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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for FOSL1
Z-value: 2.20
Motif logo
Transcription factors associated with FOSL1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
FOSL1
|
ENSG00000175592.4 | FOS like 1, AP-1 transcription factor subunit |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOSL1 | hg19_v2_chr11_-_65667884_65667895 | 0.86 | 1.2e-09 | Click! |
Activity profile of FOSL1 motif
Sorted Z-values of FOSL1 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_-_36019123 | 22.14 |
ENST00000588674.1
ENST00000452271.2 ENST00000518157.1 |
SBSN
|
suprabasin |
| chr1_+_150480551 | 18.24 |
ENST00000369049.4
ENST00000369047.4 |
ECM1
|
extracellular matrix protein 1 |
| chr1_+_150480576 | 18.04 |
ENST00000346569.6
|
ECM1
|
extracellular matrix protein 1 |
| chr18_+_21452964 | 16.70 |
ENST00000587184.1
|
LAMA3
|
laminin, alpha 3 |
| chr18_+_21452804 | 14.36 |
ENST00000269217.6
|
LAMA3
|
laminin, alpha 3 |
| chr1_-_153029980 | 13.95 |
ENST00000392653.2
|
SPRR2A
|
small proline-rich protein 2A |
| chr1_+_183155373 | 13.82 |
ENST00000493293.1
ENST00000264144.4 |
LAMC2
|
laminin, gamma 2 |
| chr12_+_13349650 | 13.66 |
ENST00000256951.5
ENST00000431267.2 ENST00000542474.1 ENST00000544053.1 |
EMP1
|
epithelial membrane protein 1 |
| chr6_+_47666275 | 13.62 |
ENST00000327753.3
ENST00000283303.2 |
GPR115
|
G protein-coupled receptor 115 |
| chr1_-_153013588 | 13.62 |
ENST00000360379.3
|
SPRR2D
|
small proline-rich protein 2D |
| chr19_+_35645817 | 12.72 |
ENST00000423817.3
|
FXYD5
|
FXYD domain containing ion transport regulator 5 |
| chr17_-_39769005 | 12.64 |
ENST00000301653.4
ENST00000593067.1 |
KRT16
|
keratin 16 |
| chr19_+_35645618 | 12.55 |
ENST00000392218.2
ENST00000543307.1 ENST00000392219.2 ENST00000541435.2 ENST00000590686.1 ENST00000342879.3 ENST00000588699.1 |
FXYD5
|
FXYD domain containing ion transport regulator 5 |
| chr1_+_152956549 | 12.54 |
ENST00000307122.2
|
SPRR1A
|
small proline-rich protein 1A |
| chr1_-_153066998 | 12.25 |
ENST00000368750.3
|
SPRR2E
|
small proline-rich protein 2E |
| chr1_+_152881014 | 11.73 |
ENST00000368764.3
ENST00000392667.2 |
IVL
|
involucrin |
| chr10_+_17270214 | 10.83 |
ENST00000544301.1
|
VIM
|
vimentin |
| chr13_+_78109884 | 10.82 |
ENST00000377246.3
ENST00000349847.3 |
SCEL
|
sciellin |
| chr5_+_135394840 | 10.58 |
ENST00000503087.1
|
TGFBI
|
transforming growth factor, beta-induced, 68kDa |
| chr13_+_78109804 | 10.43 |
ENST00000535157.1
|
SCEL
|
sciellin |
| chr1_-_153521597 | 10.43 |
ENST00000368712.1
|
S100A3
|
S100 calcium binding protein A3 |
| chr2_+_113875466 | 10.32 |
ENST00000361779.3
ENST00000259206.5 ENST00000354115.2 |
IL1RN
|
interleukin 1 receptor antagonist |
| chr11_-_65667997 | 9.97 |
ENST00000312562.2
ENST00000534222.1 |
FOSL1
|
FOS-like antigen 1 |
| chr7_+_48128194 | 9.62 |
ENST00000416681.1
ENST00000331803.4 ENST00000432131.1 |
UPP1
|
uridine phosphorylase 1 |
| chr7_+_48128316 | 9.58 |
ENST00000341253.4
|
UPP1
|
uridine phosphorylase 1 |
| chr1_-_205419053 | 8.72 |
ENST00000367154.1
|
LEMD1
|
LEM domain containing 1 |
| chr17_+_74381343 | 8.58 |
ENST00000392496.3
|
SPHK1
|
sphingosine kinase 1 |
| chr1_-_153521714 | 8.47 |
ENST00000368713.3
|
S100A3
|
S100 calcium binding protein A3 |
| chr11_-_65667884 | 8.40 |
ENST00000448083.2
ENST00000531493.1 ENST00000532401.1 |
FOSL1
|
FOS-like antigen 1 |
| chr9_+_35673853 | 8.26 |
ENST00000378357.4
|
CA9
|
carbonic anhydrase IX |
| chr11_-_62323702 | 7.58 |
ENST00000530285.1
|
AHNAK
|
AHNAK nucleoprotein |
| chr16_+_50300427 | 7.24 |
ENST00000394697.2
ENST00000566433.2 ENST00000538642.1 |
ADCY7
|
adenylate cyclase 7 |
| chr11_-_6341724 | 6.90 |
ENST00000530979.1
|
PRKCDBP
|
protein kinase C, delta binding protein |
| chr20_+_33759854 | 6.66 |
ENST00000216968.4
|
PROCR
|
protein C receptor, endothelial |
| chr11_+_35198243 | 6.65 |
ENST00000528455.1
|
CD44
|
CD44 molecule (Indian blood group) |
| chr6_+_74405804 | 6.65 |
ENST00000287097.5
|
CD109
|
CD109 molecule |
| chr6_+_74405501 | 6.62 |
ENST00000437994.2
ENST00000422508.2 |
CD109
|
CD109 molecule |
| chr11_-_102668879 | 6.61 |
ENST00000315274.6
|
MMP1
|
matrix metallopeptidase 1 (interstitial collagenase) |
| chr12_-_48152853 | 6.39 |
ENST00000171000.4
|
RAPGEF3
|
Rap guanine nucleotide exchange factor (GEF) 3 |
| chr4_-_39033963 | 6.36 |
ENST00000381938.3
|
TMEM156
|
transmembrane protein 156 |
| chr12_-_48152611 | 6.09 |
ENST00000389212.3
|
RAPGEF3
|
Rap guanine nucleotide exchange factor (GEF) 3 |
| chr3_-_48632593 | 6.00 |
ENST00000454817.1
ENST00000328333.8 |
COL7A1
|
collagen, type VII, alpha 1 |
| chr11_-_66104237 | 5.99 |
ENST00000530056.1
|
RIN1
|
Ras and Rab interactor 1 |
| chr19_-_35992780 | 5.90 |
ENST00000593342.1
ENST00000601650.1 ENST00000408915.2 |
DMKN
|
dermokine |
| chr19_-_51523412 | 5.84 |
ENST00000391805.1
ENST00000599077.1 |
KLK10
|
kallikrein-related peptidase 10 |
| chr1_-_28520384 | 5.80 |
ENST00000305392.3
|
PTAFR
|
platelet-activating factor receptor |
| chr19_-_51538118 | 5.73 |
ENST00000529888.1
|
KLK12
|
kallikrein-related peptidase 12 |
| chr7_-_107643674 | 5.72 |
ENST00000222399.6
|
LAMB1
|
laminin, beta 1 |
| chr12_-_54813229 | 5.65 |
ENST00000293379.4
|
ITGA5
|
integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| chr1_-_28520447 | 5.63 |
ENST00000539896.1
|
PTAFR
|
platelet-activating factor receptor |
| chr12_-_95009837 | 5.62 |
ENST00000551457.1
|
TMCC3
|
transmembrane and coiled-coil domain family 3 |
| chr18_+_61442629 | 5.62 |
ENST00000398019.2
ENST00000540675.1 |
SERPINB7
|
serpin peptidase inhibitor, clade B (ovalbumin), member 7 |
| chr19_-_44285401 | 5.55 |
ENST00000262888.3
|
KCNN4
|
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 |
| chr19_-_51538148 | 5.55 |
ENST00000319590.4
ENST00000250351.4 |
KLK12
|
kallikrein-related peptidase 12 |
| chr11_-_6341844 | 5.51 |
ENST00000303927.3
|
PRKCDBP
|
protein kinase C, delta binding protein |
| chr19_-_36004543 | 5.39 |
ENST00000339686.3
ENST00000447113.2 ENST00000440396.1 |
DMKN
|
dermokine |
| chr1_-_150208320 | 5.26 |
ENST00000534220.1
|
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chr1_-_154943212 | 5.26 |
ENST00000368445.5
ENST00000448116.2 ENST00000368449.4 |
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1 |
| chr6_+_106546808 | 5.23 |
ENST00000369089.3
|
PRDM1
|
PR domain containing 1, with ZNF domain |
| chr12_-_122238464 | 5.17 |
ENST00000546227.1
|
RHOF
|
ras homolog family member F (in filopodia) |
| chr1_-_204121013 | 5.10 |
ENST00000367201.3
|
ETNK2
|
ethanolamine kinase 2 |
| chr1_-_162381907 | 4.97 |
ENST00000367929.2
ENST00000359567.3 |
SH2D1B
|
SH2 domain containing 1B |
| chr1_-_154943002 | 4.96 |
ENST00000606391.1
|
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1 |
| chr1_-_204121102 | 4.89 |
ENST00000367202.4
|
ETNK2
|
ethanolamine kinase 2 |
| chr4_-_39034542 | 4.88 |
ENST00000344606.6
|
TMEM156
|
transmembrane protein 156 |
| chr11_-_66103932 | 4.81 |
ENST00000311320.4
|
RIN1
|
Ras and Rab interactor 1 |
| chr1_-_204121298 | 4.78 |
ENST00000367199.2
|
ETNK2
|
ethanolamine kinase 2 |
| chr19_-_51523275 | 4.78 |
ENST00000309958.3
|
KLK10
|
kallikrein-related peptidase 10 |
| chr10_-_90611566 | 4.71 |
ENST00000371930.4
|
ANKRD22
|
ankyrin repeat domain 22 |
| chr17_+_4853442 | 4.68 |
ENST00000522301.1
|
ENO3
|
enolase 3 (beta, muscle) |
| chr1_+_153003671 | 4.62 |
ENST00000307098.4
|
SPRR1B
|
small proline-rich protein 1B |
| chr9_+_140119618 | 4.59 |
ENST00000359069.2
|
C9orf169
|
chromosome 9 open reading frame 169 |
| chr12_-_95510743 | 4.46 |
ENST00000551521.1
|
FGD6
|
FYVE, RhoGEF and PH domain containing 6 |
| chr1_-_95007193 | 4.22 |
ENST00000370207.4
ENST00000334047.7 |
F3
|
coagulation factor III (thromboplastin, tissue factor) |
| chr11_-_66103867 | 4.22 |
ENST00000424433.2
|
RIN1
|
Ras and Rab interactor 1 |
| chr11_-_102826434 | 4.11 |
ENST00000340273.4
ENST00000260302.3 |
MMP13
|
matrix metallopeptidase 13 (collagenase 3) |
| chr4_+_84457250 | 4.00 |
ENST00000395226.2
|
AGPAT9
|
1-acylglycerol-3-phosphate O-acyltransferase 9 |
| chr11_+_394196 | 3.98 |
ENST00000331563.2
ENST00000531857.1 |
PKP3
|
plakophilin 3 |
| chr11_+_35198118 | 3.95 |
ENST00000525211.1
ENST00000526000.1 ENST00000279452.6 ENST00000527889.1 |
CD44
|
CD44 molecule (Indian blood group) |
| chr11_+_12308447 | 3.92 |
ENST00000256186.2
|
MICALCL
|
MICAL C-terminal like |
| chr17_-_39780819 | 3.87 |
ENST00000311208.8
|
KRT17
|
keratin 17 |
| chr2_+_191792376 | 3.78 |
ENST00000409428.1
ENST00000409215.1 |
GLS
|
glutaminase |
| chr1_+_24645865 | 3.72 |
ENST00000342072.4
|
GRHL3
|
grainyhead-like 3 (Drosophila) |
| chr4_+_84457529 | 3.70 |
ENST00000264409.4
|
AGPAT9
|
1-acylglycerol-3-phosphate O-acyltransferase 9 |
| chr1_+_24645807 | 3.66 |
ENST00000361548.4
|
GRHL3
|
grainyhead-like 3 (Drosophila) |
| chr5_+_149877334 | 3.65 |
ENST00000523767.1
|
NDST1
|
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| chr16_-_28518153 | 3.65 |
ENST00000356897.1
|
IL27
|
interleukin 27 |
| chr2_+_220492373 | 3.64 |
ENST00000317151.3
|
SLC4A3
|
solute carrier family 4 (anion exchanger), member 3 |
| chrX_+_99899180 | 3.63 |
ENST00000373004.3
|
SRPX2
|
sushi-repeat containing protein, X-linked 2 |
| chr1_+_24646002 | 3.63 |
ENST00000356046.2
|
GRHL3
|
grainyhead-like 3 (Drosophila) |
| chr17_-_33390667 | 3.43 |
ENST00000378516.2
ENST00000268850.7 ENST00000394597.2 |
RFFL
|
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase |
| chr18_+_61554932 | 3.34 |
ENST00000299502.4
ENST00000457692.1 ENST00000413956.1 |
SERPINB2
|
serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| chr1_-_151965048 | 3.32 |
ENST00000368809.1
|
S100A10
|
S100 calcium binding protein A10 |
| chr2_-_65593784 | 3.31 |
ENST00000443619.2
|
SPRED2
|
sprouty-related, EVH1 domain containing 2 |
| chr9_+_4985016 | 3.29 |
ENST00000539801.1
|
JAK2
|
Janus kinase 2 |
| chr14_+_103801140 | 3.21 |
ENST00000561325.1
ENST00000392715.2 ENST00000559130.1 ENST00000559532.1 ENST00000558506.1 |
EIF5
|
eukaryotic translation initiation factor 5 |
| chr6_+_41604747 | 3.21 |
ENST00000419164.1
ENST00000373051.2 |
MDFI
|
MyoD family inhibitor |
| chr11_-_2924720 | 3.19 |
ENST00000455942.2
|
SLC22A18AS
|
solute carrier family 22 (organic cation transporter), member 18 antisense |
| chr17_-_18908040 | 3.19 |
ENST00000388995.6
|
FAM83G
|
family with sequence similarity 83, member G |
| chr9_-_35112376 | 3.18 |
ENST00000488109.2
|
FAM214B
|
family with sequence similarity 214, member B |
| chr16_-_30125177 | 3.18 |
ENST00000406256.3
|
GDPD3
|
glycerophosphodiester phosphodiesterase domain containing 3 |
| chr2_+_33359687 | 3.14 |
ENST00000402934.1
ENST00000404525.1 ENST00000407925.1 |
LTBP1
|
latent transforming growth factor beta binding protein 1 |
| chr11_-_2924970 | 3.13 |
ENST00000533594.1
|
SLC22A18AS
|
solute carrier family 22 (organic cation transporter), member 18 antisense |
| chr1_-_150208291 | 3.13 |
ENST00000533654.1
|
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chr15_-_70388599 | 3.10 |
ENST00000560996.1
ENST00000558201.1 |
TLE3
|
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) |
| chr15_-_70388943 | 3.07 |
ENST00000559048.1
ENST00000560939.1 ENST00000440567.3 ENST00000557907.1 ENST00000558379.1 ENST00000451782.2 ENST00000559929.1 |
TLE3
|
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) |
| chr7_+_55177416 | 3.05 |
ENST00000450046.1
ENST00000454757.2 |
EGFR
|
epidermal growth factor receptor |
| chr16_+_58533951 | 3.04 |
ENST00000566192.1
ENST00000565088.1 ENST00000568640.1 ENST00000563978.1 ENST00000569923.1 ENST00000356752.4 ENST00000563799.1 ENST00000562999.1 ENST00000570248.1 ENST00000562731.1 ENST00000568424.1 |
NDRG4
|
NDRG family member 4 |
| chr3_-_98241358 | 3.03 |
ENST00000503004.1
ENST00000506575.1 ENST00000513452.1 ENST00000515620.1 |
CLDND1
|
claudin domain containing 1 |
| chr6_+_106534192 | 2.99 |
ENST00000369091.2
ENST00000369096.4 |
PRDM1
|
PR domain containing 1, with ZNF domain |
| chr2_-_85641162 | 2.99 |
ENST00000447219.2
ENST00000409670.1 ENST00000409724.1 |
CAPG
|
capping protein (actin filament), gelsolin-like |
| chr1_-_150208363 | 2.99 |
ENST00000436748.2
|
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chr2_+_33359646 | 2.96 |
ENST00000390003.4
ENST00000418533.2 |
LTBP1
|
latent transforming growth factor beta binding protein 1 |
| chr3_-_151034734 | 2.96 |
ENST00000260843.4
|
GPR87
|
G protein-coupled receptor 87 |
| chr4_-_987217 | 2.96 |
ENST00000361661.2
ENST00000398516.2 |
SLC26A1
|
solute carrier family 26 (anion exchanger), member 1 |
| chr17_-_45928521 | 2.91 |
ENST00000536300.1
|
SP6
|
Sp6 transcription factor |
| chr14_+_96722539 | 2.89 |
ENST00000553356.1
|
BDKRB1
|
bradykinin receptor B1 |
| chr19_+_39279838 | 2.88 |
ENST00000314980.4
|
LGALS7B
|
lectin, galactoside-binding, soluble, 7B |
| chr17_-_9694614 | 2.87 |
ENST00000330255.5
ENST00000571134.1 |
DHRS7C
|
dehydrogenase/reductase (SDR family) member 7C |
| chr12_-_53625958 | 2.84 |
ENST00000327550.3
ENST00000546717.1 ENST00000425354.2 ENST00000394426.1 |
RARG
|
retinoic acid receptor, gamma |
| chr14_+_96722152 | 2.84 |
ENST00000216629.6
|
BDKRB1
|
bradykinin receptor B1 |
| chr5_-_140013275 | 2.83 |
ENST00000512545.1
ENST00000302014.6 ENST00000401743.2 |
CD14
|
CD14 molecule |
| chr1_+_26605618 | 2.75 |
ENST00000270792.5
|
SH3BGRL3
|
SH3 domain binding glutamic acid-rich protein like 3 |
| chr9_-_35111570 | 2.73 |
ENST00000378561.1
ENST00000603301.1 |
FAM214B
|
family with sequence similarity 214, member B |
| chr11_+_706219 | 2.72 |
ENST00000533500.1
|
EPS8L2
|
EPS8-like 2 |
| chr1_+_155006300 | 2.70 |
ENST00000295542.1
ENST00000392480.1 ENST00000423025.2 ENST00000368419.2 |
DCST1
|
DC-STAMP domain containing 1 |
| chr9_+_124329336 | 2.66 |
ENST00000394340.3
ENST00000436835.1 ENST00000259371.2 |
DAB2IP
|
DAB2 interacting protein |
| chr13_+_32838801 | 2.66 |
ENST00000542859.1
|
FRY
|
furry homolog (Drosophila) |
| chr9_+_4985228 | 2.63 |
ENST00000381652.3
|
JAK2
|
Janus kinase 2 |
| chr11_-_82708519 | 2.62 |
ENST00000534301.1
|
RAB30
|
RAB30, member RAS oncogene family |
| chr2_+_28615669 | 2.61 |
ENST00000379619.1
ENST00000264716.4 |
FOSL2
|
FOS-like antigen 2 |
| chr8_+_126442563 | 2.57 |
ENST00000311922.3
|
TRIB1
|
tribbles pseudokinase 1 |
| chr3_-_37216055 | 2.57 |
ENST00000336686.4
|
LRRFIP2
|
leucine rich repeat (in FLII) interacting protein 2 |
| chr3_-_149095652 | 2.56 |
ENST00000305366.3
|
TM4SF1
|
transmembrane 4 L six family member 1 |
| chr8_-_42623747 | 2.56 |
ENST00000534622.1
|
CHRNA6
|
cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| chr10_-_76868931 | 2.54 |
ENST00000372700.3
ENST00000473072.2 ENST00000491677.2 ENST00000607131.1 ENST00000372702.3 |
DUSP13
|
dual specificity phosphatase 13 |
| chr9_-_130341268 | 2.53 |
ENST00000373314.3
|
FAM129B
|
family with sequence similarity 129, member B |
| chr17_+_73717407 | 2.52 |
ENST00000579662.1
|
ITGB4
|
integrin, beta 4 |
| chr9_-_35111420 | 2.52 |
ENST00000378557.1
|
FAM214B
|
family with sequence similarity 214, member B |
| chr6_+_32121218 | 2.52 |
ENST00000414204.1
ENST00000361568.2 ENST00000395523.1 |
PPT2
|
palmitoyl-protein thioesterase 2 |
| chr7_+_128095945 | 2.42 |
ENST00000257696.4
|
HILPDA
|
hypoxia inducible lipid droplet-associated |
| chr15_+_40531243 | 2.42 |
ENST00000558055.1
ENST00000455577.2 |
PAK6
|
p21 protein (Cdc42/Rac)-activated kinase 6 |
| chr16_+_83986827 | 2.34 |
ENST00000393306.1
ENST00000565123.1 |
OSGIN1
|
oxidative stress induced growth inhibitor 1 |
| chr15_+_44829334 | 2.34 |
ENST00000535391.1
|
EIF3J
|
eukaryotic translation initiation factor 3, subunit J |
| chr17_-_39743139 | 2.29 |
ENST00000167586.6
|
KRT14
|
keratin 14 |
| chr7_+_128095900 | 2.28 |
ENST00000435296.2
|
HILPDA
|
hypoxia inducible lipid droplet-associated |
| chr1_+_26606608 | 2.27 |
ENST00000319041.6
|
SH3BGRL3
|
SH3 domain binding glutamic acid-rich protein like 3 |
| chr16_-_2908155 | 2.26 |
ENST00000571228.1
ENST00000161006.3 |
PRSS22
|
protease, serine, 22 |
| chr8_-_42623924 | 2.26 |
ENST00000276410.2
|
CHRNA6
|
cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| chr13_-_103719196 | 2.25 |
ENST00000245312.3
|
SLC10A2
|
solute carrier family 10 (sodium/bile acid cotransporter), member 2 |
| chr2_-_18770812 | 2.24 |
ENST00000359846.2
ENST00000304081.4 ENST00000600945.1 ENST00000532967.1 ENST00000444297.2 |
NT5C1B
NT5C1B-RDH14
|
5'-nucleotidase, cytosolic IB NT5C1B-RDH14 readthrough |
| chr15_-_56209306 | 2.23 |
ENST00000506154.1
ENST00000338963.2 ENST00000508342.1 |
NEDD4
|
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| chr17_-_43502987 | 2.21 |
ENST00000376922.2
|
ARHGAP27
|
Rho GTPase activating protein 27 |
| chr11_+_706113 | 2.21 |
ENST00000318562.8
ENST00000533256.1 ENST00000534755.1 |
EPS8L2
|
EPS8-like 2 |
| chr11_+_57308979 | 2.21 |
ENST00000457912.1
|
SMTNL1
|
smoothelin-like 1 |
| chr8_-_125384927 | 2.21 |
ENST00000297632.6
|
TMEM65
|
transmembrane protein 65 |
| chr17_-_27045405 | 2.21 |
ENST00000430132.2
|
RAB34
|
RAB34, member RAS oncogene family |
| chr17_+_73717551 | 2.20 |
ENST00000450894.3
|
ITGB4
|
integrin, beta 4 |
| chr7_+_134528635 | 2.20 |
ENST00000445569.2
|
CALD1
|
caldesmon 1 |
| chr4_-_80329356 | 2.18 |
ENST00000358842.3
|
GK2
|
glycerol kinase 2 |
| chr18_+_61143994 | 2.13 |
ENST00000382771.4
|
SERPINB5
|
serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| chr15_+_89182178 | 2.12 |
ENST00000559876.1
|
ISG20
|
interferon stimulated exonuclease gene 20kDa |
| chr15_-_70994612 | 2.10 |
ENST00000558758.1
ENST00000379983.2 ENST00000560441.1 |
UACA
|
uveal autoantigen with coiled-coil domains and ankyrin repeats |
| chr19_-_6670128 | 2.08 |
ENST00000245912.3
|
TNFSF14
|
tumor necrosis factor (ligand) superfamily, member 14 |
| chr1_-_155947951 | 2.06 |
ENST00000313695.7
ENST00000497907.1 |
ARHGEF2
|
Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| chr10_+_49892904 | 2.03 |
ENST00000360890.2
|
WDFY4
|
WDFY family member 4 |
| chr3_+_57094469 | 2.00 |
ENST00000334325.1
|
SPATA12
|
spermatogenesis associated 12 |
| chr11_-_111783919 | 1.98 |
ENST00000531198.1
ENST00000533879.1 |
CRYAB
|
crystallin, alpha B |
| chr18_+_52495426 | 1.97 |
ENST00000262094.5
|
RAB27B
|
RAB27B, member RAS oncogene family |
| chr14_+_94492674 | 1.95 |
ENST00000203664.5
ENST00000553723.1 |
OTUB2
|
OTU domain, ubiquitin aldehyde binding 2 |
| chr15_+_40531621 | 1.94 |
ENST00000560346.1
|
PAK6
|
p21 protein (Cdc42/Rac)-activated kinase 6 |
| chr2_+_202316392 | 1.93 |
ENST00000194530.3
ENST00000392249.2 |
STRADB
|
STE20-related kinase adaptor beta |
| chr1_+_156095951 | 1.91 |
ENST00000448611.2
ENST00000368297.1 |
LMNA
|
lamin A/C |
| chr6_-_84140757 | 1.91 |
ENST00000541327.1
ENST00000369705.3 ENST00000543031.1 |
ME1
|
malic enzyme 1, NADP(+)-dependent, cytosolic |
| chr6_-_35888824 | 1.90 |
ENST00000361690.3
ENST00000512445.1 |
SRPK1
|
SRSF protein kinase 1 |
| chr12_-_57914275 | 1.89 |
ENST00000547303.1
ENST00000552740.1 ENST00000547526.1 ENST00000551116.1 ENST00000346473.3 |
DDIT3
|
DNA-damage-inducible transcript 3 |
| chr10_+_30722866 | 1.88 |
ENST00000263056.1
|
MAP3K8
|
mitogen-activated protein kinase kinase kinase 8 |
| chr2_-_165697920 | 1.88 |
ENST00000342193.4
ENST00000375458.2 |
COBLL1
|
cordon-bleu WH2 repeat protein-like 1 |
| chr16_+_81678957 | 1.87 |
ENST00000398040.4
|
CMIP
|
c-Maf inducing protein |
| chr17_-_27503770 | 1.86 |
ENST00000533112.1
|
MYO18A
|
myosin XVIIIA |
| chr1_-_150208412 | 1.83 |
ENST00000532744.1
ENST00000369114.5 ENST00000369115.2 ENST00000369116.4 |
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chr2_+_87808725 | 1.83 |
ENST00000413202.1
|
LINC00152
|
long intergenic non-protein coding RNA 152 |
| chr7_-_42276612 | 1.83 |
ENST00000395925.3
ENST00000437480.1 |
GLI3
|
GLI family zinc finger 3 |
| chr6_-_35888905 | 1.81 |
ENST00000510290.1
ENST00000423325.2 ENST00000373822.1 |
SRPK1
|
SRSF protein kinase 1 |
| chr17_-_27045427 | 1.80 |
ENST00000301043.6
ENST00000412625.1 |
RAB34
|
RAB34, member RAS oncogene family |
| chr19_+_17865011 | 1.79 |
ENST00000596462.1
ENST00000596865.1 ENST00000598960.1 ENST00000539407.1 |
FCHO1
|
FCH domain only 1 |
| chr4_+_74606223 | 1.79 |
ENST00000307407.3
ENST00000401931.1 |
IL8
|
interleukin 8 |
| chr9_-_127177703 | 1.77 |
ENST00000259457.3
ENST00000536392.1 ENST00000441097.1 |
PSMB7
|
proteasome (prosome, macropain) subunit, beta type, 7 |
| chr14_-_75643296 | 1.77 |
ENST00000303575.4
|
TMED10
|
transmembrane emp24-like trafficking protein 10 (yeast) |
| chr1_-_179112173 | 1.77 |
ENST00000408940.3
ENST00000504405.1 |
ABL2
|
c-abl oncogene 2, non-receptor tyrosine kinase |
| chr11_+_35639735 | 1.73 |
ENST00000317811.4
|
FJX1
|
four jointed box 1 (Drosophila) |
| chr11_-_47207390 | 1.68 |
ENST00000539589.1
ENST00000528462.1 |
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3 |
| chr11_+_128563948 | 1.67 |
ENST00000534087.2
|
FLI1
|
Fli-1 proto-oncogene, ETS transcription factor |
| chr1_+_62417957 | 1.64 |
ENST00000307297.7
ENST00000543708.1 |
INADL
|
InaD-like (Drosophila) |
| chr5_+_145317356 | 1.63 |
ENST00000511217.1
|
SH3RF2
|
SH3 domain containing ring finger 2 |
| chr6_-_49755019 | 1.62 |
ENST00000304801.3
|
PGK2
|
phosphoglycerate kinase 2 |
| chr6_+_106959718 | 1.61 |
ENST00000369066.3
|
AIM1
|
absent in melanoma 1 |
| chr2_+_169926047 | 1.60 |
ENST00000428522.1
ENST00000450153.1 ENST00000421653.1 |
DHRS9
|
dehydrogenase/reductase (SDR family) member 9 |
| chr12_-_10324716 | 1.59 |
ENST00000545927.1
ENST00000432556.2 ENST00000309539.3 ENST00000544577.1 |
OLR1
|
oxidized low density lipoprotein (lectin-like) receptor 1 |
| chrX_-_15511438 | 1.57 |
ENST00000380420.5
|
PIR
|
pirin (iron-binding nuclear protein) |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOSL1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.4 | 25.3 | GO:0046586 | regulation of calcium-dependent cell-cell adhesion(GO:0046586) |
| 4.8 | 19.2 | GO:0006218 | uridine catabolic process(GO:0006218) |
| 3.9 | 11.7 | GO:0018153 | isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262) |
| 3.8 | 11.4 | GO:0071258 | positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317) |
| 3.1 | 12.5 | GO:0030807 | positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123) |
| 3.1 | 18.4 | GO:0007296 | vitellogenesis(GO:0007296) |
| 2.9 | 8.6 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
| 2.2 | 13.3 | GO:0072674 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 1.9 | 11.3 | GO:1903575 | cornified envelope assembly(GO:1903575) |
| 1.9 | 54.5 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 1.9 | 15.0 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 1.6 | 8.2 | GO:0033078 | extrathymic T cell differentiation(GO:0033078) |
| 1.4 | 5.7 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 1.4 | 4.2 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 1.4 | 5.6 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 1.4 | 36.3 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 1.4 | 6.8 | GO:0031959 | mineralocorticoid receptor signaling pathway(GO:0031959) |
| 1.3 | 10.6 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 1.2 | 4.7 | GO:0035425 | autocrine signaling(GO:0035425) |
| 1.0 | 5.0 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.9 | 11.0 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
| 0.9 | 7.9 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.9 | 2.6 | GO:0045658 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 0.8 | 2.5 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.8 | 2.5 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 0.8 | 14.0 | GO:0051546 | keratinocyte migration(GO:0051546) |
| 0.8 | 3.9 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 0.8 | 54.6 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.8 | 3.0 | GO:0043006 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) |
| 0.8 | 3.8 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.7 | 2.2 | GO:0046167 | glycerol-3-phosphate biosynthetic process(GO:0046167) |
| 0.7 | 2.8 | GO:0070384 | Harderian gland development(GO:0070384) |
| 0.7 | 2.8 | GO:0071725 | toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727) |
| 0.7 | 3.4 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 0.6 | 1.9 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 0.6 | 11.0 | GO:0090179 | planar cell polarity pathway involved in neural tube closure(GO:0090179) |
| 0.6 | 6.1 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.5 | 14.8 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.5 | 4.9 | GO:0030948 | negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) |
| 0.5 | 8.0 | GO:0044351 | macropinocytosis(GO:0044351) phagosome-lysosome fusion(GO:0090385) |
| 0.5 | 13.7 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.5 | 1.6 | GO:0060720 | spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723) |
| 0.5 | 2.4 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 0.5 | 3.7 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 0.5 | 1.8 | GO:0021798 | forebrain dorsal/ventral pattern formation(GO:0021798) mammary gland specification(GO:0060594) |
| 0.4 | 1.8 | GO:0048205 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.4 | 3.5 | GO:0034036 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 0.4 | 5.0 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.4 | 2.1 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 0.4 | 2.1 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.4 | 1.6 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.4 | 5.6 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
| 0.4 | 1.9 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) regulation of determination of dorsal identity(GO:2000015) |
| 0.4 | 3.7 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.4 | 6.2 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 0.3 | 2.1 | GO:0030421 | defecation(GO:0030421) |
| 0.3 | 2.7 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
| 0.3 | 3.6 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.3 | 7.2 | GO:0071361 | cellular response to ethanol(GO:0071361) |
| 0.3 | 2.6 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
| 0.3 | 1.0 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 0.3 | 1.3 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 0.3 | 0.9 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.3 | 0.9 | GO:1902938 | regulation of intracellular calcium activated chloride channel activity(GO:1902938) |
| 0.3 | 1.5 | GO:0010481 | epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) |
| 0.3 | 1.2 | GO:0038195 | urokinase plasminogen activator signaling pathway(GO:0038195) |
| 0.3 | 14.4 | GO:0043486 | histone exchange(GO:0043486) |
| 0.3 | 1.4 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
| 0.3 | 3.9 | GO:0051798 | positive regulation of hair follicle development(GO:0051798) |
| 0.3 | 4.9 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.3 | 1.9 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 0.3 | 0.8 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 0.3 | 3.7 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.3 | 3.6 | GO:0045625 | regulation of T-helper 1 cell differentiation(GO:0045625) |
| 0.3 | 11.1 | GO:0007176 | regulation of epidermal growth factor-activated receptor activity(GO:0007176) |
| 0.3 | 2.5 | GO:0098734 | macromolecule depalmitoylation(GO:0098734) |
| 0.2 | 1.4 | GO:0038124 | toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) |
| 0.2 | 3.0 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
| 0.2 | 0.6 | GO:1904730 | negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730) |
| 0.2 | 3.2 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 0.2 | 0.4 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.2 | 3.3 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.2 | 2.1 | GO:1901222 | regulation of NIK/NF-kappaB signaling(GO:1901222) |
| 0.2 | 1.1 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 0.2 | 0.5 | GO:0033693 | neurofilament bundle assembly(GO:0033693) |
| 0.2 | 8.5 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.2 | 0.7 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.2 | 0.5 | GO:2000854 | positive regulation of corticosterone secretion(GO:2000854) |
| 0.2 | 3.5 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.2 | 4.3 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.2 | 3.0 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.1 | 2.7 | GO:0001765 | membrane raft assembly(GO:0001765) |
| 0.1 | 1.9 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.1 | 1.6 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.1 | 0.7 | GO:0032455 | nerve growth factor processing(GO:0032455) |
| 0.1 | 1.9 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.1 | 9.3 | GO:0033574 | response to testosterone(GO:0033574) |
| 0.1 | 0.6 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
| 0.1 | 3.0 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.1 | 1.7 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.1 | 5.7 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.1 | 5.0 | GO:0014059 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.1 | 0.9 | GO:0010626 | regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) |
| 0.1 | 7.2 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.1 | 2.9 | GO:0070498 | interleukin-1-mediated signaling pathway(GO:0070498) |
| 0.1 | 10.0 | GO:0050819 | negative regulation of coagulation(GO:0050819) |
| 0.1 | 3.9 | GO:0042481 | regulation of odontogenesis(GO:0042481) |
| 0.1 | 0.7 | GO:0060125 | negative regulation of growth hormone secretion(GO:0060125) |
| 0.1 | 0.5 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.1 | 2.9 | GO:0002717 | positive regulation of natural killer cell mediated immunity(GO:0002717) |
| 0.1 | 6.2 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.1 | 0.5 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.1 | 0.3 | GO:1901656 | glycoside transport(GO:1901656) |
| 0.1 | 0.4 | GO:0002268 | follicular dendritic cell differentiation(GO:0002268) |
| 0.1 | 2.7 | GO:0060512 | prostate gland morphogenesis(GO:0060512) |
| 0.1 | 2.0 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.1 | 9.6 | GO:0070268 | cornification(GO:0070268) |
| 0.1 | 0.2 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
| 0.1 | 9.9 | GO:0002062 | chondrocyte differentiation(GO:0002062) |
| 0.1 | 0.4 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
| 0.1 | 3.9 | GO:0035987 | endodermal cell differentiation(GO:0035987) |
| 0.1 | 1.2 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.1 | 3.7 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.1 | 11.1 | GO:0030216 | keratinocyte differentiation(GO:0030216) |
| 0.1 | 0.6 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.1 | 5.8 | GO:0030834 | regulation of actin filament depolymerization(GO:0030834) |
| 0.1 | 2.6 | GO:0032461 | positive regulation of protein oligomerization(GO:0032461) |
| 0.1 | 0.1 | GO:0060763 | mammary duct terminal end bud growth(GO:0060763) |
| 0.1 | 0.4 | GO:0097324 | melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748) |
| 0.1 | 1.2 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
| 0.1 | 1.2 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.1 | 0.2 | GO:0042636 | negative regulation of hair cycle(GO:0042636) |
| 0.1 | 0.5 | GO:0035973 | aggrephagy(GO:0035973) |
| 0.1 | 1.4 | GO:0051412 | response to corticosterone(GO:0051412) |
| 0.1 | 1.7 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.1 | 0.1 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 0.1 | 0.6 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 3.8 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.1 | 0.8 | GO:1903541 | regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543) |
| 0.1 | 0.7 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 0.0 | GO:0035793 | positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591) |
| 0.0 | 0.4 | GO:2000576 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.0 | 0.2 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 0.0 | 1.4 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.0 | 1.6 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.0 | 0.9 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.0 | 0.5 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.0 | 1.6 | GO:0030224 | monocyte differentiation(GO:0030224) |
| 0.0 | 0.6 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.0 | 1.1 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
| 0.0 | 0.6 | GO:0045604 | regulation of epidermal cell differentiation(GO:0045604) |
| 0.0 | 0.1 | GO:0038178 | complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623) |
| 0.0 | 1.4 | GO:0006693 | prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693) |
| 0.0 | 1.0 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.0 | 1.8 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.0 | 0.7 | GO:0007605 | sensory perception of sound(GO:0007605) |
| 0.0 | 0.2 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.0 | 1.4 | GO:0010880 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) |
| 0.0 | 0.2 | GO:1990182 | exosomal secretion(GO:1990182) |
| 0.0 | 1.2 | GO:0034629 | cellular protein complex localization(GO:0034629) |
| 0.0 | 0.3 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) |
| 0.0 | 0.8 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.0 | 1.0 | GO:0021983 | pituitary gland development(GO:0021983) |
| 0.0 | 0.1 | GO:0071651 | positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651) |
| 0.0 | 1.3 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
| 0.0 | 0.1 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
| 0.0 | 2.2 | GO:0003231 | cardiac ventricle development(GO:0003231) |
| 0.0 | 0.5 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.6 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.0 | 0.7 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.0 | 3.2 | GO:0030509 | BMP signaling pathway(GO:0030509) |
| 0.0 | 0.7 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 1.9 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.0 | 1.3 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.4 | GO:1902652 | cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652) |
| 0.0 | 1.3 | GO:0000226 | microtubule cytoskeleton organization(GO:0000226) |
| 0.0 | 2.0 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.0 | 0.1 | GO:1904383 | response to sodium phosphate(GO:1904383) |
| 0.0 | 1.6 | GO:0006757 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
| 0.0 | 1.0 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.0 | 0.2 | GO:0051964 | netrin-activated signaling pathway(GO:0038007) negative regulation of synapse assembly(GO:0051964) |
| 0.0 | 1.2 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.9 | GO:0007602 | phototransduction(GO:0007602) |
| 0.0 | 0.6 | GO:0042058 | regulation of epidermal growth factor receptor signaling pathway(GO:0042058) |
| 0.0 | 1.0 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 0.2 | GO:0045907 | positive regulation of vasoconstriction(GO:0045907) |
| 0.0 | 0.1 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.0 | 0.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.1 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.0 | 0.1 | GO:0050710 | negative regulation of cytokine secretion(GO:0050710) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.5 | 19.5 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 4.0 | 32.3 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 2.2 | 13.3 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 2.0 | 36.3 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 1.5 | 10.6 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 1.5 | 6.0 | GO:0030934 | anchoring collagen complex(GO:0030934) |
| 1.5 | 96.0 | GO:0001533 | cornified envelope(GO:0001533) |
| 1.4 | 5.6 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 1.0 | 7.1 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.9 | 2.7 | GO:1990032 | parallel fiber(GO:1990032) |
| 0.7 | 14.4 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.6 | 1.9 | GO:1990622 | CHOP-ATF3 complex(GO:1990622) |
| 0.6 | 2.8 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.5 | 2.9 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.4 | 14.7 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.4 | 1.3 | GO:0071159 | NF-kappaB complex(GO:0071159) |
| 0.3 | 0.8 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 0.3 | 4.9 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.3 | 2.4 | GO:0005638 | lamin filament(GO:0005638) |
| 0.3 | 7.2 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.3 | 7.6 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.2 | 6.1 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.2 | 4.8 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.2 | 0.9 | GO:1990812 | growth cone filopodium(GO:1990812) |
| 0.2 | 3.7 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.2 | 8.3 | GO:0043034 | costamere(GO:0043034) |
| 0.2 | 30.6 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.2 | 4.8 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.2 | 5.1 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.2 | 3.0 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.2 | 1.3 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.2 | 1.1 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.2 | 13.3 | GO:0005902 | microvillus(GO:0005902) |
| 0.1 | 1.6 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.1 | 2.2 | GO:0030478 | actin cap(GO:0030478) |
| 0.1 | 16.4 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 1.6 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.1 | 1.2 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.1 | 0.8 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.1 | 1.8 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 0.1 | 2.7 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.1 | 13.1 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.1 | 0.8 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.1 | 0.7 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.1 | 0.4 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 0.1 | 8.7 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 1.5 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 0.5 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.1 | 2.3 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.1 | 9.4 | GO:0005604 | basement membrane(GO:0005604) |
| 0.1 | 2.8 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 1.0 | GO:0097433 | dense body(GO:0097433) |
| 0.1 | 0.5 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.1 | 3.3 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 2.2 | GO:0031430 | M band(GO:0031430) |
| 0.1 | 3.8 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.1 | 1.2 | GO:0071437 | invadopodium(GO:0071437) |
| 0.1 | 7.0 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 3.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 14.5 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.1 | 0.3 | GO:0098536 | deuterosome(GO:0098536) |
| 0.1 | 0.2 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 0.0 | 2.6 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.4 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.6 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.0 | 3.2 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 0.9 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 3.0 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 4.3 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.2 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.0 | 1.2 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 2.0 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.6 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 2.5 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 2.3 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 2.2 | GO:0044309 | dendritic spine(GO:0043197) neuron spine(GO:0044309) |
| 0.0 | 0.4 | GO:0031010 | ISWI-type complex(GO:0031010) |
| 0.0 | 6.7 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.0 | 1.3 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 0.5 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.0 | 0.1 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.0 | 4.4 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 3.4 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 2.8 | GO:0030658 | transport vesicle membrane(GO:0030658) |
| 0.0 | 0.4 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.8 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.7 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 1.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 2.7 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.7 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 1.2 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.0 | 0.7 | GO:0099572 | postsynaptic density(GO:0014069) excitatory synapse(GO:0060076) postsynaptic specialization(GO:0099572) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.3 | 34.2 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 3.8 | 19.2 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
| 3.4 | 10.3 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
| 2.3 | 11.5 | GO:0004992 | platelet activating factor receptor activity(GO:0004992) |
| 1.9 | 5.7 | GO:0004947 | bradykinin receptor activity(GO:0004947) |
| 1.9 | 13.3 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 1.9 | 13.1 | GO:1990254 | keratin filament binding(GO:1990254) |
| 1.7 | 24.8 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 1.5 | 14.8 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 1.4 | 8.6 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 1.3 | 3.9 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 1.2 | 6.1 | GO:0050436 | microfibril binding(GO:0050436) |
| 1.1 | 5.6 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 1.1 | 3.3 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 1.0 | 12.5 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 1.0 | 7.1 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.9 | 3.7 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.8 | 3.9 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.8 | 3.8 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.7 | 3.7 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.7 | 2.2 | GO:0004370 | glycerol kinase activity(GO:0004370) |
| 0.7 | 5.9 | GO:0005143 | interleukin-12 receptor binding(GO:0005143) |
| 0.6 | 1.8 | GO:0004362 | glutathione-disulfide reductase activity(GO:0004362) |
| 0.6 | 8.3 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.6 | 2.8 | GO:0016019 | peptidoglycan receptor activity(GO:0016019) |
| 0.5 | 1.6 | GO:0004618 | phosphoglycerate kinase activity(GO:0004618) |
| 0.4 | 14.1 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.4 | 26.5 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.4 | 5.0 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.4 | 4.2 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.4 | 1.9 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.4 | 1.5 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.4 | 11.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.3 | 1.9 | GO:0004471 | malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) |
| 0.3 | 1.2 | GO:0004530 | deoxyribonuclease I activity(GO:0004530) |
| 0.3 | 3.5 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.3 | 5.2 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.3 | 6.1 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.3 | 8.0 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.3 | 2.9 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.3 | 0.8 | GO:0017082 | mineralocorticoid receptor activity(GO:0017082) |
| 0.3 | 1.4 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 0.3 | 7.2 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.3 | 2.5 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.2 | 17.6 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 0.2 | 15.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.2 | 8.2 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.2 | 0.8 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.2 | 4.8 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.2 | 2.1 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.2 | 4.6 | GO:0030275 | LRR domain binding(GO:0030275) |
| 0.2 | 2.5 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.2 | 5.0 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.2 | 5.4 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.2 | 5.0 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.2 | 0.9 | GO:1903135 | cupric ion binding(GO:1903135) |
| 0.1 | 2.8 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.1 | 1.6 | GO:0047035 | testosterone dehydrogenase (NAD+) activity(GO:0047035) |
| 0.1 | 3.0 | GO:0001608 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.1 | 1.3 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.1 | 0.8 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.1 | 2.9 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.1 | 2.6 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.1 | 1.4 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.1 | 13.6 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 0.5 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.1 | 1.8 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.1 | 0.8 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.1 | 0.2 | GO:0031893 | vasopressin receptor binding(GO:0031893) |
| 0.1 | 2.2 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.1 | 1.7 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.1 | 1.7 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.1 | 2.8 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 12.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 1.6 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.1 | 1.2 | GO:0030548 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.1 | 2.6 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.1 | 3.9 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.1 | 9.4 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.1 | 23.5 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 1.0 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.1 | 2.2 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 71.0 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.1 | 1.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 0.7 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.1 | 0.7 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 0.1 | 1.4 | GO:0008200 | ion channel inhibitor activity(GO:0008200) |
| 0.1 | 1.1 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.1 | 1.9 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 1.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 2.1 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 1.8 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 0.2 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.0 | 8.4 | GO:0008201 | heparin binding(GO:0008201) |
| 0.0 | 0.2 | GO:0052836 | inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
| 0.0 | 0.2 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
| 0.0 | 1.5 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 3.2 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.0 | 1.0 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.0 | 1.4 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.7 | GO:0005165 | neurotrophin receptor binding(GO:0005165) |
| 0.0 | 1.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 1.9 | GO:0043531 | ADP binding(GO:0043531) |
| 0.0 | 2.4 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.9 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.0 | 0.6 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.0 | 0.6 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
| 0.0 | 0.2 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.0 | 0.1 | GO:0004878 | complement component C5a receptor activity(GO:0004878) |
| 0.0 | 0.4 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 3.1 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 1.2 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.1 | GO:0034648 | histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
| 0.0 | 2.5 | GO:0019838 | growth factor binding(GO:0019838) |
| 0.0 | 0.5 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.0 | 0.1 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.0 | 0.1 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.0 | 0.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.0 | 0.4 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 8.2 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 3.2 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 0.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 1.5 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.4 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 4.2 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 0.1 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.0 | 0.4 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.0 | 0.8 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 0.2 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.0 | 1.0 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 0.2 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 57.9 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.6 | 39.5 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.5 | 5.9 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.4 | 11.9 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.4 | 12.8 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.3 | 7.2 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.3 | 17.7 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.3 | 10.6 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.3 | 8.6 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.3 | 25.1 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.3 | 1.9 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.2 | 12.8 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.2 | 4.2 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.1 | 36.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 9.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 3.6 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.1 | 9.9 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 4.1 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 5.3 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 2.8 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.1 | 5.8 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.1 | 1.6 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.1 | 2.1 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.1 | 5.8 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 1.3 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 17.5 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 2.8 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 0.7 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 0.5 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 1.3 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.0 | 1.4 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 1.2 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 1.8 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 5.8 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 1.7 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.9 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 8.9 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.0 | PID FGF PATHWAY | FGF signaling pathway |
| 0.0 | 1.6 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 1.3 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 0.2 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 0.1 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 19.2 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.6 | 14.8 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.6 | 10.6 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.5 | 7.2 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.5 | 13.3 | REACTOME SHC1 EVENTS IN EGFR SIGNALING | Genes involved in SHC1 events in EGFR signaling |
| 0.4 | 50.0 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.3 | 9.9 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.3 | 5.2 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.3 | 4.8 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.3 | 12.5 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.3 | 4.4 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.3 | 9.2 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.2 | 2.2 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.2 | 5.9 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.2 | 2.8 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.2 | 8.6 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.2 | 10.6 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.2 | 4.3 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.2 | 9.3 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.2 | 1.0 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.2 | 11.4 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.1 | 2.0 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.1 | 2.3 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 4.9 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.1 | 3.8 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 4.2 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.1 | 4.5 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.1 | 3.7 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 0.9 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.1 | 6.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 1.3 | REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
| 0.1 | 3.9 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 2.7 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.1 | 1.9 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.1 | 4.5 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 5.9 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 1.1 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.1 | 1.8 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.1 | 1.1 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.1 | 3.5 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 1.9 | REACTOME SIGNALING BY FGFR1 MUTANTS | Genes involved in Signaling by FGFR1 mutants |
| 0.1 | 1.4 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.1 | 4.3 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.1 | 7.5 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.0 | 2.4 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.9 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 4.4 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 0.4 | REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX | Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex |
| 0.0 | 0.8 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 6.0 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 2.1 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.5 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 1.2 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 0.8 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 0.2 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.0 | 1.2 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 1.5 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.2 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.0 | 0.2 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.0 | 0.5 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.0 | 2.6 | REACTOME TRANSLATION | Genes involved in Translation |