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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for GCM1

Z-value: 0.65

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Transcription factors associated with GCM1

Gene Symbol Gene ID Gene Info
GCM1
ENSG00000137270.10 glial cells missing transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GCM1hg19_v2_chr6_-_53013620_53013644-0.212.7e-01Click!

Activity profile of GCM1 motif

Sorted Z-values of GCM1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_57547454 1.34 ENST00000556376.2
HOPX
HOP homeobox
chr4_-_57547870 1.33 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX
HOP homeobox
chr2_+_90108504 1.25 ENST00000390271.2
IGKV6D-41
immunoglobulin kappa variable 6D-41 (non-functional)
chr11_+_13690249 1.05 ENST00000532701.1
FAR1
fatty acyl CoA reductase 1
chr2_+_90060377 1.04 ENST00000436451.2
IGKV6D-21
immunoglobulin kappa variable 6D-21 (non-functional)
chr2_-_89459813 0.98 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr20_-_1306351 0.98 ENST00000381812.1
SDCBP2
syndecan binding protein (syntenin) 2
chr20_+_361261 0.97 ENST00000217233.3
TRIB3
tribbles pseudokinase 3
chr20_-_1306391 0.95 ENST00000339987.3
SDCBP2
syndecan binding protein (syntenin) 2
chr12_-_122238464 0.88 ENST00000546227.1
RHOF
ras homolog family member F (in filopodia)
chr17_-_7493390 0.84 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15
SRY (sex determining region Y)-box 15
chr9_+_131182697 0.82 ENST00000372838.4
ENST00000411852.1
CERCAM
cerebral endothelial cell adhesion molecule
chr3_+_10206545 0.81 ENST00000256458.4
IRAK2
interleukin-1 receptor-associated kinase 2
chr14_+_24540046 0.72 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
CPNE6
copine VI (neuronal)
chr22_+_22936998 0.69 ENST00000390303.2
IGLV3-32
immunoglobulin lambda variable 3-32 (non-functional)
chr18_+_21529811 0.67 ENST00000588004.1
LAMA3
laminin, alpha 3
chr22_-_20256054 0.66 ENST00000043402.7
RTN4R
reticulon 4 receptor
chr11_+_111126707 0.65 ENST00000280325.4
C11orf53
chromosome 11 open reading frame 53
chr11_-_8190534 0.62 ENST00000309737.6
ENST00000425599.2
ENST00000539720.1
ENST00000531450.1
ENST00000419822.2
ENST00000335425.7
ENST00000343202.4
RIC3
RIC3 acetylcholine receptor chaperone
chr14_-_24732368 0.62 ENST00000544573.1
TGM1
transglutaminase 1
chr22_+_22786288 0.59 ENST00000390301.2
IGLV1-36
immunoglobulin lambda variable 1-36
chr11_+_844067 0.59 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
TSPAN4
tetraspanin 4
chr4_-_56502426 0.58 ENST00000505262.1
ENST00000507338.1
NMU
neuromedin U
chr18_+_21269556 0.50 ENST00000399516.3
LAMA3
laminin, alpha 3
chr17_-_14140166 0.48 ENST00000420162.2
ENST00000431716.2
CDRT15
CMT1A duplicated region transcript 15
chr22_-_20231207 0.48 ENST00000425986.1
RTN4R
reticulon 4 receptor
chr16_-_755726 0.47 ENST00000324361.5
FBXL16
F-box and leucine-rich repeat protein 16
chr22_-_20255212 0.46 ENST00000416372.1
RTN4R
reticulon 4 receptor
chr11_+_13690200 0.45 ENST00000354817.3
FAR1
fatty acyl CoA reductase 1
chr4_-_56502451 0.45 ENST00000511469.1
ENST00000264218.3
NMU
neuromedin U
chr19_-_48059113 0.44 ENST00000391901.3
ENST00000314121.4
ENST00000448976.1
ZNF541
zinc finger protein 541
chr12_-_69326940 0.43 ENST00000549781.1
ENST00000548262.1
ENST00000551568.1
ENST00000548954.1
CPM
carboxypeptidase M
chr22_+_44319648 0.42 ENST00000423180.2
PNPLA3
patatin-like phospholipase domain containing 3
chr18_+_21269404 0.42 ENST00000313654.9
LAMA3
laminin, alpha 3
chr14_+_24540731 0.41 ENST00000558859.1
ENST00000559197.1
ENST00000560828.1
ENST00000216775.2
ENST00000560884.1
CPNE6
copine VI (neuronal)
chr7_-_100253993 0.41 ENST00000461605.1
ENST00000160382.5
ACTL6B
actin-like 6B
chr17_+_40913264 0.40 ENST00000587142.1
ENST00000588576.1
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr9_+_4985016 0.39 ENST00000539801.1
JAK2
Janus kinase 2
chr10_-_43762329 0.39 ENST00000395810.1
RASGEF1A
RasGEF domain family, member 1A
chr10_+_15074190 0.37 ENST00000428897.1
ENST00000413672.1
OLAH
oleoyl-ACP hydrolase
chr16_-_755819 0.35 ENST00000397621.1
FBXL16
F-box and leucine-rich repeat protein 16
chr1_-_40237020 0.35 ENST00000327582.5
OXCT2
3-oxoacid CoA transferase 2
chr11_+_35198118 0.35 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44
CD44 molecule (Indian blood group)
chr18_-_5419797 0.35 ENST00000542146.1
ENST00000427684.2
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr11_+_124735282 0.34 ENST00000397801.1
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr4_-_8073705 0.34 ENST00000514025.1
ABLIM2
actin binding LIM protein family, member 2
chr17_+_80517216 0.33 ENST00000531030.1
ENST00000526383.2
FOXK2
forkhead box K2
chr16_-_74734672 0.32 ENST00000306247.7
ENST00000575686.1
MLKL
mixed lineage kinase domain-like
chr2_+_47168630 0.32 ENST00000263737.6
TTC7A
tetratricopeptide repeat domain 7A
chr3_+_12329397 0.32 ENST00000397015.2
PPARG
peroxisome proliferator-activated receptor gamma
chr19_-_3480540 0.32 ENST00000215531.4
C19orf77
chromosome 19 open reading frame 77
chr10_-_73975657 0.31 ENST00000394919.1
ENST00000526751.1
ASCC1
activating signal cointegrator 1 complex subunit 1
chr4_-_987217 0.31 ENST00000361661.2
ENST00000398516.2
SLC26A1
solute carrier family 26 (anion exchanger), member 1
chr3_+_12329358 0.31 ENST00000309576.6
PPARG
peroxisome proliferator-activated receptor gamma
chr19_-_52227221 0.30 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chr1_+_25071848 0.30 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr6_+_30029008 0.29 ENST00000332435.5
ENST00000376782.2
ENST00000359374.4
ENST00000376785.2
ZNRD1
zinc ribbon domain containing 1
chr10_-_73976025 0.29 ENST00000342444.4
ENST00000533958.1
ENST00000527593.1
ENST00000394915.3
ENST00000530461.1
ENST00000317168.6
ENST00000524829.1
ASCC1
activating signal cointegrator 1 complex subunit 1
chr4_-_40859132 0.28 ENST00000543538.1
ENST00000502841.1
ENST00000504305.1
ENST00000513516.1
ENST00000510670.1
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr16_-_74734742 0.28 ENST00000308807.7
ENST00000573267.1
MLKL
mixed lineage kinase domain-like
chr12_+_8666126 0.28 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr19_+_12902289 0.28 ENST00000302754.4
JUNB
jun B proto-oncogene
chr18_+_10526008 0.28 ENST00000542979.1
ENST00000322897.6
NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr10_-_105677427 0.27 ENST00000369764.1
OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
chr8_-_144099795 0.27 ENST00000522060.1
ENST00000517833.1
ENST00000502167.2
ENST00000518831.1
RP11-273G15.2
RP11-273G15.2
chr7_-_100860851 0.26 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr16_-_90096309 0.25 ENST00000408886.2
C16orf3
chromosome 16 open reading frame 3
chr11_-_62783276 0.25 ENST00000535878.1
ENST00000545207.1
SLC22A8
solute carrier family 22 (organic anion transporter), member 8
chr5_+_135385202 0.25 ENST00000514554.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr4_-_52904425 0.25 ENST00000535450.1
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr16_-_19729502 0.24 ENST00000219837.7
KNOP1
lysine-rich nucleolar protein 1
chr9_+_17579084 0.24 ENST00000380607.4
SH3GL2
SH3-domain GRB2-like 2
chr9_-_111619239 0.24 ENST00000374667.3
ACTL7B
actin-like 7B
chr1_+_44399466 0.24 ENST00000498139.2
ENST00000491846.1
ARTN
artemin
chr6_+_33589161 0.24 ENST00000605930.1
ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
chr2_-_89630186 0.24 ENST00000390264.2
IGKV2-40
immunoglobulin kappa variable 2-40
chr16_-_57513657 0.23 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
DOK4
docking protein 4
chr19_+_11546440 0.23 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH
protein kinase C substrate 80K-H
chr22_+_38864041 0.23 ENST00000216014.4
ENST00000409006.3
KDELR3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr12_-_122238913 0.22 ENST00000537157.1
AC084018.1
AC084018.1
chr17_+_40913210 0.22 ENST00000253796.5
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chrX_-_152486108 0.22 ENST00000356661.5
MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr14_-_50778872 0.22 ENST00000555610.1
ENST00000261699.4
L2HGDH
L-2-hydroxyglutarate dehydrogenase
chr19_-_6379069 0.22 ENST00000597721.1
PSPN
persephin
chr20_+_33563206 0.21 ENST00000262873.7
MYH7B
myosin, heavy chain 7B, cardiac muscle, beta
chr19_-_38397228 0.21 ENST00000447313.2
WDR87
WD repeat domain 87
chr7_-_26904317 0.20 ENST00000345317.2
SKAP2
src kinase associated phosphoprotein 2
chr3_-_196242233 0.20 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr3_-_121468513 0.20 ENST00000494517.1
ENST00000393667.3
GOLGB1
golgin B1
chr20_-_45061695 0.20 ENST00000445496.2
ELMO2
engulfment and cell motility 2
chr3_-_121468602 0.20 ENST00000340645.5
GOLGB1
golgin B1
chr8_+_25316707 0.20 ENST00000380665.3
CDCA2
cell division cycle associated 2
chr5_-_133702761 0.20 ENST00000521118.1
ENST00000265334.4
ENST00000435211.1
CDKL3
cyclin-dependent kinase-like 3
chr8_+_142138799 0.20 ENST00000518668.1
DENND3
DENN/MADD domain containing 3
chr16_+_56598961 0.20 ENST00000219162.3
MT4
metallothionein 4
chr2_+_233320827 0.20 ENST00000295463.3
ALPI
alkaline phosphatase, intestinal
chr7_-_44179972 0.20 ENST00000446581.1
MYL7
myosin, light chain 7, regulatory
chr16_-_85722530 0.19 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr1_-_11907829 0.19 ENST00000376480.3
NPPA
natriuretic peptide A
chr17_-_40913275 0.19 ENST00000589716.1
ENST00000360166.3
RAMP2-AS1
RAMP2 antisense RNA 1
chr19_-_38397285 0.18 ENST00000303868.5
WDR87
WD repeat domain 87
chrX_-_27417088 0.18 ENST00000608735.1
ENST00000422048.1
RP11-268G12.1
RP11-268G12.1
chr8_+_104383728 0.18 ENST00000330295.5
CTHRC1
collagen triple helix repeat containing 1
chr15_+_78632666 0.18 ENST00000299529.6
CRABP1
cellular retinoic acid binding protein 1
chr19_+_11658655 0.17 ENST00000588935.1
CNN1
calponin 1, basic, smooth muscle
chr11_+_31531291 0.17 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr3_+_130613226 0.17 ENST00000509662.1
ENST00000328560.8
ENST00000428331.2
ENST00000359644.3
ENST00000422190.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr4_+_110749143 0.17 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr2_+_88469835 0.17 ENST00000358591.2
ENST00000377254.3
ENST00000402102.1
ENST00000419759.1
ENST00000449349.1
ENST00000343544.4
THNSL2
threonine synthase-like 2 (S. cerevisiae)
chr6_-_30043539 0.17 ENST00000376751.3
ENST00000244360.6
RNF39
ring finger protein 39
chr17_-_39140549 0.17 ENST00000377755.4
KRT40
keratin 40
chr10_+_96162242 0.17 ENST00000225235.4
TBC1D12
TBC1 domain family, member 12
chr9_-_115653176 0.17 ENST00000374228.4
SLC46A2
solute carrier family 46, member 2
chr2_+_208527094 0.16 ENST00000429730.1
AC079767.4
AC079767.4
chr13_-_78492927 0.16 ENST00000334286.5
EDNRB
endothelin receptor type B
chr10_-_105677886 0.16 ENST00000224950.3
OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
chr3_-_128369643 0.16 ENST00000296255.3
RPN1
ribophorin I
chr19_+_641178 0.16 ENST00000166133.3
FGF22
fibroblast growth factor 22
chr20_+_30225682 0.16 ENST00000376075.3
COX4I2
cytochrome c oxidase subunit IV isoform 2 (lung)
chr16_+_2285817 0.16 ENST00000564065.1
DNASE1L2
deoxyribonuclease I-like 2
chr6_-_74363803 0.16 ENST00000355773.5
SLC17A5
solute carrier family 17 (acidic sugar transporter), member 5
chr2_-_106810742 0.16 ENST00000409501.3
ENST00000428048.2
ENST00000441952.1
ENST00000457835.1
ENST00000540130.1
UXS1
UDP-glucuronate decarboxylase 1
chr17_-_4269920 0.16 ENST00000572484.1
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr16_+_2022036 0.15 ENST00000568546.1
TBL3
transducin (beta)-like 3
chr8_-_57232656 0.15 ENST00000396721.2
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr2_-_106810783 0.15 ENST00000283148.7
UXS1
UDP-glucuronate decarboxylase 1
chr19_+_54705025 0.14 ENST00000441429.1
RPS9
ribosomal protein S9
chr20_+_44441304 0.14 ENST00000352551.5
UBE2C
ubiquitin-conjugating enzyme E2C
chr15_-_94443820 0.14 ENST00000557481.2
CTD-3049M7.1
CTD-3049M7.1
chr7_-_150780609 0.14 ENST00000297533.4
TMUB1
transmembrane and ubiquitin-like domain containing 1
chr12_-_39300071 0.14 ENST00000550863.1
CPNE8
copine VIII
chr6_-_136847610 0.14 ENST00000454590.1
ENST00000432797.2
MAP7
microtubule-associated protein 7
chrX_-_84634737 0.14 ENST00000262753.4
POF1B
premature ovarian failure, 1B
chr1_-_2145620 0.14 ENST00000545087.1
AL590822.1
Uncharacterized protein
chr1_+_11796126 0.14 ENST00000376637.3
AGTRAP
angiotensin II receptor-associated protein
chr2_-_24583168 0.14 ENST00000361999.3
ITSN2
intersectin 2
chr15_-_45422056 0.14 ENST00000267803.4
ENST00000559014.1
ENST00000558851.1
ENST00000559988.1
ENST00000558996.1
ENST00000558422.1
ENST00000559226.1
ENST00000558326.1
ENST00000558377.1
ENST00000559644.1
DUOXA1
dual oxidase maturation factor 1
chr1_+_24069642 0.13 ENST00000418390.2
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr1_+_24069952 0.13 ENST00000609199.1
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr16_+_67062996 0.13 ENST00000561924.2
CBFB
core-binding factor, beta subunit
chr17_-_62340581 0.13 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
TEX2
testis expressed 2
chr19_-_7797045 0.13 ENST00000328853.5
CLEC4G
C-type lectin domain family 4, member G
chrX_-_84634708 0.13 ENST00000373145.3
POF1B
premature ovarian failure, 1B
chr1_-_26394114 0.13 ENST00000374272.3
TRIM63
tripartite motif containing 63, E3 ubiquitin protein ligase
chr5_+_140767452 0.13 ENST00000519479.1
PCDHGB4
protocadherin gamma subfamily B, 4
chr5_-_127674883 0.12 ENST00000507835.1
FBN2
fibrillin 2
chr2_-_89385283 0.12 ENST00000390252.2
IGKV3-15
immunoglobulin kappa variable 3-15
chr7_-_4901625 0.12 ENST00000404991.1
PAPOLB
poly(A) polymerase beta (testis specific)
chr9_+_138628365 0.12 ENST00000491806.2
ENST00000488444.2
ENST00000490355.2
ENST00000263604.3
KCNT1
potassium channel, subfamily T, member 1
chr19_-_1650666 0.11 ENST00000588136.1
TCF3
transcription factor 3
chr11_+_64058758 0.11 ENST00000538767.1
KCNK4
potassium channel, subfamily K, member 4
chr6_+_3068606 0.11 ENST00000259808.4
RIPK1
receptor (TNFRSF)-interacting serine-threonine kinase 1
chr18_-_18691739 0.11 ENST00000399799.2
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chr22_+_22930626 0.11 ENST00000390302.2
IGLV2-33
immunoglobulin lambda variable 2-33 (non-functional)
chr12_-_4554780 0.11 ENST00000228837.2
FGF6
fibroblast growth factor 6
chr4_+_56212505 0.10 ENST00000505210.1
SRD5A3
steroid 5 alpha-reductase 3
chr2_-_113993020 0.10 ENST00000465084.1
PAX8
paired box 8
chr16_+_67063262 0.10 ENST00000565389.1
CBFB
core-binding factor, beta subunit
chr7_+_99971068 0.10 ENST00000198536.2
ENST00000453419.1
PILRA
paired immunoglobin-like type 2 receptor alpha
chr4_-_48782259 0.10 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRYL
FRY-like
chr19_+_35842445 0.10 ENST00000246553.2
FFAR1
free fatty acid receptor 1
chr20_+_36946029 0.10 ENST00000417318.1
BPI
bactericidal/permeability-increasing protein
chr14_-_54908043 0.10 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr1_+_11796177 0.10 ENST00000400895.2
ENST00000376629.4
ENST00000376627.2
ENST00000314340.5
ENST00000452018.2
ENST00000510878.1
AGTRAP
angiotensin II receptor-associated protein
chr17_-_4269768 0.09 ENST00000396981.2
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr9_-_99540328 0.09 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
ZNF510
zinc finger protein 510
chr4_+_56212270 0.09 ENST00000264228.4
SRD5A3
steroid 5 alpha-reductase 3
chr19_+_54704718 0.09 ENST00000391752.1
ENST00000402367.1
ENST00000391751.3
RPS9
ribosomal protein S9
chr17_-_3599492 0.09 ENST00000435558.1
ENST00000345901.3
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr4_-_119274121 0.09 ENST00000296498.3
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr15_-_78933567 0.09 ENST00000261751.3
ENST00000412074.2
CHRNB4
cholinergic receptor, nicotinic, beta 4 (neuronal)
chr11_+_20385231 0.09 ENST00000530266.1
ENST00000421577.2
ENST00000443524.2
ENST00000419348.2
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr11_+_64058820 0.09 ENST00000422670.2
KCNK4
potassium channel, subfamily K, member 4
chr11_+_20385666 0.09 ENST00000532081.1
ENST00000531058.1
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr2_+_234959323 0.08 ENST00000373368.1
ENST00000168148.3
SPP2
secreted phosphoprotein 2, 24kDa
chr17_-_3599327 0.08 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr22_+_22599189 0.08 ENST00000302273.2
VPREB1
pre-B lymphocyte 1
chr21_-_38445443 0.08 ENST00000360525.4
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr9_-_138591341 0.08 ENST00000298466.5
ENST00000425225.1
SOHLH1
spermatogenesis and oogenesis specific basic helix-loop-helix 1
chr4_+_38511367 0.08 ENST00000507056.1
RP11-213G21.1
RP11-213G21.1
chr19_-_1021113 0.08 ENST00000333175.5
ENST00000356663.3
TMEM259
transmembrane protein 259
chr19_+_50936142 0.08 ENST00000357701.5
MYBPC2
myosin binding protein C, fast type
chr7_-_50132860 0.08 ENST00000046087.2
ZPBP
zona pellucida binding protein
chr22_+_22764088 0.08 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr7_-_50132801 0.08 ENST00000419417.1
ZPBP
zona pellucida binding protein
chr19_+_54704990 0.08 ENST00000391753.2
RPS9
ribosomal protein S9
chr1_-_1690014 0.08 ENST00000400922.2
ENST00000342348.5
NADK
NAD kinase
chr20_+_34043085 0.08 ENST00000397527.1
ENST00000342580.4
CEP250
centrosomal protein 250kDa
chr6_-_132032206 0.08 ENST00000314099.8
CTAGE9
CTAGE family, member 9
chr3_+_46448648 0.08 ENST00000399036.3
CCRL2
chemokine (C-C motif) receptor-like 2
chr3_+_130613001 0.07 ENST00000504948.1
ENST00000513801.1
ENST00000505072.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr20_+_30639991 0.07 ENST00000534862.1
ENST00000538448.1
ENST00000375862.2
HCK
hemopoietic cell kinase
chr7_+_100860949 0.07 ENST00000305105.2
ZNHIT1
zinc finger, HIT-type containing 1
chr8_-_97247759 0.07 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
UQCRB
ubiquinol-cytochrome c reductase binding protein
chr4_-_17783135 0.07 ENST00000265018.3
FAM184B
family with sequence similarity 184, member B
chr1_-_8938736 0.07 ENST00000234590.4
ENO1
enolase 1, (alpha)
chr1_-_159880159 0.07 ENST00000599780.1
AL590560.1
HCG1995379; Uncharacterized protein
chr7_+_143880559 0.07 ENST00000486333.1
CTAGE4
CTAGE family, member 4
chr14_+_39736299 0.07 ENST00000341502.5
ENST00000396158.2
ENST00000280083.3
CTAGE5
CTAGE family, member 5
chr22_+_19705928 0.07 ENST00000383045.3
ENST00000438754.2
SEPT5
septin 5

Network of associatons between targets according to the STRING database.

First level regulatory network of GCM1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.3 0.8 GO:0048627 myoblast development(GO:0048627)
0.2 0.6 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.2 0.6 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 3.0 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 1.0 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.1 0.3 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 1.6 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.3 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.4 GO:1902728 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.6 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.2 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.1 0.2 GO:0006566 threonine metabolic process(GO:0006566)
0.1 1.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.1 GO:0007497 posterior midgut development(GO:0007497)
0.0 0.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.2 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.2 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0003335 corneocyte development(GO:0003335)
0.0 1.0 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.3 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.2 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.3 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.0 0.4 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 1.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.8 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.3 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 4.6 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:2001171 positive regulation of ATP biosynthetic process(GO:2001171)
0.0 0.1 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.6 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.0 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.2 GO:0097484 dendrite extension(GO:0097484)
0.0 0.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.3 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.6 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 1.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 1.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.4 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 1.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0038131 neuregulin receptor activity(GO:0038131)
0.3 1.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.4 GO:0016296 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.1 0.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.6 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.2 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.3 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.2 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 1.0 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 1.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.3 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 1.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.0 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.0 GO:0070546 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 3.0 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling