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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for GFI1B

Z-value: 0.56

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Transcription factors associated with GFI1B

Gene Symbol Gene ID Gene Info
GFI1B
ENSG00000165702.8 growth factor independent 1B transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GFI1Bhg19_v2_chr9_+_135854091_135854159-0.291.2e-01Click!

Activity profile of GFI1B motif

Sorted Z-values of GFI1B motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_43916296 2.51 ENST00000398352.3
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr21_-_43916433 1.78 ENST00000291536.3
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr15_+_71228826 1.70 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr20_+_56725952 1.67 ENST00000371168.3
C20orf85
chromosome 20 open reading frame 85
chr19_+_41620335 1.60 ENST00000331105.2
CYP2F1
cytochrome P450, family 2, subfamily F, polypeptide 1
chr5_-_137475071 1.36 ENST00000265191.2
NME5
NME/NM23 family member 5
chr11_+_111385497 1.18 ENST00000375618.4
ENST00000529167.1
ENST00000332814.6
C11orf88
chromosome 11 open reading frame 88
chr17_-_19281203 1.15 ENST00000487415.2
B9D1
B9 protein domain 1
chr18_+_77905894 1.13 ENST00000589574.1
ENST00000588226.1
ENST00000585422.1
AC139100.2
Uncharacterized protein
chr4_+_15471489 1.10 ENST00000424120.1
ENST00000413206.1
ENST00000438599.2
ENST00000511544.1
ENST00000512702.1
ENST00000507954.1
ENST00000515124.1
ENST00000503292.1
ENST00000503658.1
CC2D2A
coiled-coil and C2 domain containing 2A
chr11_+_71791849 1.02 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr3_-_158450231 1.00 ENST00000479756.1
RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr3_-_158450475 0.92 ENST00000237696.5
RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr11_+_71791693 0.88 ENST00000289488.2
ENST00000447974.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr11_+_101785727 0.86 ENST00000263468.8
KIAA1377
KIAA1377
chr5_+_36608422 0.84 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_+_140261703 0.82 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr11_+_71791803 0.79 ENST00000539271.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr4_+_39184024 0.76 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
WDR19
WD repeat domain 19
chr19_-_51412584 0.75 ENST00000431178.2
KLK4
kallikrein-related peptidase 4
chr7_-_6007070 0.71 ENST00000337579.3
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chr7_+_6796986 0.71 ENST00000297186.3
RSPH10B2
radial spoke head 10 homolog B2 (Chlamydomonas)
chr16_-_18441131 0.70 ENST00000339303.5
NPIPA8
nuclear pore complex interacting protein family, member A8
chr7_-_150721570 0.70 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
ATG9B
autophagy related 9B
chr5_-_124080203 0.69 ENST00000504926.1
ZNF608
zinc finger protein 608
chr11_+_27076764 0.68 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr5_-_96478466 0.63 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr4_+_41362796 0.60 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1
LIM and calponin homology domains 1
chr3_+_184055240 0.59 ENST00000383847.2
FAM131A
family with sequence similarity 131, member A
chr7_-_138363824 0.58 ENST00000419765.3
SVOPL
SVOP-like
chr12_+_124155652 0.58 ENST00000426174.2
ENST00000303372.5
TCTN2
tectonic family member 2
chr14_-_106069247 0.57 ENST00000479229.1
RP11-731F5.1
RP11-731F5.1
chr19_+_36236491 0.57 ENST00000591949.1
PSENEN
presenilin enhancer gamma secretase subunit
chr19_+_36236514 0.56 ENST00000222266.2
PSENEN
presenilin enhancer gamma secretase subunit
chr20_+_58179582 0.55 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr19_-_48823332 0.54 ENST00000315396.7
CCDC114
coiled-coil domain containing 114
chr11_+_60197069 0.53 ENST00000528905.1
ENST00000528093.1
MS4A5
membrane-spanning 4-domains, subfamily A, member 5
chr8_-_12668962 0.52 ENST00000534827.1
RP11-252C15.1
RP11-252C15.1
chr20_+_32254286 0.50 ENST00000330271.4
ACTL10
actin-like 10
chr5_+_98109322 0.48 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr2_+_162272605 0.48 ENST00000389554.3
TBR1
T-box, brain, 1
chr1_+_210406121 0.48 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr21_-_47743719 0.47 ENST00000397680.1
ENST00000445935.1
ENST00000397685.4
ENST00000397682.3
ENST00000291691.7
C21orf58
chromosome 21 open reading frame 58
chr10_-_102279586 0.46 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31B
SEC31 homolog B (S. cerevisiae)
chr10_-_13523073 0.45 ENST00000440282.1
BEND7
BEN domain containing 7
chr16_+_4838412 0.45 ENST00000589327.1
SMIM22
small integral membrane protein 22
chr6_-_161695042 0.44 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr19_+_17337473 0.44 ENST00000598068.1
OCEL1
occludin/ELL domain containing 1
chr7_+_120591170 0.43 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr10_+_94590910 0.41 ENST00000371547.4
EXOC6
exocyst complex component 6
chr3_+_125694347 0.40 ENST00000505382.1
ENST00000511082.1
ROPN1B
rhophilin associated tail protein 1B
chr14_-_23285069 0.39 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr6_-_31648150 0.39 ENST00000375858.3
ENST00000383237.4
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr16_-_18468926 0.39 ENST00000545114.1
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr14_-_23285011 0.39 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr6_+_90272027 0.38 ENST00000522441.1
ANKRD6
ankyrin repeat domain 6
chr6_-_56707943 0.38 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST
dystonin
chr2_-_96874553 0.37 ENST00000337288.5
ENST00000443962.1
STARD7
StAR-related lipid transfer (START) domain containing 7
chr3_-_187454281 0.37 ENST00000232014.4
BCL6
B-cell CLL/lymphoma 6
chr19_+_36602104 0.37 ENST00000585332.1
ENST00000262637.4
OVOL3
ovo-like zinc finger 3
chr15_-_49255632 0.37 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr16_+_30212378 0.36 ENST00000569485.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr1_-_173638976 0.36 ENST00000333279.2
ANKRD45
ankyrin repeat domain 45
chr6_-_161695074 0.36 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr3_-_190580404 0.35 ENST00000442080.1
GMNC
geminin coiled-coil domain containing
chr12_+_50017327 0.34 ENST00000261897.1
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr19_-_17571722 0.34 ENST00000301944.2
NXNL1
nucleoredoxin-like 1
chr21_-_34185944 0.33 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr18_+_48494361 0.32 ENST00000588577.1
ENST00000269466.3
ENST00000591429.1
ENST00000452201.2
ELAC1
SMAD4
elaC ribonuclease Z 1
SMAD family member 4
chr16_+_4838393 0.31 ENST00000589721.1
SMIM22
small integral membrane protein 22
chr15_-_27184664 0.30 ENST00000541819.2
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr11_-_94964354 0.30 ENST00000536441.1
SESN3
sestrin 3
chr1_+_45965725 0.29 ENST00000401061.4
MMACHC
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr17_-_9929581 0.29 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr15_-_90645679 0.29 ENST00000539790.1
ENST00000559482.1
ENST00000330062.3
IDH2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr1_+_164528866 0.29 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr16_+_29472707 0.28 ENST00000565290.1
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr1_+_177140633 0.28 ENST00000361539.4
BRINP2
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr7_+_120590803 0.27 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
ING3
inhibitor of growth family, member 3
chr6_-_36842784 0.27 ENST00000373699.5
PPIL1
peptidylprolyl isomerase (cyclophilin)-like 1
chrX_+_129473916 0.27 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr5_+_133451254 0.27 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr11_-_85397167 0.27 ENST00000316398.3
CCDC89
coiled-coil domain containing 89
chr17_-_79995553 0.27 ENST00000581584.1
ENST00000577712.1
ENST00000582900.1
ENST00000579155.1
ENST00000306869.2
DCXR
dicarbonyl/L-xylulose reductase
chr3_-_93781750 0.26 ENST00000314636.2
DHFRL1
dihydrofolate reductase-like 1
chr19_-_45681482 0.26 ENST00000592647.1
ENST00000006275.4
ENST00000588062.1
ENST00000585934.1
TRAPPC6A
trafficking protein particle complex 6A
chr6_+_32821924 0.26 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr19_-_46389359 0.26 ENST00000302165.3
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr9_-_123239632 0.26 ENST00000416449.1
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr12_+_50017184 0.26 ENST00000548825.2
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr1_+_15272271 0.26 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr1_+_204839959 0.25 ENST00000404076.1
NFASC
neurofascin
chr18_-_30050395 0.25 ENST00000269209.6
ENST00000399218.4
GAREM
GRB2 associated, regulator of MAPK1
chr16_+_15039742 0.24 ENST00000537062.1
NPIPA1
nuclear pore complex interacting protein family, member A1
chr19_+_58258164 0.24 ENST00000317178.5
ZNF776
zinc finger protein 776
chr13_-_67802549 0.24 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr12_+_109273806 0.24 ENST00000228476.3
ENST00000547768.1
DAO
D-amino-acid oxidase
chr7_+_123488124 0.24 ENST00000476325.1
HYAL4
hyaluronoglucosaminidase 4
chr22_+_45072958 0.23 ENST00000403581.1
PRR5
proline rich 5 (renal)
chr6_-_56708459 0.23 ENST00000370788.2
DST
dystonin
chr22_+_45072925 0.23 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr11_+_35684288 0.23 ENST00000299413.5
TRIM44
tripartite motif containing 44
chr19_-_10687907 0.23 ENST00000589348.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr11_+_119056178 0.23 ENST00000525131.1
ENST00000531114.1
ENST00000355547.5
ENST00000322712.4
PDZD3
PDZ domain containing 3
chr11_-_68780824 0.23 ENST00000441623.1
ENST00000309099.6
MRGPRF
MAS-related GPR, member F
chr19_+_55477711 0.23 ENST00000448584.2
ENST00000537859.1
ENST00000585500.1
ENST00000427260.2
ENST00000538819.1
ENST00000263437.6
NLRP2
NLR family, pyrin domain containing 2
chr2_+_61372226 0.23 ENST00000426997.1
C2orf74
chromosome 2 open reading frame 74
chr3_+_152017924 0.23 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
MBNL1
muscleblind-like splicing regulator 1
chr10_+_71211212 0.23 ENST00000373290.2
TSPAN15
tetraspanin 15
chr16_+_50775948 0.22 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr1_+_182419261 0.22 ENST00000294854.8
ENST00000542961.1
RGSL1
regulator of G-protein signaling like 1
chr4_-_156875003 0.22 ENST00000433477.3
CTSO
cathepsin O
chr1_+_164529004 0.22 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1
pre-B-cell leukemia homeobox 1
chr1_+_15943995 0.22 ENST00000480945.1
DDI2
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr19_+_7069690 0.22 ENST00000439035.2
ZNF557
zinc finger protein 557
chr4_+_154125565 0.21 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr2_-_158732340 0.21 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
ACVR1
activin A receptor, type I
chr20_+_52105495 0.21 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr1_-_10856694 0.21 ENST00000377022.3
ENST00000344008.5
CASZ1
castor zinc finger 1
chr3_-_172312460 0.21 ENST00000418839.2
RP11-408H1.3
RP11-408H1.3
chr7_+_107110488 0.21 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr2_+_47630108 0.20 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2
mutS homolog 2
chr4_+_76995855 0.19 ENST00000355810.4
ENST00000349321.3
ART3
ADP-ribosyltransferase 3
chrX_-_48056199 0.19 ENST00000311798.1
ENST00000347757.1
SSX5
synovial sarcoma, X breakpoint 5
chr2_-_45236540 0.19 ENST00000303077.6
SIX2
SIX homeobox 2
chr6_+_44215603 0.19 ENST00000371554.1
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr13_+_113623509 0.19 ENST00000535094.2
MCF2L
MCF.2 cell line derived transforming sequence-like
chr11_-_33774944 0.19 ENST00000532057.1
ENST00000531080.1
FBXO3
F-box protein 3
chr22_+_41865109 0.18 ENST00000216254.4
ENST00000396512.3
ACO2
aconitase 2, mitochondrial
chr1_-_13007420 0.18 ENST00000376189.1
PRAMEF6
PRAME family member 6
chr1_-_23886285 0.18 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr10_+_88516396 0.17 ENST00000372037.3
BMPR1A
bone morphogenetic protein receptor, type IA
chr7_+_142364193 0.17 ENST00000390397.2
TRBV24-1
T cell receptor beta variable 24-1
chr11_-_62420757 0.17 ENST00000330574.2
INTS5
integrator complex subunit 5
chr1_+_39796810 0.17 ENST00000289893.4
MACF1
microtubule-actin crosslinking factor 1
chr1_-_49242553 0.17 ENST00000371833.3
BEND5
BEN domain containing 5
chr5_+_56111361 0.17 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr1_-_13005246 0.17 ENST00000415464.2
PRAMEF6
PRAME family member 6
chr7_+_150758304 0.17 ENST00000482950.1
ENST00000463414.1
ENST00000310317.5
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr6_-_116381918 0.17 ENST00000606080.1
FRK
fyn-related kinase
chr9_-_110540419 0.17 ENST00000398726.3
AL162389.1
Uncharacterized protein
chr14_+_77228532 0.16 ENST00000167106.4
ENST00000554237.1
VASH1
vasohibin 1
chr6_+_107077435 0.16 ENST00000369046.4
QRSL1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr19_-_35719609 0.16 ENST00000324675.3
FAM187B
family with sequence similarity 187, member B
chr12_+_53835508 0.16 ENST00000551003.1
ENST00000549068.1
ENST00000549740.1
ENST00000546581.1
ENST00000549581.1
ENST00000541275.1
PRR13
PCBP2
proline rich 13
poly(rC) binding protein 2
chr7_+_73106926 0.16 ENST00000453316.1
WBSCR22
Williams Beuren syndrome chromosome region 22
chr17_-_7218631 0.16 ENST00000577040.2
ENST00000389167.5
ENST00000391950.3
GPS2
G protein pathway suppressor 2
chr19_+_57862622 0.15 ENST00000391705.3
ENST00000443917.2
ENST00000598744.1
ZNF304
zinc finger protein 304
chr16_+_19183671 0.15 ENST00000562711.2
SYT17
synaptotagmin XVII
chr9_+_35538616 0.15 ENST00000455600.1
RUSC2
RUN and SH3 domain containing 2
chr1_-_19615744 0.15 ENST00000361640.4
AKR7A3
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
chr1_+_13359819 0.15 ENST00000376168.1
PRAMEF5
PRAME family member 5
chr14_+_78870030 0.15 ENST00000553631.1
ENST00000554719.1
NRXN3
neurexin 3
chr17_+_36858694 0.15 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr1_+_109102652 0.15 ENST00000370035.3
ENST00000405454.1
FAM102B
family with sequence similarity 102, member B
chr1_+_14075903 0.15 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PRDM2
PR domain containing 2, with ZNF domain
chr20_-_35274548 0.15 ENST00000262866.4
SLA2
Src-like-adaptor 2
chr12_+_53835383 0.15 ENST00000429243.2
PRR13
proline rich 13
chr14_+_105957402 0.14 ENST00000421892.1
ENST00000334656.7
ENST00000451719.1
ENST00000392522.3
ENST00000392523.4
ENST00000354560.6
ENST00000450383.1
C14orf80
chromosome 14 open reading frame 80
chr16_-_75301886 0.14 ENST00000393422.2
BCAR1
breast cancer anti-estrogen resistance 1
chr9_-_70488865 0.14 ENST00000377392.5
CBWD5
COBW domain containing 5
chr5_-_137071756 0.14 ENST00000394937.3
ENST00000309755.4
KLHL3
kelch-like family member 3
chr17_+_3100813 0.14 ENST00000381951.1
OR1A2
olfactory receptor, family 1, subfamily A, member 2
chr8_+_62200509 0.14 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
CLVS1
clavesin 1
chr12_+_53835539 0.14 ENST00000547368.1
ENST00000379786.4
ENST00000551945.1
PRR13
proline rich 13
chr16_+_30675654 0.14 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr2_-_9563575 0.13 ENST00000488451.1
ENST00000238091.4
ENST00000355346.4
ITGB1BP1
integrin beta 1 binding protein 1
chr7_-_99332719 0.13 ENST00000336374.2
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
chr19_-_44124019 0.13 ENST00000300811.3
ZNF428
zinc finger protein 428
chr2_+_242295658 0.13 ENST00000264042.3
ENST00000545004.1
ENST00000373287.4
FARP2
FERM, RhoGEF and pleckstrin domain protein 2
chr12_+_48513009 0.13 ENST00000359794.5
ENST00000551339.1
ENST00000395233.2
ENST00000548345.1
PFKM
phosphofructokinase, muscle
chr10_+_45455207 0.13 ENST00000334940.6
ENST00000374417.2
ENST00000340258.5
ENST00000427758.1
RASSF4
Ras association (RalGDS/AF-6) domain family member 4
chr21_-_43430440 0.13 ENST00000398505.3
ENST00000310826.5
ENST00000449949.1
ENST00000398499.1
ENST00000398497.2
ENST00000398511.3
ZBTB21
zinc finger and BTB domain containing 21
chr16_-_4838255 0.13 ENST00000591624.1
ENST00000396693.5
SEPT12
septin 12
chr1_-_182360918 0.13 ENST00000339526.4
GLUL
glutamate-ammonia ligase
chr16_+_50775971 0.13 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD
cylindromatosis (turban tumor syndrome)
chr19_+_11649532 0.13 ENST00000252456.2
ENST00000592923.1
ENST00000535659.2
CNN1
calponin 1, basic, smooth muscle
chr19_+_11455900 0.13 ENST00000588790.1
CCDC159
coiled-coil domain containing 159
chr5_+_37379314 0.13 ENST00000265107.4
ENST00000504564.1
WDR70
WD repeat domain 70
chr11_+_61717336 0.12 ENST00000378042.3
BEST1
bestrophin 1
chr1_-_13002348 0.12 ENST00000355096.2
PRAMEF6
PRAME family member 6
chr2_+_202122703 0.12 ENST00000447616.1
ENST00000358485.4
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr1_+_158325684 0.12 ENST00000368162.2
CD1E
CD1e molecule
chr17_+_61699766 0.12 ENST00000579585.1
ENST00000584573.1
ENST00000361733.3
ENST00000361357.3
MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr17_-_56595196 0.12 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
MTMR4
myotubularin related protein 4
chr2_+_26915584 0.12 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr13_+_111806055 0.12 ENST00000218789.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr20_+_47835884 0.12 ENST00000371764.4
DDX27
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr1_-_182361327 0.11 ENST00000331872.6
ENST00000311223.5
GLUL
glutamate-ammonia ligase
chr14_-_64108125 0.11 ENST00000267522.3
WDR89
WD repeat domain 89
chr12_+_48513570 0.11 ENST00000551804.1
PFKM
phosphofructokinase, muscle
chr11_-_5173599 0.11 ENST00000328942.1
OR52A1
olfactory receptor, family 52, subfamily A, member 1
chr12_-_70093190 0.11 ENST00000330891.5
BEST3
bestrophin 3
chr1_+_226736446 0.11 ENST00000366788.3
ENST00000366789.4
C1orf95
chromosome 1 open reading frame 95
chr3_+_152017360 0.11 ENST00000485910.1
ENST00000463374.1
MBNL1
muscleblind-like splicing regulator 1
chr4_+_160188889 0.11 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr10_+_24498060 0.11 ENST00000376454.3
ENST00000376452.3
KIAA1217
KIAA1217
chr2_+_69201705 0.11 ENST00000377938.2
GKN1
gastrokine 1
chr10_+_24528108 0.10 ENST00000438429.1
KIAA1217
KIAA1217
chr9_-_115819039 0.10 ENST00000555206.1
ZFP37
ZFP37 zinc finger protein

Network of associatons between targets according to the STRING database.

First level regulatory network of GFI1B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.2 0.7 GO:0044805 late nucleophagy(GO:0044805)
0.2 1.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 3.0 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.1 0.8 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.1 0.4 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.8 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 1.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.3 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.1 0.4 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.3 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.6 GO:0021764 amygdala development(GO:0021764)
0.1 0.3 GO:0042732 D-xylose metabolic process(GO:0042732)
0.1 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 4.8 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.2 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.1 0.2 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 0.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 1.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.3 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 1.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.2 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0048378 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.0 0.2 GO:0044467 glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.0 0.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:0052148 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309) positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.0 0.1 GO:0046707 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.8 GO:0097186 amelogenesis(GO:0097186)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 1.2 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 1.2 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.5 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.1 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.6 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.0 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.1 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.3 GO:0072687 meiotic spindle(GO:0072687)
0.2 0.6 GO:0031673 H zone(GO:0031673)
0.1 2.8 GO:0036038 MKS complex(GO:0036038)
0.1 1.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.2 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.3 GO:0097386 glial cell projection(GO:0097386)
0.0 0.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.4 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.2 0.7 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 1.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.3 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.2 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 1.7 GO:0070330 aromatase activity(GO:0070330)
0.1 0.2 GO:0032181 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.2 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.2 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.4 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.3 GO:0043199 sulfate binding(GO:0043199)
0.1 0.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 1.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.4 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.1 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10