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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ALX3

Z-value: 0.66

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Transcription factors associated with ALX3

Gene Symbol Gene ID Gene Info
ALX3
ENSG00000156150.6 ALX homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ALX3hg19_v2_chr1_-_110613276_110613322-0.193.0e-01Click!

Activity profile of ALX3 motif

Sorted Z-values of ALX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_25348007 4.24 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr5_-_35938674 3.52 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL
calcyphosine-like
chr11_+_101918153 3.43 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70
chromosome 11 open reading frame 70
chr12_+_7013897 3.16 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr12_+_7014064 3.12 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr12_+_7014126 2.32 ENST00000415834.1
ENST00000436789.1
LRRC23
leucine rich repeat containing 23
chr12_-_10282836 2.14 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr11_-_63376013 2.03 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr16_-_55866997 1.75 ENST00000360526.3
ENST00000361503.4
CES1
carboxylesterase 1
chr11_+_71900703 1.73 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr9_-_117111222 1.72 ENST00000374079.4
AKNA
AT-hook transcription factor
chr11_+_71900572 1.70 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr12_-_10282681 1.59 ENST00000533022.1
CLEC7A
C-type lectin domain family 7, member A
chr16_-_28634874 1.57 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr12_-_10282742 1.55 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr4_+_86525299 1.44 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr13_-_86373536 1.40 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr14_-_54423529 1.28 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr1_+_47533160 1.27 ENST00000334194.3
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr4_-_70518941 1.27 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr16_-_28608364 1.26 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr16_-_28608424 1.15 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr16_-_28621353 1.14 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr4_-_25865159 1.12 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr17_+_35851570 1.11 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr1_-_150738261 1.04 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr19_+_50016411 0.99 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr3_+_140396881 0.97 ENST00000286349.3
TRIM42
tripartite motif containing 42
chr16_-_28937027 0.95 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr16_-_28621312 0.95 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr19_+_50016610 0.94 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr19_+_49199209 0.93 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2
fucosyltransferase 2 (secretor status included)
chr11_+_100862811 0.88 ENST00000303130.2
TMEM133
transmembrane protein 133
chr17_+_1674982 0.82 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr8_+_105235572 0.82 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr14_+_74034310 0.82 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr9_+_90112767 0.81 ENST00000408954.3
DAPK1
death-associated protein kinase 1
chr7_+_48211048 0.79 ENST00000435803.1
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr1_+_28261492 0.77 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr10_+_695888 0.74 ENST00000441152.2
PRR26
proline rich 26
chr16_-_28621298 0.73 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr4_-_138453559 0.72 ENST00000511115.1
PCDH18
protocadherin 18
chr1_+_28261621 0.71 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr9_+_90112741 0.69 ENST00000469640.2
DAPK1
death-associated protein kinase 1
chrX_+_77154935 0.69 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr9_+_90112590 0.68 ENST00000472284.1
DAPK1
death-associated protein kinase 1
chr9_+_90112117 0.64 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr12_+_131438443 0.62 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr11_+_6897856 0.61 ENST00000379829.2
OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr10_-_28571015 0.61 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr6_+_26402465 0.60 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr5_-_20575959 0.59 ENST00000507958.1
CDH18
cadherin 18, type 2
chr13_+_24144796 0.56 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr2_+_217524323 0.55 ENST00000456764.1
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr4_+_37455536 0.55 ENST00000381980.4
ENST00000508175.1
C4orf19
chromosome 4 open reading frame 19
chr5_-_96478466 0.54 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr3_-_191000172 0.54 ENST00000427544.2
UTS2B
urotensin 2B
chr3_+_195447738 0.53 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr19_+_42580274 0.52 ENST00000359044.4
ZNF574
zinc finger protein 574
chr7_-_111032971 0.52 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr16_+_31885079 0.52 ENST00000300870.10
ENST00000394846.3
ZNF267
zinc finger protein 267
chr11_+_57480046 0.51 ENST00000378312.4
ENST00000278422.4
TMX2
thioredoxin-related transmembrane protein 2
chr15_-_98417780 0.50 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr1_+_12976450 0.49 ENST00000361079.2
PRAMEF7
PRAME family member 7
chr13_+_78315295 0.48 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr6_+_26402517 0.47 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr18_-_53303123 0.47 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr1_+_117544366 0.45 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr14_-_78083112 0.45 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr1_-_190446759 0.45 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr5_+_140557371 0.44 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr12_-_46121554 0.42 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr16_+_31724552 0.42 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
ZNF720
zinc finger protein 720
chr22_-_32651326 0.42 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr8_-_102803163 0.42 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chrX_+_130192318 0.41 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr6_+_26440700 0.40 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr11_+_7618413 0.40 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_-_66536196 0.39 ENST00000511294.1
EPHA5
EPH receptor A5
chr1_-_54411240 0.39 ENST00000371378.2
HSPB11
heat shock protein family B (small), member 11
chr1_-_150669500 0.39 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr1_-_54411255 0.39 ENST00000371377.3
HSPB11
heat shock protein family B (small), member 11
chr2_-_43266680 0.39 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2
AC016735.2
chr4_+_86699834 0.38 ENST00000395183.2
ARHGAP24
Rho GTPase activating protein 24
chr5_-_94417339 0.38 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr6_+_52442083 0.38 ENST00000606714.1
TRAM2-AS1
TRAM2 antisense RNA 1 (head to head)
chr7_+_133812052 0.37 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr20_-_29978286 0.37 ENST00000376315.2
DEFB119
defensin, beta 119
chr4_+_113568207 0.37 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr1_+_160370344 0.37 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr11_-_128894053 0.36 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chrX_-_13835147 0.35 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr15_-_89755034 0.34 ENST00000563254.1
RLBP1
retinaldehyde binding protein 1
chr9_+_105757590 0.34 ENST00000374798.3
ENST00000487798.1
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr1_+_225600404 0.33 ENST00000366845.2
AC092811.1
AC092811.1
chr20_-_50418947 0.32 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr3_+_138340049 0.32 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr20_-_50418972 0.31 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr2_+_103089756 0.30 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chrX_+_36254051 0.30 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr14_+_39736582 0.29 ENST00000556148.1
ENST00000348007.3
CTAGE5
CTAGE family, member 5
chr19_+_47421933 0.29 ENST00000404338.3
ARHGAP35
Rho GTPase activating protein 35
chr4_-_120243545 0.28 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr17_-_39341594 0.27 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr16_-_66584059 0.26 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2
thymidine kinase 2, mitochondrial
chr17_-_4938712 0.26 ENST00000254853.5
ENST00000424747.1
SLC52A1
solute carrier family 52 (riboflavin transporter), member 1
chr7_-_43965937 0.26 ENST00000455877.1
ENST00000223341.7
ENST00000447717.3
ENST00000426198.1
URGCP
upregulator of cell proliferation
chr2_+_234826016 0.26 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr3_+_138340067 0.25 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr15_+_44719970 0.25 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr12_+_8666126 0.25 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr2_-_152118352 0.25 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr16_+_53133070 0.24 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr7_+_138145076 0.24 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr11_+_92702886 0.24 ENST00000257068.2
ENST00000528076.1
MTNR1B
melatonin receptor 1B
chr12_+_66582919 0.24 ENST00000545837.1
ENST00000457197.2
IRAK3
interleukin-1 receptor-associated kinase 3
chrX_+_108779004 0.24 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr4_-_66536057 0.23 ENST00000273854.3
EPHA5
EPH receptor A5
chr10_+_91152303 0.23 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr5_+_176811431 0.23 ENST00000512593.1
ENST00000324417.5
SLC34A1
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr17_-_39191107 0.22 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr14_+_55493920 0.22 ENST00000395472.2
ENST00000555846.1
SOCS4
suppressor of cytokine signaling 4
chr8_+_107738240 0.22 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr9_-_5339873 0.22 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr2_+_135596180 0.21 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr5_+_140201183 0.21 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
PCDHA5
protocadherin alpha 5
chr3_-_160823040 0.21 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr5_+_140762268 0.21 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr8_-_93978357 0.21 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK
triple QxxK/R motif containing
chr3_-_160823158 0.20 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr2_+_113299990 0.20 ENST00000537335.1
ENST00000417433.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr15_-_75748115 0.20 ENST00000360439.4
SIN3A
SIN3 transcription regulator family member A
chr12_-_122985067 0.20 ENST00000540586.1
ENST00000543897.1
ZCCHC8
zinc finger, CCHC domain containing 8
chr14_+_55494323 0.20 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr2_-_89340242 0.20 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr7_-_149158187 0.20 ENST00000247930.4
ZNF777
zinc finger protein 777
chr17_+_18086392 0.19 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr6_-_32095968 0.19 ENST00000375203.3
ENST00000375201.4
ATF6B
activating transcription factor 6 beta
chr5_+_140227357 0.19 ENST00000378122.3
PCDHA9
protocadherin alpha 9
chr2_+_135596106 0.19 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr9_+_12775011 0.19 ENST00000319264.3
LURAP1L
leucine rich adaptor protein 1-like
chr15_-_37393406 0.18 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr11_+_5710919 0.18 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr2_-_231860596 0.18 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
AC105344.2
SPATA3 antisense RNA 1 (head to head)
chr14_+_22977587 0.17 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr7_+_43966018 0.16 ENST00000222402.3
ENST00000446008.1
ENST00000394798.4
UBE2D4
ubiquitin-conjugating enzyme E2D 4 (putative)
chr1_-_150669604 0.16 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chr3_+_186353756 0.16 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB
fetuin B
chr10_+_90660832 0.16 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr11_-_13011081 0.16 ENST00000532541.1
ENST00000526388.1
ENST00000534477.1
ENST00000531402.1
ENST00000527945.1
ENST00000504230.2
LINC00958
long intergenic non-protein coding RNA 958
chr7_-_87856280 0.15 ENST00000490437.1
ENST00000431660.1
SRI
sorcin
chr9_-_116065551 0.15 ENST00000297894.5
RNF183
ring finger protein 183
chr7_-_92777606 0.15 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr2_-_3521518 0.15 ENST00000382093.5
ADI1
acireductone dioxygenase 1
chr1_-_92952433 0.15 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr7_-_87856303 0.14 ENST00000394641.3
SRI
sorcin
chr6_-_36515177 0.14 ENST00000229812.7
STK38
serine/threonine kinase 38
chr1_-_24306768 0.14 ENST00000374453.3
ENST00000453840.3
SRSF10
serine/arginine-rich splicing factor 10
chr5_-_159846399 0.14 ENST00000297151.4
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr11_-_327537 0.13 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr9_-_28670283 0.13 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr12_-_118796910 0.13 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr19_+_36139125 0.13 ENST00000246554.3
COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chr6_+_161123270 0.13 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG
plasminogen
chr1_-_151431647 0.12 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr5_+_68860949 0.12 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr4_-_103748880 0.12 ENST00000453744.2
ENST00000349311.8
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr8_-_116504448 0.12 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr2_-_220264703 0.12 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP
aspartyl aminopeptidase
chr19_-_44388116 0.11 ENST00000587539.1
ZNF404
zinc finger protein 404
chr22_-_40289759 0.11 ENST00000325157.6
ENTHD1
ENTH domain containing 1
chr20_-_33735070 0.11 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr1_+_15668240 0.10 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr10_+_24755416 0.10 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr4_-_122686261 0.10 ENST00000337677.5
TMEM155
transmembrane protein 155
chr5_+_140579162 0.10 ENST00000536699.1
ENST00000354757.3
PCDHB11
protocadherin beta 11
chr11_+_2405833 0.10 ENST00000527343.1
ENST00000464784.2
CD81
CD81 molecule
chr3_+_148709128 0.10 ENST00000345003.4
ENST00000296048.6
ENST00000483267.1
GYG1
glycogenin 1
chr6_+_154360357 0.10 ENST00000330432.7
ENST00000360422.4
OPRM1
opioid receptor, mu 1
chr14_+_22465771 0.09 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr9_-_34729457 0.09 ENST00000378788.3
FAM205A
family with sequence similarity 205, member A
chr16_+_12059091 0.09 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr7_+_99202003 0.09 ENST00000609449.1
GS1-259H13.2
GS1-259H13.2
chr8_-_93978309 0.09 ENST00000517858.1
ENST00000378861.5
TRIQK
triple QxxK/R motif containing
chr20_-_43133491 0.09 ENST00000411544.1
SERINC3
serine incorporator 3
chr19_-_51920952 0.08 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr16_+_72088376 0.08 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr1_-_202897724 0.08 ENST00000435533.3
ENST00000367258.1
KLHL12
kelch-like family member 12
chr20_-_29978383 0.08 ENST00000339144.3
ENST00000376321.3
DEFB119
defensin, beta 119
chr6_-_87804815 0.07 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr4_-_74486109 0.07 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr8_-_93978346 0.07 ENST00000523580.1
TRIQK
triple QxxK/R motif containing
chr3_+_45927994 0.07 ENST00000357632.2
ENST00000395963.2
CCR9
chemokine (C-C motif) receptor 9
chr11_+_55650773 0.07 ENST00000449290.2
TRIM51
tripartite motif-containing 51
chr19_-_3557570 0.07 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr4_-_74486347 0.07 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr15_+_75970672 0.06 ENST00000435356.1
AC105020.1
Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr8_-_93978333 0.06 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
TRIQK
triple QxxK/R motif containing
chr1_-_24306798 0.06 ENST00000374452.5
ENST00000492112.2
ENST00000343255.5
ENST00000344989.6
SRSF10
serine/arginine-rich splicing factor 10
chr2_-_228497888 0.06 ENST00000264387.4
ENST00000409066.1
C2orf83
chromosome 2 open reading frame 83

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.4 1.8 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.4 1.3 GO:0055020 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.3 6.8 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 5.3 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.2 1.4 GO:0060005 vestibular reflex(GO:0060005)
0.2 1.9 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.2 2.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 0.5 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.4 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.7 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.4 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 2.9 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 1.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.8 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.2 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.9 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.6 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.3 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.4 GO:0034627 quinolinate biosynthetic process(GO:0019805) 'de novo' NAD biosynthetic process(GO:0034627)
0.1 1.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.3 GO:0050955 thermoception(GO:0050955)
0.1 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.6 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 1.1 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.8 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.3 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 1.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.4 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:2000296 regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.4 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 1.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.3 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.8 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.5 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.5 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.4 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 3.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.0 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.3 GO:0033150 cytoskeletal calyx(GO:0033150)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 0.8 GO:0043203 axon hillock(GO:0043203)
0.1 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.4 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 1.9 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 2.0 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.8 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.9 3.4 GO:0061714 folic acid receptor activity(GO:0061714)
0.5 1.9 GO:0019770 IgG receptor activity(GO:0019770)
0.4 2.0 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.4 1.8 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 5.3 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 0.4 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 1.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0004797 thymidine kinase activity(GO:0004797)
0.1 2.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.3 GO:0070330 aromatase activity(GO:0070330)
0.1 0.9 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 1.0 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.8 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.8 PID IFNG PATHWAY IFN-gamma pathway
0.0 5.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 2.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis