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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for GAUUGUC

Z-value: 0.82

Motif logo

miRNA associated with seed GAUUGUC

NamemiRBASE accession
MIMAT0000276
MIMAT0019945
MIMAT0027433

Activity profile of GAUUGUC motif

Sorted Z-values of GAUUGUC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_5914213 6.09 ENST00000222125.5
ENST00000452990.2
ENST00000588865.1
calcyphosine
chr1_-_207119738 5.22 ENST00000356495.4
polymeric immunoglobulin receptor
chr6_+_17281573 4.62 ENST00000379052.5
RNA binding motif protein 24
chr7_-_131241361 4.62 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
podocalyxin-like
chr4_+_75858290 4.00 ENST00000513238.1
prostate androgen-regulated mucin-like protein 1
chr18_-_45663666 3.50 ENST00000535628.2
zinc finger and BTB domain containing 7C
chr5_+_50678921 2.38 ENST00000230658.7
ISL LIM homeobox 1
chr1_+_244214577 2.09 ENST00000358704.4
zinc finger and BTB domain containing 18
chr19_-_14316980 2.03 ENST00000361434.3
ENST00000340736.6
latrophilin 1
chr7_+_3340989 1.99 ENST00000404826.2
ENST00000389531.3
sidekick cell adhesion molecule 1
chr17_+_68165657 1.97 ENST00000243457.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr4_-_23891693 1.81 ENST00000264867.2
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr16_-_19896220 1.78 ENST00000562469.1
ENST00000300571.2
G protein-coupled receptor, family C, group 5, member B
chr1_+_180601139 1.64 ENST00000367590.4
ENST00000367589.3
xenotropic and polytropic retrovirus receptor 1
chr4_-_105416039 1.60 ENST00000394767.2
CXXC finger protein 4
chr17_+_31254892 1.54 ENST00000394642.3
ENST00000579849.1
transmembrane protein 98
chr12_-_56652111 1.54 ENST00000267116.7
ankyrin repeat domain 52
chr14_+_74111578 1.42 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
dynein, axonemal, light chain 1
chr1_-_86043921 1.42 ENST00000535924.2
dimethylarginine dimethylaminohydrolase 1
chr6_+_167412665 1.36 ENST00000366847.4
FGFR1 oncogene partner
chr1_+_110082487 1.33 ENST00000527748.1
G protein-coupled receptor 61
chr5_+_139027877 1.31 ENST00000302517.3
CXXC finger protein 5
chr1_-_115632035 1.29 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
tetraspanin 2
chr15_+_57668695 1.28 ENST00000281282.5
cingulin-like 1
chr5_+_142149955 1.03 ENST00000378004.3
Rho GTPase activating protein 26
chr12_+_8234807 1.02 ENST00000339754.5
NECAP endocytosis associated 1
chr11_+_123396528 1.00 ENST00000322282.7
ENST00000529750.1
GRAM domain containing 1B
chr3_-_18466787 1.00 ENST00000338745.6
ENST00000450898.1
SATB homeobox 1
chr1_+_61547894 0.98 ENST00000403491.3
nuclear factor I/A
chr15_-_61521495 0.92 ENST00000335670.6
RAR-related orphan receptor A
chr22_-_21213029 0.91 ENST00000572273.1
ENST00000255882.6
phosphatidylinositol 4-kinase, catalytic, alpha
chr7_+_21467642 0.91 ENST00000222584.3
ENST00000432066.2
Sp4 transcription factor
chr6_+_107811162 0.91 ENST00000317357.5
sine oculis binding protein homolog (Drosophila)
chr8_-_72268889 0.89 ENST00000388742.4
eyes absent homolog 1 (Drosophila)
chr6_+_72596604 0.88 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
regulating synaptic membrane exocytosis 1
chr1_-_213189108 0.87 ENST00000535388.1
angel homolog 2 (Drosophila)
chr13_+_108870714 0.84 ENST00000375898.3
abhydrolase domain containing 13
chr3_-_114790179 0.83 ENST00000462705.1
zinc finger and BTB domain containing 20
chr16_+_57126428 0.83 ENST00000290776.8
copine II
chr22_+_31518938 0.82 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
inositol polyphosphate-5-phosphatase J
chr3_-_53080047 0.78 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
Scm-like with four mbt domains 1
chr16_-_68482440 0.77 ENST00000219334.5
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr17_+_58755184 0.76 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
breast carcinoma amplified sequence 3
chr5_+_112312416 0.75 ENST00000389063.2
decapping mRNA 2
chr10_+_20105157 0.74 ENST00000377242.3
ENST00000377252.4
plexin domain containing 2
chr1_-_205782304 0.74 ENST00000367137.3
solute carrier family 41 (magnesium transporter), member 1
chr20_-_31071239 0.74 ENST00000359676.5
chromosome 20 open reading frame 112
chr12_-_42538657 0.74 ENST00000398675.3
glucoside xylosyltransferase 1
chr3_+_137906109 0.74 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
armadillo repeat containing 8
chr3_+_187930719 0.73 ENST00000312675.4
LIM domain containing preferred translocation partner in lipoma
chr2_-_148778258 0.69 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
origin recognition complex, subunit 4
chrX_+_16964794 0.69 ENST00000357277.3
RALBP1 associated Eps domain containing 2
chr7_-_138666053 0.67 ENST00000440172.1
ENST00000422774.1
KIAA1549
chr20_-_50419055 0.67 ENST00000217086.4
spalt-like transcription factor 4
chr21_+_44394620 0.66 ENST00000291547.5
PBX/knotted 1 homeobox 1
chr11_-_86666427 0.65 ENST00000531380.1
frizzled family receptor 4
chr1_-_212004090 0.65 ENST00000366997.4
lysophosphatidylglycerol acyltransferase 1
chr15_+_89631381 0.64 ENST00000352732.5
abhydrolase domain containing 2
chr6_+_33387868 0.63 ENST00000418600.2
synaptic Ras GTPase activating protein 1
chr2_+_24714729 0.63 ENST00000406961.1
ENST00000405141.1
nuclear receptor coactivator 1
chr17_-_66287257 0.63 ENST00000327268.4
solute carrier family 16, member 6
chr9_+_115983808 0.61 ENST00000374210.6
ENST00000374212.4
solute carrier family 31 (copper transporter), member 1
chr13_+_100258907 0.61 ENST00000376355.3
ENST00000376360.1
ENST00000444838.2
ENST00000376354.1
ENST00000339105.4
citrate lyase beta like
chr16_+_69796209 0.60 ENST00000359154.2
ENST00000561780.1
ENST00000563659.1
ENST00000448661.1
WW domain containing E3 ubiquitin protein ligase 2
chr11_-_72853091 0.59 ENST00000311172.7
ENST00000409314.1
FCH and double SH3 domains 2
chr9_-_127905736 0.58 ENST00000336505.6
ENST00000373549.4
suppressor of cancer cell invasion
chr15_+_44719394 0.56 ENST00000260327.4
ENST00000396780.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr9_-_126030817 0.56 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
spermatid perinuclear RNA binding protein
chr2_-_222436988 0.53 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPH receptor A4
chr12_-_49449107 0.52 ENST00000301067.7
lysine (K)-specific methyltransferase 2D
chr7_+_139026057 0.52 ENST00000541515.3
LUC7-like 2 (S. cerevisiae)
chr11_-_130184555 0.50 ENST00000525842.1
zinc finger and BTB domain containing 44
chr10_-_94003003 0.50 ENST00000412050.4
cytoplasmic polyadenylation element binding protein 3
chr19_-_17414179 0.49 ENST00000594194.1
ENST00000247706.3
abhydrolase domain containing 8
chr6_+_42749759 0.49 ENST00000314073.5
GLTSCR1-like
chr6_-_36842784 0.48 ENST00000373699.5
peptidylprolyl isomerase (cyclophilin)-like 1
chr1_-_84464780 0.46 ENST00000260505.8
tubulin tyrosine ligase-like family, member 7
chrX_-_135333722 0.46 ENST00000316077.9
MAP7 domain containing 3
chr12_-_105630016 0.46 ENST00000258530.3
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr20_-_8000426 0.45 ENST00000527925.1
ENST00000246024.2
thioredoxin-related transmembrane protein 4
chr11_-_30038490 0.44 ENST00000328224.6
potassium voltage-gated channel, shaker-related subfamily, member 4
chr3_+_69812877 0.44 ENST00000457080.1
ENST00000328528.6
microphthalmia-associated transcription factor
chr3_+_29322803 0.43 ENST00000396583.3
ENST00000383767.2
RNA binding motif, single stranded interacting protein 3
chr17_+_38219063 0.41 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
thyroid hormone receptor, alpha
chr16_-_87525651 0.41 ENST00000268616.4
zinc finger, CCHC domain containing 14
chr5_-_107717058 0.40 ENST00000359660.5
F-box and leucine-rich repeat protein 17
chr4_+_108745711 0.39 ENST00000394684.4
sphingomyelin synthase 2
chr9_-_35749162 0.39 ENST00000378094.4
ENST00000378103.3
glucosidase, beta (bile acid) 2
chr18_+_905104 0.39 ENST00000579794.1
adenylate cyclase activating polypeptide 1 (pituitary)
chr8_+_104033277 0.38 ENST00000518857.1
ENST00000395862.3
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr1_+_29563011 0.38 ENST00000345512.3
ENST00000373779.3
ENST00000356870.3
ENST00000323874.8
ENST00000428026.2
ENST00000460170.2
protein tyrosine phosphatase, receptor type, U
chr3_-_125094093 0.37 ENST00000484491.1
ENST00000492394.1
ENST00000471196.1
ENST00000468369.1
ENST00000544464.1
ENST00000485866.1
ENST00000360647.4
zinc finger protein 148
chr16_+_85646763 0.36 ENST00000411612.1
ENST00000253458.7
Gse1 coiled-coil protein
chr2_-_20251744 0.36 ENST00000175091.4
lysosomal protein transmembrane 4 alpha
chr1_-_31230650 0.35 ENST00000294507.3
lysosomal protein transmembrane 5
chr10_-_75173785 0.35 ENST00000535178.1
ENST00000372921.5
ENST00000372919.4
annexin A7
chr8_-_71316021 0.32 ENST00000452400.2
nuclear receptor coactivator 2
chr9_-_125027079 0.32 ENST00000417201.3
RNA binding motif protein 18
chr5_-_76935513 0.31 ENST00000306422.3
orthopedia homeobox
chr11_-_124806297 0.31 ENST00000298251.4
hepatic and glial cell adhesion molecule
chr5_-_14871866 0.30 ENST00000284268.6
ANKH inorganic pyrophosphate transport regulator
chr6_-_86352642 0.30 ENST00000355238.6
synaptotagmin binding, cytoplasmic RNA interacting protein
chr3_+_43328004 0.30 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNF related kinase
chr6_+_56954867 0.28 ENST00000370708.4
ENST00000370702.1
zinc finger protein 451
chr12_+_65004292 0.28 ENST00000542104.1
ENST00000336061.2
Ras association (RalGDS/AF-6) domain family member 3
chr12_+_94542459 0.27 ENST00000258526.4
plexin C1
chr4_+_57774042 0.27 ENST00000309042.7
RE1-silencing transcription factor
chr6_-_107436473 0.27 ENST00000369042.1
BEN domain containing 3
chr22_-_47134077 0.27 ENST00000541677.1
ENST00000216264.8
ceramide kinase
chr3_+_137483579 0.26 ENST00000306087.1
SRY (sex determining region Y)-box 14
chr1_+_167190066 0.25 ENST00000367866.2
ENST00000429375.2
ENST00000452019.1
ENST00000420254.3
ENST00000541643.3
POU class 2 homeobox 1
chr1_+_160085501 0.25 ENST00000361216.3
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr2_+_198365122 0.25 ENST00000604458.1
HSPE1-MOB4 readthrough
chr1_-_155532484 0.25 ENST00000368346.3
ENST00000548830.1
ash1 (absent, small, or homeotic)-like (Drosophila)
chr15_+_52043758 0.25 ENST00000249700.4
ENST00000539962.2
tropomodulin 2 (neuronal)
chr5_-_56247935 0.24 ENST00000381199.3
ENST00000381226.3
ENST00000381213.3
mesoderm induction early response 1, family member 3
chr5_-_59189545 0.24 ENST00000340635.6
phosphodiesterase 4D, cAMP-specific
chr7_-_5463175 0.23 ENST00000399537.4
ENST00000430969.1
trinucleotide repeat containing 18
chr3_+_14989076 0.22 ENST00000413118.1
ENST00000425241.1
nuclear receptor subfamily 2, group C, member 2
chr3_-_79068594 0.22 ENST00000436010.2
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr19_-_55690758 0.22 ENST00000590851.1
synaptotagmin V
chr6_-_16761678 0.21 ENST00000244769.4
ENST00000436367.1
ataxin 1
chr12_+_72666407 0.21 ENST00000261180.4
thyrotropin-releasing hormone degrading enzyme
chr21_+_45285050 0.21 ENST00000291572.8
1-acylglycerol-3-phosphate O-acyltransferase 3
chr19_+_3359561 0.21 ENST00000589123.1
ENST00000346156.5
ENST00000395111.3
ENST00000586919.1
nuclear factor I/C (CCAAT-binding transcription factor)
chr4_+_48343339 0.21 ENST00000264313.6
SLAIN motif family, member 2
chr4_+_38665810 0.20 ENST00000261438.5
ENST00000514033.1
Kruppel-like factor 3 (basic)
chr2_+_177028805 0.20 ENST00000249440.3
homeobox D3
chr19_-_47616992 0.19 ENST00000253048.5
zinc finger CCCH-type containing 4
chr15_-_25684110 0.18 ENST00000232165.3
ubiquitin protein ligase E3A
chr2_+_46769798 0.18 ENST00000238738.4
ras homolog family member Q
chr8_+_61591337 0.18 ENST00000423902.2
chromodomain helicase DNA binding protein 7
chr2_-_161350305 0.17 ENST00000348849.3
RNA binding motif, single stranded interacting protein 1
chr12_-_93835665 0.17 ENST00000552442.1
ENST00000550657.1
ubiquitin-conjugating enzyme E2N
chr12_+_58087901 0.17 ENST00000315970.7
ENST00000547079.1
ENST00000439210.2
ENST00000389146.6
ENST00000413095.2
ENST00000551035.1
ENST00000257966.8
ENST00000435406.2
ENST00000550372.1
ENST00000389142.5
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr5_-_133561752 0.17 ENST00000519718.1
ENST00000481195.1
S-phase kinase-associated protein 1
protein phosphatase 2, catalytic subunit, alpha isozyme
chr18_-_45456930 0.17 ENST00000262160.6
ENST00000587269.1
SMAD family member 2
chr8_+_17013515 0.16 ENST00000262096.8
zinc finger, DHHC-type containing 2
chr17_-_72889697 0.16 ENST00000310226.6
fatty acid desaturase 6
chr5_-_114598548 0.16 ENST00000379615.3
ENST00000419445.1
protein geranylgeranyltransferase type I, beta subunit
chr1_+_65730385 0.15 ENST00000263441.7
ENST00000395325.3
DnaJ (Hsp40) homolog, subfamily C, member 6
chr15_+_57210818 0.15 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
transcription factor 12
chr2_+_204192942 0.15 ENST00000295851.5
ENST00000261017.5
abl-interactor 2
chr2_+_137523086 0.15 ENST00000409968.1
thrombospondin, type I, domain containing 7B
chr13_+_58206655 0.15 ENST00000377918.3
protocadherin 17
chr8_+_124780672 0.14 ENST00000521166.1
ENST00000334705.7
family with sequence similarity 91, member A1
chr2_+_198380289 0.14 ENST00000233892.4
ENST00000409916.1
MOB family member 4, phocein
chr8_+_23104130 0.13 ENST00000313219.7
ENST00000519984.1
charged multivesicular body protein 7
chr3_+_30648066 0.13 ENST00000359013.4
transforming growth factor, beta receptor II (70/80kDa)
chr14_+_60715928 0.13 ENST00000395076.4
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr13_-_26795840 0.12 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
ring finger protein (C3H2C3 type) 6
chr1_+_181452678 0.12 ENST00000367570.1
ENST00000526775.1
ENST00000357570.5
ENST00000358338.5
ENST00000367567.4
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr9_-_14314066 0.12 ENST00000397575.3
nuclear factor I/B
chr3_+_19189946 0.12 ENST00000328405.2
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr4_+_79697495 0.11 ENST00000502871.1
ENST00000335016.5
BMP2 inducible kinase
chr14_-_91976488 0.11 ENST00000554684.1
ENST00000337238.4
ENST00000428424.2
ENST00000554511.1
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr8_-_99306611 0.10 ENST00000341166.3
NIPA-like domain containing 2
chr1_-_224033596 0.10 ENST00000391878.2
ENST00000343537.7
tumor protein p53 binding protein, 2
chr6_+_43211418 0.10 ENST00000259750.4
tau tubulin kinase 1
chr5_+_118407053 0.10 ENST00000311085.8
ENST00000539542.1
Dmx-like 1
chr3_-_33481835 0.09 ENST00000283629.3
upstream binding protein 1 (LBP-1a)
chr2_+_42275153 0.09 ENST00000294964.5
protein kinase domain containing, cytoplasmic
chr2_-_201936302 0.09 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
family with sequence similarity 126, member B
chr9_+_36036430 0.08 ENST00000377966.3
reversion-inducing-cysteine-rich protein with kazal motifs
chr6_-_109703663 0.08 ENST00000368961.5
CD164 molecule, sialomucin
chr7_+_139044621 0.08 ENST00000354926.4
C7orf55-LUC7L2 readthrough
chr14_-_93799360 0.08 ENST00000334746.5
ENST00000554565.1
ENST00000298896.3
BTB (POZ) domain containing 7
chr1_-_36863481 0.08 ENST00000315732.2
LSM10, U7 small nuclear RNA associated
chr19_-_47975417 0.08 ENST00000236877.6
solute carrier family 8 (sodium/calcium exchanger), member 2
chr17_-_40021656 0.08 ENST00000319121.3
kelch-like family member 11
chr1_+_20208870 0.08 ENST00000375120.3
OTU domain containing 3
chr3_-_116164306 0.07 ENST00000490035.2
limbic system-associated membrane protein
chr6_-_146135880 0.07 ENST00000237281.4
F-box protein 30
chr2_-_208634287 0.07 ENST00000295417.3
frizzled family receptor 5
chr2_+_30670077 0.07 ENST00000466477.1
ENST00000465200.1
ENST00000379509.3
ENST00000319406.4
ENST00000488144.1
ENST00000465538.1
ENST00000309052.4
ENST00000359433.1
lysocardiolipin acyltransferase 1
chr7_-_127032741 0.07 ENST00000393313.1
ENST00000265827.3
ENST00000434602.1
zinc finger protein 800
chr15_+_44829255 0.06 ENST00000261868.5
ENST00000424492.3
eukaryotic translation initiation factor 3, subunit J
chr15_-_51058005 0.06 ENST00000261854.5
signal peptide peptidase like 2A
chr4_+_174292058 0.05 ENST00000296504.3
Sin3A-associated protein, 30kDa
chr7_+_30067973 0.05 ENST00000258679.7
ENST00000449726.1
ENST00000396257.2
ENST00000396259.1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
chr1_-_37499726 0.04 ENST00000373091.3
ENST00000373093.4
glutamate receptor, ionotropic, kainate 3
chr7_-_143599207 0.03 ENST00000355951.2
ENST00000479870.1
ENST00000478172.1
family with sequence similarity 115, member A
chr14_+_102228123 0.03 ENST00000422945.2
ENST00000554442.1
ENST00000556260.2
ENST00000328724.5
ENST00000557268.1
protein phosphatase 2, regulatory subunit B', gamma
chr2_-_38604398 0.02 ENST00000443098.1
ENST00000449130.1
ENST00000378954.4
ENST00000539122.1
ENST00000419554.2
ENST00000451483.1
ENST00000406122.1
atlastin GTPase 2
chr4_-_100815525 0.02 ENST00000226522.8
ENST00000499666.2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr1_-_152332480 0.02 ENST00000388718.5
filaggrin family member 2
chr15_+_49715293 0.02 ENST00000267843.4
ENST00000560270.1
fibroblast growth factor 7
chr13_+_25946201 0.02 ENST00000381655.2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr2_-_70995307 0.01 ENST00000264436.4
ENST00000355733.3
ENST00000447731.2
ENST00000430656.1
ENST00000413157.2
adducin 2 (beta)
chr2_+_166326157 0.01 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
cysteine-serine-rich nuclear protein 3
chr15_+_85923856 0.01 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
A kinase (PRKA) anchor protein 13
chr4_-_6383594 0.01 ENST00000335585.5
protein phosphatase 2, regulatory subunit B, gamma
chr19_+_1286097 0.00 ENST00000215368.2
ephrin-A2

Network of associatons between targets according to the STRING database.

First level regulatory network of GAUUGUC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.0 5.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.8 2.4 GO:0048936 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913)
0.7 2.0 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.6 1.8 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.3 1.0 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.3 1.8 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.3 3.5 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.2 0.7 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 1.3 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 0.5 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 0.5 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.2 1.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.7 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.5 GO:0001555 oocyte growth(GO:0001555)
0.1 1.8 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.6 GO:0072719 cellular response to cisplatin(GO:0072719)
0.1 0.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.4 GO:0070253 somatostatin secretion(GO:0070253)
0.1 1.4 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.1 0.3 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.3 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.1 0.2 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 4.0 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 1.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.4 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 2.0 GO:0048148 behavioral response to cocaine(GO:0048148)
0.1 0.2 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.1 0.9 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.9 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 4.6 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.1 1.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.3 GO:0051946 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.9 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.0 1.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.6 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.8 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 1.0 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.3 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.6 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.6 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.0 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.5 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.3 GO:0009651 response to salt stress(GO:0009651)
0.0 0.3 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.2 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 1.8 GO:0007519 skeletal muscle tissue development(GO:0007519)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 0.9 GO:0019034 viral replication complex(GO:0019034)
0.1 1.4 GO:0036157 outer dynein arm(GO:0036157)
0.1 2.3 GO:0097440 apical dendrite(GO:0097440)
0.1 0.8 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.4 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 5.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 0.2 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.7 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 2.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 2.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 1.7 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.2 GO:0000502 proteasome complex(GO:0000502)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.4 1.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.3 1.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.3 0.8 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 0.9 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 1.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.9 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.7 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 1.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.7 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.9 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.6 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.8 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.4 GO:0004348 glucosylceramidase activity(GO:0004348) beta-glucosidase activity(GO:0008422)
0.1 2.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.5 GO:0042731 PH domain binding(GO:0042731)
0.1 0.5 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.2 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 6.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.7 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.0 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 1.3 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 3.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 4.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.9 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 2.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions