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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for BACH2

Z-value: 0.58

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Transcription factors associated with BACH2

Gene Symbol Gene ID Gene Info
BACH2
ENSG00000112182.10 BTB domain and CNC homolog 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BACH2hg19_v2_chr6_-_91006461_91006517,
hg19_v2_chr6_-_91006627_91006641		-0.346.2e-02Click!

Activity profile of BACH2 motif

Sorted Z-values of BACH2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_150480551 4.15 ENST00000369049.4
ENST00000369047.4
ECM1
extracellular matrix protein 1
chr1_+_150480576 4.12 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr18_+_21452964 3.17 ENST00000587184.1
LAMA3
laminin, alpha 3
chr11_-_102668879 3.08 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr18_+_21452804 2.75 ENST00000269217.6
LAMA3
laminin, alpha 3
chr2_+_113875466 2.39 ENST00000361779.3
ENST00000259206.5
ENST00000354115.2
IL1RN
interleukin 1 receptor antagonist
chr19_-_36019123 2.23 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN
suprabasin
chr6_+_74405804 2.19 ENST00000287097.5
CD109
CD109 molecule
chr6_+_74405501 2.17 ENST00000437994.2
ENST00000422508.2
CD109
CD109 molecule
chr1_-_153521597 2.13 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr17_-_39769005 1.86 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr20_+_44637526 1.81 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr3_-_48632593 1.73 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr1_-_153521714 1.71 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr11_-_6341724 1.70 ENST00000530979.1
PRKCDBP
protein kinase C, delta binding protein
chr7_-_107643674 1.58 ENST00000222399.6
LAMB1
laminin, beta 1
chr11_-_102826434 1.54 ENST00000340273.4
ENST00000260302.3
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr1_+_152881014 1.52 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr11_-_62323702 1.51 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr18_+_61442629 1.46 ENST00000398019.2
ENST00000540675.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr11_-_6341844 1.38 ENST00000303927.3
PRKCDBP
protein kinase C, delta binding protein
chr2_+_48541776 1.32 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chr17_+_4853442 1.31 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr1_-_204121013 1.22 ENST00000367201.3
ETNK2
ethanolamine kinase 2
chr1_-_204121298 1.20 ENST00000367199.2
ETNK2
ethanolamine kinase 2
chr1_-_204121102 1.14 ENST00000367202.4
ETNK2
ethanolamine kinase 2
chr10_+_17270214 1.12 ENST00000544301.1
VIM
vimentin
chr11_-_65667997 1.09 ENST00000312562.2
ENST00000534222.1
FOSL1
FOS-like antigen 1
chr11_+_12308447 1.05 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr11_-_66104237 1.03 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr12_-_95009837 1.01 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr1_+_153003671 0.97 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr12_-_48152853 0.93 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr11_-_65667884 0.91 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr11_-_66103932 0.88 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr12_-_48152611 0.87 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr5_-_176923846 0.85 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr19_-_35992780 0.85 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr19_-_39264072 0.81 ENST00000599035.1
ENST00000378626.4
LGALS7
lectin, galactoside-binding, soluble, 7
chr1_-_6551720 0.79 ENST00000377728.3
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr4_+_74606223 0.78 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr20_-_1309809 0.78 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr17_-_76921459 0.77 ENST00000262768.7
TIMP2
TIMP metallopeptidase inhibitor 2
chr1_+_154377669 0.77 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr6_+_41604747 0.76 ENST00000419164.1
ENST00000373051.2
MDFI
MyoD family inhibitor
chr1_+_26606608 0.73 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr11_-_66103867 0.73 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr5_-_176923803 0.71 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr15_+_89182178 0.68 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr9_+_4985016 0.68 ENST00000539801.1
JAK2
Janus kinase 2
chr19_+_39279838 0.68 ENST00000314980.4
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr16_+_58533951 0.66 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG4
NDRG family member 4
chr3_-_98241358 0.62 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr19_-_51523412 0.62 ENST00000391805.1
ENST00000599077.1
KLK10
kallikrein-related peptidase 10
chr11_-_47207390 0.60 ENST00000539589.1
ENST00000528462.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr1_-_40157345 0.60 ENST00000372844.3
HPCAL4
hippocalcin like 4
chr1_+_26605618 0.59 ENST00000270792.5
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr9_+_4985228 0.59 ENST00000381652.3
JAK2
Janus kinase 2
chr6_-_35888905 0.58 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRPK1
SRSF protein kinase 1
chr19_-_51538118 0.58 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr18_+_268148 0.57 ENST00000581677.1
RP11-705O1.8
RP11-705O1.8
chr19_-_51538148 0.56 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr9_-_35112376 0.56 ENST00000488109.2
FAM214B
family with sequence similarity 214, member B
chr11_-_2924720 0.55 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr17_-_27503770 0.53 ENST00000533112.1
MYO18A
myosin XVIIIA
chr6_-_35888824 0.53 ENST00000361690.3
ENST00000512445.1
SRPK1
SRSF protein kinase 1
chr3_-_81792780 0.52 ENST00000489715.1
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr17_-_43502987 0.47 ENST00000376922.2
ARHGAP27
Rho GTPase activating protein 27
chr7_+_134528635 0.47 ENST00000445569.2
CALD1
caldesmon 1
chr8_-_68658578 0.47 ENST00000518549.1
ENST00000297770.4
ENST00000297769.4
CPA6
carboxypeptidase A6
chr5_+_149877334 0.46 ENST00000523767.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr2_-_85641162 0.46 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
CAPG
capping protein (actin filament), gelsolin-like
chrX_-_15511438 0.45 ENST00000380420.5
PIR
pirin (iron-binding nuclear protein)
chr1_-_6662919 0.45 ENST00000377658.4
ENST00000377663.3
KLHL21
kelch-like family member 21
chr13_+_32838801 0.45 ENST00000542859.1
FRY
furry homolog (Drosophila)
chr1_-_156675368 0.45 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chr17_-_39538550 0.45 ENST00000394001.1
KRT34
keratin 34
chr14_-_75643296 0.45 ENST00000303575.4
TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr20_-_634000 0.44 ENST00000381962.3
SRXN1
sulfiredoxin 1
chr19_-_51523275 0.44 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr1_+_156863470 0.43 ENST00000338302.3
ENST00000455314.1
ENST00000292357.7
PEAR1
platelet endothelial aggregation receptor 1
chr17_-_33390667 0.43 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr6_-_84140757 0.41 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr15_+_89181974 0.41 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr11_+_57308979 0.41 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr4_-_987217 0.41 ENST00000361661.2
ENST00000398516.2
SLC26A1
solute carrier family 26 (anion exchanger), member 1
chr3_-_151034734 0.41 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr1_-_179112173 0.41 ENST00000408940.3
ENST00000504405.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr1_+_156095951 0.40 ENST00000448611.2
ENST00000368297.1
LMNA
lamin A/C
chr17_-_27045405 0.40 ENST00000430132.2
RAB34
RAB34, member RAS oncogene family
chr15_-_99789736 0.39 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
TTC23
tetratricopeptide repeat domain 23
chr6_+_150070857 0.39 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr15_+_89182156 0.39 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr6_+_32121218 0.37 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2
palmitoyl-protein thioesterase 2
chr5_+_14664762 0.37 ENST00000284274.4
FAM105B
family with sequence similarity 105, member B
chr2_-_89459813 0.37 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr12_-_76478417 0.36 ENST00000552342.1
NAP1L1
nucleosome assembly protein 1-like 1
chr1_-_158656488 0.36 ENST00000368147.4
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr16_-_2908155 0.36 ENST00000571228.1
ENST00000161006.3
PRSS22
protease, serine, 22
chr5_-_175843569 0.35 ENST00000310418.4
ENST00000345807.2
CLTB
clathrin, light chain B
chr12_-_39299406 0.35 ENST00000331366.5
CPNE8
copine VIII
chr4_-_80329356 0.35 ENST00000358842.3
GK2
glycerol kinase 2
chr15_+_44829334 0.35 ENST00000535391.1
EIF3J
eukaryotic translation initiation factor 3, subunit J
chr12_-_76478386 0.35 ENST00000535020.2
NAP1L1
nucleosome assembly protein 1-like 1
chr17_-_27045427 0.33 ENST00000301043.6
ENST00000412625.1
RAB34
RAB34, member RAS oncogene family
chr16_-_122619 0.33 ENST00000262316.6
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr2_-_65593784 0.33 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chr22_+_20861858 0.32 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
MED15
mediator complex subunit 15
chr3_+_11178779 0.32 ENST00000438284.2
HRH1
histamine receptor H1
chr12_-_76478446 0.32 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
NAP1L1
nucleosome assembly protein 1-like 1
chr17_-_47287928 0.32 ENST00000507680.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr2_+_169926047 0.31 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr18_+_61143994 0.31 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr12_+_7023735 0.31 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
ENO2
enolase 2 (gamma, neuronal)
chr1_-_151965048 0.30 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr16_-_30125177 0.30 ENST00000406256.3
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr4_+_123747979 0.30 ENST00000608478.1
FGF2
fibroblast growth factor 2 (basic)
chr9_-_130341268 0.30 ENST00000373314.3
FAM129B
family with sequence similarity 129, member B
chr1_+_901847 0.30 ENST00000379410.3
ENST00000379409.2
ENST00000379407.3
PLEKHN1
pleckstrin homology domain containing, family N member 1
chr1_-_27816641 0.29 ENST00000430629.2
WASF2
WAS protein family, member 2
chr17_+_74734052 0.28 ENST00000590514.1
MFSD11
major facilitator superfamily domain containing 11
chr17_-_27045165 0.28 ENST00000436730.3
ENST00000450529.1
ENST00000583538.1
ENST00000419712.3
ENST00000580843.2
ENST00000582934.1
ENST00000415040.2
ENST00000353676.5
ENST00000453384.3
ENST00000447716.1
RAB34
RAB34, member RAS oncogene family
chr8_+_22844913 0.28 ENST00000519685.1
RHOBTB2
Rho-related BTB domain containing 2
chr1_+_36621697 0.27 ENST00000373150.4
ENST00000373151.2
MAP7D1
MAP7 domain containing 1
chrX_-_129244454 0.27 ENST00000308167.5
ELF4
E74-like factor 4 (ets domain transcription factor)
chr20_+_44034804 0.27 ENST00000357275.2
ENST00000372720.3
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr5_-_175843524 0.26 ENST00000502877.1
CLTB
clathrin, light chain B
chr6_+_106959718 0.26 ENST00000369066.3
AIM1
absent in melanoma 1
chr12_+_7023491 0.26 ENST00000541477.1
ENST00000229277.1
ENO2
enolase 2 (gamma, neuronal)
chr9_-_127177703 0.26 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
PSMB7
proteasome (prosome, macropain) subunit, beta type, 7
chrX_-_129244655 0.26 ENST00000335997.7
ELF4
E74-like factor 4 (ets domain transcription factor)
chr5_-_141061777 0.26 ENST00000239440.4
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr1_+_19638788 0.25 ENST00000375155.3
ENST00000375153.3
ENST00000400548.2
PQLC2
PQ loop repeat containing 2
chr1_+_36621529 0.25 ENST00000316156.4
MAP7D1
MAP7 domain containing 1
chr17_-_59668550 0.25 ENST00000521764.1
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr17_-_27044903 0.25 ENST00000395245.3
RAB34
RAB34, member RAS oncogene family
chr4_+_123747834 0.25 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chr2_+_201980827 0.24 ENST00000309955.3
ENST00000443227.1
ENST00000341222.6
ENST00000355558.4
ENST00000340870.5
ENST00000341582.6
CFLAR
CASP8 and FADD-like apoptosis regulator
chr17_-_27044810 0.24 ENST00000395242.2
RAB34
RAB34, member RAS oncogene family
chr5_-_141061759 0.24 ENST00000508305.1
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr3_+_121311966 0.23 ENST00000338040.4
FBXO40
F-box protein 40
chr14_+_103801140 0.22 ENST00000561325.1
ENST00000392715.2
ENST00000559130.1
ENST00000559532.1
ENST00000558506.1
EIF5
eukaryotic translation initiation factor 5
chr11_+_64692143 0.22 ENST00000164133.2
ENST00000532850.1
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr14_-_23426322 0.21 ENST00000555367.1
HAUS4
HAUS augmin-like complex, subunit 4
chr21_+_30671690 0.21 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr14_-_23426270 0.20 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4
HAUS augmin-like complex, subunit 4
chr12_-_76478686 0.20 ENST00000261182.8
NAP1L1
nucleosome assembly protein 1-like 1
chr10_-_23003460 0.20 ENST00000376573.4
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr6_+_31082603 0.20 ENST00000259881.9
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr10_+_86088381 0.20 ENST00000224756.8
ENST00000372088.2
CCSER2
coiled-coil serine-rich protein 2
chr12_-_719573 0.19 ENST00000397265.3
NINJ2
ninjurin 2
chr2_+_220144052 0.19 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr14_-_23426337 0.19 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS4
HAUS augmin-like complex, subunit 4
chr12_+_56732658 0.18 ENST00000228534.4
IL23A
interleukin 23, alpha subunit p19
chr12_-_53343602 0.17 ENST00000546897.1
ENST00000552551.1
KRT8
keratin 8
chr19_+_13842559 0.17 ENST00000586600.1
CCDC130
coiled-coil domain containing 130
chr11_+_59522837 0.16 ENST00000437946.2
STX3
syntaxin 3
chr3_+_191046810 0.16 ENST00000392455.3
ENST00000392456.3
CCDC50
coiled-coil domain containing 50
chr17_+_75315534 0.16 ENST00000590294.1
ENST00000329047.8
SEPT9
septin 9
chr1_+_36554470 0.16 ENST00000373178.4
ADPRHL2
ADP-ribosylhydrolase like 2
chr8_+_24771265 0.15 ENST00000518131.1
ENST00000437366.2
NEFM
neurofilament, medium polypeptide
chrX_-_154493791 0.15 ENST00000369454.3
RAB39B
RAB39B, member RAS oncogene family
chr5_-_75919253 0.15 ENST00000296641.4
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr10_+_86088337 0.15 ENST00000359979.4
CCSER2
coiled-coil serine-rich protein 2
chr4_-_146019693 0.15 ENST00000514390.1
ANAPC10
anaphase promoting complex subunit 10
chr22_+_23063100 0.14 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr3_+_19988885 0.14 ENST00000422242.1
RAB5A
RAB5A, member RAS oncogene family
chr18_+_32290218 0.14 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA
dystrobrevin, alpha
chr17_+_25799008 0.14 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chr7_-_35734730 0.13 ENST00000396081.1
ENST00000311350.3
HERPUD2
HERPUD family member 2
chr17_+_79650962 0.12 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chrX_-_48901012 0.12 ENST00000315869.7
TFE3
transcription factor binding to IGHM enhancer 3
chr5_+_141016969 0.12 ENST00000518856.1
RELL2
RELT-like 2
chr21_+_30671189 0.12 ENST00000286800.3
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr11_-_64013663 0.12 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr3_+_69134124 0.12 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr3_+_57094469 0.12 ENST00000334325.1
SPATA12
spermatogenesis associated 12
chr17_+_74733744 0.12 ENST00000586689.1
ENST00000587661.1
ENST00000593181.1
ENST00000336509.4
ENST00000355954.3
MFSD11
major facilitator superfamily domain containing 11
chr2_+_87754989 0.11 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152
long intergenic non-protein coding RNA 152
chr2_+_87754887 0.11 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
LINC00152
long intergenic non-protein coding RNA 152
chr6_+_56819895 0.10 ENST00000370748.3
BEND6
BEN domain containing 6
chr2_+_87755054 0.09 ENST00000423846.1
LINC00152
long intergenic non-protein coding RNA 152
chr6_+_292051 0.09 ENST00000344450.5
DUSP22
dual specificity phosphatase 22
chr14_+_69726656 0.09 ENST00000337827.4
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr1_+_155107820 0.09 ENST00000484157.1
SLC50A1
solute carrier family 50 (sugar efflux transporter), member 1
chr11_+_35639735 0.08 ENST00000317811.4
FJX1
four jointed box 1 (Drosophila)
chr17_+_47287749 0.08 ENST00000419580.2
ABI3
ABI family, member 3
chr1_-_52344471 0.08 ENST00000352171.7
ENST00000354831.7
NRD1
nardilysin (N-arginine dibasic convertase)
chr5_+_176237478 0.08 ENST00000329542.4
UNC5A
unc-5 homolog A (C. elegans)
chr6_-_38670897 0.08 ENST00000373365.4
GLO1
glyoxalase I
chr16_+_67571351 0.08 ENST00000428437.2
ENST00000569253.1
FAM65A
family with sequence similarity 65, member A
chr17_+_30677136 0.08 ENST00000394670.4
ENST00000321233.6
ENST00000394673.2
ENST00000341711.6
ENST00000579634.1
ENST00000580759.1
ENST00000342555.6
ENST00000577908.1
ENST00000394679.5
ENST00000582165.1
ZNF207
zinc finger protein 207
chr4_-_987164 0.07 ENST00000398520.2
SLC26A1
solute carrier family 26 (anion exchanger), member 1
chr11_+_5009424 0.06 ENST00000300762.1
MMP26
matrix metallopeptidase 26
chr12_-_102591604 0.06 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr18_+_61144160 0.06 ENST00000489441.1
ENST00000424602.1
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr16_+_74330673 0.06 ENST00000219313.4
ENST00000540379.1
ENST00000567958.1
ENST00000568615.2
PSMD7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr9_-_34662651 0.05 ENST00000259631.4
CCL27
chemokine (C-C motif) ligand 27
chr19_+_38794797 0.05 ENST00000301246.5
ENST00000588605.1
C19orf33
chromosome 19 open reading frame 33
chr1_-_115880852 0.05 ENST00000369512.2
NGF
nerve growth factor (beta polypeptide)

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.4 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.5 1.5 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4 1.8 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.4 1.6 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.4 0.8 GO:0002384 hepatic immune response(GO:0002384)
0.4 1.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 2.0 GO:0007296 vitellogenesis(GO:0007296)
0.3 2.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.3 8.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.3 1.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 1.3 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.3 2.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 5.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.8 GO:2001268 positive regulation of keratinocyte migration(GO:0051549) negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.2 1.9 GO:0051546 keratinocyte migration(GO:0051546)
0.2 0.5 GO:1903028 positive regulation of opsonization(GO:1903028)
0.2 0.8 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.8 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 3.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.4 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 1.5 GO:0044351 macropinocytosis(GO:0044351) phagosome-lysosome fusion(GO:0090385)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 1.1 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.5 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 2.8 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.7 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 1.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.5 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.4 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.4 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.2 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.4 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.5 GO:0015014 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:0032962 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.8 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.7 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 1.9 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.8 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.4 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 1.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 2.2 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.0 0.2 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 1.8 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 1.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 1.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 1.2 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0060512 prostate gland morphogenesis(GO:0060512)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.9 GO:0005610 laminin-5 complex(GO:0005610)
0.5 1.6 GO:0043259 laminin-2 complex(GO:0005607) laminin-10 complex(GO:0043259)
0.5 8.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.4 1.7 GO:0030934 anchoring collagen complex(GO:0030934)
0.3 1.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 4.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.4 GO:0032437 cuticular plate(GO:0032437)
0.1 0.6 GO:0070652 HAUS complex(GO:0070652)
0.1 0.5 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.6 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 2.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 1.7 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 2.6 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.0 GO:0031904 endosome lumen(GO:0031904)
0.0 2.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 1.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 4.6 GO:0030027 lamellipodium(GO:0030027)
0.0 2.6 GO:0001726 ruffle(GO:0001726)
0.0 1.7 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 8.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.8 2.4 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.5 1.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 3.6 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.3 1.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 0.8 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.2 1.1 GO:1990254 keratin filament binding(GO:1990254)
0.1 1.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.3 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.5 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 4.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.4 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 1.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 6.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 2.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 3.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:0016918 retinal binding(GO:0016918)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.0 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 9.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.8 ST STAT3 PATHWAY STAT3 Pathway
0.1 1.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 8.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 6.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 5.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 2.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.7 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins