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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ATF5

Z-value: 0.82

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Transcription factors associated with ATF5

Gene Symbol Gene ID Gene Info
ATF5
ENSG00000169136.4 activating transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF5hg19_v2_chr19_+_50431959_50431998-0.346.2e-02Click!

Activity profile of ATF5 motif

Sorted Z-values of ATF5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_41740181 3.47 ENST00000442711.1
INHBA
inhibin, beta A
chr5_-_39219705 3.37 ENST00000351578.6
FYB
FYN binding protein
chr1_-_17304771 3.01 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chr5_-_39219641 2.49 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYB
FYN binding protein
chr2_-_113542063 2.31 ENST00000263339.3
IL1A
interleukin 1, alpha
chr5_+_156887027 2.03 ENST00000435489.2
ENST00000311946.7
NIPAL4
NIPA-like domain containing 4
chr1_+_209859510 1.77 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr6_+_43738444 1.60 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA
vascular endothelial growth factor A
chr12_-_25101920 1.53 ENST00000539780.1
ENST00000546285.1
ENST00000342945.5
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr5_+_154393260 1.46 ENST00000435029.4
KIF4B
kinesin family member 4B
chr2_-_26205340 1.41 ENST00000264712.3
KIF3C
kinesin family member 3C
chr15_+_80733570 1.29 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr19_-_44285401 1.22 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_+_16083154 1.19 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr11_+_124735282 1.18 ENST00000397801.1
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr20_+_58179582 1.18 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr16_-_72127456 1.07 ENST00000562153.1
TXNL4B
thioredoxin-like 4B
chr7_-_3083573 0.96 ENST00000396946.4
CARD11
caspase recruitment domain family, member 11
chr3_+_101504200 0.86 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr6_-_88411911 0.86 ENST00000257787.5
AKIRIN2
akirin 2
chr4_+_77172847 0.79 ENST00000515604.1
ENST00000539752.1
ENST00000424749.2
FAM47E
FAM47E-STBD1
FAM47E
uncharacterized protein LOC100631383
FAM47E-STBD1 readthrough
family with sequence similarity 47, member E
chr17_+_33914460 0.78 ENST00000537622.2
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr5_+_137203465 0.78 ENST00000239926.4
MYOT
myotilin
chr11_-_11747257 0.77 ENST00000601641.1
AC131935.1
AC131935.1
chr1_+_206579736 0.74 ENST00000439126.1
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr14_-_36988882 0.72 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr2_+_234601512 0.71 ENST00000305139.6
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr15_+_63481668 0.71 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B
RAB8B, member RAS oncogene family
chr17_+_33914276 0.71 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr7_+_150688166 0.70 ENST00000461406.1
NOS3
nitric oxide synthase 3 (endothelial cell)
chr4_-_159956333 0.69 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr14_+_50065459 0.68 ENST00000318317.4
LRR1
leucine rich repeat protein 1
chrX_+_131157609 0.65 ENST00000496850.1
MST4
Serine/threonine-protein kinase MST4
chr12_-_72057638 0.65 ENST00000552037.1
ENST00000378743.3
ZFC3H1
zinc finger, C3H1-type containing
chr8_-_131028869 0.62 ENST00000518283.1
ENST00000519110.1
FAM49B
family with sequence similarity 49, member B
chr12_+_56915776 0.61 ENST00000550726.1
ENST00000542360.1
RBMS2
RNA binding motif, single stranded interacting protein 2
chr2_-_188419078 0.61 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr7_+_73498118 0.61 ENST00000336180.2
LIMK1
LIM domain kinase 1
chr12_+_125811162 0.60 ENST00000299308.3
TMEM132B
transmembrane protein 132B
chr3_-_99569821 0.59 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr12_+_32655048 0.58 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr14_+_23845995 0.58 ENST00000359320.3
CMTM5
CKLF-like MARVEL transmembrane domain containing 5
chr12_-_56843161 0.57 ENST00000554616.1
ENST00000553532.1
ENST00000229201.4
TIMELESS
timeless circadian clock
chr2_-_190927447 0.57 ENST00000260950.4
MSTN
myostatin
chr14_+_100111447 0.57 ENST00000330710.5
ENST00000357223.2
HHIPL1
HHIP-like 1
chr2_-_188419200 0.57 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr14_+_23846210 0.57 ENST00000339180.4
ENST00000342473.4
ENST00000397227.3
ENST00000555731.1
CMTM5
CKLF-like MARVEL transmembrane domain containing 5
chr20_+_62492566 0.56 ENST00000369916.3
ABHD16B
abhydrolase domain containing 16B
chr19_+_48969094 0.55 ENST00000595676.1
CTC-273B12.7
Uncharacterized protein
chr14_+_50065376 0.55 ENST00000298288.6
LRR1
leucine rich repeat protein 1
chr2_-_87018784 0.54 ENST00000283635.3
ENST00000538832.1
CD8A
CD8a molecule
chr11_+_57310114 0.54 ENST00000527972.1
ENST00000399154.2
SMTNL1
smoothelin-like 1
chr3_-_47950745 0.53 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr5_+_34757309 0.52 ENST00000397449.1
RAI14
retinoic acid induced 14
chr8_+_38677850 0.52 ENST00000518809.1
ENST00000520611.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr22_-_36236623 0.51 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr4_+_159443090 0.50 ENST00000343542.5
ENST00000470033.1
RXFP1
relaxin/insulin-like family peptide receptor 1
chr22_-_36357671 0.49 ENST00000408983.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr12_+_56915713 0.48 ENST00000262031.5
ENST00000552247.2
RBMS2
RNA binding motif, single stranded interacting protein 2
chr6_+_29079668 0.48 ENST00000377169.1
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr4_+_159442878 0.48 ENST00000307765.5
ENST00000423548.1
RXFP1
relaxin/insulin-like family peptide receptor 1
chr19_-_38916802 0.46 ENST00000587738.1
RASGRP4
RAS guanyl releasing protein 4
chr7_+_128399002 0.45 ENST00000493278.1
CALU
calumenin
chr2_-_87017985 0.44 ENST00000352580.3
CD8A
CD8a molecule
chr8_-_95449155 0.43 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chrX_+_122318318 0.43 ENST00000371251.1
ENST00000371256.5
GRIA3
glutamate receptor, ionotropic, AMPA 3
chrX_+_122318006 0.43 ENST00000371266.1
ENST00000264357.5
GRIA3
glutamate receptor, ionotropic, AMPA 3
chrX_+_122318224 0.42 ENST00000542149.1
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr9_+_116917807 0.42 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr12_-_54778471 0.41 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
ZNF385A
zinc finger protein 385A
chr12_+_10124001 0.40 ENST00000396507.3
ENST00000304361.4
ENST00000434319.2
CLEC12A
C-type lectin domain family 12, member A
chr15_-_75871589 0.39 ENST00000306726.2
PTPN9
protein tyrosine phosphatase, non-receptor type 9
chr18_-_24283586 0.39 ENST00000579458.1
U3
Small nucleolar RNA U3
chr12_-_16761007 0.39 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr14_+_70918874 0.38 ENST00000603540.1
ADAM21
ADAM metallopeptidase domain 21
chr5_+_137203541 0.38 ENST00000421631.2
MYOT
myotilin
chr16_+_28943260 0.38 ENST00000538922.1
ENST00000324662.3
ENST00000567541.1
CD19
CD19 molecule
chr5_+_137203557 0.38 ENST00000515645.1
MYOT
myotilin
chr16_+_72127670 0.37 ENST00000536867.1
DHX38
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr9_+_2621798 0.37 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr16_+_72127461 0.36 ENST00000268482.3
ENST00000566794.1
DHX38
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr8_-_100025238 0.36 ENST00000521696.1
RP11-410L14.2
RP11-410L14.2
chr1_-_27930102 0.35 ENST00000247087.5
ENST00000374011.2
AHDC1
AT hook, DNA binding motif, containing 1
chr3_+_38206975 0.35 ENST00000446845.1
ENST00000311806.3
OXSR1
oxidative stress responsive 1
chr10_+_102505468 0.34 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
PAX2
paired box 2
chr2_-_208994548 0.34 ENST00000282141.3
CRYGC
crystallin, gamma C
chr17_-_73149921 0.34 ENST00000481647.1
ENST00000470924.1
HN1
hematological and neurological expressed 1
chr12_-_1920886 0.34 ENST00000536846.2
ENST00000538027.2
ENST00000538450.1
CACNA2D4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr4_+_159443024 0.34 ENST00000448688.2
RXFP1
relaxin/insulin-like family peptide receptor 1
chr5_+_82767487 0.33 ENST00000343200.5
ENST00000342785.4
VCAN
versican
chr6_-_132967142 0.32 ENST00000275216.1
TAAR1
trace amine associated receptor 1
chr5_+_175223313 0.32 ENST00000359546.4
CPLX2
complexin 2
chr6_+_114178512 0.32 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr5_+_82767284 0.31 ENST00000265077.3
VCAN
versican
chr2_-_209119831 0.30 ENST00000345146.2
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr9_+_2622085 0.30 ENST00000382099.2
VLDLR
very low density lipoprotein receptor
chr8_+_22462532 0.30 ENST00000389279.3
CCAR2
cell cycle and apoptosis regulator 2
chr22_-_36236265 0.30 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr19_-_38916839 0.30 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RASGRP4
RAS guanyl releasing protein 4
chr1_+_66999799 0.29 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr9_-_71155783 0.29 ENST00000377311.3
TMEM252
transmembrane protein 252
chr16_-_72128270 0.29 ENST00000426362.2
TXNL4B
thioredoxin-like 4B
chr2_-_209118974 0.29 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr8_-_623547 0.29 ENST00000522893.1
ERICH1
glutamate-rich 1
chr9_-_38069208 0.28 ENST00000377707.3
ENST00000377700.4
SHB
Src homology 2 domain containing adaptor protein B
chr16_-_72127550 0.27 ENST00000268483.3
TXNL4B
thioredoxin-like 4B
chr22_-_37215523 0.27 ENST00000216200.5
PVALB
parvalbumin
chr5_+_82767583 0.27 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN
versican
chr20_+_54987305 0.27 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr20_+_54987168 0.27 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chrX_+_122318113 0.27 ENST00000371264.3
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr12_-_115121962 0.27 ENST00000349155.2
TBX3
T-box 3
chr2_-_128784846 0.26 ENST00000259235.3
ENST00000357702.5
ENST00000424298.1
SAP130
Sin3A-associated protein, 130kDa
chr7_-_115670792 0.26 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr19_+_15160130 0.26 ENST00000427043.3
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr19_-_38916822 0.26 ENST00000586305.1
RASGRP4
RAS guanyl releasing protein 4
chr3_-_62860878 0.26 ENST00000283269.9
CADPS
Ca++-dependent secretion activator
chr16_+_30075463 0.25 ENST00000562168.1
ENST00000569545.1
ALDOA
aldolase A, fructose-bisphosphate
chr8_+_22462145 0.25 ENST00000308511.4
ENST00000523801.1
ENST00000521301.1
CCAR2
cell cycle and apoptosis regulator 2
chr2_-_145278475 0.25 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr12_-_52967600 0.25 ENST00000549343.1
ENST00000305620.2
KRT74
keratin 74
chr1_+_151739131 0.25 ENST00000400999.1
OAZ3
ornithine decarboxylase antizyme 3
chr7_-_115670804 0.24 ENST00000320239.7
TFEC
transcription factor EC
chr2_+_153191706 0.24 ENST00000288670.9
FMNL2
formin-like 2
chr18_-_19748379 0.24 ENST00000579431.1
GATA6-AS1
GATA6 antisense RNA 1 (head to head)
chr3_-_62861012 0.23 ENST00000357948.3
ENST00000383710.4
CADPS
Ca++-dependent secretion activator
chr5_+_92919043 0.23 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr9_-_23825956 0.23 ENST00000397312.2
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr5_-_134788086 0.23 ENST00000537858.1
TIFAB
TRAF-interacting protein with forkhead-associated domain, family member B
chr12_+_120884222 0.22 ENST00000551765.1
ENST00000229384.5
GATC
glutamyl-tRNA(Gln) amidotransferase, subunit C
chr7_+_132937820 0.21 ENST00000393161.2
ENST00000253861.4
EXOC4
exocyst complex component 4
chr1_-_67896009 0.20 ENST00000370990.5
SERBP1
SERPINE1 mRNA binding protein 1
chr10_+_135207623 0.20 ENST00000317502.6
ENST00000432508.3
MTG1
mitochondrial ribosome-associated GTPase 1
chr18_-_812517 0.19 ENST00000584307.1
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr18_-_812231 0.19 ENST00000314574.4
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr9_-_23826298 0.19 ENST00000380117.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr2_-_100759037 0.19 ENST00000317233.4
ENST00000423966.1
ENST00000416492.1
AFF3
AF4/FMR2 family, member 3
chr3_-_62860704 0.18 ENST00000490353.2
CADPS
Ca++-dependent secretion activator
chr12_-_49351303 0.18 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr5_+_79615790 0.18 ENST00000296739.4
SPZ1
spermatogenic leucine zipper 1
chr1_-_22109682 0.18 ENST00000400301.1
ENST00000532737.1
USP48
ubiquitin specific peptidase 48
chr22_-_26875345 0.18 ENST00000398141.1
HPS4
Hermansky-Pudlak syndrome 4
chr11_+_62496114 0.18 ENST00000532583.1
TTC9C
tetratricopeptide repeat domain 9C
chr5_+_148786518 0.18 ENST00000518014.1
ENST00000505340.1
ENST00000509909.1
AC131025.8
MIR143HG
AC131025.8
MIR143 host gene (non-protein coding)
chr1_-_27286897 0.17 ENST00000320567.5
C1orf172
chromosome 1 open reading frame 172
chr3_+_19988566 0.17 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr11_-_6462210 0.17 ENST00000265983.3
HPX
hemopexin
chr11_+_62495997 0.17 ENST00000316461.4
TTC9C
tetratricopeptide repeat domain 9C
chr19_-_45926739 0.17 ENST00000589381.1
ENST00000591636.1
ENST00000013807.5
ENST00000592023.1
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr6_-_39902160 0.16 ENST00000340692.5
MOCS1
molybdenum cofactor synthesis 1
chr12_+_56415100 0.16 ENST00000547791.1
IKZF4
IKAROS family zinc finger 4 (Eos)
chr8_-_13134045 0.16 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr18_-_3845293 0.16 ENST00000400145.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr14_+_79746249 0.16 ENST00000428277.2
NRXN3
neurexin 3
chrX_-_44402231 0.15 ENST00000378045.4
FUNDC1
FUN14 domain containing 1
chr2_-_114514181 0.15 ENST00000409342.1
SLC35F5
solute carrier family 35, member F5
chr1_-_22109484 0.15 ENST00000529637.1
USP48
ubiquitin specific peptidase 48
chr13_-_36944307 0.15 ENST00000355182.4
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr15_-_90222642 0.14 ENST00000430628.2
PLIN1
perilipin 1
chr5_+_132009675 0.14 ENST00000231449.2
ENST00000350025.2
IL4
interleukin 4
chr15_-_90222610 0.14 ENST00000300055.5
PLIN1
perilipin 1
chr12_-_54652060 0.14 ENST00000552562.1
CBX5
chromobox homolog 5
chr18_-_19748331 0.14 ENST00000584201.1
GATA6-AS1
GATA6 antisense RNA 1 (head to head)
chr16_-_65155979 0.14 ENST00000562325.1
ENST00000268603.4
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr12_-_120884175 0.14 ENST00000546954.1
TRIAP1
TP53 regulated inhibitor of apoptosis 1
chr10_+_103113840 0.13 ENST00000393441.4
ENST00000408038.2
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
chr17_-_47287928 0.13 ENST00000507680.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr6_-_100016678 0.13 ENST00000523799.1
ENST00000520429.1
CCNC
cyclin C
chr3_+_19988885 0.13 ENST00000422242.1
RAB5A
RAB5A, member RAS oncogene family
chr1_+_101361782 0.13 ENST00000357650.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr14_+_79745746 0.13 ENST00000281127.7
NRXN3
neurexin 3
chr16_-_65155833 0.12 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr3_-_182698381 0.12 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr7_-_102232891 0.12 ENST00000514917.2
RP11-514P8.7
RP11-514P8.7
chrX_+_153409678 0.12 ENST00000369951.4
OPN1LW
opsin 1 (cone pigments), long-wave-sensitive
chr1_-_156460391 0.12 ENST00000360595.3
MEF2D
myocyte enhancer factor 2D
chr8_+_79428539 0.12 ENST00000352966.5
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr2_-_113999260 0.11 ENST00000468980.2
PAX8
paired box 8
chr2_-_87248975 0.11 ENST00000409310.2
ENST00000355705.3
PLGLB1
plasminogen-like B1
chr1_-_11863571 0.11 ENST00000376583.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr16_+_19567016 0.11 ENST00000251143.5
ENST00000417362.2
ENST00000567245.1
ENST00000513947.4
C16orf62
chromosome 16 open reading frame 62
chr17_+_18761417 0.11 ENST00000419284.2
ENST00000268835.2
ENST00000412418.1
ENST00000575228.1
ENST00000575102.1
ENST00000536323.1
PRPSAP2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr4_+_84377198 0.10 ENST00000507349.1
ENST00000509970.1
ENST00000505719.1
MRPS18C
mitochondrial ribosomal protein S18C
chr1_+_202091980 0.10 ENST00000367282.5
GPR37L1
G protein-coupled receptor 37 like 1
chr2_+_189839046 0.09 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr6_-_100016527 0.09 ENST00000523985.1
ENST00000518714.1
ENST00000520371.1
CCNC
cyclin C
chr2_-_26700900 0.09 ENST00000338581.6
ENST00000339598.3
ENST00000402415.3
OTOF
otoferlin
chr3_-_69129501 0.09 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3
ubiquitin-like modifier activating enzyme 3
chr17_-_79817091 0.09 ENST00000570907.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr12_-_57030115 0.09 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr4_-_84376953 0.09 ENST00000510985.1
ENST00000295488.3
HELQ
helicase, POLQ-like
chr14_-_44976474 0.08 ENST00000340446.4
FSCB
fibrous sheath CABYR binding protein
chr16_+_9185450 0.08 ENST00000327827.7
C16orf72
chromosome 16 open reading frame 72
chr16_-_72206034 0.08 ENST00000537465.1
ENST00000237353.10
PMFBP1
polyamine modulated factor 1 binding protein 1
chr1_-_67896069 0.08 ENST00000370995.2
ENST00000361219.6
SERBP1
SERPINE1 mRNA binding protein 1
chr2_-_128642434 0.07 ENST00000393001.1
AMMECR1L
AMMECR1-like
chr17_-_46691990 0.07 ENST00000576562.1
HOXB8
homeobox B8
chr17_+_33474860 0.07 ENST00000394570.2
UNC45B
unc-45 homolog B (C. elegans)
chr17_+_33474826 0.06 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B
unc-45 homolog B (C. elegans)
chr3_-_183145765 0.06 ENST00000473233.1
MCF2L2
MCF.2 cell line derived transforming sequence-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.5 1.6 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.4 2.3 GO:2000391 positive regulation of neutrophil extravasation(GO:2000391)
0.3 3.0 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.3 1.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 1.5 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 0.7 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.2 1.0 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.2 0.7 GO:0014806 negative regulation of muscle hyperplasia(GO:0014740) smooth muscle hyperplasia(GO:0014806)
0.2 0.6 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 1.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 0.6 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 1.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 1.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.6 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.1 5.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 2.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.4 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.6 GO:0072719 cellular response to cisplatin(GO:0072719)
0.1 0.7 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.1 0.7 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.6 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.7 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.1 1.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.3 GO:0060931 sinoatrial node cell development(GO:0060931)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 1.8 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.4 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 1.2 GO:0046541 saliva secretion(GO:0046541)
0.1 1.0 GO:0070970 interleukin-2 secretion(GO:0070970)
0.1 0.2 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.1 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.7 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.4 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.7 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.6 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.3 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 1.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) post-embryonic hemopoiesis(GO:0035166)
0.0 1.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 1.0 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 1.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:2001138 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.5 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.4 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.0 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 0.6 GO:0044609 DBIRD complex(GO:0044609)
0.1 3.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 1.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.7 GO:0051286 cell tip(GO:0051286)
0.1 1.9 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.7 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.2 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 1.6 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 1.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 2.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.7 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 2.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 8.2 GO:0015629 actin cytoskeleton(GO:0015629)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.6 1.8 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 1.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 1.5 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 1.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 0.7 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.2 0.6 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.2 0.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 1.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.6 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 2.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 1.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.7 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 1.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.0 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.0 1.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 1.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 1.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 3.5 PID ALK1 PATHWAY ALK1 signaling events
0.1 6.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 2.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.7 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 3.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.7 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 5.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 3.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.9 REACTOME KINESINS Genes involved in Kinesins
0.1 1.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 2.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.6 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 1.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME OPSINS Genes involved in Opsins