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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for CREB3L1_CREB3

Z-value: 0.64

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Transcription factors associated with CREB3L1_CREB3

Gene Symbol Gene ID Gene Info
CREB3L1
ENSG00000157613.6 cAMP responsive element binding protein 3 like 1
CREB3
ENSG00000107175.6 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREB3hg19_v2_chr9_+_35732312_35732332-0.301.0e-01Click!
CREB3L1hg19_v2_chr11_+_46299199_46299233-0.242.1e-01Click!

Activity profile of CREB3L1_CREB3 motif

Sorted Z-values of CREB3L1_CREB3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_113498616 2.17 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr1_-_113498943 2.14 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr4_+_75311019 1.84 ENST00000502307.1
AREG
amphiregulin
chr4_+_75310851 1.74 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr12_+_41086297 1.58 ENST00000551295.2
CNTN1
contactin 1
chr9_+_124461603 1.46 ENST00000373782.3
DAB2IP
DAB2 interacting protein
chr6_+_151561085 1.28 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr11_-_64646086 1.27 ENST00000320631.3
EHD1
EH-domain containing 1
chr4_-_122744998 1.13 ENST00000274026.5
CCNA2
cyclin A2
chr19_+_38810447 1.11 ENST00000263372.3
KCNK6
potassium channel, subfamily K, member 6
chr11_+_125495862 1.08 ENST00000428830.2
ENST00000544373.1
ENST00000527013.1
ENST00000526937.1
ENST00000534685.1
CHEK1
checkpoint kinase 1
chr3_-_156272924 1.07 ENST00000467789.1
ENST00000265044.2
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr5_+_94890840 0.98 ENST00000504763.1
ARSK
arylsulfatase family, member K
chr14_+_68086515 0.92 ENST00000261783.3
ARG2
arginase 2
chr1_+_45205478 0.90 ENST00000452259.1
ENST00000372224.4
KIF2C
kinesin family member 2C
chr22_+_38864041 0.90 ENST00000216014.4
ENST00000409006.3
KDELR3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr1_+_45205498 0.89 ENST00000372218.4
KIF2C
kinesin family member 2C
chr19_+_41256764 0.86 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr3_+_100211412 0.83 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
TMEM45A
transmembrane protein 45A
chr7_+_116593953 0.82 ENST00000397750.3
ST7-OT4
ST7 overlapping transcript 4
chr19_-_49015050 0.75 ENST00000600059.1
LMTK3
lemur tyrosine kinase 3
chr5_-_94890648 0.74 ENST00000513823.1
ENST00000514952.1
ENST00000358746.2
TTC37
tetratricopeptide repeat domain 37
chr3_-_156272872 0.72 ENST00000476217.1
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr1_-_119682812 0.70 ENST00000537870.1
WARS2
tryptophanyl tRNA synthetase 2, mitochondrial
chr12_-_113909877 0.69 ENST00000261731.3
LHX5
LIM homeobox 5
chr6_+_24775641 0.68 ENST00000378054.2
ENST00000476555.1
GMNN
geminin, DNA replication inhibitor
chr20_-_1306351 0.62 ENST00000381812.1
SDCBP2
syndecan binding protein (syntenin) 2
chr8_+_22423219 0.62 ENST00000523965.1
ENST00000521554.1
SORBS3
sorbin and SH3 domain containing 3
chr7_-_30066233 0.61 ENST00000222803.5
FKBP14
FK506 binding protein 14, 22 kDa
chr11_+_125496124 0.60 ENST00000533778.2
ENST00000534070.1
CHEK1
checkpoint kinase 1
chr19_-_4670345 0.60 ENST00000599630.1
ENST00000262947.3
C19orf10
chromosome 19 open reading frame 10
chr17_+_7211656 0.59 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr3_-_121468513 0.59 ENST00000494517.1
ENST00000393667.3
GOLGB1
golgin B1
chr20_-_1306391 0.59 ENST00000339987.3
SDCBP2
syndecan binding protein (syntenin) 2
chr2_-_202645612 0.59 ENST00000409632.2
ENST00000410052.1
ENST00000467448.1
ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr15_+_73976715 0.58 ENST00000558689.1
ENST00000560786.2
ENST00000561213.1
ENST00000563584.1
ENST00000561416.1
CD276
CD276 molecule
chr10_-_71930222 0.58 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1A
SAR1 homolog A (S. cerevisiae)
chr6_+_24775153 0.58 ENST00000356509.3
ENST00000230056.3
GMNN
geminin, DNA replication inhibitor
chr2_+_183580954 0.57 ENST00000264065.7
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr3_-_57583185 0.57 ENST00000463880.1
ARF4
ADP-ribosylation factor 4
chr3_-_121468602 0.57 ENST00000340645.5
GOLGB1
golgin B1
chr11_+_69455855 0.57 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr9_+_112542572 0.56 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr12_-_106641728 0.55 ENST00000378026.4
CKAP4
cytoskeleton-associated protein 4
chr3_+_50284321 0.50 ENST00000451956.1
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr6_-_7313381 0.50 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
SSR1
signal sequence receptor, alpha
chr19_+_39903185 0.50 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr8_+_22422749 0.50 ENST00000523900.1
SORBS3
sorbin and SH3 domain containing 3
chr3_-_28390298 0.50 ENST00000457172.1
AZI2
5-azacytidine induced 2
chr19_-_41196534 0.50 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr20_-_35402123 0.49 ENST00000373740.3
ENST00000426836.1
ENST00000373745.3
ENST00000448110.2
ENST00000438549.1
ENST00000447406.1
ENST00000373750.4
ENST00000373734.4
DSN1
DSN1, MIS12 kinetochore complex component
chr19_+_5681153 0.48 ENST00000579559.1
ENST00000577222.1
HSD11B1L
RPL36
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr14_+_24600484 0.47 ENST00000267426.5
FITM1
fat storage-inducing transmembrane protein 1
chr1_-_119683251 0.46 ENST00000369426.5
ENST00000235521.4
WARS2
tryptophanyl tRNA synthetase 2, mitochondrial
chr5_-_114961673 0.46 ENST00000333314.3
TMED7-TICAM2
TMED7-TICAM2 readthrough
chr5_-_131562935 0.45 ENST00000379104.2
ENST00000379100.2
ENST00000428369.1
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr11_-_67407031 0.44 ENST00000335385.3
TBX10
T-box 10
chr5_-_131563501 0.44 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr6_+_116692102 0.42 ENST00000359564.2
DSE
dermatan sulfate epimerase
chr11_-_2906979 0.42 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chrX_+_47441712 0.41 ENST00000218388.4
ENST00000377018.2
ENST00000456754.2
ENST00000377017.1
ENST00000441738.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr7_+_128379449 0.40 ENST00000479257.1
CALU
calumenin
chr16_-_10868853 0.39 ENST00000572428.1
TVP23A
trans-golgi network vesicle protein 23 homolog A (S. cerevisiae)
chr17_+_48450575 0.39 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
EME1
essential meiotic structure-specific endonuclease 1
chr12_-_122750957 0.39 ENST00000451053.2
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr21_-_34960930 0.38 ENST00000437395.1
DONSON
downstream neighbor of SON
chr19_+_16187816 0.38 ENST00000588410.1
TPM4
tropomyosin 4
chr3_-_28390415 0.38 ENST00000414162.1
ENST00000420543.2
AZI2
5-azacytidine induced 2
chr11_+_65686728 0.37 ENST00000312515.2
ENST00000525501.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr11_+_65686802 0.36 ENST00000376991.2
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr19_-_5680891 0.36 ENST00000309324.4
C19orf70
chromosome 19 open reading frame 70
chr17_-_7137857 0.36 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr8_-_29208183 0.36 ENST00000240100.2
DUSP4
dual specificity phosphatase 4
chr19_+_49458107 0.35 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX
BCL2-associated X protein
chr22_+_46476192 0.35 ENST00000443490.1
FLJ27365
hsa-mir-4763
chr10_+_27444268 0.35 ENST00000375940.4
ENST00000342386.6
MASTL
microtubule associated serine/threonine kinase-like
chr11_-_67276100 0.34 ENST00000301488.3
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr7_-_100860851 0.33 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr17_-_7137582 0.32 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chr9_+_101984577 0.32 ENST00000223641.4
SEC61B
Sec61 beta subunit
chr15_+_26360970 0.32 ENST00000556159.1
ENST00000557523.1
LINC00929
long intergenic non-protein coding RNA 929
chr5_+_133984462 0.32 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr1_-_11865982 0.32 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr10_+_26932068 0.32 ENST00000544033.1
ENST00000454991.1
LINC00202-2
RP13-16H11.7
long intergenic non-protein coding RNA 202-2
RP13-16H11.7
chr3_-_28390120 0.31 ENST00000334100.6
AZI2
5-azacytidine induced 2
chr13_+_113951607 0.30 ENST00000397181.3
LAMP1
lysosomal-associated membrane protein 1
chr5_+_176730769 0.30 ENST00000303204.4
ENST00000503216.1
PRELID1
PRELI domain containing 1
chr17_-_7155274 0.30 ENST00000318988.6
ENST00000575783.1
ENST00000573600.1
CTDNEP1
CTD nuclear envelope phosphatase 1
chr16_+_81040794 0.30 ENST00000439957.3
ENST00000393335.3
ENST00000428963.2
ENST00000564669.1
CENPN
centromere protein N
chr4_+_141445311 0.30 ENST00000323570.3
ENST00000511887.2
ELMOD2
ELMO/CED-12 domain containing 2
chr12_+_48722763 0.30 ENST00000335017.1
H1FNT
H1 histone family, member N, testis-specific
chrX_-_46618490 0.30 ENST00000328306.4
SLC9A7
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
chr2_+_192542850 0.29 ENST00000410026.2
NABP1
nucleic acid binding protein 1
chr19_-_41196458 0.28 ENST00000598779.1
NUMBL
numb homolog (Drosophila)-like
chr3_+_133292574 0.28 ENST00000264993.3
CDV3
CDV3 homolog (mouse)
chr1_-_160313025 0.28 ENST00000368069.3
ENST00000241704.7
COPA
coatomer protein complex, subunit alpha
chr6_-_151773232 0.28 ENST00000444024.1
ENST00000367303.4
RMND1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr1_+_44445549 0.28 ENST00000356836.6
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr5_+_68389807 0.28 ENST00000380860.4
ENST00000504103.1
ENST00000502979.1
SLC30A5
solute carrier family 30 (zinc transporter), member 5
chr18_-_46987000 0.28 ENST00000442713.2
ENST00000269445.6
DYM
dymeclin
chr8_+_22423168 0.28 ENST00000518912.1
ENST00000428103.1
SORBS3
sorbin and SH3 domain containing 3
chr22_+_32754139 0.27 ENST00000382088.3
RFPL3
ret finger protein-like 3
chr3_-_57583130 0.26 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr4_-_119757239 0.26 ENST00000280551.6
SEC24D
SEC24 family member D
chr21_+_45138941 0.26 ENST00000398081.1
ENST00000468090.1
ENST00000291565.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr17_-_46716647 0.25 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr19_-_48894104 0.25 ENST00000597017.1
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chrX_-_7895755 0.25 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
PNPLA4
patatin-like phospholipase domain containing 4
chr17_-_7154984 0.25 ENST00000574322.1
CTDNEP1
CTD nuclear envelope phosphatase 1
chr14_+_78227105 0.25 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
C14orf178
chromosome 14 open reading frame 178
chr15_+_40987327 0.25 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
RAD51
RAD51 recombinase
chr21_+_44313375 0.24 ENST00000354250.2
ENST00000340344.4
NDUFV3
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr9_+_126777676 0.24 ENST00000488674.2
LHX2
LIM homeobox 2
chr19_-_47164386 0.24 ENST00000391916.2
ENST00000410105.2
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr12_+_113376249 0.24 ENST00000551007.1
ENST00000548514.1
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr19_-_46916805 0.23 ENST00000307522.3
CCDC8
coiled-coil domain containing 8
chr17_+_40688190 0.23 ENST00000225927.2
NAGLU
N-acetylglucosaminidase, alpha
chr15_-_23692381 0.23 ENST00000567107.1
ENST00000345070.5
ENST00000312015.5
GOLGA6L2
golgin A6 family-like 2
chr1_-_43833628 0.23 ENST00000413844.2
ENST00000372458.3
ELOVL1
ELOVL fatty acid elongase 1
chr1_-_11866034 0.23 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_+_26758790 0.23 ENST00000427245.2
ENST00000525682.2
ENST00000236342.7
ENST00000526219.1
ENST00000374185.3
ENST00000360009.2
DHDDS
dehydrodolichyl diphosphate synthase
chr3_-_113465065 0.23 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr3_+_122785895 0.22 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr22_+_32753854 0.22 ENST00000249007.4
RFPL3
ret finger protein-like 3
chr2_-_220042825 0.22 ENST00000409789.1
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr15_-_40213080 0.22 ENST00000561100.1
GPR176
G protein-coupled receptor 176
chr13_+_113951532 0.22 ENST00000332556.4
LAMP1
lysosomal-associated membrane protein 1
chr2_+_219745020 0.22 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr5_-_114961858 0.22 ENST00000282382.4
ENST00000456936.3
ENST00000408996.4
TMED7-TICAM2
TMED7
TICAM2
TMED7-TICAM2 readthrough
transmembrane emp24 protein transport domain containing 7
toll-like receptor adaptor molecule 2
chr16_+_56642041 0.22 ENST00000245185.5
MT2A
metallothionein 2A
chr10_+_64893039 0.22 ENST00000277746.6
ENST00000435510.2
NRBF2
nuclear receptor binding factor 2
chr5_-_39425290 0.22 ENST00000545653.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr16_-_2059748 0.22 ENST00000562103.1
ENST00000431526.1
ZNF598
zinc finger protein 598
chr7_+_39663061 0.21 ENST00000005257.2
RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
chr11_+_66188475 0.21 ENST00000311034.2
NPAS4
neuronal PAS domain protein 4
chr2_-_80531399 0.21 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr5_+_94890778 0.21 ENST00000380009.4
ARSK
arylsulfatase family, member K
chr2_-_130886795 0.21 ENST00000409914.2
POTEF
POTE ankyrin domain family, member F
chr8_-_144623595 0.21 ENST00000262577.5
ZC3H3
zinc finger CCCH-type containing 3
chr8_-_57906362 0.21 ENST00000262644.4
IMPAD1
inositol monophosphatase domain containing 1
chr5_-_138210977 0.21 ENST00000274711.6
ENST00000521094.2
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr6_-_101329157 0.21 ENST00000369143.2
ASCC3
activating signal cointegrator 1 complex subunit 3
chr16_+_56642489 0.21 ENST00000561491.1
MT2A
metallothionein 2A
chr2_-_80531824 0.21 ENST00000295057.3
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr2_+_28615669 0.21 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr1_-_202311088 0.21 ENST00000367274.4
UBE2T
ubiquitin-conjugating enzyme E2T (putative)
chr4_-_83350580 0.20 ENST00000349655.4
ENST00000602300.1
HNRNPDL
heterogeneous nuclear ribonucleoprotein D-like
chr19_+_531713 0.20 ENST00000215574.4
CDC34
cell division cycle 34
chr1_+_55271736 0.20 ENST00000358193.3
ENST00000371273.3
C1orf177
chromosome 1 open reading frame 177
chr19_-_18391708 0.20 ENST00000600972.1
JUND
jun D proto-oncogene
chr9_-_136242956 0.20 ENST00000371989.3
ENST00000485435.2
SURF4
surfeit 4
chr5_-_39425222 0.19 ENST00000320816.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr9_+_131709966 0.19 ENST00000372577.2
NUP188
nucleoporin 188kDa
chr5_+_109025067 0.19 ENST00000261483.4
MAN2A1
mannosidase, alpha, class 2A, member 1
chr17_-_6554877 0.19 ENST00000225728.3
ENST00000575197.1
MED31
mediator complex subunit 31
chr5_-_172198190 0.19 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr6_-_90062543 0.18 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr7_+_128379346 0.18 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr16_+_2059872 0.18 ENST00000567649.1
NPW
neuropeptide W
chr22_+_21271714 0.18 ENST00000354336.3
CRKL
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr12_-_50616382 0.18 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr19_-_15236173 0.18 ENST00000527093.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr19_+_797392 0.17 ENST00000350092.4
ENST00000349038.4
ENST00000586481.1
ENST00000585535.1
PTBP1
polypyrimidine tract binding protein 1
chr1_-_32110467 0.17 ENST00000440872.2
ENST00000373703.4
PEF1
penta-EF-hand domain containing 1
chr19_-_10341948 0.17 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
S1PR2
DNMT1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr15_+_84904525 0.17 ENST00000510439.2
GOLGA6L4
golgin A6 family-like 4
chr7_+_150929550 0.17 ENST00000482173.1
ENST00000495645.1
ENST00000035307.2
CHPF2
chondroitin polymerizing factor 2
chr10_-_22292675 0.17 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr10_+_75504105 0.17 ENST00000535742.1
ENST00000546025.1
ENST00000345254.4
ENST00000540668.1
ENST00000339365.2
ENST00000411652.2
SEC24C
SEC24 family member C
chr1_-_206945830 0.17 ENST00000423557.1
IL10
interleukin 10
chr11_-_68039364 0.16 ENST00000533310.1
ENST00000304271.6
ENST00000527280.1
C11orf24
chromosome 11 open reading frame 24
chr3_+_19988885 0.16 ENST00000422242.1
RAB5A
RAB5A, member RAS oncogene family
chr10_-_27444143 0.16 ENST00000477432.1
YME1L1
YME1-like 1 ATPase
chr12_-_50616122 0.16 ENST00000552823.1
ENST00000552909.1
LIMA1
LIM domain and actin binding 1
chr20_+_57267669 0.16 ENST00000356091.6
NPEPL1
aminopeptidase-like 1
chr6_+_26020672 0.16 ENST00000357647.3
HIST1H3A
histone cluster 1, H3a
chr17_-_48450534 0.16 ENST00000503633.1
ENST00000442592.3
ENST00000225969.4
MRPL27
mitochondrial ribosomal protein L27
chr19_+_797443 0.16 ENST00000394601.4
ENST00000589575.1
PTBP1
polypyrimidine tract binding protein 1
chr1_+_119911425 0.15 ENST00000361035.4
ENST00000325945.3
HAO2
hydroxyacid oxidase 2 (long chain)
chr1_+_11866270 0.15 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
CLCN6
chloride channel, voltage-sensitive 6
chr5_-_39425068 0.15 ENST00000515700.1
ENST00000339788.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr12_+_4918342 0.15 ENST00000280684.3
ENST00000433855.1
KCNA6
potassium voltage-gated channel, shaker-related subfamily, member 6
chr3_+_132378741 0.15 ENST00000493720.2
UBA5
ubiquitin-like modifier activating enzyme 5
chr19_-_41256207 0.15 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
C19orf54
chromosome 19 open reading frame 54
chr11_-_65624415 0.15 ENST00000524553.1
ENST00000527344.1
CFL1
cofilin 1 (non-muscle)
chr1_+_228327923 0.15 ENST00000391865.3
GUK1
guanylate kinase 1
chr3_-_4508925 0.15 ENST00000534863.1
ENST00000383843.5
ENST00000458465.2
ENST00000405420.2
ENST00000272902.5
SUMF1
sulfatase modifying factor 1
chr20_+_18118703 0.15 ENST00000464792.1
CSRP2BP
CSRP2 binding protein
chr1_+_228327943 0.15 ENST00000366726.1
ENST00000312726.4
ENST00000366728.2
ENST00000453943.1
ENST00000366723.1
ENST00000366722.1
ENST00000435153.1
ENST00000366721.1
GUK1
guanylate kinase 1
chr7_+_100271446 0.14 ENST00000419828.1
ENST00000427895.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr5_-_176730676 0.14 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24
RAB24, member RAS oncogene family
chr12_+_41086215 0.14 ENST00000547702.1
ENST00000551424.1
CNTN1
contactin 1
chr3_-_57583052 0.14 ENST00000496292.1
ENST00000489843.1
ARF4
ADP-ribosylation factor 4
chr8_-_125384927 0.14 ENST00000297632.6
TMEM65
transmembrane protein 65
chr6_+_63921351 0.14 ENST00000370659.1
FKBP1C
FK506 binding protein 1C
chr12_-_56320887 0.14 ENST00000398213.4
WIBG
within bgcn homolog (Drosophila)
chr4_+_25235597 0.14 ENST00000264864.6
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr2_+_171785824 0.14 ENST00000452526.2
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr6_-_101329191 0.14 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
ASCC3
activating signal cointegrator 1 complex subunit 3
chrX_-_7895479 0.14 ENST00000381042.4
PNPLA4
patatin-like phospholipase domain containing 4

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L1_CREB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.4 3.6 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.4 1.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.3 1.5 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.3 0.8 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.3 1.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 1.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 1.3 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.2 1.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 1.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 0.7 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.6 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 0.5 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.4 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.3 GO:1903519 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1 0.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.5 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.2 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 1.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.7 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.4 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 1.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.3 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.4 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 1.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.9 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.8 GO:0007135 meiosis II(GO:0007135)
0.1 0.2 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.6 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.3 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.1 0.2 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.9 GO:0000050 urea cycle(GO:0000050)
0.1 0.3 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 0.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.6 GO:0070141 response to UV-A(GO:0070141)
0.1 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.3 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.4 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.6 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.9 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.3 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.9 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.2 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.5 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 1.8 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.1 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:2000784 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 2.8 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.5 GO:0048070 regulation of developmental pigmentation(GO:0048070)
0.0 1.4 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 0.2 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.5 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.2 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.0 GO:0035993 subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.1 GO:0032418 lysosome localization(GO:0032418)
0.0 0.0 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.0 GO:1903121 central nervous system myelin maintenance(GO:0032286) regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:2000767 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.0 GO:1903371 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1990032 parallel fiber(GO:1990032)
0.4 1.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.3 1.3 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 0.7 GO:0055087 Ski complex(GO:0055087)
0.2 0.5 GO:0000818 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.1 0.5 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.5 GO:0032010 phagolysosome(GO:0032010)
0.1 0.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 3.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.6 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 1.8 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.9 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.6 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 1.6 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.3 1.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 1.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 1.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 1.8 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 1.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.9 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.9 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.3 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.3 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.4 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 1.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.3 GO:0004461 lactose synthase activity(GO:0004461)
0.1 4.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.4 GO:0017166 vinculin binding(GO:0017166)
0.1 1.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.2 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.2 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.4 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.6 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 1.8 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0098811 RNA polymerase II transcription coactivator activity(GO:0001105) transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.0 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.8 PID AURORA B PATHWAY Aurora B signaling
0.0 1.9 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.5 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.8 REACTOME KINESINS Genes involved in Kinesins
0.0 1.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 2.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 2.7 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks