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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for CPEB1

Z-value: 0.80

Motif logo

Transcription factors associated with CPEB1

Gene Symbol Gene ID Gene Info
ENSG00000214575.5 cytoplasmic polyadenylation element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CPEB1hg19_v2_chr15_-_83240507_83240539-0.242.1e-01Click!

Activity profile of CPEB1 motif

Sorted Z-values of CPEB1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_4385230 1.37 ENST00000536537.1
cyclin D2
chr2_-_190044480 1.27 ENST00000374866.3
collagen, type V, alpha 2
chr9_+_105757590 1.09 ENST00000374798.3
ENST00000487798.1
cylicin, basic protein of sperm head cytoskeleton 2
chr13_-_20805109 1.08 ENST00000241124.6
gap junction protein, beta 6, 30kDa
chr16_-_56459354 1.06 ENST00000290649.5
autocrine motility factor receptor, E3 ubiquitin protein ligase
chr6_+_15401075 1.01 ENST00000541660.1
jumonji, AT rich interactive domain 2
chr2_+_114256661 0.99 ENST00000306507.5
forkhead box D4-like 1
chr12_-_91539918 0.99 ENST00000548218.1
decorin
chr4_-_74864386 0.96 ENST00000296027.4
chemokine (C-X-C motif) ligand 5
chr6_-_27114577 0.96 ENST00000356950.1
ENST00000396891.4
histone cluster 1, H2bk
chrX_-_107682702 0.94 ENST00000372216.4
collagen, type IV, alpha 6
chr20_-_10654639 0.94 ENST00000254958.5
jagged 1
chr6_+_12290586 0.91 ENST00000379375.5
endothelin 1
chr4_-_47983519 0.86 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
cyclic nucleotide gated channel alpha 1
chr12_-_52845910 0.85 ENST00000252252.3
keratin 6B
chr8_-_57026541 0.84 ENST00000311923.1
v-mos Moloney murine sarcoma viral oncogene homolog
chr18_-_31802056 0.82 ENST00000538587.1
nucleolar protein 4
chr15_+_45406519 0.82 ENST00000323030.5
dual oxidase maturation factor 2
chr14_-_75079026 0.78 ENST00000261978.4
latent transforming growth factor beta binding protein 2
chr12_-_52715179 0.77 ENST00000293670.3
keratin 83
chr18_+_34124507 0.77 ENST00000591635.1
formin homology 2 domain containing 3
chr11_-_102826434 0.76 ENST00000340273.4
ENST00000260302.3
matrix metallopeptidase 13 (collagenase 3)
chr17_-_39553844 0.75 ENST00000251645.2
keratin 31
chr18_-_31628558 0.75 ENST00000535384.1
nucleolar protein 4
chr14_+_79745746 0.75 ENST00000281127.7
neurexin 3
chr17_-_76220740 0.74 ENST00000600484.1
Uncharacterized protein
chr13_-_103719196 0.72 ENST00000245312.3
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr10_-_105845674 0.70 ENST00000353479.5
ENST00000369733.3
collagen, type XVII, alpha 1
chr3_+_99357319 0.68 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
collagen, type VIII, alpha 1
chr2_-_2334888 0.67 ENST00000428368.2
ENST00000399161.2
myelin transcription factor 1-like
chr15_-_56209306 0.66 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr8_+_85095769 0.65 ENST00000518566.1
RALY RNA binding protein-like
chr3_+_101546827 0.65 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr8_+_85095497 0.64 ENST00000522455.1
ENST00000521695.1
RALY RNA binding protein-like
chr1_-_156675535 0.64 ENST00000368221.1
cellular retinoic acid binding protein 2
chr1_+_84630053 0.63 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_122240792 0.62 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
ras homolog family member F (in filopodia)
chr4_-_116034979 0.61 ENST00000264363.2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr6_+_15246501 0.61 ENST00000341776.2
jumonji, AT rich interactive domain 2
chr1_+_84630645 0.60 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_209848749 0.60 ENST00000367029.4
G0/G1switch 2
chr12_-_91572278 0.60 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
decorin
chr14_+_75746340 0.59 ENST00000555686.1
ENST00000555672.1
FBJ murine osteosarcoma viral oncogene homolog
chr8_+_77593448 0.58 ENST00000521891.2
zinc finger homeobox 4
chr19_+_35634146 0.58 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD domain containing ion transport regulator 7
chr11_-_102651343 0.58 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chr9_+_70917276 0.58 ENST00000342833.2
forkhead box D4-like 3
chr12_-_123201337 0.57 ENST00000528880.2
hydroxycarboxylic acid receptor 3
chr20_-_46415341 0.56 ENST00000484875.1
ENST00000361612.4
sulfatase 2
chr17_-_76921459 0.56 ENST00000262768.7
TIMP metallopeptidase inhibitor 2
chr11_+_35160709 0.55 ENST00000415148.2
ENST00000433354.2
ENST00000449691.2
ENST00000437706.2
ENST00000360158.4
ENST00000428726.2
ENST00000526669.2
ENST00000433892.2
ENST00000278386.6
ENST00000434472.2
ENST00000352818.4
ENST00000442151.2
CD44 molecule (Indian blood group)
chr18_+_29027696 0.54 ENST00000257189.4
desmoglein 3
chr12_-_92536433 0.54 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
chromosome 12 open reading frame 79
chr4_-_52883786 0.54 ENST00000343457.3
leucine rich repeat containing 66
chr12_-_81763184 0.54 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr4_-_74904398 0.54 ENST00000296026.4
chemokine (C-X-C motif) ligand 3
chr7_+_129984630 0.54 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
carboxypeptidase A5
chr7_-_27205136 0.53 ENST00000396345.1
ENST00000343483.6
homeobox A9
chr20_-_46415297 0.53 ENST00000467815.1
ENST00000359930.4
sulfatase 2
chrX_+_100805496 0.53 ENST00000372829.3
armadillo repeat containing, X-linked 1
chr14_+_79745682 0.52 ENST00000557594.1
neurexin 3
chr12_-_96184533 0.52 ENST00000343702.4
ENST00000344911.4
netrin 4
chr12_-_52779433 0.51 ENST00000257951.3
keratin 84
chr5_-_147162263 0.51 ENST00000333010.6
ENST00000265272.5
janus kinase and microtubule interacting protein 2
chr1_-_156675368 0.51 ENST00000368222.3
cellular retinoic acid binding protein 2
chr18_-_31802282 0.50 ENST00000535475.1
nucleolar protein 4
chr9_-_118417 0.50 ENST00000382500.2
forkhead box D4
chr20_+_16729003 0.49 ENST00000246081.2
otoraplin
chr2_+_105050794 0.48 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
long intergenic non-protein coding RNA 1102
chr8_+_70378852 0.48 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
sulfatase 1
chr2_+_210444748 0.48 ENST00000392194.1
microtubule-associated protein 2
chr1_+_26485511 0.48 ENST00000374268.3
family with sequence similarity 110, member D
chr17_-_15244894 0.47 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
tektin 3
chr12_-_81763127 0.47 ENST00000541017.1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr14_-_57277163 0.47 ENST00000555006.1
orthodenticle homeobox 2
chr12_+_41221794 0.47 ENST00000547849.1
contactin 1
chr18_-_35145728 0.46 ENST00000361795.5
ENST00000603232.1
CUGBP, Elav-like family member 4
chr7_-_20826504 0.46 ENST00000418710.2
ENST00000361443.4
Sp8 transcription factor
chr9_+_116263778 0.45 ENST00000394646.3
regulator of G-protein signaling 3
chr9_+_5450503 0.45 ENST00000381573.4
ENST00000381577.3
CD274 molecule
chr9_-_21482312 0.45 ENST00000448696.3
interferon, epsilon
chr17_-_39197699 0.44 ENST00000306271.4
keratin associated protein 1-1
chr1_-_167059830 0.43 ENST00000367868.3
glycoprotein A33 (transmembrane)
chr4_-_111119804 0.43 ENST00000394607.3
ENST00000302274.3
ELOVL fatty acid elongase 6
chr5_-_115910630 0.43 ENST00000343348.6
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr8_+_77593474 0.43 ENST00000455469.2
ENST00000050961.6
zinc finger homeobox 4
chr3_-_141747439 0.43 ENST00000467667.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr11_+_69924397 0.42 ENST00000355303.5
anoctamin 1, calcium activated chloride channel
chr3_-_108248169 0.42 ENST00000273353.3
myosin, heavy chain 15
chr9_+_116263639 0.42 ENST00000343817.5
regulator of G-protein signaling 3
chr9_+_42717234 0.42 ENST00000377590.1
forkhead box D4-like 2
chrX_+_117957741 0.41 ENST00000310164.2
zinc finger, CCHC domain containing 12
chr2_-_228244013 0.41 ENST00000304568.3
transmembrane 4 L six family member 20
chr4_-_65275162 0.41 ENST00000381210.3
ENST00000507440.1
trans-2,3-enoyl-CoA reductase-like
chr11_+_69924639 0.41 ENST00000538023.1
ENST00000398543.2
anoctamin 1, calcium activated chloride channel
chrX_+_135278908 0.41 ENST00000539015.1
ENST00000370683.1
four and a half LIM domains 1
chr20_+_58251716 0.41 ENST00000355648.4
phosphatase and actin regulator 3
chr1_+_214161854 0.40 ENST00000435016.1
prospero homeobox 1
chr5_-_141704566 0.40 ENST00000344120.4
ENST00000434127.2
sprouty homolog 4 (Drosophila)
chr3_-_54962100 0.40 ENST00000273286.5
leucine-rich repeats and transmembrane domains 1
chr14_+_22309368 0.38 ENST00000390433.1
T cell receptor alpha variable 12-1
chr11_-_102714534 0.38 ENST00000299855.5
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr6_+_31683117 0.38 ENST00000375825.3
ENST00000375824.1
lymphocyte antigen 6 complex, locus G6D
chr18_+_22040620 0.37 ENST00000426880.2
histamine receptor H4
chr16_+_11439286 0.37 ENST00000312499.5
ENST00000576027.1
RecQ mediated genome instability 2
chr5_-_27038683 0.37 ENST00000511822.1
ENST00000231021.4
cadherin 9, type 2 (T1-cadherin)
chr1_+_23037323 0.36 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPH receptor B2
chr20_+_58179582 0.36 ENST00000371015.1
ENST00000395639.4
phosphatase and actin regulator 3
chr8_-_143999259 0.36 ENST00000323110.2
cytochrome P450, family 11, subfamily B, polypeptide 2
chr17_-_36358166 0.36 ENST00000537432.1
TBC1 domain family, member 3
chrX_+_135279179 0.35 ENST00000370676.3
four and a half LIM domains 1
chr17_-_38911580 0.35 ENST00000312150.4
keratin 25
chr1_-_200379129 0.35 ENST00000367353.1
zinc finger protein 281
chr19_-_58485895 0.35 ENST00000314391.3
chromosome 19 open reading frame 18
chr2_-_85645545 0.35 ENST00000409275.1
capping protein (actin filament), gelsolin-like
chr2_+_169757750 0.34 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
glucose-6-phosphatase, catalytic, 2
chr1_-_11907829 0.34 ENST00000376480.3
natriuretic peptide A
chr17_-_78450398 0.34 ENST00000306773.4
neuronal pentraxin I
chr1_+_107683644 0.34 ENST00000370067.1
netrin G1
chr7_-_83824169 0.34 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_-_93029865 0.34 ENST00000422361.2
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_221051699 0.34 ENST00000366903.6
H2.0-like homeobox
chr9_-_21995249 0.33 ENST00000494262.1
cyclin-dependent kinase inhibitor 2A
chr12_+_130646999 0.33 ENST00000539839.1
ENST00000229030.4
frizzled family receptor 10
chr8_-_7681411 0.33 ENST00000334773.6
defensin, beta 105A
chr8_+_7345191 0.33 ENST00000335510.6
defensin, beta 105B
chr14_-_57277178 0.32 ENST00000339475.5
ENST00000554559.1
ENST00000555804.1
orthodenticle homeobox 2
chr6_+_21593972 0.32 ENST00000244745.1
ENST00000543472.1
SRY (sex determining region Y)-box 4
chr3_-_37216055 0.32 ENST00000336686.4
leucine rich repeat (in FLII) interacting protein 2
chr7_+_26591441 0.32 ENST00000420912.1
ENST00000457000.1
ENST00000430426.1
AC004947.2
chr18_+_29769978 0.31 ENST00000269202.6
ENST00000581447.1
meprin A, beta
chr4_-_41750922 0.31 ENST00000226382.2
paired-like homeobox 2b
chr11_-_57089671 0.31 ENST00000532437.1
tankyrase 1 binding protein 1, 182kDa
chr9_-_37034028 0.31 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
paired box 5
chr17_+_73780852 0.31 ENST00000589666.1
unkempt family zinc finger
chr2_+_173600514 0.31 ENST00000264111.6
Rap guanine nucleotide exchange factor (GEF) 4
chr17_-_39637392 0.31 ENST00000246639.2
ENST00000393989.1
keratin 35
chr6_+_31105426 0.31 ENST00000547221.1
psoriasis susceptibility 1 candidate 1
chr6_+_41604747 0.30 ENST00000419164.1
ENST00000373051.2
MyoD family inhibitor
chr2_+_173600565 0.30 ENST00000397081.3
Rap guanine nucleotide exchange factor (GEF) 4
chr12_-_52967600 0.30 ENST00000549343.1
ENST00000305620.2
keratin 74
chr15_-_55562479 0.30 ENST00000564609.1
RAB27A, member RAS oncogene family
chr2_+_11679963 0.30 ENST00000263834.5
growth regulation by estrogen in breast cancer 1
chr18_-_60985914 0.29 ENST00000589955.1
B-cell CLL/lymphoma 2
chr7_-_81399411 0.29 ENST00000423064.2
hepatocyte growth factor (hepapoietin A; scatter factor)
chr14_+_103058948 0.29 ENST00000262241.6
REST corepressor 1
chr1_-_32110467 0.29 ENST00000440872.2
ENST00000373703.4
penta-EF-hand domain containing 1
chr6_+_114178512 0.29 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr10_+_133753533 0.29 ENST00000422256.2
protein phosphatase 2, regulatory subunit B, delta
chr9_-_21995300 0.29 ENST00000498628.2
cyclin-dependent kinase inhibitor 2A
chr5_+_140071178 0.28 ENST00000508522.1
ENST00000448069.2
histidyl-tRNA synthetase 2, mitochondrial
chr2_+_192543153 0.28 ENST00000425611.2
nucleic acid binding protein 1
chr3_-_155394152 0.28 ENST00000494598.1
phospholipase C, eta 1
chr4_-_76957214 0.28 ENST00000306621.3
chemokine (C-X-C motif) ligand 11
chr19_+_50191921 0.28 ENST00000420022.3
adrenomedullin 5 (putative)
chr17_-_39646116 0.27 ENST00000328119.6
keratin 36
chr1_+_107683436 0.27 ENST00000370068.1
netrin G1
chr12_-_118797475 0.27 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAO kinase 3
chr2_-_80531399 0.27 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
leucine rich repeat transmembrane neuronal 1
chr17_-_39580775 0.27 ENST00000225550.3
keratin 37
chr2_+_173292390 0.27 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
integrin, alpha 6
chr15_-_55541227 0.27 ENST00000566877.1
RAB27A, member RAS oncogene family
chr3_-_99595037 0.27 ENST00000383694.2
filamin A interacting protein 1-like
chr17_+_45286706 0.26 ENST00000393450.1
ENST00000572303.1
myosin, light chain 4, alkali; atrial, embryonic
chr10_+_17271266 0.26 ENST00000224237.5
vimentin
chr17_+_7211656 0.26 ENST00000416016.2
eukaryotic translation initiation factor 5A
chr18_+_3466248 0.26 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
chr6_-_130543958 0.26 ENST00000437477.2
ENST00000439090.2
sterile alpha motif domain containing 3
chr14_+_37126765 0.26 ENST00000402703.2
paired box 9
chr21_+_17792672 0.26 ENST00000602620.1
long intergenic non-protein coding RNA 478
chr7_+_134551583 0.26 ENST00000435928.1
caldesmon 1
chr12_-_91451758 0.25 ENST00000266719.3
keratocan
chrX_-_154299501 0.25 ENST00000369476.3
ENST00000369484.3
mature T-cell proliferation 1
C-x(9)-C motif containing 4
chr11_-_11374904 0.25 ENST00000528848.2
casein kinase 2, alpha 3 polypeptide
chr3_-_141747459 0.25 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr10_-_104262460 0.25 ENST00000446605.2
ENST00000369905.4
ENST00000545684.1
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr10_+_80008505 0.25 ENST00000434974.1
ENST00000423770.1
ENST00000432742.1
long intergenic non-protein coding RNA 856
chr3_+_40498783 0.25 ENST00000338970.6
ENST00000396203.2
ENST00000416518.1
ribosomal protein L14
chr7_+_28452130 0.25 ENST00000357727.2
cAMP responsive element binding protein 5
chr2_-_211168332 0.25 ENST00000341685.4
myosin, light chain 1, alkali; skeletal, fast
chr10_+_118305435 0.25 ENST00000369221.2
pancreatic lipase
chr10_-_104262426 0.24 ENST00000487599.1
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr7_+_141811539 0.24 ENST00000550469.2
ENST00000477922.3
Putative inactive maltase-glucoamylase-like protein LOC93432
chr4_+_74269956 0.24 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
albumin
chr11_+_112832090 0.24 ENST00000533760.1
neural cell adhesion molecule 1
chr2_+_173292280 0.24 ENST00000264107.7
integrin, alpha 6
chr1_-_168513229 0.24 ENST00000367819.2
chemokine (C motif) ligand 2
chr6_+_26124373 0.24 ENST00000377791.2
ENST00000602637.1
histone cluster 1, H2ac
chr13_+_22245522 0.24 ENST00000382353.5
fibroblast growth factor 9
chr4_+_118955500 0.24 ENST00000296499.5
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr18_-_33702078 0.24 ENST00000586829.1
solute carrier family 39 (zinc transporter), member 6
chr20_+_30193083 0.23 ENST00000376112.3
ENST00000376105.3
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr7_+_39017504 0.23 ENST00000403058.1
POU class 6 homeobox 2
chr6_+_134758827 0.23 ENST00000431422.1
long intergenic non-protein coding RNA 1010
chr7_+_129906660 0.23 ENST00000222481.4
carboxypeptidase A2 (pancreatic)
chr1_-_200379104 0.23 ENST00000367352.3
zinc finger protein 281
chr1_+_116654376 0.23 ENST00000369500.3
mab-21-like 3 (C. elegans)
chr7_-_50860565 0.23 ENST00000403097.1
growth factor receptor-bound protein 10
chr6_+_22146851 0.23 ENST00000606197.1
cancer susceptibility candidate 15 (non-protein coding)
chr4_+_144303093 0.23 ENST00000505913.1
GRB2-associated binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of CPEB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 1.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 0.9 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.3 0.9 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.3 0.8 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.2 0.5 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.9 GO:0097338 response to clozapine(GO:0097338)
0.1 0.5 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.4 GO:2000979 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.6 GO:0048880 sensory system development(GO:0048880)
0.1 0.4 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 0.7 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.2 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 1.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.6 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.8 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 1.0 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.8 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 0.4 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.8 GO:0015705 iodide transport(GO:0015705)
0.1 0.3 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 1.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.7 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 1.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 1.5 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 1.0 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.2 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.3 GO:0035905 N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.6 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 0.3 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.8 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 0.5 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 1.0 GO:0035878 nail development(GO:0035878)
0.1 1.6 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 0.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.5 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 1.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.3 GO:0046098 guanine metabolic process(GO:0046098)
0.1 0.2 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.2 GO:0036269 swimming behavior(GO:0036269)
0.1 0.2 GO:1990637 response to prolactin(GO:1990637)
0.1 0.2 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.5 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.4 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.2 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.6 GO:0009629 response to gravity(GO:0009629)
0.0 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.3 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.2 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.0 0.4 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.2 GO:0061056 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.0 3.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 1.1 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.3 GO:0021546 rhombomere development(GO:0021546) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.3 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.2 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.9 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 4.1 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.3 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.1 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.8 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.2 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.5 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.1 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.9 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1900157 positive regulation of osteoclast proliferation(GO:0090290) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 1.1 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.1 GO:1903978 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) regulation of microglial cell activation(GO:1903978)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0003183 mitral valve morphogenesis(GO:0003183)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.6 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.3 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.3 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.8 GO:0097435 fibril organization(GO:0097435)
0.0 0.6 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.2 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.0 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.4 GO:0000732 strand displacement(GO:0000732)
0.0 0.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.4 GO:1905144 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 1.7 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.3 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.0 GO:0060460 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung development(GO:0060459) left lung morphogenesis(GO:0060460) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.7 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.3 GO:0010458 exit from mitosis(GO:0010458)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.2 0.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 1.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 1.8 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.2 0.5 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 1.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.6 GO:0035976 AP1 complex(GO:0035976)
0.1 0.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 1.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 0.5 GO:0002177 manchette(GO:0002177)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 1.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 1.1 GO:0005922 connexon complex(GO:0005922)
0.0 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 2.1 GO:0000786 nucleosome(GO:0000786)
0.0 2.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0043219 lateral loop(GO:0043219)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.6 GO:1990391 DNA repair complex(GO:1990391)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.3 1.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.9 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 0.5 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.2 1.0 GO:0042835 BRE binding(GO:0042835)
0.2 0.8 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 0.4 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 0.5 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 1.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.3 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.7 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.1 0.6 GO:1990254 keratin filament binding(GO:1990254)
0.1 1.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 1.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.9 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.9 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.5 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.2 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 1.1 GO:0019841 retinol binding(GO:0019841)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 3.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.6 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.0 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 2.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID FGF PATHWAY FGF signaling pathway
0.0 0.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.9 PID IL12 2PATHWAY IL12-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 4.0 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 1.1 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 2.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 2.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters