIAA0226
KIAA0226
chr1_+_25071848 0.53 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr11_-_85780086 0.52 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr6_+_158244223 0.51 ENST00000392185.3
SNX9
sorting nexin 9
chr3_-_69435224 0.51 ENST00000398540.3
FRMD4B
FERM domain containing 4B
chr8_+_102504651 0.51 ENST00000251808.3
ENST00000521085.1
GRHL2
grainyhead-like 2 (Drosophila)
chr1_-_85156216 0.50 ENST00000342203.3
ENST00000370612.4
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr2_+_26256938 0.50 ENST00000264710.4
RAB10
RAB10, member RAS oncogene family
chr7_+_138916231 0.49 ENST00000473989.3
ENST00000288561.8
UBN2
ubinuclein 2
chr2_+_26568965 0.48 ENST00000260585.7
ENST00000447170.1
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr17_-_76356148 0.48 ENST00000587578.1
ENST00000330871.2
SOCS3
suppressor of cytokine signaling 3
chrX_-_46618490 0.48 ENST00000328306.4
SLC9A7
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
chr2_+_118846008 0.48 ENST00000245787.4
INSIG2
insulin induced gene 2
chr10_+_43633914 0.47 ENST00000374466.3
ENST00000374464.1
CSGALNACT2
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr3_-_164913777 0.47 ENST00000475390.1
SLITRK3
SLIT and NTRK-like family, member 3
chr20_+_56884752 0.46 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr9_-_110251836 0.46 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr4_-_41216619 0.46 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr13_-_79177673 0.45 ENST00000377208.5
POU4F1
POU class 4 homeobox 1
chr3_-_122233723 0.44 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1
karyopherin alpha 1 (importin alpha 5)
chrX_+_28605516 0.44 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr13_+_52158610 0.42 ENST00000298125.5
WDFY2
WD repeat and FYVE domain containing 2
chr13_-_25746416 0.42 ENST00000515384.1
ENST00000357816.2
AMER2
APC membrane recruitment protein 2
chr19_-_2050852 0.42 ENST00000541165.1
ENST00000591601.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr8_-_60031762 0.41 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr17_+_38333263 0.40 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr5_-_141704566 0.39 ENST00000344120.4
ENST00000434127.2
SPRY4
sprouty homolog 4 (Drosophila)
chr11_+_122526383 0.39 ENST00000284273.5
UBASH3B
ubiquitin associated and SH3 domain containing B
chr22_-_36236265 0.39 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr17_-_5138099 0.38 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chrX_+_16737718 0.37 ENST00000380155.3
SYAP1
synapse associated protein 1
chr3_+_126707437 0.37 ENST00000393409.2
ENST00000251772.4
PLXNA1
plexin A1
chr12_-_54779511 0.36 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr8_-_124408652 0.36 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr5_+_176560742 0.34 ENST00000439151.2
NSD1
nuclear receptor binding SET domain protein 1
chr12_+_32655048 0.34 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr2_+_11674213 0.34 ENST00000381486.2
GREB1
growth regulation by estrogen in breast cancer 1
chr11_+_64126614 0.34 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
RPS6KA4
ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr5_-_171433819 0.34 ENST00000296933.6
FBXW11
F-box and WD repeat domain containing 11
chrX_+_24072833 0.34 ENST00000253039.4
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr1_+_78245303 0.33 ENST00000370791.3
ENST00000443751.2
FAM73A
family with sequence similarity 73, member A
chr4_-_114900831 0.33 ENST00000315366.7
ARSJ
arylsulfatase family, member J
chr3_+_23244780 0.33 ENST00000396703.1
UBE2E2
ubiquitin-conjugating enzyme E2E 2
chr1_-_70671216 0.32 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr10_-_23003460 0.32 ENST00000376573.4
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr10_+_94050913 0.32 ENST00000358935.2
MARCH5
membrane-associated ring finger (C3HC4) 5
chr8_+_58907104 0.32 ENST00000361488.3
FAM110B
family with sequence similarity 110, member B
chr9_-_107690420 0.31 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr18_-_51751132 0.31 ENST00000256429.3
MBD2
methyl-CpG binding domain protein 2
chr2_+_9346892 0.31 ENST00000281419.3
ENST00000315273.4
ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chrX_-_70288234 0.31 ENST00000276105.3
ENST00000374274.3
SNX12
sorting nexin 12
chr6_+_45389893 0.31 ENST00000371432.3
RUNX2
runt-related transcription factor 2
chr17_+_5185552 0.30 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
RABEP1
rabaptin, RAB GTPase binding effector protein 1
chr3_-_183735731 0.30 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr2_+_185463093 0.30 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr1_+_7831323 0.30 ENST00000054666.6
VAMP3
vesicle-associated membrane protein 3
chr12_+_20522179 0.30 ENST00000359062.3
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr3_+_14989076 0.30 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr5_-_44388899 0.29 ENST00000264664.4
FGF10
fibroblast growth factor 10
chr1_+_12040238 0.29 ENST00000444836.1
ENST00000235329.5
MFN2
mitofusin 2
chr12_-_76953284 0.29 ENST00000547544.1
ENST00000393249.2
OSBPL8
oxysterol binding protein-like 8
chr19_+_39138271 0.28 ENST00000252699.2
ACTN4
actinin, alpha 4
chr12_-_96184533 0.28 ENST00000343702.4
ENST00000344911.4
NTN4
netrin 4
chr8_+_106330920 0.28 ENST00000407775.2
ZFPM2
zinc finger protein, FOG family member 2
chr5_+_170814803 0.27 ENST00000521672.1
ENST00000351986.6
ENST00000393820.2
ENST00000523622.1
NPM1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr9_+_116638562 0.27 ENST00000374126.5
ENST00000288466.7
ZNF618
zinc finger protein 618
chr11_+_128563652 0.27 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr1_+_200708671 0.27 ENST00000358823.2
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr10_-_75910789 0.27 ENST00000355264.4
AP3M1
adaptor-related protein complex 3, mu 1 subunit
chr12_+_88536067 0.27 ENST00000549011.1
ENST00000266712.6
ENST00000551088.1
TMTC3
transmembrane and tetratricopeptide repeat containing 3
chr2_+_103236004 0.26 ENST00000233969.2
SLC9A2
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr16_+_24741013 0.26 ENST00000315183.7
ENST00000395799.3
TNRC6A
trinucleotide repeat containing 6A
chr14_-_47812321 0.26 ENST00000357362.3
ENST00000486952.2
ENST00000426342.1
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr20_+_46130601 0.26 ENST00000341724.6
NCOA3
nuclear receptor coactivator 3
chr8_-_141645645 0.26 ENST00000519980.1
ENST00000220592.5
AGO2
argonaute RISC catalytic component 2
chr3_-_56835967 0.25 ENST00000495373.1
ENST00000296315.3
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr3_+_37493610 0.25 ENST00000264741.5
ITGA9
integrin, alpha 9
chr11_+_32914579 0.25 ENST00000399302.2
QSER1
glutamine and serine rich 1
chr14_+_67826709 0.24 ENST00000256383.4
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr17_+_40761660 0.24 ENST00000251413.3
ENST00000591509.1
TUBG1
tubulin, gamma 1
chrX_-_30885319 0.24 ENST00000378933.1
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr10_-_120514720 0.24 ENST00000369151.3
ENST00000340214.4
CACUL1
CDK2-associated, cullin domain 1
chr3_-_176914238 0.23 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr15_+_66161871 0.23 ENST00000569896.1
RAB11A
RAB11A, member RAS oncogene family
chr7_+_100136811 0.23 ENST00000300176.4
ENST00000262935.4
AGFG2
ArfGAP with FG repeats 2
chr6_+_152011628 0.23 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr3_+_132136331 0.22 ENST00000260818.6
DNAJC13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr2_+_178257372 0.22 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr1_-_150552006 0.22 ENST00000307940.3
ENST00000369026.2
MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
chr17_+_38375574 0.22 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2
WAS/WASL interacting protein family, member 2
chr6_+_35310312 0.22 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD
peroxisome proliferator-activated receptor delta
chr2_-_183903133 0.21 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr4_+_99916765 0.21 ENST00000296411.6
METAP1
methionyl aminopeptidase 1
chr2_+_99953816 0.21 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chr14_+_50359773 0.20 ENST00000298316.5
ARF6
ADP-ribosylation factor 6
chr3_-_179754706 0.20 ENST00000465751.1
ENST00000467460.1
PEX5L
peroxisomal biogenesis factor 5-like
chrX_+_24483338 0.20 ENST00000379162.4
ENST00000441463.2
PDK3
pyruvate dehydrogenase kinase, isozyme 3
chr1_+_2985760 0.19 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
PRDM16
PR domain containing 16
chr2_-_11484710 0.19 ENST00000315872.6
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr18_-_18691739 0.18 ENST00000399799.2
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chr7_+_129074266 0.18 ENST00000249344.2
ENST00000435494.2
STRIP2
striatin interacting protein 2
chr1_-_102462565 0.18 ENST00000370103.4
OLFM3
olfactomedin 3
chr7_-_123389104 0.18 ENST00000223023.4
WASL
Wiskott-Aldrich syndrome-like
chr20_-_41818373 0.18 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT
protein tyrosine phosphatase, receptor type, T
chr14_-_23504087 0.17 ENST00000493471.2
ENST00000460922.2
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr2_+_7057523 0.17 ENST00000320892.6
RNF144A
ring finger protein 144A
chr3_-_24536253 0.17 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB
thyroid hormone receptor, beta
chr16_+_25703274 0.17 ENST00000331351.5
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr1_+_184356188 0.17 ENST00000235307.6
C1orf21
chromosome 1 open reading frame 21
chr3_+_119013185 0.17 ENST00000264245.4
ARHGAP31
Rho GTPase activating protein 31
chr6_+_24667257 0.16 ENST00000537591.1
ENST00000230048.4
ACOT13
acyl-CoA thioesterase 13
chr16_+_7382745 0.16 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr12_+_56137064 0.16 ENST00000257868.5
ENST00000546799.1
GDF11
growth differentiation factor 11
chr9_-_111929560 0.16 ENST00000561981.2
FRRS1L
ferric-chelate reductase 1-like
chr4_+_74606223 0.16 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr2_-_85788605 0.16 ENST00000233838.4
GGCX
gamma-glutamyl carboxylase
chr10_+_112631547 0.16 ENST00000280154.7
ENST00000393104.2
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr1_+_97187318 0.15 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chr19_+_33463127 0.15 ENST00000589646.1
ENST00000588258.1
ENST00000590179.1
C19orf40
chromosome 19 open reading frame 40
chr17_-_62658186 0.15 ENST00000262435.9
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chrX_+_110339439 0.15 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr3_+_30648066 0.15 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr11_-_110167352 0.15 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX
radixin
chr8_-_119634141 0.14 ENST00000409003.4
ENST00000526328.1
ENST00000314727.4
ENST00000526765.1
SAMD12
sterile alpha motif domain containing 12
chr4_-_102268628 0.14 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr11_-_132813566 0.14 ENST00000331898.7
OPCML
opioid binding protein/cell adhesion molecule-like
chr22_+_29469012 0.14 ENST00000400335.4
ENST00000400338.2
KREMEN1
kringle containing transmembrane protein 1
chr12_+_111471828 0.14 ENST00000261726.6
CUX2
cut-like homeobox 2
chr12_-_31744031 0.14 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr7_+_97910981 0.14 ENST00000297290.3
BRI3
brain protein I3
chr6_-_71666732 0.14 ENST00000230053.6
B3GAT2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr1_+_117602925 0.14 ENST00000369466.4
TTF2
transcription termination factor, RNA polymerase II
chr1_-_21377447 0.14 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr3_+_152017181 0.14 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1
muscleblind-like splicing regulator 1
chrX_-_71933888 0.14 ENST00000373542.4
ENST00000339490.3
ENST00000541944.1
ENST00000373539.3
ENST00000373545.3
PHKA1
phosphorylase kinase, alpha 1 (muscle)

Network of associatons between targets according to the STRING database.

First level regulatory network of AGUGCUU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:1902811 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.8 2.3 GO:0072034 primary prostatic bud elongation(GO:0060516) renal vesicle induction(GO:0072034)
0.5 1.5 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 1.0 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.3 1.0 GO:2000283 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.3 1.5 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.3 1.1 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.2 0.7 GO:0019858 cytosine metabolic process(GO:0019858)
0.2 0.2 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.2 0.8 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 2.1 GO:0007144 female meiosis I(GO:0007144)
0.2 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.2 0.5 GO:0060988 lipid tube assembly(GO:0060988)
0.2 0.5 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.2 1.3 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.2 0.5 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.2 0.5 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 1.3 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.9 GO:0071321 cellular response to cGMP(GO:0071321)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 3.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.7 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.5 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.8 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.5 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.3 GO:0071336 proximal/distal axis specification(GO:0009946) bronchiole development(GO:0060435) bud outgrowth involved in lung branching(GO:0060447) submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.6 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1 0.3 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.6 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.6 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.5 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.7 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.3 GO:0090107 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.5 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 1.1 GO:0000022 mitotic spindle elongation(GO:0000022)
0.1 0.4 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 1.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.6 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.3 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.2 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.6 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.1 0.6 GO:0070141 response to UV-A(GO:0070141)
0.1 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.2 GO:0060935 myofibroblast differentiation(GO:0036446) cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) regulation of myofibroblast differentiation(GO:1904760)
0.1 1.1 GO:0036010 protein localization to endosome(GO:0036010)
0.1 0.5 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.7 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.4 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.4 GO:0060318 regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.3 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.9 GO:0045116 protein neddylation(GO:0045116)
0.0 0.5 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.2 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.6 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0035624 receptor transactivation(GO:0035624)
0.0 1.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.7 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.6 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 1.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.0 0.1 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.2 GO:0030201 heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0 0.1 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.8 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.5 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.1 GO:0072179 nephric duct formation(GO:0072179)
0.0 0.1 GO:0048022 cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.2 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.3 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.1 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.0 0.1 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.7 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.5 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.4 GO:0007398 ectoderm development(GO:0007398)
0.0 0.0 GO:0061386 closure of optic fissure(GO:0061386)
0.0 2.1 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.1 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.3 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.8 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.0 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.5 3.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 0.6 GO:0098855 HCN channel complex(GO:0098855)
0.2 0.7 GO:0000811 GINS complex(GO:0000811)
0.2 0.8 GO:0097149 centralspindlin complex(GO:0097149)
0.1 1.0 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.6 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.8 GO:0070695 FHF complex(GO:0070695)
0.1 0.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.1 GO:0070938 contractile ring(GO:0070938)
0.1 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.0 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 1.0 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.6 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0051286 cell tip(GO:0051286)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 3.3 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 3.9 GO:0001726 ruffle(GO:0001726)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.0 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 1.4 GO:0030175 filopodium(GO:0030175)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.1 GO:0000922 spindle pole(GO:0000922)
0.0 1.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.6 2.9 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.5 1.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.0 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.3 1.3 GO:0038025 reelin receptor activity(GO:0038025)
0.2 0.7 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.9 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 2.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.2 0.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 1.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.3 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.5 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 1.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.3 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.6 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.7 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.4 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 3.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266) BH3 domain binding(GO:0051434)
0.0 0.1 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.6 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0042974 retinoic acid receptor binding(GO:0042974)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 3.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 2.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 PID EPO PATHWAY EPO signaling pathway
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.8 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 3.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.9 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.6 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins