Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for GGAAUGU
Z-value: 0.40
Motif logo
miRNA associated with seed GGAAUGU
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_+_4382917 Show fit | 1.14 |
ENST00000261254.3
|
cyclin D2 |
|
| chr5_-_172756506 Show fit | 0.82 |
ENST00000265087.4
|
stanniocalcin 2 |
|
| chr4_-_111119804 Show fit | 0.62 |
ENST00000394607.3
ENST00000302274.3 |
ELOVL fatty acid elongase 6 |
|
| chr14_+_20937538 Show fit | 0.54 |
ENST00000361505.5
ENST00000553591.1 |
purine nucleoside phosphorylase |
|
| chr17_-_53499310 Show fit | 0.49 |
ENST00000262065.3
|
monocyte to macrophage differentiation-associated |
|
| chr15_+_39873268 Show fit | 0.48 |
ENST00000397591.2
ENST00000260356.5 |
thrombospondin 1 |
|
| chr3_-_123603137 Show fit | 0.42 |
ENST00000360304.3
ENST00000359169.1 ENST00000346322.5 ENST00000360772.3 |
myosin light chain kinase |
|
| chr10_+_102106829 Show fit | 0.42 |
ENST00000370355.2
|
stearoyl-CoA desaturase (delta-9-desaturase) |
|
| chr17_+_70117153 Show fit | 0.42 |
ENST00000245479.2
|
SRY (sex determining region Y)-box 9 |
|
| chr1_-_179198702 Show fit | 0.36 |
ENST00000502732.1
|
c-abl oncogene 2, non-receptor tyrosine kinase |
Network of associatons between targets according to the STRING database.
First level regulatory network of GGAAUGU
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | GO:0071481 | cellular response to X-ray(GO:0071481) |
| 0.1 | 0.8 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.1 | 0.6 | GO:1904628 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.1 | 0.6 | GO:0019367 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.2 | 0.5 | GO:0070638 | nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638) |
| 0.2 | 0.5 | GO:0002605 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) |
| 0.1 | 0.4 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
| 0.1 | 0.4 | GO:0072034 | primary prostatic bud elongation(GO:0060516) renal vesicle induction(GO:0072034) |
| 0.1 | 0.4 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
| 0.0 | 0.4 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.3 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.0 | 0.8 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 0.7 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.0 | 0.5 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 0.3 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.0 | 0.3 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.0 | 0.3 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.0 | 0.3 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.0 | 0.3 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 0.3 | GO:0097431 | mitotic spindle pole(GO:0097431) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 0.6 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.2 | 0.5 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
| 0.2 | 0.5 | GO:0070052 | collagen V binding(GO:0070052) |
| 0.0 | 0.5 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 0.4 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.0 | 0.4 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.0 | 0.4 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.0 | 0.4 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.0 | 0.4 | GO:0015245 | fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 0.8 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.5 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.5 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 0.4 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 0.4 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.0 | 0.3 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.0 | 0.2 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.0 | 0.1 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 0.1 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.8 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 0.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.5 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.0 | 0.5 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 0.4 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.0 | 0.3 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 0.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.2 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.0 | 0.2 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |