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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for FOXJ2

Z-value: 0.69

Motif logo

Transcription factors associated with FOXJ2

Gene Symbol Gene ID Gene Info
ENSG00000065970.4 forkhead box J2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXJ2hg19_v2_chr12_+_8185288_81853390.383.9e-02Click!

Activity profile of FOXJ2 motif

Sorted Z-values of FOXJ2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_35201826 2.19 ENST00000531873.1
CD44 molecule (Indian blood group)
chr19_+_56989609 2.15 ENST00000601875.1
ZNF667 antisense RNA 1 (head to head)
chr3_-_122102065 2.00 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
coiled-coil domain containing 58
chr12_-_8815215 1.83 ENST00000544889.1
ENST00000543369.1
microfibrillar associated protein 5
chr1_+_45212074 1.79 ENST00000372217.1
kinesin family member 2C
chr12_-_8815299 1.75 ENST00000535336.1
microfibrillar associated protein 5
chr1_-_197115818 1.55 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr15_+_67430339 1.43 ENST00000439724.3
SMAD family member 3
chrX_+_99899180 1.34 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chrX_-_107682702 1.34 ENST00000372216.4
collagen, type IV, alpha 6
chr6_+_31462658 1.26 ENST00000538442.1
MHC class I polypeptide-related sequence B
chr4_-_47983519 1.24 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
cyclic nucleotide gated channel alpha 1
chr4_-_68749745 1.15 ENST00000283916.6
transmembrane protease, serine 11D
chr2_+_210517895 1.15 ENST00000447185.1
microtubule-associated protein 2
chr4_-_68749699 1.14 ENST00000545541.1
transmembrane protease, serine 11D
chr10_+_33271469 1.14 ENST00000414157.1
RP11-462L8.1
chr19_-_7058651 1.10 ENST00000333843.4
methyl-CpG binding domain protein 3-like 3
chr1_+_165797024 1.08 ENST00000372212.4
uridine-cytidine kinase 2
chr1_+_73771844 1.08 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
chr1_-_43855444 1.03 ENST00000372455.4
mediator complex subunit 8
chr12_+_21679220 0.98 ENST00000256969.2
chromosome 12 open reading frame 39
chr15_-_34628951 0.97 ENST00000397707.2
ENST00000560611.1
solute carrier family 12 (potassium/chloride transporter), member 6
chr19_-_7040190 0.96 ENST00000381394.4
methyl-CpG binding domain protein 3-like 4
chr4_-_140544386 0.95 ENST00000561977.1
RP11-308D13.3
chr4_-_90757364 0.93 ENST00000508895.1
synuclein, alpha (non A4 component of amyloid precursor)
chr19_+_7030589 0.93 ENST00000329753.5
methyl-CpG binding domain protein 3-like 5
chr14_+_88471468 0.92 ENST00000267549.3
G protein-coupled receptor 65
chr19_+_56989485 0.91 ENST00000585445.1
ENST00000586091.1
ENST00000594783.1
ENST00000592146.1
ENST00000588158.1
ENST00000299997.4
ENST00000591797.1
ZNF667 antisense RNA 1 (head to head)
chr11_-_125550764 0.90 ENST00000527795.1
acrosomal vesicle protein 1
chr2_+_101591314 0.85 ENST00000450763.1
neuronal PAS domain protein 2
chr2_-_65593784 0.82 ENST00000443619.2
sprouty-related, EVH1 domain containing 2
chr9_-_21142144 0.81 ENST00000380229.2
interferon, omega 1
chr12_-_8815477 0.79 ENST00000433590.2
microfibrillar associated protein 5
chr8_-_95274536 0.78 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr4_-_90756769 0.77 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)
chr3_+_26735991 0.74 ENST00000456208.2
leucine rich repeat containing 3B
chr2_-_85641162 0.74 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
capping protein (actin filament), gelsolin-like
chr11_-_5537920 0.73 ENST00000380184.1
ubiquilin-like
chr12_+_57623477 0.72 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr15_+_74165945 0.69 ENST00000535547.2
ENST00000300504.2
ENST00000562056.1
TBC1 domain family, member 21
chr4_-_156787425 0.67 ENST00000537611.2
acid-sensing (proton-gated) ion channel family member 5
chr4_-_159956333 0.66 ENST00000434826.2
chromosome 4 open reading frame 45
chr7_+_77469439 0.65 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
putative homeodomain transcription factor 2
chr21_-_27423339 0.64 ENST00000415997.1
amyloid beta (A4) precursor protein
chr19_-_49865639 0.64 ENST00000593945.1
ENST00000601519.1
ENST00000539846.1
ENST00000596757.1
ENST00000311227.2
TEA domain family member 2
chr15_+_32933866 0.64 ENST00000300175.4
ENST00000413748.2
ENST00000494364.1
ENST00000497208.1
secretogranin V (7B2 protein)
chr15_+_66797627 0.64 ENST00000565627.1
ENST00000564179.1
zwilch kinetochore protein
chr3_+_171757346 0.62 ENST00000421757.1
ENST00000415807.2
ENST00000392699.1
fibronectin type III domain containing 3B
chr11_-_125550726 0.60 ENST00000315608.3
ENST00000530048.1
acrosomal vesicle protein 1
chr12_-_8815404 0.59 ENST00000359478.2
ENST00000396549.2
microfibrillar associated protein 5
chr16_+_3068393 0.59 ENST00000573001.1
tumor necrosis factor receptor superfamily, member 12A
chr12_-_7596735 0.58 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163 molecule-like 1
chr3_-_190167571 0.58 ENST00000354905.2
transmembrane protein 207
chr7_-_102283238 0.57 ENST00000340457.8
uroplakin 3B-like
chr17_-_46115122 0.57 ENST00000006101.4
coatomer protein complex, subunit zeta 2
chr1_-_94079648 0.57 ENST00000370247.3
breast cancer anti-estrogen resistance 3
chr6_-_26124138 0.54 ENST00000314332.5
ENST00000396984.1
histone cluster 1, H2bc
chr3_+_178866199 0.53 ENST00000263967.3
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr13_+_30510003 0.52 ENST00000400540.1
long intergenic non-protein coding RNA 544
chr1_+_160765947 0.51 ENST00000263285.6
ENST00000368039.2
lymphocyte antigen 9
chr12_-_92536433 0.50 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
chromosome 12 open reading frame 79
chr12_+_1099675 0.50 ENST00000545318.2
ELKS/RAB6-interacting/CAST family member 1
chr12_-_53074182 0.50 ENST00000252244.3
keratin 1
chr1_-_16763685 0.49 ENST00000540400.1
spermatogenesis associated 21
chr2_-_239140276 0.48 ENST00000334973.4
Protein LOC151174
chr1_+_197881592 0.47 ENST00000367391.1
ENST00000367390.3
LIM homeobox 9
chr5_-_127418573 0.47 ENST00000508353.1
ENST00000508878.1
ENST00000501652.1
ENST00000514409.1
CTC-228N24.3
chr2_-_239140011 0.47 ENST00000409376.1
ENST00000409070.1
ENST00000409942.1
Protein LOC151174
chr10_+_105005644 0.46 ENST00000441178.2
ribulose-5-phosphate-3-epimerase-like 1
chr18_+_32455201 0.43 ENST00000590831.2
dystrobrevin, alpha
chr6_-_167571817 0.43 ENST00000366834.1
G protein-coupled receptor 31
chr15_+_66797455 0.43 ENST00000446801.2
zwilch kinetochore protein
chr10_+_90346519 0.42 ENST00000371939.3
lipase, family member J
chr13_-_46716969 0.41 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr6_+_11094266 0.40 ENST00000416247.2
small integral membrane protein 13
chr6_-_56507586 0.40 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
dystonin
chr4_-_164534657 0.40 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr11_+_6226782 0.40 ENST00000316375.2
chromosome 11 open reading frame 42
chr2_+_120770645 0.40 ENST00000443902.2
erythrocyte membrane protein band 4.1 like 5
chr1_-_230513367 0.39 ENST00000321327.2
ENST00000525115.1
piggyBac transposable element derived 5
chr4_+_68424434 0.39 ENST00000265404.2
ENST00000396225.1
signal transducing adaptor family member 1
chr6_-_99842041 0.39 ENST00000254759.3
ENST00000369242.1
coenzyme Q3 methyltransferase
chr12_-_102874102 0.38 ENST00000392905.2
insulin-like growth factor 1 (somatomedin C)
chr3_+_57875738 0.38 ENST00000417128.1
ENST00000438794.1
sarcolemma associated protein
chr15_-_55881135 0.38 ENST00000302000.6
pygopus family PHD finger 1
chr19_+_49866331 0.38 ENST00000597873.1
dickkopf-like 1
chr11_+_58390132 0.38 ENST00000361987.4
ciliary neurotrophic factor
chr20_+_23420322 0.38 ENST00000347397.1
cystatin-like 1
chr10_+_60936347 0.37 ENST00000373880.4
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr17_-_64225508 0.37 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr8_+_128426535 0.36 ENST00000465342.2
POU class 5 homeobox 1B
chr12_-_102874330 0.36 ENST00000307046.8
insulin-like growth factor 1 (somatomedin C)
chr15_-_66797172 0.36 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
ribosomal protein L4
chr14_+_37126765 0.35 ENST00000402703.2
paired box 9
chr1_-_179846928 0.35 ENST00000367612.3
ENST00000609928.1
torsin A interacting protein 2
chr19_+_47538560 0.35 ENST00000439365.2
ENST00000594670.1
neuronal PAS domain protein 1
chr10_+_28822636 0.35 ENST00000442148.1
ENST00000448193.1
WW domain containing adaptor with coiled-coil
chr7_-_144435985 0.35 ENST00000549981.1
thiamin pyrophosphokinase 1
chr11_+_120081475 0.33 ENST00000328965.4
OAF homolog (Drosophila)
chr3_+_63428752 0.33 ENST00000295894.5
synaptoporin
chr3_-_57233966 0.33 ENST00000473921.1
ENST00000295934.3
HESX homeobox 1
chr8_+_30244580 0.33 ENST00000523115.1
ENST00000519647.1
RNA binding protein with multiple splicing
chr8_+_38585704 0.32 ENST00000519416.1
ENST00000520615.1
transforming, acidic coiled-coil containing protein 1
chr7_+_72742178 0.31 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FK506 binding protein 6, 36kDa
chr10_+_28822417 0.31 ENST00000428935.1
ENST00000420266.1
WW domain containing adaptor with coiled-coil
chrX_-_30877837 0.30 ENST00000378930.3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr1_+_22778337 0.30 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
zinc finger and BTB domain containing 40
chr6_+_30882108 0.29 ENST00000541562.1
ENST00000421263.1
valyl-tRNA synthetase 2, mitochondrial
chr13_-_38172863 0.28 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
periostin, osteoblast specific factor
chr2_+_120770581 0.28 ENST00000263713.5
erythrocyte membrane protein band 4.1 like 5
chr10_-_36813162 0.28 ENST00000440465.1
nicotinamide phosphoribosyltransferase-like
chr6_+_26124373 0.27 ENST00000377791.2
ENST00000602637.1
histone cluster 1, H2ac
chr3_+_128444994 0.27 ENST00000482525.1
RAB7A, member RAS oncogene family
chr22_+_24407642 0.26 ENST00000454754.1
ENST00000263119.5
calcineurin binding protein 1
chr17_+_27046988 0.26 ENST00000496182.1
ribosomal protein L23a
chr8_+_85095769 0.26 ENST00000518566.1
RALY RNA binding protein-like
chr1_-_217804377 0.26 ENST00000366935.3
ENST00000366934.3
G patch domain containing 2
chr6_-_130543958 0.25 ENST00000437477.2
ENST00000439090.2
sterile alpha motif domain containing 3
chr19_+_11658655 0.25 ENST00000588935.1
calponin 1, basic, smooth muscle
chr3_+_57875711 0.25 ENST00000442599.2
sarcolemma associated protein
chr9_-_99417562 0.24 ENST00000375234.3
ENST00000446045.1
AhpC/TSA antioxidant enzyme domain containing 1
chr6_+_152130240 0.23 ENST00000427531.2
estrogen receptor 1
chr17_-_27054952 0.23 ENST00000580518.1
TLC domain containing 1
chrX_+_79591003 0.23 ENST00000538312.1
family with sequence similarity 46, member D
chrX_+_8432871 0.23 ENST00000381032.1
ENST00000453306.1
ENST00000444481.1
variable charge, X-linked 3B
chr12_-_57941004 0.22 ENST00000550750.1
ENST00000548249.1
dynactin 2 (p50)
chr17_-_79905109 0.22 ENST00000409745.2
myeloid-associated differentiation marker-like 2
chr1_-_182921119 0.22 ENST00000423786.1
SHC SH2-domain binding protein 1-like
chr10_+_50887683 0.22 ENST00000374113.3
ENST00000374111.3
ENST00000374112.3
ENST00000535836.1
chromosome 10 open reading frame 53
chr15_+_42697018 0.21 ENST00000397204.4
calpain 3, (p94)
chr2_-_74619152 0.21 ENST00000440727.1
ENST00000409240.1
dynactin 1
chr12_+_79258444 0.21 ENST00000261205.4
synaptotagmin I
chr6_+_30881982 0.21 ENST00000321897.5
ENST00000416670.2
ENST00000542001.1
ENST00000428017.1
valyl-tRNA synthetase 2, mitochondrial
chr16_+_72459838 0.20 ENST00000564508.1
AC004158.3
chr17_+_17685422 0.20 ENST00000395774.1
retinoic acid induced 1
chr20_-_34638841 0.20 ENST00000565493.1
long intergenic non-protein coding RNA 657
chr10_-_111713633 0.20 ENST00000538668.1
ENST00000369657.1
ENST00000369655.1
Uncharacterized protein
chr12_-_102874416 0.19 ENST00000392904.1
ENST00000337514.6
insulin-like growth factor 1 (somatomedin C)
chr12_-_102874378 0.19 ENST00000456098.1
insulin-like growth factor 1 (somatomedin C)
chr7_+_132937820 0.19 ENST00000393161.2
ENST00000253861.4
exocyst complex component 4
chr8_-_54755789 0.19 ENST00000359530.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr2_+_216176540 0.19 ENST00000236959.9
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr1_-_19811132 0.19 ENST00000433834.1
capping protein (actin filament) muscle Z-line, beta
chr2_+_231921574 0.18 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr7_-_115608304 0.18 ENST00000457268.1
transcription factor EC
chr2_-_55237484 0.18 ENST00000394609.2
reticulon 4
chr2_+_162016827 0.18 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TRAF family member-associated NFKB activator
chrX_+_102024075 0.18 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
long intergenic non-protein coding RNA 630
chr1_-_45452240 0.18 ENST00000372183.3
ENST00000372182.4
ENST00000360403.2
eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
chr1_+_117963209 0.17 ENST00000449370.2
mannosidase, alpha, class 1A, member 2
chr8_-_80993010 0.17 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
tumor protein D52
chr3_+_52017454 0.17 ENST00000476854.1
ENST00000476351.1
ENST00000494103.1
ENST00000404366.2
ENST00000469863.1
aminoacylase 1
chr3_+_10157276 0.17 ENST00000530758.1
ENST00000256463.6
BRICK1, SCAR/WAVE actin-nucleating complex subunit
chr15_+_42696992 0.17 ENST00000561817.1
calpain 3, (p94)
chr19_-_54619006 0.17 ENST00000391759.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr2_+_90060377 0.17 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr12_-_96429423 0.17 ENST00000228740.2
leukotriene A4 hydrolase
chr6_-_43021437 0.17 ENST00000265348.3
cullin 7
chr8_-_33424636 0.16 ENST00000256257.1
ring finger protein 122
chr17_+_27047244 0.16 ENST00000394938.4
ENST00000394935.3
ENST00000355731.4
ribosomal protein L23a
chr8_+_104383728 0.16 ENST00000330295.5
collagen triple helix repeat containing 1
chr9_+_5510492 0.16 ENST00000397745.2
programmed cell death 1 ligand 2
chr1_-_85100703 0.16 ENST00000370624.1
chromosome 1 open reading frame 180
chr2_-_24346218 0.15 ENST00000436622.1
ENST00000313213.4
profilin family, member 4
chr9_-_136006496 0.15 ENST00000372062.3
ral guanine nucleotide dissociation stimulator
chr21_-_35899113 0.15 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
regulator of calcineurin 1
chr20_+_55926583 0.15 ENST00000395840.2
ribonucleic acid export 1
chr3_+_128444965 0.15 ENST00000265062.3
RAB7A, member RAS oncogene family
chr7_+_80275621 0.15 ENST00000426978.1
ENST00000432207.1
CD36 molecule (thrombospondin receptor)
chr20_+_36373032 0.14 ENST00000373473.1
catenin, beta like 1
chr1_+_36335351 0.14 ENST00000373206.1
argonaute RISC catalytic component 1
chr11_-_57089671 0.14 ENST00000532437.1
tankyrase 1 binding protein 1, 182kDa
chr6_-_170862322 0.13 ENST00000262193.6
proteasome (prosome, macropain) subunit, beta type, 1
chr6_-_43021612 0.13 ENST00000535468.1
cullin 7
chr1_+_162602244 0.13 ENST00000367922.3
ENST00000367921.3
discoidin domain receptor tyrosine kinase 2
chr4_+_110749143 0.13 ENST00000317735.4
retinal pigment epithelium-derived rhodopsin homolog
chr2_+_90121477 0.11 ENST00000483379.1
immunoglobulin kappa variable 1D-17
chr12_-_10251603 0.11 ENST00000457018.2
C-type lectin domain family 1, member A
chrX_+_22056165 0.11 ENST00000535894.1
phosphate regulating endopeptidase homolog, X-linked
chr10_+_28822236 0.11 ENST00000347934.4
ENST00000354911.4
WW domain containing adaptor with coiled-coil
chr10_-_25010795 0.11 ENST00000416305.1
ENST00000376410.2
Rho GTPase activating protein 21
chr7_-_150329421 0.10 ENST00000493969.1
ENST00000328902.5
GTPase, IMAP family member 6
chr17_+_73629500 0.10 ENST00000375215.3
small integral membrane protein 5
chr2_-_89459813 0.10 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr1_+_91966384 0.09 ENST00000430031.2
ENST00000234626.6
cell division cycle 7
chr1_+_162039558 0.09 ENST00000530878.1
ENST00000361897.5
nitric oxide synthase 1 (neuronal) adaptor protein
chr1_+_146373546 0.09 ENST00000446760.2
neuroblastoma breakpoint family, member 12
chr1_-_240775447 0.09 ENST00000318160.4
gremlin 2, DAN family BMP antagonist
chr2_+_162016804 0.09 ENST00000392749.2
ENST00000440506.1
TRAF family member-associated NFKB activator
chr17_+_66511540 0.08 ENST00000588188.2
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr14_+_52456327 0.08 ENST00000556760.1
chromosome 14 open reading frame 166
chr1_+_197237352 0.08 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
crumbs homolog 1 (Drosophila)
chr2_+_162016916 0.08 ENST00000405852.1
TRAF family member-associated NFKB activator
chr2_+_132160448 0.07 ENST00000437751.1
long intergenic non-protein coding RNA 1120
chr2_+_120770686 0.07 ENST00000331393.4
ENST00000443124.1
erythrocyte membrane protein band 4.1 like 5
chrX_+_7810303 0.06 ENST00000381059.3
ENST00000341408.4
variable charge, X-linked
chr18_+_44812072 0.06 ENST00000598649.1
ENST00000586905.2
CTD-2130O13.1
chr3_-_64009102 0.05 ENST00000478185.1
ENST00000482510.1
ENST00000497323.1
ENST00000492933.1
ENST00000295901.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr19_-_55874611 0.05 ENST00000424985.3
family with sequence similarity 71, member E2
chr12_-_91574142 0.05 ENST00000547937.1
decorin

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXJ2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.3 1.7 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.3 1.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.3 2.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3 1.1 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 1.1 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.2 0.8 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.0 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 0.8 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2 0.7 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.2 1.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 0.5 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 1.3 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.1 0.4 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.1 0.4 GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 0.6 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 3.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 0.5 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 1.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 5.0 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.7 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.5 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.3 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.4 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.1 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.4 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.3 GO:0032571 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.1 0.4 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 1.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.8 GO:0051775 response to redox state(GO:0051775)
0.0 0.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 1.2 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.8 GO:0048339 paraxial mesoderm development(GO:0048339)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:1905033 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.9 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 2.3 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.2 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0072564 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.3 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.4 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.5 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.3 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.3 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 1.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.4 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 1.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 1.1 GO:1990423 RZZ complex(GO:1990423)
0.2 5.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 1.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 1.5 GO:0036449 microtubule minus-end(GO:0036449)
0.2 1.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 1.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 0.6 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.7 GO:0070552 BRISC complex(GO:0070552)
0.1 0.6 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 1.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 2.0 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.9 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.4 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.2 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.8 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 2.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.6 GO:0030141 secretory granule(GO:0030141)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 1.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.3 0.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 1.8 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 1.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.7 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.5 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 1.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 1.0 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.4 GO:0008169 C-methyltransferase activity(GO:0008169)
0.1 3.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 2.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.6 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 6.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 1.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 1.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742) cyclohydrolase activity(GO:0019238)
0.0 1.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.4 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.0 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 5.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.1 PID AURORA B PATHWAY Aurora B signaling
0.0 1.9 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.8 REACTOME KINESINS Genes involved in Kinesins
0.0 1.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 2.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation