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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for EBF1
Z-value: 0.98
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Transcription factors associated with EBF1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| EBF1 | hg19_v2_chr5_-_158526756_158526797 | 0.18 | 3.5e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of EBF1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 4.7 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 0.0 | 2.4 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.3 | 2.1 | GO:0010731 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
| 0.1 | 2.1 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 0.1 | 2.0 | GO:0006068 | ethanol catabolic process(GO:0006068) |
| 0.3 | 1.9 | GO:1990822 | basic amino acid transmembrane transport(GO:1990822) |
| 0.3 | 1.8 | GO:0045007 | depurination(GO:0045007) |
| 0.3 | 1.7 | GO:0072244 | metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) |
| 0.5 | 1.5 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
| 0.3 | 1.5 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.1 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.0 | 2.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.8 | GO:0034705 | potassium channel complex(GO:0034705) |
| 0.2 | 1.5 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.1 | 1.5 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 1.5 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.1 | 1.4 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 1.3 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.4 | 1.2 | GO:0005608 | laminin-3 complex(GO:0005608) |
| 0.1 | 1.2 | GO:0097227 | sperm annulus(GO:0097227) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.9 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.0 | 2.7 | GO:0005254 | chloride channel activity(GO:0005254) |
| 0.0 | 2.6 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.4 | 1.8 | GO:0032408 | MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408) |
| 0.1 | 1.8 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.4 | 1.7 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 0.2 | 1.7 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.1 | 1.6 | GO:0019864 | IgG binding(GO:0019864) |
| 0.0 | 1.6 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.0 | 1.6 | GO:0030507 | spectrin binding(GO:0030507) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.8 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 1.5 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 1.0 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 0.9 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 0.8 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.8 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 0.8 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 0.7 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 0.7 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 0.6 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.4 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 2.1 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 2.1 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 1.9 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 1.8 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 1.7 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 1.4 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 1.3 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 1.3 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 1.3 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |