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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for DBP

Z-value: 0.63

Motif logo

Transcription factors associated with DBP

Gene Symbol Gene ID Gene Info
ENSG00000105516.6 D-box binding PAR bZIP transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DBPhg19_v2_chr19_-_49137762_49137783-0.173.8e-01Click!

Activity profile of DBP motif

Sorted Z-values of DBP motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_112564797 1.77 ENST00000398214.1
ENST00000448932.1
CD200 receptor 1-like
chr4_-_23891693 1.54 ENST00000264867.2
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr1_+_104293028 1.41 ENST00000370079.3
amylase, alpha 1C (salivary)
chr8_+_99076750 1.22 ENST00000545282.1
chromosome 8 open reading frame 47
chr15_+_71228826 1.21 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
leucine rich repeat containing 49
chr1_+_104159999 1.20 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr10_+_115511213 1.18 ENST00000361048.1
pleckstrin homology domain containing, family S member 1
chr8_+_99076509 1.13 ENST00000318528.3
chromosome 8 open reading frame 47
chr1_+_61547405 1.13 ENST00000371189.4
nuclear factor I/A
chr9_-_89562104 1.06 ENST00000298743.7
growth arrest-specific 1
chr3_+_141105705 1.04 ENST00000513258.1
zinc finger and BTB domain containing 38
chrX_-_10851762 0.98 ENST00000380785.1
ENST00000380787.1
midline 1 (Opitz/BBB syndrome)
chr13_+_97928395 0.89 ENST00000445661.2
muscleblind-like splicing regulator 2
chr2_-_216257849 0.74 ENST00000456923.1
fibronectin 1
chr16_+_78056412 0.72 ENST00000299642.4
ENST00000575655.1
C-type lectin domain family 3, member A
chr5_-_124080203 0.70 ENST00000504926.1
zinc finger protein 608
chr13_+_31506818 0.64 ENST00000380473.3
testis expressed 26
chr3_-_114343768 0.61 ENST00000393785.2
zinc finger and BTB domain containing 20
chr1_-_227505289 0.59 ENST00000366765.3
CDC42 binding protein kinase alpha (DMPK-like)
chr1_-_40367668 0.58 ENST00000397332.2
ENST00000429311.1
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr3_+_140947563 0.58 ENST00000505013.1
acid phosphatase-like 2
chr15_-_27018175 0.57 ENST00000311550.5
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr1_+_61547894 0.54 ENST00000403491.3
nuclear factor I/A
chr20_+_51588873 0.54 ENST00000371497.5
teashirt zinc finger homeobox 2
chr3_-_50541028 0.54 ENST00000266039.3
ENST00000435965.1
ENST00000395083.1
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr3_+_109128837 0.53 ENST00000497996.1
RP11-702L6.4
chr17_+_72426891 0.52 ENST00000392627.1
G protein-coupled receptor, family C, group 5, member C
chr5_-_111091948 0.51 ENST00000447165.2
neuronal regeneration related protein
chr16_+_89724188 0.51 ENST00000301031.4
ENST00000566204.1
ENST00000579310.1
spermatogenesis associated 33
chr8_-_102803163 0.50 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
neurocalcin delta
chr19_+_13134772 0.50 ENST00000587760.1
ENST00000585575.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr7_+_114055052 0.49 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
forkhead box P2
chr16_+_67022476 0.48 ENST00000540947.2
carboxylesterase 4A
chr16_+_67022633 0.48 ENST00000398354.1
ENST00000326686.5
carboxylesterase 4A
chr16_+_67022582 0.48 ENST00000541479.1
ENST00000338718.4
carboxylesterase 4A
chr4_-_105416039 0.47 ENST00000394767.2
CXXC finger protein 4
chr10_+_104178946 0.47 ENST00000432590.1
F-box and leucine-rich repeat protein 15
chr2_-_118943930 0.46 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
chr3_-_50540854 0.46 ENST00000423994.2
ENST00000424201.2
ENST00000479441.1
ENST00000429770.1
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr13_+_97874574 0.46 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
muscleblind-like splicing regulator 2
chr3_+_88108381 0.45 ENST00000473136.1
Uncharacterized protein
chrX_+_129473859 0.45 ENST00000424447.1
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr5_-_27038683 0.45 ENST00000511822.1
ENST00000231021.4
cadherin 9, type 2 (T1-cadherin)
chr1_+_211433275 0.43 ENST00000367005.4
REST corepressor 3
chr12_-_89918522 0.43 ENST00000529983.2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr10_-_104178857 0.42 ENST00000020673.5
pleckstrin and Sec7 domain containing
chr20_-_21378666 0.40 ENST00000351817.4
NK2 homeobox 4
chr2_-_152830479 0.40 ENST00000360283.6
calcium channel, voltage-dependent, beta 4 subunit
chr1_+_61548225 0.39 ENST00000371187.3
nuclear factor I/A
chr7_+_145813453 0.39 ENST00000361727.3
contactin associated protein-like 2
chr3_+_123813543 0.39 ENST00000360013.3
kalirin, RhoGEF kinase
chr17_+_2240916 0.38 ENST00000574563.1
small G protein signaling modulator 2
chr6_-_56819385 0.38 ENST00000370754.5
ENST00000449297.2
dystonin
chr13_-_67802549 0.37 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr12_+_18891045 0.37 ENST00000317658.3
capping protein (actin filament) muscle Z-line, alpha 3
chr11_+_121461097 0.36 ENST00000527934.1
sortilin-related receptor, L(DLR class) A repeats containing
chr20_-_14318248 0.36 ENST00000378053.3
ENST00000341420.4
fibronectin leucine rich transmembrane protein 3
chr12_+_7169887 0.36 ENST00000542978.1
complement component 1, s subcomponent
chr19_+_13135386 0.35 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr6_+_33168637 0.35 ENST00000374677.3
solute carrier family 39 (zinc transporter), member 7
chr6_+_33168597 0.34 ENST00000374675.3
solute carrier family 39 (zinc transporter), member 7
chr14_+_51026743 0.34 ENST00000358385.6
ENST00000357032.3
ENST00000354525.4
atlastin GTPase 1
chr17_+_79953310 0.34 ENST00000582355.2
alveolar soft part sarcoma chromosome region, candidate 1
chr1_-_108231101 0.33 ENST00000544443.1
ENST00000415432.2
vav 3 guanine nucleotide exchange factor
chr11_+_93063137 0.33 ENST00000534747.1
coiled-coil domain containing 67
chr16_-_18468926 0.33 ENST00000545114.1
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr13_-_41593425 0.31 ENST00000239882.3
E74-like factor 1 (ets domain transcription factor)
chr2_-_96701722 0.31 ENST00000434632.1
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr22_-_31742218 0.30 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
POZ (BTB) and AT hook containing zinc finger 1
chr3_-_114343039 0.30 ENST00000481632.1
zinc finger and BTB domain containing 20
chrX_-_100641155 0.29 ENST00000372880.1
ENST00000308731.7
Bruton agammaglobulinemia tyrosine kinase
chr3_+_184098065 0.29 ENST00000348986.3
chordin
chr3_-_23958402 0.29 ENST00000415901.2
ENST00000416026.2
ENST00000412028.1
ENST00000388759.3
ENST00000437230.1
NFKB inhibitor interacting Ras-like 1
chr7_-_50633078 0.28 ENST00000444124.2
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr3_+_141106458 0.28 ENST00000509883.1
zinc finger and BTB domain containing 38
chr3_+_184097905 0.27 ENST00000450923.1
chordin
chr14_+_76452090 0.27 ENST00000314067.6
ENST00000238628.6
ENST00000556742.1
intraflagellar transport 43 homolog (Chlamydomonas)
chr1_+_87797351 0.27 ENST00000370542.1
LIM domain only 4
chr14_-_21562648 0.27 ENST00000555270.1
zinc finger protein 219
chr2_+_95963052 0.27 ENST00000295225.5
Kv channel interacting protein 3, calsenilin
chr8_-_40755333 0.26 ENST00000297737.6
ENST00000315769.7
zinc finger, matrin-type 4
chr16_+_19183671 0.26 ENST00000562711.2
synaptotagmin XVII
chr4_-_123542224 0.26 ENST00000264497.3
interleukin 21
chr12_-_57037284 0.26 ENST00000551570.1
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr3_+_184097836 0.25 ENST00000204604.1
ENST00000310236.3
chordin
chr5_-_139422654 0.25 ENST00000289409.4
ENST00000358522.3
ENST00000378238.4
ENST00000289422.7
ENST00000361474.1
ENST00000545385.1
ENST00000394770.1
ENST00000541337.1
neuregulin 2
chr2_-_60780607 0.25 ENST00000537768.1
ENST00000335712.6
ENST00000356842.4
B-cell CLL/lymphoma 11A (zinc finger protein)
chr2_-_88427568 0.25 ENST00000393750.3
ENST00000295834.3
fatty acid binding protein 1, liver
chr17_-_7232585 0.25 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
neuralized E3 ubiquitin protein ligase 4
chr1_-_23886285 0.25 ENST00000374561.5
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr2_+_135011731 0.24 ENST00000281923.2
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr4_-_142199943 0.24 ENST00000514347.1
RP11-586L23.1
chr13_+_93879085 0.24 ENST00000377047.4
glypican 6
chr17_+_26369865 0.24 ENST00000582037.1
nemo-like kinase
chr20_-_18447667 0.23 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
double zinc ribbon and ankyrin repeat domains 1
chr11_-_30038490 0.23 ENST00000328224.6
potassium voltage-gated channel, shaker-related subfamily, member 4
chr10_+_695888 0.23 ENST00000441152.2
proline rich 26
chr14_-_92413353 0.23 ENST00000556154.1
fibulin 5
chr11_+_35684288 0.23 ENST00000299413.5
tripartite motif containing 44
chr3_+_69812877 0.23 ENST00000457080.1
ENST00000328528.6
microphthalmia-associated transcription factor
chr8_-_17533838 0.22 ENST00000400046.1
microtubule associated tumor suppressor 1
chr3_+_137483579 0.22 ENST00000306087.1
SRY (sex determining region Y)-box 14
chr15_+_34261089 0.22 ENST00000383263.5
cholinergic receptor, muscarinic 5
chr4_-_157892167 0.22 ENST00000541126.1
platelet derived growth factor C
chr3_+_69812701 0.21 ENST00000472437.1
microphthalmia-associated transcription factor
chr16_+_25228242 0.21 ENST00000219660.5
aquaporin 8
chr16_+_30675654 0.20 ENST00000287468.5
ENST00000395073.2
fibrosin
chr9_+_2158443 0.20 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_-_157892055 0.20 ENST00000422544.2
platelet derived growth factor C
chr7_+_35756186 0.20 ENST00000430518.1
AC018647.3
chr1_-_85870177 0.19 ENST00000542148.1
dimethylarginine dimethylaminohydrolase 1
chr5_+_129083772 0.19 ENST00000564719.1
KIAA1024-like
chr6_+_7389694 0.19 ENST00000379834.2
RIO kinase 1
chr4_+_160188889 0.19 ENST00000264431.4
Rap guanine nucleotide exchange factor (GEF) 2
chr7_+_103969104 0.19 ENST00000424859.1
ENST00000535008.1
ENST00000401970.2
ENST00000543266.1
lipoma HMGIC fusion partner-like 3
chr9_+_2158485 0.19 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_-_74088800 0.19 ENST00000509867.2
ankyrin repeat domain 17
chr1_+_203734296 0.19 ENST00000442561.2
ENST00000367217.5
lymphocyte transmembrane adaptor 1
chr10_+_102222798 0.18 ENST00000343737.5
wingless-type MMTV integration site family, member 8B
chr2_-_211036051 0.18 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KAT8 regulatory NSL complex subunit 1-like
chr17_+_7487146 0.18 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
mannose-P-dolichol utilization defect 1
chr8_+_19796381 0.18 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
lipoprotein lipase
chr12_-_6483969 0.18 ENST00000396966.2
sodium channel, non-voltage-gated 1 alpha subunit
chr19_+_39881951 0.18 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
mediator complex subunit 29
chr5_-_58295712 0.18 ENST00000317118.8
phosphodiesterase 4D, cAMP-specific
chr2_-_69180012 0.18 ENST00000481498.1
gastrokine 2
chrX_+_129473916 0.17 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr8_-_29120580 0.17 ENST00000524189.1
kinesin family member 13B
chr17_+_4613776 0.17 ENST00000269260.2
arrestin, beta 2
chr11_+_64009072 0.17 ENST00000535135.1
ENST00000394540.3
FK506 binding protein 2, 13kDa
chr17_-_34195862 0.17 ENST00000592980.1
ENST00000587626.1
chromosome 17 open reading frame 66
chr17_-_34195889 0.16 ENST00000311880.2
chromosome 17 open reading frame 66
chr16_+_67226019 0.16 ENST00000379378.3
E2F transcription factor 4, p107/p130-binding
chr17_+_4613918 0.16 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
arrestin, beta 2
chr20_+_60718785 0.16 ENST00000421564.1
ENST00000450482.1
ENST00000331758.3
synovial sarcoma translocation gene on chromosome 18-like 1
chr18_-_21891460 0.16 ENST00000357041.4
oxysterol binding protein-like 1A
chr6_+_53976285 0.16 ENST00000514433.1
muscular LMNA-interacting protein
chr19_+_10765699 0.16 ENST00000590009.1
interleukin enhancer binding factor 3, 90kDa
chr1_+_167298281 0.15 ENST00000367862.5
POU class 2 homeobox 1
chrX_-_24045303 0.15 ENST00000328046.8
kelch-like family member 15
chr4_-_76555657 0.15 ENST00000307465.4
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr6_-_31514333 0.15 ENST00000376151.4
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr9_-_13165457 0.15 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
multiple PDZ domain protein
chr2_+_169658928 0.15 ENST00000317647.7
ENST00000445023.2
nitric oxide synthase trafficking
chr17_+_28705921 0.15 ENST00000225719.4
carboxypeptidase D
chr17_+_2240775 0.14 ENST00000268989.3
ENST00000426855.2
small G protein signaling modulator 2
chr17_+_48823896 0.14 ENST00000511974.1
LUC7-like 3 (S. cerevisiae)
chr4_-_157892498 0.14 ENST00000502773.1
platelet derived growth factor C
chr3_+_141043050 0.14 ENST00000509842.1
zinc finger and BTB domain containing 38
chr6_-_31514516 0.14 ENST00000303892.5
ENST00000483251.1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr3_+_140396881 0.14 ENST00000286349.3
tripartite motif containing 42
chr3_-_88108212 0.14 ENST00000482016.1
CGG triplet repeat binding protein 1
chr9_+_139886846 0.14 ENST00000371620.3
chromosome 9 open reading frame 142
chr2_+_169659121 0.14 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
nitric oxide synthase trafficking
chr5_+_161494521 0.13 ENST00000356592.3
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr1_-_40367530 0.13 ENST00000372816.2
ENST00000372815.1
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr17_+_48624450 0.13 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
spermatogenesis associated 20
chr19_+_19496728 0.13 ENST00000537887.1
ENST00000417582.2
GATA zinc finger domain containing 2A
chrX_-_83442915 0.13 ENST00000262752.2
ENST00000543399.1
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr17_-_27333311 0.13 ENST00000317338.12
ENST00000585644.1
seizure related 6 homolog (mouse)
chr7_+_99613212 0.13 ENST00000426572.1
ENST00000535170.1
zinc finger with KRAB and SCAN domains 1
chr2_-_111291587 0.13 ENST00000437167.1
RANBP2-like and GRIP domain containing 6
chr6_-_94129244 0.12 ENST00000369303.4
ENST00000369297.1
EPH receptor A7
chr9_-_139371533 0.12 ENST00000290037.6
ENST00000431893.2
ENST00000371706.3
SEC16 homolog A (S. cerevisiae)
chr10_+_60936921 0.12 ENST00000373878.3
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr11_-_122931881 0.12 ENST00000526110.1
ENST00000227378.3
heat shock 70kDa protein 8
chr9_-_112083229 0.12 ENST00000374566.3
ENST00000374557.4
erythrocyte membrane protein band 4.1 like 4B
chr17_-_27333163 0.12 ENST00000360295.9
seizure related 6 homolog (mouse)
chr2_-_69180083 0.12 ENST00000328895.4
gastrokine 2
chr5_-_142780280 0.12 ENST00000424646.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chrX_+_23801280 0.12 ENST00000379251.3
ENST00000379253.3
ENST00000379254.1
ENST00000379270.4
spermidine/spermine N1-acetyltransferase 1
chr16_-_75282088 0.12 ENST00000542031.2
breast cancer anti-estrogen resistance 1
chrX_+_91034260 0.12 ENST00000395337.2
protocadherin 11 X-linked
chr2_+_169757750 0.11 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
glucose-6-phosphatase, catalytic, 2
chr5_+_73109339 0.11 ENST00000296799.4
Rho guanine nucleotide exchange factor (GEF) 28
chr10_-_64576105 0.11 ENST00000242480.3
ENST00000411732.1
early growth response 2
chr3_-_48471454 0.11 ENST00000296440.6
ENST00000448774.2
plexin B1
chr3_-_47023455 0.11 ENST00000446836.1
ENST00000425441.1
coiled-coil domain containing 12
chr14_+_24590560 0.11 ENST00000558325.1
RP11-468E2.6
chr17_+_42429493 0.11 ENST00000586242.1
granulin
chr22_+_42196666 0.11 ENST00000402061.3
ENST00000255784.5
coiled-coil domain containing 134
chr4_-_176733897 0.11 ENST00000393658.2
glycoprotein M6A
chr17_+_29664830 0.11 ENST00000444181.2
ENST00000417592.2
neurofibromin 1
chr5_+_72143988 0.11 ENST00000506351.2
transportin 1
chr7_+_142880512 0.11 ENST00000446620.1
taste receptor, type 2, member 39
chr10_-_17171817 0.11 ENST00000377833.4
cubilin (intrinsic factor-cobalamin receptor)
chr9_-_95186739 0.11 ENST00000375550.4
osteomodulin
chr6_-_86352982 0.11 ENST00000369622.3
synaptotagmin binding, cytoplasmic RNA interacting protein
chr4_-_16900184 0.10 ENST00000515064.1
LIM domain binding 2
chr1_+_223101757 0.10 ENST00000284476.6
dispatched homolog 1 (Drosophila)
chr10_-_31288398 0.10 ENST00000538351.2
zinc finger protein 438
chr10_-_65028817 0.10 ENST00000542921.1
jumonji domain containing 1C
chr11_+_102980251 0.10 ENST00000334267.7
ENST00000398093.3
dynein, cytoplasmic 2, heavy chain 1
chr1_+_155107820 0.10 ENST00000484157.1
solute carrier family 50 (sugar efflux transporter), member 1
chr6_-_33168391 0.10 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
retinoid X receptor, beta
chrX_+_142967173 0.10 ENST00000370494.1
ubiquitin-conjugating enzyme E2N-like
chr4_-_16900242 0.10 ENST00000502640.1
ENST00000506732.1
LIM domain binding 2
chr1_+_162039558 0.10 ENST00000530878.1
ENST00000361897.5
nitric oxide synthase 1 (neuronal) adaptor protein
chr4_-_16900410 0.10 ENST00000304523.5
LIM domain binding 2
chr2_+_171571827 0.10 ENST00000375281.3
Sp5 transcription factor

Network of associatons between targets according to the STRING database.

First level regulatory network of DBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.3 0.8 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.2 0.7 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 1.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.2 1.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 0.5 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.4 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.4 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.3 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.1 0.3 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.7 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 1.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 2.1 GO:0072189 ureter development(GO:0072189)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.2 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.4 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.7 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.1 GO:1903762 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.2 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.0 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.1 GO:2000173 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.1 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.0 0.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.2 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.0 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.4 GO:0051016 barbed-end actin filament capping(GO:0051016)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 1.8 GO:0097440 apical dendrite(GO:0097440)
0.1 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0033010 paranodal junction(GO:0033010)
0.0 0.6 GO:0071565 nBAF complex(GO:0071565)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0016160 amylase activity(GO:0016160)
0.1 0.3 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.1 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 1.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.8 GO:0045545 syndecan binding(GO:0045545)
0.1 0.2 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 1.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 1.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.7 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 2.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.7 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation