Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for GFI1

Z-value: 1.08

Motif logo

Transcription factors associated with GFI1

Gene Symbol Gene ID Gene Info
ENSG00000162676.7 growth factor independent 1 transcriptional repressor

Activity-expression correlation:

Activity profile of GFI1 motif

Sorted Z-values of GFI1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_94727048 7.33 ENST00000283357.5
family with sequence similarity 81, member B
chr1_-_60539422 6.81 ENST00000371201.3
chromosome 1 open reading frame 87
chr1_-_60539405 6.59 ENST00000450089.2
chromosome 1 open reading frame 87
chr17_+_45908974 5.98 ENST00000269025.4
leucine rich repeat containing 46
chr19_-_9092018 5.94 ENST00000397910.4
mucin 16, cell surface associated
chr1_-_109655355 5.91 ENST00000369945.3
chromosome 1 open reading frame 194
chr1_-_109655377 5.84 ENST00000369948.3
chromosome 1 open reading frame 194
chr9_-_117150243 3.85 ENST00000374088.3
AT-hook transcription factor
chr6_-_32920794 3.69 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr11_+_71900703 3.30 ENST00000393681.2
folate receptor 1 (adult)
chrX_+_53449887 3.30 ENST00000375327.3
RIB43A domain with coiled-coils 1
chr5_-_61031495 3.27 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
chr17_-_19281203 3.25 ENST00000487415.2
B9 protein domain 1
chr11_+_71791849 2.93 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
leucine rich transmembrane and O-methyltransferase domain containing
chr11_+_71900572 2.90 ENST00000312293.4
folate receptor 1 (adult)
chr16_-_53737795 2.89 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1-like
chr6_+_159084188 2.89 ENST00000367081.3
synaptotagmin-like 3
chr16_-_53737722 2.86 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1-like
chr15_-_56757329 2.85 ENST00000260453.3
meiosis-specific nuclear structural 1
chr3_-_190580404 2.84 ENST00000442080.1
geminin coiled-coil domain containing
chr3_-_45957088 2.80 ENST00000539217.1
leucine zipper transcription factor-like 1
chr11_+_71791359 2.79 ENST00000419228.1
ENST00000435085.1
ENST00000307198.7
ENST00000538413.1
leucine rich transmembrane and O-methyltransferase domain containing
chr1_+_162351503 2.65 ENST00000458626.2
chromosome 1 open reading frame 226
chr11_+_71791693 2.55 ENST00000289488.2
ENST00000447974.1
leucine rich transmembrane and O-methyltransferase domain containing
chr17_+_26800756 2.51 ENST00000537681.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr3_-_45957534 2.50 ENST00000536047.1
leucine zipper transcription factor-like 1
chr17_+_26800648 2.47 ENST00000545060.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chrX_+_53449805 2.42 ENST00000414955.2
RIB43A domain with coiled-coils 1
chr5_+_36608422 2.37 ENST00000381918.3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_+_68071389 2.35 ENST00000283936.1
ENST00000392671.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr17_+_26800296 2.32 ENST00000444914.3
ENST00000314669.5
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr17_+_68071458 2.31 ENST00000589377.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr11_+_71791803 2.30 ENST00000539271.1
leucine rich transmembrane and O-methyltransferase domain containing
chr5_-_110062384 2.27 ENST00000429839.2
transmembrane protein 232
chr5_-_110062349 2.24 ENST00000511883.2
ENST00000455884.2
transmembrane protein 232
chr6_+_6588902 2.20 ENST00000230568.4
lymphocyte antigen 86
chr19_+_16059818 2.18 ENST00000322107.1
olfactory receptor, family 10, subfamily H, member 4
chr16_+_82090028 2.18 ENST00000568090.1
hydroxysteroid (17-beta) dehydrogenase 2
chr7_+_90339169 2.17 ENST00000436577.2
cyclin-dependent kinase 14
chr15_-_52587945 2.14 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
myosin VC
chr1_+_61542922 1.99 ENST00000407417.3
nuclear factor I/A
chr5_-_35230434 1.94 ENST00000504500.1
prolactin receptor
chr10_-_13523073 1.81 ENST00000440282.1
BEN domain containing 7
chr4_+_41614909 1.77 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr21_-_36421626 1.76 ENST00000300305.3
runt-related transcription factor 1
chr14_-_23285069 1.75 ENST00000554758.1
ENST00000397528.4
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_+_7761013 1.75 ENST00000571846.1
cytochrome b5 domain containing 1
chr3_-_66024213 1.74 ENST00000483466.1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr3_+_125694347 1.74 ENST00000505382.1
ENST00000511082.1
rhophilin associated tail protein 1B
chr14_-_23285011 1.71 ENST00000397532.3
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr21_-_36421535 1.70 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
runt-related transcription factor 1
chr19_+_36236514 1.70 ENST00000222266.2
presenilin enhancer gamma secretase subunit
chr19_+_36236491 1.68 ENST00000591949.1
presenilin enhancer gamma secretase subunit
chr7_+_120591170 1.64 ENST00000431467.1
inhibitor of growth family, member 3
chr5_+_140261703 1.59 ENST00000409494.1
ENST00000289272.2
protocadherin alpha 13
chr12_+_113587558 1.55 ENST00000335621.6
coiled-coil domain containing 42B
chr3_-_114477962 1.55 ENST00000471418.1
zinc finger and BTB domain containing 20
chr17_-_63557759 1.55 ENST00000307078.5
axin 2
chr7_+_114055052 1.50 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
forkhead box P2
chr12_-_113658892 1.50 ENST00000299732.2
ENST00000416617.2
IQ motif containing D
chr11_+_36397528 1.49 ENST00000311599.5
ENST00000378867.3
proline rich 5 like
chr3_-_114477787 1.47 ENST00000464560.1
zinc finger and BTB domain containing 20
chr2_-_238499725 1.46 ENST00000264601.3
RAB17, member RAS oncogene family
chr1_-_49242553 1.45 ENST00000371833.3
BEN domain containing 5
chr4_+_41362796 1.44 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIM and calponin homology domains 1
chr7_+_90338712 1.44 ENST00000265741.3
ENST00000406263.1
cyclin-dependent kinase 14
chr11_+_1889880 1.42 ENST00000405957.2
lymphocyte-specific protein 1
chr9_-_79520989 1.42 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
prune homolog 2 (Drosophila)
chr16_-_18441131 1.40 ENST00000339303.5
nuclear pore complex interacting protein family, member A8
chr2_+_183943464 1.39 ENST00000354221.4
dual specificity phosphatase 19
chr2_+_98330009 1.36 ENST00000264972.5
zeta-chain (TCR) associated protein kinase 70kDa
chr15_+_84116106 1.32 ENST00000535412.1
ENST00000324537.5
SH3-domain GRB2-like 3
chr3_-_114343039 1.32 ENST00000481632.1
zinc finger and BTB domain containing 20
chr1_+_156338993 1.31 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
Rh family, B glycoprotein (gene/pseudogene)
chr11_+_111789580 1.31 ENST00000278601.5
chromosome 11 open reading frame 52
chr19_+_41281416 1.26 ENST00000597140.1
melanoma inhibitory activity
chr14_+_22771851 1.23 ENST00000390466.1
T cell receptor alpha variable 39
chr7_-_120498357 1.23 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr15_+_84115868 1.21 ENST00000427482.2
SH3-domain GRB2-like 3
chr6_-_32908792 1.20 ENST00000418107.2
major histocompatibility complex, class II, DM beta
chr16_+_4838412 1.19 ENST00000589327.1
small integral membrane protein 22
chr11_-_4629388 1.17 ENST00000526337.1
ENST00000300747.5
tripartite motif containing 68
chr6_-_111804393 1.14 ENST00000368802.3
ENST00000368805.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr19_+_41281060 1.14 ENST00000594436.1
ENST00000597784.1
melanoma inhibitory activity
chr12_-_15104040 1.14 ENST00000541644.1
ENST00000545895.1
Rho GDP dissociation inhibitor (GDI) beta
chr9_+_2158485 1.12 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr19_+_47813110 1.12 ENST00000355085.3
complement component 5a receptor 1
chr3_-_158450231 1.11 ENST00000479756.1
retinoic acid receptor responder (tazarotene induced) 1
chr15_-_49255632 1.11 ENST00000332408.4
SHC (Src homology 2 domain containing) family, member 4
chr19_+_6772710 1.10 ENST00000304076.2
ENST00000602142.1
ENST00000596764.1
vav 1 guanine nucleotide exchange factor
chr3_+_108321623 1.09 ENST00000497905.1
ENST00000463306.1
DAZ interacting zinc finger protein 3
chr15_+_96875657 1.09 ENST00000559679.1
ENST00000394171.2
nuclear receptor subfamily 2, group F, member 2
chr19_+_41281282 1.08 ENST00000263369.3
melanoma inhibitory activity
chr8_-_133772794 1.07 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
transmembrane protein 71
chr1_-_10856694 1.07 ENST00000377022.3
ENST00000344008.5
castor zinc finger 1
chr9_+_2158443 1.07 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_111291587 1.07 ENST00000437167.1
RANBP2-like and GRIP domain containing 6
chr17_+_3539744 1.07 ENST00000046640.3
ENST00000381870.3
cystinosin, lysosomal cystine transporter
chr18_+_55711575 1.07 ENST00000356462.6
ENST00000400345.3
ENST00000589054.1
ENST00000256832.7
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr6_-_36842784 1.05 ENST00000373699.5
peptidylprolyl isomerase (cyclophilin)-like 1
chr11_-_8954491 1.04 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
chromosome 11 open reading frame 16
chr16_+_19183671 1.00 ENST00000562711.2
synaptotagmin XVII
chr11_+_61717336 1.00 ENST00000378042.3
bestrophin 1
chr2_-_152830479 0.98 ENST00000360283.6
calcium channel, voltage-dependent, beta 4 subunit
chr4_+_89299885 0.96 ENST00000380265.5
ENST00000273960.3
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr4_+_89299994 0.95 ENST00000264346.7
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr4_+_41614720 0.93 ENST00000509277.1
LIM and calponin homology domains 1
chr5_+_133451254 0.91 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
transcription factor 7 (T-cell specific, HMG-box)
chr14_-_20774092 0.91 ENST00000423949.2
ENST00000553828.1
ENST00000258821.3
tetratricopeptide repeat domain 5
chr11_+_61717279 0.91 ENST00000378043.4
bestrophin 1
chr9_+_976964 0.91 ENST00000190165.2
doublesex and mab-3 related transcription factor 3
chr1_-_48866517 0.90 ENST00000371841.1
spermatogenesis associated 6
chr16_-_18470696 0.90 ENST00000427999.2
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chrX_+_48681768 0.90 ENST00000430858.1
histone deacetylase 6
chr3_-_158450475 0.89 ENST00000237696.5
retinoic acid receptor responder (tazarotene induced) 1
chr8_+_40010989 0.88 ENST00000315792.3
chromosome 8 open reading frame 4
chr17_-_39280419 0.88 ENST00000394014.1
keratin associated protein 4-12
chr9_-_69202204 0.87 ENST00000377473.1
forkhead box D4-like 6
chr9_+_70917276 0.84 ENST00000342833.2
forkhead box D4-like 3
chr7_+_120590803 0.84 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
inhibitor of growth family, member 3
chr9_+_2159850 0.84 ENST00000416751.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_+_100612904 0.83 ENST00000379442.3
ENST00000536621.1
mucin 12, cell surface associated
chr17_+_76311791 0.83 ENST00000586321.1
AC061992.2
chr6_+_45296391 0.82 ENST00000371436.6
ENST00000576263.1
runt-related transcription factor 2
chr1_+_164528866 0.81 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr17_-_63557309 0.81 ENST00000580513.1
axin 2
chr5_-_74807418 0.80 ENST00000405807.4
ENST00000261415.7
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr11_-_94964354 0.79 ENST00000536441.1
sestrin 3
chr9_-_70178815 0.78 ENST00000377420.1
forkhead box D4-like 5
chr9_+_42717234 0.78 ENST00000377590.1
forkhead box D4-like 2
chrX_-_108725301 0.78 ENST00000218006.2
guanylate cyclase 2F, retinal
chr10_-_120355149 0.77 ENST00000239032.2
prolactin releasing hormone receptor
chr1_+_210406121 0.77 ENST00000367012.3
SERTA domain containing 4
chr17_-_56606639 0.76 ENST00000579371.1
septin 4
chr9_-_112260531 0.76 ENST00000374541.2
ENST00000262539.3
protein tyrosine phosphatase, non-receptor type 3
chr12_-_42877408 0.75 ENST00000552240.1
prickle homolog 1 (Drosophila)
chr22_+_31518938 0.75 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
inositol polyphosphate-5-phosphatase J
chr17_-_56606705 0.75 ENST00000317268.3
septin 4
chr6_+_31795506 0.75 ENST00000375650.3
heat shock 70kDa protein 1B
chr17_-_56606664 0.75 ENST00000580844.1
septin 4
chrX_+_12885183 0.75 ENST00000380659.3
toll-like receptor 7
chr11_+_61717535 0.74 ENST00000534553.1
ENST00000301774.9
bestrophin 1
chr2_-_152830441 0.72 ENST00000534999.1
ENST00000397327.2
calcium channel, voltage-dependent, beta 4 subunit
chr1_-_67142710 0.72 ENST00000502413.2
Uncharacterized protein
chr19_+_54496132 0.71 ENST00000346968.2
calcium channel, voltage-dependent, gamma subunit 6
chr16_+_4838393 0.71 ENST00000589721.1
small integral membrane protein 22
chr6_-_49712147 0.70 ENST00000433368.2
ENST00000354620.4
cysteine-rich secretory protein 3
chr5_-_111091948 0.69 ENST00000447165.2
neuronal regeneration related protein
chr6_-_55739542 0.69 ENST00000446683.2
bone morphogenetic protein 5
chr19_-_10687907 0.69 ENST00000589348.1
adaptor-related protein complex 1, mu 2 subunit
chr4_-_681114 0.69 ENST00000503156.1
major facilitator superfamily domain containing 7
chr5_-_19988339 0.69 ENST00000382275.1
cadherin 18, type 2
chr14_-_106069247 0.69 ENST00000479229.1
RP11-731F5.1
chr6_+_26440700 0.68 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr19_-_46088068 0.67 ENST00000263275.4
ENST00000323060.3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr2_-_96874553 0.67 ENST00000337288.5
ENST00000443962.1
StAR-related lipid transfer (START) domain containing 7
chr6_-_49712123 0.67 ENST00000263045.4
cysteine-rich secretory protein 3
chrX_+_106871713 0.66 ENST00000372435.4
ENST00000372428.4
ENST00000372419.3
ENST00000543248.1
phosphoribosyl pyrophosphate synthetase 1
chr5_-_59783882 0.66 ENST00000505507.2
ENST00000502484.2
phosphodiesterase 4D, cAMP-specific
chr2_-_69180012 0.66 ENST00000481498.1
gastrokine 2
chr12_-_42877726 0.66 ENST00000548696.1
prickle homolog 1 (Drosophila)
chr18_-_30050395 0.66 ENST00000269209.6
ENST00000399218.4
GRB2 associated, regulator of MAPK1
chr3_-_161090660 0.65 ENST00000359175.4
serine palmitoyltransferase, small subunit B
chr9_+_123837141 0.65 ENST00000373865.2
centriolin
chr21_-_43430440 0.64 ENST00000398505.3
ENST00000310826.5
ENST00000449949.1
ENST00000398499.1
ENST00000398497.2
ENST00000398511.3
zinc finger and BTB domain containing 21
chr16_+_24266874 0.64 ENST00000005284.3
calcium channel, voltage-dependent, gamma subunit 3
chr6_+_136172820 0.64 ENST00000308191.6
phosphodiesterase 7B
chr2_+_47630108 0.63 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
mutS homolog 2
chr12_+_50017327 0.63 ENST00000261897.1
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr11_+_61129456 0.62 ENST00000278826.6
transmembrane protein 138
chr8_-_57232656 0.62 ENST00000396721.2
short chain dehydrogenase/reductase family 16C, member 5
chr2_+_27799389 0.61 ENST00000408964.2
chromosome 2 open reading frame 16
chr6_+_29364416 0.61 ENST00000383555.2
olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
chr12_-_42877764 0.61 ENST00000455697.1
prickle homolog 1 (Drosophila)
chr19_-_49140692 0.60 ENST00000222122.5
D site of albumin promoter (albumin D-box) binding protein
chr3_-_11623804 0.60 ENST00000451674.2
vestigial like 4 (Drosophila)
chr4_+_76995855 0.60 ENST00000355810.4
ENST00000349321.3
ADP-ribosyltransferase 3
chr1_-_157014865 0.60 ENST00000361409.2
Rho guanine nucleotide exchange factor (GEF) 11
chr17_+_1665345 0.60 ENST00000576406.1
ENST00000571149.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr18_-_53257027 0.60 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
transcription factor 4
chr15_-_42500351 0.59 ENST00000348544.4
ENST00000318006.5
vacuolar protein sorting 39 homolog (S. cerevisiae)
chr8_-_145642267 0.58 ENST00000301305.3
solute carrier family 39 (zinc transporter), member 4
chr1_+_153940713 0.57 ENST00000368601.1
ENST00000368603.1
ENST00000368600.3
cAMP responsive element binding protein 3-like 4
chr19_+_50353944 0.57 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
prostate tumor overexpressed 1
chr10_-_65028817 0.56 ENST00000542921.1
jumonji domain containing 1C
chr11_+_123986069 0.56 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
von Willebrand factor A domain containing 5A
chr19_+_54495542 0.56 ENST00000252729.2
ENST00000352529.1
calcium channel, voltage-dependent, gamma subunit 6
chr6_-_161695042 0.55 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
1-acylglycerol-3-phosphate O-acyltransferase 4
chr12_+_71833550 0.55 ENST00000266674.5
leucine-rich repeat containing G protein-coupled receptor 5
chrX_-_53449593 0.55 ENST00000375340.6
ENST00000322213.4
structural maintenance of chromosomes 1A
chr19_+_55477711 0.55 ENST00000448584.2
ENST00000537859.1
ENST00000585500.1
ENST00000427260.2
ENST00000538819.1
ENST00000263437.6
NLR family, pyrin domain containing 2
chr7_-_92848878 0.55 ENST00000341723.4
HEPACAM family member 2
chr12_+_57998400 0.55 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
deltex homolog 3 (Drosophila)
chr4_-_144940477 0.55 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
glycophorin B (MNS blood group)
chr17_-_26694979 0.55 ENST00000438614.1
vitronectin
chr18_-_53177984 0.55 ENST00000543082.1
transcription factor 4
chr14_-_70263979 0.55 ENST00000216540.4
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr10_-_65028938 0.55 ENST00000402544.1
jumonji domain containing 1C
chr12_+_31812121 0.55 ENST00000395763.3
methyltransferase like 20
chr1_+_196621002 0.54 ENST00000367429.4
ENST00000439155.2
complement factor H

Network of associatons between targets according to the STRING database.

First level regulatory network of GFI1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
1.8 5.3 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
1.3 5.3 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.8 2.4 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.6 3.5 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.5 10.6 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.5 2.0 GO:2000691 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.5 1.5 GO:0098582 innate vocalization behavior(GO:0098582)
0.5 2.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.4 1.3 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.4 2.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.4 1.6 GO:0009956 radial pattern formation(GO:0009956)
0.4 1.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.4 1.1 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.3 2.4 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 1.6 GO:0070842 aggresome assembly(GO:0070842)
0.3 1.2 GO:0010842 retina layer formation(GO:0010842)
0.3 1.5 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.3 2.6 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.3 5.8 GO:0021670 lateral ventricle development(GO:0021670)
0.3 0.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.3 0.8 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.2 1.2 GO:0015811 L-cystine transport(GO:0015811)
0.2 3.9 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 1.4 GO:0043366 beta selection(GO:0043366)
0.2 1.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.2 0.9 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.2 2.6 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 1.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 0.7 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.2 0.7 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.2 0.5 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) regulation of amacrine cell differentiation(GO:1902869)
0.2 0.5 GO:0032639 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) protection from natural killer cell mediated cytotoxicity(GO:0042270) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.2 2.3 GO:0038203 TORC2 signaling(GO:0038203)
0.2 1.1 GO:0071461 cellular response to redox state(GO:0071461)
0.2 0.5 GO:0003193 pulmonary valve formation(GO:0003193) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.2 0.3 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.2 0.5 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.2 0.9 GO:0048619 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.2 0.8 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.7 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 1.0 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.9 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 3.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 2.9 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.7 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 2.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.6 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.3 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.1 0.4 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.3 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.9 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.8 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.3 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.5 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.3 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.1 4.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.3 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.5 GO:0042713 sperm ejaculation(GO:0042713)
0.1 0.3 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 1.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 4.0 GO:0010107 potassium ion import(GO:0010107)
0.1 0.6 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.6 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 0.2 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.8 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.1 2.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 6.0 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.3 GO:0039507 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 2.0 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.1 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.2 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.5 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:0021764 amygdala development(GO:0021764)
0.1 3.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.6 GO:0070997 neuron death(GO:0070997)
0.1 0.3 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.3 GO:0070884 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016) regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 1.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 6.5 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 0.2 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.1 0.6 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 1.0 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 5.6 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 0.3 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.7 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 3.3 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 2.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.0 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 1.1 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.3 GO:0050900 leukocyte migration(GO:0050900)
0.0 1.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.9 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 1.2 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 1.1 GO:0048863 stem cell differentiation(GO:0048863)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.2 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.0 1.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.6 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.9 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 1.7 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.7 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.6 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.5 GO:0030903 notochord development(GO:0030903)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.4 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.4 GO:0015866 ADP transport(GO:0015866)
0.0 0.2 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.7 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.3 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.1 GO:0071502 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.4 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.6 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.5 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 2.9 GO:0007286 spermatid development(GO:0007286)
0.0 0.8 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.2 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 1.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.3 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 1.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 2.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.2 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.2 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.1 GO:0044247 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.3 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.3 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.8 GO:0005879 axonemal microtubule(GO:0005879)
0.7 3.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.4 2.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 3.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.3 6.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 5.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.9 GO:0097224 sperm connecting piece(GO:0097224)
0.2 0.6 GO:0032302 MutSbeta complex(GO:0032302)
0.2 1.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 3.3 GO:0036038 MKS complex(GO:0036038)
0.2 0.7 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 1.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.5 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 2.3 GO:0097227 sperm annulus(GO:0097227)
0.1 0.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 3.0 GO:0071564 npBAF complex(GO:0071564)
0.1 1.6 GO:0071439 clathrin complex(GO:0071439)
0.1 2.3 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.5 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 0.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.1 GO:0043203 axon hillock(GO:0043203)
0.1 0.6 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 1.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.6 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 2.0 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.7 GO:0032009 early phagosome(GO:0032009)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.1 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 3.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 1.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.7 GO:0070578 RISC-loading complex(GO:0070578)
0.0 5.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 2.4 GO:0016235 aggresome(GO:0016235)
0.0 5.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.1 GO:0005771 multivesicular body(GO:0005771)
0.0 1.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 1.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 4.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.7 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.0 GO:0031904 endosome lumen(GO:0031904)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 2.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 1.8 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.3 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
1.9 5.8 GO:0031862 prostanoid receptor binding(GO:0031862)
1.5 6.2 GO:0061714 folic acid receptor activity(GO:0061714)
1.2 10.6 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.5 2.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.5 2.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.4 1.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.4 3.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.3 2.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 1.0 GO:0032090 Pyrin domain binding(GO:0032090)
0.3 4.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 1.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.2 3.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 0.9 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.2 0.6 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.2 0.8 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.2 5.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 0.8 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.4 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.6 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.8 GO:0097001 ceramide binding(GO:0097001)
0.1 0.5 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.6 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 2.3 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 0.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.5 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 2.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 0.5 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 1.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.3 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 2.4 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.8 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.7 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.8 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 2.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.1 GO:0070700 BMP receptor binding(GO:0070700)
0.1 2.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.5 GO:0004966 galanin receptor activity(GO:0004966)
0.1 4.2 GO:0030332 cyclin binding(GO:0030332)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.3 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 1.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.6 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.8 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.9 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.8 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 1.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.7 GO:0035197 siRNA binding(GO:0035197)
0.1 0.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.6 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 3.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 1.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.9 GO:0035198 miRNA binding(GO:0035198)
0.0 0.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 2.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 1.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 2.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.7 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.2 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.4 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 6.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.0 GO:0017129 triglyceride binding(GO:0017129)
0.0 1.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 3.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 4.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 3.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 3.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.0 PID ARF 3PATHWAY Arf1 pathway
0.0 6.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.8 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 6.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 3.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 4.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 3.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 2.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway