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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for CDC5L

Z-value: 1.06

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Transcription factors associated with CDC5L

Gene Symbol Gene ID Gene Info
CDC5L
ENSG00000096401.7 cell division cycle 5 like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDC5Lhg19_v2_chr6_+_44355257_443553150.115.8e-01Click!

Activity profile of CDC5L motif

Sorted Z-values of CDC5L motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_16921601 7.82 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
AGR3
anterior gradient 3
chr6_-_32557610 6.77 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr16_+_80574854 5.13 ENST00000305904.6
ENST00000568035.1
DYNLRB2
dynein, light chain, roadblock-type 2
chr6_-_32498046 4.50 ENST00000374975.3
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr1_+_38022572 4.49 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chr5_+_94727048 4.08 ENST00000283357.5
FAM81B
family with sequence similarity 81, member B
chr5_-_35938674 3.73 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL
calcyphosine-like
chr1_+_38022513 3.68 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr6_+_131958436 3.56 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr4_-_100356844 3.43 ENST00000437033.2
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr6_-_33041378 3.29 ENST00000428995.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr17_+_45908974 3.29 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr19_-_9006766 3.09 ENST00000599436.1
MUC16
mucin 16, cell surface associated
chr10_+_115511213 3.03 ENST00000361048.1
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr11_+_73661364 2.88 ENST00000339764.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr12_+_20963647 2.80 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr12_+_20963632 2.74 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr13_+_50589390 2.69 ENST00000360473.4
ENST00000312942.1
KCNRG
potassium channel regulator
chr1_-_150738261 2.44 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr6_+_32709119 2.42 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr1_-_104238912 2.41 ENST00000330330.5
AMY1B
amylase, alpha 1B (salivary)
chr1_-_104239076 2.36 ENST00000370080.3
AMY1B
amylase, alpha 1B (salivary)
chr5_+_140227048 2.35 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr2_+_102721023 2.32 ENST00000409589.1
ENST00000409329.1
IL1R1
interleukin 1 receptor, type I
chr3_-_120365866 2.19 ENST00000475447.2
HGD
homogentisate 1,2-dioxygenase
chr3_+_160559931 2.17 ENST00000464260.1
ENST00000295839.9
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr4_-_70725856 2.15 ENST00000226444.3
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr5_+_140213815 2.06 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr12_+_21168630 2.03 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr2_-_190445499 1.96 ENST00000261024.2
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr6_-_165723088 1.82 ENST00000230301.8
C6orf118
chromosome 6 open reading frame 118
chr18_-_24765248 1.79 ENST00000580774.1
ENST00000284224.8
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr12_+_20968608 1.78 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr8_-_133637624 1.75 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr6_-_39197226 1.71 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr12_+_21207503 1.69 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr8_+_76452097 1.65 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr4_-_100356291 1.64 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr10_-_61495760 1.57 ENST00000395347.1
SLC16A9
solute carrier family 16, member 9
chr10_+_51549498 1.56 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chr5_+_140220769 1.53 ENST00000531613.1
ENST00000378123.3
PCDHA8
protocadherin alpha 8
chr10_+_118305435 1.51 ENST00000369221.2
PNLIP
pancreatic lipase
chr3_+_108321623 1.51 ENST00000497905.1
ENST00000463306.1
DZIP3
DAZ interacting zinc finger protein 3
chr7_+_116654935 1.50 ENST00000432298.1
ENST00000422922.1
ST7
suppression of tumorigenicity 7
chrX_+_36246735 1.48 ENST00000378653.3
CXorf30
chromosome X open reading frame 30
chr11_-_111944704 1.47 ENST00000532211.1
PIH1D2
PIH1 domain containing 2
chr1_+_144339738 1.46 ENST00000538264.1
AL592284.1
Protein LOC642441
chr1_+_59775752 1.46 ENST00000371212.1
FGGY
FGGY carbohydrate kinase domain containing
chr6_-_52705641 1.45 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr4_-_100356551 1.44 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr8_-_54436491 1.44 ENST00000426023.1
RP11-400K9.4
RP11-400K9.4
chr10_-_62493223 1.40 ENST00000373827.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_-_38806404 1.39 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1
toll-like receptor 1
chr5_+_140165876 1.38 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr4_+_41614909 1.37 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr1_+_156338993 1.35 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr10_-_69597915 1.34 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr13_-_86373536 1.34 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr11_-_111944895 1.31 ENST00000431456.1
ENST00000280350.4
ENST00000530641.1
PIH1D2
PIH1 domain containing 2
chr1_-_86848760 1.25 ENST00000460698.2
ODF2L
outer dense fiber of sperm tails 2-like
chr10_-_116286563 1.24 ENST00000369253.2
ABLIM1
actin binding LIM protein 1
chr6_+_32812568 1.21 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr21_+_33784670 1.21 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chrX_+_36254051 1.20 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr12_+_133757995 1.19 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
ZNF268
zinc finger protein 268
chr4_+_41614720 1.19 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr12_+_9980113 1.18 ENST00000537723.1
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr2_+_232573208 1.14 ENST00000409115.3
PTMA
prothymosin, alpha
chr11_-_85430163 1.13 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr14_-_21516590 1.12 ENST00000555026.1
NDRG2
NDRG family member 2
chr19_-_11545920 1.12 ENST00000356392.4
ENST00000591179.1
CCDC151
coiled-coil domain containing 151
chr5_+_140514782 1.10 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr4_-_141348999 1.07 ENST00000325617.5
CLGN
calmegin
chr5_+_140180635 1.02 ENST00000522353.2
ENST00000532566.2
PCDHA3
protocadherin alpha 3
chr5_-_61031495 1.01 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
CTD-2170G1.2
chr8_+_104831554 1.00 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr2_+_232573222 0.99 ENST00000341369.7
ENST00000409683.1
PTMA
prothymosin, alpha
chr2_-_222436988 0.98 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPHA4
EPH receptor A4
chr17_+_37856299 0.97 ENST00000269571.5
ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr19_-_49843539 0.97 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4
CTC-301O7.4
chr9_+_90112117 0.96 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr10_-_116444371 0.96 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr7_+_116593433 0.96 ENST00000323984.3
ENST00000393449.1
ST7
suppression of tumorigenicity 7
chr1_-_86043921 0.95 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr12_-_39734783 0.94 ENST00000552961.1
KIF21A
kinesin family member 21A
chr17_+_37856253 0.90 ENST00000540147.1
ENST00000584450.1
ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr5_-_179499108 0.89 ENST00000521389.1
RNF130
ring finger protein 130
chr14_-_106453155 0.89 ENST00000390594.2
IGHV1-2
immunoglobulin heavy variable 1-2
chr8_+_21911054 0.88 ENST00000519850.1
ENST00000381470.3
DMTN
dematin actin binding protein
chr5_-_179499086 0.88 ENST00000261947.4
RNF130
ring finger protein 130
chr11_-_85430088 0.85 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr17_+_37856214 0.85 ENST00000445658.2
ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr4_-_48082192 0.84 ENST00000507351.1
TXK
TXK tyrosine kinase
chr5_-_111093759 0.84 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr6_+_33422343 0.82 ENST00000395064.2
ZBTB9
zinc finger and BTB domain containing 9
chr22_+_29168652 0.81 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr10_-_69597810 0.80 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr10_+_96698406 0.80 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr5_+_139505520 0.79 ENST00000333305.3
IGIP
IgA-inducing protein
chr16_+_78056412 0.79 ENST00000299642.4
ENST00000575655.1
CLEC3A
C-type lectin domain family 3, member A
chr10_-_1246317 0.78 ENST00000381305.1
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr1_+_196621156 0.77 ENST00000359637.2
CFH
complement factor H
chr5_+_147691979 0.77 ENST00000274565.4
SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr12_+_133758115 0.77 ENST00000541009.2
ENST00000592241.1
ZNF268
zinc finger protein 268
chr17_+_7788104 0.77 ENST00000380358.4
CHD3
chromodomain helicase DNA binding protein 3
chr10_-_28623368 0.77 ENST00000441595.2
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr12_-_111358372 0.77 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr12_+_12223867 0.75 ENST00000308721.5
BCL2L14
BCL2-like 14 (apoptosis facilitator)
chr11_-_114466477 0.74 ENST00000375478.3
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr17_-_73775839 0.73 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B
H3 histone, family 3B (H3.3B)
chrX_+_35937843 0.73 ENST00000297866.5
CXorf22
chromosome X open reading frame 22
chr14_+_67291158 0.72 ENST00000555456.1
GPHN
gephyrin
chr13_-_41768654 0.71 ENST00000379483.3
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr1_-_198990166 0.71 ENST00000427439.1
RP11-16L9.3
RP11-16L9.3
chr3_-_155394099 0.70 ENST00000414191.1
PLCH1
phospholipase C, eta 1
chr3_-_197300194 0.69 ENST00000358186.2
ENST00000431056.1
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr4_+_37455536 0.65 ENST00000381980.4
ENST00000508175.1
C4orf19
chromosome 4 open reading frame 19
chr8_+_19171128 0.64 ENST00000265807.3
SH2D4A
SH2 domain containing 4A
chr11_+_124055923 0.64 ENST00000318666.6
OR10D3
olfactory receptor, family 10, subfamily D, member 3 (non-functional)
chr4_+_41540160 0.64 ENST00000503057.1
ENST00000511496.1
LIMCH1
LIM and calponin homology domains 1
chr3_-_127541194 0.64 ENST00000453507.2
MGLL
monoglyceride lipase
chr21_+_43619796 0.63 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr19_+_35939154 0.63 ENST00000599180.2
FFAR2
free fatty acid receptor 2
chr6_+_27791862 0.62 ENST00000355057.1
HIST1H4J
histone cluster 1, H4j
chr2_-_110962544 0.62 ENST00000355301.4
ENST00000445609.2
ENST00000417665.1
ENST00000418527.1
ENST00000316534.4
ENST00000393272.3
NPHP1
nephronophthisis 1 (juvenile)
chr15_-_43876702 0.61 ENST00000348806.6
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr1_+_174769006 0.61 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr20_-_18477862 0.61 ENST00000337227.4
RBBP9
retinoblastoma binding protein 9
chr16_+_4845379 0.61 ENST00000588606.1
ENST00000586005.1
SMIM22
small integral membrane protein 22
chrM_+_12331 0.60 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr12_+_55248289 0.60 ENST00000308796.6
MUCL1
mucin-like 1
chr8_+_99956759 0.60 ENST00000522510.1
ENST00000457907.2
OSR2
odd-skipped related transciption factor 2
chr4_+_170541660 0.59 ENST00000513761.1
ENST00000347613.4
CLCN3
chloride channel, voltage-sensitive 3
chr1_-_216978709 0.59 ENST00000360012.3
ESRRG
estrogen-related receptor gamma
chr9_-_115653176 0.58 ENST00000374228.4
SLC46A2
solute carrier family 46, member 2
chr1_+_166958346 0.58 ENST00000367872.4
MAEL
maelstrom spermatogenic transposon silencer
chr12_-_25150409 0.58 ENST00000549262.1
C12orf77
chromosome 12 open reading frame 77
chr4_-_69111401 0.58 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr4_-_87028478 0.58 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr3_+_171561127 0.57 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr10_+_106113515 0.57 ENST00000369704.3
ENST00000312902.5
CCDC147
coiled-coil domain containing 147
chr19_-_10697895 0.56 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chrX_-_131262048 0.56 ENST00000298542.4
FRMD7
FERM domain containing 7
chr16_+_57576584 0.56 ENST00000340339.4
GPR114
G protein-coupled receptor 114
chr10_+_111765562 0.56 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr6_-_76072719 0.55 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr12_+_80603233 0.55 ENST00000547103.1
ENST00000458043.2
OTOGL
otogelin-like
chr15_+_36338242 0.55 ENST00000560056.1
RP11-684B21.1
RP11-684B21.1
chr1_+_152635854 0.55 ENST00000368784.1
LCE2D
late cornified envelope 2D
chr17_-_35969409 0.54 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG
synergin, gamma
chr12_-_65146636 0.54 ENST00000418919.2
GNS
glucosamine (N-acetyl)-6-sulfatase
chr4_+_130017268 0.53 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33
chromosome 4 open reading frame 33
chr14_+_76452090 0.53 ENST00000314067.6
ENST00000238628.6
ENST00000556742.1
IFT43
intraflagellar transport 43 homolog (Chlamydomonas)
chrX_+_144908928 0.52 ENST00000408967.2
TMEM257
transmembrane protein 257
chr2_+_66662510 0.52 ENST00000272369.9
ENST00000407092.2
MEIS1
Meis homeobox 1
chr1_+_9599540 0.52 ENST00000302692.6
SLC25A33
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr21_-_43816052 0.51 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr6_-_49681235 0.50 ENST00000339139.4
CRISP2
cysteine-rich secretory protein 2
chr16_-_5116025 0.50 ENST00000472572.3
ENST00000315997.5
ENST00000422873.1
ENST00000350219.4
C16orf89
chromosome 16 open reading frame 89
chr2_-_160473114 0.50 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr1_-_89591749 0.50 ENST00000370466.3
GBP2
guanylate binding protein 2, interferon-inducible
chr8_-_57233103 0.50 ENST00000303749.3
ENST00000522671.1
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr14_+_62585332 0.49 ENST00000554895.1
LINC00643
long intergenic non-protein coding RNA 643
chr11_-_31531121 0.49 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr5_-_10761206 0.49 ENST00000432074.2
ENST00000230895.6
DAP
death-associated protein
chr5_+_8839844 0.49 ENST00000510229.1
ENST00000506655.1
ENST00000510067.1
RP11-143A12.3
RP11-143A12.3
chr1_+_41204506 0.48 ENST00000525290.1
ENST00000530965.1
ENST00000416859.2
ENST00000308733.5
NFYC
nuclear transcription factor Y, gamma
chr2_+_127413481 0.48 ENST00000259254.4
GYPC
glycophorin C (Gerbich blood group)
chr15_+_65822756 0.48 ENST00000562901.1
ENST00000261875.5
ENST00000442729.2
ENST00000565299.1
ENST00000568793.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr1_-_76076793 0.48 ENST00000370859.3
SLC44A5
solute carrier family 44, member 5
chr1_+_70820451 0.48 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HHLA3
HERV-H LTR-associating 3
chr1_-_93257951 0.47 ENST00000543509.1
ENST00000370331.1
ENST00000540033.1
EVI5
ecotropic viral integration site 5
chr1_+_22351977 0.47 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
LINC00339
long intergenic non-protein coding RNA 339
chr6_+_80129989 0.47 ENST00000429444.1
RP1-232L24.3
RP1-232L24.3
chr19_-_48752812 0.46 ENST00000359009.4
CARD8
caspase recruitment domain family, member 8
chr11_-_236326 0.45 ENST00000525237.1
ENST00000532956.1
ENST00000525319.1
ENST00000524564.1
ENST00000382743.4
SIRT3
sirtuin 3
chr3_-_93747425 0.45 ENST00000315099.2
STX19
syntaxin 19
chr8_+_104892639 0.45 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr6_-_119031228 0.44 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr2_+_54350316 0.44 ENST00000606865.1
ACYP2
acylphosphatase 2, muscle type
chr8_+_7353368 0.44 ENST00000355602.2
DEFB107B
defensin, beta 107B
chr3_+_108541545 0.43 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr15_+_65823092 0.43 ENST00000566074.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr3_+_69928256 0.43 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chrX_-_131228291 0.42 ENST00000370879.1
FRMD7
FERM domain containing 7
chr13_+_111855414 0.41 ENST00000375737.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr6_+_144904334 0.41 ENST00000367526.4
UTRN
utrophin
chr15_-_77376269 0.41 ENST00000558745.1
TSPAN3
tetraspanin 3
chr1_-_153283194 0.41 ENST00000290722.1
PGLYRP3
peptidoglycan recognition protein 3
chr3_+_20081515 0.40 ENST00000263754.4
KAT2B
K(lysine) acetyltransferase 2B
chr10_+_81462983 0.40 ENST00000448135.1
ENST00000429828.1
ENST00000372321.1
NUTM2B
NUT family member 2B
chr2_+_233527443 0.40 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr19_-_4540486 0.40 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chr17_+_4336955 0.40 ENST00000355530.2
SPNS3
spinster homolog 3 (Drosophila)
chr3_+_108541608 0.39 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr19_-_48753104 0.39 ENST00000447740.2
CARD8
caspase recruitment domain family, member 8
chr22_-_39268192 0.39 ENST00000216083.6
CBX6
chromobox homolog 6
chr5_-_157286104 0.38 ENST00000530742.1
ENST00000523908.1
ENST00000523094.1
ENST00000296951.5
ENST00000411809.2
CLINT1
clathrin interactor 1
chr1_+_196621002 0.38 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr10_-_13390270 0.38 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
SEPHS1
selenophosphate synthetase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of CDC5L

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.4 6.8 GO:0002399 MHC class II protein complex assembly(GO:0002399)
1.2 3.6 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.8 2.3 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.7 2.2 GO:0006711 estrogen catabolic process(GO:0006711)
0.7 2.0 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.7 2.0 GO:0070839 divalent metal ion export(GO:0070839)
0.6 2.9 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.5 1.4 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.4 1.1 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.4 1.4 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 2.7 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.3 1.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.3 2.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 0.7 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 1.3 GO:0060005 vestibular reflex(GO:0060005)
0.2 10.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 0.6 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.2 2.7 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.2 0.6 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.2 0.9 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.2 0.4 GO:0071284 cellular response to lead ion(GO:0071284)
0.2 1.4 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 1.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 0.5 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 1.7 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2 0.6 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.2 2.0 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.2 1.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 0.9 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.8 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.6 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 0.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.4 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.4 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 5.9 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.4 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 2.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.3 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.8 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 1.2 GO:0046415 urate metabolic process(GO:0046415)
0.1 1.3 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.1 1.5 GO:0019321 pentose metabolic process(GO:0019321)
0.1 1.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.8 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.3 GO:0042640 anagen(GO:0042640)
0.1 10.7 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 1.6 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.1 1.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.3 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.2 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.3 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.5 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.2 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.6 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.3 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 1.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 3.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 7.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 3.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.6 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.2 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 1.0 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.5 GO:0015871 choline transport(GO:0015871)
0.0 3.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.5 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.5 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.6 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.3 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.1 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.3 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.2 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 2.1 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 1.6 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.3 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.1 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.1 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.4 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.0 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.0 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.1 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.4 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:0045137 gonad development(GO:0008406) development of primary sexual characteristics(GO:0045137)
0.0 1.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.5 GO:0034198 cellular response to amino acid starvation(GO:0034198)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 17.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.5 5.1 GO:0036157 outer dynein arm(GO:0036157)
0.4 1.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3 2.4 GO:0036021 endolysosome lumen(GO:0036021)
0.2 1.5 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 0.6 GO:0030849 autosome(GO:0030849)
0.2 3.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 0.5 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 8.4 GO:0030286 dynein complex(GO:0030286)
0.1 1.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 0.8 GO:0001533 cornified envelope(GO:0001533)
0.1 0.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.4 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.8 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 3.2 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 2.1 GO:0005813 centrosome(GO:0005813)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 10.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.8 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.7 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 5.0 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.4 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.5 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.7 3.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.6 2.3 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.5 10.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.4 5.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.4 8.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.4 11.3 GO:0042605 peptide antigen binding(GO:0042605)
0.3 2.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.3 1.8 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.3 1.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.2 0.7 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.2 0.7 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 2.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 0.7 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 2.0 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.2 0.6 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 5.4 GO:0002162 dystroglycan binding(GO:0002162)
0.2 5.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 1.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 1.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 0.5 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2 0.8 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.6 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.4 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.6 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.4 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 1.5 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.4 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.6 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 2.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005) PH domain binding(GO:0042731)
0.1 2.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 3.6 GO:0043394 proteoglycan binding(GO:0043394)
0.1 0.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.2 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.2 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 2.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.1 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.0 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 1.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 1.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 1.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0070513 death domain binding(GO:0070513)
0.0 1.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 1.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 2.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 1.3 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.3 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 3.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.4 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 16.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.5 4.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.5 6.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.4 6.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 2.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 3.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 2.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 1.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 1.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.8 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.8 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.0 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.2 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC