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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for E2F4

Z-value: 0.97

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Transcription factors associated with E2F4

Gene Symbol Gene ID Gene Info
ENSG00000205250.4 E2F transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F4hg19_v2_chr16_+_67226019_67226127-0.135.0e-01Click!

Activity profile of E2F4 motif

Sorted Z-values of E2F4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrY_+_22737678 3.05 ENST00000382772.3
eukaryotic translation initiation factor 1A, Y-linked
chrY_+_22737604 2.55 ENST00000361365.2
eukaryotic translation initiation factor 1A, Y-linked
chr14_-_55658323 2.55 ENST00000554067.1
ENST00000247191.2
discs, large (Drosophila) homolog-associated protein 5
chr2_+_10262857 2.35 ENST00000304567.5
ribonucleotide reductase M2
chr17_-_76183111 2.24 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
thymidine kinase 1, soluble
chr1_+_91966656 2.15 ENST00000428239.1
ENST00000426137.1
cell division cycle 7
chr1_+_91966384 2.14 ENST00000430031.2
ENST00000234626.6
cell division cycle 7
chr19_-_48673580 1.93 ENST00000427526.2
ligase I, DNA, ATP-dependent
chr12_-_77459306 1.91 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F transcription factor 7
chr19_-_48673552 1.90 ENST00000536218.1
ENST00000596549.1
ligase I, DNA, ATP-dependent
chr15_+_91260552 1.87 ENST00000355112.3
ENST00000560509.1
Bloom syndrome, RecQ helicase-like
chr8_-_95907423 1.78 ENST00000396133.3
ENST00000308108.4
cyclin E2
chr5_+_892745 1.75 ENST00000166345.3
thyroid hormone receptor interactor 13
chr11_-_64851496 1.60 ENST00000404147.3
ENST00000275517.3
cell division cycle associated 5
chr5_-_127873659 1.49 ENST00000262464.4
fibrillin 2
chr6_+_126661253 1.43 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
centromere protein W
chr22_+_19467261 1.42 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
cell division cycle 45
chr7_-_21985489 1.42 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
cell division cycle associated 7-like
chr4_-_185655278 1.33 ENST00000281453.5
centromere protein U
chr1_-_197115818 1.30 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr10_-_70231639 1.28 ENST00000551118.2
ENST00000358410.3
ENST00000399180.2
ENST00000399179.2
DNA replication helicase/nuclease 2
chr19_-_14016877 1.28 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
chromosome 19 open reading frame 57
chr2_-_203736452 1.24 ENST00000419460.1
islet cell autoantigen 1,69kDa-like
chr11_-_123525289 1.22 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
sodium channel, voltage-gated, type III, beta subunit
chr14_-_50154921 1.21 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
polymerase (DNA directed), epsilon 2, accessory subunit
chr8_+_27491381 1.15 ENST00000337221.4
scavenger receptor class A, member 3
chr1_-_26185844 1.14 ENST00000538789.1
ENST00000374298.3
aurora kinase A and ninein interacting protein
chr9_-_35080013 1.13 ENST00000378643.3
Fanconi anemia, complementation group G
chr6_+_151561506 1.09 ENST00000253332.1
A kinase (PRKA) anchor protein 12
chr13_+_34392185 1.08 ENST00000380071.3
replication factor C (activator 1) 3, 38kDa
chr8_+_48873453 1.07 ENST00000523944.1
minichromosome maintenance complex component 4
chr8_+_48873479 1.05 ENST00000262105.2
minichromosome maintenance complex component 4
chr12_-_56843161 1.05 ENST00000554616.1
ENST00000553532.1
ENST00000229201.4
timeless circadian clock
chr12_-_57146095 1.04 ENST00000550770.1
ENST00000338193.6
primase, DNA, polypeptide 1 (49kDa)
chr22_-_42343117 1.04 ENST00000407253.3
ENST00000215980.5
centromere protein M
chr4_+_154265784 1.04 ENST00000240488.3
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr22_-_42342692 1.03 ENST00000404067.1
ENST00000402338.1
centromere protein M
chr2_-_26205340 1.02 ENST00000264712.3
kinesin family member 3C
chr7_-_21985656 1.01 ENST00000406877.3
cell division cycle associated 7-like
chr20_+_42295745 1.00 ENST00000396863.4
ENST00000217026.4
v-myb avian myeloblastosis viral oncogene homolog-like 2
chr11_+_58910295 1.00 ENST00000420244.1
family with sequence similarity 111, member A
chr7_-_99698338 0.96 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr3_+_160117418 0.96 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
structural maintenance of chromosomes 4
chr15_+_48624300 0.95 ENST00000455976.2
ENST00000559540.1
deoxyuridine triphosphatase
chr9_+_35732312 0.94 ENST00000353704.2
cAMP responsive element binding protein 3
chr4_+_128802016 0.90 ENST00000270861.5
ENST00000515069.1
ENST00000513090.1
ENST00000507249.1
polo-like kinase 4
chr12_+_49717019 0.89 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
trophinin associated protein
chr4_+_178230985 0.89 ENST00000264596.3
nei endonuclease VIII-like 3 (E. coli)
chr20_+_37554955 0.88 ENST00000217429.4
family with sequence similarity 83, member D
chr17_-_34890759 0.86 ENST00000431794.3
myosin XIX
chr5_-_43313574 0.85 ENST00000325110.6
ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr17_-_41277317 0.84 ENST00000497488.1
ENST00000489037.1
ENST00000470026.1
ENST00000586385.1
ENST00000591534.1
ENST00000591849.1
breast cancer 1, early onset
chr1_-_229761717 0.84 ENST00000366675.3
ENST00000258281.2
ENST00000366674.1
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr16_+_699319 0.84 ENST00000549091.1
ENST00000293879.4
WD repeat domain 90
chr12_-_57472522 0.83 ENST00000379391.3
ENST00000300128.4
transmembrane protein 194A
chr17_-_30185946 0.82 ENST00000579741.1
coordinator of PRMT5, differentiation stimulator
chr12_+_49717081 0.81 ENST00000547807.1
ENST00000551567.1
trophinin associated protein
chr11_-_118966167 0.80 ENST00000530167.1
H2A histone family, member X
chr14_+_50065376 0.77 ENST00000298288.6
leucine rich repeat protein 1
chr17_-_41277370 0.76 ENST00000476777.1
ENST00000491747.2
ENST00000478531.1
ENST00000477152.1
ENST00000357654.3
ENST00000493795.1
ENST00000493919.1
breast cancer 1, early onset
chr11_+_58910201 0.75 ENST00000528737.1
family with sequence similarity 111, member A
chr17_-_41277467 0.74 ENST00000494123.1
ENST00000346315.3
ENST00000309486.4
ENST00000468300.1
ENST00000354071.3
ENST00000352993.3
ENST00000471181.2
breast cancer 1, early onset
chr1_+_28844778 0.71 ENST00000411533.1
regulator of chromosome condensation 1
chr10_+_120967072 0.70 ENST00000392870.2
G protein-coupled receptor kinase 5
chr5_+_14664762 0.68 ENST00000284274.4
family with sequence similarity 105, member B
chr4_+_74702214 0.68 ENST00000226317.5
ENST00000515050.1
chemokine (C-X-C motif) ligand 6
chr12_+_102513950 0.66 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARP1 binding protein
chr6_+_167412835 0.66 ENST00000349556.4
FGFR1 oncogene partner
chr1_+_44398943 0.66 ENST00000372359.5
ENST00000414809.3
artemin
chr4_+_56815102 0.65 ENST00000257287.4
centrosomal protein 135kDa
chr1_+_173793777 0.64 ENST00000239457.5
aspartyl-tRNA synthetase 2, mitochondrial
chr15_+_40987327 0.64 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
RAD51 recombinase
chr15_-_50647370 0.63 ENST00000558970.1
ENST00000396464.3
ENST00000560825.1
GA binding protein transcription factor, beta subunit 1
chr9_+_17134980 0.63 ENST00000380647.3
centlein, centrosomal protein
chr1_-_47779762 0.62 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
SCL/TAL1 interrupting locus
chr5_+_156887027 0.62 ENST00000435489.2
ENST00000311946.7
NIPA-like domain containing 4
chr12_+_8850471 0.61 ENST00000535829.1
ENST00000357529.3
ribosomal modification protein rimK-like family member B
chr9_-_124990680 0.61 ENST00000541397.2
ENST00000560485.1
LIM homeobox 6
chr21_-_33651324 0.60 ENST00000290130.3
MIS18 kinetochore protein A
chr14_+_50065459 0.59 ENST00000318317.4
leucine rich repeat protein 1
chr1_+_44399466 0.58 ENST00000498139.2
ENST00000491846.1
artemin
chr6_-_62996066 0.56 ENST00000281156.4
KH domain containing, RNA binding, signal transduction associated 2
chr15_+_42841008 0.56 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS augmin-like complex, subunit 2
chr19_-_10444188 0.56 ENST00000293677.6
ribonucleoprotein, PTB-binding 1
chr14_+_105219437 0.56 ENST00000329967.6
ENST00000347067.5
ENST00000553810.1
SIVA1, apoptosis-inducing factor
chr3_-_148804275 0.56 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
helicase-like transcription factor
chr6_+_57182400 0.55 ENST00000607273.1
primase, DNA, polypeptide 2 (58kDa)
chr2_+_179059365 0.55 ENST00000190611.4
oxysterol binding protein-like 6
chr8_-_124408652 0.55 ENST00000287394.5
ATPase family, AAA domain containing 2
chr8_-_103136481 0.54 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
neurocalcin delta
chr20_+_47662805 0.54 ENST00000262982.2
ENST00000542325.1
CSE1 chromosome segregation 1-like (yeast)
chr9_-_124991124 0.54 ENST00000394319.4
ENST00000340587.3
LIM homeobox 6
chr4_-_120548779 0.54 ENST00000264805.5
phosphodiesterase 5A, cGMP-specific
chr12_+_102514019 0.53 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARP1 binding protein
chr19_+_50887585 0.53 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
polymerase (DNA directed), delta 1, catalytic subunit
chr10_-_118764862 0.52 ENST00000260777.10
KIAA1598
chr14_+_53019993 0.52 ENST00000542169.2
ENST00000555622.1
G protein-coupled receptor 137C
chr9_+_131709966 0.51 ENST00000372577.2
nucleoporin 188kDa
chr5_+_36152179 0.51 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr11_-_95657231 0.50 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
myotubularin related protein 2
chr3_+_10068095 0.50 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
Fanconi anemia, complementation group D2
chr21_-_44496441 0.50 ENST00000359624.3
ENST00000352178.5
cystathionine-beta-synthase
chr11_+_31531291 0.48 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr18_+_33767473 0.48 ENST00000261326.5
molybdenum cofactor sulfurase
chr20_-_35402123 0.48 ENST00000373740.3
ENST00000426836.1
ENST00000373745.3
ENST00000448110.2
ENST00000438549.1
ENST00000447406.1
ENST00000373750.4
ENST00000373734.4
DSN1, MIS12 kinetochore complex component
chr5_+_36152091 0.48 ENST00000274254.5
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr1_+_65210772 0.47 ENST00000371072.4
ENST00000294428.3
ribonucleoprotein, PTB-binding 2
chr16_+_838614 0.47 ENST00000262315.9
ENST00000455171.2
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr17_-_30185971 0.47 ENST00000378634.2
coordinator of PRMT5, differentiation stimulator
chr16_-_49315731 0.47 ENST00000219197.6
cerebellin 1 precursor
chr14_+_21538517 0.46 ENST00000298693.3
Rho guanine nucleotide exchange factor (GEF) 40
chr11_+_82612740 0.46 ENST00000524921.1
ENST00000528759.1
ENST00000525361.1
ENST00000430323.2
ENST00000533655.1
ENST00000532764.1
ENST00000532589.1
ENST00000525388.1
chromosome 11 open reading frame 82
chr9_+_131182697 0.45 ENST00000372838.4
ENST00000411852.1
cerebral endothelial cell adhesion molecule
chr19_-_31840438 0.45 ENST00000240587.4
teashirt zinc finger homeobox 3
chr2_-_38978492 0.43 ENST00000409276.1
ENST00000446327.2
ENST00000313117.6
serine/arginine-rich splicing factor 7
chr9_-_77567743 0.42 ENST00000376854.5
chromosome 9 open reading frame 40
chr5_+_36152163 0.42 ENST00000274255.6
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr15_-_50647347 0.42 ENST00000220429.8
ENST00000429662.2
GA binding protein transcription factor, beta subunit 1
chr9_-_131418944 0.42 ENST00000419989.1
ENST00000451652.1
ENST00000372715.2
WD repeat domain 34
chr6_-_139308777 0.42 ENST00000529597.1
ENST00000415951.2
ENST00000367663.4
ENST00000409812.2
RALBP1 associated Eps domain containing 1
chr17_+_77751931 0.42 ENST00000310942.4
ENST00000269399.5
chromobox homolog 2
chr14_+_53019822 0.41 ENST00000321662.6
G protein-coupled receptor 137C
chr15_-_50647274 0.40 ENST00000543881.1
GA binding protein transcription factor, beta subunit 1
chr7_-_73668692 0.39 ENST00000352131.3
ENST00000055077.3
replication factor C (activator 1) 2, 40kDa
chr19_+_55795493 0.39 ENST00000309383.1
BR serine/threonine kinase 1
chr5_-_149682447 0.39 ENST00000328668.7
arylsulfatase family, member I
chrX_+_30671476 0.38 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
glycerol kinase
chr20_-_35724388 0.38 ENST00000344359.3
ENST00000373664.3
retinoblastoma-like 1 (p107)
chr16_-_67693846 0.38 ENST00000602850.1
adrenocortical dysplasia homolog (mouse)
chr13_+_95254085 0.38 ENST00000376958.4
G protein-coupled receptor 180
chr6_-_139309378 0.38 ENST00000450536.2
ENST00000258062.5
RALBP1 associated Eps domain containing 1
chr2_-_128785688 0.38 ENST00000259234.6
Sin3A-associated protein, 130kDa
chr1_+_173793641 0.37 ENST00000361951.4
aspartyl-tRNA synthetase 2, mitochondrial
chr2_+_48010312 0.37 ENST00000540021.1
mutS homolog 6
chr6_-_19804973 0.37 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
chr4_-_120549163 0.37 ENST00000394439.1
ENST00000420633.1
phosphodiesterase 5A, cGMP-specific
chr4_+_331578 0.37 ENST00000512994.1
zinc finger protein 141
chrX_+_100353153 0.37 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
centromere protein I
chr5_-_79950371 0.36 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
dihydrofolate reductase
chrX_+_133594168 0.36 ENST00000298556.7
hypoxanthine phosphoribosyltransferase 1
chr10_+_82116529 0.36 ENST00000411538.1
ENST00000256039.2
DPY30 domain containing 2
chr4_-_122872909 0.36 ENST00000379645.3
transient receptor potential cation channel, subfamily C, member 3
chr5_+_149737202 0.35 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
Treacher Collins-Franceschetti syndrome 1
chr2_+_48010221 0.35 ENST00000234420.5
mutS homolog 6
chr7_+_77428149 0.34 ENST00000415251.2
ENST00000275575.7
putative homeodomain transcription factor 2
chr6_+_135502466 0.34 ENST00000367814.4
v-myb avian myeloblastosis viral oncogene homolog
chr8_-_101157680 0.33 ENST00000428847.2
F-box protein 43
chr9_-_23821842 0.33 ENST00000544538.1
ELAV like neuron-specific RNA binding protein 2
chr7_+_77428066 0.32 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
putative homeodomain transcription factor 2
chr14_+_21538429 0.32 ENST00000298694.4
ENST00000555038.1
Rho guanine nucleotide exchange factor (GEF) 40
chr4_+_155665123 0.32 ENST00000336356.3
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr22_+_20105012 0.32 ENST00000331821.3
ENST00000411892.1
RAN binding protein 1
chr2_-_17935059 0.31 ENST00000448223.2
ENST00000381272.4
ENST00000351948.4
structural maintenance of chromosomes 6
chrX_+_14891522 0.31 ENST00000380492.3
ENST00000482354.1
motile sperm domain containing 2
chr4_+_175204818 0.30 ENST00000503780.1
centrosomal protein 44kDa
chr6_+_135502408 0.30 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
v-myb avian myeloblastosis viral oncogene homolog
chr1_-_10003372 0.30 ENST00000377223.1
ENST00000541052.1
ENST00000377213.1
leucine zipper and CTNNBIP1 domain containing
chrX_-_125686784 0.30 ENST00000371126.1
DDB1 and CUL4 associated factor 12-like 1
chr19_+_13049413 0.30 ENST00000316448.5
ENST00000588454.1
calreticulin
chr13_-_113862948 0.30 ENST00000375457.2
ENST00000375477.1
ENST00000246505.5
ENST00000337344.4
ENST00000375479.2
PCI domain containing 2
chr16_-_67694129 0.29 ENST00000602320.1
adrenocortical dysplasia homolog (mouse)
chr3_+_180630090 0.29 ENST00000357559.4
ENST00000305586.7
fragile X mental retardation, autosomal homolog 1
chr17_-_74722536 0.29 ENST00000585429.1
jumonji domain containing 6
chr6_-_110012380 0.29 ENST00000424296.2
ENST00000341338.6
ENST00000368948.2
ENST00000285397.5
adenylate kinase 9
chr2_+_204192942 0.28 ENST00000295851.5
ENST00000261017.5
abl-interactor 2
chr17_+_73008755 0.28 ENST00000584208.1
ENST00000301585.5
immature colon carcinoma transcript 1
chr1_+_28844648 0.28 ENST00000373832.1
ENST00000373831.3
regulator of chromosome condensation 1
chr11_-_118972575 0.28 ENST00000432443.2
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr15_-_42840961 0.28 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
leucine rich repeat containing 57
chr12_+_56521840 0.27 ENST00000394048.5
extended synaptotagmin-like protein 1
chr3_+_128598433 0.27 ENST00000308982.7
ENST00000514336.1
acyl-CoA dehydrogenase family, member 9
chr12_-_102513843 0.27 ENST00000551744.2
ENST00000552283.1
nucleoporin 37kDa
chr13_+_32889605 0.27 ENST00000380152.3
ENST00000544455.1
ENST00000530893.2
breast cancer 2, early onset
chr11_-_119234876 0.27 ENST00000525735.1
ubiquitin specific peptidase 2
chr2_-_133427767 0.27 ENST00000397463.2
LY6/PLAUR domain containing 1
chr2_+_47630255 0.26 ENST00000406134.1
mutS homolog 2
chr2_+_154728426 0.26 ENST00000392825.3
ENST00000434213.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr1_+_84543734 0.26 ENST00000370689.2
protein kinase, cAMP-dependent, catalytic, beta
chr19_+_50180317 0.26 ENST00000534465.1
protein arginine methyltransferase 1
chr9_-_27573392 0.25 ENST00000380003.3
chromosome 9 open reading frame 72
chr3_-_33759541 0.25 ENST00000468888.2
cytoplasmic linker associated protein 2
chrX_-_14891150 0.25 ENST00000452869.1
ENST00000398334.1
ENST00000324138.3
Fanconi anemia, complementation group B
chr11_-_31531121 0.24 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr1_-_155947951 0.24 ENST00000313695.7
ENST00000497907.1
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr1_+_240255166 0.24 ENST00000319653.9
formin 2
chr1_+_173837488 0.24 ENST00000427304.1
ENST00000432989.1
ENST00000367702.1
zinc finger and BTB domain containing 37
chr16_-_67694597 0.24 ENST00000393919.4
ENST00000219251.8
adrenocortical dysplasia homolog (mouse)
chr8_+_124084899 0.24 ENST00000287380.1
ENST00000309336.3
ENST00000519418.1
ENST00000327098.5
ENST00000522420.1
ENST00000521676.1
ENST00000378080.2
TBC1 domain family, member 31
chr3_-_33759699 0.24 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
cytoplasmic linker associated protein 2
chr18_-_658244 0.23 ENST00000585033.1
ENST00000323813.3
chromosome 18 open reading frame 56
chr1_+_10490127 0.23 ENST00000602787.1
ENST00000602296.1
ENST00000400900.2
apoptosis-inducing, TAF9-like domain 1
APITD1-CORT readthrough
chr4_+_331619 0.23 ENST00000505939.1
ENST00000240499.7
zinc finger protein 141
chr1_+_10490441 0.23 ENST00000470413.2
ENST00000309048.3
APITD1-CORT readthrough
apoptosis-inducing, TAF9-like domain 1
chr6_+_167412665 0.22 ENST00000366847.4
FGFR1 oncogene partner
chr16_+_11439286 0.22 ENST00000312499.5
ENST00000576027.1
RecQ mediated genome instability 2
chr17_-_74722672 0.22 ENST00000397625.4
ENST00000445478.2
jumonji domain containing 6
chr7_-_30544405 0.22 ENST00000409390.1
ENST00000409144.1
ENST00000005374.6
ENST00000409436.1
ENST00000275428.4
gamma-glutamylcyclotransferase
chr2_+_68384976 0.22 ENST00000263657.2
partner of NOB1 homolog (S. cerevisiae)
chr2_+_47630108 0.22 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
mutS homolog 2
chr2_+_178077477 0.22 ENST00000411529.2
ENST00000435711.1
heterogeneous nuclear ribonucleoprotein A3

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.8 1.6 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.8 2.3 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.7 5.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.7 2.0 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.6 2.2 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.4 1.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.4 2.5 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.4 2.5 GO:0072757 cellular response to camptothecin(GO:0072757)
0.4 1.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.3 3.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 0.9 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.3 0.9 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.3 2.0 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.3 1.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.3 1.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 1.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.2 1.0 GO:0072719 cellular response to cisplatin(GO:0072719)
0.2 0.6 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 1.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.2 0.9 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.2 0.9 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.2 0.5 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.2 1.7 GO:0007144 female meiosis I(GO:0007144)
0.2 0.9 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 1.5 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 1.0 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 1.5 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.4 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.5 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 4.5 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.4 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.4 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 1.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 1.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 3.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.5 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 0.3 GO:0061567 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.5 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 0.4 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 1.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.5 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 1.1 GO:0009650 UV protection(GO:0009650)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.2 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 1.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 3.0 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.5 GO:0033504 floor plate development(GO:0033504)
0.1 0.2 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.1 0.1 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.4 GO:0097338 response to clozapine(GO:0097338)
0.1 0.5 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.4 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.3 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.6 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.5 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.1 0.2 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.2 GO:1903465 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.9 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.9 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.3 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.2 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 1.4 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.3 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.1 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.5 GO:0044351 macropinocytosis(GO:0044351) phagosome-lysosome fusion(GO:0090385)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0097107 postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.2 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 1.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:1904978 regulation of endosome organization(GO:1904978)
0.0 0.7 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.3 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.6 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.9 GO:0006284 base-excision repair(GO:0006284)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.2 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.2 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.2 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.7 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 1.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 1.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.8 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0000732 strand displacement(GO:0000732)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 1.1 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.4 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.6 GO:0006301 postreplication repair(GO:0006301)
0.0 1.4 GO:0051225 spindle assembly(GO:0051225)
0.0 4.2 GO:0006413 translational initiation(GO:0006413)
0.0 0.3 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 1.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.5 1.4 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.5 2.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.4 1.8 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.3 1.0 GO:0031523 Myb complex(GO:0031523)
0.3 1.2 GO:0032301 MutSalpha complex(GO:0032301)
0.2 1.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 2.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 2.8 GO:0000800 lateral element(GO:0000800)
0.2 3.1 GO:0042555 MCM complex(GO:0042555)
0.2 1.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 2.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 0.9 GO:0098536 deuterosome(GO:0098536)
0.2 1.6 GO:0008278 cohesin complex(GO:0008278)
0.2 2.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 1.5 GO:0036449 microtubule minus-end(GO:0036449)
0.2 0.5 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.1 1.9 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 1.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.0 GO:0000796 condensin complex(GO:0000796)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.9 GO:0070187 telosome(GO:0070187)
0.1 4.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.1 1.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.9 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.6 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.8 GO:0030914 STAGA complex(GO:0030914)
0.0 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.0 0.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 3.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.4 GO:0045120 pronucleus(GO:0045120)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 3.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.1 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 2.0 GO:0005814 centriole(GO:0005814)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.4 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.5 GO:0000793 condensed chromosome(GO:0000793)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0004797 thymidine kinase activity(GO:0004797)
0.5 2.3 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.4 1.6 GO:0003896 DNA primase activity(GO:0003896)
0.4 3.8 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.3 2.8 GO:0000405 bubble DNA binding(GO:0000405)
0.3 0.9 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.3 1.2 GO:0032143 single thymine insertion binding(GO:0032143)
0.3 4.0 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.3 1.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 0.7 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 1.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 1.0 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.2 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 0.5 GO:0004122 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.2 1.5 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.4 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 1.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 1.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.5 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 0.9 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 3.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 1.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.2 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.1 1.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.4 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 4.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 4.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.0 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.9 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.3 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.7 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 1.0 GO:0003682 chromatin binding(GO:0003682)
0.0 1.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.7 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 1.1 PID ATR PATHWAY ATR signaling pathway
0.1 6.7 PID E2F PATHWAY E2F transcription factor network
0.0 1.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.5 PID AURORA A PATHWAY Aurora A signaling
0.0 1.4 PID MYC PATHWAY C-MYC pathway
0.0 0.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 2.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.8 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.4 6.8 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.3 8.9 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.2 4.1 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 3.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 2.9 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 3.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 4.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.0 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 2.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.8 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 2.0 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.6 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines