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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for EOMES

Z-value: 0.68

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Transcription factors associated with EOMES

Gene Symbol Gene ID Gene Info
EOMES
ENSG00000163508.8 eomesodermin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EOMEShg19_v2_chr3_-_27763803_277638220.067.6e-01Click!

Activity profile of EOMES motif

Sorted Z-values of EOMES motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_116937636 1.85 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A
radial spoke head 4 homolog A (Chlamydomonas)
chr22_-_50970506 1.38 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr14_+_96858433 1.28 ENST00000267584.4
AK7
adenylate kinase 7
chr7_+_6793740 1.17 ENST00000403107.1
ENST00000404077.1
ENST00000435395.1
ENST00000418406.1
RSPH10B2
radial spoke head 10 homolog B2 (Chlamydomonas)
chr7_-_6010263 1.14 ENST00000455618.2
ENST00000405415.1
ENST00000404406.1
ENST00000542644.1
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chr15_-_56757329 1.12 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr19_-_55677920 1.10 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3
dynein, axonemal, assembly factor 3
chr11_-_8615507 0.97 ENST00000431279.2
ENST00000418597.1
STK33
serine/threonine kinase 33
chr7_+_94285637 0.92 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr6_+_163148973 0.89 ENST00000366888.2
PACRG
PARK2 co-regulated
chr16_-_66959429 0.88 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr14_-_55658252 0.87 ENST00000395425.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr17_-_19266045 0.83 ENST00000395616.3
B9D1
B9 protein domain 1
chr3_-_113775328 0.80 ENST00000483766.1
ENST00000545063.1
ENST00000491000.1
ENST00000295878.3
KIAA1407
KIAA1407
chr7_+_89874524 0.71 ENST00000497910.1
C7orf63
chromosome 7 open reading frame 63
chr8_+_81397876 0.71 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chrY_+_15016725 0.68 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr7_+_89874483 0.67 ENST00000389297.4
ENST00000316089.8
C7orf63
chromosome 7 open reading frame 63
chr5_+_75699149 0.67 ENST00000379730.3
IQGAP2
IQ motif containing GTPase activating protein 2
chr14_-_55658323 0.67 ENST00000554067.1
ENST00000247191.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr17_-_33775760 0.66 ENST00000534689.1
ENST00000532210.1
ENST00000526861.1
ENST00000531588.1
ENST00000285013.6
SLFN13
schlafen family member 13
chr3_-_137834436 0.65 ENST00000327532.2
ENST00000467030.1
DZIP1L
DAZ interacting zinc finger protein 1-like
chr22_-_37545972 0.65 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr11_-_8615720 0.60 ENST00000358872.3
ENST00000454443.2
STK33
serine/threonine kinase 33
chr17_-_19265982 0.59 ENST00000268841.6
ENST00000261499.4
ENST00000575478.1
B9D1
B9 protein domain 1
chr6_-_139613269 0.59 ENST00000358430.3
TXLNB
taxilin beta
chr17_-_74533734 0.58 ENST00000589342.1
CYGB
cytoglobin
chr3_-_127842612 0.58 ENST00000417360.1
ENST00000322623.5
RUVBL1
RuvB-like AAA ATPase 1
chr11_-_8615488 0.57 ENST00000315204.1
ENST00000396672.1
ENST00000396673.1
STK33
serine/threonine kinase 33
chr1_-_207095324 0.55 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr16_-_2031464 0.52 ENST00000356120.4
ENST00000354249.4
NOXO1
NADPH oxidase organizer 1
chr2_-_152118352 0.50 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr11_-_70672645 0.50 ENST00000423696.2
SHANK2
SH3 and multiple ankyrin repeat domains 2
chrX_+_51149767 0.50 ENST00000342995.2
CXorf67
chromosome X open reading frame 67
chr1_-_203144941 0.49 ENST00000255416.4
MYBPH
myosin binding protein H
chr1_+_213031570 0.49 ENST00000366971.4
FLVCR1
feline leukemia virus subgroup C cellular receptor 1
chr4_-_16085314 0.48 ENST00000510224.1
PROM1
prominin 1
chr1_-_115632035 0.48 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
TSPAN2
tetraspanin 2
chr4_-_16085340 0.47 ENST00000508167.1
PROM1
prominin 1
chrY_+_15016013 0.45 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr2_-_229046330 0.45 ENST00000344657.5
SPHKAP
SPHK1 interactor, AKAP domain containing
chr2_-_229046361 0.45 ENST00000392056.3
SPHKAP
SPHK1 interactor, AKAP domain containing
chr14_-_21979428 0.44 ENST00000538267.1
ENST00000298717.4
METTL3
methyltransferase like 3
chr1_-_167906277 0.43 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr1_+_65775204 0.43 ENST00000371069.4
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr7_+_102105370 0.42 ENST00000292616.5
LRWD1
leucine-rich repeats and WD repeat domain containing 1
chr2_-_101767715 0.42 ENST00000376840.4
ENST00000409318.1
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr14_+_56585048 0.42 ENST00000267460.4
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr17_-_42907564 0.41 ENST00000592524.1
GJC1
gap junction protein, gamma 1, 45kDa
chr11_-_105892937 0.40 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
MSANTD4
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr17_-_19265855 0.40 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9D1
B9 protein domain 1
chr2_+_230787201 0.38 ENST00000283946.3
FBXO36
F-box protein 36
chr7_-_37024665 0.38 ENST00000396040.2
ELMO1
engulfment and cell motility 1
chr9_+_100069933 0.37 ENST00000529487.1
CCDC180
coiled-coil domain containing 180
chr2_+_230787213 0.37 ENST00000409992.1
FBXO36
F-box protein 36
chr14_-_64108125 0.37 ENST00000267522.3
WDR89
WD repeat domain 89
chr3_+_101504200 0.36 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr5_+_156693159 0.36 ENST00000347377.6
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr8_+_99076750 0.36 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr1_-_207095212 0.34 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr4_+_186347388 0.34 ENST00000511138.1
ENST00000511581.1
C4orf47
chromosome 4 open reading frame 47
chr8_-_79717750 0.34 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr8_+_99076509 0.33 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr8_+_16884740 0.33 ENST00000318063.5
MICU3
mitochondrial calcium uptake family, member 3
chr19_+_49496705 0.32 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr16_+_86544113 0.32 ENST00000262426.4
FOXF1
forkhead box F1
chr5_-_40755987 0.31 ENST00000337702.4
TTC33
tetratricopeptide repeat domain 33
chr19_+_38085731 0.31 ENST00000589117.1
ZNF540
zinc finger protein 540
chr3_+_111805182 0.30 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
C3orf52
chromosome 3 open reading frame 52
chr7_-_138482933 0.30 ENST00000310018.2
ATP6V0A4
ATPase, H+ transporting, lysosomal V0 subunit a4
chr17_+_67498538 0.30 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr21_+_33671264 0.30 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr12_+_31812121 0.30 ENST00000395763.3
METTL20
methyltransferase like 20
chr16_+_66914264 0.29 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr4_+_169418255 0.29 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr6_+_154360616 0.29 ENST00000229768.5
ENST00000419506.2
ENST00000524163.1
ENST00000414028.2
ENST00000435918.2
ENST00000337049.4
OPRM1
opioid receptor, mu 1
chr1_+_215256467 0.29 ENST00000391894.2
ENST00000444842.2
KCNK2
potassium channel, subfamily K, member 2
chr7_+_87505544 0.29 ENST00000265728.1
DBF4
DBF4 homolog (S. cerevisiae)
chr8_-_9760839 0.29 ENST00000519461.1
ENST00000517675.1
LINC00599
long intergenic non-protein coding RNA 599
chr5_+_156693091 0.29 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr11_+_65479462 0.28 ENST00000377046.3
ENST00000352980.4
ENST00000341318.4
KAT5
K(lysine) acetyltransferase 5
chr17_-_74722536 0.28 ENST00000585429.1
JMJD6
jumonji domain containing 6
chr1_-_43751230 0.28 ENST00000523677.1
C1orf210
chromosome 1 open reading frame 210
chr4_+_169418195 0.28 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr8_-_124408652 0.27 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr11_-_8615687 0.27 ENST00000534493.1
ENST00000422559.2
STK33
serine/threonine kinase 33
chr19_+_49496782 0.27 ENST00000601968.1
ENST00000596837.1
RUVBL2
RuvB-like AAA ATPase 2
chr5_-_94620239 0.27 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr17_+_9066252 0.26 ENST00000436734.1
NTN1
netrin 1
chr17_-_60005365 0.26 ENST00000444766.3
INTS2
integrator complex subunit 2
chr19_+_15121532 0.26 ENST00000292574.3
CCDC105
coiled-coil domain containing 105
chr8_-_27469196 0.26 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr7_-_138482849 0.26 ENST00000353492.4
ATP6V0A4
ATPase, H+ transporting, lysosomal V0 subunit a4
chr7_-_93520191 0.26 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr1_+_60280458 0.25 ENST00000455990.1
ENST00000371208.3
HOOK1
hook microtubule-tethering protein 1
chr8_+_96037205 0.25 ENST00000396124.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr1_+_25598989 0.25 ENST00000454452.2
RHD
Rh blood group, D antigen
chr1_-_167906020 0.24 ENST00000458574.1
MPC2
mitochondrial pyruvate carrier 2
chr10_-_61900762 0.24 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_-_76862117 0.23 ENST00000507956.1
ENST00000507187.2
ENST00000399497.3
ENST00000286733.4
NAAA
N-acylethanolamine acid amidase
chr14_-_51135036 0.23 ENST00000324679.4
SAV1
salvador homolog 1 (Drosophila)
chr11_+_73498898 0.23 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48
mitochondrial ribosomal protein L48
chr11_+_64808675 0.23 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr4_-_151936865 0.23 ENST00000535741.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr4_+_4291924 0.22 ENST00000355834.3
ENST00000337872.4
ENST00000538529.1
ENST00000502918.1
ZBTB49
zinc finger and BTB domain containing 49
chr18_-_19284724 0.22 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr11_+_65479702 0.22 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
KAT5
K(lysine) acetyltransferase 5
chr14_+_96858454 0.22 ENST00000555570.1
AK7
adenylate kinase 7
chr1_+_246729724 0.22 ENST00000366513.4
ENST00000366512.3
CNST
consortin, connexin sorting protein
chr7_-_100026280 0.22 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr1_+_150229554 0.22 ENST00000369111.4
CA14
carbonic anhydrase XIV
chr17_+_58755184 0.22 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr2_-_148778323 0.21 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr21_-_47352477 0.21 ENST00000593412.1
PRED62
Uncharacterized protein
chr7_-_91875358 0.21 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1
KRIT1, ankyrin repeat containing
chr21_+_34619079 0.21 ENST00000433395.2
AP000295.9
AP000295.9
chr12_+_93965609 0.21 ENST00000549887.1
ENST00000551556.1
SOCS2
suppressor of cytokine signaling 2
chr19_-_40791211 0.21 ENST00000579047.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr2_-_161350305 0.21 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr12_+_54378923 0.21 ENST00000303460.4
HOXC10
homeobox C10
chr19_+_55795493 0.21 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr1_-_213031418 0.21 ENST00000356684.3
ENST00000426161.1
ENST00000424044.1
FLVCR1-AS1
FLVCR1 antisense RNA 1 (head to head)
chr4_-_2420335 0.21 ENST00000503000.1
ZFYVE28
zinc finger, FYVE domain containing 28
chr17_-_62493131 0.21 ENST00000539111.2
POLG2
polymerase (DNA directed), gamma 2, accessory subunit
chr3_+_125687987 0.21 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
ROPN1B
rhophilin associated tail protein 1B
chr7_+_106685079 0.21 ENST00000265717.4
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr19_-_36499521 0.21 ENST00000397428.3
ENST00000503121.1
ENST00000340477.5
ENST00000324444.3
ENST00000490730.1
SYNE4
spectrin repeat containing, nuclear envelope family member 4
chr1_-_146644036 0.20 ENST00000425272.2
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr8_+_67687413 0.20 ENST00000521960.1
ENST00000522398.1
ENST00000522629.1
ENST00000520976.1
ENST00000396596.1
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr10_+_26505594 0.20 ENST00000259271.3
GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr13_+_73302047 0.20 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
BORA
bora, aurora kinase A activator
chr19_+_7599597 0.20 ENST00000414982.3
ENST00000450331.3
PNPLA6
patatin-like phospholipase domain containing 6
chr19_-_14016877 0.20 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
C19orf57
chromosome 19 open reading frame 57
chr7_+_16793160 0.20 ENST00000262067.4
TSPAN13
tetraspanin 13
chr1_-_226595741 0.20 ENST00000366794.5
ENST00000366792.1
ENST00000366791.5
PARP1
poly (ADP-ribose) polymerase 1
chr4_-_4291761 0.19 ENST00000513174.1
LYAR
Ly1 antibody reactive
chr5_+_149109825 0.19 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr14_+_54863739 0.19 ENST00000541304.1
CDKN3
cyclin-dependent kinase inhibitor 3
chrX_-_54070607 0.19 ENST00000338154.6
ENST00000338946.6
PHF8
PHD finger protein 8
chr17_-_38256973 0.19 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr7_+_65540853 0.19 ENST00000380839.4
ENST00000395332.3
ENST00000362000.5
ENST00000395331.3
ASL
argininosuccinate lyase
chr12_-_58131931 0.19 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr9_-_136223324 0.19 ENST00000371974.3
SURF1
surfeit 1
chr7_-_93520259 0.19 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr11_-_3663502 0.18 ENST00000359918.4
ART5
ADP-ribosyltransferase 5
chr22_+_45680822 0.18 ENST00000216211.4
ENST00000396082.2
UPK3A
uroplakin 3A
chr17_+_68100989 0.18 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_-_146644122 0.18 ENST00000254101.3
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr18_+_2655849 0.18 ENST00000261598.8
SMCHD1
structural maintenance of chromosomes flexible hinge domain containing 1
chr3_-_53381539 0.18 ENST00000606822.1
ENST00000294241.6
ENST00000607628.1
DCP1A
decapping mRNA 1A
chr17_+_37784749 0.18 ENST00000394265.1
ENST00000394267.2
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr22_+_40742512 0.18 ENST00000454266.2
ENST00000342312.6
ADSL
adenylosuccinate lyase
chr7_+_130131907 0.18 ENST00000223215.4
ENST00000437945.1
MEST
mesoderm specific transcript
chr18_+_48556470 0.18 ENST00000589076.1
ENST00000590061.1
ENST00000591914.1
ENST00000342988.3
SMAD4
SMAD family member 4
chr3_-_43147431 0.18 ENST00000441964.1
POMGNT2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr11_+_67183557 0.18 ENST00000445895.2
CARNS1
carnosine synthase 1
chr1_+_15573757 0.18 ENST00000358897.4
ENST00000417793.1
ENST00000375999.3
ENST00000433640.2
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr17_-_57184260 0.18 ENST00000376149.3
ENST00000393066.3
TRIM37
tripartite motif containing 37
chr1_+_218458625 0.18 ENST00000366932.3
RRP15
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr1_-_205744205 0.18 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr17_+_9548845 0.18 ENST00000570475.1
ENST00000285199.7
USP43
ubiquitin specific peptidase 43
chr17_+_48912744 0.18 ENST00000311378.4
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chrX_-_134478012 0.17 ENST00000370766.3
ZNF75D
zinc finger protein 75D
chr3_-_52868931 0.17 ENST00000486659.1
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr6_-_131949200 0.17 ENST00000539158.1
ENST00000368058.1
MED23
mediator complex subunit 23
chr10_-_13342097 0.17 ENST00000263038.4
PHYH
phytanoyl-CoA 2-hydroxylase
chrX_+_37430822 0.17 ENST00000378621.3
ENST00000378619.3
LANCL3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr14_+_76127529 0.17 ENST00000556977.1
ENST00000557636.1
ENST00000286650.5
ENST00000298832.9
TTLL5
tubulin tyrosine ligase-like family, member 5
chr18_+_43753974 0.17 ENST00000282059.6
ENST00000321319.6
C18orf25
chromosome 18 open reading frame 25
chr4_-_140222358 0.17 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr6_+_79577189 0.17 ENST00000369940.2
IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr20_-_17539456 0.17 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr1_+_19578033 0.17 ENST00000330263.4
MRTO4
mRNA turnover 4 homolog (S. cerevisiae)
chr13_+_103459704 0.17 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr12_-_101604185 0.17 ENST00000536262.2
SLC5A8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr2_-_197791441 0.17 ENST00000409475.1
ENST00000354764.4
ENST00000374738.3
PGAP1
post-GPI attachment to proteins 1
chr19_-_38085633 0.17 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
ZNF571
zinc finger protein 571
chr2_+_45878790 0.17 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr13_+_113633620 0.16 ENST00000421756.1
ENST00000375601.3
MCF2L
MCF.2 cell line derived transforming sequence-like
chr1_+_26438289 0.16 ENST00000374271.4
ENST00000374269.1
PDIK1L
PDLIM1 interacting kinase 1 like
chr1_-_36851475 0.16 ENST00000373129.3
STK40
serine/threonine kinase 40
chr16_-_75569068 0.16 ENST00000336257.3
ENST00000565039.1
CHST5
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
chr1_+_162531294 0.16 ENST00000367926.4
ENST00000271469.3
UAP1
UDP-N-acteylglucosamine pyrophosphorylase 1
chr2_-_97523721 0.16 ENST00000393537.4
ANKRD39
ankyrin repeat domain 39
chr15_-_43622736 0.16 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
LCMT2
leucine carboxyl methyltransferase 2
chr6_+_168227611 0.16 ENST00000344191.4
ENST00000351017.4
ENST00000392108.3
ENST00000366806.2
ENST00000392112.1
ENST00000400824.4
ENST00000447894.2
ENST00000400822.3
MLLT4
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr1_-_109203685 0.16 ENST00000402983.1
ENST00000420055.1
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr7_+_150020329 0.16 ENST00000323078.7
LRRC61
leucine rich repeat containing 61
chr11_+_64808368 0.16 ENST00000531072.1
ENST00000398846.1
SAC3D1
SAC3 domain containing 1
chr1_-_94312706 0.16 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chr1_+_162760513 0.16 ENST00000367915.1
ENST00000367917.3
ENST00000254521.3
ENST00000367913.1
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr10_-_58120996 0.15 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
ZWINT
ZW10 interacting kinetochore protein
chrX_-_63005405 0.15 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr7_+_65540780 0.15 ENST00000304874.9
ASL
argininosuccinate lyase
chr18_-_268019 0.15 ENST00000261600.6
THOC1
THO complex 1
chr14_+_21510385 0.15 ENST00000298690.4
RNASE7
ribonuclease, RNase A family, 7
chr2_-_148778258 0.15 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4
origin recognition complex, subunit 4
chr1_-_222721434 0.15 ENST00000343410.6
HHIPL2
HHIP-like 2
chr11_-_64052111 0.15 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BAD
BCL2-associated agonist of cell death
chr3_-_43147549 0.15 ENST00000344697.2
POMGNT2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)

Network of associatons between targets according to the STRING database.

First level regulatory network of EOMES

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.2 0.9 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.2 0.9 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.7 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.6 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.3 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.1 0.3 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) right lung development(GO:0060458)
0.1 0.4 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.6 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.1 0.3 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.6 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.4 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.3 GO:0071484 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.1 0.5 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 0.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.3 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.1 0.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.3 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.1 0.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.2 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188) histone H3-K27 demethylation(GO:0071557)
0.1 0.3 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.2 GO:1904253 circadian temperature homeostasis(GO:0060086) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.2 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.1 0.2 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 1.1 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.2 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.4 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.2 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.1 0.4 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.1 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0 0.1 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 3.1 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0072192 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) deltoid tuberosity development(GO:0035993) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.0 0.3 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.5 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:0045799 mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.1 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.5 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:1904172 NAD transport(GO:0043132) regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.0 0.5 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.2 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.5 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.3 GO:0015840 urea transport(GO:0015840)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0097195 pilomotor reflex(GO:0097195)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.3 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 1.5 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 1.8 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.1 GO:0071315 cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
0.0 0.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.5 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.2 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.1 GO:0072107 postganglionic parasympathetic fiber development(GO:0021784) regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.0 0.1 GO:0032308 regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
0.0 0.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.6 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.2 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.0 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.5 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.5 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 2.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.3 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.1 GO:1901910 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.0 GO:0090166 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) Golgi disassembly(GO:0090166)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0001534 radial spoke(GO:0001534)
0.1 0.4 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 1.1 GO:0097255 R2TP complex(GO:0097255)
0.1 0.4 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 1.8 GO:0036038 MKS complex(GO:0036038)
0.1 1.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.2 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 0.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.3 GO:0044305 calyx of Held(GO:0044305)
0.1 0.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0001740 Barr body(GO:0001740)
0.0 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.5 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.7 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.0 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.3 GO:0044453 nuclear membrane part(GO:0044453)
0.0 0.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.2 1.8 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 0.6 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 1.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.6 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.4 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.7 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.7 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.3 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.4 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.2 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.3 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.1 0.2 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.2 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.2 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.9 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.0 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 1.4 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.9 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.0 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0043199 sulfate binding(GO:0043199)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0052847 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.0 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID MYC PATHWAY C-MYC pathway
0.0 1.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.1 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA