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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for DUXA

Z-value: 1.04

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Transcription factors associated with DUXA

Gene Symbol Gene ID Gene Info
DUXA
ENSG00000258873.2 double homeobox A

Activity profile of DUXA motif

Sorted Z-values of DUXA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_51471362 9.88 ENST00000376853.4
ENST00000424910.2
KLK6
kallikrein-related peptidase 6
chr19_-_51471381 9.77 ENST00000594641.1
KLK6
kallikrein-related peptidase 6
chr19_-_51472031 7.30 ENST00000391808.1
KLK6
kallikrein-related peptidase 6
chr4_+_69313145 5.70 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr1_-_153113927 4.93 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr8_+_7397150 4.73 ENST00000533250.1
RP11-1118M6.1
proline rich 23 domain containing 1
chr1_+_152975488 4.72 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr8_-_7638935 4.70 ENST00000528972.1
AC084121.16
proline rich 23 domain containing 2
chr18_+_61445007 4.08 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr2_+_228678550 3.97 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr1_+_17575584 3.38 ENST00000375460.3
PADI3
peptidyl arginine deiminase, type III
chr11_-_89653576 3.24 ENST00000420869.1
TRIM49D1
tripartite motif containing 49D1
chr17_-_39553844 2.81 ENST00000251645.2
KRT31
keratin 31
chr6_-_150346607 2.80 ENST00000367341.1
ENST00000286380.2
RAET1L
retinoic acid early transcript 1L
chr2_+_234600253 2.63 ENST00000373424.1
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr8_-_91095099 2.52 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr8_-_125577940 2.45 ENST00000519168.1
ENST00000395508.2
MTSS1
metastasis suppressor 1
chr15_-_80263506 2.43 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr21_+_30502806 2.39 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr7_-_93520259 2.21 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr7_-_93520191 1.99 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr19_-_6393216 1.96 ENST00000595047.1
GTF2F1
general transcription factor IIF, polypeptide 1, 74kDa
chr20_+_23471727 1.95 ENST00000449810.1
ENST00000246012.1
CST8
cystatin 8 (cystatin-related epididymal specific)
chr1_-_110933611 1.93 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr1_-_110933663 1.93 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr19_+_7030589 1.92 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3-like 5
chr19_-_7040190 1.91 ENST00000381394.4
MBD3L4
methyl-CpG binding domain protein 3-like 4
chr2_-_208994548 1.83 ENST00000282141.3
CRYGC
crystallin, gamma C
chr19_-_6393465 1.82 ENST00000394456.5
GTF2F1
general transcription factor IIF, polypeptide 1, 74kDa
chr3_-_149093499 1.79 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr19_+_7049332 1.77 ENST00000381393.3
MBD3L2
methyl-CpG binding domain protein 3-like 2
chr4_+_148653206 1.68 ENST00000336498.3
ARHGAP10
Rho GTPase activating protein 10
chr14_+_20937538 1.65 ENST00000361505.5
ENST00000553591.1
PNP
purine nucleoside phosphorylase
chr14_+_22615942 1.61 ENST00000390457.2
TRAV27
T cell receptor alpha variable 27
chr7_-_99277610 1.60 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 5
chr10_+_11865347 1.57 ENST00000277570.5
PROSER2
proline and serine-rich protein 2
chr5_+_150404904 1.53 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr6_+_53883790 1.51 ENST00000509997.1
MLIP
muscular LMNA-interacting protein
chr19_-_7058651 1.50 ENST00000333843.4
MBD3L3
methyl-CpG binding domain protein 3-like 3
chr2_-_40680578 1.46 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr13_+_109248500 1.41 ENST00000356711.2
MYO16
myosin XVI
chr15_+_80733570 1.39 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr7_+_141490017 1.38 ENST00000247883.4
TAS2R5
taste receptor, type 2, member 5
chr6_-_111888474 1.34 ENST00000368735.1
TRAF3IP2
TRAF3 interacting protein 2
chr6_-_66417107 1.28 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS
eyes shut homolog (Drosophila)
chr6_+_31126291 1.27 ENST00000376257.3
ENST00000376255.4
TCF19
transcription factor 19
chr11_+_28129795 1.26 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15
methyltransferase like 15
chr12_+_122688090 1.25 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr6_-_74104856 1.25 ENST00000441145.1
OOEP
oocyte expressed protein
chr5_-_150948414 1.23 ENST00000261800.5
FAT2
FAT atypical cadherin 2
chrX_+_85969626 1.15 ENST00000484479.1
DACH2
dachshund homolog 2 (Drosophila)
chr3_-_47950745 1.14 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr16_-_15149917 1.13 ENST00000287706.3
NTAN1
N-terminal asparagine amidase
chr3_+_190333097 1.13 ENST00000412080.1
IL1RAP
interleukin 1 receptor accessory protein
chr1_-_231560790 1.12 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr11_-_2924970 1.12 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr6_+_53883708 1.12 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
MLIP
muscular LMNA-interacting protein
chr5_-_16742330 1.08 ENST00000505695.1
ENST00000427430.2
MYO10
myosin X
chr5_+_154237778 1.07 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
CNOT8
CCR4-NOT transcription complex, subunit 8
chr6_+_35996859 1.07 ENST00000472333.1
MAPK14
mitogen-activated protein kinase 14
chr1_-_12908578 1.04 ENST00000317869.6
HNRNPCL1
heterogeneous nuclear ribonucleoprotein C-like 1
chr1_+_12916941 1.03 ENST00000240189.2
PRAMEF2
PRAME family member 2
chr6_+_42584847 1.02 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr9_+_34652164 1.02 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr1_+_153003671 1.00 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr11_+_13690249 0.99 ENST00000532701.1
FAR1
fatty acyl CoA reductase 1
chr13_+_57721622 0.98 ENST00000377930.1
PRR20B
proline rich 20B
chr10_-_29923893 0.97 ENST00000355867.4
SVIL
supervillin
chr18_+_61554932 0.95 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr10_+_78078088 0.95 ENST00000496424.2
C10orf11
chromosome 10 open reading frame 11
chr1_-_12946025 0.95 ENST00000235349.5
PRAMEF4
PRAME family member 4
chr8_+_70378852 0.94 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1
sulfatase 1
chr11_+_114270752 0.93 ENST00000540163.1
RBM7
RNA binding motif protein 7
chr16_-_21222868 0.92 ENST00000574091.1
ENST00000219593.4
ZP2
zona pellucida glycoprotein 2 (sperm receptor)
chr6_+_26199737 0.91 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr2_-_166930131 0.90 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr1_-_13005246 0.90 ENST00000415464.2
PRAMEF6
PRAME family member 6
chr11_-_89654935 0.89 ENST00000530311.2
TRIM49D1
tripartite motif containing 49D1
chr2_-_69098566 0.89 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr6_+_31939608 0.88 ENST00000375331.2
ENST00000375333.2
STK19
serine/threonine kinase 19
chr10_-_29811456 0.88 ENST00000535393.1
SVIL
supervillin
chr1_+_74701062 0.87 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr15_+_66679155 0.87 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr4_-_89951028 0.87 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr16_+_30006997 0.85 ENST00000304516.7
INO80E
INO80 complex subunit E
chr12_-_102874330 0.83 ENST00000307046.8
IGF1
insulin-like growth factor 1 (somatomedin C)
chr11_+_68671310 0.83 ENST00000255078.3
ENST00000539224.1
IGHMBP2
immunoglobulin mu binding protein 2
chr12_-_102874102 0.82 ENST00000392905.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chrX_+_18725758 0.80 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr5_+_149877334 0.79 ENST00000523767.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr4_+_88529681 0.79 ENST00000399271.1
DSPP
dentin sialophosphoprotein
chr16_+_30007524 0.78 ENST00000567254.1
ENST00000567705.1
INO80E
INO80 complex subunit E
chr12_-_49259643 0.78 ENST00000309739.5
RND1
Rho family GTPase 1
chr15_-_91565770 0.78 ENST00000535906.1
ENST00000333371.3
VPS33B
vacuolar protein sorting 33 homolog B (yeast)
chr1_-_153283194 0.77 ENST00000290722.1
PGLYRP3
peptidoglycan recognition protein 3
chr3_+_159943362 0.77 ENST00000326474.3
C3orf80
chromosome 3 open reading frame 80
chr3_-_195997410 0.76 ENST00000419333.1
PCYT1A
phosphate cytidylyltransferase 1, choline, alpha
chr9_-_27005686 0.76 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chrX_-_74376108 0.76 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr11_-_13517565 0.76 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr2_+_201994208 0.75 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr4_-_14889791 0.74 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
LINC00504
long intergenic non-protein coding RNA 504
chr6_+_26251835 0.74 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr2_+_161993465 0.74 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr10_+_18689637 0.73 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr12_-_11062161 0.72 ENST00000390677.2
TAS2R13
taste receptor, type 2, member 13
chr3_+_45927994 0.72 ENST00000357632.2
ENST00000395963.2
CCR9
chemokine (C-C motif) receptor 9
chr17_-_10276319 0.72 ENST00000252172.4
ENST00000418404.3
MYH13
myosin, heavy chain 13, skeletal muscle
chr4_-_57844989 0.71 ENST00000264230.4
NOA1
nitric oxide associated 1
chr1_-_117210290 0.71 ENST00000369483.1
ENST00000369486.3
IGSF3
immunoglobulin superfamily, member 3
chr6_-_49604545 0.71 ENST00000371175.4
ENST00000229810.7
RHAG
Rh-associated glycoprotein
chr3_-_128186091 0.70 ENST00000319153.3
DNAJB8
DnaJ (Hsp40) homolog, subfamily B, member 8
chr5_-_119740532 0.70 ENST00000569928.1
RP11-574H6.1
RP11-574H6.1
chr11_-_89540388 0.69 ENST00000532501.2
TRIM49
tripartite motif containing 49
chr1_+_12834984 0.68 ENST00000357726.4
PRAMEF12
PRAME family member 12
chr2_+_161993412 0.67 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr8_-_49833978 0.66 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr1_+_13421176 0.66 ENST00000376152.1
PRAMEF9
PRAME family member 9
chr4_-_119759795 0.66 ENST00000419654.2
SEC24D
SEC24 family member D
chr16_+_6533729 0.66 ENST00000551752.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_-_11374904 0.65 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr19_-_47349395 0.65 ENST00000597020.1
AP2S1
adaptor-related protein complex 2, sigma 1 subunit
chr13_+_98605902 0.64 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
IPO5
importin 5
chr7_+_135611542 0.64 ENST00000416501.1
AC015987.2
AC015987.2
chr19_-_14785622 0.63 ENST00000443157.2
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr1_+_13359819 0.62 ENST00000376168.1
PRAMEF5
PRAME family member 5
chr19_-_14785698 0.62 ENST00000344373.4
ENST00000595472.1
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr10_-_112064665 0.62 ENST00000369603.5
SMNDC1
survival motor neuron domain containing 1
chr12_-_54653313 0.62 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr16_-_89785777 0.61 ENST00000561976.1
VPS9D1
VPS9 domain containing 1
chr7_+_93535817 0.61 ENST00000248572.5
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr16_+_57220193 0.61 ENST00000564435.1
ENST00000562959.1
ENST00000394420.4
ENST00000568505.2
ENST00000537866.1
RSPRY1
ring finger and SPRY domain containing 1
chr6_+_168418553 0.60 ENST00000354419.2
ENST00000351261.3
KIF25
kinesin family member 25
chr8_+_86747543 0.60 ENST00000425429.2
REXO1L11P
REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 11, pseudogene
chr1_+_50569575 0.60 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr9_-_13279563 0.60 ENST00000541718.1
MPDZ
multiple PDZ domain protein
chr15_+_39542867 0.60 ENST00000318578.3
ENST00000561223.1
C15orf54
chromosome 15 open reading frame 54
chr12_+_8662057 0.59 ENST00000382064.2
CLEC4D
C-type lectin domain family 4, member D
chr13_+_57715052 0.59 ENST00000377931.1
PRR20A
proline rich 20A
chr11_+_62496114 0.58 ENST00000532583.1
TTC9C
tetratricopeptide repeat domain 9C
chr19_-_14785674 0.58 ENST00000253673.5
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr8_-_49834299 0.57 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr11_+_95523621 0.57 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
CEP57
centrosomal protein 57kDa
chr1_+_95616933 0.57 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr4_+_169552748 0.56 ENST00000504519.1
ENST00000512127.1
PALLD
palladin, cytoskeletal associated protein
chr11_+_30253410 0.55 ENST00000533718.1
FSHB
follicle stimulating hormone, beta polypeptide
chr8_+_82192501 0.55 ENST00000297258.6
FABP5
fatty acid binding protein 5 (psoriasis-associated)
chr16_+_6533380 0.55 ENST00000552089.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr13_+_57728195 0.55 ENST00000544357.2
PRR20C
proline rich 20C
chr13_+_57734766 0.55 ENST00000452123.3
PRR20D
proline rich 20D
chr13_+_57741331 0.55 ENST00000434815.1
PRR20E
proline rich 20E
chr6_-_138820624 0.54 ENST00000343505.5
NHSL1
NHS-like 1
chr11_+_4116054 0.54 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr2_-_201753980 0.54 ENST00000443398.1
ENST00000286175.8
ENST00000409449.1
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr10_-_46620012 0.54 ENST00000508602.1
ENST00000374339.3
ENST00000502254.1
ENST00000437863.1
ENST00000374342.2
ENST00000395722.3
PTPN20A
protein tyrosine phosphatase, non-receptor type 20A
chr19_-_54663473 0.54 ENST00000222224.3
LENG1
leukocyte receptor cluster (LRC) member 1
chr8_-_16859690 0.53 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr19_+_56187987 0.53 ENST00000411543.2
EPN1
epsin 1
chr1_-_13115578 0.52 ENST00000414205.2
PRAMEF6
PRAME family member 6
chr5_-_180665195 0.52 ENST00000509148.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chrX_+_37865804 0.52 ENST00000297875.2
ENST00000357972.5
SYTL5
synaptotagmin-like 5
chr8_-_7343922 0.52 ENST00000335479.2
DEFB106B
defensin, beta 106B
chr6_+_130339710 0.52 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr3_-_113918254 0.52 ENST00000460779.1
DRD3
dopamine receptor D3
chr12_-_118797475 0.51 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr6_-_133055896 0.51 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr5_-_77590480 0.51 ENST00000519295.1
ENST00000255194.6
AP3B1
adaptor-related protein complex 3, beta 1 subunit
chr12_+_12878829 0.51 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr2_+_201994569 0.51 ENST00000457277.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr2_-_198062758 0.50 ENST00000328737.2
ANKRD44
ankyrin repeat domain 44
chr6_-_74104816 0.50 ENST00000370363.1
OOEP
oocyte expressed protein
chr4_+_56719782 0.49 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
EXOC1
exocyst complex component 1
chr1_-_234667504 0.49 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr5_-_150537279 0.48 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
ANXA6
annexin A6
chr5_-_9712312 0.48 ENST00000506620.1
ENST00000514078.1
ENST00000606744.1
TAS2R1
CTD-2143L24.1
taste receptor, type 2, member 1
CTD-2143L24.1
chrX_+_46306624 0.48 ENST00000360017.5
KRBOX4
KRAB box domain containing 4
chr2_+_11674213 0.48 ENST00000381486.2
GREB1
growth regulation by estrogen in breast cancer 1
chr7_+_1126461 0.48 ENST00000297469.3
GPER1
G protein-coupled estrogen receptor 1
chr10_-_48806939 0.48 ENST00000374233.3
ENST00000507417.1
ENST00000512321.1
ENST00000395660.2
ENST00000374235.2
ENST00000395661.3
PTPN20B
protein tyrosine phosphatase, non-receptor type 20B
chr2_-_175629164 0.47 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr2_-_201753859 0.47 ENST00000409361.1
ENST00000392283.4
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr4_+_147096837 0.47 ENST00000296581.5
ENST00000502781.1
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_+_80748619 0.47 ENST00000504263.1
PCAT4
prostate cancer associated transcript 4 (non-protein coding)
chr13_-_45775162 0.46 ENST00000405872.1
KCTD4
potassium channel tetramerization domain containing 4
chr5_-_78809950 0.46 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr14_-_106322288 0.46 ENST00000390559.2
IGHM
immunoglobulin heavy constant mu
chr12_-_118628350 0.46 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr2_+_201994042 0.46 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr5_+_145826867 0.45 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr20_-_44298878 0.45 ENST00000324384.3
ENST00000356562.2
WFDC11
WAP four-disulfide core domain 11
chr9_+_124329336 0.45 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr7_+_93535866 0.45 ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr12_-_14967095 0.44 ENST00000316048.2
SMCO3
single-pass membrane protein with coiled-coil domains 3
chrX_+_37639264 0.44 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr12_-_48963829 0.44 ENST00000301046.2
ENST00000549817.1
LALBA
lactalbumin, alpha-
chrX_+_135614293 0.44 ENST00000370634.3
VGLL1
vestigial like 1 (Drosophila)
chr9_-_95298314 0.44 ENST00000344604.5
ENST00000375540.1
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr1_+_13641973 0.44 ENST00000330087.5
PRAMEF15
PRAME family member 15
chr2_+_48796120 0.43 ENST00000394754.1
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr2_-_201753717 0.43 ENST00000409264.2
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3

Network of associatons between targets according to the STRING database.

First level regulatory network of DUXA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.2 27.0 GO:0016540 protein autoprocessing(GO:0016540)
1.0 4.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.7 3.4 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.6 1.7 GO:0006738 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.4 1.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.4 2.5 GO:0030035 microspike assembly(GO:0030035)
0.4 1.9 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.3 1.3 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.3 1.2 GO:0009822 alkaloid catabolic process(GO:0009822)
0.3 7.1 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.3 2.5 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.3 1.3 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.3 0.8 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.3 0.8 GO:0051714 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.3 1.5 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.3 0.8 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2 0.7 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.2 1.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 0.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.9 GO:0007343 egg activation(GO:0007343)
0.2 2.9 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 1.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 1.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.2 1.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.2 1.1 GO:0051012 microtubule sliding(GO:0051012)
0.2 1.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 2.9 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.2 1.7 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 0.8 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2 1.3 GO:0070475 rRNA base methylation(GO:0070475)
0.2 0.5 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.4 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 1.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.9 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 10.6 GO:0018149 peptide cross-linking(GO:0018149)
0.1 4.2 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 0.8 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.5 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.9 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.4 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.4 GO:0043605 cellular amide catabolic process(GO:0043605)
0.1 0.3 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.5 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 1.2 GO:0015886 heme transport(GO:0015886)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.4 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.9 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 2.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.3 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.6 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.8 GO:0015014 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.7 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.8 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.2 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 2.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.5 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.1 0.7 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 0.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 0.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.4 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.7 GO:0032808 lacrimal gland development(GO:0032808)
0.1 1.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.2 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 1.9 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 2.2 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.8 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:0046219 serotonin biosynthetic process(GO:0042427) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.0 0.2 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.4 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.9 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 1.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 3.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 2.8 GO:0007566 embryo implantation(GO:0007566)
0.0 0.5 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 2.8 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 1.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.0 0.6 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:0051775 response to redox state(GO:0051775)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.6 GO:0046602 regulation of mitotic centrosome separation(GO:0046602) negative regulation of centrosome cycle(GO:0046606)
0.0 1.0 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.7 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 2.8 GO:0070268 cornification(GO:0070268)
0.0 1.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.4 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374) phosphatidylcholine catabolic process(GO:0034638)
0.0 1.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 1.0 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.4 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 3.7 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.3 GO:0002323 natural killer cell activation involved in immune response(GO:0002323)
0.0 0.2 GO:0050650 chondroitin sulfate metabolic process(GO:0030204) chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.0 0.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 1.1 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.3 1.9 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 1.8 GO:0036449 microtubule minus-end(GO:0036449)
0.2 10.7 GO:0001533 cornified envelope(GO:0001533)
0.2 1.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 0.5 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.4 GO:1990742 microvesicle(GO:1990742)
0.1 1.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 0.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 1.1 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 0.8 GO:0042587 glycogen granule(GO:0042587)
0.1 0.8 GO:0032797 SMN complex(GO:0032797)
0.1 1.1 GO:0032433 filopodium tip(GO:0032433)
0.1 0.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 0.5 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 1.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.1 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 2.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.6 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.6 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.7 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 29.6 GO:0030141 secretory granule(GO:0030141)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.7 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 4.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.4 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 3.2 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.7 3.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.6 1.7 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.5 2.5 GO:0005499 vitamin D binding(GO:0005499)
0.4 3.8 GO:0019211 phosphatase activator activity(GO:0019211)
0.3 1.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.3 1.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.3 0.8 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.2 0.7 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 1.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 2.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 1.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.2 1.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2 0.8 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 0.8 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.2 1.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.2 7.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 1.8 GO:0008430 selenium binding(GO:0008430)
0.2 1.1 GO:0070728 leucine binding(GO:0070728)
0.2 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 1.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 2.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 2.4 GO:0051400 BH domain binding(GO:0051400)
0.1 0.4 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.5 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 1.2 GO:0015232 heme transporter activity(GO:0015232)
0.1 33.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.8 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.3 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.1 1.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 1.1 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.9 GO:0032190 acrosin binding(GO:0032190)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 3.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.7 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 1.0 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.9 GO:0031013 troponin I binding(GO:0031013)
0.1 1.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 3.0 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 9.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.9 GO:0031433 telethonin binding(GO:0031433)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 1.0 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 1.2 GO:0070330 aromatase activity(GO:0070330)
0.1 1.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 2.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 3.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 1.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.5 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.9 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 1.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0015085 calcium-transporting ATPase activity(GO:0005388) calcium ion transmembrane transporter activity(GO:0015085)
0.0 0.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.5 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 2.8 GO:0051015 actin filament binding(GO:0051015)
0.0 10.1 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.2 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 27.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.7 PID IGF1 PATHWAY IGF1 pathway
0.0 2.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.1 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 6.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 3.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.6 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 4.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 0.9 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 1.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 2.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 1.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.0 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.8 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 1.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 2.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.7 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus