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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for FOXO4

Z-value: 0.80

Motif logo

Transcription factors associated with FOXO4

Gene Symbol Gene ID Gene Info
ENSG00000184481.12 forkhead box O4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXO4hg19_v2_chrX_+_70316005_70316047-0.523.3e-03Click!

Activity profile of FOXO4 motif

Sorted Z-values of FOXO4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_27109392 3.76 ENST00000406359.4
TEK tyrosine kinase, endothelial
chr13_-_39564993 2.10 ENST00000423210.1
stomatin (EPB72)-like 3
chr20_-_21494654 2.00 ENST00000377142.4
NK2 homeobox 2
chr2_+_42104692 1.46 ENST00000398796.2
ENST00000442214.1
AC104654.1
chr12_-_111358372 1.31 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chr5_-_110062384 1.27 ENST00000429839.2
transmembrane protein 232
chr6_-_152489484 1.25 ENST00000354674.4
ENST00000539504.1
spectrin repeat containing, nuclear envelope 1
chr5_-_110062349 1.25 ENST00000511883.2
ENST00000455884.2
transmembrane protein 232
chr12_-_68696652 1.21 ENST00000539972.1
Mdm1 nuclear protein homolog (mouse)
chr2_+_58655461 1.15 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
long intergenic non-protein coding RNA 1122
chr22_+_45809560 1.02 ENST00000342894.3
ENST00000538017.1
RIB43A domain with coiled-coils 2
chr11_-_114466471 1.00 ENST00000424261.2
neurexophilin and PC-esterase domain family, member 4
chr13_+_24144509 0.98 ENST00000248484.4
tumor necrosis factor receptor superfamily, member 19
chr1_+_63989004 0.94 ENST00000371088.4
EF-hand calcium binding domain 7
chr9_+_27109133 0.94 ENST00000519097.1
ENST00000380036.4
TEK tyrosine kinase, endothelial
chr5_-_137674000 0.93 ENST00000510119.1
ENST00000513970.1
cell division cycle 25C
chr17_+_17876127 0.92 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
leucine rich repeat containing 48
chr7_-_25702669 0.91 ENST00000446840.1
AC003090.1
chr6_-_31651817 0.90 ENST00000375863.3
ENST00000375860.2
lymphocyte antigen 6 complex, locus G5C
chr8_-_133772794 0.89 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
transmembrane protein 71
chr8_-_72459885 0.83 ENST00000523987.1
Uncharacterized protein
chr19_+_859654 0.81 ENST00000592860.1
complement factor D (adipsin)
chr17_-_30185946 0.80 ENST00000579741.1
coordinator of PRMT5, differentiation stimulator
chr6_+_72596604 0.79 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
regulating synaptic membrane exocytosis 1
chr13_+_24144796 0.79 ENST00000403372.2
tumor necrosis factor receptor superfamily, member 19
chr3_-_57530051 0.77 ENST00000311202.6
ENST00000351747.2
ENST00000495027.1
ENST00000389536.4
dynein, axonemal, heavy chain 12
chr3_+_159570722 0.77 ENST00000482804.1
schwannomin interacting protein 1
chr7_+_7811992 0.77 ENST00000406829.1
RPA3 antisense RNA 1
chr11_-_62477041 0.70 ENST00000433053.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr16_-_86542455 0.68 ENST00000595886.1
ENST00000597578.1
ENST00000593604.1
FOXF1 adjacent non-coding developmental regulatory RNA
chr14_-_64108125 0.68 ENST00000267522.3
WD repeat domain 89
chr3_+_132316081 0.67 ENST00000249887.2
atypical chemokine receptor 4
chr14_+_102276192 0.66 ENST00000557714.1
protein phosphatase 2, regulatory subunit B', gamma
chr17_-_46806540 0.66 ENST00000290295.7
homeobox B13
chr2_+_233527443 0.65 ENST00000410095.1
EF-hand domain family, member D1
chr10_-_82049424 0.64 ENST00000372213.3
methionine adenosyltransferase I, alpha
chr12_-_10251576 0.63 ENST00000315330.4
C-type lectin domain family 1, member A
chr4_-_70518941 0.62 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr8_+_31497271 0.61 ENST00000520407.1
neuregulin 1
chr11_-_62476965 0.61 ENST00000405837.1
ENST00000531524.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr6_-_87804815 0.61 ENST00000369582.2
glycoprotein hormones, alpha polypeptide
chr12_-_10251603 0.59 ENST00000457018.2
C-type lectin domain family 1, member A
chr3_+_148447887 0.59 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
angiotensin II receptor, type 1
chr5_+_64920543 0.57 ENST00000399438.3
ENST00000510585.2
trafficking protein particle complex 13
CDNA FLJ26957 fis, clone SLV00486; Uncharacterized protein
chr11_-_85397167 0.56 ENST00000316398.3
coiled-coil domain containing 89
chr9_-_39288092 0.56 ENST00000323947.7
ENST00000297668.6
ENST00000377656.2
ENST00000377659.1
contactin associated protein-like 3
chr14_-_61124977 0.55 ENST00000554986.1
SIX homeobox 1
chr17_-_30185971 0.53 ENST00000378634.2
coordinator of PRMT5, differentiation stimulator
chr1_+_174844645 0.51 ENST00000486220.1
RAB GTPase activating protein 1-like
chr7_-_6098770 0.51 ENST00000536084.1
ENST00000446699.1
ENST00000199389.6
eukaryotic translation initiation factor 2-alpha kinase 1
chr9_-_13175823 0.50 ENST00000545857.1
multiple PDZ domain protein
chr3_+_98072698 0.49 ENST00000354924.2
olfactory receptor, family 5, subfamily K, member 4
chr1_-_157811588 0.49 ENST00000368174.4
CD5 molecule-like
chr1_+_153940346 0.49 ENST00000405694.3
ENST00000449724.1
ENST00000368607.3
ENST00000271889.4
cAMP responsive element binding protein 3-like 4
chr1_+_153940713 0.48 ENST00000368601.1
ENST00000368603.1
ENST00000368600.3
cAMP responsive element binding protein 3-like 4
chr10_-_61900762 0.48 ENST00000355288.2
ankyrin 3, node of Ranvier (ankyrin G)
chr9_-_86432547 0.48 ENST00000376365.3
ENST00000376371.2
G kinase anchoring protein 1
chr5_-_10308125 0.47 ENST00000296658.3
carboxymethylenebutenolidase homolog (Pseudomonas)
chr1_-_54405773 0.46 ENST00000371376.1
heat shock protein family B (small), member 11
chr3_-_3151664 0.46 ENST00000256452.3
ENST00000311981.8
ENST00000430514.2
ENST00000456302.1
interleukin 5 receptor, alpha
chr9_-_15472730 0.46 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chr19_-_58662139 0.46 ENST00000598312.1
zinc finger protein 329
chr7_+_134832808 0.46 ENST00000275767.3
transmembrane protein 140
chr19_+_13906250 0.45 ENST00000254323.2
zinc finger, SWIM-type containing 4
chr7_+_120628731 0.45 ENST00000310396.5
cadherin-like and PC-esterase domain containing 1
chr10_-_13570533 0.44 ENST00000396900.2
ENST00000396898.2
BEN domain containing 7
chr11_+_127140956 0.44 ENST00000608214.1
RP11-480C22.1
chrX_-_114252193 0.43 ENST00000243213.1
interleukin 13 receptor, alpha 2
chr11_-_77531752 0.42 ENST00000440064.2
ENST00000528095.1
remodeling and spacing factor 1
chr10_-_90751038 0.42 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
actin, alpha 2, smooth muscle, aorta
chr1_+_160765919 0.41 ENST00000341032.4
ENST00000368041.2
ENST00000368040.1
lymphocyte antigen 9
chr17_+_67410832 0.40 ENST00000590474.1
mitogen-activated protein kinase kinase 6
chr10_-_62332357 0.40 ENST00000503366.1
ankyrin 3, node of Ranvier (ankyrin G)
chr4_-_155511887 0.39 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr3_+_160394940 0.39 ENST00000320767.2
ADP-ribosylation factor-like 14
chr14_-_103987679 0.39 ENST00000553610.1
creatine kinase, brain
chr1_+_160765884 0.38 ENST00000392203.4
lymphocyte antigen 9
chr5_-_133706695 0.38 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
cyclin-dependent kinase-like 3
chr1_+_160765860 0.38 ENST00000368037.5
lymphocyte antigen 9
chr18_+_32073253 0.37 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
dystrobrevin, alpha
chr5_+_79703823 0.37 ENST00000338008.5
ENST00000510158.1
ENST00000505560.1
zinc finger, FYVE domain containing 16
chr2_-_148779106 0.36 ENST00000416719.1
ENST00000264169.2
origin recognition complex, subunit 4
chr6_-_29013017 0.36 ENST00000377175.1
olfactory receptor, family 2, subfamily W, member 1
chrX_+_9431324 0.35 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr2_+_177025619 0.35 ENST00000410016.1
homeobox D3
chr7_-_105332084 0.35 ENST00000472195.1
ataxin 7-like 1
chr15_+_49462434 0.35 ENST00000558145.1
ENST00000543495.1
ENST00000544523.1
ENST00000560138.1
galactokinase 2
chr2_-_101767715 0.35 ENST00000376840.4
ENST00000409318.1
TBC1 domain family, member 8 (with GRAM domain)
chr12_-_57472522 0.35 ENST00000379391.3
ENST00000300128.4
transmembrane protein 194A
chr5_+_137203465 0.34 ENST00000239926.4
myotilin
chr3_-_52868931 0.34 ENST00000486659.1
musculoskeletal, embryonic nuclear protein 1
chr1_+_236686717 0.34 ENST00000341872.6
ENST00000450372.2
lectin, galactoside-binding, soluble, 8
chr1_-_57431679 0.34 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
complement component 8, beta polypeptide
chr12_+_54378923 0.33 ENST00000303460.4
homeobox C10
chr5_-_125930929 0.33 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
aldehyde dehydrogenase 7 family, member A1
chr20_+_44035200 0.33 ENST00000372717.1
ENST00000360981.4
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr18_+_77160282 0.33 ENST00000318065.5
ENST00000545796.1
ENST00000592223.1
ENST00000329101.4
ENST00000586434.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr3_-_71632894 0.33 ENST00000493089.1
forkhead box P1
chr3_-_71179988 0.32 ENST00000491238.1
forkhead box P1
chr12_-_100486668 0.32 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
UHRF1 binding protein 1-like
chr20_+_44035847 0.32 ENST00000372712.2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr16_+_84801852 0.32 ENST00000569925.1
ENST00000567526.1
ubiquitin specific peptidase 10
chr3_-_71294304 0.32 ENST00000498215.1
forkhead box P1
chr3_-_52869205 0.31 ENST00000446157.2
musculoskeletal, embryonic nuclear protein 1
chr17_+_33474826 0.31 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
unc-45 homolog B (C. elegans)
chr14_+_102276132 0.31 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
protein phosphatase 2, regulatory subunit B', gamma
chr17_+_33474860 0.31 ENST00000394570.2
unc-45 homolog B (C. elegans)
chr3_-_150920979 0.31 ENST00000309180.5
ENST00000480322.1
G protein-coupled receptor 171
chr1_-_207095324 0.31 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr9_-_95186739 0.30 ENST00000375550.4
osteomodulin
chr7_-_37026108 0.30 ENST00000396045.3
engulfment and cell motility 1
chr18_+_72922710 0.30 ENST00000322038.5
teashirt zinc finger homeobox 1
chr2_+_191513959 0.30 ENST00000337386.5
ENST00000357215.5
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr11_-_5173599 0.29 ENST00000328942.1
olfactory receptor, family 52, subfamily A, member 1
chr14_+_94577074 0.29 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
interferon, alpha-inducible protein 27
chr3_+_101504200 0.29 ENST00000422132.1
neurexophilin and PC-esterase domain family, member 3
chr1_+_10490127 0.29 ENST00000602787.1
ENST00000602296.1
ENST00000400900.2
apoptosis-inducing, TAF9-like domain 1
APITD1-CORT readthrough
chr6_+_126277842 0.29 ENST00000229633.5
histidine triad nucleotide binding protein 3
chr4_+_184365744 0.28 ENST00000504169.1
ENST00000302350.4
CDKN2A interacting protein
chr12_-_71031185 0.28 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
protein tyrosine phosphatase, receptor type, B
chr10_-_118032979 0.28 ENST00000355422.6
GDNF family receptor alpha 1
chr13_+_32838801 0.27 ENST00000542859.1
furry homolog (Drosophila)
chr7_+_151038850 0.27 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
negative regulator of ubiquitin-like proteins 1
chr17_-_67138015 0.27 ENST00000284425.2
ENST00000590645.1
ATP-binding cassette, sub-family A (ABC1), member 6
chr9_-_136933615 0.27 ENST00000371834.2
bromodomain containing 3
chr1_-_207095212 0.26 ENST00000420007.2
Fas apoptotic inhibitory molecule 3
chr2_+_109204743 0.26 ENST00000332345.6
LIM and senescent cell antigen-like domains 1
chr3_-_28390120 0.26 ENST00000334100.6
5-azacytidine induced 2
chr3_-_28390415 0.26 ENST00000414162.1
ENST00000420543.2
5-azacytidine induced 2
chr2_-_71454185 0.26 ENST00000244221.8
poly(A) binding protein interacting protein 2B
chr2_+_109204909 0.26 ENST00000393310.1
LIM and senescent cell antigen-like domains 1
chr9_+_108006880 0.26 ENST00000374723.1
ENST00000374720.3
ENST00000374724.1
solute carrier family 44 (choline transporter), member 1
chr16_-_18887627 0.26 ENST00000563235.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr8_-_42698433 0.25 ENST00000345117.2
ENST00000254250.3
THAP domain containing, apoptosis associated protein 1
chr11_-_77531858 0.25 ENST00000360355.2
remodeling and spacing factor 1
chr11_-_89224299 0.25 ENST00000343727.5
ENST00000531342.1
ENST00000375979.3
NADPH oxidase 4
chr1_+_154193325 0.25 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
ubiquitin associated protein 2-like
chr17_-_49021974 0.25 ENST00000501718.2
RP11-700H6.1
chr11_+_112130988 0.25 ENST00000595053.1
LOC100132686 protein; Uncharacterized protein
chr11_-_123612319 0.24 ENST00000526252.1
ENST00000530393.1
ENST00000533463.1
ENST00000336139.4
ENST00000529691.1
ENST00000528306.1
zinc finger protein 202
chr1_-_150669500 0.24 ENST00000271732.3
golgi phosphoprotein 3-like
chr11_-_107328527 0.24 ENST00000282251.5
ENST00000433523.1
CWF19-like 2, cell cycle control (S. pombe)
chr4_-_186696425 0.24 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chrX_+_100743031 0.24 ENST00000423738.3
armadillo repeat containing, X-linked 4
chr3_-_101232019 0.24 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SUMO1/sentrin specific peptidase 7
chr15_+_59397275 0.24 ENST00000288207.2
cyclin B2
chrX_-_101726732 0.24 ENST00000457521.2
ENST00000412230.2
ENST00000453326.2
nuclear RNA export factor 2B
t-complex 11 family, X-linked 2
chr4_+_78804393 0.24 ENST00000502384.1
mitochondrial ribosomal protein L1
chrX_+_101470280 0.24 ENST00000395088.2
ENST00000330252.5
ENST00000333110.5
nuclear RNA export factor 2
t-complex 11 family, X-linked 1
chr11_-_94227029 0.24 ENST00000323977.3
ENST00000536754.1
ENST00000323929.3
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
chr16_+_69958887 0.23 ENST00000568684.1
WW domain containing E3 ubiquitin protein ligase 2
chr4_-_186697044 0.23 ENST00000437304.2
sorbin and SH3 domain containing 2
chr1_+_97188188 0.23 ENST00000541987.1
polypyrimidine tract binding protein 2
chr7_+_129906660 0.23 ENST00000222481.4
carboxypeptidase A2 (pancreatic)
chr8_-_87755878 0.22 ENST00000320005.5
cyclic nucleotide gated channel beta 3
chr3_+_124223586 0.22 ENST00000393496.1
kalirin, RhoGEF kinase
chr1_+_28879588 0.22 ENST00000373830.3
tRNA selenocysteine 1 associated protein 1
chr3_-_28390581 0.22 ENST00000479665.1
5-azacytidine induced 2
chr2_+_182850551 0.22 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr13_+_103459704 0.22 ENST00000602836.1
BIVM-ERCC5 readthrough
chr13_-_38443860 0.21 ENST00000426868.2
ENST00000379681.3
ENST00000338947.5
ENST00000355779.2
ENST00000358477.2
ENST00000379673.2
transient receptor potential cation channel, subfamily C, member 4
chr10_-_1246300 0.21 ENST00000381310.3
adenosine deaminase, RNA-specific, B2 (non-functional)
chr16_+_28943260 0.20 ENST00000538922.1
ENST00000324662.3
ENST00000567541.1
CD19 molecule
chr6_-_32122106 0.19 ENST00000428778.1
proline-rich transmembrane protein 1
chr7_-_141673573 0.19 ENST00000547270.1
taste receptor, type 2, member 38
chr10_-_25241499 0.19 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
phosphoribosyl transferase domain containing 1
chr14_+_102606181 0.19 ENST00000335263.5
ENST00000322340.5
ENST00000424963.2
ENST00000342702.3
ENST00000556807.1
ENST00000499851.2
ENST00000558567.1
ENST00000299135.6
ENST00000454394.2
ENST00000556511.2
WD repeat domain 20
chr19_-_40791302 0.19 ENST00000392038.2
ENST00000578123.1
v-akt murine thymoma viral oncogene homolog 2
chr6_+_97010424 0.19 ENST00000541107.1
ENST00000450218.1
ENST00000326771.2
four and a half LIM domains 5
chr6_-_167571817 0.18 ENST00000366834.1
G protein-coupled receptor 31
chr14_-_102605983 0.18 ENST00000334701.7
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr5_+_98104978 0.18 ENST00000308234.7
repulsive guidance molecule family member b
chrX_-_70329118 0.18 ENST00000374188.3
interleukin 2 receptor, gamma
chr8_+_50824233 0.17 ENST00000522124.1
syntrophin, gamma 1
chr18_+_28898052 0.17 ENST00000257192.4
desmoglein 1
chr20_+_17680587 0.17 ENST00000427254.1
ENST00000377805.3
barrier to autointegration factor 2
chr1_+_150122034 0.17 ENST00000025469.6
ENST00000369124.4
pleckstrin homology domain containing, family O member 1
chr13_-_36944307 0.17 ENST00000355182.4
spastic paraplegia 20 (Troyer syndrome)
chr2_+_65283506 0.17 ENST00000377990.2
centrosomal protein 68kDa
chr12_+_118454500 0.17 ENST00000537315.1
ENST00000229043.3
ENST00000484086.2
ENST00000420967.1
ENST00000454402.2
ENST00000392542.2
ENST00000535092.1
replication factor C (activator 1) 5, 36.5kDa
chr5_+_135468516 0.16 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD family member 5
chr19_+_15160130 0.16 ENST00000427043.3
caspase 14, apoptosis-related cysteine peptidase
chrX_-_148676974 0.16 ENST00000524178.1
heat shock transcription factor family, X linked 2
chr8_+_74903580 0.16 ENST00000284818.2
ENST00000518893.1
lymphocyte antigen 96
chrX_+_148855726 0.15 ENST00000370416.4
heat shock transcription factor family, X linked 1
chr11_-_55703876 0.15 ENST00000301532.3
olfactory receptor, family 5, subfamily I, member 1
chr4_+_74347400 0.15 ENST00000226355.3
afamin
chr12_-_10251539 0.15 ENST00000420265.2
C-type lectin domain family 1, member A
chr17_-_40897043 0.15 ENST00000428826.2
ENST00000592492.1
ENST00000585893.1
ENST00000593214.1
ENST00000590078.1
ENST00000586382.1
ENST00000415827.2
ENST00000592743.1
ENST00000586089.1
ENST00000435174.1
enhancer of zeste homolog 1 (Drosophila)
chr1_+_151739131 0.15 ENST00000400999.1
ornithine decarboxylase antizyme 3
chr13_-_36920420 0.15 ENST00000438666.2
spastic paraplegia 20 (Troyer syndrome)
chr18_+_47088401 0.15 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
lipase, endothelial
chr12_+_6881678 0.14 ENST00000441671.2
ENST00000203629.2
lymphocyte-activation gene 3
chr2_-_166060552 0.14 ENST00000283254.7
ENST00000453007.1
sodium channel, voltage-gated, type III, alpha subunit
chr1_+_47533160 0.14 ENST00000334194.3
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr1_-_153514241 0.14 ENST00000368718.1
ENST00000359215.1
S100 calcium binding protein A5
chr18_-_30716038 0.14 ENST00000581852.1
coiled-coil domain containing 178
chr3_+_169490606 0.14 ENST00000349841.5
myoneurin
chr10_-_118032697 0.14 ENST00000439649.3
GDNF family receptor alpha 1
chr1_+_92545862 0.14 ENST00000370382.3
ENST00000342818.3
BTB (POZ) domain containing 8

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.6 4.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 0.9 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 1.0 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 0.8 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 0.7 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 0.5 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.6 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.6 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 1.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.5 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 1.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 1.3 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 1.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.6 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.3 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.4 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.3 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.1 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.2 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 1.2 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.1 0.4 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.2 GO:0071484 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.0 1.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.4 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.3 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.1 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.0 0.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.8 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.3 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.5 GO:0071466 xenobiotic metabolic process(GO:0006805) response to xenobiotic stimulus(GO:0009410) cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.7 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.5 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.9 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0002870 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.0 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.5 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.2 GO:0051451 myoblast migration(GO:0051451)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.0 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0007039 protein catabolic process in the vacuole(GO:0007039)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0031213 RSF complex(GO:0031213)
0.1 5.7 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.3 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.3 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.8 GO:0030286 dynein complex(GO:0030286)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.2 0.5 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.4 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.2 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.5 GO:0005521 lamin binding(GO:0005521)
0.0 1.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0005549 odorant binding(GO:0005549)
0.0 3.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.7 GO:0019956 chemokine binding(GO:0019956)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 1.0 GO:0043621 protein self-association(GO:0043621)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 4.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.2 PID ATM PATHWAY ATM pathway
0.0 0.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.6 REACTOME CHROMOSOME MAINTENANCE Genes involved in Chromosome Maintenance
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins