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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for GGCAGUG

Z-value: 0.88

Motif logo

miRNA associated with seed GGCAGUG

NamemiRBASE accession
MIMAT0000255
MIMAT0000686
MIMAT0001541
MIMAT0003327

Activity profile of GGCAGUG motif

Sorted Z-values of GGCAGUG motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_100770328 4.01 ENST00000223095.4
ENST00000445463.2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr19_+_54371114 2.25 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
myeloid-associated differentiation marker
chr2_+_48541776 1.99 ENST00000413569.1
ENST00000340553.3
forkhead box N2
chr12_-_95044309 1.94 ENST00000261226.4
transmembrane and coiled-coil domain family 3
chr19_-_50143452 1.84 ENST00000246792.3
related RAS viral (r-ras) oncogene homolog
chr17_-_41174424 1.75 ENST00000355653.3
vesicle amine transport 1
chr19_-_2783363 1.63 ENST00000221566.2
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr19_+_41725088 1.62 ENST00000301178.4
AXL receptor tyrosine kinase
chr7_+_145813453 1.36 ENST00000361727.3
contactin associated protein-like 2
chr19_-_49015050 1.35 ENST00000600059.1
lemur tyrosine kinase 3
chr4_+_99182593 1.22 ENST00000508213.1
ENST00000408927.3
ENST00000514122.1
ENST00000453712.2
ENST00000511212.1
ENST00000408900.3
ENST00000339360.5
RAP1, GTP-GDP dissociation stimulator 1
chr9_-_123639600 1.19 ENST00000373896.3
PHD finger protein 19
chr12_+_107712173 1.19 ENST00000280758.5
ENST00000420571.2
BTB (POZ) domain containing 11
chr4_+_75480629 1.13 ENST00000380846.3
amphiregulin B
chr12_+_1800179 1.13 ENST00000357103.4
adiponectin receptor 2
chr1_+_84543734 1.09 ENST00000370689.2
protein kinase, cAMP-dependent, catalytic, beta
chr16_-_4588822 1.01 ENST00000564828.1
cell death-inducing p53 target 1
chr8_+_11141925 0.99 ENST00000221086.3
myotubularin related protein 9
chr17_+_61086917 0.95 ENST00000424789.2
ENST00000389520.4
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr2_-_208030647 0.94 ENST00000309446.6
Kruppel-like factor 7 (ubiquitous)
chr15_+_90744533 0.94 ENST00000411539.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr20_-_10654639 0.91 ENST00000254958.5
jagged 1
chr1_+_165796753 0.91 ENST00000367879.4
uridine-cytidine kinase 2
chr11_-_119599794 0.90 ENST00000264025.3
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr6_-_75915757 0.90 ENST00000322507.8
collagen, type XII, alpha 1
chr12_+_107168342 0.89 ENST00000392837.4
RIC8 guanine nucleotide exchange factor B
chr1_+_178694300 0.88 ENST00000367635.3
Ral GEF with PH domain and SH3 binding motif 2
chr22_+_51112800 0.88 ENST00000414786.2
SH3 and multiple ankyrin repeat domains 3
chr9_+_131102925 0.88 ENST00000372870.1
ENST00000300456.4
solute carrier family 27 (fatty acid transporter), member 4
chr19_-_14629224 0.87 ENST00000254322.2
DnaJ (Hsp40) homolog, subfamily B, member 1
chr17_-_71640227 0.85 ENST00000388726.3
ENST00000392650.3
sidekick cell adhesion molecule 2
chr5_+_149887672 0.84 ENST00000261797.6
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr11_+_117049445 0.83 ENST00000324225.4
ENST00000532960.1
SID1 transmembrane family, member 2
chr14_-_99737565 0.82 ENST00000357195.3
B-cell CLL/lymphoma 11B (zinc finger protein)
chr15_+_66679155 0.80 ENST00000307102.5
mitogen-activated protein kinase kinase 1
chr19_+_7895074 0.80 ENST00000270530.4
ecotropic viral integration site 5-like
chr2_-_220094294 0.78 ENST00000436856.1
ENST00000428226.1
ENST00000409422.1
ENST00000431715.1
ENST00000457841.1
ENST00000439812.1
ENST00000361242.4
ENST00000396761.2
autophagy related 9A
chr2_+_74881355 0.78 ENST00000357877.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr19_-_46296011 0.77 ENST00000377735.3
ENST00000270223.6
dystrophia myotonica, WD repeat containing
chr1_+_31769836 0.75 ENST00000344147.5
ENST00000373714.1
ENST00000546109.1
ENST00000422613.2
zinc finger, CCHC domain containing 17
chr14_-_68162464 0.75 ENST00000553384.1
ENST00000557726.1
ENST00000381346.4
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr2_+_24272543 0.75 ENST00000380991.4
FK506 binding protein 1B, 12.6 kDa
chr11_+_60681346 0.74 ENST00000227525.3
transmembrane protein 109
chr7_-_92463210 0.74 ENST00000265734.4
cyclin-dependent kinase 6
chr12_-_109125285 0.73 ENST00000552871.1
ENST00000261401.3
coronin, actin binding protein, 1C
chr11_+_65405556 0.73 ENST00000534313.1
ENST00000533361.1
ENST00000526137.1
signal-induced proliferation-associated 1
chr9_+_124413873 0.70 ENST00000408936.3
DAB2 interacting protein
chr2_-_122042770 0.69 ENST00000263707.5
transcription factor CP2-like 1
chr1_-_39325431 0.68 ENST00000373001.3
Ras-related GTP binding C
chr8_+_42752053 0.67 ENST00000307602.4
hook microtubule-tethering protein 3
chr10_+_75936444 0.66 ENST00000372734.3
ENST00000541550.1
adenosine kinase
chr15_-_42264702 0.66 ENST00000220325.4
EH-domain containing 4
chr6_+_46620676 0.65 ENST00000371347.5
ENST00000411689.2
solute carrier family 25, member 27
chr22_-_36784035 0.63 ENST00000216181.5
myosin, heavy chain 9, non-muscle
chr5_+_172261228 0.63 ENST00000393784.3
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr15_+_79724858 0.62 ENST00000305428.3
KIAA1024
chr3_-_48229846 0.61 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
cell division cycle 25A
chr8_-_60031762 0.60 ENST00000361421.1
thymocyte selection-associated high mobility group box
chr15_+_91473403 0.60 ENST00000394275.2
unc-45 homolog A (C. elegans)
chr5_-_150948414 0.60 ENST00000261800.5
FAT atypical cadherin 2
chr14_-_64194745 0.59 ENST00000247225.6
sphingosine-1-phosphate phosphatase 1
chr2_-_166930131 0.58 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
sodium channel, voltage-gated, type I, alpha subunit
chr16_+_56225248 0.57 ENST00000262493.6
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr10_+_105036909 0.57 ENST00000369849.4
internexin neuronal intermediate filament protein, alpha
chr2_+_45168875 0.57 ENST00000260653.3
SIX homeobox 3
chr17_-_31620006 0.55 ENST00000225823.2
acid-sensing (proton-gated) ion channel 2
chr5_+_175223313 0.55 ENST00000359546.4
complexin 2
chr1_+_11994715 0.55 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr7_+_128864848 0.54 ENST00000325006.3
ENST00000446544.2
adenosylhomocysteinase-like 2
chr11_-_65667884 0.53 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOS-like antigen 1
chr9_-_136242909 0.53 ENST00000371991.3
ENST00000545297.1
surfeit 4
chr10_+_99205959 0.52 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
zinc finger, DHHC-type containing 16
chr22_-_37099555 0.52 ENST00000300105.6
calcium channel, voltage-dependent, gamma subunit 2
chr5_-_132299313 0.52 ENST00000265343.5
AF4/FMR2 family, member 4
chr3_-_172428959 0.51 ENST00000475381.1
ENST00000538775.1
ENST00000273512.3
ENST00000543711.1
neutral cholesterol ester hydrolase 1
chr3_+_25469724 0.50 ENST00000437042.2
retinoic acid receptor, beta
chr3_-_113465065 0.50 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr6_-_110500905 0.50 ENST00000392587.2
WAS protein family, member 1
chr19_-_2456922 0.49 ENST00000582871.1
ENST00000325327.3
lamin B2
chr3_-_176914238 0.48 ENST00000430069.1
ENST00000428970.1
transducin (beta)-like 1 X-linked receptor 1
chr3_+_171758344 0.48 ENST00000336824.4
ENST00000423424.1
fibronectin type III domain containing 3B
chr9_-_139440314 0.48 ENST00000277541.6
notch 1
chr8_+_102504651 0.48 ENST00000251808.3
ENST00000521085.1
grainyhead-like 2 (Drosophila)
chr10_-_71930222 0.47 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1 homolog A (S. cerevisiae)
chr5_+_133861790 0.46 ENST00000395003.1
jade family PHD finger 2
chr15_+_71389281 0.45 ENST00000355327.3
thrombospondin, type I, domain containing 4
chr6_+_96463840 0.44 ENST00000302103.5
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chrX_-_118284542 0.43 ENST00000402510.2
KIAA1210
chr12_-_95611149 0.43 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FYVE, RhoGEF and PH domain containing 6
chr11_+_69455855 0.43 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr13_-_25746416 0.42 ENST00000515384.1
ENST00000357816.2
APC membrane recruitment protein 2
chr4_+_55095264 0.42 ENST00000257290.5
platelet-derived growth factor receptor, alpha polypeptide
chr22_-_38669030 0.42 ENST00000361906.3
transmembrane protein 184B
chr20_+_62371206 0.42 ENST00000266077.2
SLC2A4 regulator
chr16_-_89007491 0.42 ENST00000327483.5
ENST00000564416.1
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr16_+_81069433 0.42 ENST00000299575.4
ATM interactor
chr4_-_109089573 0.41 ENST00000265165.1
lymphoid enhancer-binding factor 1
chr17_+_43971643 0.41 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
microtubule-associated protein tau
chr9_-_110251836 0.41 ENST00000374672.4
Kruppel-like factor 4 (gut)
chr11_-_2906979 0.40 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr4_+_144257915 0.40 ENST00000262995.4
GRB2-associated binding protein 1
chr11_-_118047376 0.40 ENST00000278947.5
sodium channel, voltage-gated, type II, beta subunit
chr9_+_103204553 0.40 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr17_+_1646130 0.40 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr8_-_66754172 0.39 ENST00000401827.3
phosphodiesterase 7A
chr1_+_197881592 0.39 ENST00000367391.1
ENST00000367390.3
LIM homeobox 9
chr17_-_61777459 0.39 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIM domain containing 2
chr11_-_67236691 0.39 ENST00000544903.1
ENST00000308022.2
ENST00000393877.3
ENST00000452789.2
transmembrane protein 134
chr8_-_11324273 0.39 ENST00000284486.4
family with sequence similarity 167, member A
chr7_+_138916231 0.38 ENST00000473989.3
ENST00000288561.8
ubinuclein 2
chr19_-_10514184 0.38 ENST00000589629.1
ENST00000222005.2
cell division cycle 37
chr2_-_163695128 0.38 ENST00000332142.5
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr11_+_65837907 0.37 ENST00000320580.4
phosphofurin acidic cluster sorting protein 1
chr8_+_28174649 0.37 ENST00000301908.3
prepronociceptin
chr4_+_113970772 0.36 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ankyrin 2, neuronal
chr3_-_27498235 0.36 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr1_-_21978312 0.36 ENST00000359708.4
ENST00000290101.4
RAP1 GTPase activating protein
chr19_-_41196534 0.36 ENST00000252891.4
numb homolog (Drosophila)-like
chrX_+_118108571 0.36 ENST00000304778.7
LON peptidase N-terminal domain and ring finger 3
chr17_-_27224621 0.35 ENST00000394906.2
ENST00000585169.1
ENST00000394908.4
flotillin 2
chr1_+_160175117 0.35 ENST00000360472.4
phosphoprotein enriched in astrocytes 15
chr6_-_43543702 0.35 ENST00000265351.7
exportin 5
chr9_-_101471479 0.35 ENST00000259455.2
gamma-aminobutyric acid (GABA) B receptor, 2
chr17_+_1182948 0.34 ENST00000333813.3
tumor suppressor candidate 5
chr3_-_179754706 0.34 ENST00000465751.1
ENST00000467460.1
peroxisomal biogenesis factor 5-like
chr8_-_4852218 0.34 ENST00000400186.3
ENST00000602723.1
CUB and Sushi multiple domains 1
chr10_-_104262426 0.34 ENST00000487599.1
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr2_-_97405775 0.34 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
lectin, mannose-binding 2-like
chr9_+_103235365 0.34 ENST00000374879.4
transmembrane protein with EGF-like and two follistatin-like domains 1
chr1_-_161014731 0.33 ENST00000368020.1
upstream transcription factor 1
chr5_+_176560742 0.33 ENST00000439151.2
nuclear receptor binding SET domain protein 1
chr12_-_27167233 0.32 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
transmembrane 7 superfamily member 3
chr11_-_64410787 0.31 ENST00000301894.2
neurexin 2
chr7_+_2443202 0.31 ENST00000258711.6
carbohydrate (chondroitin 4) sulfotransferase 12
chr15_-_44486632 0.30 ENST00000484674.1
FERM domain containing 5
chr11_-_64901978 0.30 ENST00000294256.8
ENST00000377190.3
synovial apoptosis inhibitor 1, synoviolin
chr3_-_184870751 0.30 ENST00000335012.2
chromosome 3 open reading frame 70
chr11_+_18416133 0.30 ENST00000227157.4
ENST00000478970.2
ENST00000495052.1
lactate dehydrogenase A
chr11_+_64126614 0.30 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr1_-_156542328 0.30 ENST00000361170.2
IQ motif containing GTPase activating protein 3
chr12_-_57030115 0.30 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
bromodomain adjacent to zinc finger domain, 2A
chr4_+_124320665 0.30 ENST00000394339.2
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr11_-_9025541 0.29 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
nuclear receptor interacting protein 3
chr10_-_15210666 0.29 ENST00000378165.4
N-myristoyltransferase 2
chr10_+_71078595 0.29 ENST00000359426.6
hexokinase 1
chr1_+_205012293 0.28 ENST00000331830.4
contactin 2 (axonal)
chr12_-_49504655 0.28 ENST00000551782.1
ENST00000267102.8
limb development membrane protein 1-like
chr6_+_21593972 0.28 ENST00000244745.1
ENST00000543472.1
SRY (sex determining region Y)-box 4
chr15_+_38544476 0.28 ENST00000299084.4
sprouty-related, EVH1 domain containing 1
chr10_+_82213904 0.28 ENST00000429989.3
tetraspanin 14
chr17_-_4269768 0.28 ENST00000396981.2
ubiquitin-conjugating enzyme E2G 1
chr9_-_104249319 0.28 ENST00000374847.1
transmembrane protein 246
chr3_+_38206975 0.27 ENST00000446845.1
ENST00000311806.3
oxidative stress responsive 1
chr7_-_143059845 0.26 ENST00000443739.2
family with sequence similarity 131, member B
chr11_+_74660278 0.26 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr11_+_46354455 0.26 ENST00000343674.6
diacylglycerol kinase, zeta
chr1_+_231297798 0.26 ENST00000444294.3
tripartite motif containing 67
chr1_+_64058939 0.26 ENST00000371084.3
phosphoglucomutase 1
chr2_+_120517174 0.26 ENST00000263708.2
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr13_-_27334879 0.26 ENST00000405846.3
G protein-coupled receptor 12
chr2_+_43864387 0.26 ENST00000282406.4
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr22_+_29469012 0.25 ENST00000400335.4
ENST00000400338.2
kringle containing transmembrane protein 1
chr1_-_226374373 0.25 ENST00000366812.5
acyl-CoA binding domain containing 3
chr12_+_112563335 0.25 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAF-type zinc finger domain containing 1
chr6_-_30585009 0.25 ENST00000376511.2
protein phosphatase 1, regulatory subunit 10
chr10_-_118032697 0.25 ENST00000439649.3
GDNF family receptor alpha 1
chr6_-_6007200 0.24 ENST00000244766.2
neuritin 1
chr3_+_39851094 0.24 ENST00000302541.6
myosin VIIA and Rab interacting protein
chr2_-_100721178 0.24 ENST00000409236.2
AF4/FMR2 family, member 3
chr14_+_100705322 0.24 ENST00000262238.4
YY1 transcription factor
chr1_+_151171012 0.24 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr14_-_30396948 0.24 ENST00000331968.5
protein kinase D1
chr4_-_114900831 0.23 ENST00000315366.7
arylsulfatase family, member J
chr2_+_239335449 0.23 ENST00000264607.4
ankyrin repeat and SOCS box containing 1
chr14_-_77843390 0.23 ENST00000216468.7
transmembrane emp24 protein transport domain containing 8
chr17_+_12569306 0.23 ENST00000425538.1
myocardin
chr4_+_15004165 0.23 ENST00000538197.1
ENST00000541112.1
ENST00000442003.2
cytoplasmic polyadenylation element binding protein 2
chrX_+_154997474 0.23 ENST00000302805.2
sprouty homolog 3 (Drosophila)
chr14_-_89259080 0.22 ENST00000554922.1
ENST00000352093.5
echinoderm microtubule associated protein like 5
chr17_-_8066250 0.22 ENST00000488857.1
ENST00000481878.1
ENST00000316509.6
ENST00000498285.1
vesicle-associated membrane protein 2 (synaptobrevin 2)
Uncharacterized protein
chr7_-_82073109 0.22 ENST00000356860.3
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr7_+_28452130 0.22 ENST00000357727.2
cAMP responsive element binding protein 5
chr11_+_66025167 0.22 ENST00000394067.2
ENST00000316924.5
ENST00000421552.1
ENST00000394078.1
kinesin light chain 2
chr18_+_55018044 0.22 ENST00000324000.3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr2_+_203499901 0.21 ENST00000303116.6
ENST00000392238.2
family with sequence similarity 117, member B
chrX_-_18372792 0.21 ENST00000251900.4
sex comb on midleg-like 2 (Drosophila)
chr17_+_28705921 0.21 ENST00000225719.4
carboxypeptidase D
chr1_-_200379180 0.21 ENST00000294740.3
zinc finger protein 281
chr11_-_46722117 0.21 ENST00000311956.4
Rho GTPase activating protein 1
chr5_-_11904152 0.20 ENST00000304623.8
ENST00000458100.2
catenin (cadherin-associated protein), delta 2
chr17_-_62207485 0.20 ENST00000433197.3
endoplasmic reticulum to nucleus signaling 1
chr20_+_39765581 0.20 ENST00000244007.3
phospholipase C, gamma 1
chr16_+_30960375 0.20 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI calcium release-activated calcium modulator 3
chr10_+_125425871 0.20 ENST00000284674.1
G protein-coupled receptor 26
chr15_-_67546963 0.20 ENST00000561452.1
ENST00000261880.5
alpha- and gamma-adaptin binding protein
chr1_-_120612240 0.20 ENST00000256646.2
notch 2
chr18_-_60987220 0.20 ENST00000398117.1
B-cell CLL/lymphoma 2
chr18_-_18691739 0.20 ENST00000399799.2
Rho-associated, coiled-coil containing protein kinase 1
chr7_-_73133959 0.20 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
syntaxin 1A (brain)
chr4_-_6202291 0.19 ENST00000282924.5
janus kinase and microtubule interacting protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of GGCAGUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.6 2.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.5 1.4 GO:0071109 superior temporal gyrus development(GO:0071109)
0.4 1.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.4 0.4 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.3 1.7 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.3 0.9 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.3 1.7 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.2 1.6 GO:2000669 positive regulation of pinocytosis(GO:0048549) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.2 0.9 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 0.7 GO:0044209 AMP salvage(GO:0044209)
0.2 0.8 GO:0044805 late nucleophagy(GO:0044805)
0.2 0.6 GO:0009946 proximal/distal axis specification(GO:0009946) neuroblast differentiation(GO:0014016)
0.2 0.5 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 0.7 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 0.5 GO:2000974 atrioventricular node development(GO:0003162) mitral valve formation(GO:0003192) cardiac right atrium morphogenesis(GO:0003213) negative regulation of pro-B cell differentiation(GO:2000974)
0.2 1.1 GO:0097338 response to clozapine(GO:0097338)
0.2 0.2 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.2 0.6 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.6 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.7 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.4 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1 0.7 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 1.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.4 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.8 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 1.4 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.4 GO:0036309 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.1 0.4 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.4 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.4 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.3 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.9 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.6 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.1 0.4 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.3 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.5 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.3 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 1.2 GO:0007028 cytoplasm organization(GO:0007028)
0.1 0.3 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.3 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.8 GO:0015014 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.7 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.4 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.7 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 1.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 0.6 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222)
0.1 0.7 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 0.4 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.4 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.1 0.4 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.2 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.2 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.3 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.3 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.1 1.8 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.7 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 0.4 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.6 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.5 GO:0060613 fat pad development(GO:0060613)
0.0 0.2 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.2 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.8 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.5 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.5 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.9 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.8 GO:0009642 response to light intensity(GO:0009642)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.2 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.4 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.2 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.2 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
0.0 0.7 GO:0006907 pinocytosis(GO:0006907)
0.0 0.4 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 0.9 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.8 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0035912 dorsal aorta morphogenesis(GO:0035912)
0.0 1.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.4 GO:0035058 nonmotile primary cilium assembly(GO:0035058) regulation of nonmotile primary cilium assembly(GO:1902855) positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.0 GO:0072300 positive regulation of metanephric glomerulus development(GO:0072300)
0.0 0.4 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.0 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.6 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.2 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.7 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.7 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 1.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.4 GO:0007398 ectoderm development(GO:0007398)
0.0 0.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.3 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.0 0.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.0 GO:0072240 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990032 parallel fiber(GO:1990032)
0.2 0.9 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.6 GO:0097513 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.1 1.0 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 1.0 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 0.3 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.4 GO:0045298 tubulin complex(GO:0045298)
0.1 1.8 GO:0033643 host cell part(GO:0033643)
0.1 0.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.7 GO:0070695 FHF complex(GO:0070695)
0.1 1.4 GO:0033010 paranodal junction(GO:0033010)
0.1 1.1 GO:0016600 flotillin complex(GO:0016600)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.2 GO:0016938 kinesin I complex(GO:0016938)
0.1 0.2 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.1 0.2 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.5 GO:0005638 lamin filament(GO:0005638)
0.1 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.1 GO:0044308 axonal spine(GO:0044308)
0.1 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.6 GO:0005883 neurofilament(GO:0005883)
0.0 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 4.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 2.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0032059 bleb(GO:0032059)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.3 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 0.7 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 0.8 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 0.5 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.7 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.3 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 1.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.4 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.9 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.3 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.6 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.5 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.5 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.9 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.2 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.2 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.1 0.4 GO:0001515 opioid peptide activity(GO:0001515)
0.1 1.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.2 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 1.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.9 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.6 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.3 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.7 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 4.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 1.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.4 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 1.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 1.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.0 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 1.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.3 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.8 GO:0048365 Rac GTPase binding(GO:0048365)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 2.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.2 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 4.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.8 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 2.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors