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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for BHLHE22_BHLHA15_BHLHE23

Z-value: 0.69

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Transcription factors associated with BHLHE22_BHLHA15_BHLHE23

Gene Symbol Gene ID Gene Info
ENSG00000180828.1 basic helix-loop-helix family member e22
ENSG00000180535.3 basic helix-loop-helix family member a15
ENSG00000125533.4 basic helix-loop-helix family member e23

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BHLHE22hg19_v2_chr8_+_65492756_65492814-0.115.6e-01Click!

Activity profile of BHLHE22_BHLHA15_BHLHE23 motif

Sorted Z-values of BHLHE22_BHLHA15_BHLHE23 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_163148161 3.89 ENST00000337019.3
ENST00000366889.2
PARK2 co-regulated
chr1_+_95975672 3.82 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
chr1_+_104293028 3.62 ENST00000370079.3
amylase, alpha 1C (salivary)
chr15_-_65503801 2.98 ENST00000261883.4
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr1_+_244214577 2.83 ENST00000358704.4
zinc finger and BTB domain containing 18
chr5_-_111312622 2.11 ENST00000395634.3
neuronal regeneration related protein
chr3_-_121379739 2.09 ENST00000428394.2
ENST00000314583.3
hematopoietic cell-specific Lyn substrate 1
chr15_-_98417780 2.06 ENST00000503874.3
long intergenic non-protein coding RNA 923
chr1_+_47489240 1.93 ENST00000371901.3
cytochrome P450, family 4, subfamily X, polypeptide 1
chr6_+_135502501 1.64 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
v-myb avian myeloblastosis viral oncogene homolog
chr3_-_114477962 1.47 ENST00000471418.1
zinc finger and BTB domain containing 20
chr19_+_56368803 1.45 ENST00000587891.1
NLR family, pyrin domain containing 4
chr3_-_114477787 1.37 ENST00000464560.1
zinc finger and BTB domain containing 20
chr7_-_99573677 1.32 ENST00000292401.4
alpha-2-glycoprotein 1, zinc-binding
chr16_-_69385681 1.31 ENST00000288025.3
transmembrane emp24 protein transport domain containing 6
chr1_+_61330931 1.16 ENST00000371191.1
nuclear factor I/A
chr9_-_130635741 0.99 ENST00000223836.10
adenylate kinase 1
chr2_+_186603355 0.92 ENST00000343098.5
fibrous sheath interacting protein 2
chr14_-_107283278 0.89 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr4_+_160188889 0.82 ENST00000264431.4
Rap guanine nucleotide exchange factor (GEF) 2
chr4_-_70505358 0.81 ENST00000457664.2
ENST00000604629.1
ENST00000604021.1
UDP glucuronosyltransferase 2 family, polypeptide A2
chr11_+_120107344 0.70 ENST00000260264.4
POU class 2 homeobox 3
chr7_-_55930443 0.70 ENST00000388975.3
septin 14
chr7_-_38403077 0.70 ENST00000426402.2
T cell receptor gamma variable 2
chr3_-_197300194 0.68 ENST00000358186.2
ENST00000431056.1
3-hydroxybutyrate dehydrogenase, type 1
chr5_-_114632307 0.66 ENST00000506442.1
ENST00000379611.5
coiled-coil domain containing 112
chr8_+_67976593 0.55 ENST00000262210.5
ENST00000412460.1
centrosome and spindle pole associated protein 1
chr15_+_65843130 0.51 ENST00000569894.1
protein tyrosine phosphatase-like A domain containing 1
chr6_-_119031228 0.51 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
centrosomal protein 85kDa-like
chr4_-_74088800 0.49 ENST00000509867.2
ankyrin repeat domain 17
chr12_-_91573132 0.47 ENST00000550563.1
ENST00000546370.1
decorin
chr3_+_112930306 0.47 ENST00000495514.1
BOC cell adhesion associated, oncogene regulated
chr1_-_152131703 0.47 ENST00000316073.3
repetin
chr19_-_37019562 0.43 ENST00000523638.1
zinc finger protein 260
chr16_-_4896205 0.41 ENST00000589389.1
glyoxylate reductase 1 homolog (Arabidopsis)
chr13_+_28813645 0.40 ENST00000282391.5
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr18_-_52989525 0.39 ENST00000457482.3
transcription factor 4
chr3_-_131753830 0.38 ENST00000429747.1
copine IV
chr6_+_97010424 0.37 ENST00000541107.1
ENST00000450218.1
ENST00000326771.2
four and a half LIM domains 5
chr20_-_34117447 0.37 ENST00000246199.2
ENST00000424444.1
ENST00000374345.4
ENST00000444723.1
chromosome 20 open reading frame 173
chr10_-_48416849 0.35 ENST00000249598.1
growth differentiation factor 2
chr7_-_92855762 0.35 ENST00000453812.2
ENST00000394468.2
HEPACAM family member 2
chrX_+_105855160 0.34 ENST00000372544.2
ENST00000372548.4
chromosome X open reading frame 57
chr4_-_87028478 0.33 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr11_-_44972418 0.33 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
tumor protein p53 inducible protein 11
chr21_-_36421401 0.33 ENST00000486278.2
runt-related transcription factor 1
chr9_+_18474098 0.33 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
ADAMTS-like 1
chr1_-_186344802 0.31 ENST00000451586.1
translocated promoter region, nuclear basket protein
chr1_+_186344883 0.30 ENST00000367470.3
chromosome 1 open reading frame 27
chr19_+_18208603 0.30 ENST00000262811.6
microtubule associated serine/threonine kinase 3
chr15_-_55700522 0.29 ENST00000564092.1
ENST00000310958.6
cell cycle progression 1
chrX_-_13835147 0.29 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr11_-_44972476 0.28 ENST00000527685.1
ENST00000308212.5
tumor protein p53 inducible protein 11
chr8_-_38239732 0.27 ENST00000534155.1
ENST00000433384.2
ENST00000317025.8
ENST00000316985.3
Wolf-Hirschhorn syndrome candidate 1-like 1
chr19_-_54876558 0.27 ENST00000391742.2
ENST00000434277.2
leukocyte-associated immunoglobulin-like receptor 1
chrX_-_13835461 0.25 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr9_+_2158485 0.25 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_112930387 0.25 ENST00000485230.1
BOC cell adhesion associated, oncogene regulated
chr8_-_23315190 0.25 ENST00000356206.6
ENST00000358689.4
ENST00000417069.2
ectonucleoside triphosphate diphosphohydrolase 4
chr1_-_217250231 0.24 ENST00000493748.1
ENST00000463665.1
estrogen-related receptor gamma
chr9_+_2158443 0.24 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr13_+_49551020 0.24 ENST00000541916.1
fibronectin type III domain containing 3A
chr1_+_186344945 0.23 ENST00000419367.3
ENST00000287859.6
chromosome 1 open reading frame 27
chr4_+_25915896 0.23 ENST00000514384.1
small integral membrane protein 20
chr4_+_154178520 0.22 ENST00000433687.1
tripartite motif containing 2
chr1_+_159272111 0.21 ENST00000368114.1
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr15_-_55700457 0.21 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
cell cycle progression 1
chr16_-_52640834 0.20 ENST00000510238.3
cancer susceptibility candidate 16 (non-protein coding)
chr14_+_27342334 0.20 ENST00000548170.1
ENST00000552926.1
RP11-384J4.1
chr2_-_32490859 0.19 ENST00000404025.2
NLR family, CARD domain containing 4
chr2_-_32490801 0.19 ENST00000360906.5
ENST00000342905.6
NLR family, CARD domain containing 4
chr3_+_62304648 0.19 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
chromosome 3 open reading frame 14
chr5_+_173316341 0.19 ENST00000520867.1
ENST00000334035.5
cytoplasmic polyadenylation element binding protein 4
chr4_-_100575781 0.18 ENST00000511828.1
Protein LOC285556
chr10_+_51565188 0.16 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
nuclear receptor coactivator 4
chr9_+_108424738 0.16 ENST00000334077.3
T-cell acute lymphocytic leukemia 2
chr7_+_107531580 0.15 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
dihydrolipoamide dehydrogenase
chr1_-_205091115 0.15 ENST00000264515.6
ENST00000367164.1
retinoblastoma binding protein 5
chr10_+_51565108 0.15 ENST00000438493.1
ENST00000452682.1
nuclear receptor coactivator 4
chr3_+_113251143 0.14 ENST00000264852.4
ENST00000393830.3
SID1 transmembrane family, member 1
chr1_+_12524965 0.14 ENST00000471923.1
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr5_+_135496675 0.14 ENST00000507637.1
SMAD family member 5
chr3_+_46924829 0.13 ENST00000313049.5
parathyroid hormone 1 receptor
chr6_+_30539153 0.13 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ATP-binding cassette, sub-family F (GCN20), member 1
chr10_-_69597810 0.13 ENST00000483798.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr10_+_17794251 0.13 ENST00000377495.1
ENST00000338221.5
transmembrane protein 236
chr11_-_62359027 0.13 ENST00000494385.1
ENST00000308436.7
terminal uridylyl transferase 1, U6 snRNA-specific
chr14_+_69865401 0.13 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
solute carrier family 39, member 9
chr10_-_94257512 0.12 ENST00000371581.5
insulin-degrading enzyme
chrX_-_19817869 0.11 ENST00000379698.4
SH3-domain kinase binding protein 1
chrX_-_129402857 0.11 ENST00000447817.1
ENST00000370978.4
zinc finger protein 280C
chr14_-_51297837 0.10 ENST00000245441.5
ENST00000389868.3
ENST00000382041.3
ENST00000324330.9
ENST00000453196.1
ENST00000453401.2
ninein (GSK3B interacting protein)
chr9_+_12775011 0.10 ENST00000319264.3
leucine rich adaptor protein 1-like
chr2_-_183387430 0.10 ENST00000410103.1
phosphodiesterase 1A, calmodulin-dependent
chr3_-_108672742 0.09 ENST00000261047.3
guanylate cyclase activator 1C
chr5_+_156607829 0.09 ENST00000422843.3
IL2-inducible T-cell kinase
chr1_-_44818599 0.08 ENST00000537474.1
ERI1 exoribonuclease family member 3
chr3_-_18480260 0.08 ENST00000454909.2
SATB homeobox 1
chr12_+_50794730 0.08 ENST00000523389.1
ENST00000518561.1
ENST00000347328.5
ENST00000550260.1
La ribonucleoprotein domain family, member 4
chr9_+_125796806 0.07 ENST00000373642.1
G protein-coupled receptor 21
chr1_-_168464875 0.07 ENST00000422253.1
RP5-968D22.3
chr7_+_116502605 0.07 ENST00000458284.2
ENST00000490693.1
capping protein (actin filament) muscle Z-line, alpha 2
chr2_-_228582709 0.07 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
solute carrier family 19 (thiamine transporter), member 3
chr2_-_183387283 0.07 ENST00000435564.1
phosphodiesterase 1A, calmodulin-dependent
chr8_+_67782984 0.06 ENST00000396592.3
ENST00000422365.2
ENST00000492775.1
minichromosome maintenance domain containing 2
chr14_-_69864993 0.06 ENST00000555373.1
enhancer of rudimentary homolog (Drosophila)
chr12_-_75723805 0.06 ENST00000409799.1
ENST00000409445.3
calcyphosine 2
chr12_-_40013553 0.05 ENST00000308666.3
ATP-binding cassette, sub-family D (ALD), member 2
chr1_+_180897269 0.05 ENST00000367587.1
KIAA1614
chr15_-_55700216 0.05 ENST00000569205.1
cell cycle progression 1
chr12_-_91573316 0.05 ENST00000393155.1
decorin
chr6_-_169364429 0.04 ENST00000444586.1
RP3-495K2.3
chr3_+_137728842 0.04 ENST00000183605.5
claudin 18
chr4_-_141075330 0.04 ENST00000509479.2
mastermind-like 3 (Drosophila)
chr12_-_108714412 0.04 ENST00000412676.1
ENST00000550573.1
chemokine-like receptor 1
chr6_+_73076432 0.03 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr1_-_99470368 0.03 ENST00000263177.4
Lipid phosphate phosphatase-related protein type 5
chr7_-_97881429 0.03 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
tectonin beta-propeller repeat containing 1
chr2_+_181845843 0.03 ENST00000602710.1
ubiquitin-conjugating enzyme E2E 3
chr3_-_150264272 0.03 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
stress-associated endoplasmic reticulum protein 1
chr10_-_15902449 0.03 ENST00000277632.3
family with sequence similarity 188, member A
chr15_+_85144217 0.03 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
zinc finger and SCAN domain containing 2
chr3_-_108672609 0.02 ENST00000393963.3
ENST00000471108.1
guanylate cyclase activator 1C
chr11_-_107582775 0.02 ENST00000305991.2
sarcolipin
chr8_-_67976509 0.01 ENST00000518747.1
COP9 signalosome subunit 5
chr5_+_175299743 0.01 ENST00000502265.1
complexin 2
chr2_+_234637754 0.01 ENST00000482026.1
ENST00000609767.1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr1_-_99470558 0.01 ENST00000370188.3
Lipid phosphate phosphatase-related protein type 5
chr7_+_148287657 0.01 ENST00000307003.2
chromosome 7 open reading frame 33
chr7_+_116502527 0.01 ENST00000361183.3
capping protein (actin filament) muscle Z-line, alpha 2
chr7_-_112758665 0.01 ENST00000397764.3
long intergenic non-protein coding RNA 998
chr19_-_52227221 0.01 ENST00000222115.1
ENST00000540069.2
hyaluronan synthase 1
chrX_+_107334895 0.01 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
autophagy related 4A, cysteine peptidase
chr17_+_39846114 0.00 ENST00000586699.1
eukaryotic translation initiation factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of BHLHE22_BHLHA15_BHLHE23

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.3 0.8 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.3 3.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 2.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.5 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.3 GO:0045799 mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.2 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.2 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.1 0.1 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.5 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 2.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 1.1 GO:0072189 ureter development(GO:0072189)
0.0 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.4 GO:0070269 pyroptosis(GO:0070269)
0.0 0.7 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 1.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 4.6 GO:0007286 spermatid development(GO:0007286)
0.0 0.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.7 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.4 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 1.0 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 2.8 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 0.4 GO:0097503 sialylation(GO:0097503)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 1.4 GO:0032479 regulation of type I interferon production(GO:0032479)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.4 GO:0031251 PAN complex(GO:0031251)
0.1 0.2 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 1.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.3 GO:0044754 autolysosome(GO:0044754)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.7 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 0.7 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 0.8 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 1.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.4 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 3.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.9 GO:0070330 aromatase activity(GO:0070330)
0.1 0.4 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 1.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.2 GO:0019863 immunoglobulin receptor activity(GO:0019763) IgE binding(GO:0019863)
0.0 0.1 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 2.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes