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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for GAGGUAG

Z-value: 1.33

Motif logo

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miRNA associated with seed GAGGUAG

NamemiRBASE accession
hsa-let-7a-5p
MIMAT0000062
hsa-let-7b-5p
MIMAT0000063
hsa-let-7c-5p
MIMAT0000064
hsa-let-7d-5p
MIMAT0000065
hsa-let-7e-5p
MIMAT0000066
hsa-let-7f-5p
MIMAT0000067
hsa-let-7g-5p
MIMAT0000414
hsa-let-7i-5p
MIMAT0000415
hsa-miR-98-5p
MIMAT0000096
hsa-miR-4458
MIMAT0018980
hsa-miR-4500
MIMAT0019036

Activity profile of GAGGUAG motif

Sorted Z-values of GAGGUAG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_25102252 5.76 ENST00000261192.7
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr1_+_152486950 4.93 ENST00000368790.3
CRCT1
cysteine-rich C-terminal 1
chr2_-_1748214 4.35 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN
peroxidasin homolog (Drosophila)
chr12_+_4382917 3.91 ENST00000261254.3
CCND2
cyclin D2
chr19_+_6531010 3.69 ENST00000245817.3
TNFSF9
tumor necrosis factor (ligand) superfamily, member 9
chr1_-_9189229 3.59 ENST00000377411.4
GPR157
G protein-coupled receptor 157
chr9_+_131174024 3.54 ENST00000420034.1
ENST00000372842.1
CERCAM
cerebral endothelial cell adhesion molecule
chr12_+_66217911 3.54 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chrX_-_107681633 3.52 ENST00000394872.2
ENST00000334504.7
COL4A6
collagen, type IV, alpha 6
chr7_-_23510086 3.48 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr21_-_28217721 3.28 ENST00000284984.3
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr1_+_15736359 3.24 ENST00000375980.4
EFHD2
EF-hand domain family, member D2
chr5_+_156887027 3.23 ENST00000435489.2
ENST00000311946.7
NIPAL4
NIPA-like domain containing 4
chr2_-_190044480 2.88 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr15_+_39873268 2.86 ENST00000397591.2
ENST00000260356.5
THBS1
thrombospondin 1
chr20_-_5591626 2.83 ENST00000379019.4
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr12_-_69326940 2.80 ENST00000549781.1
ENST00000548262.1
ENST00000551568.1
ENST00000548954.1
CPM
carboxypeptidase M
chr12_-_85306594 2.77 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr10_+_102106829 2.75 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr13_+_110959598 2.75 ENST00000360467.5
COL4A2
collagen, type IV, alpha 2
chr1_-_28503693 2.73 ENST00000373857.3
PTAFR
platelet-activating factor receptor
chr7_+_100797678 2.61 ENST00000337619.5
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr12_+_1800179 2.48 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr17_+_41476327 2.44 ENST00000320033.4
ARL4D
ADP-ribosylation factor-like 4D
chr5_+_38846101 2.40 ENST00000274276.3
OSMR
oncostatin M receptor
chr1_-_204121013 2.28 ENST00000367201.3
ETNK2
ethanolamine kinase 2
chr11_+_130318869 2.24 ENST00000299164.2
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr6_+_36646435 2.14 ENST00000244741.5
ENST00000405375.1
ENST00000373711.2
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr16_+_2479390 2.03 ENST00000397066.4
CCNF
cyclin F
chr19_+_926000 1.92 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr3_-_52090461 1.91 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr8_-_29208183 1.90 ENST00000240100.2
DUSP4
dual specificity phosphatase 4
chr9_-_72287191 1.88 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr20_-_46415297 1.85 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chr12_+_56915713 1.85 ENST00000262031.5
ENST00000552247.2
RBMS2
RNA binding motif, single stranded interacting protein 2
chr6_+_106546808 1.83 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr2_+_75061108 1.82 ENST00000290573.2
HK2
hexokinase 2
chr3_-_87040233 1.81 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr1_+_203595903 1.77 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr20_+_6748311 1.75 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr1_+_38158090 1.72 ENST00000373055.1
ENST00000327331.2
CDCA8
cell division cycle associated 8
chr18_-_12657988 1.72 ENST00000410092.3
ENST00000409402.4
SPIRE1
spire-type actin nucleation factor 1
chr3_+_49209023 1.70 ENST00000332780.2
KLHDC8B
kelch domain containing 8B
chr6_+_12290586 1.69 ENST00000379375.5
EDN1
endothelin 1
chr5_-_139726181 1.62 ENST00000507104.1
ENST00000230990.6
HBEGF
heparin-binding EGF-like growth factor
chr1_-_153363452 1.60 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr2_+_70142189 1.57 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr12_-_12674032 1.57 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chr3_-_185216766 1.56 ENST00000296254.3
TMEM41A
transmembrane protein 41A
chr7_-_25019760 1.56 ENST00000352860.1
ENST00000353930.1
ENST00000431825.2
ENST00000313367.2
OSBPL3
oxysterol binding protein-like 3
chr13_-_30881621 1.55 ENST00000380615.3
KATNAL1
katanin p60 subunit A-like 1
chrX_+_64887512 1.54 ENST00000360270.5
MSN
moesin
chr2_+_10262442 1.54 ENST00000360566.2
RRM2
ribonucleotide reductase M2
chr19_+_531713 1.51 ENST00000215574.4
CDC34
cell division cycle 34
chr1_+_230202936 1.49 ENST00000366672.4
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr14_-_53162361 1.48 ENST00000395686.3
ERO1L
ERO1-like (S. cerevisiae)
chr6_+_41606176 1.47 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MDFI
MyoD family inhibitor
chr8_-_144623595 1.47 ENST00000262577.5
ZC3H3
zinc finger CCCH-type containing 3
chr13_-_33859819 1.46 ENST00000336934.5
STARD13
StAR-related lipid transfer (START) domain containing 13
chr15_-_45815005 1.46 ENST00000261867.4
SLC30A4
solute carrier family 30 (zinc transporter), member 4
chr10_+_101419187 1.41 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr14_-_35182994 1.41 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr22_+_37447771 1.38 ENST00000402077.3
ENST00000403888.3
ENST00000456470.1
KCTD17
potassium channel tetramerization domain containing 17
chr15_+_74833518 1.37 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr3_-_16306432 1.36 ENST00000383775.4
ENST00000488423.1
DPH3
diphthamide biosynthesis 3
chr1_-_179198702 1.34 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr11_+_119076745 1.32 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr15_+_63481668 1.31 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B
RAB8B, member RAS oncogene family
chr17_-_48278983 1.30 ENST00000225964.5
COL1A1
collagen, type I, alpha 1
chr21_-_42880075 1.30 ENST00000332149.5
TMPRSS2
transmembrane protease, serine 2
chr13_+_52158610 1.25 ENST00000298125.5
WDFY2
WD repeat and FYVE domain containing 2
chr14_+_24867992 1.24 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr5_-_64064508 1.23 ENST00000513458.4
SREK1IP1
SREK1-interacting protein 1
chr11_+_63580855 1.20 ENST00000294244.4
C11orf84
chromosome 11 open reading frame 84
chr6_+_34204642 1.18 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr17_+_1958388 1.18 ENST00000399849.3
HIC1
hypermethylated in cancer 1
chr16_+_447209 1.17 ENST00000382940.4
ENST00000219479.2
NME4
NME/NM23 nucleoside diphosphate kinase 4
chr9_+_128509624 1.16 ENST00000342287.5
ENST00000373487.4
PBX3
pre-B-cell leukemia homeobox 3
chr3_+_150126101 1.13 ENST00000361875.3
ENST00000361136.2
TSC22D2
TSC22 domain family, member 2
chr20_-_48532019 1.13 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr3_+_121774202 1.13 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr6_+_11094266 1.13 ENST00000416247.2
SMIM13
small integral membrane protein 13
chr1_-_24126892 1.11 ENST00000374497.3
ENST00000425913.1
GALE
UDP-galactose-4-epimerase
chr7_+_76090993 1.10 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
DTX2
deltex homolog 2 (Drosophila)
chr1_-_120190396 1.08 ENST00000421812.2
ZNF697
zinc finger protein 697
chr2_+_74881355 1.06 ENST00000357877.2
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr3_+_171758344 1.05 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr15_+_89164520 1.04 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr9_-_77567743 1.03 ENST00000376854.5
C9orf40
chromosome 9 open reading frame 40
chr14_+_75469606 1.03 ENST00000266126.5
EIF2B2
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
chr19_+_14063278 1.02 ENST00000254337.6
DCAF15
DDB1 and CUL4 associated factor 15
chr11_+_69455855 1.01 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr11_-_12030629 1.01 ENST00000396505.2
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr21_-_46131470 1.00 ENST00000323084.4
TSPEAR
thrombospondin-type laminin G domain and EAR repeats
chr17_+_36508111 1.00 ENST00000331159.5
ENST00000577233.1
SOCS7
suppressor of cytokine signaling 7
chr3_-_48229846 0.99 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A
cell division cycle 25A
chr15_+_45879321 0.98 ENST00000220531.3
ENST00000567461.1
BLOC1S6
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr14_+_53019822 0.96 ENST00000321662.6
GPR137C
G protein-coupled receptor 137C
chr19_+_34287751 0.96 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr5_-_131563501 0.96 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr7_-_106301405 0.95 ENST00000523505.1
CCDC71L
coiled-coil domain containing 71-like
chr7_+_120628731 0.94 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr8_+_126442563 0.93 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr17_-_42908155 0.93 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1
gap junction protein, gamma 1, 45kDa
chr5_+_148206156 0.93 ENST00000305988.4
ADRB2
adrenoceptor beta 2, surface
chr3_+_196594727 0.92 ENST00000445299.2
ENST00000323460.5
ENST00000419026.1
SENP5
SUMO1/sentrin specific peptidase 5
chr1_+_12227035 0.92 ENST00000376259.3
ENST00000536782.1
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr2_+_201676256 0.90 ENST00000452206.1
ENST00000410110.2
ENST00000409600.1
BZW1
basic leucine zipper and W2 domains 1
chr19_+_1450112 0.89 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
APC2
adenomatosis polyposis coli 2
chrX_-_54384425 0.89 ENST00000375169.3
ENST00000354646.2
WNK3
WNK lysine deficient protein kinase 3
chr10_+_125425871 0.89 ENST00000284674.1
GPR26
G protein-coupled receptor 26
chr1_-_229478236 0.88 ENST00000366687.1
ENST00000452552.1
CCSAP
centriole, cilia and spindle-associated protein
chr15_+_90544532 0.88 ENST00000268154.4
ZNF710
zinc finger protein 710
chr15_-_51630772 0.88 ENST00000557858.1
ENST00000558328.1
ENST00000396404.4
ENST00000561075.1
ENST00000405011.2
ENST00000559980.1
ENST00000453807.2
ENST00000396402.1
CYP19A1
cytochrome P450, family 19, subfamily A, polypeptide 1
chr9_-_136242909 0.87 ENST00000371991.3
ENST00000545297.1
SURF4
surfeit 4
chr16_-_89007491 0.87 ENST00000327483.5
ENST00000564416.1
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr4_+_84457250 0.87 ENST00000395226.2
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr22_-_39640756 0.87 ENST00000331163.6
PDGFB
platelet-derived growth factor beta polypeptide
chr2_-_230933709 0.86 ENST00000436869.1
ENST00000295190.4
SLC16A14
solute carrier family 16, member 14
chr9_+_118916082 0.85 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr9_+_103189405 0.84 ENST00000395067.2
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr9_+_77703414 0.84 ENST00000346234.6
OSTF1
osteoclast stimulating factor 1
chr7_+_138916231 0.83 ENST00000473989.3
ENST00000288561.8
UBN2
ubinuclein 2
chr19_+_45582453 0.83 ENST00000591607.1
ENST00000591747.1
ENST00000270257.4
ENST00000391951.2
ENST00000587566.1
GEMIN7
MARK4
gem (nuclear organelle) associated protein 7
MAP/microtubule affinity-regulating kinase 4
chr14_+_72399833 0.83 ENST00000553530.1
ENST00000556437.1
RGS6
regulator of G-protein signaling 6
chr6_+_46620676 0.83 ENST00000371347.5
ENST00000411689.2
SLC25A27
solute carrier family 25, member 27
chr14_+_100150622 0.83 ENST00000261835.3
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr22_+_50609150 0.83 ENST00000159647.5
ENST00000395842.2
PANX2
pannexin 2
chr22_+_18043133 0.82 ENST00000327451.6
ENST00000399813.1
SLC25A18
solute carrier family 25 (glutamate carrier), member 18
chr6_+_125283566 0.82 ENST00000521654.2
RNF217
ring finger protein 217
chr3_-_122233723 0.82 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr3_+_102153859 0.82 ENST00000306176.1
ENST00000466937.1
ZPLD1
zona pellucida-like domain containing 1
chr17_+_18218587 0.81 ENST00000406438.3
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr1_+_100731749 0.81 ENST00000370128.4
ENST00000260563.4
RTCA
RNA 3'-terminal phosphate cyclase
chr1_+_167599330 0.79 ENST00000367854.3
ENST00000361496.3
RCSD1
RCSD domain containing 1
chr19_-_51523275 0.79 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr2_+_113403434 0.78 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr6_-_80657292 0.77 ENST00000369816.4
ELOVL4
ELOVL fatty acid elongase 4
chr2_+_113239710 0.77 ENST00000233336.6
TTL
tubulin tyrosine ligase
chr20_-_32700075 0.77 ENST00000374980.2
EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr14_+_32798547 0.77 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr8_-_48651648 0.77 ENST00000408965.3
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr9_-_35115836 0.77 ENST00000378566.1
ENST00000378554.2
ENST00000322813.5
FAM214B
family with sequence similarity 214, member B
chr12_+_88536067 0.76 ENST00000549011.1
ENST00000266712.6
ENST00000551088.1
TMTC3
transmembrane and tetratricopeptide repeat containing 3
chr6_-_31107127 0.76 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr19_-_47975417 0.75 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr7_-_92463210 0.75 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr2_+_30454390 0.74 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
LBH
limb bud and heart development
chr12_+_4918342 0.74 ENST00000280684.3
ENST00000433855.1
KCNA6
potassium voltage-gated channel, shaker-related subfamily, member 6
chr15_+_81293254 0.73 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chrX_+_152907913 0.71 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr1_+_204042723 0.71 ENST00000367204.1
SOX13
SRY (sex determining region Y)-box 13
chr19_+_38810447 0.71 ENST00000263372.3
KCNK6
potassium channel, subfamily K, member 6
chr5_+_150157444 0.71 ENST00000526627.1
SMIM3
small integral membrane protein 3
chr1_-_165325939 0.71 ENST00000342310.3
LMX1A
LIM homeobox transcription factor 1, alpha
chr5_-_172198190 0.69 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr5_+_172261228 0.69 ENST00000393784.3
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr7_+_107220422 0.69 ENST00000005259.4
BCAP29
B-cell receptor-associated protein 29
chr9_-_73029540 0.69 ENST00000377126.2
KLF9
Kruppel-like factor 9
chrX_+_118108571 0.68 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr8_-_134584152 0.68 ENST00000521180.1
ENST00000517668.1
ENST00000319914.5
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr22_+_38093005 0.68 ENST00000406386.3
TRIOBP
TRIO and F-actin binding protein
chr4_+_15004165 0.66 ENST00000538197.1
ENST00000541112.1
ENST00000442003.2
CPEB2
cytoplasmic polyadenylation element binding protein 2
chr1_+_154377669 0.66 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr12_-_95611149 0.66 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chrX_+_16804544 0.65 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr5_-_74326724 0.65 ENST00000322348.4
GCNT4
glucosaminyl (N-acetyl) transferase 4, core 2
chr19_-_14606900 0.65 ENST00000393029.3
ENST00000393028.1
ENST00000393033.4
ENST00000345425.2
ENST00000586027.1
ENST00000591349.1
ENST00000587210.1
GIPC1
GIPC PDZ domain containing family, member 1
chr2_+_234160217 0.65 ENST00000392017.4
ENST00000347464.5
ENST00000444735.1
ENST00000373525.5
ENST00000419681.1
ATG16L1
autophagy related 16-like 1 (S. cerevisiae)
chr3_-_33138286 0.64 ENST00000416695.2
ENST00000342462.4
ENST00000399402.3
TMPPE
GLB1
transmembrane protein with metallophosphoesterase domain
galactosidase, beta 1
chr8_+_24772455 0.64 ENST00000433454.2
NEFM
neurofilament, medium polypeptide
chr3_-_57678772 0.63 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr5_+_150157860 0.63 ENST00000600109.1
AC010441.1
AC010441.1
chr8_-_124553437 0.63 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr14_+_75348592 0.63 ENST00000334220.4
DLST
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr6_-_32157947 0.62 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr11_-_78052923 0.62 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr10_+_18948311 0.62 ENST00000377275.3
ARL5B
ADP-ribosylation factor-like 5B
chr1_-_208417620 0.62 ENST00000367033.3
PLXNA2
plexin A2
chr3_-_185542817 0.61 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr15_-_23086394 0.61 ENST00000337435.4
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr1_-_179846928 0.61 ENST00000367612.3
ENST00000609928.1
TOR1AIP2
torsin A interacting protein 2
chr14_+_55518349 0.60 ENST00000395468.4
MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr9_+_116917807 0.60 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr2_+_121010324 0.60 ENST00000272519.5
RALB
v-ral simian leukemia viral oncogene homolog B
chr22_-_36236265 0.59 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr15_+_83654950 0.59 ENST00000304191.3
FAM103A1
family with sequence similarity 103, member A1
chr3_+_49591881 0.59 ENST00000296452.4
BSN
bassoon presynaptic cytomatrix protein
chr8_+_70378852 0.59 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1
sulfatase 1
chr1_-_84972248 0.58 ENST00000370645.4
ENST00000370641.3
GNG5
guanine nucleotide binding protein (G protein), gamma 5
chr17_-_58469474 0.58 ENST00000300896.4
USP32
ubiquitin specific peptidase 32
chr2_+_153574428 0.58 ENST00000326446.5
ARL6IP6
ADP-ribosylation-like factor 6 interacting protein 6
chrX_-_15353629 0.57 ENST00000333590.4
ENST00000428964.1
ENST00000542278.1
PIGA
phosphatidylinositol glycan anchor biosynthesis, class A
chr6_+_4890226 0.57 ENST00000343762.5
CDYL
chromodomain protein, Y-like
chrX_-_80065146 0.57 ENST00000373275.4
BRWD3
bromodomain and WD repeat domain containing 3
chr12_+_56862301 0.57 ENST00000338146.5
SPRYD4
SPRY domain containing 4
chr9_-_111696340 0.55 ENST00000374647.5
IKBKAP
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr1_+_153232160 0.55 ENST00000368742.3
LOR
loricrin
chr7_+_5229819 0.55 ENST00000288828.4
ENST00000401525.3
ENST00000404704.3
WIPI2
WD repeat domain, phosphoinositide interacting 2
chr3_-_101039402 0.55 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2

Network of associatons between targets according to the STRING database.

First level regulatory network of GAGGUAG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.0 5.8 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
1.0 2.9 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.9 4.7 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.9 3.7 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.9 2.8 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.9 2.7 GO:1904317 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.6 2.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.6 1.8 GO:0098736 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.6 1.7 GO:0060129 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.6 1.7 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.5 1.4 GO:0044691 tooth eruption(GO:0044691)
0.4 2.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.4 1.6 GO:0051541 elastin metabolic process(GO:0051541)
0.4 2.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.4 2.0 GO:0045204 MAPK export from nucleus(GO:0045204)
0.4 0.4 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.4 1.1 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.4 3.0 GO:0035524 proline transmembrane transport(GO:0035524)
0.4 1.8 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.3 0.9 GO:0045659 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.3 0.9 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.3 1.5 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via threonine(GO:0018243)
0.3 0.9 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.3 2.8 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 2.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.3 1.8 GO:1904925 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.3 1.5 GO:0022614 membrane to membrane docking(GO:0022614)
0.3 3.6 GO:0060019 radial glial cell differentiation(GO:0060019)
0.3 3.8 GO:0015693 magnesium ion transport(GO:0015693)
0.3 1.0 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.2 1.7 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.2 1.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 3.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 3.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 0.9 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.2 0.9 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.2 0.4 GO:0002442 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.2 0.7 GO:0002384 hepatic immune response(GO:0002384)
0.2 2.6 GO:0032119 sequestering of zinc ion(GO:0032119)
0.2 0.9 GO:1905176 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.2 0.6 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.2 1.5 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.2 0.8 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 1.4 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 0.6 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.2 0.2 GO:1901205 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205)
0.2 1.3 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.2 3.9 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 0.7 GO:2000035 regulation of stem cell division(GO:2000035)
0.2 0.5 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.2 1.6 GO:0051013 microtubule severing(GO:0051013)
0.2 1.2 GO:0007386 compartment pattern specification(GO:0007386)
0.2 0.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 2.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 0.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 0.8 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.2 0.5 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 0.6 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.2 0.5 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154)
0.1 1.2 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.1 0.9 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 2.0 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 0.7 GO:0030047 actin modification(GO:0030047)
0.1 1.7 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.5 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.4 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.9 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 1.5 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951) positive regulation of inclusion body assembly(GO:0090261)
0.1 1.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.1 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 4.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.4 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 0.8 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.2 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 2.0 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.1 1.2 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.3 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 1.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.8 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 0.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.3 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.7 GO:0051414 response to cortisol(GO:0051414)
0.1 1.2 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 0.5 GO:0090245 somatic muscle development(GO:0007525) axis elongation involved in somitogenesis(GO:0090245)
0.1 1.0 GO:0070141 response to UV-A(GO:0070141)
0.1 0.8 GO:0034214 protein hexamerization(GO:0034214)
0.1 1.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 2.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.4 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.4 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 0.2 GO:1903061 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) positive regulation of protein lipidation(GO:1903061) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.8 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.8 GO:0002176 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.1 0.6 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.4 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 1.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.9 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.4 GO:0014028 notochord formation(GO:0014028)
0.1 0.7 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.4 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.1 0.2 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.1 0.7 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 1.4 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 0.4 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.1 0.4 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.1 1.0 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 2.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.8 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.1 0.2 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.6 GO:0002118 aggressive behavior(GO:0002118)
0.1 0.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 1.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.4 GO:1902715 secretory granule localization(GO:0032252) positive regulation of interferon-gamma secretion(GO:1902715)
0.1 0.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.2 GO:0009644 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.1 0.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.4 GO:0032535 regulation of cellular component size(GO:0032535)
0.1 0.6 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 0.6 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.6 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.5 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1 0.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.5 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.7 GO:0042048 olfactory behavior(GO:0042048)
0.1 0.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.5 GO:0034378 chylomicron assembly(GO:0034378)
0.1 0.3 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.9 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.7 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 3.9 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.4 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 2.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.6 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.6 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.5 GO:0051451 myoblast migration(GO:0051451)
0.0 0.3 GO:0034770 regulation of histone H3-K36 methylation(GO:0000414) histone H4-K20 methylation(GO:0034770)
0.0 0.8 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.1 GO:0060978 angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.5 GO:0015074 DNA integration(GO:0015074)
0.0 0.6 GO:0010225 response to UV-C(GO:0010225)
0.0 0.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.3 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.3 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.5 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.4 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 1.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 1.6 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0034184 regulation of maintenance of sister chromatid cohesion(GO:0034091) positive regulation of maintenance of sister chromatid cohesion(GO:0034093) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 1.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 1.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.8 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.4 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 2.8 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 2.8 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.3 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.1 GO:1902001 fatty acid transmembrane transport(GO:1902001)
0.0 0.3 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.4 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.7 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.3 GO:0016050 vesicle organization(GO:0016050)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 1.0 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.2 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360) Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 0.1 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0030397 mitotic nuclear envelope disassembly(GO:0007077) membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.4 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.4 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 1.3 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.6 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.3 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 1.9 GO:1901800 positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.4 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 1.1 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.4 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.0 GO:0021502 neural fold elevation formation(GO:0021502) negative regulation of mononuclear cell migration(GO:0071676) allantois development(GO:1905069)
0.0 0.5 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.4 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.6 GO:0035418 protein localization to synapse(GO:0035418)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0005588 collagen type V trimer(GO:0005588)
0.8 6.7 GO:0005587 collagen type IV trimer(GO:0005587)
0.8 2.4 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.7 2.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.7 3.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.4 1.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 4.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.4 2.6 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.3 1.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 2.9 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 2.0 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.9 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.2 0.4 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.2 0.5 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 0.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.2 1.5 GO:0051286 cell tip(GO:0051286)
0.1 1.0 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.9 GO:0016342 catenin complex(GO:0016342)
0.1 0.9 GO:0043196 varicosity(GO:0043196)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.3 GO:0016600 flotillin complex(GO:0016600)
0.1 1.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.8 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 1.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.6 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.5 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.6 GO:0005883 neurofilament(GO:0005883)
0.1 0.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.8 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.3 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 1.9 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.2 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.8 GO:0005884 actin filament(GO:0005884)
0.0 0.4 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 4.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.4 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.8 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.7 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 3.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 2.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 2.0 GO:0005795 Golgi stack(GO:0005795)
0.0 0.7 GO:0001726 ruffle(GO:0001726)
0.0 0.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 2.7 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 2.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.8 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.8 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 5.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0000792 heterochromatin(GO:0000792)
0.0 2.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 4.4 GO:0045121 membrane raft(GO:0045121)
0.0 0.3 GO:0030424 axon(GO:0030424)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:1990234 transferase complex(GO:1990234)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.8 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
1.0 2.9 GO:0070052 collagen V binding(GO:0070052)
0.9 2.8 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.9 2.8 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.9 3.5 GO:0035501 MH1 domain binding(GO:0035501)
0.9 4.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.9 2.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.7 2.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.6 1.8 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.6 2.8 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.5 2.7 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.5 2.4 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.3 1.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 0.7 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.3 1.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 4.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 1.1 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.3 0.8 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.3 1.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 0.8 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 0.9 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.2 2.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.2 1.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 1.8 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 0.6 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 1.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 0.8 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.2 0.8 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 1.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 3.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 3.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 0.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 2.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 0.8 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.2 0.6 GO:0016936 galactoside binding(GO:0016936)
0.2 0.6 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 1.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.4 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 1.0 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.4 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.5 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.4 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 2.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.2 GO:1901612 cardiolipin binding(GO:1901612)
0.1 1.3 GO:0030911 TPR domain binding(GO:0030911)
0.1 4.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.4 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 1.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 11.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 1.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.6 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 4.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.9 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.9 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.4 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.2 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 3.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.4 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 1.5 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.7 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.4 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 1.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.4 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 2.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.4 GO:0035197 siRNA binding(GO:0035197)
0.0 0.8 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 1.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.0 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.9 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 2.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 2.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 3.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 1.9 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 2.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.5 GO:0017022 myosin binding(GO:0017022)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 3.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.5 GO:0043531 ADP binding(GO:0043531)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 1.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 12.0 NABA COLLAGENS Genes encoding collagen proteins
0.1 5.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 3.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 3.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 6.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 2.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 3.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.6 PID E2F PATHWAY E2F transcription factor network
0.0 8.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 3.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 4.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID FOXO PATHWAY FoxO family signaling
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 5.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 12.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 2.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 7.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 2.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.7 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.4 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 1.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 2.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 3.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 4.9 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 3.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP