Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for CACAGUG
Z-value: 0.58
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miRNA associated with seed CACAGUG
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_-_7921090 Show fit | 1.93 |
ENST00000378789.3
|
hydroxyacid oxidase (glycolate oxidase) 1 |
|
| chr4_-_107957454 Show fit | 1.00 |
ENST00000285311.3
|
dickkopf WNT signaling pathway inhibitor 2 |
|
| chr20_-_41818373 Show fit | 0.89 |
ENST00000373187.1
ENST00000356100.2 ENST00000373184.1 ENST00000373190.1 |
protein tyrosine phosphatase, receptor type, T |
|
| chr20_-_50419055 Show fit | 0.84 |
ENST00000217086.4
|
spalt-like transcription factor 4 |
|
| chr5_-_157002775 Show fit | 0.80 |
ENST00000257527.4
|
ADAM metallopeptidase domain 19 |
|
| chr11_-_123525289 Show fit | 0.78 |
ENST00000392770.2
ENST00000299333.3 ENST00000530277.1 |
sodium channel, voltage-gated, type III, beta subunit |
|
| chrX_+_78426469 Show fit | 0.75 |
ENST00000276077.1
|
G protein-coupled receptor 174 |
|
| chr4_+_5053162 Show fit | 0.67 |
ENST00000282908.5
|
serine/threonine kinase 32B |
|
| chr16_+_66878814 Show fit | 0.62 |
ENST00000394069.3
|
carbonic anhydrase VII |
|
| chr2_+_7057523 Show fit | 0.54 |
ENST00000320892.6
|
ring finger protein 144A |
Network of associatons between targets according to the STRING database.
First level regulatory network of CACAGUG
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.9 | GO:0009441 | glycolate metabolic process(GO:0009441) |
| 0.1 | 1.0 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.1 | 0.8 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 0.0 | 0.8 | GO:0006509 | membrane protein ectodomain proteolysis(GO:0006509) |
| 0.0 | 0.8 | GO:0043029 | T cell homeostasis(GO:0043029) |
| 0.1 | 0.7 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.1 | 0.6 | GO:0032849 | positive regulation of cellular pH reduction(GO:0032849) |
| 0.0 | 0.6 | GO:0090141 | positive regulation of mitochondrial fission(GO:0090141) |
| 0.2 | 0.5 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
| 0.0 | 0.5 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 1.0 | GO:0030315 | T-tubule(GO:0030315) |
| 0.1 | 0.8 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 0.0 | 0.7 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.1 | 0.5 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.1 | 0.4 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.0 | 0.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.3 | GO:0031415 | NatA complex(GO:0031415) |
| 0.0 | 0.3 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.0 | 0.3 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 1.9 | GO:0016899 | oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899) |
| 0.1 | 1.2 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.0 | 1.1 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 0.9 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.1 | 0.8 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.0 | 0.7 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
| 0.0 | 0.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 0.5 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.1 | 0.5 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
| 0.0 | 0.5 | GO:0030955 | potassium ion binding(GO:0030955) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.8 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 0.6 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.4 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 0.4 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.4 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 0.2 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.2 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 0.8 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.7 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 0.7 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.7 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 0.6 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.0 | 0.6 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 0.5 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 0.4 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.4 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |