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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for GSC_GSC2

Z-value: 0.86

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Transcription factors associated with GSC_GSC2

Gene Symbol Gene ID Gene Info
GSC
ENSG00000133937.3 goosecoid homeobox
GSC2
ENSG00000063515.2 goosecoid homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GSC2hg19_v2_chr22_-_19137796_191377960.261.6e-01Click!
GSChg19_v2_chr14_-_95236551_952365760.019.7e-01Click!

Activity profile of GSC_GSC2 motif

Sorted Z-values of GSC_GSC2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_4689649 10.82 ENST00000441199.2
ENST00000416307.2
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr4_-_16077741 8.54 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
PROM1
prominin 1
chr17_-_4689727 7.77 ENST00000328739.5
ENST00000354194.4
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr1_+_151682909 5.08 ENST00000326413.3
ENST00000442233.2
RIIAD1
AL589765.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr3_+_111393659 3.23 ENST00000477665.1
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr1_+_162351503 2.98 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr15_-_27184664 2.37 ENST00000541819.2
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr3_-_65583561 2.33 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr3_-_19975665 2.30 ENST00000295824.9
ENST00000389256.4
EFHB
EF-hand domain family, member B
chr13_+_36050881 2.14 ENST00000537702.1
NBEA
neurobeachin
chr2_-_175711133 1.84 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr5_+_76114758 1.69 ENST00000514165.1
ENST00000296677.4
F2RL1
coagulation factor II (thrombin) receptor-like 1
chr5_+_50678921 1.62 ENST00000230658.7
ISL1
ISL LIM homeobox 1
chr10_+_104178946 1.60 ENST00000432590.1
FBXL15
F-box and leucine-rich repeat protein 15
chr8_-_133123406 1.32 ENST00000434736.2
HHLA1
HERV-H LTR-associating 1
chr1_+_244214577 1.31 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr22_-_19137796 1.29 ENST00000086933.2
GSC2
goosecoid homeobox 2
chr5_+_133451254 1.23 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr17_+_68100989 1.20 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr11_+_61522844 1.11 ENST00000265460.5
MYRF
myelin regulatory factor
chr10_-_104178857 1.10 ENST00000020673.5
PSD
pleckstrin and Sec7 domain containing
chr7_-_120497178 1.04 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12
tetraspanin 12
chr17_+_4643300 1.02 ENST00000433935.1
ZMYND15
zinc finger, MYND-type containing 15
chr17_+_4643337 1.00 ENST00000592813.1
ZMYND15
zinc finger, MYND-type containing 15
chr3_-_54962100 0.99 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr17_-_4643114 0.98 ENST00000293778.6
CXCL16
chemokine (C-X-C motif) ligand 16
chr9_+_2015335 0.95 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr13_-_95131923 0.89 ENST00000377028.5
ENST00000446125.1
DCT
dopachrome tautomerase
chr7_-_128415844 0.89 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chrX_-_10588459 0.88 ENST00000380782.2
MID1
midline 1 (Opitz/BBB syndrome)
chr11_-_76155700 0.87 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr11_-_76155618 0.86 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr12_-_13248598 0.84 ENST00000337630.6
ENST00000545699.1
GSG1
germ cell associated 1
chrX_-_10588595 0.83 ENST00000423614.1
ENST00000317552.4
MID1
midline 1 (Opitz/BBB syndrome)
chr2_-_29297127 0.82 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr17_-_40264692 0.80 ENST00000591220.1
ENST00000251642.3
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr17_-_14683517 0.76 ENST00000379640.1
AC005863.1
AC005863.1
chr7_+_116660246 0.76 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr13_+_73632897 0.75 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr1_+_169079823 0.72 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr19_+_2476116 0.71 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr14_-_101034407 0.70 ENST00000443071.2
ENST00000557378.1
BEGAIN
brain-enriched guanylate kinase-associated
chr20_+_59654146 0.69 ENST00000441660.1
RP5-827L5.1
RP5-827L5.1
chr1_-_26633067 0.67 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBXN11
UBX domain protein 11
chr3_-_193272874 0.63 ENST00000342695.4
ATP13A4
ATPase type 13A4
chr4_+_170541660 0.63 ENST00000513761.1
ENST00000347613.4
CLCN3
chloride channel, voltage-sensitive 3
chr15_+_44092784 0.61 ENST00000458412.1
HYPK
huntingtin interacting protein K
chr1_+_17248418 0.61 ENST00000375541.5
CROCC
ciliary rootlet coiled-coil, rootletin
chrX_-_6146876 0.59 ENST00000381095.3
NLGN4X
neuroligin 4, X-linked
chr3_-_193272741 0.59 ENST00000392443.3
ATP13A4
ATPase type 13A4
chr4_+_170541835 0.59 ENST00000504131.2
CLCN3
chloride channel, voltage-sensitive 3
chr10_-_126716459 0.59 ENST00000309035.6
CTBP2
C-terminal binding protein 2
chr17_-_9808887 0.56 ENST00000226193.5
RCVRN
recoverin
chr7_+_138482695 0.55 ENST00000422794.2
ENST00000397602.3
ENST00000442682.2
ENST00000458494.1
ENST00000413208.1
TMEM213
transmembrane protein 213
chr16_-_31076332 0.55 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668
zinc finger protein 668
chr5_+_173316341 0.51 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr19_-_48547294 0.49 ENST00000293255.2
CABP5
calcium binding protein 5
chr3_-_193096600 0.46 ENST00000446087.1
ENST00000342358.4
ATP13A5
ATPase type 13A5
chr19_-_55866061 0.46 ENST00000588572.2
ENST00000593184.1
ENST00000589467.1
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr17_+_73521763 0.46 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr11_-_130184555 0.45 ENST00000525842.1
ZBTB44
zinc finger and BTB domain containing 44
chr17_+_44668035 0.45 ENST00000398238.4
ENST00000225282.8
NSF
N-ethylmaleimide-sensitive factor
chr10_+_102222798 0.45 ENST00000343737.5
WNT8B
wingless-type MMTV integration site family, member 8B
chr14_-_67981870 0.44 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr2_+_189156721 0.44 ENST00000409927.1
ENST00000409805.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr1_+_156117149 0.43 ENST00000435124.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr19_-_49843539 0.43 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4
CTC-301O7.4
chr16_-_31076273 0.42 ENST00000426488.2
ZNF668
zinc finger protein 668
chr1_+_40839369 0.41 ENST00000372718.3
SMAP2
small ArfGAP2
chrM_+_9207 0.41 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr2_+_189156586 0.41 ENST00000409830.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr5_-_149324306 0.40 ENST00000255266.5
PDE6A
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr19_-_49520338 0.39 ENST00000221421.2
LHB
luteinizing hormone beta polypeptide
chr7_-_138482849 0.39 ENST00000353492.4
ATP6V0A4
ATPase, H+ transporting, lysosomal V0 subunit a4
chr4_+_70894130 0.36 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr11_-_128712362 0.36 ENST00000392664.2
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr15_-_43559055 0.36 ENST00000220420.5
ENST00000349114.4
TGM5
transglutaminase 5
chr10_-_49482907 0.36 ENST00000374201.3
ENST00000407470.4
FRMPD2
FERM and PDZ domain containing 2
chr2_+_189156389 0.35 ENST00000409843.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr22_-_29663954 0.35 ENST00000216085.7
RHBDD3
rhomboid domain containing 3
chr5_+_38258511 0.34 ENST00000354891.3
ENST00000322350.5
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr12_+_104680659 0.33 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
TXNRD1
thioredoxin reductase 1
chr1_+_202431859 0.33 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr12_+_7053228 0.32 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr4_+_159727272 0.32 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr17_-_48207157 0.31 ENST00000330175.4
ENST00000503131.1
SAMD14
sterile alpha motif domain containing 14
chr17_+_48911942 0.31 ENST00000426127.1
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr4_+_170541678 0.30 ENST00000360642.3
ENST00000512813.1
CLCN3
chloride channel, voltage-sensitive 3
chr5_-_150138061 0.30 ENST00000521533.1
ENST00000424236.1
DCTN4
dynactin 4 (p62)
chr12_+_7053172 0.30 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr14_-_67981916 0.30 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr17_-_19651668 0.30 ENST00000494157.2
ENST00000225740.6
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr7_-_138482933 0.30 ENST00000310018.2
ATP6V0A4
ATPase, H+ transporting, lysosomal V0 subunit a4
chr16_-_68269971 0.29 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr17_-_19651654 0.28 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr12_-_2027639 0.28 ENST00000586184.1
ENST00000587995.1
ENST00000585732.1
CACNA2D4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr11_+_44587141 0.27 ENST00000227155.4
ENST00000342935.3
ENST00000532544.1
CD82
CD82 molecule
chrX_-_21676442 0.27 ENST00000379499.2
KLHL34
kelch-like family member 34
chr12_-_55375622 0.27 ENST00000316577.8
TESPA1
thymocyte expressed, positive selection associated 1
chr10_-_89577910 0.24 ENST00000308448.7
ENST00000541004.1
ATAD1
ATPase family, AAA domain containing 1
chr10_-_126849588 0.23 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chr14_+_52327350 0.23 ENST00000555472.1
ENST00000556766.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr1_-_165414414 0.23 ENST00000359842.5
RXRG
retinoid X receptor, gamma
chr3_-_49058479 0.23 ENST00000440857.1
DALRD3
DALR anticodon binding domain containing 3
chr5_+_139781445 0.22 ENST00000532219.1
ENST00000394722.3
ANKHD1-EIF4EBP3
ANKHD1
ANKHD1-EIF4EBP3 readthrough
ankyrin repeat and KH domain containing 1
chrX_+_65382381 0.22 ENST00000519389.1
HEPH
hephaestin
chr9_+_17135016 0.22 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN
centlein, centrosomal protein
chr20_-_18774614 0.22 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chr17_-_4806369 0.21 ENST00000293780.4
CHRNE
cholinergic receptor, nicotinic, epsilon (muscle)
chr11_-_96076334 0.21 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr1_+_18957500 0.20 ENST00000375375.3
PAX7
paired box 7
chr13_+_114321463 0.20 ENST00000335678.6
GRK1
G protein-coupled receptor kinase 1
chr10_-_94003003 0.20 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr19_+_48325097 0.19 ENST00000221996.7
ENST00000539067.1
CRX
cone-rod homeobox
chr17_+_77020146 0.19 ENST00000579760.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr15_+_96876340 0.19 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr17_+_77020224 0.19 ENST00000339142.2
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_+_77020325 0.18 ENST00000311661.4
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr11_-_111794446 0.17 ENST00000527950.1
CRYAB
crystallin, alpha B
chrX_-_49089771 0.17 ENST00000376251.1
ENST00000323022.5
ENST00000376265.2
CACNA1F
calcium channel, voltage-dependent, L type, alpha 1F subunit
chr14_-_24551137 0.16 ENST00000396995.1
NRL
neural retina leucine zipper
chr14_-_24551195 0.16 ENST00000560550.1
NRL
neural retina leucine zipper
chrX_-_138724677 0.16 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2
MCF.2 cell line derived transforming sequence
chr22_+_29664305 0.15 ENST00000414183.2
ENST00000333395.6
ENST00000455726.1
ENST00000332035.6
EWSR1
EWS RNA-binding protein 1
chr2_-_152146385 0.15 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr7_+_73868220 0.15 ENST00000455841.2
GTF2IRD1
GTF2I repeat domain containing 1
chr11_-_62752429 0.15 ENST00000377871.3
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr1_+_180897269 0.15 ENST00000367587.1
KIAA1614
KIAA1614
chr7_-_155326532 0.14 ENST00000406197.1
ENST00000321736.5
CNPY1
canopy FGF signaling regulator 1
chr5_-_33984786 0.14 ENST00000296589.4
SLC45A2
solute carrier family 45, member 2
chrX_-_48931648 0.14 ENST00000376386.3
ENST00000376390.4
PRAF2
PRA1 domain family, member 2
chr4_+_103423055 0.14 ENST00000505458.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr5_+_139781393 0.14 ENST00000360839.2
ENST00000297183.6
ENST00000421134.1
ENST00000394723.3
ENST00000511151.1
ANKHD1
ankyrin repeat and KH domain containing 1
chrX_-_124097620 0.14 ENST00000371130.3
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr16_-_29874462 0.13 ENST00000566113.1
ENST00000569956.1
ENST00000570016.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr10_+_118350468 0.13 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1
pancreatic lipase-related protein 1
chr6_+_111580508 0.12 ENST00000368847.4
KIAA1919
KIAA1919
chr11_-_62752455 0.12 ENST00000360421.4
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr12_+_53818855 0.12 ENST00000550839.1
AMHR2
anti-Mullerian hormone receptor, type II
chr22_+_29664248 0.12 ENST00000406548.1
ENST00000437155.2
ENST00000415761.1
ENST00000331029.7
EWSR1
EWS RNA-binding protein 1
chr1_-_160313025 0.11 ENST00000368069.3
ENST00000241704.7
COPA
coatomer protein complex, subunit alpha
chr16_-_69373396 0.11 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chr11_-_119217365 0.11 ENST00000360167.4
ENST00000555262.1
ENST00000449574.2
ENST00000445041.2
MFRP
C1QTNF5
membrane frizzled-related protein
C1q and tumor necrosis factor related protein 5
chrX_-_110655306 0.10 ENST00000371993.2
DCX
doublecortin
chr15_+_58430368 0.10 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr7_-_104909435 0.09 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr11_-_47198380 0.09 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chrM_+_8527 0.08 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chr8_-_37457350 0.08 ENST00000519691.1
RP11-150O12.3
RP11-150O12.3
chrX_+_65382433 0.08 ENST00000374727.3
HEPH
hephaestin
chr14_-_21737610 0.08 ENST00000320084.7
ENST00000449098.1
ENST00000336053.6
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr5_-_146461027 0.08 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr14_-_21737551 0.08 ENST00000554891.1
ENST00000555883.1
ENST00000553753.1
ENST00000555914.1
ENST00000557336.1
ENST00000555215.1
ENST00000556628.1
ENST00000555137.1
ENST00000556226.1
ENST00000555309.1
ENST00000556142.1
ENST00000554969.1
ENST00000554455.1
ENST00000556513.1
ENST00000557201.1
ENST00000420743.2
ENST00000557768.1
ENST00000553300.1
ENST00000554383.1
ENST00000554539.1
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chrX_+_100878079 0.08 ENST00000471229.2
ARMCX3
armadillo repeat containing, X-linked 3
chr1_-_36615065 0.08 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3
trafficking protein particle complex 3
chr11_-_111783595 0.07 ENST00000528628.1
CRYAB
crystallin, alpha B
chr15_+_58430567 0.07 ENST00000536493.1
AQP9
aquaporin 9
chr10_+_18240834 0.07 ENST00000377371.3
ENST00000539911.1
SLC39A12
solute carrier family 39 (zinc transporter), member 12
chr20_-_39995467 0.07 ENST00000332312.3
EMILIN3
elastin microfibril interfacer 3
chr11_-_67290867 0.07 ENST00000353903.5
ENST00000294288.4
CABP2
calcium binding protein 2
chr8_-_116681221 0.07 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr2_+_189156638 0.06 ENST00000410051.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr2_-_30144432 0.06 ENST00000389048.3
ALK
anaplastic lymphoma receptor tyrosine kinase
chr7_+_73868120 0.06 ENST00000265755.3
GTF2IRD1
GTF2I repeat domain containing 1
chr6_-_29399744 0.06 ENST00000377154.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr5_+_140868717 0.06 ENST00000252087.1
PCDHGC5
protocadherin gamma subfamily C, 5
chr6_-_42690312 0.06 ENST00000230381.5
PRPH2
peripherin 2 (retinal degeneration, slow)
chr10_-_74714533 0.06 ENST00000373032.3
PLA2G12B
phospholipase A2, group XIIB
chr3_-_10547192 0.05 ENST00000360273.2
ENST00000343816.4
ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chrX_+_100333709 0.05 ENST00000372930.4
TMEM35
transmembrane protein 35
chr1_-_21606013 0.05 ENST00000357071.4
ECE1
endothelin converting enzyme 1
chr8_+_65285851 0.05 ENST00000520799.1
ENST00000521441.1
LINC00966
long intergenic non-protein coding RNA 966
chr10_+_18240814 0.04 ENST00000377374.4
SLC39A12
solute carrier family 39 (zinc transporter), member 12
chrX_-_138724994 0.04 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chrX_+_100646190 0.04 ENST00000471855.1
RPL36A
ribosomal protein L36a
chr16_+_4421841 0.03 ENST00000304735.3
VASN
vasorin
chrX_-_110655391 0.03 ENST00000356915.2
ENST00000356220.3
DCX
doublecortin
chr19_+_40877583 0.03 ENST00000596470.1
PLD3
phospholipase D family, member 3
chr14_+_52327109 0.03 ENST00000335281.4
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr10_-_27149904 0.02 ENST00000376166.1
ENST00000376138.3
ENST00000355394.4
ENST00000346832.5
ENST00000376134.3
ENST00000376137.4
ENST00000536334.1
ENST00000490841.2
ABI1
abl-interactor 1
chr15_+_48498480 0.02 ENST00000380993.3
ENST00000396577.3
SLC12A1
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr16_-_58004992 0.02 ENST00000564448.1
ENST00000251102.8
ENST00000311183.4
CNGB1
cyclic nucleotide gated channel beta 1
chr17_-_40021656 0.02 ENST00000319121.3
KLHL11
kelch-like family member 11
chr4_-_76823681 0.02 ENST00000286719.7
PPEF2
protein phosphatase, EF-hand calcium binding domain 2
chr16_+_81272287 0.01 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr9_+_4839762 0.01 ENST00000448872.2
ENST00000441844.1
RCL1
RNA terminal phosphate cyclase-like 1
chr1_-_11918988 0.01 ENST00000376468.3
NPPB
natriuretic peptide B
chr10_+_18240753 0.01 ENST00000377369.2
SLC39A12
solute carrier family 39 (zinc transporter), member 12
chr11_-_62783276 0.01 ENST00000535878.1
ENST00000545207.1
SLC22A8
solute carrier family 22 (organic anion transporter), member 8
chr14_-_106967788 0.01 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chrX_+_139791917 0.01 ENST00000607004.1
ENST00000370535.3
LINC00632
long intergenic non-protein coding RNA 632

Network of associatons between targets according to the STRING database.

First level regulatory network of GSC_GSC2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.5 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.6 1.7 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.5 1.6 GO:0048936 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913)
0.3 1.5 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 1.2 GO:0048619 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.2 0.8 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 0.6 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.1 0.4 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.7 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 0.9 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.1 2.0 GO:0071420 cellular response to histamine(GO:0071420)
0.1 1.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.6 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.7 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.6 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.8 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.6 GO:0003360 brainstem development(GO:0003360)
0.1 0.7 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.2 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 1.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 1.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 1.0 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.6 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.4 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.4 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 1.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 1.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.0 0.2 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.1 GO:0097254 renal tubular secretion(GO:0097254)
0.0 0.7 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 1.0 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 3.0 GO:0007286 spermatid development(GO:0007286)
0.0 0.4 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.3 GO:0061337 cardiac conduction(GO:0061337)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.3 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.0 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.2 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.7 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.5 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.8 GO:0097470 ribbon synapse(GO:0097470)
0.1 1.7 GO:0031143 pseudopodium(GO:0031143)
0.1 2.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.0 GO:0071564 npBAF complex(GO:0071564)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.9 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.0 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 1.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 1.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 2.0 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.9 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 9.7 GO:0042805 actinin binding(GO:0042805)
0.1 0.8 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.6 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.3 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 0.6 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 1.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 0.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 1.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.0 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.7 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 2.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.9 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.8 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.2 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.6 GO:0019894 kinesin binding(GO:0019894)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 2.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.2 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 0.9 REACTOME OPSINS Genes involved in Opsins
0.1 2.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport