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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for EMX2

Z-value: 0.52

Motif logo

Transcription factors associated with EMX2

Gene Symbol Gene ID Gene Info
ENSG00000170370.10 empty spiracles homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EMX2hg19_v2_chr10_+_119301928_119301955-0.058.1e-01Click!

Activity profile of EMX2 motif

Sorted Z-values of EMX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_63638339 3.70 ENST00000343837.3
ENST00000469440.1
sentan, cilia apical structure protein
chr4_-_100356551 2.83 ENST00000209665.4
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr6_-_33041378 2.21 ENST00000428995.1
major histocompatibility complex, class II, DP alpha 1
chr4_-_100356291 1.95 ENST00000476959.1
ENST00000482593.1
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr2_+_228736335 1.90 ENST00000440997.1
ENST00000545118.1
dynein assembly factor with WDR repeat domains 1
chr11_-_26593779 1.71 ENST00000529533.1
mucin 15, cell surface associated
chr21_-_43735628 1.53 ENST00000291525.10
ENST00000518498.1
trefoil factor 3 (intestinal)
chr5_-_137475071 1.38 ENST00000265191.2
NME/NM23 family member 5
chr11_-_63376013 1.38 ENST00000540943.1
phospholipase A2, group XVI
chr11_-_26593677 1.38 ENST00000527569.1
mucin 15, cell surface associated
chr11_-_26593649 1.32 ENST00000455601.2
mucin 15, cell surface associated
chr19_-_41388657 1.32 ENST00000301146.4
ENST00000291764.3
cytochrome P450, family 2, subfamily A, polypeptide 7
chr21_-_43735446 1.32 ENST00000398431.2
trefoil factor 3 (intestinal)
chr12_-_68696652 1.22 ENST00000539972.1
Mdm1 nuclear protein homolog (mouse)
chr16_-_28634874 1.20 ENST00000395609.1
ENST00000350842.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr12_-_71533055 1.15 ENST00000552128.1
tetraspanin 8
chr3_+_113616317 1.13 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr8_-_133687813 1.03 ENST00000250173.1
ENST00000519595.1
leucine rich repeat containing 6
chr1_-_86848760 1.03 ENST00000460698.2
outer dense fiber of sperm tails 2-like
chr8_-_133687778 0.98 ENST00000518642.1
leucine rich repeat containing 6
chr1_+_36549676 0.90 ENST00000207457.3
tektin 2 (testicular)
chr1_+_79115503 0.87 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
interferon-induced protein 44
chr6_-_52705641 0.86 ENST00000370989.2
glutathione S-transferase alpha 5
chr1_+_170904612 0.86 ENST00000367759.4
ENST00000367758.3
maestro heat-like repeat family member 9
chr3_+_130745688 0.85 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NIMA-related kinase 11
chr6_+_27833034 0.83 ENST00000357320.2
histone cluster 1, H2al
chrX_+_36254051 0.76 ENST00000378657.4
chromosome X open reading frame 30
chr22_-_51222070 0.73 ENST00000395593.3
ENST00000395598.3
ENST00000435118.1
ENST00000395591.1
ENST00000395595.3
RAB, member of RAS oncogene family-like 2B
chr5_-_111093167 0.73 ENST00000446294.2
ENST00000419114.2
neuronal regeneration related protein
chr11_+_27076764 0.69 ENST00000525090.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr3_-_122512619 0.66 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr6_-_109761707 0.64 ENST00000520723.1
ENST00000518648.1
ENST00000417394.2
peptidylprolyl isomerase (cyclophilin)-like 6
chr12_-_10282836 0.63 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
C-type lectin domain family 7, member A
chr2_-_99279928 0.63 ENST00000414521.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr11_+_66276550 0.60 ENST00000419755.3
Bardet-Biedl syndrome 1 protein
chr14_+_74034310 0.60 ENST00000538782.1
acyl-CoA thioesterase 2
chr5_-_111092930 0.56 ENST00000257435.7
neuronal regeneration related protein
chr7_+_90338712 0.55 ENST00000265741.3
ENST00000406263.1
cyclin-dependent kinase 14
chr5_-_111312622 0.53 ENST00000395634.3
neuronal regeneration related protein
chr19_+_58144529 0.52 ENST00000347302.3
ENST00000254182.7
ENST00000391703.3
ENST00000541801.1
ENST00000299871.5
ENST00000544273.1
zinc finger protein 211
chr6_-_76072719 0.52 ENST00000370020.1
filamin A interacting protein 1
chr13_-_70682590 0.51 ENST00000377844.4
kelch-like family member 1
chr19_+_49199209 0.51 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
fucosyltransferase 2 (secretor status included)
chr6_+_150690028 0.51 ENST00000229447.5
ENST00000344419.3
iodotyrosine deiodinase
chr1_-_35450897 0.50 ENST00000373337.3
ZMYM6 neighbor
chrX_+_144908928 0.50 ENST00000408967.2
transmembrane protein 257
chr12_+_9980113 0.50 ENST00000537723.1
killer cell lectin-like receptor subfamily F, member 1
chr15_+_84115868 0.49 ENST00000427482.2
SH3-domain GRB2-like 3
chr5_-_111093081 0.48 ENST00000453526.2
ENST00000509427.1
neuronal regeneration related protein
chr4_-_25865159 0.48 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr4_+_74702214 0.48 ENST00000226317.5
ENST00000515050.1
chemokine (C-X-C motif) ligand 6
chr4_+_56212270 0.48 ENST00000264228.4
steroid 5 alpha-reductase 3
chr4_-_138453559 0.47 ENST00000511115.1
protocadherin 18
chr8_+_110552831 0.46 ENST00000530629.1
estrogen receptor binding site associated, antigen, 9
chr6_-_134639180 0.46 ENST00000367858.5
serum/glucocorticoid regulated kinase 1
chr14_+_51338816 0.46 ENST00000353130.1
ENST00000337334.2
ENST00000395752.1
abhydrolase domain containing 12B
chr12_-_10282742 0.46 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
C-type lectin domain family 7, member A
chr12_+_21207503 0.45 ENST00000545916.1
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr16_-_28937027 0.45 ENST00000358201.4
rabaptin, RAB GTPase binding effector protein 2
chr12_-_10282681 0.45 ENST00000533022.1
C-type lectin domain family 7, member A
chr19_+_50016610 0.43 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr16_+_69599861 0.42 ENST00000354436.2
nuclear factor of activated T-cells 5, tonicity-responsive
chr15_-_57025759 0.42 ENST00000267807.7
zinc finger protein 280D
chr19_-_35264089 0.41 ENST00000588760.1
ENST00000329285.8
ENST00000587354.2
zinc finger protein 599
chrX_+_55744228 0.40 ENST00000262850.7
Ras-related GTP binding B
chr5_-_41213607 0.39 ENST00000337836.5
ENST00000433294.1
complement component 6
chr14_+_102276132 0.38 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
protein phosphatase 2, regulatory subunit B', gamma
chr3_-_130745571 0.37 ENST00000514044.1
ENST00000264992.3
asteroid homolog 1 (Drosophila)
chr6_-_26235206 0.37 ENST00000244534.5
histone cluster 1, H1d
chr12_-_122985067 0.36 ENST00000540586.1
ENST00000543897.1
zinc finger, CCHC domain containing 8
chr4_-_186877806 0.36 ENST00000355634.5
sorbin and SH3 domain containing 2
chrX_+_55744166 0.36 ENST00000374941.4
ENST00000414239.1
Ras-related GTP binding B
chr6_+_116421976 0.35 ENST00000319550.4
ENST00000419791.1
5'-nucleotidase domain containing 1
chr4_+_56212505 0.35 ENST00000505210.1
steroid 5 alpha-reductase 3
chr15_-_75748115 0.35 ENST00000360439.4
SIN3 transcription regulator family member A
chr7_-_73153178 0.35 ENST00000437775.2
ENST00000222800.3
abhydrolase domain containing 11
chr4_-_186877502 0.35 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
sorbin and SH3 domain containing 2
chr12_-_100656134 0.34 ENST00000548313.1
DEP domain containing 4
chr11_-_128894053 0.33 ENST00000392657.3
Rho GTPase activating protein 32
chr3_+_132316081 0.33 ENST00000249887.2
atypical chemokine receptor 4
chr16_-_28374829 0.33 ENST00000532254.1
nuclear pore complex interacting protein family, member B6
chr8_+_110552337 0.32 ENST00000337573.5
estrogen receptor binding site associated, antigen, 9
chr3_-_49466686 0.31 ENST00000273598.3
ENST00000436744.2
nicolin 1
chrX_+_77166172 0.31 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chr3_+_140981456 0.31 ENST00000504264.1
acid phosphatase-like 2
chr21_-_43346790 0.30 ENST00000329623.7
C2 calcium-dependent domain containing 2
chr4_-_168155169 0.30 ENST00000534949.1
ENST00000535728.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr5_+_112312416 0.30 ENST00000389063.2
decapping mRNA 2
chr8_-_144660771 0.29 ENST00000449291.2
nicotinate phosphoribosyltransferase domain containing 1
chr16_+_31885079 0.29 ENST00000300870.10
ENST00000394846.3
zinc finger protein 267
chr5_+_140514782 0.29 ENST00000231134.5
protocadherin beta 5
chr8_+_67687413 0.28 ENST00000521960.1
ENST00000522398.1
ENST00000522629.1
ENST00000520976.1
ENST00000396596.1
serum/glucocorticoid regulated kinase family, member 3
chr1_-_67142710 0.28 ENST00000502413.2
Uncharacterized protein
chr2_-_62733476 0.28 ENST00000335390.5
transmembrane protein 17
chr5_-_55412774 0.28 ENST00000434982.2
ankyrin repeat domain 55
chr1_-_54405773 0.27 ENST00000371376.1
heat shock protein family B (small), member 11
chr16_+_15489603 0.27 ENST00000568766.1
ENST00000287594.7
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chr12_-_58220078 0.27 ENST00000549039.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr12_+_94071341 0.27 ENST00000542893.2
CASP2 and RIPK1 domain containing adaptor with death domain
chr6_+_28092338 0.27 ENST00000340487.4
zinc finger and SCAN domain containing 16
chr1_+_174844645 0.26 ENST00000486220.1
RAB GTPase activating protein 1-like
chr11_+_10476851 0.26 ENST00000396553.2
adenosine monophosphate deaminase 3
chr2_-_207024233 0.25 ENST00000423725.1
ENST00000233190.6
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr15_-_78913628 0.24 ENST00000348639.3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr19_-_14945933 0.24 ENST00000322301.3
olfactory receptor, family 7, subfamily A, member 5
chr12_+_94071129 0.24 ENST00000552983.1
ENST00000332896.3
ENST00000552033.1
ENST00000548483.1
CASP2 and RIPK1 domain containing adaptor with death domain
chr1_+_159931002 0.24 ENST00000443364.1
ENST00000423943.1
long intergenic non-protein coding RNA 1133
chr2_+_56179262 0.24 ENST00000606639.1
RP11-481J13.1
chr3_-_186288097 0.23 ENST00000446782.1
TBCC domain containing 1
chr9_-_5833027 0.23 ENST00000339450.5
endoplasmic reticulum metallopeptidase 1
chr8_-_38008783 0.23 ENST00000276449.4
steroidogenic acute regulatory protein
chr16_+_28648975 0.23 ENST00000529716.1
nuclear pore complex interacting protein family, member B8
chr16_+_28763108 0.23 ENST00000357796.3
ENST00000550983.1
nuclear pore complex interacting protein family, member B9
chr20_-_29978383 0.22 ENST00000339144.3
ENST00000376321.3
defensin, beta 119
chr7_-_44887620 0.22 ENST00000349299.3
ENST00000521529.1
ENST00000308153.4
ENST00000350771.3
ENST00000222690.6
ENST00000381124.5
ENST00000437072.1
ENST00000446531.1
H2A histone family, member V
chr1_-_170043709 0.22 ENST00000367767.1
ENST00000361580.2
ENST00000538366.1
kinesin-associated protein 3
chr4_-_100140331 0.22 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
alcohol dehydrogenase 6 (class V)
chr12_-_91574142 0.21 ENST00000547937.1
decorin
chr1_-_190446759 0.21 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr8_-_143859197 0.21 ENST00000395192.2
Ly6/neurotoxin 1
chr12_+_9980069 0.21 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
killer cell lectin-like receptor subfamily F, member 1
chr11_-_124981475 0.21 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
transmembrane protein 218
chr17_-_4938712 0.21 ENST00000254853.5
ENST00000424747.1
solute carrier family 52 (riboflavin transporter), member 1
chr4_+_41540160 0.20 ENST00000503057.1
ENST00000511496.1
LIM and calponin homology domains 1
chr11_+_122753391 0.19 ENST00000307257.6
ENST00000227349.2
chromosome 11 open reading frame 63
chr1_+_233765353 0.19 ENST00000366620.1
potassium channel, subfamily K, member 1
chr9_-_99540328 0.19 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
zinc finger protein 510
chr8_+_98900132 0.19 ENST00000520016.1
matrilin 2
chrX_+_105412290 0.18 ENST00000357175.2
ENST00000337685.2
melanoma associated antigen (mutated) 1-like 1
chr5_-_58571935 0.18 ENST00000503258.1
phosphodiesterase 4D, cAMP-specific
chr6_+_30585486 0.18 ENST00000259873.4
ENST00000506373.2
mitochondrial ribosomal protein S18B
chr9_+_71986182 0.18 ENST00000303068.7
family with sequence similarity 189, member A2
chr1_-_13390765 0.18 ENST00000357367.2
PRAME family member 8
chr5_+_81575281 0.18 ENST00000380167.4
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr17_-_42100474 0.17 ENST00000585950.1
ENST00000592127.1
ENST00000589334.1
transmembrane protein 101
chr7_+_138145076 0.17 ENST00000343526.4
tripartite motif containing 24
chr8_+_24151553 0.17 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM metallopeptidase domain 28
chrX_+_130192318 0.17 ENST00000370922.1
Rho GTPase activating protein 36
chr12_+_10365404 0.16 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABA(A) receptor-associated protein like 1
chr9_+_71944241 0.16 ENST00000257515.8
family with sequence similarity 189, member A2
chr6_+_6588316 0.16 ENST00000379953.2
lymphocyte antigen 86
chr3_+_148508845 0.16 ENST00000491148.1
carboxypeptidase B1 (tissue)
chr1_-_85870177 0.16 ENST00000542148.1
dimethylarginine dimethylaminohydrolase 1
chr8_-_101571933 0.16 ENST00000520311.1
ankyrin repeat domain 46
chr11_-_327537 0.16 ENST00000602735.1
interferon induced transmembrane protein 3
chr2_-_179343226 0.15 ENST00000434643.2
FK506 binding protein 7
chr16_-_4817129 0.15 ENST00000545009.1
ENST00000219478.6
zinc finger protein 500
chr3_+_40518599 0.15 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
zinc finger protein 619
chr1_+_117544366 0.15 ENST00000256652.4
ENST00000369470.1
CD101 molecule
chr3_-_58523010 0.15 ENST00000459701.2
ENST00000302819.5
acyl-CoA oxidase 2, branched chain
chr15_-_41166414 0.15 ENST00000220507.4
ras homolog family member V
chr2_+_44001172 0.15 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
dynein, cytoplasmic 2, light intermediate chain 1
chr7_-_140482926 0.15 ENST00000496384.2
v-raf murine sarcoma viral oncogene homolog B
chr5_+_178977546 0.15 ENST00000319449.4
ENST00000377001.2
RUN and FYVE domain containing 1
chr13_+_108921977 0.14 ENST00000430559.1
ENST00000375887.4
tumor necrosis factor (ligand) superfamily, member 13b
chr17_-_39324424 0.14 ENST00000391356.2
keratin associated protein 4-3
chr15_+_77712993 0.14 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
high mobility group 20A
chr9_+_75766763 0.14 ENST00000456643.1
ENST00000415424.1
annexin A1
chr1_-_19615744 0.14 ENST00000361640.4
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
chr4_-_120243545 0.14 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr2_-_197226875 0.13 ENST00000409111.1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr15_+_64680003 0.13 ENST00000261884.3
thyroid hormone receptor interactor 4
chr15_-_65903407 0.13 ENST00000395644.4
ENST00000567744.1
ENST00000568573.1
ENST00000562830.1
ENST00000569491.1
ENST00000561769.1
von Willebrand factor A domain containing 9
chr6_+_110501621 0.13 ENST00000368930.1
ENST00000307731.1
cell division cycle 40
chr2_+_120687335 0.13 ENST00000544261.1
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chrX_+_18443703 0.13 ENST00000379996.3
cyclin-dependent kinase-like 5
chr15_-_78913521 0.13 ENST00000326828.5
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr3_+_39424828 0.12 ENST00000273158.4
ENST00000431510.1
solute carrier family 25, member 38
chr4_-_68411275 0.12 ENST00000273853.6
centromere protein C
chr8_-_57123815 0.12 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
pleiomorphic adenoma gene 1
chr16_+_22524844 0.12 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
nuclear pore complex interacting protein family, member B5
chr14_-_90420862 0.12 ENST00000556005.1
ENST00000555872.1
EF-hand calcium binding domain 11
chr19_+_15852203 0.12 ENST00000305892.1
olfactory receptor, family 10, subfamily H, member 3
chr3_+_32993065 0.12 ENST00000330953.5
chemokine (C-C motif) receptor 4
chr20_+_15177480 0.12 ENST00000402914.1
MACRO domain containing 2
chr10_-_27529486 0.11 ENST00000375888.1
acyl-CoA binding domain containing 5
chr5_+_55147205 0.11 ENST00000396836.2
ENST00000396834.1
ENST00000447346.2
ENST00000359040.5
interleukin 31 receptor A
chrX_+_36053908 0.11 ENST00000378660.2
calponin homology domain containing 2
chr4_+_113568207 0.11 ENST00000511529.1
La ribonucleoprotein domain family, member 7
chr9_-_116065551 0.11 ENST00000297894.5
ring finger protein 183
chr2_+_234826016 0.11 ENST00000324695.4
ENST00000433712.2
transient receptor potential cation channel, subfamily M, member 8
chr6_+_110501344 0.11 ENST00000368932.1
cell division cycle 40
chr13_+_103459704 0.11 ENST00000602836.1
BIVM-ERCC5 readthrough
chr9_-_28670283 0.11 ENST00000379992.2
leucine rich repeat and Ig domain containing 2
chr12_+_59989918 0.11 ENST00000547379.1
ENST00000549465.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr17_+_7239821 0.11 ENST00000158762.3
ENST00000570457.2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr22_+_45725524 0.11 ENST00000405548.3
family with sequence similarity 118, member A
chr6_-_9933500 0.11 ENST00000492169.1
orofacial cleft 1 candidate 1
chr16_+_11038345 0.10 ENST00000409790.1
C-type lectin domain family 16, member A
chr14_+_55493920 0.10 ENST00000395472.2
ENST00000555846.1
suppressor of cytokine signaling 4
chr10_+_51187938 0.10 ENST00000311663.5
family with sequence similarity 21, member D
chr1_-_92952433 0.10 ENST00000294702.5
growth factor independent 1 transcription repressor
chr2_+_32502952 0.10 ENST00000238831.4
Yip1 domain family, member 4
chr15_+_75970672 0.10 ENST00000435356.1
Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr3_+_195413160 0.10 ENST00000599448.1
long intergenic non-protein coding RNA 969
chr3_+_38080691 0.09 ENST00000308059.6
ENST00000346219.3
ENST00000452631.2
deleted in lung and esophageal cancer 1
chr11_-_102714534 0.09 ENST00000299855.5
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chrX_-_9734004 0.09 ENST00000467482.1
ENST00000380929.2
G protein-coupled receptor 143
chr1_-_39347255 0.09 ENST00000454994.2
ENST00000357771.3
gap junction protein, alpha 9, 59kDa
chr19_-_37697976 0.09 ENST00000588873.1
Uncharacterized protein; Zinc finger protein 585B

Network of associatons between targets according to the STRING database.

First level regulatory network of EMX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 2.9 GO:0036159 inner dynein arm assembly(GO:0036159)
0.2 0.8 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 1.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.3 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.4 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 1.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.4 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.4 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.8 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 1.4 GO:0003351 epithelial cilium movement(GO:0003351)
0.1 0.2 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 1.5 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.3 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 1.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 4.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.2 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.0 0.2 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.4 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.8 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.5 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.0 0.5 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.0 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.7 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0006067 ethanol metabolic process(GO:0006067)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:0071231 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) cellular response to folic acid(GO:0071231)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.7 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 1.5 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.5 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 2.9 GO:0007586 digestion(GO:0007586)
0.0 1.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 1.4 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527) negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 2.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.2 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 4.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.0 1.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.6 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.4 GO:0030990 intraciliary transport particle(GO:0030990)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 5.5 GO:0005929 cilium(GO:0005929)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.3 1.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 0.8 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 0.7 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 1.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.2 2.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.3 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.5 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 1.4 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.4 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 1.4 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 1.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.8 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.5 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.8 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.4 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 5.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 4.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 0.8 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones