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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for EVX2

Z-value: 0.34

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Transcription factors associated with EVX2

Gene Symbol Gene ID Gene Info
EVX2
ENSG00000174279.4 even-skipped homeobox 2

Activity profile of EVX2 motif

Sorted Z-values of EVX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_111718173 1.14 ENST00000494932.1
TAGLN3
transgelin 3
chr11_-_115375107 1.10 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr3_+_111717600 0.94 ENST00000273368.4
TAGLN3
transgelin 3
chr3_+_111718036 0.91 ENST00000455401.2
TAGLN3
transgelin 3
chr3_+_111717511 0.88 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr20_-_50418972 0.48 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr20_-_50418947 0.46 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr20_-_50419055 0.30 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr13_+_78315466 0.27 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr1_+_28261492 0.24 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr20_+_43990576 0.24 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr1_+_28261621 0.22 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr5_-_96478466 0.21 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr4_+_144354644 0.20 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr4_-_41884620 0.17 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr4_-_41884582 0.12 ENST00000499082.2
LINC00682
long intergenic non-protein coding RNA 682
chr6_+_39760129 0.12 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr1_-_151431647 0.11 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr1_+_28261533 0.09 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr12_+_28410128 0.08 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr1_-_151431909 0.05 ENST00000361398.3
ENST00000271715.2
POGZ
pogo transposable element with ZNF domain
chr17_+_18086392 0.05 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr6_-_62996066 0.04 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr17_-_9929581 0.03 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr6_-_111927062 0.03 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr19_+_11071546 0.01 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr6_-_111927449 0.01 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3IP2
TRAF3 interacting protein 2

Network of associatons between targets according to the STRING database.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 1.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.9 GO:0043209 myelin sheath(GO:0043209)
0.0 1.2 GO:0000792 heterochromatin(GO:0000792)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 3.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.0 GO:0035515 oxidative RNA demethylase activity(GO:0035515)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions