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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for CLOCK

Z-value: 1.03

Motif logo

Transcription factors associated with CLOCK

Gene Symbol Gene ID Gene Info
ENSG00000134852.10 clock circadian regulator

Activity profile of CLOCK motif

Sorted Z-values of CLOCK motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_125366089 3.77 ENST00000366139.3
ENST00000278919.3
fasciculation and elongation protein zeta 1 (zygin I)
chr12_-_25102252 3.63 ENST00000261192.7
branched chain amino-acid transaminase 1, cytosolic
chr2_-_216257849 3.55 ENST00000456923.1
fibronectin 1
chr17_+_62223320 3.41 ENST00000580828.1
ENST00000582965.1
small nucleolar RNA, H/ACA box 76
chr1_+_120839412 3.12 ENST00000355228.4
family with sequence similarity 72, member B
chr5_+_135394840 3.11 ENST00000503087.1
transforming growth factor, beta-induced, 68kDa
chr1_-_113498616 3.08 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
solute carrier family 16 (monocarboxylate transporter), member 1
chr6_+_151561506 2.93 ENST00000253332.1
A kinase (PRKA) anchor protein 12
chr18_+_33877654 2.88 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
formin homology 2 domain containing 3
chr11_-_66725837 2.82 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
pyruvate carboxylase
chr11_+_72929319 2.66 ENST00000393597.2
ENST00000311131.2
purinergic receptor P2Y, G-protein coupled, 2
chr11_+_72929402 2.64 ENST00000393596.2
purinergic receptor P2Y, G-protein coupled, 2
chr1_-_26232951 2.63 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr20_+_44441304 2.61 ENST00000352551.5
ubiquitin-conjugating enzyme E2C
chr20_+_44441215 2.60 ENST00000356455.4
ENST00000405520.1
ubiquitin-conjugating enzyme E2C
chr2_-_31361543 2.58 ENST00000349752.5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr16_-_4588762 2.51 ENST00000562334.1
ENST00000562579.1
ENST00000567695.1
ENST00000563507.1
cell death-inducing p53 target 1
chr4_-_103266355 2.50 ENST00000424970.2
solute carrier family 39 (zinc transporter), member 8
chr9_-_123639304 2.50 ENST00000436309.1
PHD finger protein 19
chr15_-_74495188 2.47 ENST00000563965.1
ENST00000395105.4
stimulated by retinoic acid 6
chr16_-_4588822 2.40 ENST00000564828.1
cell death-inducing p53 target 1
chr6_+_151646800 2.39 ENST00000354675.6
A kinase (PRKA) anchor protein 12
chr12_-_25101920 2.35 ENST00000539780.1
ENST00000546285.1
ENST00000342945.5
branched chain amino-acid transaminase 1, cytosolic
chr1_-_111991850 2.33 ENST00000411751.2
WD repeat domain 77
chr1_-_11120057 2.11 ENST00000376957.2
spermidine synthase
chr1_-_26233423 1.97 ENST00000357865.2
stathmin 1
chr4_-_103266626 1.93 ENST00000356736.4
solute carrier family 39 (zinc transporter), member 8
chr20_+_44441271 1.90 ENST00000335046.3
ENST00000243893.6
ubiquitin-conjugating enzyme E2C
chr11_+_69455855 1.87 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr9_-_123639600 1.79 ENST00000373896.3
PHD finger protein 19
chr18_-_33077556 1.78 ENST00000589273.1
ENST00000586489.1
INO80 complex subunit C
chr19_-_49015050 1.78 ENST00000600059.1
lemur tyrosine kinase 3
chr11_+_33037401 1.75 ENST00000241051.3
DEP domain containing 7
chr8_-_95908902 1.72 ENST00000520509.1
cyclin E2
chr2_+_17721230 1.69 ENST00000457525.1
visinin-like 1
chr16_-_4588469 1.61 ENST00000588381.1
ENST00000563332.2
cell death-inducing p53 target 1
chr7_-_142247606 1.58 ENST00000390361.3
T cell receptor beta variable 7-3
chr1_-_111991908 1.58 ENST00000235090.5
WD repeat domain 77
chr1_+_214776516 1.58 ENST00000366955.3
centromere protein F, 350/400kDa
chr9_+_112542572 1.56 ENST00000374530.3
PALM2-AKAP2 readthrough
chr6_+_151561085 1.53 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr2_+_173420697 1.51 ENST00000282077.3
ENST00000392571.2
ENST00000410055.1
pyruvate dehydrogenase kinase, isozyme 1
chr21_-_45079341 1.51 ENST00000443485.1
ENST00000291560.2
heat shock transcription factor 2 binding protein
chr1_+_182992545 1.50 ENST00000258341.4
laminin, gamma 1 (formerly LAMB2)
chr22_+_40390930 1.50 ENST00000333407.6
family with sequence similarity 83, member F
chr6_+_69942298 1.41 ENST00000238918.8
brain-specific angiogenesis inhibitor 3
chr9_-_34637806 1.40 ENST00000477726.1
sigma non-opioid intracellular receptor 1
chr21_-_31869451 1.39 ENST00000334058.2
keratin associated protein 19-4
chr4_+_41258786 1.33 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr8_+_10530133 1.33 ENST00000304519.5
chromosome 8 open reading frame 74
chr3_-_123411191 1.31 ENST00000354792.5
ENST00000508240.1
myosin light chain kinase
chr17_-_38657849 1.30 ENST00000254051.6
tensin 4
chr12_+_57624119 1.29 ENST00000555773.1
ENST00000554975.1
ENST00000449049.3
ENST00000393827.4
serine hydroxymethyltransferase 2 (mitochondrial)
chr19_+_1407733 1.27 ENST00000592453.1
DAZ associated protein 1
chr12_-_58146048 1.26 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chr5_+_110074685 1.24 ENST00000355943.3
ENST00000447245.2
solute carrier family 25, member 46
chr16_+_8814563 1.22 ENST00000425191.2
ENST00000569156.1
4-aminobutyrate aminotransferase
chr12_-_58146128 1.21 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr12_+_57624085 1.21 ENST00000553474.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr4_-_103266219 1.19 ENST00000394833.2
solute carrier family 39 (zinc transporter), member 8
chr6_-_153304697 1.19 ENST00000367241.3
F-box protein 5
chrX_-_51239425 1.18 ENST00000375992.3
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr18_+_12407895 1.18 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
slowmo homolog 1 (Drosophila)
chr2_+_131769256 1.14 ENST00000355771.3
Rho guanine nucleotide exchange factor (GEF) 4
chr3_+_122785895 1.14 ENST00000316218.7
protein disulfide isomerase family A, member 5
chr15_+_81475047 1.12 ENST00000559388.1
interleukin 16
chr22_+_20105259 1.10 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr9_-_130890662 1.10 ENST00000277462.5
ENST00000338961.6
prostaglandin E synthase 2
chr6_-_153304148 1.10 ENST00000229758.3
F-box protein 5
chr2_-_47143160 1.09 ENST00000409800.1
ENST00000409218.1
multiple coagulation factor deficiency 2
chr11_-_64014379 1.09 ENST00000309318.3
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr17_+_46970178 1.08 ENST00000393366.2
ENST00000506855.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr20_+_36012051 1.08 ENST00000373567.2
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr11_-_59952106 1.08 ENST00000529054.1
ENST00000530839.1
membrane-spanning 4-domains, subfamily A, member 6A
chr17_+_17942684 1.08 ENST00000376345.3
GID complex subunit 4
chr2_-_47142884 1.07 ENST00000409105.1
ENST00000409973.1
ENST00000409913.1
ENST00000319466.4
multiple coagulation factor deficiency 2
chr2_+_158114051 1.04 ENST00000259056.4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr12_+_57623477 1.04 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr12_+_57623869 1.04 ENST00000414700.3
ENST00000557703.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr4_+_2814011 1.03 ENST00000502260.1
ENST00000435136.2
SH3-domain binding protein 2
chr7_-_122339162 1.03 ENST00000340112.2
ring finger protein 133
chr5_+_110427983 1.02 ENST00000513710.2
ENST00000505303.1
WD repeat domain 36
chr2_-_220118631 1.01 ENST00000248437.4
tubulin, alpha 4a
chr6_+_41888926 1.01 ENST00000230340.4
bystin-like
chr1_-_205744205 1.01 ENST00000446390.2
RAB7, member RAS oncogene family-like 1
chr6_-_30712313 1.01 ENST00000376377.2
ENST00000259874.5
immediate early response 3
chrX_+_51075658 1.01 ENST00000356450.2
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr19_-_51308175 1.00 ENST00000345523.4
chromosome 19 open reading frame 48
chr17_+_46970127 0.99 ENST00000355938.5
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr14_+_96722539 0.99 ENST00000553356.1
bradykinin receptor B1
chr17_-_40333099 0.99 ENST00000607371.1
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr20_-_6103666 0.98 ENST00000536936.1
fermitin family member 1
chr12_-_122240792 0.98 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
ras homolog family member F (in filopodia)
chr22_-_30987837 0.97 ENST00000335214.6
pescadillo ribosomal biogenesis factor 1
chr3_+_186915274 0.97 ENST00000312295.4
receptor (chemosensory) transporter protein 1
chr3_+_5020801 0.97 ENST00000256495.3
basic helix-loop-helix family, member e40
chr17_+_46970134 0.97 ENST00000503641.1
ENST00000514808.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr9_-_19127474 0.95 ENST00000380465.3
ENST00000380464.3
ENST00000411567.1
ENST00000276914.2
perilipin 2
chr4_+_57302297 0.95 ENST00000399688.3
ENST00000512576.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr9_+_706842 0.95 ENST00000382293.3
KN motif and ankyrin repeat domains 1
chr1_-_53608289 0.94 ENST00000371491.4
solute carrier family 1 (glutamate transporter), member 7
chr2_+_102508955 0.94 ENST00000414004.2
FLJ20373
chr17_+_7210852 0.93 ENST00000576930.1
eukaryotic translation initiation factor 5A
chr19_+_46001697 0.93 ENST00000451287.2
ENST00000324688.4
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr21_-_44299626 0.91 ENST00000330317.2
ENST00000398208.2
WD repeat domain 4
chr1_-_205744574 0.90 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7, member RAS oncogene family-like 1
chr9_-_34637718 0.90 ENST00000378892.1
ENST00000277010.4
sigma non-opioid intracellular receptor 1
chr2_+_55459808 0.89 ENST00000404735.1
ribosomal protein S27a
chr15_-_101835414 0.89 ENST00000254193.6
small nuclear ribonucleoprotein polypeptide A'
chr2_-_106013400 0.88 ENST00000409807.1
four and a half LIM domains 2
chr6_-_43496605 0.87 ENST00000455285.2
exportin 5
chr3_+_99536663 0.86 ENST00000421999.2
ENST00000463526.1
cms1 ribosomal small subunit homolog (yeast)
chr4_+_128651530 0.86 ENST00000281154.4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr18_-_33077942 0.84 ENST00000334598.7
INO80 complex subunit C
chr12_+_71833756 0.84 ENST00000536515.1
ENST00000540815.2
leucine-rich repeat containing G protein-coupled receptor 5
chr11_+_125774362 0.84 ENST00000530414.1
ENST00000530129.2
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr17_+_7210294 0.83 ENST00000336452.7
eukaryotic translation initiation factor 5A
chr2_+_17721920 0.83 ENST00000295156.4
visinin-like 1
chr6_+_31553901 0.83 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
leukocyte specific transcript 1
chr17_+_35732916 0.82 ENST00000586700.1
chromosome 17 open reading frame 78
chr14_+_64854958 0.82 ENST00000555709.2
ENST00000554739.1
ENST00000554768.1
ENST00000216605.8
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr17_+_30813576 0.82 ENST00000313401.3
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr17_+_35732955 0.81 ENST00000300618.4
chromosome 17 open reading frame 78
chr4_-_4291748 0.81 ENST00000452476.1
Ly1 antibody reactive
chr4_-_4291861 0.81 ENST00000343470.4
Ly1 antibody reactive
chr11_+_76494253 0.81 ENST00000333090.4
tsukushi, small leucine rich proteoglycan
chr2_+_201450591 0.80 ENST00000374700.2
aldehyde oxidase 1
chr19_-_51307894 0.80 ENST00000597705.1
ENST00000391812.1
chromosome 19 open reading frame 48
chr17_-_41623716 0.79 ENST00000319349.5
ets variant 4
chr3_+_49209023 0.79 ENST00000332780.2
kelch domain containing 8B
chr22_-_30695471 0.79 ENST00000434291.1
Uncharacterized protein
chr4_+_57301896 0.79 ENST00000514888.1
ENST00000264221.2
ENST00000505164.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr6_-_34113856 0.78 ENST00000538487.2
glutamate receptor, metabotropic 4
chr2_-_50574856 0.78 ENST00000342183.5
neurexin 1
chrX_-_54824673 0.78 ENST00000218436.6
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr19_+_46003056 0.78 ENST00000401593.1
ENST00000396736.2
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr1_+_62439037 0.78 ENST00000545929.1
InaD-like (Drosophila)
chr16_+_28986134 0.77 ENST00000352260.7
spinster homolog 1 (Drosophila)
chr9_+_112542591 0.77 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr16_+_56703737 0.77 ENST00000569155.1
metallothionein 1H
chr17_-_40075219 0.77 ENST00000537919.1
ENST00000352035.2
ENST00000353196.1
ENST00000393896.2
ATP citrate lyase
chr1_+_20617362 0.76 ENST00000375079.2
ENST00000289815.8
ENST00000375083.4
ENST00000289825.4
von Willebrand factor A domain containing 5B1
chr3_-_53878644 0.76 ENST00000481668.1
ENST00000467802.1
choline dehydrogenase
chr3_+_102153859 0.76 ENST00000306176.1
ENST00000466937.1
zona pellucida-like domain containing 1
chr5_+_149737202 0.75 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
Treacher Collins-Franceschetti syndrome 1
chr7_-_92465868 0.75 ENST00000424848.2
cyclin-dependent kinase 6
chr7_-_1781906 0.74 ENST00000453348.1
ENST00000415399.1
AC074389.9
chr8_+_22853345 0.73 ENST00000522948.1
Rho-related BTB domain containing 2
chr6_-_31763721 0.73 ENST00000375663.3
valyl-tRNA synthetase
chr17_-_40333150 0.73 ENST00000264661.3
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr11_+_6866883 0.72 ENST00000299454.4
ENST00000379831.2
olfactory receptor, family 10, subfamily A, member 5
chr4_-_4291761 0.72 ENST00000513174.1
Ly1 antibody reactive
chr1_+_173793777 0.72 ENST00000239457.5
aspartyl-tRNA synthetase 2, mitochondrial
chr15_-_82555000 0.71 ENST00000557844.1
ENST00000359445.3
ENST00000268206.7
elongation factor Tu GTP binding domain containing 1
chr19_-_46974664 0.70 ENST00000438932.2
paraneoplastic Ma antigen family-like 1
chr16_-_81129845 0.70 ENST00000569885.1
ENST00000566566.1
glycine cleavage system protein H (aminomethyl carrier)
chr17_-_48474828 0.70 ENST00000576448.1
ENST00000225972.7
leucine rich repeat containing 59
chr19_+_10765003 0.70 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
interleukin enhancer binding factor 3, 90kDa
chr17_+_48450575 0.70 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
essential meiotic structure-specific endonuclease 1
chr16_+_14980632 0.70 ENST00000565655.1
NODAL modulator 1
chr6_+_7108210 0.69 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
ras responsive element binding protein 1
chr10_+_73156664 0.69 ENST00000398809.4
ENST00000398842.3
ENST00000461841.3
ENST00000299366.7
cadherin-related 23
chr4_-_57301748 0.69 ENST00000264220.2
phosphoribosyl pyrophosphate amidotransferase
chr6_+_7727030 0.69 ENST00000283147.6
bone morphogenetic protein 6
chr19_-_46974741 0.69 ENST00000313683.10
ENST00000602246.1
paraneoplastic Ma antigen family-like 1
chrX_-_128977781 0.68 ENST00000357166.6
zinc finger, DHHC-type containing 9
chr17_-_42908155 0.68 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
gap junction protein, gamma 1, 45kDa
chr15_+_62359175 0.68 ENST00000355522.5
C2 calcium-dependent domain containing 4A
chr17_-_9694614 0.67 ENST00000330255.5
ENST00000571134.1
dehydrogenase/reductase (SDR family) member 7C
chr10_+_70715884 0.67 ENST00000354185.4
DEAD (Asp-Glu-Ala-Asp) box helicase 21
chr4_+_75023816 0.66 ENST00000395759.2
ENST00000331145.6
ENST00000359107.5
ENST00000325278.6
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr14_-_58894332 0.66 ENST00000395159.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr2_+_216176761 0.66 ENST00000540518.1
ENST00000435675.1
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr12_-_114404111 0.66 ENST00000545145.2
ENST00000392561.3
ENST00000261741.5
RNA binding motif protein 19
chr1_-_53608249 0.65 ENST00000371494.4
solute carrier family 1 (glutamate transporter), member 7
chr2_+_238475217 0.65 ENST00000165524.1
prolactin releasing hormone
chr22_-_30987849 0.65 ENST00000402284.3
ENST00000354694.7
pescadillo ribosomal biogenesis factor 1
chr15_-_49447771 0.65 ENST00000558843.1
ENST00000542928.1
ENST00000561248.1
COP9 signalosome subunit 2
chr15_-_49447835 0.65 ENST00000388901.5
ENST00000299259.6
COP9 signalosome subunit 2
chr6_+_7107830 0.65 ENST00000379933.3
ras responsive element binding protein 1
chr2_+_132160448 0.64 ENST00000437751.1
long intergenic non-protein coding RNA 1120
chr7_-_45026200 0.64 ENST00000577700.1
ENST00000580458.1
ENST00000579383.1
ENST00000584686.1
ENST00000585030.1
ENST00000582727.1
small nucleolar RNA host gene 15 (non-protein coding)
chrX_+_15518923 0.64 ENST00000348343.6
BMX non-receptor tyrosine kinase
chr9_-_134145880 0.63 ENST00000372269.3
ENST00000464831.1
family with sequence similarity 78, member A
chr11_+_61957687 0.63 ENST00000306238.3
secretoglobin, family 1D, member 1
chr1_+_117297007 0.63 ENST00000369478.3
ENST00000369477.1
CD2 molecule
chr1_+_38478432 0.62 ENST00000537711.1
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr5_-_150537279 0.62 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
annexin A6
chr16_+_56703703 0.62 ENST00000332374.4
metallothionein 1H
chr4_-_54232144 0.62 ENST00000388940.4
ENST00000503450.1
ENST00000401642.3
sec1 family domain containing 2
chr6_-_144385698 0.62 ENST00000444202.1
ENST00000437412.1
pleiomorphic adenoma gene-like 1
chr1_-_231376836 0.61 ENST00000451322.1
chromosome 1 open reading frame 131
chr14_-_80677970 0.61 ENST00000438257.4
deiodinase, iodothyronine, type II
chr6_-_80657292 0.61 ENST00000369816.4
ELOVL fatty acid elongase 4
chr6_+_31553978 0.61 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
leukocyte specific transcript 1
chr5_+_161274940 0.59 ENST00000393943.4
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chrX_+_16804544 0.59 ENST00000380122.5
ENST00000398155.4
taxilin gamma
chr12_-_104234966 0.59 ENST00000392876.3
5'-nucleotidase domain containing 3
chr18_-_11670159 0.59 ENST00000561598.1
RP11-677O4.2
chr22_+_24990746 0.58 ENST00000456869.1
ENST00000411974.1
gamma-glutamyltransferase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of CLOCK

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
1.0 3.1 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
1.0 6.0 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.9 2.8 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.8 7.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.8 3.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.8 2.3 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.7 4.6 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.7 3.9 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.5 5.6 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.5 2.5 GO:0061143 alveolar primary septum development(GO:0061143)
0.5 6.8 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.4 1.3 GO:0007412 axon target recognition(GO:0007412)
0.4 1.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.4 2.5 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.4 5.3 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.4 1.5 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.4 2.2 GO:1901907 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.4 4.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.4 3.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.3 3.8 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.3 2.4 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.3 1.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.3 0.9 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 1.2 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.3 0.9 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.3 1.4 GO:0015862 uridine transport(GO:0015862)
0.3 0.8 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.3 1.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.3 0.8 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.3 0.8 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.2 2.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 1.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 1.8 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 0.7 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.2 1.5 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.2 1.0 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.2 0.8 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.2 0.8 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 1.0 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.2 0.6 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 2.0 GO:0070141 response to UV-A(GO:0070141)
0.2 2.9 GO:0051639 actin filament network formation(GO:0051639)
0.2 0.9 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.2 0.7 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.2 1.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 0.7 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.2 0.5 GO:0050894 determination of affect(GO:0050894)
0.2 2.4 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 1.6 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.3 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.7 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 1.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.4 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.1 0.7 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.7 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.1 1.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.4 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.5 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.4 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.7 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.4 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 0.6 GO:1902728 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.3 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.1 0.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.3 GO:0032679 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1 0.4 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 0.3 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.8 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.3 GO:0048627 myoblast development(GO:0048627)
0.1 1.6 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.9 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.5 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.4 GO:0035106 operant conditioning(GO:0035106)
0.1 0.8 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 2.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.3 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.4 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 0.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.6 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885) positive regulation of interferon-gamma secretion(GO:1902715)
0.1 0.8 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.2 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.1 0.2 GO:0038178 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 0.8 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.7 GO:0050957 equilibrioception(GO:0050957)
0.1 6.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 1.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 1.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 1.5 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 1.1 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.2 GO:1901165 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.4 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 1.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.6 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.2 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 0.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.2 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.1 0.3 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.7 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.4 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.4 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.4 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.1 0.3 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.2 GO:1904617 regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.0 0.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 1.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.2 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.8 GO:0014029 neural crest formation(GO:0014029)
0.0 0.5 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:1900368 transcription, RNA-templated(GO:0001172) regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 1.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.4 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.7 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.2 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.8 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.4 GO:0000012 single strand break repair(GO:0000012)
0.0 1.5 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.2 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.0 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:0031648 protein destabilization(GO:0031648)
0.0 0.3 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.3 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.8 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.6 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.3 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.0 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0 0.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 1.4 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 1.3 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.5 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 1.4 GO:0007129 synapsis(GO:0007129)
0.0 0.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:1902218 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 1.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 2.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603) positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.0 0.5 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.0 GO:0060168 regulation of adenosine receptor signaling pathway(GO:0060167) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.6 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 1.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 2.0 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.4 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.2 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.6 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.7 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.4 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0070585 protein localization to mitochondrion(GO:0070585)
0.0 0.2 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.4 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.3 GO:0072584 caveolin-mediated endocytosis(GO:0072584)
0.0 1.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.7 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.7 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 3.6 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 1.0 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.3 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.6 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.6 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.0 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 1.0 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.6 GO:0051301 cell division(GO:0051301)
0.0 0.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.6 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.3 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 1.0 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.8 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.2 GO:0007224 smoothened signaling pathway(GO:0007224)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.5 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.6 4.6 GO:0070552 BRISC complex(GO:0070552)
0.4 1.7 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.4 1.7 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.4 2.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.4 1.5 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.3 1.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.3 0.9 GO:0042565 RNA nuclear export complex(GO:0042565)
0.3 0.6 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.3 3.5 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.7 GO:0005960 glycine cleavage complex(GO:0005960)
0.2 1.6 GO:0070545 PeBoW complex(GO:0070545)
0.2 1.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 3.7 GO:0034709 methylosome(GO:0034709)
0.2 0.8 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 7.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 0.7 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 2.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.9 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 0.4 GO:0042022 interleukin-12 receptor complex(GO:0042022)
0.1 0.5 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 1.6 GO:0045120 pronucleus(GO:0045120)
0.1 1.2 GO:0034719 SMN-Sm protein complex(GO:0034719) Gemini of coiled bodies(GO:0097504)
0.1 1.5 GO:0005642 annulate lamellae(GO:0005642)
0.1 4.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 3.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.5 GO:0044308 axonal spine(GO:0044308)
0.1 1.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.3 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.1 0.6 GO:0019815 B cell receptor complex(GO:0019815)
0.1 1.3 GO:0033391 chromatoid body(GO:0033391)
0.1 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.4 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 3.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 2.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.9 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.6 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 2.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.4 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.9 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 4.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 3.2 GO:0005604 basement membrane(GO:0005604)
0.0 1.3 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 0.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.6 GO:0043235 receptor complex(GO:0043235)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 1.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.0 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0005921 gap junction(GO:0005921)
0.0 6.8 GO:0005813 centrosome(GO:0005813)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
1.0 6.0 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.7 2.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.7 4.6 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.5 1.5 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.5 1.4 GO:0004947 bradykinin receptor activity(GO:0004947)
0.4 6.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.4 2.2 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.3 1.0 GO:0017130 poly(C) RNA binding(GO:0017130)
0.3 1.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.3 1.2 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.3 0.9 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.3 2.8 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.3 1.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.3 1.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.3 0.8 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 0.7 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 1.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 2.4 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 0.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.2 1.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 3.7 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.2 1.6 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 0.8 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.2 1.0 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.2 1.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 0.6 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 1.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.2 0.7 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.2 0.5 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 2.4 GO:0004985 opioid receptor activity(GO:0004985)
0.2 0.7 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.2 0.5 GO:0031877 somatostatin receptor binding(GO:0031877)
0.2 0.8 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.7 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 5.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 3.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.1 GO:0071253 connexin binding(GO:0071253)
0.1 0.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.4 GO:0016517 interleukin-12 receptor activity(GO:0016517)
0.1 0.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.8 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.5 GO:0004461 lactose synthase activity(GO:0004461)
0.1 6.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.4 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 6.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.4 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.7 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 1.0 GO:0043426 MRF binding(GO:0043426)
0.1 2.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 4.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 2.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.9 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.9 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 1.8 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.6 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.2 GO:0030984 kininogen binding(GO:0030984)
0.1 0.2 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.3 GO:0004802 transketolase activity(GO:0004802)
0.1 0.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 2.7 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 1.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.8 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.9 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 3.7 GO:0016504 peptidase activator activity(GO:0016504)
0.1 1.9 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 1.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 1.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 1.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.9 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 1.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 3.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 3.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 1.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.6 GO:0043121 neurotrophin binding(GO:0043121)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0000182 rDNA binding(GO:0000182)
0.0 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 2.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.9 GO:0008066 glutamate receptor activity(GO:0008066)
0.0 2.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 1.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.9 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0048365 Rac GTPase binding(GO:0048365)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 4.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.7 ST STAT3 PATHWAY STAT3 Pathway
0.1 4.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 7.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 3.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.9 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID RB 1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.2 5.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 5.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 7.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2 3.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 3.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 4.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 2.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 5.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 2.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 2.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.6 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 1.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 3.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.6 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 1.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.8 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 2.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 2.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 2.3 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 2.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.9 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.9 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 4.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.4 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA