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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for BCL6B

Z-value: 0.52

Motif logo

Transcription factors associated with BCL6B

Gene Symbol Gene ID Gene Info
ENSG00000161940.6 BCL6B transcription repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BCL6Bhg19_v2_chr17_+_6926339_69263770.038.7e-01Click!

Activity profile of BCL6B motif

Sorted Z-values of BCL6B motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_8975061 3.52 ENST00000299698.7
alpha-2-macroglobulin-like 1
chr4_+_69313145 2.24 ENST00000305363.4
transmembrane protease, serine 11E
chr2_-_216257849 2.02 ENST00000456923.1
fibronectin 1
chr8_-_91095099 1.63 ENST00000265431.3
calbindin 1, 28kDa
chr2_-_31361543 1.33 ENST00000349752.5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr19_+_11200038 1.29 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
low density lipoprotein receptor
chr1_-_153521597 1.20 ENST00000368712.1
S100 calcium binding protein A3
chr19_+_44037546 1.17 ENST00000601282.1
zinc finger protein 575
chr1_+_84609944 1.07 ENST00000370685.3
protein kinase, cAMP-dependent, catalytic, beta
chr7_+_134464376 1.04 ENST00000454108.1
ENST00000361675.2
caldesmon 1
chr1_-_153521714 1.04 ENST00000368713.3
S100 calcium binding protein A3
chr7_+_134464414 1.02 ENST00000361901.2
caldesmon 1
chr20_+_58251716 0.88 ENST00000355648.4
phosphatase and actin regulator 3
chr12_-_10007448 0.87 ENST00000538152.1
C-type lectin domain family 2, member B
chrX_-_153775426 0.86 ENST00000393562.2
glucose-6-phosphate dehydrogenase
chr17_-_76183111 0.86 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
thymidine kinase 1, soluble
chr3_-_123512688 0.85 ENST00000475616.1
myosin light chain kinase
chr4_-_99578776 0.85 ENST00000515287.1
tetraspanin 5
chr15_+_40886199 0.83 ENST00000346991.5
ENST00000528975.1
ENST00000527044.1
cancer susceptibility candidate 5
chr4_-_99578789 0.83 ENST00000511651.1
ENST00000505184.1
tetraspanin 5
chr10_-_70287172 0.73 ENST00000539557.1
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr3_+_50649302 0.70 ENST00000446044.1
mitogen-activated protein kinase-activated protein kinase 3
chr12_-_120687948 0.64 ENST00000458477.2
paxillin
chr18_-_29340827 0.63 ENST00000269205.5
solute carrier family 25, member 52
chr2_-_188419078 0.63 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr11_+_18230685 0.62 ENST00000340135.3
ENST00000534640.1
Putative mitochondrial carrier protein LOC494141
chr1_-_193029192 0.61 ENST00000417752.1
ENST00000367452.4
ubiquitin carboxyl-terminal hydrolase L5
chr2_-_188419200 0.60 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr19_-_13227534 0.59 ENST00000588229.1
ENST00000357720.4
tRNA methyltransferase 1 homolog (S. cerevisiae)
chr19_+_45147098 0.58 ENST00000425690.3
ENST00000344956.4
ENST00000403059.4
poliovirus receptor
chr19_-_13227463 0.56 ENST00000437766.1
ENST00000221504.8
tRNA methyltransferase 1 homolog (S. cerevisiae)
chr3_+_156799587 0.55 ENST00000469196.1
RP11-6F2.5
chr3_+_102153859 0.55 ENST00000306176.1
ENST00000466937.1
zona pellucida-like domain containing 1
chr15_-_64673665 0.55 ENST00000300035.4
KIAA0101
chr19_-_4831701 0.54 ENST00000248244.5
toll-like receptor adaptor molecule 1
chr12_-_123187890 0.54 ENST00000328880.5
hydroxycarboxylic acid receptor 2
chr2_+_143635067 0.53 ENST00000264170.4
kynureninase
chr12_-_123201337 0.52 ENST00000528880.2
hydroxycarboxylic acid receptor 3
chr19_+_45147313 0.51 ENST00000406449.4
poliovirus receptor
chr6_+_35995552 0.49 ENST00000468133.1
mitogen-activated protein kinase 14
chr17_-_9694614 0.49 ENST00000330255.5
ENST00000571134.1
dehydrogenase/reductase (SDR family) member 7C
chr12_+_93096619 0.48 ENST00000397833.3
chromosome 12 open reading frame 74
chr2_-_69098566 0.48 ENST00000295379.1
bone morphogenetic protein 10
chr6_+_42584847 0.48 ENST00000372883.3
ubiquitin protein ligase E3 component n-recognin 2
chr3_-_123603137 0.47 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
myosin light chain kinase
chr12_+_93964746 0.47 ENST00000536696.2
suppressor of cytokine signaling 2
chr17_+_4853442 0.47 ENST00000522301.1
enolase 3 (beta, muscle)
chr1_+_209878182 0.46 ENST00000367027.3
hydroxysteroid (11-beta) dehydrogenase 1
chr17_-_48474828 0.45 ENST00000576448.1
ENST00000225972.7
leucine rich repeat containing 59
chr5_+_72251793 0.44 ENST00000430046.2
ENST00000341845.6
FCH domain only 2
chr2_+_143635222 0.44 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
kynureninase
chr4_-_153303658 0.43 ENST00000296555.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr12_+_104324112 0.42 ENST00000299767.5
heat shock protein 90kDa beta (Grp94), member 1
chr15_-_75871589 0.41 ENST00000306726.2
protein tyrosine phosphatase, non-receptor type 9
chr1_-_108735440 0.39 ENST00000370041.4
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr11_-_18258342 0.37 ENST00000278222.4
serum amyloid A4, constitutive
chr6_+_35995531 0.37 ENST00000229794.4
mitogen-activated protein kinase 14
chr5_+_72251857 0.36 ENST00000507345.2
ENST00000512348.1
ENST00000287761.6
FCH domain only 2
chr1_-_41131326 0.36 ENST00000372684.3
regulating synaptic membrane exocytosis 3
chr6_+_35995488 0.35 ENST00000229795.3
mitogen-activated protein kinase 14
chr6_+_44194762 0.33 ENST00000371708.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr6_-_108145499 0.32 ENST00000369020.3
ENST00000369022.2
sex comb on midleg-like 4 (Drosophila)
chr2_-_55237484 0.30 ENST00000394609.2
reticulon 4
chr11_+_120081475 0.30 ENST00000328965.4
OAF homolog (Drosophila)
chr9_+_139702363 0.30 ENST00000371663.4
ENST00000371671.4
ENST00000311502.7
RAB, member RAS oncogene family-like 6
chr7_+_28452130 0.30 ENST00000357727.2
cAMP responsive element binding protein 5
chr1_+_235530675 0.29 ENST00000366601.3
ENST00000406207.1
ENST00000543662.1
tubulin folding cofactor E
chr10_+_11207438 0.29 ENST00000609692.1
ENST00000354897.3
CUGBP, Elav-like family member 2
chr3_-_50649192 0.29 ENST00000443053.2
ENST00000348721.3
cytokine inducible SH2-containing protein
chr6_-_155776966 0.28 ENST00000159060.2
NADPH oxidase 3
chr13_-_73356234 0.28 ENST00000545453.1
DIS3 mitotic control homolog (S. cerevisiae)
chr3_+_158787041 0.28 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1 readthrough
chr2_+_239756671 0.27 ENST00000448943.2
twist family bHLH transcription factor 2
chr13_-_33112956 0.26 ENST00000505213.1
NEDD4 binding protein 2-like 2
chrX_+_78426469 0.26 ENST00000276077.1
G protein-coupled receptor 174
chrX_+_79675965 0.25 ENST00000308293.5
family with sequence similarity 46, member D
chr14_+_31028348 0.25 ENST00000550944.1
ENST00000438909.2
ENST00000553504.1
G2/M-phase specific E3 ubiquitin protein ligase
chr12_-_122238913 0.24 ENST00000537157.1
AC084018.1
chrX_-_30993201 0.23 ENST00000288422.2
ENST00000378932.2
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr9_+_88556036 0.23 ENST00000361671.5
ENST00000416045.1
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr12_-_12674032 0.23 ENST00000298573.4
dual specificity phosphatase 16
chr2_+_87755054 0.23 ENST00000423846.1
long intergenic non-protein coding RNA 152
chr8_+_50824233 0.23 ENST00000522124.1
syntrophin, gamma 1
chr2_+_87754989 0.22 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
long intergenic non-protein coding RNA 152
chr11_+_113779704 0.22 ENST00000537778.1
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
chr16_-_75498308 0.22 ENST00000569540.1
transmembrane protein 170A
chr18_-_66382289 0.22 ENST00000443099.2
ENST00000562706.1
ENST00000544714.2
thioredoxin-related transmembrane protein 3
chr19_+_39786962 0.22 ENST00000333625.2
interferon, lambda 1
chr2_+_87754887 0.22 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
long intergenic non-protein coding RNA 152
chr13_-_33112899 0.21 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
NEDD4 binding protein 2-like 2
chrX_-_100604184 0.20 ENST00000372902.3
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr14_-_30396948 0.19 ENST00000331968.5
protein kinase D1
chr12_+_20522179 0.19 ENST00000359062.3
phosphodiesterase 3A, cGMP-inhibited
chr4_+_70796784 0.19 ENST00000246891.4
ENST00000444405.3
casein alpha s1
chr10_-_73976884 0.19 ENST00000317126.4
ENST00000545550.1
activating signal cointegrator 1 complex subunit 1
chrX_+_139791917 0.19 ENST00000607004.1
ENST00000370535.3
long intergenic non-protein coding RNA 632
chr14_+_31028329 0.19 ENST00000206595.6
G2/M-phase specific E3 ubiquitin protein ligase
chr5_-_172198190 0.18 ENST00000239223.3
dual specificity phosphatase 1
chr9_-_86322831 0.18 ENST00000257468.7
ubiquilin 1
chr13_+_53191605 0.18 ENST00000342657.3
ENST00000398039.1
heterogeneous nuclear ribonucleoprotein A1-like 2
chr17_+_38497640 0.16 ENST00000394086.3
retinoic acid receptor, alpha
chr17_-_42908155 0.16 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
gap junction protein, gamma 1, 45kDa
chr2_-_89266286 0.16 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr8_-_130799134 0.16 ENST00000276708.4
gasdermin C
chr4_-_155511887 0.16 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chrX_-_134936550 0.15 ENST00000494421.1
cancer/testis antigen family 45, member A4
chr15_-_49913126 0.15 ENST00000561064.1
ENST00000299338.6
family with sequence similarity 227, member B
chr8_-_107782463 0.14 ENST00000311955.3
actin-binding Rho activating protein
chr6_+_31588478 0.14 ENST00000376007.4
ENST00000376033.2
proline-rich coiled-coil 2A
chr8_+_104427581 0.14 ENST00000521716.1
ENST00000521971.1
ENST00000519682.1
DDB1 and CUL4 associated factor 13
chr11_+_58874701 0.13 ENST00000529618.1
ENST00000534403.1
ENST00000343597.3
family with sequence similarity 111, member B
chr6_+_125540951 0.13 ENST00000524679.1
tumor protein D52-like 1
chr6_-_136788001 0.13 ENST00000544465.1
microtubule-associated protein 7
chr10_-_73976025 0.13 ENST00000342444.4
ENST00000533958.1
ENST00000527593.1
ENST00000394915.3
ENST00000530461.1
ENST00000317168.6
ENST00000524829.1
activating signal cointegrator 1 complex subunit 1
chr3_+_44771088 0.13 ENST00000396048.2
zinc finger protein 501
chr17_-_42907564 0.13 ENST00000592524.1
gap junction protein, gamma 1, 45kDa
chr21_+_44394742 0.12 ENST00000432907.2
PBX/knotted 1 homeobox 1
chrX_+_134847370 0.12 ENST00000482795.1
cancer/testis antigen family 45, member A1
chr8_-_81787006 0.12 ENST00000327835.3
zinc finger protein 704
chr12_-_11002063 0.12 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
proline rich 4 (lacrimal)
chr5_-_145214893 0.12 ENST00000394450.2
PRELI domain containing 2
chr12_+_70132458 0.12 ENST00000247833.7
RAB3A interacting protein
chr17_-_54893250 0.11 ENST00000397862.2
chromosome 17 open reading frame 67
chrX_+_134847185 0.11 ENST00000370741.3
ENST00000497301.2
cancer/testis antigen family 45, member A1
chr12_+_16500037 0.11 ENST00000536371.1
ENST00000010404.2
microsomal glutathione S-transferase 1
chr8_-_141810634 0.11 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
protein tyrosine kinase 2
chr4_-_76957214 0.10 ENST00000306621.3
chemokine (C-X-C motif) ligand 11
chr6_-_29324054 0.10 ENST00000543825.1
olfactory receptor, family 5, subfamily V, member 1
chr22_-_50699701 0.10 ENST00000395780.1
mitogen-activated protein kinase 12
chr2_+_70121075 0.10 ENST00000409116.1
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr12_-_11175219 0.09 ENST00000390673.2
taste receptor, type 2, member 19
chrX_-_134936735 0.09 ENST00000487941.2
ENST00000434966.2
cancer/testis antigen family 45, member A4
chrX_-_134971059 0.09 ENST00000472834.1
cancer/testis antigen family 45, member A6
chr6_+_7541845 0.09 ENST00000418664.2
desmoplakin
chr5_+_54398463 0.08 ENST00000274306.6
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr1_+_221051699 0.08 ENST00000366903.6
H2.0-like homeobox
chr6_-_29343068 0.08 ENST00000396806.3
olfactory receptor, family 12, subfamily D, member 3
chr22_+_24990746 0.08 ENST00000456869.1
ENST00000411974.1
gamma-glutamyltransferase 1
chr1_-_76398077 0.08 ENST00000284142.6
ankyrin repeat and SOCS box containing 17
chr4_+_89378261 0.08 ENST00000264350.3
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr13_-_73356009 0.08 ENST00000377780.4
ENST00000377767.4
DIS3 mitotic control homolog (S. cerevisiae)
chr7_-_122840015 0.08 ENST00000194130.2
solute carrier family 13 (sodium/sulfate symporter), member 1
chr19_+_55128576 0.08 ENST00000396331.1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr7_-_29186008 0.08 ENST00000396276.3
ENST00000265394.5
carboxypeptidase, vitellogenic-like
chr17_+_34312621 0.08 ENST00000591669.1
Uncharacterized protein
chr16_-_67517716 0.08 ENST00000290953.2
agouti related protein homolog (mouse)
chr3_+_35682913 0.07 ENST00000449196.1
cAMP-regulated phosphoprotein, 21kDa
chr3_+_45017722 0.07 ENST00000265564.7
exosome component 7
chr5_+_140535577 0.07 ENST00000539533.1
Protocadherin-psi1; Uncharacterized protein
chr6_+_7541808 0.07 ENST00000379802.3
desmoplakin
chr12_+_70132632 0.07 ENST00000378815.6
ENST00000483530.2
ENST00000325555.9
RAB3A interacting protein
chr3_+_44690211 0.07 ENST00000396056.2
ENST00000432115.2
ENST00000415571.2
ENST00000399560.2
ENST00000296092.3
ENST00000542250.1
ENST00000453164.1
zinc finger protein 35
chr2_+_173686303 0.07 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr15_-_38519066 0.07 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
chr20_-_4229721 0.06 ENST00000379453.4
adrenoceptor alpha 1D
chr18_+_55018044 0.06 ENST00000324000.3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr19_-_7812446 0.06 ENST00000394173.4
ENST00000301357.8
CD209 molecule
chr3_+_46618727 0.06 ENST00000296145.5
teratocarcinoma-derived growth factor 1
chr14_-_94970559 0.06 ENST00000556881.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chrX_-_134971244 0.05 ENST00000491002.2
ENST00000448053.2
cancer/testis antigen family 45, member A6
chr3_-_64673289 0.05 ENST00000295903.4
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr11_+_64059464 0.05 ENST00000394525.2
potassium channel, subfamily K, member 4
chr1_+_158815588 0.05 ENST00000438394.1
myeloid cell nuclear differentiation antigen
chr11_+_58912240 0.05 ENST00000527629.1
ENST00000361723.3
ENST00000531408.1
family with sequence similarity 111, member A
chr11_+_18230727 0.05 ENST00000527059.1
Putative mitochondrial carrier protein LOC494141
chrX_+_153775821 0.04 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr21_+_17102311 0.04 ENST00000285679.6
ENST00000351097.5
ENST00000285681.2
ENST00000400183.2
ubiquitin specific peptidase 25
chr10_-_70287231 0.04 ENST00000609923.1
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr15_+_69854027 0.03 ENST00000498938.2
RP11-279F6.1
chr4_+_17616253 0.03 ENST00000237380.7
mediator complex subunit 28
chr12_-_43945724 0.03 ENST00000389420.3
ENST00000553158.1
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr6_-_32083106 0.03 ENST00000442721.1
tenascin XB
chr5_-_145214848 0.02 ENST00000505416.1
ENST00000334744.4
ENST00000358004.2
ENST00000511435.1
PRELI domain containing 2
chr2_-_175499294 0.02 ENST00000392547.2
WAS/WASL interacting protein family, member 1
chr1_+_111991474 0.02 ENST00000369722.3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr19_+_55235969 0.02 ENST00000402254.2
ENST00000538269.1
ENST00000541392.1
ENST00000291860.1
ENST00000396284.2
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
chr9_-_117880477 0.02 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
tenascin C
chr7_+_2636522 0.02 ENST00000423196.1
IQ motif containing E
chr5_+_140480083 0.01 ENST00000231130.2
protocadherin beta 3
chrX_-_139866723 0.01 ENST00000370532.2
cerebellar degeneration-related protein 1, 34kDa
chr12_+_16064106 0.01 ENST00000428559.2
deoxyribose-phosphate aldolase (putative)
chr14_-_21567009 0.01 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
zinc finger protein 219
chr20_+_56136136 0.00 ENST00000319441.4
ENST00000543666.1
phosphoenolpyruvate carboxykinase 1 (soluble)

Network of associatons between targets according to the STRING database.

First level regulatory network of BCL6B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.4 1.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.3 1.3 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.3 1.0 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.3 0.9 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2 1.2 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.2 0.9 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.2 1.6 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.2 1.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 1.1 GO:0097338 response to clozapine(GO:0097338)
0.1 1.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.4 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.5 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.5 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.4 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.3 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 0.4 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.5 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.3 GO:0015862 uridine transport(GO:0015862)
0.1 0.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.7 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.3 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 1.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.3 GO:0048840 otolith development(GO:0048840)
0.0 0.7 GO:0007172 signal complex assembly(GO:0007172)
0.0 1.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.6 GO:0048853 lateral ventricle development(GO:0021670) forebrain morphogenesis(GO:0048853)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.4 GO:0015866 ADP transport(GO:0015866)
0.0 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:2001202 negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.0 0.1 GO:0071046 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.0 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.2 2.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 2.1 GO:0030478 actin cap(GO:0030478)
0.1 0.2 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.5 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 2.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.6 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0005499 vitamin D binding(GO:0005499)
0.3 0.9 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.3 1.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3 0.9 GO:0004797 thymidine kinase activity(GO:0004797)
0.2 1.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2 1.0 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 0.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 1.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.2 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 2.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0015116 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.5 GO:0031433 telethonin binding(GO:0031433)
0.0 0.2 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.0 0.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 2.0 GO:0016504 peptidase activator activity(GO:0016504)
0.0 4.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.0 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID IGF1 PATHWAY IGF1 pathway
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 2.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 3.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 1.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.8 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis