Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for GLIS2

Z-value: 0.69

Motif logo

logo of

Transcription factors associated with GLIS2

Gene Symbol Gene ID Gene Info
GLIS2
ENSG00000126603.4 GLIS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS2hg19_v2_chr16_+_4364762_4364762,
hg19_v2_chr16_+_4382225_4382225		-0.328.4e-02Click!

Activity profile of GLIS2 motif

Sorted Z-values of GLIS2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_2903514 3.17 ENST00000380698.4
SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr2_+_24272576 2.11 ENST00000380986.4
ENST00000452109.1
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr19_+_35645817 2.08 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr19_+_35645618 2.01 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5
FXYD domain containing ion transport regulator 5
chr1_-_186649543 1.82 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr2_+_24272543 1.82 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr1_-_153348067 1.36 ENST00000368737.3
S100A12
S100 calcium binding protein A12
chr1_-_28520447 1.31 ENST00000539896.1
PTAFR
platelet-activating factor receptor
chr7_-_73133959 1.27 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
STX1A
syntaxin 1A (brain)
chr11_+_844067 1.16 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
TSPAN4
tetraspanin 4
chr20_+_44637526 1.12 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr22_+_31489344 1.12 ENST00000404574.1
SMTN
smoothelin
chr19_+_45409011 1.10 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE
apolipoprotein E
chr2_+_37571717 1.10 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr12_+_57853918 1.05 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1
GLI family zinc finger 1
chr19_+_54372639 0.94 ENST00000391769.2
MYADM
myeloid-associated differentiation marker
chr1_-_40157345 0.94 ENST00000372844.3
HPCAL4
hippocalcin like 4
chr19_+_17858509 0.94 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1
FCH domain only 1
chr11_-_64646086 0.93 ENST00000320631.3
EHD1
EH-domain containing 1
chr6_-_39290316 0.90 ENST00000425054.2
ENST00000373227.4
ENST00000373229.5
ENST00000437525.2
KCNK16
potassium channel, subfamily K, member 16
chr19_+_45349432 0.88 ENST00000252485.4
PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr22_+_23264766 0.88 ENST00000390331.2
IGLC7
immunoglobulin lambda constant 7
chr8_+_27183033 0.86 ENST00000420218.2
PTK2B
protein tyrosine kinase 2 beta
chr17_-_76921459 0.83 ENST00000262768.7
TIMP2
TIMP metallopeptidase inhibitor 2
chr2_-_27718052 0.82 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr19_+_45418067 0.80 ENST00000589078.1
ENST00000586638.1
APOC1
apolipoprotein C-I
chr12_+_119616447 0.80 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr5_-_176836577 0.78 ENST00000253496.3
F12
coagulation factor XII (Hageman factor)
chr2_+_37571845 0.77 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr7_+_2671663 0.76 ENST00000407643.1
TTYH3
tweety family member 3
chr6_-_39290744 0.75 ENST00000507712.1
KCNK16
potassium channel, subfamily K, member 16
chr17_+_41476327 0.75 ENST00000320033.4
ARL4D
ADP-ribosylation factor-like 4D
chrX_-_153602991 0.74 ENST00000369850.3
ENST00000422373.1
FLNA
filamin A, alpha
chr1_-_24127256 0.73 ENST00000418277.1
GALE
UDP-galactose-4-epimerase
chr19_+_17858547 0.72 ENST00000600676.1
ENST00000600209.1
ENST00000596309.1
ENST00000598539.1
ENST00000597474.1
ENST00000593385.1
ENST00000598067.1
ENST00000593833.1
FCHO1
FCH domain only 1
chr13_-_20767037 0.69 ENST00000382848.4
GJB2
gap junction protein, beta 2, 26kDa
chr1_-_6550625 0.68 ENST00000377725.1
ENST00000340850.5
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr5_-_1524015 0.68 ENST00000283415.3
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr8_+_27182862 0.68 ENST00000521164.1
ENST00000346049.5
PTK2B
protein tyrosine kinase 2 beta
chr19_-_55652290 0.67 ENST00000589745.1
TNNT1
troponin T type 1 (skeletal, slow)
chr19_+_11200038 0.66 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
LDLR
low density lipoprotein receptor
chr16_+_70680439 0.63 ENST00000288098.2
IL34
interleukin 34
chr19_+_54369608 0.63 ENST00000336967.3
MYADM
myeloid-associated differentiation marker
chr2_+_114737472 0.62 ENST00000420161.1
AC110769.3
AC110769.3
chr1_-_156675535 0.62 ENST00000368221.1
CRABP2
cellular retinoic acid binding protein 2
chr7_+_77167343 0.60 ENST00000433369.2
ENST00000415482.2
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr22_-_28197486 0.60 ENST00000302326.4
MN1
meningioma (disrupted in balanced translocation) 1
chr8_+_38243951 0.60 ENST00000297720.5
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr22_-_30685596 0.59 ENST00000404953.3
ENST00000407689.3
GATSL3
GATS protein-like 3
chr21_-_31869451 0.59 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr13_+_110959598 0.58 ENST00000360467.5
COL4A2
collagen, type IV, alpha 2
chr19_+_48824711 0.57 ENST00000599704.1
EMP3
epithelial membrane protein 3
chr1_-_19229248 0.57 ENST00000375341.3
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr19_+_48828582 0.57 ENST00000270221.6
ENST00000596315.1
EMP3
epithelial membrane protein 3
chr19_-_41859814 0.56 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr19_-_42931567 0.55 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr19_+_45417504 0.55 ENST00000588750.1
ENST00000588802.1
APOC1
apolipoprotein C-I
chr19_-_46405861 0.55 ENST00000322217.5
MYPOP
Myb-related transcription factor, partner of profilin
chr19_-_45661995 0.54 ENST00000438936.2
NKPD1
NTPase, KAP family P-loop domain containing 1
chr16_-_32688053 0.54 ENST00000398682.4
TP53TG3
TP53 target 3
chr10_-_33623564 0.53 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr9_+_139847347 0.53 ENST00000371632.3
LCN12
lipocalin 12
chr22_-_21482046 0.52 ENST00000419447.1
POM121L7
POM121 transmembrane nucleoporin-like 7
chr21_+_34775698 0.52 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr16_+_27078219 0.51 ENST00000418886.1
C16orf82
chromosome 16 open reading frame 82
chr16_-_29910365 0.51 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr7_+_77167376 0.51 ENST00000435495.2
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr22_-_46931191 0.51 ENST00000454637.1
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1
chr1_-_156675368 0.50 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chr3_-_48130314 0.50 ENST00000439356.1
ENST00000395734.3
ENST00000426837.2
MAP4
microtubule-associated protein 4
chr14_+_94640633 0.50 ENST00000304338.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr22_-_21482352 0.50 ENST00000329949.3
POM121L7
POM121 transmembrane nucleoporin-like 7
chr11_-_2160180 0.50 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr22_-_50700140 0.49 ENST00000215659.8
MAPK12
mitogen-activated protein kinase 12
chr2_-_89310012 0.49 ENST00000493819.1
IGKV1-9
immunoglobulin kappa variable 1-9
chr20_-_23969416 0.49 ENST00000335694.4
GGTLC1
gamma-glutamyltransferase light chain 1
chr6_-_43484718 0.47 ENST00000372422.2
YIPF3
Yip1 domain family, member 3
chr2_+_102508955 0.47 ENST00000414004.2
FLJ20373
FLJ20373
chr16_+_3070313 0.47 ENST00000326577.4
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr1_+_148928291 0.46 ENST00000420597.1
ENST00000452399.1
ENST00000294715.2
ENST00000539543.1
RP11-14N7.2
RP11-14N7.2
chr19_+_45417921 0.46 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1
apolipoprotein C-I
chr16_+_32264040 0.46 ENST00000398664.3
TP53TG3D
TP53 target 3D
chr12_-_51785182 0.46 ENST00000356317.3
ENST00000603188.1
ENST00000604847.1
ENST00000604506.1
GALNT6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr10_-_75634219 0.45 ENST00000305762.7
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr3_+_111578131 0.44 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr22_+_18834324 0.44 ENST00000342005.4
AC008132.13
Uncharacterized protein
chr16_+_3070356 0.44 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr16_+_57279248 0.43 ENST00000562023.1
ENST00000563234.1
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr19_+_45417812 0.43 ENST00000592535.1
APOC1
apolipoprotein C-I
chr17_-_5138099 0.43 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chr11_-_64546202 0.43 ENST00000377390.3
ENST00000227503.9
ENST00000377394.3
ENST00000422298.2
ENST00000334944.5
SF1
splicing factor 1
chr7_+_116166331 0.42 ENST00000393468.1
ENST00000393467.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr17_+_7210898 0.42 ENST00000572815.1
EIF5A
eukaryotic translation initiation factor 5A
chr4_+_37828255 0.42 ENST00000381967.4
ENST00000544359.1
ENST00000537241.1
PGM2
phosphoglucomutase 2
chr5_+_169010638 0.42 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1
spindle apparatus coiled-coil protein 1
chr4_-_48082192 0.42 ENST00000507351.1
TXK
TXK tyrosine kinase
chr22_-_39640756 0.41 ENST00000331163.6
PDGFB
platelet-derived growth factor beta polypeptide
chr11_+_86748998 0.41 ENST00000525018.1
ENST00000355734.4
TMEM135
transmembrane protein 135
chrX_+_53078273 0.41 ENST00000332582.4
GPR173
G protein-coupled receptor 173
chr21_-_45671014 0.41 ENST00000436357.1
DNMT3L
DNA (cytosine-5-)-methyltransferase 3-like
chr1_-_228604328 0.40 ENST00000355586.4
ENST00000366698.2
ENST00000520264.1
ENST00000479800.1
ENST00000295033.3
TRIM17
tripartite motif containing 17
chr1_+_160051319 0.40 ENST00000368088.3
KCNJ9
potassium inwardly-rectifying channel, subfamily J, member 9
chr12_-_57941004 0.40 ENST00000550750.1
ENST00000548249.1
DCTN2
dynactin 2 (p50)
chr21_+_34775181 0.40 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr6_+_144164455 0.39 ENST00000367576.5
LTV1
LTV1 homolog (S. cerevisiae)
chr19_+_10131437 0.39 ENST00000587782.1
RDH8
retinol dehydrogenase 8 (all-trans)
chr3_-_48470838 0.39 ENST00000358459.4
ENST00000358536.4
PLXNB1
plexin B1
chr16_+_69458537 0.39 ENST00000515314.1
ENST00000561792.1
ENST00000568237.1
CYB5B
cytochrome b5 type B (outer mitochondrial membrane)
chr12_-_57940904 0.39 ENST00000550954.1
ENST00000434715.3
ENST00000546670.1
ENST00000543672.1
DCTN2
dynactin 2 (p50)
chr1_+_202431859 0.39 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr7_-_98741714 0.39 ENST00000361125.1
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr19_+_2249308 0.38 ENST00000592877.1
ENST00000221496.4
AMH
anti-Mullerian hormone
chr9_-_34637806 0.38 ENST00000477726.1
SIGMAR1
sigma non-opioid intracellular receptor 1
chr7_-_4998802 0.38 ENST00000406755.1
ENST00000404774.3
ENST00000401401.3
MMD2
monocyte to macrophage differentiation-associated 2
chr1_-_24126892 0.37 ENST00000374497.3
ENST00000425913.1
GALE
UDP-galactose-4-epimerase
chr10_+_106014468 0.37 ENST00000369710.4
ENST00000369713.5
ENST00000445155.1
GSTO1
glutathione S-transferase omega 1
chr17_+_28886584 0.37 ENST00000584297.1
ENST00000579181.1
TBC1D29
TBC1 domain family, member 29
chr1_-_1149506 0.37 ENST00000379236.3
TNFRSF4
tumor necrosis factor receptor superfamily, member 4
chr16_+_640201 0.37 ENST00000563109.1
RAB40C
RAB40C, member RAS oncogene family
chr20_-_30310797 0.37 ENST00000422920.1
BCL2L1
BCL2-like 1
chr8_+_38243967 0.36 ENST00000524874.1
ENST00000379957.4
ENST00000523983.2
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr15_-_79383102 0.36 ENST00000558480.2
ENST00000419573.3
RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr3_-_43663519 0.36 ENST00000427171.1
ENST00000292246.3
ANO10
anoctamin 10
chr12_-_53242770 0.36 ENST00000304620.4
ENST00000547110.1
KRT78
keratin 78
chr19_+_45147098 0.36 ENST00000425690.3
ENST00000344956.4
ENST00000403059.4
PVR
poliovirus receptor
chr11_-_627143 0.35 ENST00000176195.3
SCT
secretin
chr19_-_4517613 0.35 ENST00000301286.3
PLIN4
perilipin 4
chr6_-_163148780 0.35 ENST00000366892.1
ENST00000366898.1
ENST00000366897.1
ENST00000366896.1
PARK2
parkin RBR E3 ubiquitin protein ligase
chr18_-_59274139 0.35 ENST00000586949.1
RP11-879F14.2
RP11-879F14.2
chr1_-_201123546 0.34 ENST00000435310.1
ENST00000485839.2
ENST00000367330.1
TMEM9
transmembrane protein 9
chr20_+_35974532 0.34 ENST00000373578.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr14_-_54955721 0.33 ENST00000554908.1
GMFB
glia maturation factor, beta
chr11_+_63753883 0.33 ENST00000538426.1
ENST00000543004.1
OTUB1
OTU domain, ubiquitin aldehyde binding 1
chr19_+_7733929 0.33 ENST00000221515.2
RETN
resistin
chr12_+_57522258 0.33 ENST00000553277.1
ENST00000243077.3
LRP1
low density lipoprotein receptor-related protein 1
chr22_-_38794490 0.33 ENST00000400206.2
CSNK1E
casein kinase 1, epsilon
chr16_-_28518153 0.33 ENST00000356897.1
IL27
interleukin 27
chr21_+_34775772 0.33 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr20_-_30433396 0.33 ENST00000375978.3
FOXS1
forkhead box S1
chr1_-_201123586 0.33 ENST00000414605.2
ENST00000367334.5
ENST00000367332.1
TMEM9
transmembrane protein 9
chr16_+_33204980 0.32 ENST00000561509.1
TP53TG3C
TP53 target 3C
chr22_+_21400229 0.32 ENST00000342608.4
ENST00000543388.1
ENST00000442047.1
AC002472.13
Leucine-rich repeat-containing protein LOC400891
chr5_-_141060389 0.32 ENST00000504448.1
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr7_-_752577 0.32 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr19_+_45973120 0.32 ENST00000592811.1
ENST00000586615.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr11_-_71955210 0.32 ENST00000298231.5
PHOX2A
paired-like homeobox 2a
chr1_+_1950763 0.32 ENST00000378585.4
GABRD
gamma-aminobutyric acid (GABA) A receptor, delta
chr19_+_45582453 0.31 ENST00000591607.1
ENST00000591747.1
ENST00000270257.4
ENST00000391951.2
ENST00000587566.1
GEMIN7
MARK4
gem (nuclear organelle) associated protein 7
MAP/microtubule affinity-regulating kinase 4
chr15_+_42694573 0.31 ENST00000397200.4
ENST00000569827.1
CAPN3
calpain 3, (p94)
chr1_-_32110467 0.31 ENST00000440872.2
ENST00000373703.4
PEF1
penta-EF-hand domain containing 1
chr19_-_2050852 0.31 ENST00000541165.1
ENST00000591601.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr12_+_58166370 0.31 ENST00000300209.8
METTL21B
methyltransferase like 21B
chr1_-_31661000 0.31 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr19_-_49567124 0.31 ENST00000301411.3
NTF4
neurotrophin 4
chr9_-_35112376 0.31 ENST00000488109.2
FAM214B
family with sequence similarity 214, member B
chr19_+_11039391 0.30 ENST00000270502.6
C19orf52
chromosome 19 open reading frame 52
chr6_-_32908765 0.30 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr2_+_220492373 0.30 ENST00000317151.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr1_-_115300579 0.30 ENST00000358528.4
ENST00000525132.1
CSDE1
cold shock domain containing E1, RNA-binding
chr1_+_35544968 0.30 ENST00000359858.4
ENST00000373330.1
ZMYM1
zinc finger, MYM-type 1
chr17_-_7307358 0.30 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
TMEM256
TMEM256-PLSCR3
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr13_-_24007815 0.30 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr10_+_98064085 0.29 ENST00000419175.1
ENST00000371174.2
DNTT
DNA nucleotidylexotransferase
chr22_-_18257178 0.29 ENST00000342111.5
BID
BH3 interacting domain death agonist
chr1_-_209824643 0.29 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr14_-_36988882 0.29 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr9_+_103189536 0.28 ENST00000374885.1
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr11_-_72353451 0.28 ENST00000376450.3
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr14_+_100150622 0.28 ENST00000261835.3
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr14_-_107211459 0.28 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr19_+_41103063 0.28 ENST00000308370.7
LTBP4
latent transforming growth factor beta binding protein 4
chr1_-_43638168 0.27 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr19_+_14640372 0.27 ENST00000215567.5
ENST00000598298.1
ENST00000596073.1
ENST00000600083.1
ENST00000436007.2
TECR
trans-2,3-enoyl-CoA reductase
chr9_+_139839711 0.27 ENST00000224181.3
C8G
complement component 8, gamma polypeptide
chr21_-_45681765 0.26 ENST00000431166.1
DNMT3L
DNA (cytosine-5-)-methyltransferase 3-like
chr1_-_115300592 0.26 ENST00000261443.5
ENST00000534699.1
ENST00000339438.6
ENST00000529046.1
ENST00000525970.1
ENST00000369530.1
ENST00000530886.1
CSDE1
cold shock domain containing E1, RNA-binding
chr16_+_765092 0.26 ENST00000568223.2
METRN
meteorin, glial cell differentiation regulator
chr7_-_92107229 0.26 ENST00000603053.1
ERVW-1
endogenous retrovirus group W, member 1
chr19_+_56116771 0.26 ENST00000568956.1
ZNF865
zinc finger protein 865
chr16_+_84224780 0.26 ENST00000315906.5
ADAD2
adenosine deaminase domain containing 2
chr15_+_91478493 0.26 ENST00000418476.2
UNC45A
unc-45 homolog A (C. elegans)
chr8_-_87081926 0.26 ENST00000276616.2
PSKH2
protein serine kinase H2
chr19_+_17186577 0.25 ENST00000595618.1
ENST00000594824.1
MYO9B
myosin IXB
chrX_+_51927919 0.25 ENST00000416960.1
MAGED4
melanoma antigen family D, 4
chr20_+_52824367 0.25 ENST00000371419.2
PFDN4
prefoldin subunit 4
chr2_+_48757278 0.25 ENST00000404752.1
ENST00000406226.1
STON1
stonin 1
chr2_-_88285309 0.24 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chr2_-_85829496 0.24 ENST00000409668.1
TMEM150A
transmembrane protein 150A
chr1_+_87595497 0.23 ENST00000471417.1
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr16_+_84224740 0.23 ENST00000268624.3
ADAD2
adenosine deaminase domain containing 2
chr9_+_139839686 0.23 ENST00000371634.2
C8G
complement component 8, gamma polypeptide
chr19_-_38397228 0.23 ENST00000447313.2
WDR87
WD repeat domain 87
chr20_-_34638841 0.23 ENST00000565493.1
LINC00657
long intergenic non-protein coding RNA 657
chr13_+_47127322 0.22 ENST00000389798.3
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr9_-_34710066 0.22 ENST00000378792.1
ENST00000259607.2
CCL21
chemokine (C-C motif) ligand 21
chr6_+_43044003 0.22 ENST00000230419.4
ENST00000476760.1
ENST00000471863.1
ENST00000349241.2
ENST00000352931.2
ENST00000345201.2
PTK7
protein tyrosine kinase 7
chr1_+_87595433 0.22 ENST00000469312.2
ENST00000490006.2
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr5_-_180237445 0.22 ENST00000393340.3
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr19_-_3772209 0.22 ENST00000555978.1
ENST00000555633.1
RAX2
retina and anterior neural fold homeobox 2
chr13_-_46425865 0.22 ENST00000400405.2
SIAH3
siah E3 ubiquitin protein ligase family member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
1.1 3.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.7 2.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.6 1.9 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.6 2.2 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.4 1.3 GO:1904316 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.4 1.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.4 1.5 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.4 1.1 GO:2000646 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
0.4 3.9 GO:0098870 neuronal action potential propagation(GO:0019227) positive regulation of axon regeneration(GO:0048680) action potential propagation(GO:0098870)
0.3 1.3 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.3 0.8 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 1.0 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.2 0.7 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.2 1.1 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.2 0.6 GO:1900126 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.2 0.7 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.2 0.5 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.8 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.4 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.4 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.4 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 1.7 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.7 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 0.4 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.4 GO:0060455 negative regulation of gastric acid secretion(GO:0060455) positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.6 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.3 GO:0086098 angiotensin-activated signaling pathway involved in heart process(GO:0086098)
0.1 0.6 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.3 GO:2000196 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.1 1.5 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 0.3 GO:0021558 trochlear nerve development(GO:0021558)
0.1 0.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.4 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.9 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 1.5 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.3 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.6 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.7 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.2 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.2 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.2 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 1.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.2 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.3 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.2 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.2 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.1 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.5 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.1 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.3 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 0.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 1.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.3 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0 1.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 1.2 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.2 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.6 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.1 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.4 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.5 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.2 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.2 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.8 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.3 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.4 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.4 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787) regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.4 GO:0014733 regulation of skeletal muscle adaptation(GO:0014733)
0.0 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.3 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.7 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.1 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.0 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 1.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.4 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.0 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.0 0.3 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.4 GO:0032094 response to food(GO:0032094)
0.0 0.2 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.3 1.3 GO:0048787 presynaptic active zone membrane(GO:0048787) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 0.7 GO:0031523 Myb complex(GO:0031523)
0.2 0.7 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.2 0.8 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 1.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.0 GO:0042627 chylomicron(GO:0042627)
0.1 0.7 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 4.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.3 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.4 GO:0034448 EGO complex(GO:0034448)
0.1 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.8 GO:0005869 dynactin complex(GO:0005869)
0.1 0.7 GO:0097449 astrocyte projection(GO:0097449)
0.1 0.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 3.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 1.5 GO:0097546 ciliary base(GO:0097546)
0.0 2.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 1.4 GO:0002102 podosome(GO:0002102)
0.0 1.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.6 GO:0005901 caveola(GO:0005901)
0.0 1.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 1.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.9 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.6 1.9 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.5 1.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.5 1.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 3.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 0.9 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.3 1.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.3 1.3 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.3 1.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.2 0.6 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.2 0.7 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.4 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 1.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 1.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.2 GO:0031403 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.1 1.6 GO:0019841 retinol binding(GO:0019841)
0.1 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.1 3.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.3 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 1.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.4 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1 0.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 3.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.1 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.5 GO:0031014 troponin T binding(GO:0031014)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.1 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.2 GO:0070290 phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 1.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.1 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 1.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 4.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 2.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs