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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HAND1

Z-value: 0.51

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Transcription factors associated with HAND1

Gene Symbol Gene ID Gene Info
HAND1
ENSG00000113196.2 heart and neural crest derivatives expressed 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HAND1hg19_v2_chr5_-_153857819_1538578240.019.5e-01Click!

Activity profile of HAND1 motif

Sorted Z-values of HAND1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_57630873 2.24 ENST00000556732.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr2_+_210444142 1.50 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr2_+_228678550 1.17 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr2_-_27718052 0.96 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr17_-_43025005 0.86 ENST00000587309.1
ENST00000593135.1
ENST00000339151.4
KIF18B
kinesin family member 18B
chr2_+_113816215 0.83 ENST00000346807.3
IL36RN
interleukin 36 receptor antagonist
chr11_+_118826999 0.79 ENST00000264031.2
UPK2
uroplakin 2
chr11_+_124932955 0.79 ENST00000403796.2
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr11_+_124932986 0.78 ENST00000407458.1
ENST00000298280.5
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chrX_+_49832231 0.76 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr20_-_56285595 0.75 ENST00000395816.3
ENST00000347215.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr11_+_124933191 0.75 ENST00000532000.1
ENST00000308074.4
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr20_-_56286479 0.75 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr7_+_110731062 0.72 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr6_-_112194484 0.70 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN
FYN oncogene related to SRC, FGR, YES
chr17_+_6347729 0.69 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr11_-_102496063 0.69 ENST00000260228.2
MMP20
matrix metallopeptidase 20
chr17_+_6347761 0.69 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
FAM64A
family with sequence similarity 64, member A
chr12_+_49717019 0.68 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
TROAP
trophinin associated protein
chr2_+_204732666 0.66 ENST00000295854.6
ENST00000472206.1
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr13_-_30881134 0.63 ENST00000380617.3
ENST00000441394.1
KATNAL1
katanin p60 subunit A-like 1
chr1_-_52870059 0.56 ENST00000371566.1
ORC1
origin recognition complex, subunit 1
chr1_-_52870104 0.53 ENST00000371568.3
ORC1
origin recognition complex, subunit 1
chr11_+_369804 0.53 ENST00000329962.6
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr18_+_12407895 0.53 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
SLMO1
slowmo homolog 1 (Drosophila)
chr14_+_96722539 0.49 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr1_-_214638146 0.48 ENST00000543945.1
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr2_-_208031943 0.47 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr9_-_139640458 0.45 ENST00000476567.1
LCN6
lipocalin 6
chr22_+_25003568 0.44 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr11_-_64527425 0.43 ENST00000377432.3
PYGM
phosphorylase, glycogen, muscle
chr2_+_90153696 0.42 ENST00000417279.2
IGKV3D-15
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr17_+_43922241 0.41 ENST00000329196.5
SPPL2C
signal peptide peptidase like 2C
chr1_+_65775204 0.40 ENST00000371069.4
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr17_-_45908875 0.39 ENST00000351111.2
ENST00000414011.1
MRPL10
mitochondrial ribosomal protein L10
chr2_+_201997595 0.38 ENST00000470178.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr15_-_76304731 0.38 ENST00000394907.3
NRG4
neuregulin 4
chr14_-_53331239 0.38 ENST00000553663.1
FERMT2
fermitin family member 2
chr14_+_96722152 0.38 ENST00000216629.6
BDKRB1
bradykinin receptor B1
chr21_+_31768348 0.37 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr22_+_25003606 0.37 ENST00000432867.1
GGT1
gamma-glutamyltransferase 1
chr19_+_507299 0.36 ENST00000359315.5
TPGS1
tubulin polyglutamylase complex subunit 1
chr12_-_10955226 0.35 ENST00000240687.2
TAS2R7
taste receptor, type 2, member 7
chr19_+_12862486 0.35 ENST00000549706.1
BEST2
bestrophin 2
chr1_+_44444865 0.34 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr12_+_26111823 0.34 ENST00000381352.3
ENST00000535907.1
ENST00000405154.2
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr22_+_24999114 0.34 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
GGT1
gamma-glutamyltransferase 1
chr10_+_99344104 0.33 ENST00000555577.1
ENST00000370649.3
PI4K2A
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr10_+_72972281 0.32 ENST00000335350.6
UNC5B
unc-5 homolog B (C. elegans)
chr22_+_25003626 0.31 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1
gamma-glutamyltransferase 1
chr19_+_12862604 0.31 ENST00000553030.1
BEST2
bestrophin 2
chr20_+_22034809 0.31 ENST00000449427.1
RP11-125P18.1
RP11-125P18.1
chr8_-_93029520 0.30 ENST00000521553.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_2323290 0.30 ENST00000381153.3
C11orf21
chromosome 11 open reading frame 21
chr17_-_64216748 0.29 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr6_+_124125286 0.28 ENST00000368416.1
ENST00000368417.1
ENST00000546092.1
NKAIN2
Na+/K+ transporting ATPase interacting 2
chr11_-_2323089 0.28 ENST00000456145.2
C11orf21
chromosome 11 open reading frame 21
chr10_-_118032697 0.28 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr19_+_36359341 0.27 ENST00000221891.4
APLP1
amyloid beta (A4) precursor-like protein 1
chr10_-_99393242 0.27 ENST00000370635.3
ENST00000478953.1
ENST00000335628.3
MORN4
MORN repeat containing 4
chr10_-_99393208 0.27 ENST00000307450.6
MORN4
MORN repeat containing 4
chr12_-_110271178 0.26 ENST00000261740.2
ENST00000392719.2
ENST00000346520.2
TRPV4
transient receptor potential cation channel, subfamily V, member 4
chr9_+_72658490 0.25 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr7_+_76139833 0.25 ENST00000257632.5
UPK3B
uroplakin 3B
chr2_+_201997492 0.25 ENST00000494258.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr7_-_116963334 0.25 ENST00000265441.3
WNT2
wingless-type MMTV integration site family member 2
chr11_-_26743546 0.25 ENST00000280467.6
ENST00000396005.3
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr6_+_35996859 0.24 ENST00000472333.1
MAPK14
mitogen-activated protein kinase 14
chr2_-_197791441 0.24 ENST00000409475.1
ENST00000354764.4
ENST00000374738.3
PGAP1
post-GPI attachment to proteins 1
chr3_+_141103634 0.23 ENST00000507722.1
ZBTB38
zinc finger and BTB domain containing 38
chr2_+_204732487 0.23 ENST00000302823.3
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr10_+_131934643 0.23 ENST00000331244.5
ENST00000368644.1
GLRX3
glutaredoxin 3
chr17_-_40337470 0.23 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr17_-_36358166 0.22 ENST00000537432.1
TBC1D3
TBC1 domain family, member 3
chr16_+_6069586 0.21 ENST00000547372.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_-_102462565 0.21 ENST00000370103.4
OLFM3
olfactomedin 3
chr9_-_123555655 0.20 ENST00000340778.5
ENST00000453291.1
ENST00000608872.1
FBXW2
F-box and WD repeat domain containing 2
chr12_-_53730147 0.20 ENST00000536324.2
SP7
Sp7 transcription factor
chr3_-_9811595 0.19 ENST00000256460.3
CAMK1
calcium/calmodulin-dependent protein kinase I
chr20_+_123010 0.19 ENST00000382398.3
DEFB126
defensin, beta 126
chr16_-_10652993 0.19 ENST00000536829.1
EMP2
epithelial membrane protein 2
chr12_+_68042517 0.19 ENST00000393555.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr10_-_118032979 0.19 ENST00000355422.6
GFRA1
GDNF family receptor alpha 1
chr1_+_11249398 0.18 ENST00000376819.3
ANGPTL7
angiopoietin-like 7
chr3_+_123813509 0.18 ENST00000460856.1
ENST00000240874.3
KALRN
kalirin, RhoGEF kinase
chr2_-_128784846 0.18 ENST00000259235.3
ENST00000357702.5
ENST00000424298.1
SAP130
Sin3A-associated protein, 130kDa
chr9_-_115095123 0.17 ENST00000458258.1
PTBP3
polypyrimidine tract binding protein 3
chr8_+_79428539 0.17 ENST00000352966.5
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr7_-_81399329 0.17 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_+_45478568 0.16 ENST00000428106.1
UROD
uroporphyrinogen decarboxylase
chrX_+_70364667 0.16 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr11_+_67171391 0.16 ENST00000312390.5
TBC1D10C
TBC1 domain family, member 10C
chr12_+_98909260 0.16 ENST00000556029.1
TMPO
thymopoietin
chr1_+_207262578 0.15 ENST00000243611.5
ENST00000367076.3
C4BPB
complement component 4 binding protein, beta
chr1_+_207262627 0.15 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr1_-_155904187 0.15 ENST00000368321.3
ENST00000368320.3
KIAA0907
KIAA0907
chr12_-_53729525 0.15 ENST00000303846.3
SP7
Sp7 transcription factor
chr19_-_37701386 0.15 ENST00000527838.1
ENST00000591492.1
ENST00000532828.2
ZNF585B
zinc finger protein 585B
chr5_-_147286065 0.15 ENST00000318315.4
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr7_+_141490017 0.15 ENST00000247883.4
TAS2R5
taste receptor, type 2, member 5
chr6_+_44191507 0.14 ENST00000371724.1
ENST00000371713.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr1_+_207262540 0.14 ENST00000452902.2
C4BPB
complement component 4 binding protein, beta
chr15_-_31393910 0.14 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr1_+_207262170 0.14 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr5_+_143584814 0.13 ENST00000507359.3
KCTD16
potassium channel tetramerization domain containing 16
chr7_-_142207004 0.13 ENST00000426318.2
TRBV10-2
T cell receptor beta variable 10-2
chr5_-_150466692 0.12 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr9_-_35828576 0.12 ENST00000377984.2
ENST00000423537.2
ENST00000472182.1
FAM221B
family with sequence similarity 221, member B
chr11_+_67171358 0.12 ENST00000526387.1
TBC1D10C
TBC1 domain family, member 10C
chr7_-_2883928 0.11 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr2_+_201997676 0.11 ENST00000462763.1
ENST00000479953.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr16_+_70328680 0.11 ENST00000563206.1
ENST00000451014.3
ENST00000568625.1
DDX19B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
chr6_-_53013620 0.11 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chrX_+_15767971 0.11 ENST00000479740.1
ENST00000454127.2
CA5B
carbonic anhydrase VB, mitochondrial
chr11_+_67171548 0.10 ENST00000542590.1
TBC1D10C
TBC1 domain family, member 10C
chr20_+_816695 0.10 ENST00000246100.3
FAM110A
family with sequence similarity 110, member A
chr20_+_29956369 0.10 ENST00000253381.2
DEFB118
defensin, beta 118
chr2_-_42588338 0.09 ENST00000234301.2
COX7A2L
cytochrome c oxidase subunit VIIa polypeptide 2 like
chr11_+_112130988 0.09 ENST00000595053.1
AP002884.2
LOC100132686 protein; Uncharacterized protein
chr10_+_103113840 0.09 ENST00000393441.4
ENST00000408038.2
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
chr3_+_148415571 0.09 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
AGTR1
angiotensin II receptor, type 1
chr2_-_25475120 0.09 ENST00000380746.4
ENST00000402667.1
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr11_+_111411384 0.09 ENST00000375615.3
ENST00000525126.1
ENST00000436913.2
ENST00000533265.1
LAYN
layilin
chr9_+_125376948 0.08 ENST00000297913.2
OR1Q1
olfactory receptor, family 1, subfamily Q, member 1
chr20_+_1115821 0.08 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr11_-_19223523 0.08 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr12_+_53848549 0.07 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
PCBP2
poly(rC) binding protein 2
chr10_+_103113802 0.06 ENST00000370187.3
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
chr10_+_118350468 0.06 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1
pancreatic lipase-related protein 1
chr11_+_2323349 0.06 ENST00000381121.3
TSPAN32
tetraspanin 32
chr7_+_96634850 0.06 ENST00000518156.2
DLX6
distal-less homeobox 6
chr12_+_110338063 0.06 ENST00000405876.4
TCHP
trichoplein, keratin filament binding
chr9_-_25678856 0.05 ENST00000358022.3
TUSC1
tumor suppressor candidate 1
chr11_+_2323236 0.05 ENST00000182290.4
TSPAN32
tetraspanin 32
chr16_-_31147020 0.05 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8
protease, serine, 8
chr17_+_11924129 0.05 ENST00000353533.5
ENST00000415385.3
MAP2K4
mitogen-activated protein kinase kinase 4
chr7_-_20256965 0.04 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr16_+_6069664 0.04 ENST00000422070.4
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr17_+_66624280 0.04 ENST00000585484.1
RP11-118B18.1
RP11-118B18.1
chrX_-_133930285 0.03 ENST00000486347.1
ENST00000343004.5
FAM122B
family with sequence similarity 122B
chr21_+_34602377 0.03 ENST00000342101.3
ENST00000413881.1
ENST00000443073.1
IFNAR2
interferon (alpha, beta and omega) receptor 2
chr1_-_52344471 0.03 ENST00000352171.7
ENST00000354831.7
NRD1
nardilysin (N-arginine dibasic convertase)
chr16_-_4303767 0.03 ENST00000573268.1
ENST00000573042.1
RP11-95P2.1
RP11-95P2.1
chr10_+_118350522 0.03 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
PNLIPRP1
pancreatic lipase-related protein 1
chr7_-_142583506 0.03 ENST00000359396.3
TRPV6
transient receptor potential cation channel, subfamily V, member 6
chr1_+_27719148 0.02 ENST00000374024.3
GPR3
G protein-coupled receptor 3
chr3_-_157251383 0.02 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr10_+_99344071 0.01 ENST00000370647.4
ENST00000370646.4
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr1_+_28261533 0.01 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr7_+_140378955 0.00 ENST00000473512.1
ADCK2
aarF domain containing kinase 2
chr17_+_7836398 0.00 ENST00000565740.1
CNTROB
centrobin, centrosomal BRCA2 interacting protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HAND1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 0.7 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.2 2.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 0.9 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 1.5 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.8 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.1 1.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.3 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.3 GO:0072566 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338) positive regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000340)
0.1 0.7 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.5 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.6 GO:1903027 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 0.7 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.3 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.3 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0 0.2 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.2 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.5 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.3 GO:0034392 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 1.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.5 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.2 GO:0070836 caveola assembly(GO:0070836)
0.0 0.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 2.2 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 1.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.4 GO:0033622 integrin activation(GO:0033622)
0.0 0.7 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.4 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.3 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 2.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.5 GO:0035838 growing cell tip(GO:0035838)
0.1 0.9 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 0.4 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 1.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.0 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 2.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0031527 filopodium membrane(GO:0031527)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.3 2.3 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.3 0.9 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 0.8 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.7 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.4 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.3 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.3 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 1.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.5 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 2.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.5 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.2 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 1.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.9 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling