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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for FOXO3_FOXD2

Z-value: 0.68

Motif logo

Transcription factors associated with FOXO3_FOXD2

Gene Symbol Gene ID Gene Info
ENSG00000118689.10 forkhead box O3
ENSG00000186564.5 forkhead box D2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXO3hg19_v2_chr6_+_108882069_108882087,
hg19_v2_chr6_+_108881012_108881038
-0.251.8e-01Click!
FOXD2hg19_v2_chr1_+_47901689_479016890.154.2e-01Click!

Activity profile of FOXO3_FOXD2 motif

Sorted Z-values of FOXO3_FOXD2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_71551652 10.44 ENST00000546561.1
tetraspanin 8
chr12_-_71551868 5.78 ENST00000247829.3
tetraspanin 8
chr14_-_65769392 4.70 ENST00000555736.1
CTD-2509G16.5
chr4_+_165675197 3.62 ENST00000515485.1
RP11-294O2.2
chr3_+_113616317 3.38 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr13_-_39564993 3.29 ENST00000423210.1
stomatin (EPB72)-like 3
chr13_+_50589390 3.25 ENST00000360473.4
ENST00000312942.1
potassium channel regulator
chr1_-_161337662 3.09 ENST00000367974.1
chromosome 1 open reading frame 192
chr10_+_51549498 2.97 ENST00000358559.2
ENST00000298239.6
microseminoprotein, beta-
chr14_+_56585048 2.95 ENST00000267460.4
pellino E3 ubiquitin protein ligase family member 2
chr4_+_165675269 2.74 ENST00000507311.1
RP11-294O2.2
chr5_-_42811986 2.39 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr1_+_227127981 2.25 ENST00000366778.1
ENST00000366777.3
ENST00000458507.2
aarF domain containing kinase 3
chr1_+_104159999 2.23 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr1_+_12806141 2.22 ENST00000288048.5
chromosome 1 open reading frame 158
chr3_+_69928256 2.12 ENST00000394355.2
microphthalmia-associated transcription factor
chr17_-_6735035 2.10 ENST00000338694.2
tektin 1
chr17_-_6735012 2.10 ENST00000535086.1
tektin 1
chr1_+_20512568 2.09 ENST00000375099.3
UBX domain protein 10
chr6_+_135502408 2.08 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
v-myb avian myeloblastosis viral oncogene homolog
chr6_+_135502466 2.05 ENST00000367814.4
v-myb avian myeloblastosis viral oncogene homolog
chr21_-_43735446 2.02 ENST00000398431.2
trefoil factor 3 (intestinal)
chr15_-_56757329 2.00 ENST00000260453.3
meiosis-specific nuclear structural 1
chr1_-_160231451 1.99 ENST00000495887.1
DDB1 and CUL4 associated factor 8
chr14_-_36983034 1.98 ENST00000518529.2
surfactant associated 3
chr3_+_181429704 1.97 ENST00000431565.2
ENST00000325404.1
SRY (sex determining region Y)-box 2
chr5_-_42812143 1.94 ENST00000514985.1
selenoprotein P, plasma, 1
chr2_+_71163051 1.93 ENST00000412314.1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr2_+_71162995 1.92 ENST00000234396.4
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr10_-_99094458 1.87 ENST00000371019.2
frequently rearranged in advanced T-cell lymphomas 2
chrX_+_119030118 1.85 ENST00000371422.1
ENST00000334356.2
A kinase (PRKA) anchor protein 14
chr2_+_97481974 1.85 ENST00000377060.3
ENST00000305510.3
cyclin M3
chr18_+_3449330 1.82 ENST00000549253.1
TGFB-induced factor homeobox 1
chr10_+_95848824 1.81 ENST00000371385.3
ENST00000371375.1
phospholipase C, epsilon 1
chrX_+_119029800 1.78 ENST00000371431.3
ENST00000371423.2
ENST00000371425.4
ENST00000394594.2
A kinase (PRKA) anchor protein 14
chr11_-_108464465 1.76 ENST00000525344.1
exophilin 5
chr7_-_95225768 1.75 ENST00000005178.5
pyruvate dehydrogenase kinase, isozyme 4
chr18_-_53070913 1.74 ENST00000568186.1
ENST00000564228.1
transcription factor 4
chr10_-_13570533 1.74 ENST00000396900.2
ENST00000396898.2
BEN domain containing 7
chr10_+_99079008 1.72 ENST00000371021.3
frequently rearranged in advanced T-cell lymphomas
chr17_+_72426891 1.72 ENST00000392627.1
G protein-coupled receptor, family C, group 5, member C
chr22_+_45809560 1.68 ENST00000342894.3
ENST00000538017.1
RIB43A domain with coiled-coils 2
chr9_-_3525968 1.67 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
regulatory factor X, 3 (influences HLA class II expression)
chr3_+_69985734 1.62 ENST00000314557.6
ENST00000394351.3
microphthalmia-associated transcription factor
chr11_+_27076764 1.61 ENST00000525090.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr5_-_13944652 1.60 ENST00000265104.4
dynein, axonemal, heavy chain 5
chr11_-_34535332 1.54 ENST00000257832.2
ENST00000429939.2
E74-like factor 5 (ets domain transcription factor)
chr18_-_53257027 1.54 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
transcription factor 4
chr13_+_43355683 1.54 ENST00000537894.1
family with sequence similarity 216, member B
chr11_-_108464321 1.52 ENST00000265843.4
exophilin 5
chr18_-_53303123 1.52 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
transcription factor 4
chr13_+_43355732 1.51 ENST00000313851.1
family with sequence similarity 216, member B
chr1_+_104293028 1.50 ENST00000370079.3
amylase, alpha 1C (salivary)
chr19_+_13906250 1.44 ENST00000254323.2
zinc finger, SWIM-type containing 4
chr5_+_140186647 1.43 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
protocadherin alpha 4
chr4_-_105416039 1.43 ENST00000394767.2
CXXC finger protein 4
chr5_+_140602904 1.42 ENST00000515856.2
ENST00000239449.4
protocadherin beta 14
chr1_-_207095324 1.42 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr20_+_9049682 1.41 ENST00000334005.3
ENST00000378473.3
phospholipase C, beta 4
chr17_-_6947225 1.41 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
solute carrier family 16, member 11
chr11_-_115375107 1.37 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
cell adhesion molecule 1
chr14_-_23288930 1.37 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_+_58755184 1.36 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
breast carcinoma amplified sequence 3
chr17_+_72427477 1.35 ENST00000342648.5
ENST00000481232.1
G protein-coupled receptor, family C, group 5, member C
chr16_+_2880157 1.35 ENST00000382280.3
zymogen granule protein 16B
chrX_-_10851762 1.35 ENST00000380785.1
ENST00000380787.1
midline 1 (Opitz/BBB syndrome)
chr7_+_114055052 1.34 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
forkhead box P2
chrX_+_37865804 1.34 ENST00000297875.2
ENST00000357972.5
synaptotagmin-like 5
chr1_-_217250231 1.34 ENST00000493748.1
ENST00000463665.1
estrogen-related receptor gamma
chr4_-_100356291 1.33 ENST00000476959.1
ENST00000482593.1
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_+_13299186 1.33 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
aryl hydrocarbon receptor nuclear translocator-like
chr7_+_116654935 1.32 ENST00000432298.1
ENST00000422922.1
suppression of tumorigenicity 7
chrX_+_9431324 1.32 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr16_+_2880369 1.31 ENST00000572863.1
zymogen granule protein 16B
chr5_+_78532003 1.30 ENST00000396137.4
junction mediating and regulatory protein, p53 cofactor
chr16_+_2880296 1.29 ENST00000571723.1
zymogen granule protein 16B
chr17_+_72733350 1.28 ENST00000392613.5
ENST00000392612.3
ENST00000392610.1
RAB37, member RAS oncogene family
chr14_-_21493649 1.27 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG family member 2
chr16_+_2880254 1.27 ENST00000570670.1
zymogen granule protein 16B
chr3_-_167098059 1.26 ENST00000392764.1
ENST00000474464.1
ENST00000392766.2
ENST00000485651.1
zinc finger, B-box domain containing
chr1_+_61542922 1.24 ENST00000407417.3
nuclear factor I/A
chr2_+_12857015 1.24 ENST00000155926.4
tribbles pseudokinase 2
chr1_+_161136180 1.22 ENST00000352210.5
ENST00000367999.4
ENST00000544598.1
ENST00000535223.1
ENST00000432542.2
protoporphyrinogen oxidase
chr2_+_12857043 1.21 ENST00000381465.2
tribbles pseudokinase 2
chr4_-_100356844 1.20 ENST00000437033.2
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr7_+_134832808 1.20 ENST00000275767.3
transmembrane protein 140
chr1_+_33722080 1.17 ENST00000483388.1
ENST00000539719.1
zinc finger protein 362
chr2_+_149402553 1.16 ENST00000258484.6
ENST00000409654.1
enhancer of polycomb homolog 2 (Drosophila)
chr16_+_69958887 1.16 ENST00000568684.1
WW domain containing E3 ubiquitin protein ligase 2
chr1_-_60392452 1.15 ENST00000371204.3
cytochrome P450, family 2, subfamily J, polypeptide 2
chr7_+_30174426 1.14 ENST00000324453.8
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr19_+_13134772 1.13 ENST00000587760.1
ENST00000585575.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr17_+_57408994 1.13 ENST00000312655.4
yippee-like 2 (Drosophila)
chr11_-_66336060 1.13 ENST00000310325.5
cathepsin F
chr4_+_76995855 1.12 ENST00000355810.4
ENST00000349321.3
ADP-ribosyltransferase 3
chr4_-_168155169 1.11 ENST00000534949.1
ENST00000535728.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr19_+_859654 1.11 ENST00000592860.1
complement factor D (adipsin)
chr3_-_114477787 1.10 ENST00000464560.1
zinc finger and BTB domain containing 20
chr1_+_87797351 1.07 ENST00000370542.1
LIM domain only 4
chr20_-_55841398 1.07 ENST00000395864.3
bone morphogenetic protein 7
chr7_+_107301065 1.06 ENST00000265715.3
solute carrier family 26 (anion exchanger), member 4
chr2_+_163175394 1.06 ENST00000446271.1
ENST00000429691.2
grancalcin, EF-hand calcium binding protein
chr12_+_12764773 1.06 ENST00000228865.2
cAMP responsive element binding protein-like 2
chr2_-_172750733 1.06 ENST00000392592.4
ENST00000422440.2
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr8_-_40755333 1.06 ENST00000297737.6
ENST00000315769.7
zinc finger, matrin-type 4
chr17_-_46035187 1.06 ENST00000300557.2
proline rich 15-like
chr17_-_30185946 1.03 ENST00000579741.1
coordinator of PRMT5, differentiation stimulator
chr6_+_32812568 1.03 ENST00000414474.1
proteasome (prosome, macropain) subunit, beta type, 9
chr10_-_28287968 1.03 ENST00000305242.5
armadillo repeat containing 4
chrX_-_38186775 1.03 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
retinitis pigmentosa GTPase regulator
chrX_-_15619076 1.03 ENST00000252519.3
angiotensin I converting enzyme 2
chr13_-_67802549 1.02 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr3_+_158288942 1.02 ENST00000491767.1
ENST00000355893.5
myeloid leukemia factor 1
chr11_+_10476851 1.02 ENST00000396553.2
adenosine monophosphate deaminase 3
chr5_+_140220769 1.02 ENST00000531613.1
ENST00000378123.3
protocadherin alpha 8
chr6_+_135502501 0.99 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
v-myb avian myeloblastosis viral oncogene homolog
chr3_+_158288960 0.99 ENST00000484955.1
ENST00000359117.5
ENST00000498592.1
ENST00000477042.1
ENST00000471745.1
ENST00000469452.1
myeloid leukemia factor 1
chr11_-_34535297 0.99 ENST00000532417.1
E74-like factor 5 (ets domain transcription factor)
chr19_-_18902106 0.99 ENST00000542601.2
ENST00000425807.1
ENST00000222271.2
cartilage oligomeric matrix protein
chr2_-_157198860 0.98 ENST00000409572.1
nuclear receptor subfamily 4, group A, member 2
chr12_+_20963647 0.95 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr3_-_121740969 0.95 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
immunoglobulin-like domain containing receptor 1
chr5_+_64920543 0.95 ENST00000399438.3
ENST00000510585.2
trafficking protein particle complex 13
CDNA FLJ26957 fis, clone SLV00486; Uncharacterized protein
chr12_+_20963632 0.94 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr20_+_52105495 0.92 ENST00000439873.2
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr6_-_87804815 0.92 ENST00000369582.2
glycoprotein hormones, alpha polypeptide
chr20_-_3762087 0.92 ENST00000379756.3
sperm flagellar 1
chr12_-_91574142 0.92 ENST00000547937.1
decorin
chr21_-_43735628 0.90 ENST00000291525.10
ENST00000518498.1
trefoil factor 3 (intestinal)
chr6_+_151815143 0.90 ENST00000239374.7
ENST00000367290.5
coiled-coil domain containing 170
chr3_-_141868357 0.90 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
transcription factor Dp-2 (E2F dimerization partner 2)
chr19_+_859425 0.89 ENST00000327726.6
complement factor D (adipsin)
chr1_+_246729724 0.89 ENST00000366513.4
ENST00000366512.3
consortin, connexin sorting protein
chr4_-_70518941 0.89 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr4_-_100356551 0.88 ENST00000209665.4
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr18_+_61575200 0.88 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr14_-_65569057 0.87 ENST00000555419.1
ENST00000341653.2
MYC associated factor X
chr20_+_48429233 0.87 ENST00000417961.1
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chrX_-_136113833 0.86 ENST00000298110.1
G protein-coupled receptor 101
chr14_-_76447494 0.86 ENST00000238682.3
transforming growth factor, beta 3
chr15_+_78558523 0.85 ENST00000446172.2
DnaJ (Hsp40) homolog, subfamily A, member 4
chr13_+_52598827 0.85 ENST00000521776.2
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr18_-_53177984 0.84 ENST00000543082.1
transcription factor 4
chr17_-_30185971 0.84 ENST00000378634.2
coordinator of PRMT5, differentiation stimulator
chr6_-_32634425 0.83 ENST00000399082.3
ENST00000399079.3
ENST00000374943.4
ENST00000434651.2
major histocompatibility complex, class II, DQ beta 1
chr3_+_158288999 0.82 ENST00000482628.1
ENST00000478894.2
ENST00000392822.3
ENST00000466246.1
myeloid leukemia factor 1
chr5_-_146833485 0.82 ENST00000398514.3
dihydropyrimidinase-like 3
chr4_-_123542224 0.81 ENST00000264497.3
interleukin 21
chr5_-_110062349 0.80 ENST00000511883.2
ENST00000455884.2
transmembrane protein 232
chr2_-_27435125 0.79 ENST00000414408.1
ENST00000310574.3
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr1_-_207095212 0.79 ENST00000420007.2
Fas apoptotic inhibitory molecule 3
chr5_+_36608422 0.79 ENST00000381918.3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_114477962 0.78 ENST00000471418.1
zinc finger and BTB domain containing 20
chr8_+_99956662 0.78 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
odd-skipped related transciption factor 2
chr21_-_47738112 0.78 ENST00000417060.1
chromosome 21 open reading frame 58
chr20_+_48429356 0.78 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr17_-_40897043 0.78 ENST00000428826.2
ENST00000592492.1
ENST00000585893.1
ENST00000593214.1
ENST00000590078.1
ENST00000586382.1
ENST00000415827.2
ENST00000592743.1
ENST00000586089.1
ENST00000435174.1
enhancer of zeste homolog 1 (Drosophila)
chr9_-_98269481 0.77 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
patched 1
chr9_-_37465396 0.77 ENST00000307750.4
zinc finger and BTB domain containing 5
chr3_+_171561127 0.77 ENST00000334567.5
ENST00000450693.1
transmembrane protein 212
chr17_-_39165366 0.77 ENST00000391588.1
keratin associated protein 3-1
chr22_-_31741757 0.76 ENST00000215919.3
POZ (BTB) and AT hook containing zinc finger 1
chr4_+_86396265 0.74 ENST00000395184.1
Rho GTPase activating protein 24
chr8_-_133637624 0.74 ENST00000522789.1
leucine rich repeat containing 6
chr2_-_160472952 0.73 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
bromodomain adjacent to zinc finger domain, 2B
chr7_-_6098770 0.72 ENST00000536084.1
ENST00000446699.1
ENST00000199389.6
eukaryotic translation initiation factor 2-alpha kinase 1
chr2_-_152146385 0.72 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chr4_+_74606223 0.72 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr14_-_21493884 0.72 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG family member 2
chr11_-_26593779 0.72 ENST00000529533.1
mucin 15, cell surface associated
chr8_-_133772794 0.71 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
transmembrane protein 71
chr3_-_168865522 0.71 ENST00000464456.1
MDS1 and EVI1 complex locus
chr17_+_68071389 0.71 ENST00000283936.1
ENST00000392671.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr19_-_47734448 0.71 ENST00000439096.2
BCL2 binding component 3
chr17_+_68071458 0.71 ENST00000589377.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr9_-_88897426 0.70 ENST00000375991.4
ENST00000326094.4
iron-sulfur cluster assembly 1
chr14_-_31926701 0.70 ENST00000310850.4
D-tyrosyl-tRNA deacylase 2 (putative)
chr8_+_95907993 0.70 ENST00000523378.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr5_-_16509101 0.70 ENST00000399793.2
family with sequence similarity 134, member B
chr9_+_27109392 0.69 ENST00000406359.4
TEK tyrosine kinase, endothelial
chr10_+_123923205 0.69 ENST00000369004.3
ENST00000260733.3
transforming, acidic coiled-coil containing protein 2
chr17_+_4618734 0.68 ENST00000571206.1
arrestin, beta 2
chr5_-_40755987 0.68 ENST00000337702.4
tetratricopeptide repeat domain 33
chr7_+_35756186 0.67 ENST00000430518.1
AC018647.3
chr17_-_77925806 0.67 ENST00000574241.2
TBC1 domain family, member 16
chr14_-_102605983 0.66 ENST00000334701.7
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr5_+_140165876 0.66 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
protocadherin alpha 1
chr11_-_85397167 0.65 ENST00000316398.3
coiled-coil domain containing 89
chr1_-_86848760 0.65 ENST00000460698.2
outer dense fiber of sperm tails 2-like
chr10_+_123922941 0.65 ENST00000360561.3
transforming, acidic coiled-coil containing protein 2
chr12_+_41831485 0.65 ENST00000539469.2
ENST00000298919.7
PDZ domain containing ring finger 4
chr2_-_71454185 0.65 ENST00000244221.8
poly(A) binding protein interacting protein 2B
chr20_-_55841662 0.65 ENST00000395863.3
ENST00000450594.2
bone morphogenetic protein 7
chr14_-_91526922 0.63 ENST00000418736.2
ENST00000261991.3
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr8_+_95908041 0.63 ENST00000396113.1
ENST00000519136.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr6_-_79944336 0.63 ENST00000344726.5
ENST00000275036.7
high mobility group nucleosomal binding domain 3
chr16_-_84150492 0.62 ENST00000343411.3
membrane-bound transcription factor peptidase, site 1
chr15_-_31283798 0.62 ENST00000435680.1
ENST00000425768.1
myotubularin related protein 10
chr7_+_91570165 0.62 ENST00000356239.3
ENST00000359028.2
ENST00000358100.2
A kinase (PRKA) anchor protein 9
chr7_-_16844611 0.61 ENST00000401412.1
ENST00000419304.2
anterior gradient 2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO3_FOXD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
1.1 3.4 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.6 1.7 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.5 2.0 GO:1905069 allantois development(GO:1905069)
0.5 2.4 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.5 1.9 GO:0010157 response to chlorate(GO:0010157)
0.4 1.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.4 2.5 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.4 2.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 1.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 0.3 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.3 1.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.3 1.0 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 2.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.3 0.9 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.3 0.9 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.3 0.8 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 1.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 4.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.2 1.4 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 2.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.2 1.4 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.2 0.9 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 3.6 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.2 1.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 1.0 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.2 1.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 1.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2 0.7 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.2 0.9 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 1.9 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.2 1.0 GO:0006196 AMP catabolic process(GO:0006196)
0.2 0.5 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.2 0.7 GO:0043335 protein unfolding(GO:0043335)
0.2 1.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 13.4 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.2 3.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 2.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 2.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 1.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.7 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 3.3 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.6 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.7 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.6 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.4 GO:0034241 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.1 1.0 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.5 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.9 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 3.4 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.1 0.4 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 1.1 GO:0015705 iodide transport(GO:0015705)
0.1 0.6 GO:1902617 response to fluoride(GO:1902617)
0.1 2.3 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.3 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.5 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.9 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 0.4 GO:0021592 fourth ventricle development(GO:0021592)
0.1 1.1 GO:0042659 regulation of cell fate specification(GO:0042659)
0.1 0.4 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.6 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 1.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.2 GO:0051451 myoblast migration(GO:0051451)
0.1 1.0 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.4 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.1 0.8 GO:0051182 coenzyme transport(GO:0051182)
0.1 1.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.3 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 3.5 GO:0090383 phagosome acidification(GO:0090383)
0.1 2.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.9 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1 1.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.3 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.1 1.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.1 GO:0032276 regulation of gonadotropin secretion(GO:0032276) negative regulation of gonadotropin secretion(GO:0032277)
0.1 0.4 GO:0051029 rRNA transport(GO:0051029)
0.1 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.3 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 4.0 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 0.2 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 1.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.3 GO:1990535 transformation of host cell by virus(GO:0019087) neuron projection maintenance(GO:1990535)
0.1 0.4 GO:1901668 corpus callosum morphogenesis(GO:0021540) regulation of superoxide dismutase activity(GO:1901668)
0.1 0.4 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.8 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.5 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 1.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.4 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.6 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 5.0 GO:0001895 retina homeostasis(GO:0001895)
0.1 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.2 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.1 0.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 1.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 1.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.7 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 1.2 GO:0072189 ureter development(GO:0072189)
0.1 1.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.2 GO:1903770 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 2.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0002840 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.5 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.4 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.3 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188) histone H3-K27 demethylation(GO:0071557)
0.0 0.4 GO:0060767 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.5 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.6 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.9 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.9 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.8 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.4 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0030421 defecation(GO:0030421)
0.0 2.8 GO:0048678 response to axon injury(GO:0048678)
0.0 1.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.6 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.3 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.8 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.4 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.5 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.1 GO:0001505 regulation of neurotransmitter levels(GO:0001505)
0.0 1.1 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 4.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057) operant conditioning(GO:0035106)
0.0 2.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.4 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 1.2 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 1.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.0 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.9 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.1 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.7 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0071043 nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.4 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.3 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 1.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.4 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.6 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 1.1 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.4 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0019682 fructose catabolic process(GO:0006001) glyceraldehyde-3-phosphate metabolic process(GO:0019682) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 3.5 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 1.2 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 1.5 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0071888 macrophage apoptotic process(GO:0071888)
0.0 1.1 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.2 GO:0002192 IRES-dependent translational initiation(GO:0002192) IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0009304 tRNA transcription(GO:0009304) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.3 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 1.0 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.2 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1902636 kinociliary basal body(GO:1902636)
0.3 3.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 1.9 GO:0044294 dendritic growth cone(GO:0044294)
0.2 1.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 0.5 GO:0034657 GID complex(GO:0034657)
0.2 1.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.5 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.3 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.3 GO:0044609 DBIRD complex(GO:0044609)
0.1 1.0 GO:0061689 tricellular tight junction(GO:0061689)
0.1 2.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:0036398 TCR signalosome(GO:0036398)
0.1 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 2.0 GO:0042599 lamellar body(GO:0042599)
0.1 0.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.7 GO:0033269 internode region of axon(GO:0033269)
0.1 1.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 3.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.3 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.5 GO:0030175 filopodium(GO:0030175)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.0 GO:0033391 chromatoid body(GO:0033391)
0.1 6.4 GO:0036126 sperm flagellum(GO:0036126)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 1.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.9 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.8 GO:0043194 axon initial segment(GO:0043194)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.9 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.1 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 5.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.3 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.0 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 5.0 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 2.0 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.3 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 2.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.5 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0001726 ruffle(GO:0001726)
0.0 0.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.6 2.2 GO:0016160 amylase activity(GO:0016160)
0.5 6.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 1.4 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.4 1.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4 5.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4 1.3 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.4 1.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 1.9 GO:0005119 smoothened binding(GO:0005119)
0.3 1.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.3 0.8 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 0.7 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.2 0.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 1.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 1.0 GO:0002046 opsin binding(GO:0002046)
0.2 1.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 0.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 2.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.9 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.4 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.6 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 1.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 1.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.5 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.4 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.9 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.5 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 5.9 GO:0070888 E-box binding(GO:0070888)
0.1 1.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.5 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 1.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 3.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.6 GO:0035500 MH2 domain binding(GO:0035500)
0.1 0.9 GO:0071253 connexin binding(GO:0071253)
0.1 2.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 2.6 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 1.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.7 GO:0030911 TPR domain binding(GO:0030911)
0.1 1.8 GO:0035198 miRNA binding(GO:0035198)
0.1 0.3 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.6 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 1.4 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.9 GO:0004935 adrenergic receptor activity(GO:0004935)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.8 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 1.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.6 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 0.4 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 1.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.2 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.5 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.2 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 1.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.4 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.0 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0043559 insulin binding(GO:0043559) PTB domain binding(GO:0051425)
0.0 1.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 5.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 1.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.9 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 3.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 2.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 3.4 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0015197 peptide transporter activity(GO:0015197)
0.0 1.6 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 1.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 1.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.0 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.9 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.7 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.1 0.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 4.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 9.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 5.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.7 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.8 PID SHP2 PATHWAY SHP2 signaling
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID FOXO PATHWAY FoxO family signaling
0.0 1.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID MTOR 4PATHWAY mTOR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 3.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 3.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 6.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 3.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 3.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.8 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 1.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 2.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.6 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.9 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 2.1 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 1.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac