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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for FOSB
Z-value: 0.53
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Transcription factors associated with FOSB
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOSB | hg19_v2_chr19_+_45971246_45971265 | -0.34 | 6.3e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_+_71560154 Show fit | 1.21 |
ENST00000539698.3
|
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
|
| chr7_+_23286182 Show fit | 1.19 |
ENST00000258733.4
ENST00000381990.2 ENST00000409458.3 ENST00000539136.1 ENST00000453162.2 |
glycoprotein (transmembrane) nmb |
|
| chr16_+_71560023 Show fit | 1.18 |
ENST00000572450.1
|
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
|
| chr1_-_160231451 Show fit | 1.18 |
ENST00000495887.1
|
DDB1 and CUL4 associated factor 8 |
|
| chr9_-_130637244 Show fit | 1.01 |
ENST00000373156.1
|
adenylate kinase 1 |
|
| chr6_+_33043703 Show fit | 0.91 |
ENST00000418931.2
ENST00000535465.1 |
major histocompatibility complex, class II, DP beta 1 |
|
| chr19_-_35981358 Show fit | 0.88 |
ENST00000484218.2
ENST00000338897.3 |
keratinocyte differentiation-associated protein |
|
| chr4_-_100356551 Show fit | 0.75 |
ENST00000209665.4
|
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
|
| chr4_-_100356844 Show fit | 0.73 |
ENST00000437033.2
|
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
|
| chr2_-_238499303 Show fit | 0.72 |
ENST00000409576.1
|
RAB17, member RAS oncogene family |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOSB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.4 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.7 | 2.2 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 0.2 | 1.7 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 0.3 | 1.4 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 0.0 | 1.4 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 1.3 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.0 | 1.2 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
| 0.0 | 0.9 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.2 | 0.8 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
| 0.0 | 0.6 | GO:0016540 | protein autoprocessing(GO:0016540) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.7 | GO:0031228 | intrinsic component of Golgi membrane(GO:0031228) |
| 0.0 | 1.2 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 1.2 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.9 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 0.9 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.0 | 0.9 | GO:0042599 | lamellar body(GO:0042599) |
| 0.2 | 0.5 | GO:0097447 | dendritic tree(GO:0097447) |
| 0.2 | 0.5 | GO:0020003 | symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) |
| 0.1 | 0.5 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.1 | 0.5 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 2.4 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.5 | 2.2 | GO:0004031 | aldehyde oxidase activity(GO:0004031) |
| 0.1 | 1.7 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.0 | 1.4 | GO:0019003 | GDP binding(GO:0019003) |
| 0.1 | 1.2 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.0 | 1.1 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.1 | 1.0 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.0 | 0.9 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.2 | 0.5 | GO:0035379 | carbon dioxide transmembrane transporter activity(GO:0035379) |
| 0.0 | 0.5 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 1.3 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.1 | 0.4 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.2 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.9 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 0.7 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.0 | 0.7 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.6 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.5 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 0.3 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.3 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.0 | 0.3 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 0.3 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |