Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for ETV7
Z-value: 1.25
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Transcription factors associated with ETV7
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ETV7 | hg19_v2_chr6_-_36355513_36355578 | -0.10 | 6.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_+_9479944 Show fit | 4.47 |
ENST00000396219.3
ENST00000352665.5 |
WD repeat domain 16 |
|
| chr3_+_63638339 Show fit | 4.35 |
ENST00000343837.3
ENST00000469440.1 |
sentan, cilia apical structure protein |
|
| chr3_-_19988462 Show fit | 4.31 |
ENST00000344838.4
|
EF-hand domain family, member B |
|
| chr11_+_61976137 Show fit | 3.73 |
ENST00000244930.4
|
secretoglobin, family 2A, member 1 |
|
| chr12_-_58329819 Show fit | 3.67 |
ENST00000551421.1
|
RP11-620J15.3 |
|
| chr14_-_21270561 Show fit | 3.54 |
ENST00000412779.2
|
ribonuclease, RNase A family, 1 (pancreatic) |
|
| chr21_-_46340770 Show fit | 3.40 |
ENST00000397854.3
|
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
|
| chr11_+_73676281 Show fit | 3.31 |
ENST00000543947.1
|
DnaJ (Hsp40) homolog, subfamily B, member 13 |
|
| chr17_-_19281203 Show fit | 3.29 |
ENST00000487415.2
|
B9 protein domain 1 |
|
| chr7_-_99569468 Show fit | 3.25 |
ENST00000419575.1
|
alpha-2-glycoprotein 1, zinc-binding |
Network of associatons between targets according to the STRING database.
First level regulatory network of ETV7
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 10.5 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
| 1.3 | 6.4 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 0.1 | 5.9 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 0.2 | 5.7 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
| 0.2 | 5.1 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.1 | 3.7 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.2 | 3.6 | GO:0010826 | negative regulation of centrosome duplication(GO:0010826) |
| 0.1 | 3.3 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.1 | 3.2 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.6 | 3.1 | GO:0019303 | D-ribose catabolic process(GO:0019303) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 11.4 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.1 | 6.7 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.3 | 6.5 | GO:0036038 | MKS complex(GO:0036038) |
| 0.7 | 5.8 | GO:0034688 | integrin alphaM-beta2 complex(GO:0034688) |
| 0.3 | 5.4 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.3 | 3.2 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.0 | 2.4 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.2 | 2.3 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.0 | 2.3 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 2.2 | GO:0005581 | collagen trimer(GO:0005581) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 11.4 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.2 | 8.1 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.6 | 5.9 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
| 0.0 | 5.8 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.2 | 5.1 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 4.1 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.5 | 3.5 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.4 | 3.3 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
| 0.1 | 3.3 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 3.1 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.6 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.1 | 5.1 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 5.1 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 3.5 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 3.0 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 2.2 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 2.1 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.8 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 1.5 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.3 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 10.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 4.7 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 3.3 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.2 | 3.2 | REACTOME SIGNALING BY NOTCH2 | Genes involved in Signaling by NOTCH2 |
| 0.0 | 2.7 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 1.9 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 1.7 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.0 | 1.2 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 1.1 | REACTOME EICOSANOID LIGAND BINDING RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.0 | 1.1 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |