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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ESR1

Z-value: 1.09

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Transcription factors associated with ESR1

Gene Symbol Gene ID Gene Info
ENSG00000091831.17 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESR1hg19_v2_chr6_+_152130240_152130274-0.212.6e-01Click!

Activity profile of ESR1 motif

Sorted Z-values of ESR1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_46089718 6.59 ENST00000421127.2
ENST00000343901.2
ENST00000528266.1
coiled-coil domain containing 17
chr7_-_99569468 5.59 ENST00000419575.1
alpha-2-glycoprotein 1, zinc-binding
chr1_-_46089639 5.35 ENST00000445048.2
coiled-coil domain containing 17
chr15_+_81426588 5.26 ENST00000286732.4
chromosome 15 open reading frame 26
chr16_-_67427389 5.04 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
tubulin polymerization-promoting protein family member 3
chr2_+_120187465 4.36 ENST00000409826.1
ENST00000417645.1
transmembrane protein 37
chr16_-_28621353 4.30 ENST00000567512.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_+_47264711 4.15 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
cytochrome P450, family 4, subfamily B, polypeptide 1
chr14_-_107078851 4.02 ENST00000390628.2
immunoglobulin heavy variable 1-58
chr16_-_21289627 3.85 ENST00000396023.2
ENST00000415987.2
crystallin, mu
chr1_+_245133656 3.85 ENST00000366521.3
EF-hand calcium binding domain 2
chr8_+_120885949 3.57 ENST00000523492.1
ENST00000286234.5
DEP domain containing MTOR-interacting protein
chr13_-_36705425 3.46 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
doublecortin-like kinase 1
chr14_-_106642049 3.21 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr1_-_36915880 3.18 ENST00000445843.3
organic solute carrier partner 1
chr11_-_111170526 3.11 ENST00000355430.4
colorectal cancer associated 1
chr3_-_52488048 3.10 ENST00000232975.3
troponin C type 1 (slow)
chr1_+_217804661 3.07 ENST00000366933.4
spermatogenesis associated 17
chr9_-_130637244 2.98 ENST00000373156.1
adenylate kinase 1
chr12_+_102091400 2.96 ENST00000229266.3
ENST00000549872.1
choline phosphotransferase 1
chr14_-_65438865 2.91 ENST00000267512.5
RAB15, member RAS oncogene family
chr11_+_27062272 2.81 ENST00000529202.1
ENST00000533566.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_+_118148556 2.81 ENST00000369448.3
family with sequence similarity 46, member C
chr15_+_50474385 2.79 ENST00000267842.5
solute carrier family 27 (fatty acid transporter), member 2
chr1_-_223853348 2.78 ENST00000366872.5
calpain 8
chr15_+_50474412 2.73 ENST00000380902.4
solute carrier family 27 (fatty acid transporter), member 2
chr1_-_36916066 2.68 ENST00000315643.9
organic solute carrier partner 1
chr10_+_114135952 2.66 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
acyl-CoA synthetase long-chain family member 5
chr6_-_90121938 2.60 ENST00000369415.4
Ras-related GTP binding D
chr11_+_27062502 2.57 ENST00000263182.3
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr19_-_18717627 2.57 ENST00000392386.3
cytokine receptor-like factor 1
chr2_+_98703643 2.56 ENST00000477737.1
von Willebrand factor A domain containing 3B
chr11_+_1891380 2.43 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
lymphocyte-specific protein 1
chr11_+_827553 2.36 ENST00000528542.2
ENST00000450448.1
EF-hand calcium binding domain 4A
chrX_+_16964794 2.28 ENST00000357277.3
RALBP1 associated Eps domain containing 2
chr1_-_36916011 2.26 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
organic solute carrier partner 1
chr16_-_28621312 2.26 ENST00000314752.7
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr16_+_71560154 2.25 ENST00000539698.3
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr1_+_67218124 2.24 ENST00000282670.2
Tctex1 domain containing 1
chr3_-_46506358 2.21 ENST00000417439.1
ENST00000431944.1
lactotransferrin
chr5_-_16509101 2.16 ENST00000399793.2
family with sequence similarity 134, member B
chr15_+_78556809 2.13 ENST00000343789.3
ENST00000394852.3
DnaJ (Hsp40) homolog, subfamily A, member 4
chr16_+_30210552 2.13 ENST00000338971.5
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr2_-_38303218 2.12 ENST00000407341.1
ENST00000260630.3
cytochrome P450, family 1, subfamily B, polypeptide 1
chr16_+_29471210 2.11 ENST00000360423.7
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr11_-_63376013 2.10 ENST00000540943.1
phospholipase A2, group XVI
chr16_+_616995 2.08 ENST00000293874.2
ENST00000409527.2
ENST00000424439.2
ENST00000540585.1
phosphatidylinositol glycan anchor biosynthesis, class Q
NHL repeat containing 4
chr21_-_40817645 2.07 ENST00000438404.1
ENST00000358268.2
ENST00000411566.1
ENST00000451131.1
ENST00000418018.1
ENST00000415863.1
ENST00000426783.1
ENST00000288350.3
ENST00000485895.2
ENST00000448288.2
ENST00000456017.1
ENST00000434281.1
Leber congenital amaurosis 5-like
chr6_+_24495067 2.06 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
aldehyde dehydrogenase 5 family, member A1
chr22_+_39853258 2.06 ENST00000341184.6
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr17_-_40346477 2.06 ENST00000593209.1
ENST00000587427.1
ENST00000588352.1
ENST00000414034.3
ENST00000590249.1
GH3 domain containing
chr2_-_28113965 2.00 ENST00000302188.3
ribokinase
chr14_+_75536335 1.98 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
zinc finger, C2HC-type containing 1C
chr3_+_58223228 1.96 ENST00000478253.1
ENST00000295962.4
abhydrolase domain containing 6
chr2_+_98330009 1.96 ENST00000264972.5
zeta-chain (TCR) associated protein kinase 70kDa
chr10_+_115438920 1.94 ENST00000429617.1
ENST00000369331.4
caspase 7, apoptosis-related cysteine peptidase
chr14_+_75536280 1.93 ENST00000238686.8
zinc finger, C2HC-type containing 1C
chr22_+_39745930 1.93 ENST00000318801.4
ENST00000216155.7
ENST00000406293.3
ENST00000328933.5
synaptogyrin 1
chr3_-_122512619 1.91 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr19_-_55972936 1.87 ENST00000425675.2
ENST00000589080.1
ENST00000085068.3
isochorismatase domain containing 2
chr1_+_245133278 1.86 ENST00000366522.2
EF-hand calcium binding domain 2
chr20_+_48429233 1.85 ENST00000417961.1
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr19_-_6433765 1.77 ENST00000321510.6
solute carrier family 25, member 41
chrX_+_16964985 1.76 ENST00000303843.7
RALBP1 associated Eps domain containing 2
chr18_-_45935663 1.75 ENST00000589194.1
ENST00000591279.1
ENST00000590855.1
ENST00000587107.1
ENST00000588970.1
ENST00000586525.1
ENST00000592387.1
ENST00000590800.1
zinc finger and BTB domain containing 7C
chr12_-_63328817 1.75 ENST00000228705.6
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr11_-_86383370 1.75 ENST00000526834.1
ENST00000359636.2
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr3_-_93781750 1.74 ENST00000314636.2
dihydrofolate reductase-like 1
chr19_-_6720686 1.70 ENST00000245907.6
complement component 3
chr22_+_23046750 1.70 ENST00000390307.2
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr1_+_38259540 1.69 ENST00000397631.3
mannosidase, endo-alpha-like
chr9_+_976964 1.69 ENST00000190165.2
doublesex and mab-3 related transcription factor 3
chr12_-_42877726 1.67 ENST00000548696.1
prickle homolog 1 (Drosophila)
chr12_-_50294033 1.67 ENST00000552669.1
Fas apoptotic inhibitory molecule 2
chr16_-_28621298 1.64 ENST00000566189.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr7_+_94139105 1.64 ENST00000297273.4
CAS1 domain containing 1
chr20_+_48429356 1.62 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr12_-_50297638 1.61 ENST00000320634.3
Fas apoptotic inhibitory molecule 2
chr16_+_2079637 1.59 ENST00000561844.1
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr1_+_38259459 1.59 ENST00000373045.6
mannosidase, endo-alpha-like
chr3_-_183273477 1.58 ENST00000341319.3
kelch-like family member 6
chr2_-_220110111 1.50 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
galactosidase, beta 1-like
chr11_+_67777751 1.50 ENST00000316367.6
ENST00000007633.8
ENST00000342456.6
aldehyde dehydrogenase 3 family, member B1
chr16_-_28608424 1.46 ENST00000335715.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr8_+_144640477 1.46 ENST00000262580.4
gasdermin D
chr4_+_186347388 1.45 ENST00000511138.1
ENST00000511581.1
chromosome 4 open reading frame 47
chr11_-_86383650 1.44 ENST00000526944.1
ENST00000530335.1
ENST00000543262.1
ENST00000524826.1
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr8_-_103136481 1.42 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
neurocalcin delta
chrX_-_1571759 1.42 ENST00000381317.3
ENST00000416733.2
acetylserotonin O-methyltransferase-like
chr11_+_36317830 1.40 ENST00000530639.1
proline rich 5 like
chr5_-_1112141 1.38 ENST00000264930.5
solute carrier family 12 (potassium/chloride transporter), member 7
chr11_+_6502675 1.36 ENST00000254616.6
ENST00000530751.1
translocase of inner mitochondrial membrane 10 homolog B (yeast)
chr5_+_149109825 1.34 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr19_-_3606590 1.32 ENST00000411851.3
thromboxane A2 receptor
chrX_-_153707246 1.31 ENST00000407062.1
L antigen family, member 3
chr14_-_106453155 1.28 ENST00000390594.2
immunoglobulin heavy variable 1-2
chr8_-_144691718 1.28 ENST00000377579.3
ENST00000433751.1
ENST00000220966.6
pyrroline-5-carboxylate reductase-like
chr5_+_134240800 1.28 ENST00000512783.1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr22_+_22681656 1.26 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr17_+_31254892 1.23 ENST00000394642.3
ENST00000579849.1
transmembrane protein 98
chr9_-_125693757 1.19 ENST00000373656.3
zinc finger and BTB domain containing 26
chr12_+_122356488 1.19 ENST00000397454.2
WD repeat domain 66
chr14_-_67955426 1.17 ENST00000554480.1
transmembrane protein 229B
chr19_-_12251202 1.15 ENST00000334213.5
zinc finger protein 20
chr5_-_42825983 1.14 ENST00000506577.1
selenoprotein P, plasma, 1
chr13_+_37006398 1.13 ENST00000418263.1
cyclin A1
chr20_+_44098385 1.13 ENST00000217425.5
ENST00000339946.3
WAP four-disulfide core domain 2
chr5_-_693500 1.12 ENST00000360578.5
tubulin polymerization promoting protein
chr20_-_32262165 1.11 ENST00000606690.1
ENST00000246190.6
ENST00000439478.1
ENST00000375238.4
N-terminal EF-hand calcium binding protein 3
chr12_-_42877764 1.10 ENST00000455697.1
prickle homolog 1 (Drosophila)
chr16_+_1383602 1.08 ENST00000426824.3
ENST00000397488.2
ENST00000562208.1
ENST00000568887.1
BAI1-associated protein 3
chr3_-_121553830 1.07 ENST00000498104.1
ENST00000460108.1
ENST00000349820.6
ENST00000462442.1
ENST00000310864.6
IQ motif containing B1
chr12_+_112204691 1.07 ENST00000416293.3
ENST00000261733.2
aldehyde dehydrogenase 2 family (mitochondrial)
chr17_-_5026397 1.06 ENST00000250076.3
zinc finger protein 232
chr10_+_74870206 1.06 ENST00000357321.4
ENST00000349051.5
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr6_-_111804905 1.06 ENST00000358835.3
ENST00000435970.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr16_+_69985083 1.05 ENST00000288040.6
ENST00000449317.2
C-type lectin domain family 18, member A
chr1_-_167906020 1.05 ENST00000458574.1
mitochondrial pyruvate carrier 2
chrX_-_1571810 1.04 ENST00000381333.4
acetylserotonin O-methyltransferase-like
chr2_-_160761179 1.04 ENST00000554112.1
ENST00000553424.1
ENST00000263636.4
ENST00000504764.1
ENST00000505052.1
lymphocyte antigen 75
LY75-CD302 readthrough
chr19_+_9434841 1.04 ENST00000446085.4
ENST00000603656.1
ENST00000541595.2
ENST00000592504.1
ENST00000585352.1
ENST00000317221.7
ENST00000586255.1
ENST00000592896.1
ENST00000605750.1
ENST00000603380.1
ENST00000538743.1
ENST00000589208.1
ENST00000592298.1
ENST00000585377.1
ENST00000393883.2
ENST00000588124.1
ENST00000602738.1
ZNF559-ZNF177 readthrough
zinc finger protein 559
zinc finger protein 177
chr4_-_1670632 1.04 ENST00000461064.1
family with sequence similarity 53, member A
chr3_+_88108381 1.03 ENST00000473136.1
Uncharacterized protein
chr16_+_2079501 1.01 ENST00000563587.1
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr19_+_17403413 1.01 ENST00000595444.1
ENST00000600434.1
mitochondrial ribosomal protein L34
chr17_+_29718642 1.00 ENST00000325874.8
RAB11 family interacting protein 4 (class II)
chr19_-_7562334 0.98 ENST00000593942.1
peroxisomal biogenesis factor 11 gamma
chr9_+_140125385 0.98 ENST00000361134.2
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr11_+_1942580 0.97 ENST00000381558.1
troponin T type 3 (skeletal, fast)
chr1_-_236445251 0.97 ENST00000354619.5
ENST00000327333.8
ERO1-like beta (S. cerevisiae)
chr10_+_74870253 0.96 ENST00000544879.1
ENST00000537969.1
ENST00000372997.3
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr4_-_101111615 0.95 ENST00000273990.2
DNA-damage-inducible transcript 4-like
chr14_+_52781079 0.95 ENST00000245457.5
prostaglandin E receptor 2 (subtype EP2), 53kDa
chr16_-_55866997 0.94 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chr1_-_167905225 0.94 ENST00000367846.4
mitochondrial pyruvate carrier 2
chr13_+_37006421 0.93 ENST00000255465.4
cyclin A1
chr9_-_112260531 0.92 ENST00000374541.2
ENST00000262539.3
protein tyrosine phosphatase, non-receptor type 3
chr1_+_206972215 0.91 ENST00000340758.2
interleukin 19
chr17_+_79968655 0.91 ENST00000583744.1
alveolar soft part sarcoma chromosome region, candidate 1
chr1_-_16556038 0.91 ENST00000375605.2
chromosome 1 open reading frame 134
chr22_+_23077065 0.90 ENST00000390310.2
immunoglobulin lambda variable 2-18
chr6_-_78173490 0.89 ENST00000369947.2
5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
chr11_+_1855645 0.88 ENST00000381968.3
ENST00000381978.3
synaptotagmin VIII
chr2_-_233877912 0.87 ENST00000264051.3
neuronal guanine nucleotide exchange factor
chr20_-_4982132 0.86 ENST00000338244.1
ENST00000424750.2
solute carrier family 23 (ascorbic acid transporter), member 2
chr10_+_76586348 0.86 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
K(lysine) acetyltransferase 6B
chr17_-_19619917 0.85 ENST00000325411.5
ENST00000350657.5
ENST00000433844.2
solute carrier family 47 (multidrug and toxin extrusion), member 2
chr19_-_2740036 0.85 ENST00000586572.1
ENST00000269740.4
Uncharacterized protein
solute carrier family 39 (zinc transporter), member 3
chr3_+_169684553 0.85 ENST00000337002.4
ENST00000480708.1
SEC62 homolog (S. cerevisiae)
chr1_-_46642154 0.85 ENST00000540385.1
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr9_+_116111794 0.85 ENST00000374183.4
B-box and SPRY domain containing
chr2_+_119981384 0.84 ENST00000393108.2
ENST00000354888.5
ENST00000450943.2
ENST00000393110.2
ENST00000393106.2
ENST00000409811.1
ENST00000393107.2
STEAP family member 3, metalloreductase
chr14_-_21492251 0.82 ENST00000554398.1
NDRG family member 2
chr6_+_149068464 0.82 ENST00000367463.4
uronyl-2-sulfotransferase
chr1_-_98386543 0.82 ENST00000423006.2
ENST00000370192.3
ENST00000306031.5
dihydropyrimidine dehydrogenase
chr14_-_21492113 0.81 ENST00000554094.1
NDRG family member 2
chr13_+_37005967 0.81 ENST00000440264.1
ENST00000449823.1
cyclin A1
chr16_+_28858004 0.80 ENST00000322610.8
SH2B adaptor protein 1
chr8_-_101348408 0.80 ENST00000519527.1
ENST00000522369.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chrX_-_129402857 0.79 ENST00000447817.1
ENST00000370978.4
zinc finger protein 280C
chr12_+_124457670 0.79 ENST00000539644.1
zinc finger protein 664
chr9_-_120177342 0.78 ENST00000361209.2
astrotactin 2
chr17_+_72426891 0.77 ENST00000392627.1
G protein-coupled receptor, family C, group 5, member C
chr19_+_1491144 0.76 ENST00000233596.3
receptor accessory protein 6
chr16_-_67493110 0.76 ENST00000602876.1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr2_+_204103663 0.76 ENST00000356079.4
ENST00000429815.2
cytochrome P450, family 20, subfamily A, polypeptide 1
chr1_+_94883991 0.76 ENST00000370214.4
ATP-binding cassette, sub-family D (ALD), member 3
chr16_+_70207686 0.76 ENST00000541793.2
ENST00000314151.8
ENST00000565806.1
ENST00000569347.2
ENST00000536907.2
C-type lectin domain family 18, member C
chr5_-_133304473 0.75 ENST00000231512.3
chromosome 5 open reading frame 15
chr12_-_50298000 0.75 ENST00000550635.2
Fas apoptotic inhibitory molecule 2
chr7_-_6746474 0.75 ENST00000394917.3
ENST00000405858.1
ENST00000342651.5
zinc finger protein 12
chr1_+_246729724 0.75 ENST00000366513.4
ENST00000366512.3
consortin, connexin sorting protein
chr3_-_15106747 0.75 ENST00000449354.2
ENST00000444840.2
ENST00000253686.2
mitochondrial ribosomal protein S25
chr22_+_22936998 0.75 ENST00000390303.2
immunoglobulin lambda variable 3-32 (non-functional)
chr16_+_89894875 0.74 ENST00000393062.2
spire-type actin nucleation factor 2
chr16_-_3086927 0.74 ENST00000572449.1
coiled-coil domain containing 64B
chr6_-_49712147 0.73 ENST00000433368.2
ENST00000354620.4
cysteine-rich secretory protein 3
chr9_-_33264557 0.73 ENST00000473781.1
ENST00000488499.1
BCL2-associated athanogene
chr16_+_89894911 0.72 ENST00000378247.3
ENST00000563972.1
spire-type actin nucleation factor 2
chr2_-_233415220 0.72 ENST00000408957.3
tigger transposable element derived 1
chr19_-_19843900 0.72 ENST00000344099.3
zinc finger protein 14
chr7_-_10979750 0.72 ENST00000339600.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr20_+_3801162 0.72 ENST00000379573.2
ENST00000379567.2
ENST00000455742.1
ENST00000246041.2
adaptor-related protein complex 5, sigma 1 subunit
chr12_+_31812121 0.72 ENST00000395763.3
methyltransferase like 20
chr9_-_115653176 0.71 ENST00000374228.4
solute carrier family 46, member 2
chr5_+_170288856 0.71 ENST00000523189.1
RAN binding protein 17
chr3_-_49466686 0.71 ENST00000273598.3
ENST00000436744.2
nicolin 1
chr22_+_42470244 0.71 ENST00000321753.3
family with sequence similarity 109, member B
chr9_-_130661916 0.70 ENST00000373142.1
ENST00000373146.1
ENST00000373144.3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr11_+_94277017 0.70 ENST00000358752.2
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr19_-_35719609 0.69 ENST00000324675.3
family with sequence similarity 187, member B
chr12_-_51420128 0.69 ENST00000262051.7
ENST00000547732.1
ENST00000262052.5
ENST00000546488.1
ENST00000550714.1
ENST00000548193.1
ENST00000547579.1
ENST00000546743.1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr1_+_19923454 0.69 ENST00000602662.1
ENST00000602293.1
ENST00000322753.6
MINOS1-NBL1 readthrough
mitochondrial inner membrane organizing system 1
chr11_-_6502534 0.68 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
ADP-ribosylation factor interacting protein 2
chr1_+_27561104 0.68 ENST00000361771.3
WD and tetratricopeptide repeats 1
chr17_+_26698677 0.68 ENST00000457710.3
sterile alpha and TIR motif containing 1
chr11_-_47270341 0.68 ENST00000529444.1
ENST00000530453.1
ENST00000537863.1
ENST00000529788.1
ENST00000444355.2
ENST00000527256.1
ENST00000529663.1
ENST00000256997.3
acid phosphatase 2, lysosomal
chr19_+_49838653 0.67 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr13_+_95364963 0.67 ENST00000438290.2
SOX21 antisense RNA 1 (head to head)
chr2_-_198650037 0.67 ENST00000392296.4
boule-like RNA-binding protein

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.8 2.4 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.8 3.1 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.7 2.2 GO:2000308 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.7 2.9 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.7 2.8 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.6 2.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.6 1.7 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.6 14.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.5 2.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.5 3.7 GO:0018879 biphenyl metabolic process(GO:0018879)
0.5 2.0 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.5 3.0 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.5 5.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.5 1.5 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.4 1.7 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.4 2.0 GO:0019303 D-ribose catabolic process(GO:0019303)
0.4 3.2 GO:0072592 oxygen metabolic process(GO:0072592)
0.3 2.0 GO:0043366 beta selection(GO:0043366)
0.3 2.6 GO:0071233 cellular response to leucine(GO:0071233)
0.3 1.6 GO:0015692 lead ion transport(GO:0015692)
0.3 4.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 0.9 GO:0015882 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.3 4.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.3 2.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 2.6 GO:0006477 protein sulfation(GO:0006477)
0.2 1.9 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 0.9 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.2 0.9 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.2 1.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 3.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.2 2.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 0.6 GO:1900157 negative regulation of osteoclast proliferation(GO:0090291) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2 1.5 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.2 0.6 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.2 0.8 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.2 1.0 GO:1901090 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.2 0.6 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.2 3.5 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 0.7 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.2 0.5 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2 1.6 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 1.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 0.5 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.2 1.4 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 0.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.3 GO:0097067 response to thyroid hormone(GO:0097066) cellular response to thyroid hormone stimulus(GO:0097067)
0.1 5.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 1.0 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.5 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.1 1.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.7 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.4 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.4 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.1 1.8 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 0.5 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.5 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.5 GO:0097676 cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 dimethylation(GO:0097676)
0.1 1.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.9 GO:0015866 ADP transport(GO:0015866)
0.1 0.5 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.1 0.6 GO:1902822 regulation of late endosome to lysosome transport(GO:1902822)
0.1 0.3 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.8 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.4 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.6 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 1.6 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.7 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.6 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 1.4 GO:0038203 TORC2 signaling(GO:0038203)
0.1 2.9 GO:0007141 male meiosis I(GO:0007141)
0.1 0.4 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.8 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 0.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.7 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.1 0.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.4 GO:0019046 release from viral latency(GO:0019046)
0.1 0.7 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 2.1 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 1.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.3 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 5.0 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 1.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.2 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.1 0.3 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 6.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 2.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 1.6 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.7 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1 0.5 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.1 0.4 GO:0036100 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1 0.1 GO:0036146 cellular response to mycotoxin(GO:0036146)
0.1 2.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.6 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.8 GO:0021759 globus pallidus development(GO:0021759)
0.1 1.4 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 0.2 GO:0097359 UDP-glucosylation(GO:0097359)
0.1 0.5 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.2 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.1 0.6 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.1 GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.1 0.2 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.2 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 7.5 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 0.4 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.2 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 0.3 GO:0051013 microtubule severing(GO:0051013)
0.1 0.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.4 GO:0046618 drug export(GO:0046618)
0.0 5.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.0 GO:0002467 germinal center formation(GO:0002467)
0.0 0.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.1 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.3 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.4 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 2.3 GO:0031648 protein destabilization(GO:0031648)
0.0 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.3 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 1.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.8 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.2 GO:0003341 cilium movement(GO:0003341)
0.0 0.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.8 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 1.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 1.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.4 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.0 0.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 1.4 GO:0007586 digestion(GO:0007586)
0.0 0.4 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.6 GO:0097502 mannosylation(GO:0097502)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.6 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.7 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.3 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.6 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.6 GO:0042832 defense response to protozoan(GO:0042832)
0.0 1.0 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.3 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 2.6 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.0 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.2 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 0.5 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.2 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553) olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.1 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.0 0.1 GO:1900738 cytolysis in other organism involved in symbiotic interaction(GO:0051801) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.8 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.3 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0016598 protein arginylation(GO:0016598)
0.0 0.3 GO:0072488 carnitine shuttle(GO:0006853) ammonium transmembrane transport(GO:0072488) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 1.9 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0045759 negative regulation of action potential(GO:0045759) negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.2 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.3 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.3 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 3.0 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.9 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.6 GO:0006525 arginine metabolic process(GO:0006525)
0.0 1.5 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.4 GO:0015695 organic cation transport(GO:0015695)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0 1.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.6 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.0 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.0 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.4 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0006970 response to osmotic stress(GO:0006970)
0.0 1.4 GO:0008033 tRNA processing(GO:0008033)
0.0 0.9 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.2 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 1.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.4 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0090500 negative regulation of endothelial cell differentiation(GO:0045602) endocardial cushion to mesenchymal transition(GO:0090500)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 3.0 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.4 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.4 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.4 GO:0006301 postreplication repair(GO:0006301)
0.0 1.0 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.7 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.6 6.2 GO:0097427 microtubule bundle(GO:0097427)
0.6 2.9 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.5 3.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.4 2.6 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.4 1.2 GO:0001534 radial spoke(GO:0001534)
0.3 1.6 GO:0070826 paraferritin complex(GO:0070826)
0.3 2.2 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.2 7.0 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 0.8 GO:0060187 cell pole(GO:0060187)
0.2 1.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 1.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 1.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 0.8 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.2 2.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 8.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.4 GO:0044753 amphisome(GO:0044753)
0.1 6.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.8 GO:0061617 MICOS complex(GO:0061617)
0.1 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.4 GO:0032044 DSIF complex(GO:0032044)
0.1 5.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.5 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 1.4 GO:0090543 Flemming body(GO:0090543)
0.1 2.0 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.9 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 1.4 GO:0031932 TORC2 complex(GO:0031932)
0.1 2.0 GO:0042101 T cell receptor complex(GO:0042101)
0.1 3.8 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.6 GO:0060091 kinocilium(GO:0060091)
0.1 2.8 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 1.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 3.7 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 2.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 1.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 2.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 6.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.4 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0005713 recombination nodule(GO:0005713)
0.0 0.4 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 1.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 1.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.8 GO:0005771 multivesicular body(GO:0005771)
0.0 1.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 7.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.4 GO:0097060 synaptic membrane(GO:0097060)
0.0 10.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.3 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 9.7 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
1.3 5.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.0 3.8 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.8 2.4 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.7 3.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.6 1.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.5 3.2 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.4 1.3 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.4 2.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.4 2.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.4 7.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.4 4.1 GO:0031013 troponin I binding(GO:0031013)
0.4 2.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.3 1.6 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.3 2.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3 1.0 GO:0090541 MIT domain binding(GO:0090541)
0.3 3.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.3 0.9 GO:0008523 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.3 5.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.2 2.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.2 1.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 3.9 GO:0015643 toxic substance binding(GO:0015643)
0.2 0.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 0.8 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.2 2.6 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.2 2.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 1.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 0.9 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 0.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 3.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 2.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 1.5 GO:1901612 cardiolipin binding(GO:1901612)
0.2 1.6 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.2 2.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 1.4 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.2 0.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.4 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.5 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 1.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.8 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.4 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 1.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 1.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 2.8 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 6.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 2.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.3 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.4 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.8 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 1.0 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.4 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.6 GO:0019863 IgE binding(GO:0019863)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.4 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 0.4 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.1 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.4 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.3 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.6 GO:0016015 morphogen activity(GO:0016015)
0.1 2.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 2.1 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.7 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.2 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.1 1.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.6 GO:0071253 connexin binding(GO:0071253)
0.1 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.2 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 1.0 GO:0070330 aromatase activity(GO:0070330)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.5 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 1.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 1.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.8 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.7 GO:0051400 BH domain binding(GO:0051400)
0.0 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 2.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 1.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 1.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.5 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.4 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 3.0 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0004057 arginyltransferase activity(GO:0004057)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.5 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 3.6 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 1.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 1.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.5 GO:0008483 transaminase activity(GO:0008483)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 1.5 GO:0051087 chaperone binding(GO:0051087)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 2.2 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.4 GO:0016798 hydrolase activity, acting on glycosyl bonds(GO:0016798)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 5.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 1.9 PID ARF 3PATHWAY Arf1 pathway
0.1 2.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 3.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.4 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 3.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 13.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.4 4.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 2.7 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 0.8 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 2.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 2.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.6 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 2.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 3.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 3.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 3.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 3.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 6.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 5.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.9 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.2 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.8 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism