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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for GATA1_GATA4

Z-value: 0.89

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Transcription factors associated with GATA1_GATA4

Gene Symbol Gene ID Gene Info
ENSG00000102145.9 GATA binding protein 1
ENSG00000136574.13 GATA binding protein 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA1hg19_v2_chrX_+_48644962_486449830.551.5e-03Click!
GATA4hg19_v2_chr8_+_11534462_115344750.504.9e-03Click!

Activity profile of GATA1_GATA4 motif

Sorted Z-values of GATA1_GATA4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_102928009 4.91 ENST00000404917.2
ENST00000447231.1
interleukin 1 receptor-like 1
chr1_-_153113927 4.87 ENST00000368752.4
small proline-rich protein 2B
chr9_+_33795533 4.69 ENST00000379405.3
protease, serine, 3
chr1_-_24469602 4.23 ENST00000270800.1
interleukin 22 receptor, alpha 1
chr12_+_4385230 3.86 ENST00000536537.1
cyclin D2
chr4_-_159094194 3.30 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chr19_-_51487071 2.60 ENST00000391807.1
ENST00000593904.1
kallikrein-related peptidase 7
chr4_-_103266355 2.58 ENST00000424970.2
solute carrier family 39 (zinc transporter), member 8
chr19_-_51487282 2.45 ENST00000595820.1
ENST00000597707.1
ENST00000336317.4
kallikrein-related peptidase 7
chrX_+_135278908 2.18 ENST00000539015.1
ENST00000370683.1
four and a half LIM domains 1
chr17_+_74381343 2.18 ENST00000392496.3
sphingosine kinase 1
chr8_+_124194875 2.11 ENST00000522648.1
ENST00000276699.6
family with sequence similarity 83, member A
chr8_+_124194752 2.03 ENST00000318462.6
family with sequence similarity 83, member A
chr1_-_153029980 1.93 ENST00000392653.2
small proline-rich protein 2A
chr3_-_98312548 1.90 ENST00000264193.2
coproporphyrinogen oxidase
chr1_-_153013588 1.85 ENST00000360379.3
small proline-rich protein 2D
chrX_+_135279179 1.82 ENST00000370676.3
four and a half LIM domains 1
chr3_-_47950745 1.66 ENST00000429422.1
microtubule-associated protein 4
chr12_+_15699286 1.58 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
protein tyrosine phosphatase, receptor type, O
chrX_+_56258844 1.54 ENST00000374928.3
Kruppel-like factor 8
chr2_-_165424973 1.53 ENST00000543549.1
growth factor receptor-bound protein 14
chr7_-_99277610 1.52 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
cytochrome P450, family 3, subfamily A, polypeptide 5
chr9_+_139557360 1.47 ENST00000308874.7
ENST00000406555.3
ENST00000492862.2
EGF-like-domain, multiple 7
chr4_-_103266219 1.46 ENST00000394833.2
solute carrier family 39 (zinc transporter), member 8
chr7_+_100547156 1.46 ENST00000379458.4
Protein LOC100131514
chr19_+_10397621 1.45 ENST00000380770.3
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr9_+_34652164 1.43 ENST00000441545.2
ENST00000553620.1
interleukin 11 receptor, alpha
chr19_+_10397648 1.41 ENST00000340992.4
ENST00000393717.2
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr2_+_174219548 1.40 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
cell division cycle associated 7
chr18_+_19749386 1.40 ENST00000269216.3
GATA binding protein 6
chr2_-_24307162 1.38 ENST00000413037.1
ENST00000407482.1
tumor protein p53 inducible protein 3
chr16_+_70680439 1.37 ENST00000288098.2
interleukin 34
chr9_-_114937465 1.37 ENST00000355396.3
sushi domain containing 1
chr4_-_68749745 1.33 ENST00000283916.6
transmembrane protease, serine 11D
chrX_+_152082969 1.32 ENST00000535861.1
ENST00000539731.1
ENST00000449285.2
ENST00000318504.7
ENST00000324823.6
ENST00000370268.4
ENST00000370270.2
zinc finger protein 185 (LIM domain)
chr5_+_159848807 1.27 ENST00000352433.5
pituitary tumor-transforming 1
chr9_-_114937543 1.27 ENST00000374264.2
ENST00000374263.3
sushi domain containing 1
chr5_-_39219705 1.26 ENST00000351578.6
FYN binding protein
chr1_-_94050668 1.26 ENST00000539242.1
breast cancer anti-estrogen resistance 3
chr22_-_20231207 1.22 ENST00000425986.1
reticulon 4 receptor
chr6_+_12290586 1.22 ENST00000379375.5
endothelin 1
chr9_+_33240157 1.20 ENST00000379721.3
serine peptidase inhibitor, Kazal type 4
chr12_-_52845910 1.19 ENST00000252252.3
keratin 6B
chr1_-_153521597 1.18 ENST00000368712.1
S100 calcium binding protein A3
chr17_-_73840415 1.18 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
unc-13 homolog D (C. elegans)
chr7_-_50860565 1.18 ENST00000403097.1
growth factor receptor-bound protein 10
chr15_-_34610962 1.16 ENST00000290209.5
solute carrier family 12 (potassium/chloride transporter), member 6
chr14_+_85996471 1.15 ENST00000330753.4
fibronectin leucine rich transmembrane protein 2
chrX_+_107288239 1.15 ENST00000217957.5
V-set and immunoglobulin domain containing 1
chr17_+_33914276 1.13 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chrX_+_107288197 1.12 ENST00000415430.3
V-set and immunoglobulin domain containing 1
chr1_-_201368653 1.11 ENST00000367313.3
ladinin 1
chr2_+_27719697 1.10 ENST00000264717.2
ENST00000424318.2
glucokinase (hexokinase 4) regulator
chr2_-_69098566 1.09 ENST00000295379.1
bone morphogenetic protein 10
chr9_-_114937676 1.08 ENST00000374270.3
sushi domain containing 1
chr4_-_68749699 1.06 ENST00000545541.1
transmembrane protease, serine 11D
chr5_-_39270725 1.05 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYN binding protein
chr1_-_201368707 1.05 ENST00000391967.2
ladinin 1
chr5_-_39219641 1.03 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYN binding protein
chrX_+_44703249 1.02 ENST00000339042.4
dual specificity phosphatase 21
chr9_+_132099158 1.01 ENST00000444125.1
RP11-65J3.1
chr7_+_142457315 1.01 ENST00000486171.1
ENST00000311737.7
protease, serine, 1 (trypsin 1)
chr1_-_204116078 1.01 ENST00000367198.2
ENST00000452983.1
ethanolamine kinase 2
chrX_+_38211777 1.00 ENST00000039007.4
ornithine carbamoyltransferase
chr12_+_4430371 0.99 ENST00000179259.4
chromosome 12 open reading frame 5
chr1_-_153521714 0.97 ENST00000368713.3
S100 calcium binding protein A3
chr3_+_172468505 0.94 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
epithelial cell transforming sequence 2 oncogene
chr10_+_71075552 0.92 ENST00000298649.3
hexokinase 1
chr6_-_131277510 0.92 ENST00000525193.1
ENST00000527659.1
erythrocyte membrane protein band 4.1-like 2
chr14_-_94421923 0.92 ENST00000555507.1
ankyrin repeat and SOCS box containing 2
chr4_-_120243545 0.91 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr18_+_61445007 0.91 ENST00000447428.1
ENST00000546027.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr6_-_107235287 0.90 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1
chr8_-_91095099 0.90 ENST00000265431.3
calbindin 1, 28kDa
chr17_+_1958388 0.90 ENST00000399849.3
hypermethylated in cancer 1
chr11_-_125550764 0.90 ENST00000527795.1
acrosomal vesicle protein 1
chr5_+_147443534 0.89 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
serine peptidase inhibitor, Kazal type 5
chr2_-_228028829 0.87 ENST00000396625.3
ENST00000329662.7
collagen, type IV, alpha 4
chr2_+_192543153 0.86 ENST00000425611.2
nucleic acid binding protein 1
chr7_+_139528952 0.86 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
thromboxane A synthase 1 (platelet)
chr17_+_19314505 0.85 ENST00000461366.1
ring finger protein 112
chr7_-_107443652 0.83 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
solute carrier family 26 (anion exchanger), member 3
chrX_+_99899180 0.83 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr11_-_3859089 0.82 ENST00000396979.1
ras homolog family member G
chr6_+_47666275 0.80 ENST00000327753.3
ENST00000283303.2
G protein-coupled receptor 115
chr2_+_201994569 0.79 ENST00000457277.1
CASP8 and FADD-like apoptosis regulator
chr15_-_34628951 0.79 ENST00000397707.2
ENST00000560611.1
solute carrier family 12 (potassium/chloride transporter), member 6
chr19_-_51522955 0.79 ENST00000358789.3
kallikrein-related peptidase 10
chrX_-_65253506 0.78 ENST00000427538.1
V-set and immunoglobulin domain containing 4
chr15_-_74501360 0.78 ENST00000323940.5
stimulated by retinoic acid 6
chr8_+_70404996 0.78 ENST00000402687.4
ENST00000419716.3
sulfatase 1
chr1_+_25598872 0.78 ENST00000328664.4
Rh blood group, D antigen
chr15_+_42066740 0.78 ENST00000514566.1
mitogen-activated protein kinase binding protein 1
chr18_+_21452804 0.78 ENST00000269217.6
laminin, alpha 3
chr12_+_9144626 0.73 ENST00000543895.1
killer cell lectin-like receptor subfamily G, member 1
chr11_-_124311054 0.73 ENST00000328064.2
olfactory receptor, family 8, subfamily B, member 8
chr2_+_201994208 0.73 ENST00000440180.1
CASP8 and FADD-like apoptosis regulator
chr11_-_125550726 0.72 ENST00000315608.3
ENST00000530048.1
acrosomal vesicle protein 1
chr7_-_23510086 0.71 ENST00000258729.3
insulin-like growth factor 2 mRNA binding protein 3
chr19_-_51568324 0.71 ENST00000595547.1
ENST00000335422.3
ENST00000595793.1
ENST00000596955.1
kallikrein-related peptidase 13
chr10_+_5566916 0.70 ENST00000315238.1
calmodulin-like 3
chr10_+_118305435 0.70 ENST00000369221.2
pancreatic lipase
chr11_-_59612969 0.70 ENST00000541311.1
ENST00000257248.2
gastric intrinsic factor (vitamin B synthesis)
chr12_+_9102632 0.70 ENST00000539240.1
killer cell lectin-like receptor subfamily G, member 1
chr1_-_167487758 0.69 ENST00000362089.5
CD247 molecule
chr13_+_31309645 0.69 ENST00000380490.3
arachidonate 5-lipoxygenase-activating protein
chr20_-_54967187 0.69 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
aurora kinase A
chr1_+_209859510 0.69 ENST00000367028.2
ENST00000261465.1
hydroxysteroid (11-beta) dehydrogenase 1
chr12_+_53662073 0.68 ENST00000553219.1
ENST00000257934.4
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr10_+_52152766 0.68 ENST00000596442.1
Uncharacterized protein
chr19_-_51523275 0.67 ENST00000309958.3
kallikrein-related peptidase 10
chr12_-_10022735 0.66 ENST00000228438.2
C-type lectin domain family 2, member B
chr4_-_52883786 0.66 ENST00000343457.3
leucine rich repeat containing 66
chrX_+_48380205 0.65 ENST00000446158.1
ENST00000414061.1
emopamil binding protein (sterol isomerase)
chr2_+_28618532 0.65 ENST00000545753.1
FOS-like antigen 2
chr4_-_143227088 0.64 ENST00000511838.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr14_-_85996332 0.64 ENST00000380722.1
RP11-497E19.1
chr12_+_53662110 0.63 ENST00000552462.1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr19_-_41934635 0.62 ENST00000321702.2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr1_-_205912577 0.61 ENST00000367135.3
ENST00000367134.2
solute carrier family 26 (anion exchanger), member 9
chr5_+_159848854 0.61 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr6_+_167704838 0.61 ENST00000366829.2
unc-93 homolog A (C. elegans)
chr2_+_197504278 0.61 ENST00000272831.7
ENST00000389175.4
ENST00000472405.2
ENST00000423093.2
coiled-coil domain containing 150
chr4_-_48082192 0.60 ENST00000507351.1
TXK tyrosine kinase
chr1_-_226187013 0.60 ENST00000272091.7
SDE2 telomere maintenance homolog (S. pombe)
chr2_-_106054952 0.60 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
four and a half LIM domains 2
chr14_-_81893734 0.59 ENST00000555447.1
stonin 2
chr7_+_155090271 0.59 ENST00000476756.1
insulin induced gene 1
chr17_-_64225508 0.59 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr20_+_34713312 0.58 ENST00000373946.3
erythrocyte membrane protein band 4.1-like 1
chr12_+_75874984 0.58 ENST00000550491.1
GLI pathogenesis-related 1
chr2_+_210517895 0.57 ENST00000447185.1
microtubule-associated protein 2
chr3_+_101818088 0.57 ENST00000491959.1
zona pellucida-like domain containing 1
chr19_-_36822595 0.57 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
long intergenic non-protein coding RNA 665
chr17_+_46537697 0.57 ENST00000579972.1
RP11-433M22.2
chr1_+_115572415 0.56 ENST00000256592.1
thyroid stimulating hormone, beta
chr10_-_71993176 0.56 ENST00000373232.3
pyrophosphatase (inorganic) 1
chr19_-_51017881 0.56 ENST00000601207.1
ENST00000598657.1
ENST00000376916.3
aspartate dehydrogenase domain containing
chr1_-_225616515 0.56 ENST00000338179.2
ENST00000425080.1
lamin B receptor
chr14_-_24584138 0.56 ENST00000558280.1
ENST00000561028.1
neural retina leucine zipper
chr1_-_25747283 0.55 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
Rh blood group, CcEe antigens
chr15_+_67418047 0.55 ENST00000540846.2
SMAD family member 3
chr10_-_48416849 0.55 ENST00000249598.1
growth differentiation factor 2
chr1_+_192127578 0.55 ENST00000367460.3
regulator of G-protein signaling 18
chr15_+_42066632 0.55 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
mitogen-activated protein kinase binding protein 1
chr6_+_31691121 0.55 ENST00000480039.1
ENST00000375810.4
ENST00000375805.2
ENST00000375809.3
ENST00000375804.2
ENST00000375814.3
ENST00000375806.2
chromosome 6 open reading frame 25
chr2_-_231825668 0.54 ENST00000392039.2
G protein-coupled receptor 55
chr1_-_155270770 0.54 ENST00000392414.3
pyruvate kinase, liver and RBC
chr1_-_159880159 0.53 ENST00000599780.1
HCG1995379; Uncharacterized protein
chr11_+_128563652 0.53 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr6_+_167704798 0.53 ENST00000230256.3
unc-93 homolog A (C. elegans)
chr1_+_35247859 0.53 ENST00000373362.3
gap junction protein, beta 3, 31kDa
chr12_-_68647281 0.53 ENST00000328087.4
ENST00000538666.1
interleukin 22
chr8_+_27629459 0.53 ENST00000523566.1
establishment of sister chromatid cohesion N-acetyltransferase 2
chr14_+_60975644 0.53 ENST00000327720.5
SIX homeobox 6
chr19_+_6739662 0.53 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
thyroid hormone receptor interactor 10
chr1_-_175162048 0.53 ENST00000444639.1
KIAA0040
chr13_+_32313658 0.52 ENST00000380314.1
ENST00000298386.2
relaxin/insulin-like family peptide receptor 2
chr8_-_133123406 0.52 ENST00000434736.2
HERV-H LTR-associating 1
chr1_+_207038699 0.52 ENST00000367098.1
interleukin 20
chr8_-_15095832 0.52 ENST00000382080.1
sarcoglycan, zeta
chr1_-_167487808 0.51 ENST00000392122.3
CD247 molecule
chr7_+_123295861 0.51 ENST00000458573.2
ENST00000456238.2
leiomodin 2 (cardiac)
chr5_+_131409476 0.51 ENST00000296871.2
colony stimulating factor 2 (granulocyte-macrophage)
chr15_+_74165945 0.51 ENST00000535547.2
ENST00000300504.2
ENST00000562056.1
TBC1 domain family, member 21
chr6_-_112194484 0.51 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN oncogene related to SRC, FGR, YES
chr4_-_65275162 0.50 ENST00000381210.3
ENST00000507440.1
trans-2,3-enoyl-CoA reductase-like
chr1_+_25599018 0.50 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
Rh blood group, D antigen
chr2_+_201994042 0.50 ENST00000417748.1
CASP8 and FADD-like apoptosis regulator
chr12_-_10324716 0.50 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
oxidized low density lipoprotein (lectin-like) receptor 1
chrX_-_55057403 0.50 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
aminolevulinate, delta-, synthase 2
chr2_-_8464760 0.50 ENST00000430192.1
long intergenic non-protein coding RNA 299
chr21_+_39628852 0.49 ENST00000398938.2
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_150954493 0.49 ENST00000368947.4
annexin A9
chr17_-_57229155 0.49 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr17_+_37824217 0.49 ENST00000394246.1
phenylethanolamine N-methyltransferase
chrX_-_24665353 0.48 ENST00000379144.2
phosphate cytidylyltransferase 1, choline, beta
chr2_+_220436917 0.48 ENST00000243786.2
inhibin, alpha
chr14_-_72458326 0.48 ENST00000542853.1
AC005477.1
chr2_-_14541060 0.48 ENST00000418420.1
ENST00000417751.1
long intergenic non-protein coding RNA 276
chr1_-_214638146 0.48 ENST00000543945.1
protein tyrosine phosphatase, non-receptor type 14
chr3_-_194188956 0.47 ENST00000256031.4
ENST00000446356.1
ATPase type 13A3
chr7_+_76139741 0.47 ENST00000334348.3
ENST00000419923.2
ENST00000448265.3
ENST00000443097.2
uroplakin 3B
chr22_-_29784519 0.47 ENST00000357586.2
ENST00000356015.2
ENST00000432560.2
ENST00000317368.7
adaptor-related protein complex 1, beta 1 subunit
chr10_-_25241499 0.46 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
phosphoribosyl transferase domain containing 1
chr2_+_90077680 0.46 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr5_-_76788317 0.46 ENST00000296679.4
WD repeat domain 41
chr2_+_234600253 0.46 ENST00000373424.1
ENST00000441351.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr17_+_4853442 0.45 ENST00000522301.1
enolase 3 (beta, muscle)
chr6_-_107235331 0.45 ENST00000433965.1
ENST00000430094.1
RP1-60O19.1
chr11_-_19262486 0.45 ENST00000250024.4
E2F transcription factor 8
chr4_+_74606223 0.45 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr6_+_126661253 0.45 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
centromere protein W
chr20_+_42984330 0.44 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
hepatocyte nuclear factor 4, alpha
chr15_-_30113676 0.44 ENST00000400011.2
tight junction protein 1
chr1_+_50574585 0.44 ENST00000371824.1
ENST00000371823.4
ELAV like neuron-specific RNA binding protein 4
chr6_-_35765088 0.44 ENST00000259938.2
colipase, pancreatic
chr2_-_30144432 0.44 ENST00000389048.3
anaplastic lymphoma receptor tyrosine kinase
chr9_-_127269661 0.44 ENST00000373588.4
nuclear receptor subfamily 5, group A, member 1
chr10_+_33271469 0.44 ENST00000414157.1
RP11-462L8.1

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA1_GATA4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.9 GO:0002786 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.8 5.0 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.7 2.2 GO:0046521 sphingoid catabolic process(GO:0046521)
0.5 1.6 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.5 1.4 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.4 1.2 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.4 1.9 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.4 4.0 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.3 1.0 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.3 1.3 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.3 1.3 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.3 1.7 GO:0051012 microtubule sliding(GO:0051012)
0.3 2.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.3 0.8 GO:0060752 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.3 1.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.2 1.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 0.7 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.2 0.9 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 1.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 6.5 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 2.1 GO:0051597 response to methylmercury(GO:0051597)
0.2 0.8 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2 1.0 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.2 0.6 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 0.8 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.2 0.8 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 1.0 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.6 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2 1.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 0.9 GO:0061143 alveolar primary septum development(GO:0061143)
0.2 0.2 GO:0002652 regulation of tolerance induction dependent upon immune response(GO:0002652)
0.2 0.7 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.2 0.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 0.5 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.2 0.6 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 3.9 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.4 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.4 GO:0001897 cytolysis by symbiont of host cells(GO:0001897) hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.6 GO:0071344 diphosphate metabolic process(GO:0071344)
0.1 0.6 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.7 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.5 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.4 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 1.4 GO:0019532 oxalate transport(GO:0019532)
0.1 0.6 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.9 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.3 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 1.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.9 GO:0072205 metanephric collecting duct development(GO:0072205)
0.1 0.2 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 0.4 GO:0036269 swimming behavior(GO:0036269)
0.1 0.4 GO:0007538 primary sex determination(GO:0007538)
0.1 1.1 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 1.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 0.3 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.6 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.6 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 1.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 1.4 GO:0043320 natural killer cell degranulation(GO:0043320)
0.1 0.4 GO:0051891 positive regulation of cardioblast differentiation(GO:0051891)
0.1 0.3 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.5 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.1 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 11.3 GO:0070268 cornification(GO:0070268)
0.1 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.3 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.2 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.1 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.2 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 1.4 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.1 1.6 GO:0044241 lipid digestion(GO:0044241)
0.1 1.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 3.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.4 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.2 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.7 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 1.2 GO:0048681 neuronal signal transduction(GO:0023041) negative regulation of axon regeneration(GO:0048681)
0.1 0.3 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.8 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.2 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.4 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 0.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.4 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.3 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 1.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.3 GO:2001027 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.2 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.3 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.7 GO:0034378 chylomicron assembly(GO:0034378)
0.1 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.5 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.2 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) renal water absorption(GO:0070295)
0.1 0.9 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.2 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.3 GO:1990523 bone regeneration(GO:1990523)
0.1 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.3 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.3 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.8 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 1.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.2 GO:1904346 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.1 0.5 GO:0010629 negative regulation of gene expression(GO:0010629)
0.1 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 1.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 4.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.9 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.8 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.5 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 3.5 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.4 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.8 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 1.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.7 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 2.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.3 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.5 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.4 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.5 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.0 1.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 1.9 GO:2000816 negative regulation of sister chromatid segregation(GO:0033046) negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 1.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.8 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.3 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.2 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.4 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.8 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0070970 positive regulation of interleukin-2 biosynthetic process(GO:0045086) interleukin-2 secretion(GO:0070970)
0.0 0.6 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 1.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) negative regulation of calcium-transporting ATPase activity(GO:1901895) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.2 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.7 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.4 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.5 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.8 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 2.1 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 1.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.4 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.0 0.1 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.0 0.6 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 1.8 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.8 GO:0045687 positive regulation of glial cell differentiation(GO:0045687)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.0 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.5 GO:0061621 NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.5 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0019058 viral life cycle(GO:0019058)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.4 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.1 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.0 0.5 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.9 GO:0006739 NADP metabolic process(GO:0006739)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 1.0 GO:0007566 embryo implantation(GO:0007566)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 3.5 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0070627 ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.5 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0001765 membrane raft assembly(GO:0001765)
0.0 0.1 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.6 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.0 GO:0035377 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.2 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.4 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.6 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.0 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.9 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:0097421 liver regeneration(GO:0097421)
0.0 0.3 GO:0001501 skeletal system development(GO:0001501)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.2 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.2 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.2 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.8 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.5 GO:0006953 acute-phase response(GO:0006953)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.9 GO:0097209 epidermal lamellar body(GO:0097209)
0.6 3.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 1.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 0.9 GO:0097149 centralspindlin complex(GO:0097149)
0.2 0.7 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 0.9 GO:0070876 SOSS complex(GO:0070876)
0.2 0.7 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.2 0.5 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 0.6 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.2 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.0 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 2.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 1.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 7.7 GO:0001533 cornified envelope(GO:0001533)
0.1 0.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:0097679 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.1 0.9 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.3 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 1.1 GO:0008091 spectrin(GO:0008091)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.3 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 1.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.3 GO:1990246 uniplex complex(GO:1990246)
0.1 0.4 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467) 3M complex(GO:1990393)
0.1 1.1 GO:0036020 endolysosome membrane(GO:0036020)
0.0 4.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.1 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.8 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.9 GO:0031105 septin complex(GO:0031105)
0.0 3.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.6 GO:0042627 chylomicron(GO:0042627)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.4 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 1.4 GO:0016235 aggresome(GO:0016235)
0.0 1.4 GO:0031672 A band(GO:0031672)
0.0 0.1 GO:0036027 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.1 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.6 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 2.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 3.1 GO:0043197 dendritic spine(GO:0043197)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.0 GO:0005775 vacuolar lumen(GO:0005775)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 4.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 7.1 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.7 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.7 4.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.4 1.3 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.4 1.2 GO:0038131 neuregulin receptor activity(GO:0038131)
0.4 2.2 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.3 0.9 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.3 0.9 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.3 0.8 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.2 1.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 1.5 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.2 0.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 0.9 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 0.7 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 3.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 0.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 1.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 1.0 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 0.9 GO:0005499 vitamin D binding(GO:0005499)
0.2 0.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.9 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 1.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 0.5 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.2 1.5 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.2 0.6 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 0.9 GO:0004882 androgen receptor activity(GO:0004882)
0.2 0.9 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.9 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.6 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 1.7 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.5 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 3.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.0 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 2.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.9 GO:0042731 PH domain binding(GO:0042731)
0.1 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.5 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 2.6 GO:0005123 death receptor binding(GO:0005123) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.2 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 0.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 1.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.5 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.1 GO:0030172 troponin C binding(GO:0030172)
0.1 2.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.7 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 1.1 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.1 0.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.2 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 0.2 GO:0031768 ghrelin receptor binding(GO:0031768)
0.0 15.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.1 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.6 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 1.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 3.0 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 1.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 2.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0019864 IgG binding(GO:0019864)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 1.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 2.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 3.5 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 1.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 1.4 GO:0005507 copper ion binding(GO:0005507)
0.0 0.4 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 1.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.4 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 16.3 GO:0005198 structural molecule activity(GO:0005198)
0.0 2.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.0 GO:0015265 urea transmembrane transporter activity(GO:0015204) urea channel activity(GO:0015265) amide transmembrane transporter activity(GO:0042887)
0.0 0.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.5 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.2 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.8 GO:0019838 growth factor binding(GO:0019838)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.5 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 3.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 5.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 1.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.3 PID INSULIN PATHWAY Insulin Pathway
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 3.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 6.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.7 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 7.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.9 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 3.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 3.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 1.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 3.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 2.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 4.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 2.0 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 2.5 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 0.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 2.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.8 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 2.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.8 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.5 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.6 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.1 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events