Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
Navigation
Downloads
Results for E2F3
Z-value: 1.36
Motif logo
Transcription factors associated with E2F3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| E2F3 | hg19_v2_chr6_+_20403997_20404034 | -0.24 | 1.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_+_67465016 Show fit | 6.55 |
ENST00000326152.5
|
hydroxysteroid (11-beta) dehydrogenase 2 |
|
| chr21_+_42688686 Show fit | 5.41 |
ENST00000398652.3
ENST00000398647.3 |
family with sequence similarity 3, member B |
|
| chr21_+_42688657 Show fit | 5.26 |
ENST00000357985.2
|
family with sequence similarity 3, member B |
|
| chr6_+_116937636 Show fit | 5.18 |
ENST00000368581.4
ENST00000229554.5 ENST00000368580.4 |
radial spoke head 4 homolog A (Chlamydomonas) |
|
| chr6_-_132272504 Show fit | 4.00 |
ENST00000367976.3
|
connective tissue growth factor |
|
| chr6_+_163148973 Show fit | 3.97 |
ENST00000366888.2
|
PARK2 co-regulated |
|
| chr16_+_80574854 Show fit | 3.84 |
ENST00000305904.6
ENST00000568035.1 |
dynein, light chain, roadblock-type 2 |
|
| chr1_-_109655377 Show fit | 3.83 |
ENST00000369948.3
|
chromosome 1 open reading frame 194 |
|
| chr15_-_68497657 Show fit | 3.81 |
ENST00000448060.2
ENST00000467889.1 |
calmodulin-like 4 |
|
| chr15_-_56757329 Show fit | 3.76 |
ENST00000260453.3
|
meiosis-specific nuclear structural 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of E2F3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 10.1 | GO:0042073 | intraciliary transport(GO:0042073) |
| 0.4 | 6.5 | GO:0003084 | positive regulation of systemic arterial blood pressure(GO:0003084) |
| 0.3 | 6.0 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.2 | 5.4 | GO:0003341 | cilium movement(GO:0003341) |
| 1.3 | 5.1 | GO:0046909 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
| 0.1 | 5.0 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.3 | 4.9 | GO:0071850 | mitotic cell cycle arrest(GO:0071850) |
| 0.3 | 4.7 | GO:0006108 | malate metabolic process(GO:0006108) |
| 1.5 | 4.6 | GO:0034059 | response to anoxia(GO:0034059) |
| 0.2 | 4.4 | GO:0021670 | lateral ventricle development(GO:0021670) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.9 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 1.7 | 8.6 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.7 | 6.7 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.3 | 6.6 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 5.4 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 1.7 | 5.2 | GO:0001534 | radial spoke(GO:0001534) |
| 0.2 | 5.2 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 5.1 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.4 | 4.9 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.1 | 4.0 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.7 | GO:0005125 | cytokine activity(GO:0005125) |
| 2.2 | 6.5 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.2 | 5.9 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.1 | 5.4 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.7 | 4.7 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 0.1 | 4.5 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.8 | 3.9 | GO:0004306 | ethanolamine-phosphate cytidylyltransferase activity(GO:0004306) |
| 0.1 | 3.9 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 3.8 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.1 | 3.8 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.8 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 5.5 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 5.0 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 4.5 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 4.4 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.1 | 4.1 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.1 | 3.9 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 3.9 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 2.2 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 2.0 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 16.0 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.2 | 5.6 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.1 | 4.9 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.3 | 3.7 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 3.6 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 3.4 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 3.3 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.3 | 3.1 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.1 | 2.8 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 2.6 | REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | Genes involved in Processive synthesis on the lagging strand |