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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for DRGX_PROP1

Z-value: 0.88

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Transcription factors associated with DRGX_PROP1

Gene Symbol Gene ID Gene Info
DRGX
ENSG00000165606.4 dorsal root ganglia homeobox
PROP1
ENSG00000175325.2 PROP paired-like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PROP1hg19_v2_chr5_-_177423243_177423243-0.596.4e-04Click!

Activity profile of DRGX_PROP1 motif

Sorted Z-values of DRGX_PROP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_31823792 13.34 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPIFA1
BPI fold containing family A, member 1
chr13_+_50589390 6.20 ENST00000360473.4
ENST00000312942.1
KCNRG
potassium channel regulator
chr4_-_100356291 5.18 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr4_-_100356551 5.18 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr9_-_34397800 4.70 ENST00000297623.2
C9orf24
chromosome 9 open reading frame 24
chrX_+_35937843 3.91 ENST00000297866.5
CXorf22
chromosome X open reading frame 22
chr14_+_75536280 3.66 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr6_+_88117683 3.35 ENST00000369562.4
C6ORF165
UPF0704 protein C6orf165
chr5_-_160279207 3.10 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr7_+_90338712 2.99 ENST00000265741.3
ENST00000406263.1
CDK14
cyclin-dependent kinase 14
chr5_-_54468974 2.96 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B
cell division cycle 20B
chr5_-_137475071 2.94 ENST00000265191.2
NME5
NME/NM23 family member 5
chr8_-_10512569 2.82 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr1_-_92371839 2.73 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr6_-_76072719 2.60 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr14_+_62584197 2.40 ENST00000334389.4
LINC00643
long intergenic non-protein coding RNA 643
chr11_-_40315640 2.20 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr8_-_26724784 2.18 ENST00000380573.3
ADRA1A
adrenoceptor alpha 1A
chr18_-_52989525 2.13 ENST00000457482.3
TCF4
transcription factor 4
chr2_+_191334212 2.12 ENST00000444317.1
ENST00000535751.1
MFSD6
major facilitator superfamily domain containing 6
chr3_-_3151664 1.96 ENST00000256452.3
ENST00000311981.8
ENST00000430514.2
ENST00000456302.1
IL5RA
interleukin 5 receptor, alpha
chr6_-_32908792 1.91 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr5_+_142149955 1.91 ENST00000378004.3
ARHGAP26
Rho GTPase activating protein 26
chr10_-_61900762 1.90 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr7_+_123241908 1.88 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15
ankyrin repeat and SOCS box containing 15
chr5_+_140571902 1.87 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr2_+_179184955 1.75 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr17_+_68071389 1.73 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr8_+_67039131 1.72 ENST00000315962.4
ENST00000353317.5
TRIM55
tripartite motif containing 55
chr17_+_68071458 1.70 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr5_-_111312622 1.67 ENST00000395634.3
NREP
neuronal regeneration related protein
chr5_+_68860949 1.60 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chrX_+_77166172 1.57 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr2_+_162272605 1.54 ENST00000389554.3
TBR1
T-box, brain, 1
chr6_+_116691001 1.48 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr18_-_52989217 1.46 ENST00000570287.2
TCF4
transcription factor 4
chr11_-_26593779 1.43 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr14_-_75536182 1.41 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr11_-_96076334 1.40 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr3_+_138340049 1.40 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr10_+_53806501 1.34 ENST00000373975.2
PRKG1
protein kinase, cGMP-dependent, type I
chr17_+_71228740 1.33 ENST00000268942.8
ENST00000359042.2
C17orf80
chromosome 17 open reading frame 80
chr1_+_50459990 1.33 ENST00000448346.1
AL645730.2
AL645730.2
chrX_+_36254051 1.30 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr3_+_111393659 1.28 ENST00000477665.1
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr6_-_111804905 1.23 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr3_+_138340067 1.19 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr15_+_66874502 1.13 ENST00000558797.1
RP11-321F6.1
HCG2003567; Uncharacterized protein
chr22_+_25615489 1.11 ENST00000398215.2
CRYBB2
crystallin, beta B2
chr1_+_244214577 1.09 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr17_+_53342311 1.06 ENST00000226067.5
HLF
hepatic leukemia factor
chr11_-_26593649 1.05 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr6_+_88106840 1.05 ENST00000369570.4
C6orf164
chromosome 6 open reading frame 164
chr10_+_695888 1.03 ENST00000441152.2
PRR26
proline rich 26
chr11_-_26588634 1.02 ENST00000436318.2
ENST00000281268.8
MUC15
mucin 15, cell surface associated
chr12_-_10151773 1.00 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr12_+_75784850 0.99 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr2_-_145278475 0.96 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr11_-_26593677 0.96 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr4_+_48485341 0.95 ENST00000273861.4
SLC10A4
solute carrier family 10, member 4
chr15_+_44092784 0.94 ENST00000458412.1
HYPK
huntingtin interacting protein K
chr7_-_25268104 0.93 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr6_-_134639180 0.93 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr17_+_3118915 0.92 ENST00000304094.1
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr3_-_27763803 0.92 ENST00000449599.1
EOMES
eomesodermin
chr2_+_149895207 0.91 ENST00000409876.1
LYPD6B
LY6/PLAUR domain containing 6B
chr5_-_111093759 0.89 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr5_-_61031495 0.88 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
CTD-2170G1.2
chr11_-_57479673 0.88 ENST00000337672.2
ENST00000431606.2
MED19
mediator complex subunit 19
chr16_+_68119247 0.85 ENST00000575270.1
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr2_+_149894968 0.84 ENST00000409642.3
LYPD6B
LY6/PLAUR domain containing 6B
chr16_+_68119324 0.84 ENST00000349223.5
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr5_+_98109322 0.82 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chrX_-_15332665 0.78 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr12_-_52946923 0.77 ENST00000267119.5
KRT71
keratin 71
chr3_-_12587055 0.75 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr3_-_186262166 0.71 ENST00000307944.5
CRYGS
crystallin, gamma S
chr1_-_169703203 0.71 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
SELE
selectin E
chr11_+_57480046 0.70 ENST00000378312.4
ENST00000278422.4
TMX2
thioredoxin-related transmembrane protein 2
chrY_-_6742068 0.69 ENST00000215479.5
AMELY
amelogenin, Y-linked
chr12_-_75784669 0.67 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
CAPS2
calcyphosine 2
chr5_+_140079919 0.65 ENST00000274712.3
ZMAT2
zinc finger, matrin-type 2
chr20_-_34330129 0.65 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RBM39
RNA binding motif protein 39
chr21_-_15583165 0.65 ENST00000536861.1
LIPI
lipase, member I
chr15_+_57511609 0.65 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
TCF12
transcription factor 12
chr4_-_23735183 0.65 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr16_+_68119440 0.64 ENST00000346183.3
ENST00000329524.4
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr1_+_12976450 0.63 ENST00000361079.2
PRAMEF7
PRAME family member 7
chr10_-_102989551 0.61 ENST00000370193.2
LBX1
ladybird homeobox 1
chr6_-_24358264 0.58 ENST00000378454.3
DCDC2
doublecortin domain containing 2
chr3_+_149191723 0.57 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr7_+_152456829 0.57 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr7_+_152456904 0.57 ENST00000537264.1
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr3_-_191000172 0.56 ENST00000427544.2
UTS2B
urotensin 2B
chr5_+_140207536 0.55 ENST00000529310.1
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chr11_-_124190184 0.54 ENST00000357438.2
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr16_+_53133070 0.54 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr5_+_142149932 0.54 ENST00000274498.4
ARHGAP26
Rho GTPase activating protein 26
chr3_-_11623804 0.54 ENST00000451674.2
VGLL4
vestigial like 4 (Drosophila)
chr5_+_61874562 0.53 ENST00000334994.5
ENST00000409534.1
LRRC70
IPO11
leucine rich repeat containing 70
importin 11
chr15_-_52970820 0.53 ENST00000261844.7
ENST00000399202.4
ENST00000562135.1
FAM214A
family with sequence similarity 214, member A
chr17_-_29641084 0.52 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr6_-_137314371 0.51 ENST00000432330.1
ENST00000418699.1
RP11-55K22.5
RP11-55K22.5
chr4_-_87028478 0.49 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr1_-_151148492 0.48 ENST00000295314.4
TMOD4
tropomodulin 4 (muscle)
chr3_-_27764190 0.48 ENST00000537516.1
EOMES
eomesodermin
chr1_+_174933899 0.47 ENST00000367688.3
RABGAP1L
RAB GTPase activating protein 1-like
chr17_+_44588877 0.46 ENST00000576629.1
LRRC37A2
leucine rich repeat containing 37, member A2
chr14_-_38064198 0.46 ENST00000250448.2
FOXA1
forkhead box A1
chr11_+_55029628 0.45 ENST00000417545.2
TRIM48
tripartite motif containing 48
chr1_-_232651312 0.44 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr9_+_2159850 0.44 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_32390925 0.44 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
SLC30A6
solute carrier family 30 (zinc transporter), member 6
chr11_+_5372738 0.44 ENST00000380219.1
OR51B6
olfactory receptor, family 51, subfamily B, member 6
chr3_+_155860751 0.42 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr16_-_74700737 0.40 ENST00000576652.1
ENST00000572337.1
ENST00000571750.1
ENST00000572990.1
ENST00000361070.4
RFWD3
ring finger and WD repeat domain 3
chr5_-_111091948 0.40 ENST00000447165.2
NREP
neuronal regeneration related protein
chr8_+_39792474 0.39 ENST00000502986.2
IDO2
indoleamine 2,3-dioxygenase 2
chr15_+_44719970 0.37 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr17_+_71228537 0.37 ENST00000577615.1
ENST00000585109.1
C17orf80
chromosome 17 open reading frame 80
chr9_-_39239171 0.36 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr1_-_151148442 0.36 ENST00000441701.1
ENST00000416280.2
TMOD4
tropomodulin 4 (muscle)
chr3_-_157824292 0.36 ENST00000483851.2
SHOX2
short stature homeobox 2
chr19_-_11456905 0.35 ENST00000588560.1
ENST00000592952.1
TMEM205
transmembrane protein 205
chr5_-_59783882 0.35 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr13_+_53602894 0.35 ENST00000219022.2
OLFM4
olfactomedin 4
chr19_-_11456722 0.35 ENST00000354882.5
TMEM205
transmembrane protein 205
chr2_+_109237717 0.34 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chrX_+_108779004 0.34 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr2_-_58468437 0.33 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
FANCL
Fanconi anemia, complementation group L
chr3_+_2933893 0.32 ENST00000397459.2
CNTN4
contactin 4
chr20_+_32150140 0.32 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr19_-_11456872 0.31 ENST00000586218.1
TMEM205
transmembrane protein 205
chrX_+_68835911 0.30 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA
ectodysplasin A
chr4_+_113568207 0.29 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr6_+_3259122 0.29 ENST00000438998.2
ENST00000380305.4
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr5_+_140514782 0.29 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr13_-_47471155 0.29 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr5_-_160973649 0.28 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr2_+_74685413 0.28 ENST00000233615.2
WBP1
WW domain binding protein 1
chr12_+_54422142 0.28 ENST00000243108.4
HOXC6
homeobox C6
chr2_+_128458514 0.27 ENST00000310981.4
SFT2D3
SFT2 domain containing 3
chr7_-_7575477 0.26 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr3_-_165555200 0.25 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr9_+_21440440 0.25 ENST00000276927.1
IFNA1
interferon, alpha 1
chr1_+_42846443 0.24 ENST00000410070.2
ENST00000431473.3
RIMKLA
ribosomal modification protein rimK-like family member A
chr9_-_27005686 0.24 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chr3_-_195310802 0.24 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr3_-_45837959 0.24 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr3_+_153839149 0.24 ENST00000465093.1
ENST00000465817.1
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr4_+_160188889 0.24 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr1_-_241799232 0.24 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr8_+_77318769 0.23 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr6_+_12007963 0.23 ENST00000607445.1
RP11-456H18.2
RP11-456H18.2
chr6_+_12007897 0.22 ENST00000437559.1
RP11-456H18.2
RP11-456H18.2
chr16_+_24549014 0.22 ENST00000564314.1
ENST00000567686.1
RBBP6
retinoblastoma binding protein 6
chr17_-_27332931 0.22 ENST00000442608.3
ENST00000335960.6
SEZ6
seizure related 6 homolog (mouse)
chr21_+_17442799 0.21 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr3_-_197300194 0.21 ENST00000358186.2
ENST00000431056.1
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr9_+_42671887 0.20 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chr9_+_12693336 0.20 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr11_+_49050504 0.20 ENST00000332682.7
TRIM49B
tripartite motif containing 49B
chr3_-_9291063 0.19 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr9_-_70465758 0.19 ENST00000489273.1
CBWD5
COBW domain containing 5
chrX_+_11311533 0.19 ENST00000380714.3
ENST00000380712.3
ENST00000348912.4
AMELX
amelogenin, X-linked
chr1_-_21377383 0.18 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr1_+_151227179 0.18 ENST00000368884.3
ENST00000368881.4
PSMD4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
chr12_-_57873631 0.17 ENST00000393791.3
ENST00000356411.2
ENST00000552249.1
ARHGAP9
Rho GTPase activating protein 9
chr16_+_1728257 0.17 ENST00000248098.3
ENST00000562684.1
ENST00000561516.1
ENST00000382711.5
ENST00000566742.1
HN1L
hematological and neurological expressed 1-like
chr1_+_158323755 0.17 ENST00000368157.1
ENST00000368156.1
ENST00000368155.3
ENST00000368154.1
ENST00000368160.3
ENST00000368161.3
CD1E
CD1e molecule
chr11_-_111649015 0.17 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr8_-_57123815 0.16 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr13_-_95131923 0.16 ENST00000377028.5
ENST00000446125.1
DCT
dopachrome tautomerase
chr11_+_127140956 0.16 ENST00000608214.1
RP11-480C22.1
RP11-480C22.1
chr8_-_20040638 0.16 ENST00000519026.1
ENST00000276373.5
ENST00000440926.1
ENST00000437980.1
SLC18A1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr17_-_39623681 0.16 ENST00000225899.3
KRT32
keratin 32
chr2_+_36923830 0.15 ENST00000379242.3
ENST00000389975.3
VIT
vitrin
chr12_+_19358228 0.15 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr5_+_133562095 0.15 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr2_+_179317994 0.15 ENST00000375129.4
DFNB59
deafness, autosomal recessive 59
chr3_-_45838011 0.15 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr9_+_44867571 0.13 ENST00000377548.2
RP11-160N1.10
RP11-160N1.10
chr16_-_21663919 0.13 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr12_-_57873329 0.13 ENST00000424809.2
ARHGAP9
Rho GTPase activating protein 9
chr5_+_59783941 0.13 ENST00000506884.1
ENST00000504876.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr17_+_39240459 0.13 ENST00000391417.4
KRTAP4-7
keratin associated protein 4-7
chr12_-_118796910 0.13 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr11_-_58499434 0.12 ENST00000344743.3
ENST00000278400.3
GLYAT
glycine-N-acyltransferase
chr19_+_54619125 0.12 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
PRPF31
pre-mRNA processing factor 31
chr3_-_18480260 0.12 ENST00000454909.2
SATB1
SATB homeobox 1
chr14_-_21567009 0.12 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219
zinc finger protein 219
chrX_+_100878079 0.12 ENST00000471229.2
ARMCX3
armadillo repeat containing, X-linked 3
chr8_-_20040601 0.11 ENST00000265808.7
ENST00000522513.1
SLC18A1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr1_-_186430222 0.10 ENST00000391997.2
PDC
phosducin
chr11_+_85359062 0.10 ENST00000532180.1
TMEM126A
transmembrane protein 126A
chr3_+_111697843 0.10 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
ABHD10
abhydrolase domain containing 10
chr6_-_32908765 0.10 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr6_-_41039567 0.09 ENST00000468811.1
OARD1
O-acyl-ADP-ribose deacylase 1
chr17_-_29641104 0.09 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr16_-_69373396 0.08 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8

Network of associatons between targets according to the STRING database.

First level regulatory network of DRGX_PROP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.4 GO:0010430 fatty acid omega-oxidation(GO:0010430)
3.3 13.3 GO:0044407 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.7 2.2 GO:0003099 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.7 2.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.7 2.0 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.7 2.0 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.5 1.6 GO:0071284 cellular response to lead ion(GO:0071284)
0.5 8.5 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.5 1.4 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.3 1.5 GO:0021764 amygdala development(GO:0021764)
0.2 2.9 GO:0006228 UTP biosynthetic process(GO:0006228)
0.2 1.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.5 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.9 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 3.1 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.9 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 2.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 0.9 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.1 0.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.2 GO:2000670 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.3 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 1.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 3.4 GO:0010107 potassium ion import(GO:0010107)
0.1 2.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 2.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 0.6 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.3 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 1.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 3.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0048021 regulation of melanin biosynthetic process(GO:0048021) regulation of secondary metabolite biosynthetic process(GO:1900376)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.4 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.4 GO:0015824 proline transport(GO:0015824)
0.0 2.4 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.9 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.8 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.0 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.7 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 1.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 1.8 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 3.0 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.2 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 1.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.0 0.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.6 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0051028 mRNA transport(GO:0051028)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 1.1 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.6 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 1.6 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.6 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 2.6 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.3 GO:0036297 interstrand cross-link repair(GO:0036297)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.6 3.0 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 1.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.6 GO:0000439 core TFIIH complex(GO:0000439)
0.1 2.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.9 GO:0043194 axon initial segment(GO:0043194)
0.1 1.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 2.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.6 GO:0060091 kinocilium(GO:0060091)
0.0 0.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 3.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 3.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.9 GO:0005901 caveola(GO:0005901)
0.0 0.8 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 2.2 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 2.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.6 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.4 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.7 2.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.7 2.0 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.5 1.6 GO:0032767 copper-dependent protein binding(GO:0032767)
0.4 3.0 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.3 1.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 3.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 1.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 2.7 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 1.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 3.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 1.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.4 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 1.8 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 3.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.9 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 1.4 GO:0003712 transcription cofactor activity(GO:0003712)
0.1 2.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.3 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 2.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.3 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 3.0 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.7 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 1.8 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 1.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.3 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.4 GO:0070402 NADPH binding(GO:0070402)
0.0 0.2 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 1.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 11.6 GO:0008289 lipid binding(GO:0008289)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 1.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 2.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 2.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 3.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 4.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID INSULIN PATHWAY Insulin Pathway
0.0 0.8 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 10.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 4.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 4.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 4.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 2.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.4 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 2.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway