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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for GZF1

Z-value: 0.38

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Transcription factors associated with GZF1

Gene Symbol Gene ID Gene Info
ENSG00000125812.11 GDNF inducible zinc finger protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GZF1hg19_v2_chr20_+_23342783_233429570.383.9e-02Click!

Activity profile of GZF1 motif

Sorted Z-values of GZF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_101918153 2.01 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
chromosome 11 open reading frame 70
chr20_+_42086525 0.97 ENST00000244020.3
serine/arginine-rich splicing factor 6
chr1_+_79115503 0.96 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
interferon-induced protein 44
chr9_-_124976185 0.79 ENST00000464484.2
LIM homeobox 6
chr9_-_124976154 0.79 ENST00000482062.1
LIM homeobox 6
chr14_-_92413727 0.68 ENST00000267620.10
fibulin 5
chr12_+_104458235 0.65 ENST00000229330.4
host cell factor C2
chr3_-_114035026 0.64 ENST00000570269.1
RP11-553L6.5
chr9_+_96338647 0.62 ENST00000359246.4
PHD finger protein 2
chr18_-_53303123 0.61 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
transcription factor 4
chr9_+_96338860 0.51 ENST00000375376.4
PHD finger protein 2
chr1_-_32801825 0.50 ENST00000329421.7
MARCKS-like 1
chr3_-_79816965 0.46 ENST00000464233.1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr1_-_144995074 0.40 ENST00000534536.1
phosphodiesterase 4D interacting protein
chr19_-_36545128 0.38 ENST00000538849.1
THAP domain containing 8
chr3_+_30647994 0.36 ENST00000295754.5
transforming growth factor, beta receptor II (70/80kDa)
chr14_-_92413353 0.36 ENST00000556154.1
fibulin 5
chr14_-_21979428 0.34 ENST00000538267.1
ENST00000298717.4
methyltransferase like 3
chr1_-_144994909 0.32 ENST00000369347.4
ENST00000369354.3
phosphodiesterase 4D interacting protein
chr1_-_11107280 0.28 ENST00000400897.3
ENST00000400898.3
mannan-binding lectin serine peptidase 2
chr15_+_44580955 0.25 ENST00000345795.2
ENST00000360824.3
cancer susceptibility candidate 4
chr1_-_144995002 0.24 ENST00000369356.4
phosphodiesterase 4D interacting protein
chr20_-_31331212 0.24 ENST00000474815.2
ENST00000446419.2
COMM domain containing 7
chr14_-_53619816 0.24 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD domain containing 1
chr3_+_30648066 0.22 ENST00000359013.4
transforming growth factor, beta receptor II (70/80kDa)
chr17_-_70588936 0.21 ENST00000453722.2
long intergenic non-protein coding RNA 511
chr1_+_41174988 0.20 ENST00000372652.1
nuclear transcription factor Y, gamma
chrX_+_102883620 0.19 ENST00000372626.3
transcription elongation factor A (SII)-like 1
chr16_-_30582888 0.18 ENST00000563707.1
ENST00000567855.1
zinc finger protein 688
chr10_+_60028818 0.18 ENST00000333926.5
CDGSH iron sulfur domain 1
chr16_+_67876180 0.17 ENST00000303596.1
THAP domain containing 11
chr8_+_23430157 0.17 ENST00000399967.3
FP15737
chr2_-_27603582 0.14 ENST00000323703.6
ENST00000436006.1
zinc finger protein 513
chr10_+_89264625 0.13 ENST00000371996.4
ENST00000371994.4
multiple inositol-polyphosphate phosphatase 1
chr10_+_14880287 0.12 ENST00000437161.2
heat shock 70kDa protein 14
chr9_-_14308004 0.11 ENST00000493697.1
nuclear factor I/B
chr1_-_144994840 0.11 ENST00000369351.3
ENST00000369349.3
phosphodiesterase 4D interacting protein
chr4_-_89619386 0.11 ENST00000323061.5
nucleosome assembly protein 1-like 5
chr19_+_36157715 0.10 ENST00000379013.2
ENST00000222275.2
uroplakin 1A
chr3_+_51705222 0.10 ENST00000457573.1
ENST00000341333.5
ENST00000412249.1
ENST00000425781.1
ENST00000415259.1
ENST00000395057.1
ENST00000416589.1
testis expressed 264
chr1_-_2461684 0.08 ENST00000378453.3
hes family bHLH transcription factor 5
chr5_+_92919043 0.07 ENST00000327111.3
nuclear receptor subfamily 2, group F, member 1
chr10_-_126849588 0.05 ENST00000411419.2
C-terminal binding protein 2
chr16_-_46797149 0.05 ENST00000536476.1
myosin light chain kinase 3
chr22_-_43355858 0.05 ENST00000402229.1
ENST00000407585.1
ENST00000453079.1
protein kinase C and casein kinase substrate in neurons 2
chr10_-_126849068 0.03 ENST00000494626.2
ENST00000337195.5
C-terminal binding protein 2
chr10_-_14880566 0.03 ENST00000378442.1
cerebral dopamine neurotrophic factor
chr14_+_22293618 0.03 ENST00000390432.2
T cell receptor alpha variable 10
chr16_-_70285797 0.02 ENST00000435634.1
exosome component 6
chr3_-_170588163 0.02 ENST00000295830.8
ribosomal protein L22-like 1
chr19_-_52150053 0.02 ENST00000599649.1
ENST00000429354.3
ENST00000360844.6
ENST00000222107.4
SIGLEC5
sialic acid binding Ig-like lectin 14
sialic acid binding Ig-like lectin 5
chr4_-_147443043 0.02 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
solute carrier family 10, member 7
chr19_-_10426663 0.01 ENST00000541276.1
ENST00000393708.3
ENST00000494368.1
ferredoxin 1-like
chr7_+_102004322 0.01 ENST00000496391.1
PRKR interacting protein 1 (IL11 inducible)

Network of associatons between targets according to the STRING database.

First level regulatory network of GZF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.2 0.6 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.2 0.5 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 1.6 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.0 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 1.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0071953 elastic fiber(GO:0071953)
0.1 0.3 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.3 GO:0001855 complement component C4b binding(GO:0001855)
0.1 1.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 1.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis