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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for CEBPA

Z-value: 1.04

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Transcription factors associated with CEBPA

Gene Symbol Gene ID Gene Info
CEBPA
ENSG00000245848.2 CCAAT enhancer binding protein alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPAhg19_v2_chr19_-_33793430_337934700.523.1e-03Click!

Activity profile of CEBPA motif

Sorted Z-values of CEBPA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_32557610 5.23 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr12_+_69742121 3.53 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
LYZ
lysozyme
chr12_-_71551652 3.48 ENST00000546561.1
TSPAN8
tetraspanin 8
chr13_+_96085847 2.49 ENST00000376873.3
CLDN10
claudin 10
chr12_-_71551868 2.30 ENST00000247829.3
TSPAN8
tetraspanin 8
chr11_+_27062860 2.27 ENST00000528583.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_+_196621156 2.14 ENST00000359637.2
CFH
complement factor H
chr16_+_82090028 2.00 ENST00000568090.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr16_+_23765948 1.99 ENST00000300113.2
CHP2
calcineurin-like EF-hand protein 2
chr5_-_121413974 1.93 ENST00000231004.4
LOX
lysyl oxidase
chr3_+_13610216 1.88 ENST00000492059.1
FBLN2
fibulin 2
chr3_-_148939835 1.87 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr9_+_99690592 1.82 ENST00000354649.3
NUTM2G
NUT family member 2G
chr18_-_61311485 1.77 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr6_+_31895467 1.75 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr2_+_223289208 1.69 ENST00000321276.7
SGPP2
sphingosine-1-phosphate phosphatase 2
chr12_+_21207503 1.67 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr14_+_95078714 1.66 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr3_-_100712352 1.60 ENST00000471714.1
ENST00000284322.5
ABI3BP
ABI family, member 3 (NESH) binding protein
chr3_-_158450231 1.60 ENST00000479756.1
RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr5_-_160279207 1.55 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr1_+_196621002 1.54 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr18_-_61329118 1.40 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr11_+_27062502 1.38 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr19_-_6720686 1.37 ENST00000245907.6
C3
complement component 3
chr6_-_32920794 1.33 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA
XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr19_-_4540486 1.32 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chr11_+_27062272 1.30 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr11_+_27076764 1.27 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr12_+_20963647 1.26 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr1_-_207095324 1.26 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr12_+_20963632 1.24 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr5_+_156696362 1.23 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr6_+_126102292 1.23 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chr2_+_102721023 1.21 ENST00000409589.1
ENST00000409329.1
IL1R1
interleukin 1 receptor, type I
chr5_+_36608422 1.20 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_+_140947563 1.18 ENST00000505013.1
ACPL2
acid phosphatase-like 2
chr15_-_49255632 1.17 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr6_+_126240442 1.15 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr11_-_59633951 1.15 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr9_+_130911723 1.15 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr11_-_33913708 1.15 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr4_-_100356551 1.12 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr12_+_21168630 1.12 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr20_-_43883197 1.11 ENST00000338380.2
SLPI
secretory leukocyte peptidase inhibitor
chr19_+_41497178 1.08 ENST00000324071.4
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr11_+_123986069 1.08 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A
von Willebrand factor A domain containing 5A
chr4_+_74606223 1.07 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr2_+_228678550 1.06 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chrX_-_15620192 1.06 ENST00000427411.1
ACE2
angiotensin I converting enzyme 2
chr17_+_1665345 1.04 ENST00000576406.1
ENST00000571149.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr1_+_117544366 0.97 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr1_+_110082487 0.97 ENST00000527748.1
GPR61
G protein-coupled receptor 61
chr9_+_130911770 0.96 ENST00000372998.1
LCN2
lipocalin 2
chr22_+_35776828 0.94 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chrX_+_125953746 0.94 ENST00000371125.3
CXorf64
chromosome X open reading frame 64
chr4_-_100356844 0.92 ENST00000437033.2
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr5_-_159739532 0.92 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL
cyclin J-like
chr11_-_5271122 0.91 ENST00000330597.3
HBG1
hemoglobin, gamma A
chr16_-_55866997 0.87 ENST00000360526.3
ENST00000361503.4
CES1
carboxylesterase 1
chr19_-_54876558 0.85 ENST00000391742.2
ENST00000434277.2
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr11_-_18270182 0.84 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr12_+_7167980 0.82 ENST00000360817.5
ENST00000402681.3
C1S
complement component 1, s subcomponent
chr5_+_125758813 0.79 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr5_+_125758865 0.79 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr3_-_66551397 0.78 ENST00000383703.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr17_-_67264947 0.78 ENST00000586811.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr17_+_72427477 0.78 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr5_+_140602904 0.78 ENST00000515856.2
ENST00000239449.4
PCDHB14
protocadherin beta 14
chr11_+_18287721 0.77 ENST00000356524.4
SAA1
serum amyloid A1
chr4_-_70725856 0.76 ENST00000226444.3
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr5_+_140557371 0.76 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr11_+_18287801 0.75 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr1_-_114429997 0.75 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr19_-_54676884 0.73 ENST00000376591.4
TMC4
transmembrane channel-like 4
chr17_+_1665253 0.72 ENST00000254722.4
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr14_-_23285011 0.72 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_-_21516590 0.71 ENST00000555026.1
NDRG2
NDRG family member 2
chr6_-_33037019 0.70 ENST00000437811.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr19_-_54676846 0.69 ENST00000301187.4
TMC4
transmembrane channel-like 4
chr10_+_114133773 0.69 ENST00000354655.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr17_+_20059302 0.68 ENST00000395530.2
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr5_+_140227048 0.67 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr17_+_72426891 0.67 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr3_-_66551351 0.67 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr10_-_116444371 0.66 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr1_+_110162448 0.65 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
AMPD2
adenosine monophosphate deaminase 2
chr19_+_49258775 0.65 ENST00000593756.1
FGF21
fibroblast growth factor 21
chr16_+_57481382 0.64 ENST00000564655.1
ENST00000567072.1
ENST00000567933.1
ENST00000563166.1
COQ9
coenzyme Q9
chr7_-_138386097 0.63 ENST00000421622.1
SVOPL
SVOP-like
chr7_+_26191809 0.63 ENST00000056233.3
NFE2L3
nuclear factor, erythroid 2-like 3
chr10_+_95848824 0.63 ENST00000371385.3
ENST00000371375.1
PLCE1
phospholipase C, epsilon 1
chr19_+_50084561 0.62 ENST00000246794.5
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr4_+_86699834 0.62 ENST00000395183.2
ARHGAP24
Rho GTPase activating protein 24
chr2_-_99279928 0.61 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr4_+_48485341 0.61 ENST00000273861.4
SLC10A4
solute carrier family 10, member 4
chr5_-_137475071 0.59 ENST00000265191.2
NME5
NME/NM23 family member 5
chr10_+_91589261 0.59 ENST00000448963.1
LINC00865
long intergenic non-protein coding RNA 865
chr7_-_121944491 0.58 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr14_-_23285069 0.57 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr12_-_13248598 0.57 ENST00000337630.6
ENST00000545699.1
GSG1
germ cell associated 1
chr6_-_133055815 0.57 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr18_-_5396271 0.56 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr9_+_2029019 0.55 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_-_681114 0.55 ENST00000503156.1
MFSD7
major facilitator superfamily domain containing 7
chr6_+_31895480 0.53 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr9_-_99382065 0.52 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
CDC14B
cell division cycle 14B
chr19_-_54876414 0.52 ENST00000474878.1
ENST00000348231.4
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr15_-_55657428 0.51 ENST00000568543.1
CCPG1
cell cycle progression 1
chr14_-_90798273 0.50 ENST00000357904.3
NRDE2
NRDE-2, necessary for RNA interference, domain containing
chr2_+_143635067 0.49 ENST00000264170.4
KYNU
kynureninase
chr6_+_130339710 0.49 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr2_+_143635222 0.48 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
KYNU
kynureninase
chr12_+_29376592 0.48 ENST00000182377.4
FAR2
fatty acyl CoA reductase 2
chr8_+_27348649 0.47 ENST00000521780.1
ENST00000380476.3
ENST00000518379.1
ENST00000521684.1
EPHX2
epoxide hydrolase 2, cytoplasmic
chrX_+_139791917 0.47 ENST00000607004.1
ENST00000370535.3
LINC00632
long intergenic non-protein coding RNA 632
chr12_-_91572278 0.46 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
DCN
decorin
chr7_-_112635675 0.46 ENST00000447785.1
ENST00000451962.1
AC018464.3
AC018464.3
chr7_+_101460882 0.45 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1
cut-like homeobox 1
chr10_+_5005598 0.45 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr19_-_37019562 0.45 ENST00000523638.1
ZNF260
zinc finger protein 260
chr5_-_124081008 0.45 ENST00000306315.5
ZNF608
zinc finger protein 608
chr6_+_27833034 0.45 ENST00000357320.2
HIST1H2AL
histone cluster 1, H2al
chr4_-_119274121 0.45 ENST00000296498.3
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr1_-_114430169 0.44 ENST00000393316.3
BCL2L15
BCL2-like 15
chr12_-_86230315 0.44 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr14_+_77582905 0.43 ENST00000557408.1
TMEM63C
transmembrane protein 63C
chrX_+_153409678 0.43 ENST00000369951.4
OPN1LW
opsin 1 (cone pigments), long-wave-sensitive
chr6_+_29910301 0.43 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr11_-_102668879 0.42 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chrX_+_153448107 0.42 ENST00000369935.5
OPN1MW
opsin 1 (cone pigments), medium-wave-sensitive
chr6_+_117002339 0.42 ENST00000413340.1
ENST00000368564.1
ENST00000356348.1
KPNA5
karyopherin alpha 5 (importin alpha 6)
chr1_+_12524965 0.41 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr2_-_225362533 0.41 ENST00000451538.1
CUL3
cullin 3
chr15_-_63450192 0.41 ENST00000411926.1
RPS27L
ribosomal protein S27-like
chr12_+_29376673 0.41 ENST00000547116.1
FAR2
fatty acyl CoA reductase 2
chr3_-_112218378 0.40 ENST00000334529.5
BTLA
B and T lymphocyte associated
chr1_+_169079823 0.40 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr15_+_71228826 0.39 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr6_+_31895254 0.39 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr19_+_4304585 0.39 ENST00000221856.6
FSD1
fibronectin type III and SPRY domain containing 1
chr1_+_245133062 0.39 ENST00000366523.1
EFCAB2
EF-hand calcium binding domain 2
chr10_-_61469837 0.39 ENST00000395348.3
SLC16A9
solute carrier family 16, member 9
chr6_+_27782788 0.38 ENST00000359465.4
HIST1H2BM
histone cluster 1, H2bm
chr10_+_5005445 0.38 ENST00000380872.4
AKR1C1
aldo-keto reductase family 1, member C1
chr12_-_123187890 0.38 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr15_-_74501310 0.38 ENST00000423167.2
ENST00000432245.2
STRA6
stimulated by retinoic acid 6
chr2_-_152382500 0.38 ENST00000434685.1
NEB
nebulin
chr10_+_118187379 0.37 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr9_-_125027079 0.37 ENST00000417201.3
RBM18
RNA binding motif protein 18
chr5_+_49963239 0.37 ENST00000505554.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr11_-_111944704 0.37 ENST00000532211.1
PIH1D2
PIH1 domain containing 2
chr12_-_123201337 0.37 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr21_-_46348694 0.37 ENST00000355153.4
ENST00000397850.2
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr14_+_21387508 0.36 ENST00000555624.1
RP11-84C10.2
RP11-84C10.2
chr13_-_20805109 0.36 ENST00000241124.6
GJB6
gap junction protein, beta 6, 30kDa
chr10_-_70092671 0.36 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
PBLD
phenazine biosynthesis-like protein domain containing
chr2_-_32490859 0.35 ENST00000404025.2
NLRC4
NLR family, CARD domain containing 4
chr17_+_57287228 0.35 ENST00000578922.1
ENST00000300917.5
SMG8
SMG8 nonsense mediated mRNA decay factor
chr1_+_41827594 0.35 ENST00000372591.1
FOXO6
forkhead box O6
chr17_-_2415169 0.35 ENST00000263092.6
ENST00000538844.1
ENST00000576976.1
METTL16
methyltransferase like 16
chr6_-_30043539 0.35 ENST00000376751.3
ENST00000244360.6
RNF39
ring finger protein 39
chr2_+_234590556 0.35 ENST00000373426.3
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr10_-_45474237 0.35 ENST00000448778.1
ENST00000298295.3
C10orf10
chromosome 10 open reading frame 10
chr6_-_133055896 0.35 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr1_-_157014865 0.35 ENST00000361409.2
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr15_-_55790515 0.34 ENST00000448430.2
ENST00000457155.2
DYX1C1
dyslexia susceptibility 1 candidate 1
chr18_-_30716038 0.34 ENST00000581852.1
CCDC178
coiled-coil domain containing 178
chr16_+_72088376 0.34 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr2_-_198650037 0.34 ENST00000392296.4
BOLL
boule-like RNA-binding protein
chrX_+_49644470 0.34 ENST00000508866.2
USP27X
ubiquitin specific peptidase 27, X-linked
chr3_-_47517302 0.33 ENST00000441517.2
ENST00000545718.1
SCAP
SREBF chaperone
chr4_-_48136217 0.33 ENST00000264316.4
TXK
TXK tyrosine kinase
chr2_+_163200598 0.33 ENST00000437150.2
ENST00000453113.2
GCA
grancalcin, EF-hand calcium binding protein
chr11_-_26593677 0.33 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr11_+_7597639 0.32 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr6_+_30457244 0.32 ENST00000376630.4
HLA-E
major histocompatibility complex, class I, E
chr1_+_248201474 0.32 ENST00000366479.2
OR2L2
olfactory receptor, family 2, subfamily L, member 2
chr10_-_61900762 0.32 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr17_+_21030260 0.32 ENST00000579303.1
DHRS7B
dehydrogenase/reductase (SDR family) member 7B
chr9_-_28670283 0.32 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chrX_+_54834159 0.31 ENST00000375053.2
ENST00000347546.4
ENST00000375062.4
MAGED2
melanoma antigen family D, 2
chr1_-_186649543 0.31 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr12_-_62586543 0.31 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr19_-_46272462 0.31 ENST00000317578.6
SIX5
SIX homeobox 5
chr13_+_111267866 0.31 ENST00000458711.2
ENST00000424185.2
ENST00000397191.4
ENST00000309957.2
CARKD
carbohydrate kinase domain containing
chr22_+_31518938 0.31 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr11_+_86667117 0.30 ENST00000531827.1
RP11-736K20.6
RP11-736K20.6
chr1_-_159684371 0.30 ENST00000255030.5
ENST00000437342.1
ENST00000368112.1
ENST00000368111.1
ENST00000368110.1
ENST00000343919.2
CRP
C-reactive protein, pentraxin-related
chr2_+_234545148 0.30 ENST00000373445.1
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr18_-_53070913 0.30 ENST00000568186.1
ENST00000564228.1
TCF4
transcription factor 4
chr10_-_127505167 0.30 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr5_-_150473127 0.30 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr19_-_40596767 0.30 ENST00000599972.1
ENST00000450241.2
ENST00000595687.2
ZNF780A
zinc finger protein 780A
chr19_+_1450112 0.30 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
APC2
adenomatosis polyposis coli 2
chr1_+_248402231 0.29 ENST00000306687.1
OR2M4
olfactory receptor, family 2, subfamily M, member 4
chr19_+_56652556 0.29 ENST00000337080.3
ZNF444
zinc finger protein 444
chrX_-_10588595 0.29 ENST00000423614.1
ENST00000317552.4
MID1
midline 1 (Opitz/BBB syndrome)
chr11_+_67806467 0.29 ENST00000265686.3
ENST00000524598.1
ENST00000529657.1
TCIRG1
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
chrX_+_54834004 0.28 ENST00000375068.1
MAGED2
melanoma antigen family D, 2

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.6 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.7 2.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.7 2.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.6 6.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.5 1.4 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.4 2.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.4 1.2 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.4 1.1 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.4 1.8 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.4 1.4 GO:0035425 autocrine signaling(GO:0035425)
0.3 1.0 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.3 0.9 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.3 1.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.3 0.8 GO:0006711 estrogen catabolic process(GO:0006711)
0.2 3.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 0.9 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.2 1.3 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.2 1.1 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.2 4.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 2.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.9 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 1.3 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.7 GO:1904640 response to methionine(GO:1904640)
0.1 1.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 6.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.6 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 1.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 2.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.5 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.5 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.5 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.1 1.2 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.3 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 0.2 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.3 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.8 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 1.5 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 1.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.9 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.3 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.3 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 0.3 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 1.0 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 0.3 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.3 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 2.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.7 GO:0032264 IMP salvage(GO:0032264)
0.1 0.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 1.9 GO:0006825 copper ion transport(GO:0006825)
0.1 0.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.1 GO:0008217 regulation of blood pressure(GO:0008217)
0.1 1.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.1 1.6 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.2 GO:0048863 stem cell differentiation(GO:0048863)
0.1 0.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.2 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 0.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.2 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 0.3 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 0.2 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.4 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.7 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.3 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0071105 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340) response to interleukin-11(GO:0071105)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 1.1 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.9 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.7 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.2 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.9 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.2 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 1.3 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.4 GO:0070269 pyroptosis(GO:0070269)
0.0 0.6 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.7 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.2 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 2.4 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 1.1 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0046434 purine nucleotide catabolic process(GO:0006195) nucleotide catabolic process(GO:0009166) organophosphate catabolic process(GO:0046434) nucleoside phosphate catabolic process(GO:1901292)
0.0 0.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.5 GO:0071402 cellular response to lipoprotein particle stimulus(GO:0071402) cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 3.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.3 GO:0051168 nuclear export(GO:0051168)
0.0 0.4 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.7 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.5 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.4 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.9 GO:0050918 positive chemotaxis(GO:0050918)
0.0 0.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.4 GO:0019054 modulation by virus of host process(GO:0019054)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0061025 membrane fusion(GO:0061025)
0.0 0.2 GO:0018393 histone acetylation(GO:0016573) internal peptidyl-lysine acetylation(GO:0018393)
0.0 0.2 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.2 GO:0046606 negative regulation of centrosome cycle(GO:0046606)
0.0 0.3 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.1 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 2.0 GO:0043203 axon hillock(GO:0043203)
0.1 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.5 GO:1990037 Lewy body core(GO:1990037)
0.1 1.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 6.3 GO:0035580 specific granule lumen(GO:0035580)
0.1 0.9 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.5 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 1.2 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.4 GO:0005827 polar microtubule(GO:0005827)
0.0 4.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.8 GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.9 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.9 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 5.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 1.2 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 1.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.7 2.8 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.5 2.0 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.4 1.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.4 1.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.3 0.9 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.3 1.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.3 6.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 7.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 3.4 GO:0003796 lysozyme activity(GO:0003796)
0.2 1.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.9 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 0.9 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 0.9 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 1.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 1.0 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 1.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 3.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.8 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.8 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 1.2 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.3 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.3 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.4 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.7 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 3.1 GO:0001848 complement binding(GO:0001848)
0.1 0.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.2 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.3 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 0.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.3 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 1.0 GO:0008494 translation activator activity(GO:0008494)
0.1 0.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 2.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 1.0 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 5.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 2.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 5.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 2.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 1.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 1.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 2.0 GO:0002020 protease binding(GO:0002020)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 3.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 4.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 6.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 4.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 5.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 2.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.9 REACTOME OPSINS Genes involved in Opsins
0.1 0.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 2.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 3.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK