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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for CACAGUG

Z-value: 0.58

Motif logo

miRNA associated with seed CACAGUG

NamemiRBASE accession
MIMAT0000424
MIMAT0022844
MIMAT0018109

Activity profile of CACAGUG motif

Sorted Z-values of CACAGUG motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_7921090 1.93 ENST00000378789.3
hydroxyacid oxidase (glycolate oxidase) 1
chr4_-_107957454 1.00 ENST00000285311.3
dickkopf WNT signaling pathway inhibitor 2
chr20_-_41818373 0.89 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
protein tyrosine phosphatase, receptor type, T
chr20_-_50419055 0.84 ENST00000217086.4
spalt-like transcription factor 4
chr5_-_157002775 0.80 ENST00000257527.4
ADAM metallopeptidase domain 19
chr11_-_123525289 0.78 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
sodium channel, voltage-gated, type III, beta subunit
chrX_+_78426469 0.75 ENST00000276077.1
G protein-coupled receptor 174
chr4_+_5053162 0.67 ENST00000282908.5
serine/threonine kinase 32B
chr16_+_66878814 0.62 ENST00000394069.3
carbonic anhydrase VII
chr2_+_7057523 0.54 ENST00000320892.6
ring finger protein 144A
chr17_-_50237343 0.53 ENST00000575181.1
ENST00000570565.1
carbonic anhydrase X
chr15_+_29131103 0.53 ENST00000558402.1
ENST00000558330.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr18_+_49866496 0.52 ENST00000442544.2
deleted in colorectal carcinoma
chr17_-_53499310 0.50 ENST00000262065.3
monocyte to macrophage differentiation-associated
chr12_+_40787194 0.50 ENST00000425730.2
ENST00000454784.4
mucin 19, oligomeric
chr22_-_37099555 0.49 ENST00000300105.6
calcium channel, voltage-dependent, gamma subunit 2
chr14_-_59932044 0.48 ENST00000395116.1
G protein-coupled receptor 135
chr1_-_179198702 0.47 ENST00000502732.1
c-abl oncogene 2, non-receptor tyrosine kinase
chr12_+_3600356 0.46 ENST00000382622.3
protein arginine methyltransferase 8
chr15_-_82641706 0.46 ENST00000439287.4
golgin A6 family-like 10
chrX_+_64708615 0.46 ENST00000338957.4
ENST00000423889.3
zinc finger CCCH-type containing 12B
chr15_-_82939157 0.45 ENST00000559949.1
golgin A6 family-like 18
chr11_-_30038490 0.44 ENST00000328224.6
potassium voltage-gated channel, shaker-related subfamily, member 4
chr3_+_139654018 0.42 ENST00000458420.3
calsyntenin 2
chr9_+_116638562 0.42 ENST00000374126.5
ENST00000288466.7
zinc finger protein 618
chr3_+_11034403 0.41 ENST00000287766.4
ENST00000425938.1
solute carrier family 6 (neurotransmitter transporter), member 1
chr15_-_83018198 0.41 ENST00000557886.1
golgin A6 family-like 19
chr19_-_344786 0.41 ENST00000264819.4
mesoderm induction early response 1, family member 2
chr6_+_118228657 0.40 ENST00000360388.4
solute carrier family 35, member F1
chr3_+_36421826 0.40 ENST00000273183.3
SH3 and cysteine rich domain
chrX_-_54384425 0.39 ENST00000375169.3
ENST00000354646.2
WNK lysine deficient protein kinase 3
chr15_-_56209306 0.39 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr5_-_179780312 0.39 ENST00000253778.8
glutamine-fructose-6-phosphate transaminase 2
chr5_+_156887027 0.38 ENST00000435489.2
ENST00000311946.7
NIPA-like domain containing 4
chr7_+_6144514 0.38 ENST00000306177.5
ENST00000465073.2
ubiquitin specific peptidase 42
chr8_-_10697281 0.37 ENST00000524114.1
ENST00000553390.1
ENST00000554914.1
PIN2/TERF1 interacting, telomerase inhibitor 1
SRY (sex determining region Y)-box 7
Transcription factor SOX-7; Uncharacterized protein; cDNA FLJ58508, highly similar to Transcription factor SOX-7
chr19_+_19322758 0.36 ENST00000252575.6
neurocan
chr22_+_21271714 0.36 ENST00000354336.3
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr7_+_138916231 0.36 ENST00000473989.3
ENST00000288561.8
ubinuclein 2
chr9_+_118916082 0.35 ENST00000328252.3
pregnancy-associated plasma protein A, pappalysin 1
chr12_+_54943134 0.34 ENST00000243052.3
phosphodiesterase 1B, calmodulin-dependent
chrX_+_150151752 0.34 ENST00000325307.7
high mobility group box 3
chr4_+_115519577 0.34 ENST00000310836.6
UDP glycosyltransferase 8
chr14_-_53619816 0.33 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD domain containing 1
chr16_+_77822427 0.33 ENST00000302536.2
vesicle amine transport 1-like
chr5_-_1524015 0.33 ENST00000283415.3
lysophosphatidylcholine acyltransferase 1
chr16_-_89007491 0.33 ENST00000327483.5
ENST00000564416.1
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chrX_-_3631635 0.33 ENST00000262848.5
protein kinase, X-linked
chr14_-_30396948 0.32 ENST00000331968.5
protein kinase D1
chr8_+_1922024 0.32 ENST00000320248.3
kelch repeat and BTB (POZ) domain containing 11
chr21_-_44846999 0.32 ENST00000270162.6
salt-inducible kinase 1
chr17_+_1958388 0.32 ENST00000399849.3
hypermethylated in cancer 1
chr22_-_28197486 0.32 ENST00000302326.4
meningioma (disrupted in balanced translocation) 1
chr22_-_37823468 0.31 ENST00000402918.2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr10_+_70320413 0.31 ENST00000373644.4
tet methylcytosine dioxygenase 1
chr2_-_100721178 0.30 ENST00000409236.2
AF4/FMR2 family, member 3
chr20_-_60982330 0.29 ENST00000279101.5
Cdk5 and Abl enzyme substrate 2
chr16_-_4292071 0.29 ENST00000399609.3
sarcalumenin
chr21_+_33245548 0.29 ENST00000270112.2
hormonally up-regulated Neu-associated kinase
chr1_+_54519242 0.28 ENST00000234827.1
transcription elongation factor A (SII) N-terminal and central domain containing 2
chrX_+_105066524 0.27 ENST00000243300.9
ENST00000428173.2
Nik related kinase
chr5_+_14664762 0.27 ENST00000284274.4
family with sequence similarity 105, member B
chr17_+_12569306 0.27 ENST00000425538.1
myocardin
chr12_+_113495492 0.27 ENST00000257600.3
deltex homolog 1 (Drosophila)
chr10_+_31608054 0.26 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
zinc finger E-box binding homeobox 1
chr19_+_19496624 0.26 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
GATA zinc finger domain containing 2A
chr7_+_24612935 0.26 ENST00000222644.5
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr16_-_4588822 0.25 ENST00000564828.1
cell death-inducing p53 target 1
chr8_-_81787006 0.25 ENST00000327835.3
zinc finger protein 704
chr2_-_25142708 0.25 ENST00000260600.5
ENST00000435135.1
adenylate cyclase 3
chr12_+_79258547 0.25 ENST00000457153.2
synaptotagmin I
chr19_+_51815102 0.25 ENST00000270642.8
IgLON family member 5
chr8_-_8751068 0.25 ENST00000276282.6
malignant fibrous histiocytoma amplified sequence 1
chr5_-_139726181 0.25 ENST00000507104.1
ENST00000230990.6
heparin-binding EGF-like growth factor
chr19_+_41222998 0.24 ENST00000263370.2
inositol-trisphosphate 3-kinase C
chr1_+_76540386 0.24 ENST00000328299.3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr19_-_7293942 0.24 ENST00000341500.5
ENST00000302850.5
insulin receptor
chr15_+_73344791 0.24 ENST00000261908.6
neogenin 1
chr19_+_1286097 0.23 ENST00000215368.2
ephrin-A2
chr2_+_192542850 0.23 ENST00000410026.2
nucleic acid binding protein 1
chr9_+_112403088 0.22 ENST00000448454.2
paralemmin 2
chr15_+_54305101 0.22 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
unc-13 homolog C (C. elegans)
chr4_-_174451370 0.22 ENST00000359562.4
heart and neural crest derivatives expressed 2
chrX_+_16804544 0.22 ENST00000380122.5
ENST00000398155.4
taxilin gamma
chr12_+_54422142 0.22 ENST00000243108.4
homeobox C6
chr2_-_227664474 0.22 ENST00000305123.5
insulin receptor substrate 1
chr2_+_155554797 0.21 ENST00000295101.2
potassium inwardly-rectifying channel, subfamily J, member 3
chr18_+_19749386 0.21 ENST00000269216.3
GATA binding protein 6
chr2_+_30454390 0.21 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
limb bud and heart development
chr4_-_177713788 0.21 ENST00000280193.2
vascular endothelial growth factor C
chr1_+_215256467 0.21 ENST00000391894.2
ENST00000444842.2
potassium channel, subfamily K, member 2
chrX_-_25034065 0.21 ENST00000379044.4
aristaless related homeobox
chrX_-_80065146 0.21 ENST00000373275.4
bromodomain and WD repeat domain containing 3
chr7_-_31380502 0.21 ENST00000297142.3
neuronal differentiation 6
chrX_+_49687216 0.21 ENST00000376088.3
chloride channel, voltage-sensitive 5
chr14_+_72399833 0.21 ENST00000553530.1
ENST00000556437.1
regulator of G-protein signaling 6
chr11_+_14665263 0.21 ENST00000282096.4
phosphodiesterase 3B, cGMP-inhibited
chr4_+_140222609 0.20 ENST00000296543.5
ENST00000398947.1
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr17_-_46692287 0.20 ENST00000239144.4
homeobox B8
chr3_-_24536253 0.20 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
thyroid hormone receptor, beta
chr22_-_39239987 0.20 ENST00000333039.2
neuronal pentraxin receptor
chr13_+_113622810 0.20 ENST00000397030.1
MCF.2 cell line derived transforming sequence-like
chr12_+_103981044 0.20 ENST00000388887.2
stabilin 2
chr18_+_54318616 0.20 ENST00000254442.3
WD repeat domain 7
chr17_+_47865917 0.20 ENST00000259021.4
ENST00000454930.2
ENST00000509773.1
ENST00000510819.1
ENST00000424009.2
K(lysine) acetyltransferase 7
chr7_+_21467642 0.19 ENST00000222584.3
ENST00000432066.2
Sp4 transcription factor
chr17_-_62658186 0.19 ENST00000262435.9
SMAD specific E3 ubiquitin protein ligase 2
chr14_+_56585048 0.19 ENST00000267460.4
pellino E3 ubiquitin protein ligase family member 2
chr1_-_154474589 0.19 ENST00000304760.2
Src homology 2 domain containing E
chr2_-_119605253 0.19 ENST00000295206.6
engrailed homeobox 1
chr2_-_40679186 0.19 ENST00000406785.2
solute carrier family 8 (sodium/calcium exchanger), member 1
chr6_-_46293378 0.19 ENST00000330430.6
regulator of calcineurin 2
chr5_-_132299313 0.19 ENST00000265343.5
AF4/FMR2 family, member 4
chr3_-_39195037 0.18 ENST00000273153.5
cysteine-serine-rich nuclear protein 1
chr1_+_203274639 0.18 ENST00000290551.4
BTG family, member 2
chr2_-_54087066 0.18 ENST00000394705.2
ENST00000352846.3
ENST00000406625.2
G protein-coupled receptor 75
GPR75-ASB3 readthrough
Ankyrin repeat and SOCS box protein 3
chr9_-_23821273 0.18 ENST00000380110.4
ELAV like neuron-specific RNA binding protein 2
chr13_-_103053946 0.18 ENST00000376131.4
fibroblast growth factor 14
chr10_-_71930222 0.18 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1 homolog A (S. cerevisiae)
chr3_+_122785895 0.18 ENST00000316218.7
protein disulfide isomerase family A, member 5
chr22_+_39898325 0.18 ENST00000325301.2
ENST00000404569.1
mitochondrial elongation factor 1
chr5_-_111754948 0.17 ENST00000261486.5
erythrocyte membrane protein band 4.1 like 4A
chr5_+_152870106 0.17 ENST00000285900.5
glutamate receptor, ionotropic, AMPA 1
chr12_+_56137064 0.17 ENST00000257868.5
ENST00000546799.1
growth differentiation factor 11
chr3_-_21792838 0.17 ENST00000281523.2
zinc finger protein 385D
chr5_+_65018017 0.17 ENST00000380985.5
ENST00000502464.1
neurolysin (metallopeptidase M3 family)
chr12_-_31744031 0.17 ENST00000389082.5
DENN/MADD domain containing 5B
chr1_+_39456895 0.17 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
akirin 1
chr2_-_24583168 0.17 ENST00000361999.3
intersectin 2
chr17_-_7232585 0.17 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
neuralized E3 ubiquitin protein ligase 4
chr21_-_28338732 0.17 ENST00000284987.5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chrX_+_14547632 0.17 ENST00000218075.4
glycine receptor, alpha 2
chr1_+_36396677 0.16 ENST00000373191.4
ENST00000397828.2
argonaute RISC catalytic component 3
chr11_-_18765389 0.16 ENST00000477854.1
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr14_+_101193164 0.16 ENST00000341267.4
delta-like 1 homolog (Drosophila)
chr9_-_140196703 0.16 ENST00000356628.2
NOTCH-regulated ankyrin repeat protein
chr9_+_116917807 0.16 ENST00000356083.3
collagen, type XXVII, alpha 1
chr4_+_113970772 0.16 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ankyrin 2, neuronal
chr5_-_59995921 0.16 ENST00000453022.2
ENST00000545085.1
ENST00000265036.5
DEP domain containing 1B
chr1_+_26737253 0.16 ENST00000326279.6
lin-28 homolog A (C. elegans)
chr19_+_50094866 0.16 ENST00000418929.2
proline rich 12
chr20_+_10199468 0.16 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr1_-_149889382 0.16 ENST00000369145.1
ENST00000369146.3
synaptic vesicle glycoprotein 2A
chr12_-_77459306 0.16 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F transcription factor 7
chr6_-_119399895 0.16 ENST00000338891.7
family with sequence similarity 184, member A
chr2_+_158114051 0.16 ENST00000259056.4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr6_+_136172820 0.15 ENST00000308191.6
phosphodiesterase 7B
chr5_+_143584814 0.15 ENST00000507359.3
potassium channel tetramerization domain containing 16
chr16_-_25269134 0.15 ENST00000328086.7
zinc finger with KRAB and SCAN domains 2
chr12_+_70760056 0.15 ENST00000258111.4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr1_-_47697387 0.15 ENST00000371884.2
T-cell acute lymphocytic leukemia 1
chr21_-_39288743 0.15 ENST00000609713.1
potassium inwardly-rectifying channel, subfamily J, member 6
chr6_-_107436473 0.15 ENST00000369042.1
BEN domain containing 3
chrX_-_129402857 0.15 ENST00000447817.1
ENST00000370978.4
zinc finger protein 280C
chr10_+_127408263 0.15 ENST00000337623.3
erythroid differentiation regulatory factor 1
chr4_-_139163491 0.14 ENST00000280612.5
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr9_-_130742792 0.14 ENST00000373095.1
family with sequence similarity 102, member A
chr13_-_107187462 0.14 ENST00000245323.4
ephrin-B2
chrX_+_37430822 0.14 ENST00000378621.3
ENST00000378619.3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr9_+_129376722 0.14 ENST00000526117.1
ENST00000373474.4
ENST00000355497.5
ENST00000425646.2
ENST00000561065.1
LIM homeobox transcription factor 1, beta
chr14_+_103243813 0.14 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TNF receptor-associated factor 3
chr5_+_132149017 0.14 ENST00000378693.2
sosondowah ankyrin repeat domain family member A
chr11_-_45687128 0.14 ENST00000308064.2
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr11_+_12695944 0.14 ENST00000361905.4
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr7_-_30066233 0.14 ENST00000222803.5
FK506 binding protein 14, 22 kDa
chr3_-_178790057 0.14 ENST00000311417.2
zinc finger, matrin-type 3
chr4_+_56815102 0.14 ENST00000257287.4
centrosomal protein 135kDa
chr11_+_120081475 0.14 ENST00000328965.4
OAF homolog (Drosophila)
chr17_-_8534067 0.14 ENST00000360416.3
ENST00000269243.4
myosin, heavy chain 10, non-muscle
chr3_-_87040233 0.13 ENST00000398399.2
vestigial like 3 (Drosophila)
chr19_+_15218180 0.13 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr13_+_52158610 0.13 ENST00000298125.5
WD repeat and FYVE domain containing 2
chr19_+_38397839 0.13 ENST00000222345.6
signal-induced proliferation-associated 1 like 3
chr5_+_138678131 0.13 ENST00000394795.2
ENST00000510080.1
poly(A) binding protein interacting protein 2
chr3_+_119187785 0.13 ENST00000295588.4
ENST00000476573.1
protein O-glucosyltransferase 1
chr12_-_54813229 0.13 ENST00000293379.4
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_+_70876891 0.13 ENST00000411986.2
cystathionase (cystathionine gamma-lyase)
chr12_-_123450986 0.13 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr17_+_27717415 0.13 ENST00000583121.1
ENST00000261716.3
TAO kinase 1
chr1_+_117452669 0.13 ENST00000393203.2
prostaglandin F2 receptor inhibitor
chr9_-_127905736 0.13 ENST00000336505.6
ENST00000373549.4
suppressor of cancer cell invasion
chr7_-_27213893 0.12 ENST00000283921.4
homeobox A10
chr8_-_41166953 0.12 ENST00000220772.3
secreted frizzled-related protein 1
chr1_-_35395178 0.12 ENST00000373347.1
discs, large (Drosophila) homolog-associated protein 3
chr10_-_90712520 0.12 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr3_+_50649302 0.12 ENST00000446044.1
mitogen-activated protein kinase-activated protein kinase 3
chr4_-_13546632 0.12 ENST00000382438.5
NK3 homeobox 2
chr2_-_11606275 0.12 ENST00000381525.3
ENST00000362009.4
E2F transcription factor 6
chr12_+_32112340 0.12 ENST00000540924.1
ENST00000312561.4
KIAA1551
chr19_+_48898132 0.12 ENST00000263269.3
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr22_+_46067678 0.12 ENST00000381061.4
ENST00000252934.5
ataxin 10
chr11_-_74109422 0.12 ENST00000298198.4
phosphoglucomutase 2-like 1
chr3_-_171178157 0.12 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TRAF2 and NCK interacting kinase
chrX_+_142967173 0.12 ENST00000370494.1
ubiquitin-conjugating enzyme E2N-like
chr11_-_60674037 0.12 ENST00000541371.1
ENST00000227524.4
pre-mRNA processing factor 19
chr11_-_118661828 0.12 ENST00000264018.4
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr16_-_402639 0.11 ENST00000262320.3
axin 1
chrX_+_72783026 0.11 ENST00000373504.6
ENST00000373502.5
cysteine-rich hydrophobic domain 1
chr20_+_48599506 0.11 ENST00000244050.2
snail family zinc finger 1
chr17_+_47572647 0.11 ENST00000172229.3
nerve growth factor receptor

Network of associatons between targets according to the STRING database.

First level regulatory network of CACAGUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 0.5 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.7 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.8 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.6 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.1 0.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.3 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.4 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.1 0.4 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.3 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.3 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222)
0.1 0.3 GO:0008355 olfactory learning(GO:0008355)
0.1 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.4 GO:1904751 positive regulation of telomeric DNA binding(GO:1904744) positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.2 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.2 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.2 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.2 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 0.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 1.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.2 GO:1990535 transformation of host cell by virus(GO:0019087) neuron projection maintenance(GO:1990535)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.1 GO:0048320 axial mesoderm formation(GO:0048320)
0.1 0.2 GO:0044691 tooth eruption(GO:0044691)
0.1 0.2 GO:0036309 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.2 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.0 0.2 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.4 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.0 0.2 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.2 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.2 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.5 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.2 GO:0045746 regulation of Notch signaling pathway(GO:0008593) negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.0 GO:0060067 cervix development(GO:0060067)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.2 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.3 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.1 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.4 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.2 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.1 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.0 GO:0008306 associative learning(GO:0008306)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.6 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0090650 rRNA transport(GO:0051029) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0007497 posterior midgut development(GO:0007497)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.2 GO:0032525 regulation of somitogenesis(GO:0014807) somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.1 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.0 GO:0072240 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.0 0.8 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0002678 chronic inflammatory response to non-antigenic stimulus(GO:0002545) positive regulation of chronic inflammatory response(GO:0002678) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.3 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0 0.0 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.4 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.4 GO:0044305 calyx of Held(GO:0044305)
0.1 0.8 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.3 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 1.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.0 GO:0030315 T-tubule(GO:0030315)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.5 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.8 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.5 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.2 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.7 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.2 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.5 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 1.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.0 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus