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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for GUAAACA

Z-value: 1.11

Motif logo

logo of

miRNA associated with seed GUAAACA

NamemiRBASE accession
hsa-miR-30a-5p
MIMAT0000087
hsa-miR-30b-5p
MIMAT0000420
hsa-miR-30c-5p
MIMAT0000244
hsa-miR-30d-5p
MIMAT0000245
hsa-miR-30e-5p
MIMAT0000692

Activity profile of GUAAACA motif

Sorted Z-values of GUAAACA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_86159821 2.64 ENST00000369651.3
NT5E
5'-nucleotidase, ecto (CD73)
chr7_+_100770328 1.98 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr4_-_139163491 1.96 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr10_+_17271266 1.85 ENST00000224237.5
VIM
vimentin
chr7_-_41742697 1.75 ENST00000242208.4
INHBA
inhibin, beta A
chr6_-_30654977 1.73 ENST00000399199.3
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr11_-_115375107 1.69 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr22_+_30792846 1.65 ENST00000312932.9
ENST00000428195.1
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr2_+_95691417 1.57 ENST00000309988.4
MAL
mal, T-cell differentiation protein
chr8_+_26435359 1.54 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr11_-_87908600 1.44 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38
RAB38, member RAS oncogene family
chr7_-_143059845 1.33 ENST00000443739.2
FAM131B
family with sequence similarity 131, member B
chr7_-_83824169 1.28 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_-_9189229 1.23 ENST00000377411.4
GPR157
G protein-coupled receptor 157
chr5_-_157002775 1.18 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr7_+_87505544 1.15 ENST00000265728.1
DBF4
DBF4 homolog (S. cerevisiae)
chr15_-_83953466 1.14 ENST00000345382.2
BNC1
basonuclin 1
chr22_+_33197683 1.14 ENST00000266085.6
TIMP3
TIMP metallopeptidase inhibitor 3
chr17_+_70117153 1.13 ENST00000245479.2
SOX9
SRY (sex determining region Y)-box 9
chr12_-_85306594 1.11 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr15_-_34628951 1.09 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr5_+_86564739 1.08 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr1_-_20812690 1.07 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr17_+_42634844 1.07 ENST00000315323.3
FZD2
frizzled family receptor 2
chr9_-_72287191 1.02 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr5_-_134369973 1.01 ENST00000265340.7
PITX1
paired-like homeodomain 1
chr1_-_143913143 1.00 ENST00000400889.1
FAM72D
family with sequence similarity 72, member D
chr1_+_120839005 0.99 ENST00000369390.3
ENST00000452190.1
FAM72B
family with sequence similarity 72, member B
chr5_+_14143728 0.99 ENST00000344204.4
ENST00000537187.1
TRIO
trio Rho guanine nucleotide exchange factor
chr2_+_48541776 0.99 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chr2_+_102508955 0.98 ENST00000414004.2
FLJ20373
FLJ20373
chr11_+_94501497 0.98 ENST00000317829.8
ENST00000317837.9
ENST00000433060.2
AMOTL1
angiomotin like 1
chr6_+_118228657 0.97 ENST00000360388.4
SLC35F1
solute carrier family 35, member F1
chr2_-_235405679 0.95 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr19_+_926000 0.95 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr15_-_56209306 0.95 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr5_-_72744336 0.93 ENST00000499003.3
FOXD1
forkhead box D1
chr8_+_92082424 0.91 ENST00000285420.4
ENST00000404789.3
OTUD6B
OTU domain containing 6B
chr6_+_106546808 0.91 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr21_-_16437255 0.89 ENST00000400199.1
ENST00000400202.1
NRIP1
nuclear receptor interacting protein 1
chr22_-_37823468 0.89 ENST00000402918.2
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr5_+_172068232 0.88 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr2_-_26205340 0.87 ENST00000264712.3
KIF3C
kinesin family member 3C
chr6_-_40555176 0.87 ENST00000338305.6
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr20_+_42295745 0.87 ENST00000396863.4
ENST00000217026.4
MYBL2
v-myb avian myeloblastosis viral oncogene homolog-like 2
chr14_-_45431091 0.83 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28
kelch-like family member 28
chr11_+_63580855 0.82 ENST00000294244.4
C11orf84
chromosome 11 open reading frame 84
chr20_-_5591626 0.82 ENST00000379019.4
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr16_-_30022293 0.80 ENST00000565273.1
ENST00000567332.2
ENST00000350119.4
DOC2A
double C2-like domains, alpha
chr18_+_19749386 0.79 ENST00000269216.3
GATA6
GATA binding protein 6
chr3_-_98312548 0.79 ENST00000264193.2
CPOX
coproporphyrinogen oxidase
chr10_+_78078088 0.78 ENST00000496424.2
C10orf11
chromosome 10 open reading frame 11
chr17_-_76356148 0.78 ENST00000587578.1
ENST00000330871.2
SOCS3
suppressor of cytokine signaling 3
chr20_-_52790512 0.78 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr9_+_103204553 0.78 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr22_-_39096661 0.78 ENST00000216039.5
JOSD1
Josephin domain containing 1
chr17_-_33448468 0.77 ENST00000591723.1
ENST00000593039.1
ENST00000587405.1
RAD51L3-RFFL
RAD51D
Uncharacterized protein
RAD51 paralog D
chr13_-_61989655 0.77 ENST00000409204.4
PCDH20
protocadherin 20
chr8_-_95908902 0.77 ENST00000520509.1
CCNE2
cyclin E2
chr3_+_182971018 0.76 ENST00000326505.3
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr7_-_106301405 0.76 ENST00000523505.1
CCDC71L
coiled-coil domain containing 71-like
chr20_-_60982330 0.75 ENST00000279101.5
CABLES2
Cdk5 and Abl enzyme substrate 2
chr10_-_116164239 0.75 ENST00000419268.1
ENST00000304129.4
ENST00000545353.1
AFAP1L2
actin filament associated protein 1-like 2
chr16_-_84651673 0.74 ENST00000262428.4
COTL1
coactosin-like 1 (Dictyostelium)
chr8_-_141645645 0.73 ENST00000519980.1
ENST00000220592.5
AGO2
argonaute RISC catalytic component 2
chr16_+_2039946 0.72 ENST00000248121.2
ENST00000568896.1
SYNGR3
synaptogyrin 3
chr10_+_120967072 0.72 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr9_+_103235365 0.71 ENST00000374879.4
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr1_+_204042723 0.70 ENST00000367204.1
SOX13
SRY (sex determining region Y)-box 13
chr8_-_66754172 0.70 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr7_-_112579869 0.70 ENST00000297145.4
C7orf60
chromosome 7 open reading frame 60
chr20_+_306221 0.69 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr6_-_45345597 0.68 ENST00000371460.1
ENST00000371459.1
SUPT3H
suppressor of Ty 3 homolog (S. cerevisiae)
chr6_+_146864829 0.67 ENST00000367495.3
RAB32
RAB32, member RAS oncogene family
chr15_-_52821247 0.67 ENST00000399231.3
ENST00000399233.2
MYO5A
myosin VA (heavy chain 12, myoxin)
chr8_-_124553437 0.65 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr22_+_40390930 0.65 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr6_-_42419649 0.64 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1
transcriptional regulating factor 1
chr1_+_70876891 0.63 ENST00000411986.2
CTH
cystathionase (cystathionine gamma-lyase)
chr12_+_104359576 0.62 ENST00000392872.3
ENST00000436021.2
TDG
thymine-DNA glycosylase
chr22_+_21271714 0.62 ENST00000354336.3
CRKL
v-crk avian sarcoma virus CT10 oncogene homolog-like
chrX_+_117480036 0.61 ENST00000371822.5
ENST00000254029.3
ENST00000371825.3
WDR44
WD repeat domain 44
chr6_-_108395907 0.61 ENST00000193322.3
OSTM1
osteopetrosis associated transmembrane protein 1
chrX_-_15353629 0.61 ENST00000333590.4
ENST00000428964.1
ENST00000542278.1
PIGA
phosphatidylinositol glycan anchor biosynthesis, class A
chr2_-_204400113 0.60 ENST00000319170.5
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr1_-_208417620 0.60 ENST00000367033.3
PLXNA2
plexin A2
chr1_+_117452669 0.60 ENST00000393203.2
PTGFRN
prostaglandin F2 receptor inhibitor
chr10_+_76871454 0.59 ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr18_-_29264669 0.59 ENST00000306851.5
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr14_-_69446034 0.59 ENST00000193403.6
ACTN1
actinin, alpha 1
chr2_-_166651191 0.58 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr5_-_159739532 0.58 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL
cyclin J-like
chr7_-_27135591 0.58 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr1_-_179198702 0.58 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr2_+_136289030 0.58 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3HDM1
R3H domain containing 1
chr14_-_35182994 0.58 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr6_-_33714752 0.57 ENST00000451316.1
IP6K3
inositol hexakisphosphate kinase 3
chr14_+_55034599 0.56 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr10_-_105615164 0.56 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chr17_-_41174424 0.56 ENST00000355653.3
VAT1
vesicle amine transport 1
chr5_+_52285144 0.55 ENST00000296585.5
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr2_-_230933709 0.54 ENST00000436869.1
ENST00000295190.4
SLC16A14
solute carrier family 16, member 14
chr1_-_85156216 0.54 ENST00000342203.3
ENST00000370612.4
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr19_+_16187085 0.54 ENST00000300933.4
TPM4
tropomyosin 4
chr4_+_177241094 0.54 ENST00000503362.1
SPCS3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr12_-_113909877 0.54 ENST00000261731.3
LHX5
LIM homeobox 5
chr3_-_27498235 0.53 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr19_-_344786 0.53 ENST00000264819.4
MIER2
mesoderm induction early response 1, family member 2
chr13_-_73301819 0.52 ENST00000377818.3
MZT1
mitotic spindle organizing protein 1
chr6_+_15246501 0.52 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr2_+_153574428 0.51 ENST00000326446.5
ARL6IP6
ADP-ribosylation-like factor 6 interacting protein 6
chr18_-_12702769 0.51 ENST00000262127.2
CEP76
centrosomal protein 76kDa
chr10_-_33623564 0.50 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr2_+_28615669 0.50 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr1_+_90098606 0.50 ENST00000370454.4
LRRC8C
leucine rich repeat containing 8 family, member C
chr14_+_103851712 0.50 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3
MAP/microtubule affinity-regulating kinase 3
chr8_-_82754427 0.50 ENST00000353788.4
ENST00000520618.1
ENST00000518183.1
ENST00000396330.2
ENST00000519119.1
ENST00000345957.4
SNX16
sorting nexin 16
chr7_+_18535346 0.49 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9
histone deacetylase 9
chr3_+_141205852 0.49 ENST00000286364.3
ENST00000452898.1
RASA2
RAS p21 protein activator 2
chr6_-_53213780 0.49 ENST00000304434.6
ENST00000370918.4
ELOVL5
ELOVL fatty acid elongase 5
chr21_+_30671189 0.49 ENST00000286800.3
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr6_+_45389893 0.49 ENST00000371432.3
RUNX2
runt-related transcription factor 2
chr17_-_53499310 0.49 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr5_+_34656331 0.49 ENST00000265109.3
RAI14
retinoic acid induced 14
chr2_-_166930131 0.48 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr8_+_58907104 0.48 ENST00000361488.3
FAM110B
family with sequence similarity 110, member B
chr12_+_57916466 0.48 ENST00000355673.3
MBD6
methyl-CpG binding domain protein 6
chr17_-_76870222 0.48 ENST00000585421.1
TIMP2
TIMP metallopeptidase inhibitor 2
chr16_+_46918235 0.48 ENST00000340124.4
GPT2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr5_+_36152163 0.48 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr15_-_64673630 0.47 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
KIAA0101
chr2_-_64371546 0.47 ENST00000358912.4
PELI1
pellino E3 ubiquitin protein ligase 1
chr14_-_24047965 0.45 ENST00000397118.3
ENST00000356300.4
JPH4
junctophilin 4
chr2_-_38978492 0.45 ENST00000409276.1
ENST00000446327.2
ENST00000313117.6
SRSF7
serine/arginine-rich splicing factor 7
chr2_-_68479614 0.45 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chrX_-_74376108 0.45 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr4_-_73434498 0.45 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr5_+_52776228 0.44 ENST00000256759.3
FST
follistatin
chr1_+_154300217 0.44 ENST00000368489.3
ATP8B2
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr17_-_29151794 0.44 ENST00000324238.6
CRLF3
cytokine receptor-like factor 3
chr12_-_53625958 0.44 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG
retinoic acid receptor, gamma
chr6_-_57087042 0.43 ENST00000317483.3
RAB23
RAB23, member RAS oncogene family
chr1_-_197169672 0.43 ENST00000367405.4
ZBTB41
zinc finger and BTB domain containing 41
chr11_-_116968987 0.43 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3
SIK family kinase 3
chr14_+_101193164 0.43 ENST00000341267.4
DLK1
delta-like 1 homolog (Drosophila)
chr7_-_134001663 0.42 ENST00000378509.4
SLC35B4
solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
chr14_+_37131058 0.42 ENST00000361487.6
PAX9
paired box 9
chr3_+_171758344 0.42 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr21_+_39628655 0.42 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr10_+_112836779 0.42 ENST00000280155.2
ADRA2A
adrenoceptor alpha 2A
chr10_-_23003460 0.42 ENST00000376573.4
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr12_-_133464151 0.42 ENST00000315585.7
ENST00000266880.7
ENST00000443047.2
ENST00000432561.2
ENST00000450056.2
CHFR
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chrX_+_37208521 0.41 ENST00000378628.4
PRRG1
proline rich Gla (G-carboxyglutamic acid) 1
chr20_-_21494654 0.41 ENST00000377142.4
NKX2-2
NK2 homeobox 2
chrX_+_150151752 0.41 ENST00000325307.7
HMGB3
high mobility group box 3
chr3_-_9291063 0.41 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr9_-_136242909 0.41 ENST00000371991.3
ENST00000545297.1
SURF4
surfeit 4
chr7_+_77469439 0.41 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr5_+_115177178 0.41 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr8_+_42752053 0.39 ENST00000307602.4
HOOK3
hook microtubule-tethering protein 3
chr19_-_11450249 0.39 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr5_-_131563501 0.39 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr1_+_199996702 0.39 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr17_-_33416231 0.39 ENST00000584655.1
ENST00000447669.2
ENST00000315249.7
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr12_-_77459306 0.39 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F7
E2F transcription factor 7
chr1_+_173684047 0.38 ENST00000546011.1
ENST00000209884.4
KLHL20
kelch-like family member 20
chr12_-_42632016 0.37 ENST00000442791.3
ENST00000327791.4
ENST00000534854.2
ENST00000380788.3
ENST00000380790.4
YAF2
YY1 associated factor 2
chr14_+_96829814 0.37 ENST00000555181.1
ENST00000553699.1
ENST00000554182.1
GSKIP
GSK3B interacting protein
chr2_-_209119831 0.37 ENST00000345146.2
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr12_-_46662772 0.37 ENST00000549049.1
ENST00000439706.1
ENST00000398637.5
SLC38A1
solute carrier family 38, member 1
chr3_+_15468862 0.37 ENST00000396842.2
EAF1
ELL associated factor 1
chr12_+_62654119 0.36 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15
ubiquitin specific peptidase 15
chr12_+_50898881 0.36 ENST00000301180.5
DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr2_-_61765315 0.36 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr10_+_89264625 0.36 ENST00000371996.4
ENST00000371994.4
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr19_+_11200038 0.36 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
LDLR
low density lipoprotein receptor
chr3_+_150126101 0.36 ENST00000361875.3
ENST00000361136.2
TSC22D2
TSC22 domain family, member 2
chr9_-_71155783 0.35 ENST00000377311.3
TMEM252
transmembrane protein 252
chr1_+_6673745 0.35 ENST00000377648.4
PHF13
PHD finger protein 13
chr6_+_125283566 0.34 ENST00000521654.2
RNF217
ring finger protein 217
chr2_-_227664474 0.34 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr17_-_79885576 0.34 ENST00000574686.1
ENST00000357736.4
MAFG
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr6_-_84140757 0.34 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr10_+_12171721 0.33 ENST00000379020.4
ENST00000379017.3
SEC61A2
Sec61 alpha 2 subunit (S. cerevisiae)
chr12_-_39299406 0.33 ENST00000331366.5
CPNE8
copine VIII
chr13_-_36050819 0.33 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr5_+_78908233 0.32 ENST00000453514.1
ENST00000423041.2
ENST00000504233.1
ENST00000428308.2
PAPD4
PAP associated domain containing 4
chr11_+_117049445 0.32 ENST00000324225.4
ENST00000532960.1
SIDT2
SID1 transmembrane family, member 2
chr12_-_82153087 0.32 ENST00000547623.1
ENST00000549396.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr1_+_113217043 0.32 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr17_-_42767115 0.32 ENST00000315286.8
ENST00000588210.1
ENST00000457422.2
CCDC43
coiled-coil domain containing 43
chr2_+_20646824 0.32 ENST00000272233.4
RHOB
ras homolog family member B
chr2_+_120517174 0.32 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr15_+_27111510 0.32 ENST00000335625.5
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr3_+_196594727 0.32 ENST00000445299.2
ENST00000323460.5
ENST00000419026.1
SENP5
SUMO1/sentrin specific peptidase 5
chrX_-_131352152 0.32 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr10_+_64893039 0.32 ENST00000277746.6
ENST00000435510.2
NRBF2
nuclear receptor binding factor 2
chr1_+_64058939 0.32 ENST00000371084.3
PGM1
phosphoglucomutase 1
chr17_-_71640227 0.31 ENST00000388726.3
ENST00000392650.3
SDK2
sidekick cell adhesion molecule 2
chr8_+_38614807 0.31 ENST00000330691.6
ENST00000348567.4
TACC1
transforming, acidic coiled-coil containing protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAAACA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.7 2.6 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.6 1.7 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.4 1.7 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.4 1.1 GO:0072034 primary prostatic bud elongation(GO:0060516) renal vesicle induction(GO:0072034)
0.3 2.2 GO:1903232 melanosome assembly(GO:1903232)
0.3 1.8 GO:0021824 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.3 1.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3 0.8 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.3 0.8 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.3 0.8 GO:0042369 vitamin D catabolic process(GO:0042369)
0.2 0.9 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.2 0.9 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.2 1.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 2.0 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.2 0.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 0.7 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 0.5 GO:0033341 regulation of collagen binding(GO:0033341)
0.2 0.9 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.2 0.7 GO:0032811 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.2 0.5 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 0.6 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.2 0.6 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.2 1.4 GO:0015803 branched-chain amino acid transport(GO:0015803)
0.1 0.9 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.4 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.8 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.4 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.4 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 1.6 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.5 GO:0042853 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.1 0.4 GO:0003162 atrioventricular node development(GO:0003162)
0.1 1.1 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.1 0.8 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 0.2 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.7 GO:0051643 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) secretory granule localization(GO:0032252) endoplasmic reticulum localization(GO:0051643)
0.1 0.8 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.5 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.5 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.3 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016) negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.6 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.2 GO:1903308 regulation of chromatin modification(GO:1903308)
0.1 0.6 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.7 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 0.4 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.8 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 2.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.3 GO:1901143 insulin catabolic process(GO:1901143)
0.1 1.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 0.3 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.1 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.7 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.1 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.1 0.3 GO:0071484 cellular response to light intensity(GO:0071484)
0.1 0.3 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.7 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.8 GO:0051597 response to methylmercury(GO:0051597)
0.1 1.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.6 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 1.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.2 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.1 0.1 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.3 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.2 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.2 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.1 0.3 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.1 0.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.5 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.5 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.6 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.6 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.1 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
0.1 0.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.4 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.3 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.2 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0060374 mast cell differentiation(GO:0060374)
0.0 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.5 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.5 GO:0015886 heme transport(GO:0015886)
0.0 0.3 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.0 0.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.3 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.2 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.0 0.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.0 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.0 0.3 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.3 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.0 0.7 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.6 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 1.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 2.0 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.5 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.7 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 1.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.2 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.3 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.5 GO:0045116 protein neddylation(GO:0045116)
0.0 1.1 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 1.0 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.1 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.2 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 0.1 GO:0031337 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:1901796 regulation of signal transduction by p53 class mediator(GO:1901796)
0.0 0.1 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.5 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.2 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.5 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 2.4 GO:0048675 axon extension(GO:0048675)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.7 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.7 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 0.4 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.8 GO:0007129 synapsis(GO:0007129)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.9 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.0 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 1.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.4 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.3 GO:0060119 inner ear receptor cell development(GO:0060119)
0.0 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.6 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.3 GO:1901216 positive regulation of neuron death(GO:1901216)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.0 GO:0032639 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0050821 protein stabilization(GO:0050821)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0035418 protein localization to synapse(GO:0035418)
0.0 0.3 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.4 GO:0031648 protein destabilization(GO:0031648)
0.0 0.3 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.1 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.1 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.0 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085) positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.1 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891) protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386) cellular response to mineralocorticoid stimulus(GO:0071389)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 0.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 2.1 GO:0031905 early endosome lumen(GO:0031905)
0.3 0.9 GO:0031523 Myb complex(GO:0031523)
0.2 0.8 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.2 0.5 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.2 0.5 GO:0097447 dendritic tree(GO:0097447)
0.1 0.4 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.3 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.1 0.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.2 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.1 1.0 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 1.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.6 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 0.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.1 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.7 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.2 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 2.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 1.2 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 2.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 1.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 2.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.5 2.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.5 1.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.4 2.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.4 1.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.3 1.3 GO:0008431 vitamin E binding(GO:0008431)
0.3 2.1 GO:1990254 keratin filament binding(GO:1990254)
0.3 0.8 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.3 0.8 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 0.7 GO:0098808 mRNA cap binding(GO:0098808)
0.2 0.7 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 0.7 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 0.6 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2 0.6 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.2 0.8 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.6 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.4 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.4 GO:0019961 interferon binding(GO:0019961)
0.1 0.4 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1 0.4 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.1 0.9 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.1 2.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 1.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 1.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.3 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.1 0.7 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.8 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.2 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.1 0.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.8 GO:0000150 recombinase activity(GO:0000150)
0.1 0.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 1.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.3 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.3 GO:1901474 azole transmembrane transporter activity(GO:1901474)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 2.0 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.4 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.7 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 2.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.4 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 2.2 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 1.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.7 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.0 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.0 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0060089 receptor activity(GO:0004872) molecular transducer activity(GO:0060089)
0.0 1.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.4 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0008483 transaminase activity(GO:0008483)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 3.2 PID AURORA B PATHWAY Aurora B signaling
0.0 2.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.2 PID MYC PATHWAY C-MYC pathway
0.0 2.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.8 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID FOXO PATHWAY FoxO family signaling
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID ENDOTHELIN PATHWAY Endothelins
0.0 2.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 REACTOME SIGNAL AMPLIFICATION Genes involved in Signal amplification
0.2 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 2.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 4.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 2.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.0 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.8 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle