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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for FIGLA

Z-value: 0.69

Motif logo

Transcription factors associated with FIGLA

Gene Symbol Gene ID Gene Info
ENSG00000183733.6 folliculogenesis specific bHLH transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FIGLAhg19_v2_chr2_-_71017775_710177750.328.5e-02Click!

Activity profile of FIGLA motif

Sorted Z-values of FIGLA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_39382900 2.90 ENST00000377721.3
ENST00000455970.2
keratin associated protein 9-2
chr17_-_39280419 1.70 ENST00000394014.1
keratin associated protein 4-12
chr11_+_118175596 1.32 ENST00000528600.1
CD3e molecule, epsilon (CD3-TCR complex)
chr11_+_118175132 1.30 ENST00000361763.4
CD3e molecule, epsilon (CD3-TCR complex)
chr6_-_39290316 1.21 ENST00000425054.2
ENST00000373227.4
ENST00000373229.5
ENST00000437525.2
potassium channel, subfamily K, member 16
chr17_-_39211463 1.20 ENST00000542910.1
ENST00000398477.1
keratin associated protein 2-2
chr3_+_49059038 1.20 ENST00000451378.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr17_+_39411636 1.01 ENST00000394008.1
keratin associated protein 9-9
chr17_+_39261584 0.95 ENST00000391415.1
keratin associated protein 4-9
chr20_+_44441215 0.95 ENST00000356455.4
ENST00000405520.1
ubiquitin-conjugating enzyme E2C
chr20_+_44441304 0.94 ENST00000352551.5
ubiquitin-conjugating enzyme E2C
chr1_-_230561475 0.92 ENST00000391860.1
piggyBac transposable element derived 5
chr17_+_39394250 0.78 ENST00000254072.6
keratin associated protein 9-8
chr2_+_42104692 0.78 ENST00000398796.2
ENST00000442214.1
AC104654.1
chr11_-_123525289 0.75 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
sodium channel, voltage-gated, type III, beta subunit
chr4_+_165675269 0.72 ENST00000507311.1
RP11-294O2.2
chr4_+_165675197 0.70 ENST00000515485.1
RP11-294O2.2
chr5_-_159739532 0.67 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
cyclin J-like
chr17_-_39334460 0.63 ENST00000377726.2
keratin associated protein 4-2
chr2_-_175629135 0.62 ENST00000409542.1
ENST00000409219.1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr11_+_118958689 0.61 ENST00000535253.1
ENST00000392841.1
hydroxymethylbilane synthase
chr17_+_48133459 0.59 ENST00000320031.8
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr1_-_11120057 0.59 ENST00000376957.2
spermidine synthase
chr7_-_99698338 0.59 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr11_+_60223312 0.58 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
membrane-spanning 4-domains, subfamily A, member 1
chr6_+_96463840 0.58 ENST00000302103.5
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr19_+_50180317 0.57 ENST00000534465.1
protein arginine methyltransferase 1
chr6_+_41888926 0.54 ENST00000230340.4
bystin-like
chr17_-_39306054 0.50 ENST00000343246.4
keratin associated protein 4-5
chr11_+_60223225 0.48 ENST00000524807.1
ENST00000345732.4
membrane-spanning 4-domains, subfamily A, member 1
chr19_-_51456198 0.48 ENST00000594846.1
kallikrein-related peptidase 5
chr7_+_2687173 0.46 ENST00000403167.1
tweety family member 3
chr3_+_172468472 0.46 ENST00000232458.5
ENST00000392692.3
epithelial cell transforming sequence 2 oncogene
chr17_-_39203519 0.45 ENST00000542137.1
ENST00000391419.3
keratin associated protein 2-1
chr7_-_44229022 0.44 ENST00000403799.3
glucokinase (hexokinase 4)
chr4_-_139163491 0.44 ENST00000280612.5
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr3_-_49967292 0.41 ENST00000455683.2
MON1 secretory trafficking family member A
chrX_-_30326445 0.41 ENST00000378963.1
nuclear receptor subfamily 0, group B, member 1
chr17_+_39240459 0.39 ENST00000391417.4
keratin associated protein 4-7
chr10_-_33625154 0.39 ENST00000265371.4
neuropilin 1
chr22_-_37823468 0.39 ENST00000402918.2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr17_-_39316983 0.38 ENST00000390661.3
keratin associated protein 4-4
chr16_+_30006615 0.38 ENST00000563197.1
INO80 complex subunit E
chr2_-_175629164 0.38 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr12_+_48357340 0.38 ENST00000256686.6
ENST00000549288.1
ENST00000552561.1
ENST00000546749.1
ENST00000552546.1
ENST00000550552.1
transmembrane protein 106C
chr12_+_32655110 0.37 ENST00000546442.1
ENST00000583694.1
FYVE, RhoGEF and PH domain containing 4
chr17_-_48133054 0.37 ENST00000499842.1
RP11-1094H24.4
chr12_-_52585765 0.37 ENST00000313234.5
ENST00000394815.2
keratin 80
chr15_+_89182178 0.36 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr12_+_48357401 0.35 ENST00000429772.2
ENST00000449758.2
transmembrane protein 106C
chrX_-_137793826 0.34 ENST00000315930.6
fibroblast growth factor 13
chr17_+_8243154 0.32 ENST00000328248.2
ENST00000584943.1
outer dense fiber of sperm tails 4
chr1_+_22328144 0.32 ENST00000290122.3
ENST00000374663.1
chymotrypsin-like elastase family, member 3A
chr3_-_50360192 0.32 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
hyaluronoglucosaminidase 2
chr1_+_183155373 0.31 ENST00000493293.1
ENST00000264144.4
laminin, gamma 2
chr19_-_42916499 0.30 ENST00000601189.1
ENST00000599211.1
lipase, hormone-sensitive
chr12_+_58176525 0.30 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
Ts translation elongation factor, mitochondrial
chr15_+_90728145 0.30 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr9_+_33795533 0.30 ENST00000379405.3
protease, serine, 3
chr12_-_118406777 0.30 ENST00000339824.5
kinase suppressor of ras 2
chr2_-_152590946 0.29 ENST00000172853.10
nebulin
chr17_+_40985407 0.29 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr4_-_90757364 0.29 ENST00000508895.1
synuclein, alpha (non A4 component of amyloid precursor)
chr10_-_30638090 0.29 ENST00000421701.1
ENST00000263063.4
mitochondrial poly(A) polymerase
chr7_+_18535854 0.29 ENST00000401921.1
histone deacetylase 9
chr2_+_136289030 0.28 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3H domain containing 1
chr20_-_22566089 0.28 ENST00000377115.4
forkhead box A2
chr2_-_163008903 0.28 ENST00000418842.2
ENST00000375497.3
glucagon
chr5_-_54281407 0.28 ENST00000381403.4
endothelial cell-specific molecule 1
chr11_-_84634217 0.28 ENST00000524982.1
discs, large homolog 2 (Drosophila)
chr1_+_22303503 0.28 ENST00000337107.6
chymotrypsin-like elastase family, member 3B
chr7_+_128784712 0.27 ENST00000289407.4
tetraspanin 33
chr15_+_89181974 0.27 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr11_-_84634447 0.27 ENST00000532653.1
discs, large homolog 2 (Drosophila)
chr6_+_7107830 0.27 ENST00000379933.3
ras responsive element binding protein 1
chr19_-_40791211 0.27 ENST00000579047.1
v-akt murine thymoma viral oncogene homolog 2
chr6_+_44184653 0.26 ENST00000573382.2
ENST00000576476.1
RP1-302G2.5
chr8_-_49834299 0.26 ENST00000396822.1
snail family zinc finger 2
chr5_+_150827143 0.26 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
solute carrier family 36 (proton/amino acid symporter), member 1
chr9_-_139258159 0.25 ENST00000371739.3
DNL-type zinc finger
chr5_+_68788594 0.25 ENST00000396442.2
ENST00000380766.2
occludin
chr15_+_89182156 0.25 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr2_+_136343820 0.25 ENST00000410054.1
R3H domain containing 1
chr2_+_241375069 0.24 ENST00000264039.2
glypican 1
chr8_-_49833978 0.24 ENST00000020945.1
snail family zinc finger 2
chrX_-_107975917 0.24 ENST00000563887.1
Uncharacterized protein
chr13_-_20767037 0.24 ENST00000382848.4
gap junction protein, beta 2, 26kDa
chr2_+_170590321 0.24 ENST00000392647.2
kelch-like family member 23
chr1_+_22307592 0.23 ENST00000400277.2
chymotrypsin-like elastase family, member 3B
chr7_+_77428066 0.23 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
putative homeodomain transcription factor 2
chr17_+_39405939 0.23 ENST00000334109.2
keratin associated protein 9-4
chr5_-_16936340 0.23 ENST00000507288.1
ENST00000513610.1
myosin X
chr1_-_40367530 0.23 ENST00000372816.2
ENST00000372815.1
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr2_-_136288740 0.22 ENST00000264159.6
ENST00000536680.1
zinc finger, RAN-binding domain containing 3
chr16_+_30006997 0.22 ENST00000304516.7
INO80 complex subunit E
chr2_-_27603582 0.22 ENST00000323703.6
ENST00000436006.1
zinc finger protein 513
chr3_+_111393501 0.22 ENST00000393934.3
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr6_+_7108210 0.22 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
ras responsive element binding protein 1
chr3_+_35721106 0.22 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
cAMP-regulated phosphoprotein, 21kDa
chr6_+_12717892 0.21 ENST00000379350.1
phosphatase and actin regulator 1
chr12_-_118406028 0.21 ENST00000425217.1
kinase suppressor of ras 2
chr5_-_132948216 0.21 ENST00000265342.7
follistatin-like 4
chr6_+_34204642 0.21 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr4_+_6271558 0.21 ENST00000503569.1
ENST00000226760.1
Wolfram syndrome 1 (wolframin)
chr1_+_26737253 0.21 ENST00000326279.6
lin-28 homolog A (C. elegans)
chr6_-_31697255 0.21 ENST00000436437.1
dimethylarginine dimethylaminohydrolase 2
chr11_+_128634589 0.21 ENST00000281428.8
Fli-1 proto-oncogene, ETS transcription factor
chr17_+_7462103 0.21 ENST00000396545.4
tumor necrosis factor (ligand) superfamily, member 13
chr1_+_144989309 0.20 ENST00000596396.1
Uncharacterized protein
chr8_-_28347737 0.20 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
F-box protein 16
chr6_+_46761118 0.20 ENST00000230588.4
meprin A, alpha (PABA peptide hydrolase)
chr11_-_118972575 0.20 ENST00000432443.2
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr14_-_20923195 0.20 ENST00000206542.4
O-sialoglycoprotein endopeptidase
chr7_-_37488834 0.20 ENST00000310758.4
engulfment and cell motility 1
chr8_+_32405785 0.20 ENST00000287842.3
neuregulin 1
chr3_-_194991876 0.20 ENST00000310380.6
xyloside xylosyltransferase 1
chr5_+_6448736 0.20 ENST00000399816.3
ubiquitin-conjugating enzyme E2Q family-like 1
chr16_-_69418649 0.20 ENST00000566257.1
telomeric repeat binding factor 2
chr2_+_37571845 0.19 ENST00000537448.1
glutaminyl-peptide cyclotransferase
chr16_-_46864955 0.19 ENST00000565112.1
chromosome 16 open reading frame 87
chr1_-_201391149 0.19 ENST00000555948.1
ENST00000556362.1
troponin I type 1 (skeletal, slow)
chr22_+_22988816 0.19 ENST00000480559.1
ENST00000448514.1
gamma-glutamyltransferase light chain 2
chr6_+_22569784 0.19 ENST00000510882.2
hepatoma derived growth factor-like 1
chr11_+_69455855 0.19 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr8_+_145438870 0.19 ENST00000527931.1
family with sequence similarity 203, member B
chr1_-_183622442 0.19 ENST00000308641.4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr17_+_7461849 0.18 ENST00000338784.4
tumor necrosis factor (ligand) superfamily, member 13
chr1_-_171621815 0.18 ENST00000037502.6
myocilin, trabecular meshwork inducible glucocorticoid response
chr2_+_37571717 0.18 ENST00000338415.3
ENST00000404976.1
glutaminyl-peptide cyclotransferase
chr11_-_88070920 0.18 ENST00000524463.1
ENST00000227266.5
cathepsin C
chr2_-_152590982 0.18 ENST00000409198.1
ENST00000397345.3
ENST00000427231.2
nebulin
chr11_-_62911693 0.18 ENST00000417740.1
ENST00000326192.5
solute carrier family 22, member 24
chr7_-_11871815 0.17 ENST00000423059.4
thrombospondin, type I, domain containing 7A
chr11_-_118122996 0.17 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
myelin protein zero-like 3
chr8_-_93029520 0.17 ENST00000521553.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_+_115614370 0.17 ENST00000369301.3
NHL repeat containing 2
chrX_-_134049233 0.17 ENST00000370779.4
motile sperm domain containing 1
chr2_-_128051670 0.16 ENST00000493187.2
excision repair cross-complementing rodent repair deficiency, complementation group 3
chr11_+_130318869 0.16 ENST00000299164.2
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr14_+_75746340 0.16 ENST00000555686.1
ENST00000555672.1
FBJ murine osteosarcoma viral oncogene homolog
chr1_-_42384343 0.16 ENST00000372584.1
human immunodeficiency virus type I enhancer binding protein 3
chr22_+_31090793 0.16 ENST00000332585.6
ENST00000382310.3
ENST00000446658.2
oxysterol binding protein 2
chr7_-_148725733 0.16 ENST00000286091.4
protein disulfide isomerase family A, member 4
chr5_+_140868717 0.16 ENST00000252087.1
protocadherin gamma subfamily C, 5
chr1_-_156675535 0.15 ENST00000368221.1
cellular retinoic acid binding protein 2
chr1_-_111991850 0.15 ENST00000411751.2
WD repeat domain 77
chr1_+_24646002 0.15 ENST00000356046.2
grainyhead-like 3 (Drosophila)
chr5_+_52856456 0.15 ENST00000296684.5
ENST00000506765.1
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr1_+_24645807 0.15 ENST00000361548.4
grainyhead-like 3 (Drosophila)
chr1_+_24645865 0.15 ENST00000342072.4
grainyhead-like 3 (Drosophila)
chr17_-_4458616 0.15 ENST00000381556.2
MYB binding protein (P160) 1a
chr1_-_53608289 0.14 ENST00000371491.4
solute carrier family 1 (glutamate transporter), member 7
chr3_-_128294929 0.14 ENST00000356020.2
chromosome 3 open reading frame 27
chr19_+_36347787 0.14 ENST00000347900.6
ENST00000360202.5
kin of IRRE like 2 (Drosophila)
chr19_+_36249044 0.14 ENST00000444637.2
ENST00000396908.4
ENST00000544099.1
chromosome 19 open reading frame 55
chr16_-_4465886 0.14 ENST00000539968.1
coronin 7
chr8_-_130951940 0.14 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
family with sequence similarity 49, member B
chr12_+_79258444 0.14 ENST00000261205.4
synaptotagmin I
chr8_-_145018905 0.14 ENST00000398774.2
plectin
chr2_-_179672142 0.14 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
titin
chr2_-_50574856 0.14 ENST00000342183.5
neurexin 1
chr14_+_75746781 0.14 ENST00000555347.1
FBJ murine osteosarcoma viral oncogene homolog
chr2_-_75788038 0.14 ENST00000393913.3
ENST00000410113.1
eva-1 homolog A (C. elegans)
chr17_+_7462031 0.13 ENST00000380535.4
tumor necrosis factor (ligand) superfamily, member 13
chr1_-_28969517 0.13 ENST00000263974.4
ENST00000373824.4
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr17_+_9548845 0.13 ENST00000570475.1
ENST00000285199.7
ubiquitin specific peptidase 43
chr4_-_57522470 0.13 ENST00000503639.3
HOP homeobox
chr3_-_46904946 0.13 ENST00000292327.4
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr17_+_79495397 0.13 ENST00000417245.2
ENST00000334850.7
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr17_-_34890665 0.12 ENST00000586007.1
myosin XIX
chr3_+_68055366 0.12 ENST00000496687.1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr16_+_6533380 0.12 ENST00000552089.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr17_-_39222131 0.12 ENST00000394015.2
keratin associated protein 2-4
chr3_-_46904918 0.12 ENST00000395869.1
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr14_+_31343747 0.12 ENST00000216361.4
ENST00000396618.3
ENST00000475087.1
cochlin
chr12_+_79258547 0.12 ENST00000457153.2
synaptotagmin I
chr6_+_109169591 0.12 ENST00000368972.3
ENST00000392644.4
armadillo repeat containing 2
chr1_-_156675368 0.12 ENST00000368222.3
cellular retinoic acid binding protein 2
chr19_+_16186903 0.12 ENST00000588507.1
tropomyosin 4
chrX_-_134049262 0.12 ENST00000370783.3
motile sperm domain containing 1
chr6_-_35888824 0.12 ENST00000361690.3
ENST00000512445.1
SRSF protein kinase 1
chr7_+_18535346 0.11 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
histone deacetylase 9
chr3_-_167191814 0.11 ENST00000466903.1
ENST00000264677.4
serpin peptidase inhibitor, clade I (pancpin), member 2
chr11_-_65629497 0.11 ENST00000532134.1
cofilin 1 (non-muscle)
chr16_+_32077386 0.11 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chrX_-_11445856 0.11 ENST00000380736.1
Rho GTPase activating protein 6
chrX_+_70443050 0.11 ENST00000361726.6
gap junction protein, beta 1, 32kDa
chr3_-_69435224 0.11 ENST00000398540.3
FERM domain containing 4B
chr17_-_39254391 0.11 ENST00000333822.4
keratin associated protein 4-8
chr1_+_155051305 0.11 ENST00000368408.3
ephrin-A3
chr16_+_30383613 0.11 ENST00000568749.1
myosin light chain, phosphorylatable, fast skeletal muscle
chr12_+_69201923 0.11 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2 oncogene, E3 ubiquitin protein ligase
chr14_-_107131560 0.11 ENST00000390632.2
immunoglobulin heavy variable 3-66
chr1_-_153585539 0.11 ENST00000368706.4
S100 calcium binding protein A16
chr1_+_45478568 0.10 ENST00000428106.1
uroporphyrinogen decarboxylase
chr6_-_19804973 0.10 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
chr6_-_31938700 0.10 ENST00000495340.1
decapping exoribonuclease
chr17_-_29624343 0.10 ENST00000247271.4
oligodendrocyte myelin glycoprotein
chr7_-_2883928 0.10 ENST00000275364.3
guanine nucleotide binding protein (G protein) alpha 12
chr14_+_62584197 0.10 ENST00000334389.4
long intergenic non-protein coding RNA 643

Network of associatons between targets according to the STRING database.

First level regulatory network of FIGLA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.6 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.2 1.9 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.2 0.9 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 0.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.6 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.7 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.4 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 1.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.3 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.7 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.3 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.5 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.6 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.6 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.5 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.3 GO:0019087 transformation of host cell by virus(GO:0019087)
0.1 0.4 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:0009644 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.1 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.2 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.2 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.1 0.3 GO:2000470 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.4 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.3 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.2 GO:0030167 proteoglycan catabolic process(GO:0030167) heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.5 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.6 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.3 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.3 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.6 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 7.0 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.3 GO:0090050 peptidyl-lysine deacetylation(GO:0034983) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.7 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.6 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.0 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.3 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.2 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.0 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0032425 positive regulation of mismatch repair(GO:0032425)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0051511 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.3 GO:0009235 cobalamin metabolic process(GO:0009235)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.6 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 8.9 GO:0045095 keratin filament(GO:0045095)
0.1 0.3 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.5 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.3 GO:0008537 proteasome activator complex(GO:0008537)
0.0 1.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.8 GO:0034709 methylosome(GO:0034709)
0.0 1.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0097443 sorting endosome(GO:0097443)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.6 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.0 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 2.6 GO:0042608 T cell receptor binding(GO:0042608)
0.2 0.6 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.4 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.7 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.4 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.3 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.6 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.3 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.6 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.4 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 1.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 2.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.1 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.4 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.0 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.5 ST JNK MAPK PATHWAY JNK MAPK Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis