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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for GLIS1

Z-value: 0.31

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Transcription factors associated with GLIS1

Gene Symbol Gene ID Gene Info
ENSG00000174332.3 GLIS family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS1hg19_v2_chr1_-_54199877_541998770.183.4e-01Click!

Activity profile of GLIS1 motif

Sorted Z-values of GLIS1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_80332153 0.61 ENST00000313135.2
urotensin 2 receptor
chr4_+_191008560 0.50 ENST00000554690.1
double homeobox 4 like 3
chr4_+_190992087 0.44 ENST00000553598.1
double homeobox 4 like 7
chr4_+_190995380 0.43 ENST00000555191.1
double homeobox 4 like 6
chr4_+_190998673 0.42 ENST00000554668.1
double homeobox 4 like 5
chr4_+_191005267 0.42 ENST00000556625.1
double homeobox 4
chr4_+_191011860 0.42 ENST00000440426.1
double homeobox 4 like 2
chr4_+_191001979 0.41 ENST00000538692.1
double homeobox 4 like 4
chr18_+_11751493 0.29 ENST00000269162.5
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr11_+_68671310 0.21 ENST00000255078.3
ENST00000539224.1
immunoglobulin mu binding protein 2
chr18_+_11752040 0.20 ENST00000423027.3
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr19_-_38397228 0.17 ENST00000447313.2
WD repeat domain 87
chr19_+_40697514 0.16 ENST00000253055.3
mitogen-activated protein kinase kinase kinase 10
chr19_-_42463418 0.16 ENST00000600292.1
ENST00000601078.1
ENST00000601891.1
ENST00000222008.6
Rab acceptor 1 (prenylated)
chr18_+_11751466 0.09 ENST00000535121.1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr11_-_68671264 0.07 ENST00000362034.2
mitochondrial ribosomal protein L21

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.4 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0032797 SMN complex(GO:0032797)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway