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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for E4F1

Z-value: 0.35

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Transcription factors associated with E4F1

Gene Symbol Gene ID Gene Info
E4F1
ENSG00000167967.11 E4F transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E4F1hg19_v2_chr16_+_2273558_2273637-0.096.2e-01Click!

Activity profile of E4F1 motif

Sorted Z-values of E4F1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_216300784 1.62 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr4_+_75310851 0.88 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr4_+_75311019 0.85 ENST00000502307.1
AREG
amphiregulin
chr20_+_34203794 0.59 ENST00000374273.3
SPAG4
sperm associated antigen 4
chr19_+_1941117 0.56 ENST00000255641.8
CSNK1G2
casein kinase 1, gamma 2
chr17_+_41476327 0.56 ENST00000320033.4
ARL4D
ADP-ribosylation factor-like 4D
chr1_-_8086343 0.52 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERRFI1
ERBB receptor feedback inhibitor 1
chr10_+_95256356 0.48 ENST00000371485.3
CEP55
centrosomal protein 55kDa
chr20_+_58179582 0.47 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr4_-_122744998 0.43 ENST00000274026.5
CCNA2
cyclin A2
chr12_+_107168342 0.39 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr20_-_44420507 0.37 ENST00000243938.4
WFDC3
WAP four-disulfide core domain 3
chr12_+_107168418 0.36 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr6_+_64282447 0.33 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr20_-_5591626 0.33 ENST00000379019.4
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr20_+_44420570 0.33 ENST00000372622.3
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr3_+_150126101 0.33 ENST00000361875.3
ENST00000361136.2
TSC22D2
TSC22 domain family, member 2
chr9_-_131644202 0.31 ENST00000320665.6
ENST00000436267.2
CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chr20_+_44420617 0.31 ENST00000449078.1
ENST00000456939.1
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr9_-_131644306 0.30 ENST00000302586.3
CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chr17_-_36831156 0.29 ENST00000325814.5
C17orf96
chromosome 17 open reading frame 96
chr9_+_131644398 0.29 ENST00000372599.3
LRRC8A
leucine rich repeat containing 8 family, member A
chr8_-_29208183 0.28 ENST00000240100.2
DUSP4
dual specificity phosphatase 4
chr3_+_38206975 0.28 ENST00000446845.1
ENST00000311806.3
OXSR1
oxidative stress responsive 1
chr6_-_53213587 0.28 ENST00000542638.1
ENST00000370913.5
ENST00000541407.1
ELOVL5
ELOVL fatty acid elongase 5
chr1_-_32110467 0.27 ENST00000440872.2
ENST00000373703.4
PEF1
penta-EF-hand domain containing 1
chr9_+_131644781 0.26 ENST00000259324.5
LRRC8A
leucine rich repeat containing 8 family, member A
chr9_+_131644388 0.26 ENST00000372600.4
LRRC8A
leucine rich repeat containing 8 family, member A
chr17_+_25621102 0.25 ENST00000581440.1
ENST00000262394.2
ENST00000583742.1
ENST00000579733.1
ENST00000583193.1
ENST00000581185.1
ENST00000427287.2
ENST00000348811.2
WSB1
WD repeat and SOCS box containing 1
chr6_+_30029008 0.25 ENST00000332435.5
ENST00000376782.2
ENST00000359374.4
ENST00000376785.2
ZNRD1
zinc ribbon domain containing 1
chr19_+_45349432 0.25 ENST00000252485.4
PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr11_+_66188475 0.24 ENST00000311034.2
NPAS4
neuronal PAS domain protein 4
chr1_+_39456895 0.23 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1
akirin 1
chr6_+_64281906 0.22 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr6_+_28048753 0.22 ENST00000377325.1
ZNF165
zinc finger protein 165
chr6_-_163148700 0.22 ENST00000366894.1
ENST00000338468.3
PARK2
parkin RBR E3 ubiquitin protein ligase
chr3_+_185304059 0.21 ENST00000427465.2
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr2_-_220408430 0.21 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr11_-_67276100 0.21 ENST00000301488.3
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr8_-_98290087 0.19 ENST00000322128.3
TSPYL5
TSPY-like 5
chr17_+_71161140 0.19 ENST00000357585.2
SSTR2
somatostatin receptor 2
chr6_-_163148780 0.19 ENST00000366892.1
ENST00000366898.1
ENST00000366897.1
ENST00000366896.1
PARK2
parkin RBR E3 ubiquitin protein ligase
chr6_+_47445467 0.19 ENST00000359314.5
CD2AP
CD2-associated protein
chr8_-_66754172 0.18 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr14_+_94492674 0.18 ENST00000203664.5
ENST00000553723.1
OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr17_+_7211656 0.18 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr4_-_186456652 0.16 ENST00000284767.5
ENST00000284770.5
PDLIM3
PDZ and LIM domain 3
chr4_-_186456766 0.16 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr9_+_125027127 0.16 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
MRRF
mitochondrial ribosome recycling factor
chr7_-_140624499 0.15 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr10_+_64893039 0.15 ENST00000277746.6
ENST00000435510.2
NRBF2
nuclear receptor binding factor 2
chr19_+_54705025 0.15 ENST00000441429.1
RPS9
ribosomal protein S9
chr7_-_129592471 0.15 ENST00000473814.2
ENST00000490974.1
UBE2H
ubiquitin-conjugating enzyme E2H
chr10_-_50970322 0.15 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr11_-_33183006 0.15 ENST00000524827.1
ENST00000323959.4
ENST00000431742.2
CSTF3
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
chr7_-_129592700 0.14 ENST00000472396.1
ENST00000355621.3
UBE2H
ubiquitin-conjugating enzyme E2H
chr6_-_31774714 0.14 ENST00000375661.5
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr10_-_50970382 0.14 ENST00000419399.1
ENST00000432695.1
OGDHL
oxoglutarate dehydrogenase-like
chr6_+_26204825 0.14 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr22_+_18121356 0.14 ENST00000317582.5
ENST00000543133.1
ENST00000538149.1
ENST00000337612.5
ENST00000493680.1
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr6_+_33176265 0.13 ENST00000374656.4
RING1
ring finger protein 1
chr8_+_94929110 0.13 ENST00000520728.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr8_-_95274536 0.13 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr9_+_125026882 0.13 ENST00000297908.3
ENST00000373730.3
ENST00000546115.1
ENST00000344641.3
MRRF
mitochondrial ribosome recycling factor
chr1_+_180199393 0.12 ENST00000263726.2
LHX4
LIM homeobox 4
chr11_+_111411384 0.12 ENST00000375615.3
ENST00000525126.1
ENST00000436913.2
ENST00000533265.1
LAYN
layilin
chr19_+_54704718 0.11 ENST00000391752.1
ENST00000402367.1
ENST00000391751.3
RPS9
ribosomal protein S9
chr17_+_35294075 0.11 ENST00000254457.5
LHX1
LIM homeobox 1
chr2_+_202899310 0.11 ENST00000286201.1
FZD7
frizzled family receptor 7
chr5_-_138210977 0.11 ENST00000274711.6
ENST00000521094.2
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr6_+_110299501 0.11 ENST00000414000.2
GPR6
G protein-coupled receptor 6
chr3_+_101292939 0.11 ENST00000265260.3
ENST00000469941.1
ENST00000296024.5
PCNP
PEST proteolytic signal containing nuclear protein
chr20_-_62258394 0.11 ENST00000370077.1
GMEB2
glucocorticoid modulatory element binding protein 2
chr4_+_1873100 0.11 ENST00000508803.1
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr16_-_27561209 0.10 ENST00000356183.4
ENST00000561623.1
GTF3C1
general transcription factor IIIC, polypeptide 1, alpha 220kDa
chr15_-_53082178 0.10 ENST00000305901.5
ONECUT1
one cut homeobox 1
chr4_-_104119528 0.10 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE
centromere protein E, 312kDa
chr6_-_34664612 0.10 ENST00000374023.3
ENST00000374026.3
C6orf106
chromosome 6 open reading frame 106
chr19_-_10341948 0.10 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
S1PR2
DNMT1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr3_-_156877997 0.10 ENST00000295926.3
CCNL1
cyclin L1
chr8_+_94929168 0.10 ENST00000518107.1
ENST00000396200.3
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr6_+_44355257 0.10 ENST00000371477.3
CDC5L
cell division cycle 5-like
chr22_+_39101728 0.10 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chr17_-_7165662 0.10 ENST00000571881.2
ENST00000360325.7
CLDN7
claudin 7
chr4_-_76598544 0.10 ENST00000515457.1
ENST00000357854.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr11_+_4116005 0.09 ENST00000300738.5
RRM1
ribonucleotide reductase M1
chr19_+_54704610 0.09 ENST00000302907.4
RPS9
ribosomal protein S9
chr1_+_212208919 0.09 ENST00000366991.4
ENST00000542077.1
DTL
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr19_+_54704990 0.09 ENST00000391753.2
RPS9
ribosomal protein S9
chr8_+_94929077 0.09 ENST00000297598.4
ENST00000520614.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr11_+_4116054 0.08 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr22_+_18121562 0.08 ENST00000355028.3
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr1_-_47184745 0.08 ENST00000544071.1
EFCAB14
EF-hand calcium binding domain 14
chr22_-_41252962 0.08 ENST00000216218.3
ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr15_-_41047421 0.08 ENST00000560460.1
ENST00000338376.3
ENST00000560905.1
RMDN3
regulator of microtubule dynamics 3
chr11_-_8680383 0.07 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr17_-_80231300 0.07 ENST00000398519.5
ENST00000580446.1
CSNK1D
casein kinase 1, delta
chr6_-_144416737 0.07 ENST00000367569.2
SF3B5
splicing factor 3b, subunit 5, 10kDa
chr11_+_66059339 0.07 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chrX_+_152224766 0.07 ENST00000370265.4
ENST00000447306.1
PNMA3
paraneoplastic Ma antigen 3
chr18_+_23806437 0.07 ENST00000578121.1
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr2_-_240964716 0.06 ENST00000404554.1
ENST00000407129.3
ENST00000307300.4
ENST00000443626.1
ENST00000252711.2
NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr17_-_80231557 0.06 ENST00000392334.2
ENST00000314028.6
CSNK1D
casein kinase 1, delta
chr4_-_111558135 0.06 ENST00000394598.2
ENST00000394595.3
PITX2
paired-like homeodomain 2
chr12_-_110011288 0.06 ENST00000540016.1
ENST00000266839.5
MMAB
methylmalonic aciduria (cobalamin deficiency) cblB type
chr6_-_27440460 0.06 ENST00000377419.1
ZNF184
zinc finger protein 184
chr1_-_16482554 0.06 ENST00000358432.5
EPHA2
EPH receptor A2
chr3_+_185303962 0.05 ENST00000296257.5
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr17_+_39845134 0.05 ENST00000591776.1
ENST00000469257.1
EIF1
eukaryotic translation initiation factor 1
chr1_+_2004901 0.05 ENST00000400921.2
PRKCZ
protein kinase C, zeta
chr1_+_2005425 0.05 ENST00000461106.2
PRKCZ
protein kinase C, zeta
chr14_-_50053081 0.05 ENST00000396020.3
ENST00000245458.6
RPS29
ribosomal protein S29
chr19_+_52693259 0.04 ENST00000322088.6
ENST00000454220.2
ENST00000444322.2
ENST00000477989.1
PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr2_-_62115659 0.04 ENST00000544185.1
CCT4
chaperonin containing TCP1, subunit 4 (delta)
chr12_+_111471828 0.04 ENST00000261726.6
CUX2
cut-like homeobox 2
chr17_+_7476136 0.04 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
EIF4A1
eukaryotic translation initiation factor 4A1
chr1_-_47184723 0.04 ENST00000371933.3
EFCAB14
EF-hand calcium binding domain 14
chr22_-_38902300 0.04 ENST00000403230.1
DDX17
DEAD (Asp-Glu-Ala-Asp) box helicase 17
chr11_-_33183048 0.04 ENST00000438862.2
CSTF3
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
chr16_+_68057153 0.04 ENST00000358896.6
ENST00000568099.2
DUS2
dihydrouridine synthase 2
chr20_-_44600810 0.04 ENST00000322927.2
ENST00000426788.1
ZNF335
zinc finger protein 335
chr2_-_62115725 0.04 ENST00000538252.1
ENST00000544079.1
ENST00000394440.3
CCT4
chaperonin containing TCP1, subunit 4 (delta)
chr6_-_27440837 0.03 ENST00000211936.6
ZNF184
zinc finger protein 184
chrX_+_153672468 0.03 ENST00000393600.3
FAM50A
family with sequence similarity 50, member A
chr1_+_8378140 0.03 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chr16_+_68056844 0.03 ENST00000565263.1
DUS2
dihydrouridine synthase 2
chrX_-_153236819 0.02 ENST00000354233.3
HCFC1
host cell factor C1 (VP16-accessory protein)
chr10_-_64576105 0.02 ENST00000242480.3
ENST00000411732.1
EGR2
early growth response 2
chr16_+_68057179 0.02 ENST00000567100.1
ENST00000432752.1
ENST00000569289.1
ENST00000564781.1
DUS2
dihydrouridine synthase 2
chr3_-_101395936 0.02 ENST00000461821.1
ZBTB11
zinc finger and BTB domain containing 11
chr17_-_40540484 0.01 ENST00000588969.1
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr17_-_40540586 0.01 ENST00000264657.5
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr16_+_29911666 0.01 ENST00000563177.1
ENST00000483405.1
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr11_-_6633799 0.01 ENST00000299424.4
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr5_+_68513557 0.01 ENST00000256441.4
MRPS36
mitochondrial ribosomal protein S36
chr17_+_42385927 0.01 ENST00000426726.3
ENST00000590941.1
ENST00000225441.7
RUNDC3A
RUN domain containing 3A
chrX_-_153237258 0.01 ENST00000310441.7
HCFC1
host cell factor C1 (VP16-accessory protein)
chr5_-_95297678 0.00 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr17_+_685513 0.00 ENST00000304478.4
RNMTL1
RNA methyltransferase like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of E4F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 1.7 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.4 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 0.2 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.1 GO:0060067 cervix development(GO:0060067)
0.1 0.3 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.8 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.5 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.1 GO:0009996 negative regulation of cell fate specification(GO:0009996)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.6 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:1901491 axial mesoderm formation(GO:0048320) negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.3 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.0 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 1.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.2 GO:0097447 dendritic tree(GO:0097447)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.5 GO:0090543 Flemming body(GO:0090543)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 2.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.4 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0001003 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 1.8 GO:0016504 peptidase activator activity(GO:0016504)
0.0 1.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism