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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for CEBPE_CEBPD

Z-value: 1.17

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Transcription factors associated with CEBPE_CEBPD

Gene Symbol Gene ID Gene Info
CEBPE
ENSG00000092067.5 CCAAT enhancer binding protein epsilon
CEBPD
ENSG00000221869.4 CCAAT enhancer binding protein delta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPDhg19_v2_chr8_-_48651648_486516480.791.6e-07Click!
CEBPEhg19_v2_chr14_-_23588816_235888360.251.7e-01Click!

Activity profile of CEBPE_CEBPD motif

Sorted Z-values of CEBPE_CEBPD motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_216300784 7.78 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr2_-_113594279 6.48 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr1_-_186649543 6.44 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr8_-_6735451 6.03 ENST00000297439.3
DEFB1
defensin, beta 1
chr2_-_31637560 4.84 ENST00000379416.3
XDH
xanthine dehydrogenase
chr8_+_124194875 4.07 ENST00000522648.1
ENST00000276699.6
FAM83A
family with sequence similarity 83, member A
chr8_+_124194752 3.99 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr20_+_33759854 3.56 ENST00000216968.4
PROCR
protein C receptor, endothelial
chr9_-_94186131 3.50 ENST00000297689.3
NFIL3
nuclear factor, interleukin 3 regulated
chr2_+_113885138 3.14 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr20_-_52790512 2.90 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr1_+_154377669 2.84 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr14_+_20937538 2.68 ENST00000361505.5
ENST00000553591.1
PNP
purine nucleoside phosphorylase
chr11_-_18270182 2.60 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr11_+_18287801 2.43 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr11_+_18287721 2.42 ENST00000356524.4
SAA1
serum amyloid A1
chr16_-_84651647 2.38 ENST00000564057.1
COTL1
coactosin-like 1 (Dictyostelium)
chr4_-_139163491 2.32 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr12_-_123201337 2.31 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr12_-_123187890 2.31 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr16_-_84651673 2.28 ENST00000262428.4
COTL1
coactosin-like 1 (Dictyostelium)
chr10_+_17270214 2.22 ENST00000544301.1
VIM
vimentin
chr6_-_112194484 1.86 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN
FYN oncogene related to SRC, FGR, YES
chr19_-_36019123 1.85 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN
suprabasin
chr10_-_17659234 1.73 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr5_+_49963239 1.71 ENST00000505554.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr10_-_75226166 1.70 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr7_-_83824169 1.69 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr7_-_121944491 1.66 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr6_-_133055896 1.60 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr19_-_40971643 1.55 ENST00000595483.1
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr19_-_40971667 1.54 ENST00000263368.4
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr19_+_39903185 1.52 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chrX_+_138612889 1.47 ENST00000218099.2
ENST00000394090.2
F9
coagulation factor IX
chr12_+_29376592 1.43 ENST00000182377.4
FAR2
fatty acyl CoA reductase 2
chr12_+_29376673 1.42 ENST00000547116.1
FAR2
fatty acyl CoA reductase 2
chr6_-_133055815 1.26 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr2_-_101925055 1.23 ENST00000295317.3
RNF149
ring finger protein 149
chr3_-_16306432 1.17 ENST00000383775.4
ENST00000488423.1
DPH3
diphthamide biosynthesis 3
chr17_+_2699697 1.14 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2
RAP1 GTPase activating protein 2
chr10_-_17659357 1.09 ENST00000326961.6
ENST00000361271.3
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr5_-_140013275 1.09 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr4_-_122744998 1.05 ENST00000274026.5
CCNA2
cyclin A2
chr6_-_30043539 1.05 ENST00000376751.3
ENST00000244360.6
RNF39
ring finger protein 39
chr15_+_45926919 1.05 ENST00000561735.1
ENST00000260324.7
SQRDL
sulfide quinone reductase-like (yeast)
chr8_-_124553437 1.04 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr3_+_12392971 1.00 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr16_-_67597789 0.99 ENST00000605277.1
CTD-2012K14.6
CTD-2012K14.6
chr20_-_22566089 0.97 ENST00000377115.4
FOXA2
forkhead box A2
chr2_-_68694390 0.92 ENST00000377957.3
FBXO48
F-box protein 48
chr5_-_147286065 0.92 ENST00000318315.4
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr3_-_99595037 0.86 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr2_-_61245363 0.85 ENST00000316752.6
PUS10
pseudouridylate synthase 10
chr15_+_40886199 0.84 ENST00000346991.5
ENST00000528975.1
ENST00000527044.1
CASC5
cancer susceptibility candidate 5
chr2_+_68694678 0.81 ENST00000303795.4
APLF
aprataxin and PNKP like factor
chr15_+_39873268 0.79 ENST00000397591.2
ENST00000260356.5
THBS1
thrombospondin 1
chrX_-_40506766 0.77 ENST00000378421.1
ENST00000440784.2
ENST00000327877.5
ENST00000378426.1
ENST00000378418.2
CXorf38
chromosome X open reading frame 38
chr18_-_29340827 0.73 ENST00000269205.5
SLC25A52
solute carrier family 25, member 52
chr3_+_16306691 0.73 ENST00000285083.5
ENST00000605932.1
ENST00000435829.2
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr14_+_102276192 0.72 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr3_+_130569429 0.72 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr18_+_32621324 0.72 ENST00000300249.5
ENST00000538170.2
ENST00000588910.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr3_+_16306837 0.68 ENST00000606098.1
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr11_+_62495997 0.67 ENST00000316461.4
TTC9C
tetratricopeptide repeat domain 9C
chr1_+_165797024 0.67 ENST00000372212.4
UCK2
uridine-cytidine kinase 2
chr1_-_114430169 0.66 ENST00000393316.3
BCL2L15
BCL2-like 15
chr11_-_105948040 0.64 ENST00000534815.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr13_-_21634421 0.63 ENST00000542899.1
LATS2
large tumor suppressor kinase 2
chr14_-_45722605 0.63 ENST00000310806.4
MIS18BP1
MIS18 binding protein 1
chr7_+_22766766 0.63 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr17_+_57287228 0.61 ENST00000578922.1
ENST00000300917.5
SMG8
SMG8 nonsense mediated mRNA decay factor
chr11_-_105948129 0.61 ENST00000526793.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr17_+_7461849 0.59 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr3_+_133465228 0.59 ENST00000482271.1
ENST00000264998.3
TF
transferrin
chr6_+_31895467 0.59 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr15_+_58430567 0.58 ENST00000536493.1
AQP9
aquaporin 9
chr3_-_58200398 0.57 ENST00000318316.3
ENST00000460422.1
ENST00000483681.1
DNASE1L3
deoxyribonuclease I-like 3
chr4_+_55095264 0.56 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr17_+_7461781 0.55 ENST00000349228.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr19_-_41945804 0.55 ENST00000221943.9
ENST00000597457.1
ENST00000589970.1
ENST00000595425.1
ENST00000438807.3
ENST00000589102.1
ENST00000592922.2
ATP5SL
ATP5S-like
chr1_+_196857144 0.54 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4
complement factor H-related 4
chr11_-_18258342 0.54 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr19_+_1383890 0.53 ENST00000539480.1
ENST00000313408.7
ENST00000414651.2
NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr6_+_4776580 0.52 ENST00000397588.3
CDYL
chromodomain protein, Y-like
chr3_-_99594948 0.51 ENST00000471562.1
ENST00000495625.2
FILIP1L
filamin A interacting protein 1-like
chr20_+_54987168 0.50 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chr15_+_58430368 0.50 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr13_-_24007815 0.50 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr5_-_132113036 0.49 ENST00000378706.1
SEPT8
septin 8
chr4_-_76928641 0.49 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr9_+_110045537 0.48 ENST00000358015.3
RAD23B
RAD23 homolog B (S. cerevisiae)
chr1_-_38100491 0.48 ENST00000356545.2
RSPO1
R-spondin 1
chr16_+_70680439 0.47 ENST00000288098.2
IL34
interleukin 34
chr20_-_33732952 0.47 ENST00000541621.1
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr8_-_134309335 0.46 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1
N-myc downstream regulated 1
chr20_+_54987305 0.46 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr3_-_158450231 0.45 ENST00000479756.1
RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr3_+_101504200 0.45 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr1_+_196743912 0.45 ENST00000367425.4
CFHR3
complement factor H-related 3
chr3_+_11314099 0.45 ENST00000446450.2
ENST00000354956.5
ENST00000354449.3
ENST00000419112.1
ATG7
autophagy related 7
chr3_-_158450475 0.43 ENST00000237696.5
RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr8_-_134309823 0.43 ENST00000414097.2
NDRG1
N-myc downstream regulated 1
chr19_-_2042065 0.43 ENST00000591588.1
ENST00000591142.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr11_-_18062872 0.43 ENST00000250018.2
TPH1
tryptophan hydroxylase 1
chr1_-_67519782 0.42 ENST00000235345.5
SLC35D1
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr2_-_191878162 0.41 ENST00000540176.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr1_+_111770278 0.41 ENST00000369748.4
CHI3L2
chitinase 3-like 2
chr4_-_114682224 0.41 ENST00000342666.5
ENST00000515496.1
ENST00000514328.1
ENST00000508738.1
ENST00000379773.2
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr6_+_101846664 0.41 ENST00000421544.1
ENST00000413795.1
ENST00000369138.1
ENST00000358361.3
GRIK2
glutamate receptor, ionotropic, kainate 2
chr14_-_72458326 0.40 ENST00000542853.1
AC005477.1
AC005477.1
chr4_-_114682364 0.39 ENST00000511664.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr6_-_99797522 0.39 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr1_+_111770232 0.39 ENST00000369744.2
CHI3L2
chitinase 3-like 2
chr3_+_186435137 0.39 ENST00000447445.1
KNG1
kininogen 1
chr11_+_62495541 0.39 ENST00000530625.1
ENST00000513247.2
TTC9C
tetratricopeptide repeat domain 9C
chr17_+_7462103 0.39 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr12_+_110011571 0.39 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr3_+_121902511 0.38 ENST00000490131.1
CASR
calcium-sensing receptor
chr17_+_7462031 0.37 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr5_+_95998070 0.37 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
CAST
calpastatin
chr12_+_13197218 0.37 ENST00000197268.8
KIAA1467
KIAA1467
chr12_-_53074182 0.37 ENST00000252244.3
KRT1
keratin 1
chr1_+_82266053 0.36 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr1_+_196743943 0.36 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr4_-_114682597 0.36 ENST00000394524.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr4_-_114682936 0.36 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr16_-_21663919 0.35 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr1_-_161087802 0.35 ENST00000368010.3
PFDN2
prefoldin subunit 2
chr7_+_90032667 0.35 ENST00000496677.1
ENST00000287916.4
ENST00000535571.1
ENST00000394604.1
ENST00000394605.2
CLDN12
claudin 12
chr15_+_67418047 0.34 ENST00000540846.2
SMAD3
SMAD family member 3
chr19_+_56989609 0.34 ENST00000601875.1
ZNF667-AS1
ZNF667 antisense RNA 1 (head to head)
chr16_+_72088376 0.33 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr5_-_132113559 0.33 ENST00000448933.1
SEPT8
septin 8
chr1_-_62784935 0.33 ENST00000354381.3
KANK4
KN motif and ankyrin repeat domains 4
chr17_-_79895097 0.32 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
PYCR1
pyrroline-5-carboxylate reductase 1
chr14_-_106573756 0.31 ENST00000390601.2
IGHV3-11
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr9_-_77502636 0.30 ENST00000449912.2
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr6_+_1389989 0.30 ENST00000259806.1
FOXF2
forkhead box F2
chr1_+_192127578 0.30 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr20_+_4666882 0.30 ENST00000379440.4
ENST00000430350.2
PRNP
prion protein
chr15_+_40886439 0.30 ENST00000532056.1
ENST00000399668.2
CASC5
cancer susceptibility candidate 5
chr10_-_92681033 0.30 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr17_-_79895154 0.29 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
PYCR1
pyrroline-5-carboxylate reductase 1
chr1_-_47697387 0.29 ENST00000371884.2
TAL1
T-cell acute lymphocytic leukemia 1
chr19_-_35992780 0.29 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr4_+_96012614 0.29 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB
chrX_-_105282712 0.29 ENST00000372563.1
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr21_+_33671160 0.28 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr4_+_78079450 0.28 ENST00000395640.1
ENST00000512918.1
CCNG2
cyclin G2
chr1_-_204183071 0.28 ENST00000308302.3
GOLT1A
golgi transport 1A
chr3_+_141043050 0.28 ENST00000509842.1
ZBTB38
zinc finger and BTB domain containing 38
chr8_-_25315905 0.28 ENST00000221200.4
KCTD9
potassium channel tetramerization domain containing 9
chr12_+_66582919 0.28 ENST00000545837.1
ENST00000457197.2
IRAK3
interleukin-1 receptor-associated kinase 3
chr2_-_191885686 0.28 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr2_-_191878874 0.27 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
STAT1
signal transducer and activator of transcription 1, 91kDa
chr4_+_78079570 0.27 ENST00000509972.1
CCNG2
cyclin G2
chr19_+_48949030 0.26 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr7_-_36764004 0.26 ENST00000431169.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr16_-_21663950 0.26 ENST00000268389.4
IGSF6
immunoglobulin superfamily, member 6
chr3_+_136649311 0.26 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr3_-_122233723 0.26 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr20_+_62716348 0.25 ENST00000349451.3
OPRL1
opiate receptor-like 1
chr14_+_61201445 0.25 ENST00000261245.4
ENST00000539616.2
MNAT1
MNAT CDK-activating kinase assembly factor 1
chr2_-_191878681 0.24 ENST00000409465.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr3_-_4793274 0.24 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr22_+_48972118 0.24 ENST00000358295.5
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr6_+_31895480 0.24 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr12_-_91573316 0.24 ENST00000393155.1
DCN
decorin
chr19_+_45174724 0.24 ENST00000358777.4
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr17_-_7017968 0.24 ENST00000355035.5
ASGR2
asialoglycoprotein receptor 2
chr17_-_41277317 0.23 ENST00000497488.1
ENST00000489037.1
ENST00000470026.1
ENST00000586385.1
ENST00000591534.1
ENST00000591849.1
BRCA1
breast cancer 1, early onset
chr12_+_7167980 0.23 ENST00000360817.5
ENST00000402681.3
C1S
complement component 1, s subcomponent
chr5_-_132113083 0.23 ENST00000296873.7
SEPT8
septin 8
chr14_+_64971292 0.23 ENST00000358738.3
ENST00000394712.2
ZBTB1
zinc finger and BTB domain containing 1
chr2_+_11674213 0.23 ENST00000381486.2
GREB1
growth regulation by estrogen in breast cancer 1
chr17_-_77813186 0.23 ENST00000448310.1
ENST00000269397.4
CBX4
chromobox homolog 4
chr10_+_90750378 0.23 ENST00000355740.2
ENST00000352159.4
FAS
Fas cell surface death receptor
chr5_-_39364586 0.23 ENST00000263408.4
C9
complement component 9
chr7_+_23145884 0.22 ENST00000409689.1
ENST00000410047.1
KLHL7
kelch-like family member 7
chrX_+_24483338 0.21 ENST00000379162.4
ENST00000441463.2
PDK3
pyruvate dehydrogenase kinase, isozyme 3
chr17_+_73089382 0.21 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr5_+_95997769 0.20 ENST00000338252.3
ENST00000508830.1
CAST
calpastatin
chr17_-_7018128 0.20 ENST00000380952.2
ENST00000254850.7
ASGR2
asialoglycoprotein receptor 2
chr6_+_167704838 0.20 ENST00000366829.2
UNC93A
unc-93 homolog A (C. elegans)
chr1_+_161087873 0.20 ENST00000368009.2
ENST00000368007.4
ENST00000368008.1
ENST00000392190.5
NIT1
nitrilase 1
chr7_-_141957847 0.20 ENST00000552471.1
ENST00000547058.2
PRSS58
protease, serine, 58
chr6_+_108977520 0.20 ENST00000540898.1
FOXO3
forkhead box O3
chr11_-_33795893 0.20 ENST00000526785.1
ENST00000534136.1
ENST00000265651.3
ENST00000530401.1
ENST00000448981.2
FBXO3
F-box protein 3
chr2_+_87755054 0.20 ENST00000423846.1
LINC00152
long intergenic non-protein coding RNA 152
chr10_+_14880287 0.20 ENST00000437161.2
HSPA14
heat shock 70kDa protein 14
chr15_+_81293254 0.20 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr17_+_27181956 0.19 ENST00000254928.5
ENST00000580917.2
ERAL1
Era-like 12S mitochondrial rRNA chaperone 1
chr2_-_99279928 0.19 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr10_+_90750493 0.19 ENST00000357339.2
ENST00000355279.2
FAS
Fas cell surface death receptor
chr16_-_53537105 0.19 ENST00000568596.1
ENST00000570004.1
ENST00000564497.1
ENST00000300245.4
ENST00000394657.7
AKTIP
AKT interacting protein
chr10_-_128994422 0.19 ENST00000522781.1
FAM196A
family with sequence similarity 196, member A
chr2_-_209118974 0.19 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr2_+_87754989 0.18 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152
long intergenic non-protein coding RNA 152
chr12_-_91573249 0.18 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr20_-_39946237 0.18 ENST00000441102.2
ENST00000559234.1
ZHX3
zinc fingers and homeoboxes 3

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPE_CEBPD

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
2.2 6.5 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
2.1 6.4 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
1.5 6.0 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
1.3 2.7 GO:0046102 inosine metabolic process(GO:0046102)
1.2 4.8 GO:0046110 xanthine metabolic process(GO:0046110)
1.2 3.5 GO:0002384 hepatic immune response(GO:0002384)
1.0 2.9 GO:0042369 vitamin D catabolic process(GO:0042369)
0.5 2.8 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.4 3.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.4 2.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.4 1.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.3 1.7 GO:0048880 sensory system development(GO:0048880)
0.3 1.0 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.3 1.2 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.3 0.6 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.3 1.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 1.1 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.3 2.9 GO:0015939 pantothenate metabolic process(GO:0015939)
0.3 0.8 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.2 1.0 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.2 1.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 3.1 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.2 2.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.2 2.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.2 1.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 1.7 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.2 0.7 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 1.9 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.2 0.5 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1 0.4 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 8.4 GO:0006953 acute-phase response(GO:0006953)
0.1 0.6 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.3 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.1 0.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.2 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 1.5 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.4 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 1.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.8 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.1 0.4 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.3 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.1 1.0 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.3 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.1 0.6 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 0.9 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.1 0.3 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 0.8 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.2 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 3.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.4 GO:0097527 Fas signaling pathway(GO:0036337) necroptotic signaling pathway(GO:0097527)
0.1 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.8 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 2.3 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 2.6 GO:0050832 defense response to fungus(GO:0050832)
0.1 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.3 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 3.3 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 8.0 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.6 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.1 GO:0050717 regulation of interleukin-1 alpha secretion(GO:0050705) positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.5 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218) cell migration involved in vasculogenesis(GO:0035441)
0.0 0.7 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.0 0.5 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.7 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.6 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.7 GO:0043067 regulation of apoptotic process(GO:0042981) regulation of programmed cell death(GO:0043067)
0.0 0.3 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 1.1 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0051495 positive regulation of cytoskeleton organization(GO:0051495)
0.0 0.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:1990742 microvesicle(GO:1990742)
0.9 3.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.7 8.6 GO:0005577 fibrinogen complex(GO:0005577)
0.4 1.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.2 1.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 6.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 2.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 6.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.5 GO:0070852 cell body fiber(GO:0070852)
0.0 0.6 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 5.0 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 6.1 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.5 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 2.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.7 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.1 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 3.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 1.5 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
1.6 6.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.0 3.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.9 2.8 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.9 2.7 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.8 3.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.6 2.9 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.6 2.9 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.6 2.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.5 4.8 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.5 8.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.5 2.3 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.3 2.2 GO:1990254 keratin filament binding(GO:1990254)
0.3 1.9 GO:0042610 CD8 receptor binding(GO:0042610)
0.3 6.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.3 1.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.3 0.8 GO:0070052 collagen V binding(GO:0070052)
0.2 1.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 0.6 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 1.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 0.6 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 7.5 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 1.0 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.6 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 5.9 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.5 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.3 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.4 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 3.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1 0.8 GO:0004568 chitinase activity(GO:0004568)
0.1 0.7 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.8 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 3.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.5 GO:0048038 quinone binding(GO:0048038)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 1.1 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0032183 SUMO binding(GO:0032183)
0.0 0.6 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 7.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 6.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.2 5.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 0.6 ST STAT3 PATHWAY STAT3 Pathway
0.1 2.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.4 PID AURORA B PATHWAY Aurora B signaling
0.0 1.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.2 PID FOXO PATHWAY FoxO family signaling
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 4.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 7.8 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2 3.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 5.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 4.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 7.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 3.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 3.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 7.3 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 3.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.4 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements