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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HIC1

Z-value: 0.78

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Transcription factors associated with HIC1

Gene Symbol Gene ID Gene Info
ENSG00000177374.8 HIC ZBTB transcriptional repressor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIC1hg19_v2_chr17_+_1958388_1958404,
hg19_v2_chr17_+_1959369_1959604
0.029.1e-01Click!

Activity profile of HIC1 motif

Sorted Z-values of HIC1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_2160611 1.71 ENST00000416167.2
insulin-like growth factor 2 (somatomedin A)
chr13_+_110959598 1.11 ENST00000360467.5
collagen, type IV, alpha 2
chr12_+_26274917 1.03 ENST00000538142.1
sarcospan
chr18_+_77623668 0.88 ENST00000316249.3
potassium voltage-gated channel, subfamily G, member 2
chr1_+_1551220 0.77 ENST00000378712.1
mindbomb E3 ubiquitin protein ligase 2
chr11_+_120382417 0.75 ENST00000527524.2
ENST00000375081.2
glutamate receptor, ionotropic, kainate 4
Uncharacterized protein
chr4_+_3768075 0.75 ENST00000509482.1
ENST00000330055.5
adrenoceptor alpha 2C
chr12_-_132905789 0.69 ENST00000328957.8
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr7_+_73082152 0.68 ENST00000324941.4
ENST00000451519.1
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr3_+_52280173 0.67 ENST00000296487.4
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr10_+_116853201 0.67 ENST00000527407.1
attractin-like 1
chr9_+_22446814 0.63 ENST00000325870.2
DMRT-like family A1
chr5_+_6633456 0.60 ENST00000274192.5
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
chr3_+_52280220 0.60 ENST00000409502.3
ENST00000323588.4
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr6_+_159590423 0.59 ENST00000297267.9
ENST00000340366.6
fibronectin type III domain containing 1
chr4_-_175443788 0.59 ENST00000541923.1
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr4_-_109684120 0.58 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
ethanolamine-phosphate phospho-lyase
chrX_-_45710920 0.55 ENST00000456532.1
RP5-1158E12.3
chr10_+_72238517 0.55 ENST00000263563.6
phosphatase domain containing, paladin 1
chr5_+_6633534 0.54 ENST00000537411.1
ENST00000538824.1
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
chr13_-_44361025 0.54 ENST00000261488.6
ecto-NOX disulfide-thiol exchanger 1
chr9_+_78505554 0.54 ENST00000545128.1
proprotein convertase subtilisin/kexin type 5
chr13_-_45992541 0.53 ENST00000522438.1
solute carrier family 25, member 30
chr1_-_62784935 0.52 ENST00000354381.3
KN motif and ankyrin repeat domains 4
chr16_+_1662326 0.52 ENST00000397412.3
Crm, cramped-like (Drosophila)
chr13_+_28712614 0.52 ENST00000380958.3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr4_-_175443484 0.50 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr10_+_71562180 0.49 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
collagen, type XIII, alpha 1
chr1_+_6845384 0.48 ENST00000303635.7
calmodulin binding transcription activator 1
chr7_+_70597109 0.48 ENST00000333538.5
Williams-Beuren syndrome chromosome region 17
chrX_+_38420783 0.45 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
tetraspanin 7
chr16_-_1661988 0.45 ENST00000426508.2
intraflagellar transport 140 homolog (Chlamydomonas)
chr8_+_27491381 0.44 ENST00000337221.4
scavenger receptor class A, member 3
chr17_-_80656528 0.44 ENST00000538809.2
ENST00000269347.6
ENST00000571995.1
RAB40B, member RAS oncogene family
chr2_-_165477971 0.43 ENST00000446413.2
growth factor receptor-bound protein 14
chr16_+_1756162 0.43 ENST00000250894.4
ENST00000356010.5
mitogen-activated protein kinase 8 interacting protein 3
chr1_-_43919346 0.43 ENST00000372430.3
ENST00000372433.1
ENST00000372434.1
ENST00000486909.1
hydroxypyruvate isomerase (putative)
chr11_+_119019722 0.42 ENST00000307417.3
ATP-binding cassette, sub-family G (WHITE), member 4
chr22_-_50689640 0.42 ENST00000448072.1
histone deacetylase 10
chr10_+_116853091 0.42 ENST00000526946.1
attractin-like 1
chr16_+_25703274 0.41 ENST00000331351.5
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr10_+_11784360 0.41 ENST00000379215.4
ENST00000420401.1
enoyl CoA hydratase domain containing 3
chr6_-_41863098 0.41 ENST00000373006.1
ubiquitin specific peptidase 49
chr1_-_6240183 0.41 ENST00000262450.3
ENST00000378021.1
chromodomain helicase DNA binding protein 5
chr11_-_2160180 0.41 ENST00000381406.4
insulin-like growth factor 2 (somatomedin A)
chr17_+_4402133 0.40 ENST00000329078.3
spinster homolog 2 (Drosophila)
chr12_+_130646999 0.40 ENST00000539839.1
ENST00000229030.4
frizzled family receptor 10
chr3_-_52739762 0.40 ENST00000487642.1
ENST00000464705.1
ENST00000491606.1
ENST00000489119.1
ENST00000478968.2
glycosyltransferase 8 domain containing 1
chr15_+_33603147 0.40 ENST00000415757.3
ENST00000389232.4
ryanodine receptor 3
chr2_-_72375167 0.39 ENST00000001146.2
cytochrome P450, family 26, subfamily B, polypeptide 1
chrX_-_128788914 0.38 ENST00000429967.1
ENST00000307484.6
apelin
chr22_-_45404819 0.38 ENST00000447824.3
ENST00000404079.2
ENST00000420689.1
ENST00000403565.1
PHD finger protein 21B
chr10_+_122216316 0.37 ENST00000398250.1
ENST00000439221.1
ENST00000398248.1
phosphatidic acid phosphatase type 2 domain containing 1A
chr14_+_105992906 0.37 ENST00000392519.2
transmembrane protein 121
chr1_-_85358850 0.37 ENST00000370611.3
lysophosphatidic acid receptor 3
chr19_+_41860047 0.37 ENST00000604123.1
transmembrane protein 91
chr1_-_43919573 0.37 ENST00000372432.1
ENST00000372425.4
ENST00000583037.1
hydroxypyruvate isomerase (putative)
chr22_+_23412479 0.37 ENST00000248996.4
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr10_-_126432821 0.37 ENST00000280780.6
family with sequence similarity 53, member B
chr2_-_10220538 0.36 ENST00000381813.4
cystin 1
chr1_+_8378140 0.36 ENST00000377479.2
solute carrier family 45, member 1
chr20_+_23016057 0.36 ENST00000255008.3
somatostatin receptor 4
chr3_-_52740012 0.35 ENST00000407584.3
ENST00000266014.5
glycosyltransferase 8 domain containing 1
chr14_+_33408449 0.35 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
neuronal PAS domain protein 3
chr11_+_65554493 0.35 ENST00000335987.3
ovo-like zinc finger 1
chr5_-_168727713 0.35 ENST00000404867.3
slit homolog 3 (Drosophila)
chr4_+_148653206 0.35 ENST00000336498.3
Rho GTPase activating protein 10
chrX_+_38420623 0.35 ENST00000378482.2
tetraspanin 7
chr8_-_23261589 0.34 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
lysyl oxidase-like 2
chr3_+_137483579 0.34 ENST00000306087.1
SRY (sex determining region Y)-box 14
chr17_+_7621045 0.34 ENST00000570791.1
dynein, axonemal, heavy chain 2
chr9_+_131182697 0.34 ENST00000372838.4
ENST00000411852.1
cerebral endothelial cell adhesion molecule
chr5_+_111755280 0.34 ENST00000600409.1
EPB41L4A antisense RNA 2 (head to head)
chr12_-_45270151 0.34 ENST00000429094.2
NEL-like 2 (chicken)
chr18_-_21242774 0.33 ENST00000322980.9
ankyrin repeat domain 29
chr19_+_35521616 0.33 ENST00000595652.1
sodium channel, voltage-gated, type I, beta subunit
chr3_+_53528659 0.33 ENST00000350061.5
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr4_-_175443943 0.33 ENST00000296522.6
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr10_+_17271266 0.33 ENST00000224237.5
vimentin
chr12_+_53440753 0.33 ENST00000379902.3
tensin like C1 domain containing phosphatase (tensin 2)
chr6_-_46703069 0.33 ENST00000538237.1
ENST00000274793.7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr18_-_21242833 0.32 ENST00000586087.1
ENST00000592179.1
ankyrin repeat domain 29
chr16_-_79633799 0.32 ENST00000569649.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr1_+_205473720 0.32 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
cyclin-dependent kinase 18
chr3_-_197024394 0.32 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
discs, large homolog 1 (Drosophila)
chr12_-_45270077 0.32 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NEL-like 2 (chicken)
chr4_+_4388805 0.32 ENST00000504171.1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr19_-_17559376 0.32 ENST00000341130.5
transmembrane protein 221
chr12_-_6756559 0.32 ENST00000536350.1
ENST00000414226.2
ENST00000546114.1
acrosin binding protein
chr2_-_27718052 0.32 ENST00000264703.3
fibronectin type III domain containing 4
chr6_+_43543942 0.31 ENST00000372226.1
ENST00000443535.1
polymerase (DNA directed), eta
chr10_-_104001231 0.31 ENST00000370002.3
paired-like homeodomain 3
chr12_-_122238464 0.31 ENST00000546227.1
ras homolog family member F (in filopodia)
chr19_-_41859814 0.31 ENST00000221930.5
transforming growth factor, beta 1
chr22_+_50609150 0.31 ENST00000159647.5
ENST00000395842.2
pannexin 2
chr7_+_128577972 0.31 ENST00000357234.5
ENST00000477535.1
ENST00000479582.1
ENST00000464557.1
ENST00000402030.2
interferon regulatory factor 5
chr13_-_49107303 0.30 ENST00000344532.3
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chrX_-_107019181 0.30 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22 domain family, member 3
chr9_+_78505581 0.30 ENST00000376767.3
ENST00000376752.4
proprotein convertase subtilisin/kexin type 5
chrX_-_107018969 0.30 ENST00000372383.4
TSC22 domain family, member 3
chr6_+_43543864 0.30 ENST00000372236.4
ENST00000535400.1
polymerase (DNA directed), eta
chr6_-_166401527 0.30 ENST00000455853.1
ENST00000584911.1
long intergenic non-protein coding RNA 473
chr19_-_5340730 0.30 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
protein tyrosine phosphatase, receptor type, S
chr8_+_144349606 0.29 ENST00000521682.1
ENST00000340042.1
GLI family zinc finger 4
chr12_+_1929783 0.29 ENST00000535041.1
leucine-rich repeats and transmembrane domains 2
chr4_+_150999418 0.29 ENST00000296550.7
doublecortin-like kinase 2
chr19_-_49140609 0.29 ENST00000601104.1
D site of albumin promoter (albumin D-box) binding protein
chr8_-_144651024 0.29 ENST00000524906.1
ENST00000532862.1
ENST00000534459.1
maestro heat-like repeat family member 6
chr16_-_31439735 0.29 ENST00000287490.4
cytochrome c oxidase subunit VIa polypeptide 2
chr12_+_1929421 0.29 ENST00000543818.1
leucine-rich repeats and transmembrane domains 2
chr17_+_79373540 0.29 ENST00000307745.7
BAH and coiled-coil domain-containing protein 1
chr2_+_7057523 0.28 ENST00000320892.6
ring finger protein 144A
chr7_+_4721885 0.28 ENST00000328914.4
forkhead box K1
chr3_-_127541679 0.28 ENST00000265052.5
monoglyceride lipase
chr12_+_1929644 0.28 ENST00000299194.1
leucine-rich repeats and transmembrane domains 2
chr14_-_53162361 0.28 ENST00000395686.3
ERO1-like (S. cerevisiae)
chr11_+_126225789 0.28 ENST00000530591.1
ENST00000534083.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr2_+_96012397 0.28 ENST00000468529.1
Kv channel interacting protein 3, calsenilin
chr4_+_4388245 0.28 ENST00000433139.2
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr21_+_46359907 0.28 ENST00000291634.6
ENST00000397826.3
ENST00000458015.1
family with sequence similarity 207, member A
chr16_+_2521500 0.28 ENST00000293973.1
netrin 3
chr16_-_79634595 0.28 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr11_+_94822968 0.27 ENST00000278505.4
endonuclease domain containing 1
chr2_+_120770645 0.27 ENST00000443902.2
erythrocyte membrane protein band 4.1 like 5
chr15_-_70388943 0.27 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr4_+_657485 0.27 ENST00000471824.2
phosphodiesterase 6B, cGMP-specific, rod, beta
chr20_-_62680984 0.27 ENST00000340356.7
SRY (sex determining region Y)-box 18
chr17_+_40440481 0.27 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
signal transducer and activator of transcription 5A
chr1_-_62785054 0.27 ENST00000371153.4
KN motif and ankyrin repeat domains 4
chr8_-_125740514 0.27 ENST00000325064.5
ENST00000518547.1
metastasis suppressor 1
chr8_-_142011316 0.27 ENST00000522684.1
ENST00000395218.2
ENST00000524357.1
ENST00000521332.1
ENST00000524040.1
ENST00000519881.1
ENST00000520045.1
protein tyrosine kinase 2
chr14_+_21152706 0.27 ENST00000397995.2
ENST00000304704.4
ENST00000553909.1
ribonuclease, RNase A family, 4
Homo sapiens ribonuclease, RNase A family, 4 (RNASE4), transcript variant 4, mRNA.
chr11_+_64059464 0.27 ENST00000394525.2
potassium channel, subfamily K, member 4
chr17_+_73084038 0.26 ENST00000578376.1
ENST00000329783.4
solute carrier family 16 (monocarboxylate transporter), member 5
chr10_-_121302195 0.26 ENST00000369103.2
regulator of G-protein signaling 10
chr12_+_128751948 0.26 ENST00000435159.2
transmembrane protein 132C
chrX_-_153363125 0.26 ENST00000407218.1
ENST00000453960.2
methyl CpG binding protein 2 (Rett syndrome)
chr16_+_67700673 0.26 ENST00000403458.4
ENST00000602365.1
chromosome 16 open reading frame 86
chr19_+_42746927 0.26 ENST00000378108.1
AC006486.1
chr6_+_147830063 0.26 ENST00000367474.1
sterile alpha motif domain containing 5
chr17_-_64187973 0.26 ENST00000583358.1
ENST00000392769.2
centrosomal protein 112kDa
chr1_-_241520525 0.26 ENST00000366565.1
regulator of G-protein signaling 7
chr6_-_105584560 0.26 ENST00000336775.5
blood vessel epicardial substance
chr12_+_70760056 0.26 ENST00000258111.4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr1_+_109792641 0.26 ENST00000271332.3
cadherin, EGF LAG seven-pass G-type receptor 2
chr2_+_204193149 0.26 ENST00000422511.2
abl-interactor 2
chr4_-_8442438 0.25 ENST00000356406.5
ENST00000413009.2
acyl-CoA oxidase 3, pristanoyl
chr16_-_755726 0.25 ENST00000324361.5
F-box and leucine-rich repeat protein 16
chr4_-_57522598 0.25 ENST00000553379.2
HOP homeobox
chr2_-_177502659 0.25 ENST00000295549.4
long intergenic non-protein coding RNA 1116
chr17_+_73083816 0.25 ENST00000580123.1
ENST00000578847.1
solute carrier family 16 (monocarboxylate transporter), member 5
chr4_-_57522673 0.25 ENST00000381255.3
ENST00000317745.7
ENST00000555760.2
ENST00000556614.2
HOP homeobox
chr18_+_43913919 0.25 ENST00000587853.1
ring finger protein 165
chr4_+_4387983 0.25 ENST00000397958.1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr1_+_150521876 0.25 ENST00000369041.5
ENST00000271643.4
ENST00000538795.1
ADAMTS-like 4
Protein LOC100996516
chr1_-_111217603 0.25 ENST00000369769.2
potassium voltage-gated channel, shaker-related subfamily, member 3
chr22_-_19137796 0.25 ENST00000086933.2
goosecoid homeobox 2
chr9_-_101471479 0.25 ENST00000259455.2
gamma-aminobutyric acid (GABA) B receptor, 2
chr4_-_57522470 0.25 ENST00000503639.3
HOP homeobox
chr12_-_6756609 0.25 ENST00000229243.2
acrosin binding protein
chr18_+_72265084 0.25 ENST00000582337.1
zinc finger protein 407
chr22_+_33197683 0.25 ENST00000266085.6
TIMP metallopeptidase inhibitor 3
chr19_-_38746979 0.25 ENST00000591291.1
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr20_+_57430162 0.25 ENST00000450130.1
ENST00000349036.3
ENST00000423897.1
GNAS complex locus
chr6_-_105627735 0.24 ENST00000254765.3
popeye domain containing 3
chr5_-_524445 0.24 ENST00000514375.1
ENST00000264938.3
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
chr4_+_183370146 0.24 ENST00000510504.1
teneurin transmembrane protein 3
chr7_-_140624499 0.24 ENST00000288602.6
v-raf murine sarcoma viral oncogene homolog B
chr11_-_6677018 0.24 ENST00000299441.3
dachsous cadherin-related 1
chr2_-_107503558 0.24 ENST00000361686.4
ENST00000409087.3
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
chr3_+_190231891 0.24 ENST00000434491.1
ENST00000422940.1
ENST00000317757.3
interleukin 1 receptor accessory protein
chr5_-_171881362 0.24 ENST00000519643.1
SH3 and PX domains 2B
chr4_+_2965307 0.24 ENST00000398051.4
ENST00000503518.2
ENST00000398052.4
ENST00000345167.6
ENST00000504933.1
ENST00000442472.2
G protein-coupled receptor kinase 4
chr8_-_22014255 0.24 ENST00000424267.2
leucine-rich repeat LGI family, member 3
chr15_+_68871308 0.24 ENST00000261861.5
coronin, actin binding protein, 2B
chr6_-_2876744 0.24 ENST00000420981.2
RP11-420G6.4
chr12_-_95044309 0.23 ENST00000261226.4
transmembrane and coiled-coil domain family 3
chr5_-_172662303 0.23 ENST00000517440.1
ENST00000329198.4
NK2 homeobox 5
chr3_+_134204551 0.23 ENST00000332047.5
ENST00000354446.3
centrosomal protein 63kDa
chr2_+_204193129 0.23 ENST00000417864.1
abl-interactor 2
chr17_+_79989500 0.23 ENST00000306897.4
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr7_-_149470540 0.23 ENST00000302017.3
zinc finger protein 467
chr19_-_51143075 0.23 ENST00000600079.1
ENST00000593901.1
synaptotagmin III
chr1_+_153651078 0.23 ENST00000368680.3
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr6_+_292051 0.23 ENST00000344450.5
dual specificity phosphatase 22
chr4_-_16228083 0.23 ENST00000399920.3
transmembrane anterior posterior transformation 1
chr15_-_55700216 0.23 ENST00000569205.1
cell cycle progression 1
chrX_-_153151586 0.23 ENST00000370060.1
ENST00000370055.1
ENST00000420165.1
L1 cell adhesion molecule
chrX_+_153686614 0.22 ENST00000369682.3
plexin A3
chr3_+_134204881 0.22 ENST00000511574.1
ENST00000337090.3
ENST00000383229.3
centrosomal protein 63kDa
chr6_+_168841817 0.22 ENST00000356284.2
ENST00000354536.5
SPARC related modular calcium binding 2
chr1_-_11865982 0.22 ENST00000418034.1
methylenetetrahydrofolate reductase (NAD(P)H)
chr20_+_61569463 0.22 ENST00000266069.3
GID complex subunit 8
chr1_+_66258846 0.22 ENST00000341517.4
phosphodiesterase 4B, cAMP-specific
chr10_-_121296045 0.22 ENST00000392865.1
regulator of G-protein signaling 10
chr19_-_5567996 0.22 ENST00000448587.1
tissue differentiation-inducing non-protein coding RNA
chr6_+_56819895 0.22 ENST00000370748.3
BEN domain containing 6
chr6_+_139456226 0.22 ENST00000367658.2
headcase homolog (Drosophila)
chr19_-_55954230 0.22 ENST00000376325.4
shisa family member 7
chr6_-_46703430 0.22 ENST00000537365.1
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

Network of associatons between targets according to the STRING database.

First level regulatory network of HIC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 0.7 GO:0032811 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.2 0.3 GO:0071810 regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.2 0.8 GO:0032455 nerve growth factor processing(GO:0032455)
0.2 0.2 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.2 0.5 GO:0045062 extrathymic T cell selection(GO:0045062)
0.2 1.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 1.0 GO:0060992 response to fungicide(GO:0060992)
0.1 0.4 GO:0009405 pathogenesis(GO:0009405)
0.1 0.4 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 0.4 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.1 0.5 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.4 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.2 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.4 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.6 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.1 0.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.5 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1 0.3 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.1 0.1 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.1 0.3 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.8 GO:0060179 male mating behavior(GO:0060179)
0.1 0.4 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.3 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.3 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.1 0.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.4 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.3 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.3 GO:0035623 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.1 0.4 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 1.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.3 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.2 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.1 GO:0097102 endothelial tip cell fate specification(GO:0097102)
0.1 0.4 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.1 0.5 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.2 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.7 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.6 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.5 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.1 0.2 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.4 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.4 GO:0030035 microspike assembly(GO:0030035)
0.1 0.2 GO:1904106 protein localization to microvillus(GO:1904106)
0.1 0.5 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.2 GO:0042700 luteinizing hormone signaling pathway(GO:0042700) cellular response to luteinizing hormone stimulus(GO:0071373)
0.1 0.5 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.1 0.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.1 0.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.8 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.1 0.2 GO:0060926 cardiac pacemaker cell development(GO:0060926) sinoatrial node cell development(GO:0060931)
0.1 0.3 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.2 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.1 0.1 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.1 0.1 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.1 0.3 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.7 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.7 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.2 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.2 GO:0009447 putrescine catabolic process(GO:0009447)
0.1 0.2 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.1 0.2 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.1 0.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.4 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.4 GO:0046836 glycolipid transport(GO:0046836)
0.1 0.2 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.5 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.4 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.0 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:1903971 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 0.1 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.4 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.1 GO:0043605 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.0 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.3 GO:0060214 endocardium formation(GO:0060214)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.2 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.4 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.2 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.1 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.5 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.5 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.0 GO:0060458 right lung development(GO:0060458)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.1 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.0 0.2 GO:0097021 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.1 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.0 0.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.2 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:1900369 transcription, RNA-templated(GO:0001172) negative regulation of RNA interference(GO:1900369)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.2 GO:0090309 maintenance of DNA methylation(GO:0010216) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.3 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0046222 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.2 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0010957 negative regulation of vitamin D biosynthetic process(GO:0010957)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187)
0.0 0.1 GO:2000170 negative regulation of gap junction assembly(GO:1903597) positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.0 0.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.7 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.1 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.6 GO:0009650 UV protection(GO:0009650)
0.0 0.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:0072240 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.0 0.1 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798) frontal suture morphogenesis(GO:0060364)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.1 GO:1905123 regulation of glucosylceramidase activity(GO:1905123)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 0.1 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0042756 drinking behavior(GO:0042756)
0.0 0.1 GO:0006090 pyruvate metabolic process(GO:0006090)
0.0 0.2 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.0 0.2 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.3 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.2 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.7 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 0.6 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0003160 endocardium morphogenesis(GO:0003160)
0.0 0.1 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.0 0.3 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.0 0.2 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.7 GO:0097503 sialylation(GO:0097503)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.2 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412) regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.2 GO:0051931 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.3 GO:0014041 regulation of neuron maturation(GO:0014041)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.6 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.2 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0072205 metanephric collecting duct development(GO:0072205)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0060022 hard palate development(GO:0060022)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0035768 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.4 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.0 0.0 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.6 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.3 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860)
0.0 0.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.0 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.2 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.4 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0060995 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.0 0.3 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.0 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.0 GO:0007215 glutamate receptor signaling pathway(GO:0007215)
0.0 0.1 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.1 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.0 GO:1904204 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.1 GO:0019363 nicotinamide nucleotide biosynthetic process(GO:0019359) pyridine nucleotide biosynthetic process(GO:0019363)
0.0 0.0 GO:0019322 pentose biosynthetic process(GO:0019322)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0 0.0 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.0 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.0 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.1 GO:0098868 endochondral bone growth(GO:0003416) bone growth(GO:0098868)
0.0 0.4 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0002934 desmosome organization(GO:0002934)
0.0 0.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.1 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.3 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.3 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.0 GO:0010157 response to chlorate(GO:0010157)
0.0 0.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.4 GO:0030201 heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0 0.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.3 GO:0002931 response to ischemia(GO:0002931)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.0 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634) positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.9 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0046108 uridine metabolic process(GO:0046108)
0.0 0.0 GO:0030578 PML body organization(GO:0030578)
0.0 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.4 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.0 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.0 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.5 GO:0001706 endoderm formation(GO:0001706)
0.0 0.0 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.0 GO:0014063 regulation of serotonin secretion(GO:0014062) negative regulation of serotonin secretion(GO:0014063)
0.0 0.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0060872 semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0 0.0 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.0 GO:0002678 chronic inflammatory response to non-antigenic stimulus(GO:0002545) positive regulation of chronic inflammatory response(GO:0002678) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.0 0.0 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.0 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.0 GO:2001226 negative regulation of chloride transport(GO:2001226)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.6 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.5 GO:0031251 PAN complex(GO:0031251)
0.1 0.1 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 1.1 GO:0070852 cell body fiber(GO:0070852)
0.1 0.3 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.8 GO:0098845 postsynaptic endosome(GO:0098845)
0.1 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.3 GO:0045160 myosin I complex(GO:0045160)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 0.4 GO:0032437 cuticular plate(GO:0032437)
0.1 0.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.9 GO:0032059 muscle thin filament tropomyosin(GO:0005862) bleb(GO:0032059)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.6 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.1 GO:1903349 omegasome membrane(GO:1903349)
0.0 0.3 GO:0043219 lateral loop(GO:0043219)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.9 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.0 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.0 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 2.2 GO:0034705 potassium channel complex(GO:0034705)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.4 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.7 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.0 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.3 1.1 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 0.7 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 0.7 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 0.5 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 1.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.4 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 1.0 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.3 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.4 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.3 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.5 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.4 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.4 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.1 0.7 GO:0043426 MRF binding(GO:0043426)
0.1 0.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 0.5 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.7 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.3 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.1 0.3 GO:0002054 nucleobase binding(GO:0002054)
0.1 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.5 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.2 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 0.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.3 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 0.2 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.4 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.2 GO:0070364 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 2.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.2 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.2 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.3 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.2 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.3 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.5 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.2 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.3 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.6 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.5 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.1 GO:0042954 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.0 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.3 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.0 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0005542 folic acid binding(GO:0005542)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.0 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 2.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.1 ST ADRENERGIC Adrenergic Pathway
0.0 0.4 PID ENDOTHELIN PATHWAY Endothelins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.7 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 2.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.5 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 1.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.7 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME SIGNALLING BY NGF Genes involved in Signalling by NGF
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10