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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HIF1A

Z-value: 0.82

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Transcription factors associated with HIF1A

Gene Symbol Gene ID Gene Info
HIF1A
ENSG00000100644.12 hypoxia inducible factor 1 subunit alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIF1Ahg19_v2_chr14_+_62162258_62162269-0.451.2e-02Click!

Activity profile of HIF1A motif

Sorted Z-values of HIF1A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_19988462 3.69 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr5_+_10441970 2.10 ENST00000274134.4
ROPN1L
rhophilin associated tail protein 1-like
chr4_-_186317034 1.97 ENST00000505916.1
LRP2BP
LRP2 binding protein
chr1_+_150254936 1.89 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr8_+_75896731 1.73 ENST00000262207.4
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr7_+_48075108 1.67 ENST00000420324.1
ENST00000435376.1
ENST00000430738.1
ENST00000348904.3
ENST00000539619.1
C7orf57
chromosome 7 open reading frame 57
chr12_+_7023735 1.62 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
ENO2
enolase 2 (gamma, neuronal)
chr12_+_7023491 1.61 ENST00000541477.1
ENST00000229277.1
ENO2
enolase 2 (gamma, neuronal)
chr2_-_28113965 1.54 ENST00000302188.3
RBKS
ribokinase
chr2_-_220083076 1.25 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr2_-_28113217 1.24 ENST00000444339.2
RBKS
ribokinase
chr11_+_74204395 1.19 ENST00000526036.1
AP001372.2
AP001372.2
chr3_-_145878954 1.18 ENST00000282903.5
ENST00000360060.3
PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr19_+_5720666 1.15 ENST00000381624.3
ENST00000381614.2
CATSPERD
catsper channel auxiliary subunit delta
chr8_+_17354617 1.11 ENST00000470360.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr10_+_120789223 1.08 ENST00000425699.1
NANOS1
nanos homolog 1 (Drosophila)
chr19_-_55691614 1.06 ENST00000592470.1
ENST00000354308.3
SYT5
synaptotagmin V
chrX_+_69509927 0.99 ENST00000374403.3
KIF4A
kinesin family member 4A
chr8_+_17354587 0.96 ENST00000494857.1
ENST00000522656.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr14_-_64970494 0.93 ENST00000608382.1
ZBTB25
zinc finger and BTB domain containing 25
chr1_+_214454492 0.90 ENST00000366957.5
ENST00000415093.2
SMYD2
SET and MYND domain containing 2
chr10_-_93392811 0.87 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr2_+_173420697 0.85 ENST00000282077.3
ENST00000392571.2
ENST00000410055.1
PDK1
pyruvate dehydrogenase kinase, isozyme 1
chr2_-_216946500 0.84 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr4_-_39529049 0.80 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
UGDH
UDP-glucose 6-dehydrogenase
chr11_-_76155700 0.79 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr17_-_34890759 0.78 ENST00000431794.3
MYO19
myosin XIX
chr5_-_146889619 0.77 ENST00000343218.5
DPYSL3
dihydropyrimidinase-like 3
chr4_-_39529180 0.77 ENST00000515021.1
ENST00000510490.1
ENST00000316423.6
UGDH
UDP-glucose 6-dehydrogenase
chr12_-_49318715 0.76 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr2_-_68384603 0.75 ENST00000406245.2
ENST00000409164.1
ENST00000295121.6
WDR92
WD repeat domain 92
chr3_+_113666748 0.74 ENST00000330212.3
ENST00000498275.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr11_+_7534999 0.72 ENST00000528947.1
ENST00000299492.4
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_+_129732467 0.71 ENST00000413543.2
PHF17
jade family PHD finger 1
chr22_+_41777927 0.67 ENST00000266304.4
TEF
thyrotrophic embryonic factor
chr2_-_220083671 0.66 ENST00000439002.2
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr18_+_43913919 0.65 ENST00000587853.1
RNF165
ring finger protein 165
chr2_-_220083692 0.65 ENST00000265316.3
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr22_-_24181174 0.64 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3
derlin 3
chr11_-_76155618 0.63 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chrX_-_13956737 0.63 ENST00000454189.2
GPM6B
glycoprotein M6B
chr3_+_100211412 0.61 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
TMEM45A
transmembrane protein 45A
chr8_+_26240414 0.60 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr13_-_24463530 0.58 ENST00000382172.3
MIPEP
mitochondrial intermediate peptidase
chr6_+_35265586 0.56 ENST00000542066.1
ENST00000316637.5
DEF6
differentially expressed in FDCP 6 homolog (mouse)
chrX_-_34675391 0.56 ENST00000275954.3
TMEM47
transmembrane protein 47
chr11_-_118901559 0.55 ENST00000330775.7
ENST00000545985.1
ENST00000357590.5
ENST00000538950.1
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr1_+_100436065 0.55 ENST00000370153.1
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr7_+_128095945 0.54 ENST00000257696.4
HILPDA
hypoxia inducible lipid droplet-associated
chr6_-_83775489 0.54 ENST00000369747.3
UBE3D
ubiquitin protein ligase E3D
chr16_-_30022735 0.54 ENST00000564944.1
DOC2A
double C2-like domains, alpha
chr2_+_27665232 0.53 ENST00000543753.1
ENST00000288873.3
KRTCAP3
keratinocyte associated protein 3
chr12_+_110906169 0.52 ENST00000377673.5
FAM216A
family with sequence similarity 216, member A
chr15_-_60884706 0.49 ENST00000449337.2
RORA
RAR-related orphan receptor A
chr20_+_30946106 0.49 ENST00000375687.4
ENST00000542461.1
ASXL1
additional sex combs like 1 (Drosophila)
chr4_-_104119528 0.49 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE
centromere protein E, 312kDa
chr1_-_231376836 0.49 ENST00000451322.1
C1orf131
chromosome 1 open reading frame 131
chr19_-_1568057 0.48 ENST00000402693.4
ENST00000388824.6
MEX3D
mex-3 RNA binding family member D
chr17_+_7608511 0.48 ENST00000226091.2
EFNB3
ephrin-B3
chr2_+_27665289 0.48 ENST00000407293.1
KRTCAP3
keratinocyte associated protein 3
chr14_+_64970662 0.48 ENST00000556965.1
ENST00000554015.1
ZBTB1
zinc finger and BTB domain containing 1
chrX_-_13956497 0.46 ENST00000398361.3
GPM6B
glycoprotein M6B
chr11_-_76381781 0.46 ENST00000260061.5
ENST00000404995.1
LRRC32
leucine rich repeat containing 32
chrX_+_77359671 0.45 ENST00000373316.4
PGK1
phosphoglycerate kinase 1
chr9_-_139922726 0.45 ENST00000265662.5
ENST00000371605.3
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr15_+_41056218 0.45 ENST00000260447.4
GCHFR
GTP cyclohydrolase I feedback regulator
chr2_+_10183651 0.44 ENST00000305883.1
KLF11
Kruppel-like factor 11
chr7_+_116593433 0.44 ENST00000323984.3
ENST00000393449.1
ST7
suppression of tumorigenicity 7
chr19_-_49137790 0.44 ENST00000599385.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr19_-_49137762 0.43 ENST00000593500.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr6_+_151561085 0.43 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr15_+_41056255 0.43 ENST00000561160.1
ENST00000559445.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr1_-_92351769 0.42 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr1_-_159894319 0.42 ENST00000320307.4
TAGLN2
transgelin 2
chr11_-_17498348 0.42 ENST00000389817.3
ENST00000302539.4
ABCC8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr16_-_30022293 0.41 ENST00000565273.1
ENST00000567332.2
ENST00000350119.4
DOC2A
double C2-like domains, alpha
chr2_-_97652324 0.41 ENST00000490605.2
FAM178B
family with sequence similarity 178, member B
chrX_+_77359726 0.41 ENST00000442431.1
PGK1
phosphoglycerate kinase 1
chr7_+_26331541 0.40 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10
sorting nexin 10
chr3_+_49044798 0.40 ENST00000438660.1
ENST00000608424.1
ENST00000415265.2
WDR6
WD repeat domain 6
chr6_-_153304148 0.40 ENST00000229758.3
FBXO5
F-box protein 5
chr7_+_128095900 0.40 ENST00000435296.2
HILPDA
hypoxia inducible lipid droplet-associated
chr17_-_57184260 0.39 ENST00000376149.3
ENST00000393066.3
TRIM37
tripartite motif containing 37
chr11_+_9595180 0.39 ENST00000450114.2
WEE1
WEE1 G2 checkpoint kinase
chr2_-_97652290 0.39 ENST00000327896.3
FAM178B
family with sequence similarity 178, member B
chr16_+_66878814 0.39 ENST00000394069.3
CA7
carbonic anhydrase VII
chr8_-_103425047 0.38 ENST00000520539.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr2_+_216946589 0.38 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
TMEM169
transmembrane protein 169
chr1_-_26233423 0.37 ENST00000357865.2
STMN1
stathmin 1
chr16_-_54963026 0.37 ENST00000560208.1
ENST00000557792.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr6_+_87865262 0.37 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr19_+_41903709 0.37 ENST00000542943.1
ENST00000457836.2
BCKDHA
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr14_-_24685246 0.36 ENST00000396833.2
ENST00000288087.7
MDP1
magnesium-dependent phosphatase 1
chr1_+_22333943 0.36 ENST00000400271.2
CELA3A
chymotrypsin-like elastase family, member 3A
chr17_+_80416050 0.36 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
NARF
nuclear prelamin A recognition factor
chr17_-_73127353 0.36 ENST00000580423.1
ENST00000578337.1
ENST00000582160.1
NT5C
5', 3'-nucleotidase, cytosolic
chr11_+_73498898 0.36 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48
mitochondrial ribosomal protein L48
chr12_-_121734489 0.36 ENST00000412367.2
ENST00000402834.4
ENST00000404169.3
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr17_-_73127826 0.36 ENST00000582170.1
ENST00000245552.2
NT5C
5', 3'-nucleotidase, cytosolic
chr3_+_25831567 0.35 ENST00000280701.3
ENST00000420173.2
OXSM
3-oxoacyl-ACP synthase, mitochondrial
chr13_+_27998681 0.35 ENST00000381140.4
GTF3A
general transcription factor IIIA
chr17_+_76311791 0.35 ENST00000586321.1
AC061992.2
AC061992.2
chr11_-_63933504 0.34 ENST00000255681.6
MACROD1
MACRO domain containing 1
chr8_-_95908902 0.34 ENST00000520509.1
CCNE2
cyclin E2
chr11_+_6625046 0.33 ENST00000396751.2
ILK
integrin-linked kinase
chr10_+_49514698 0.33 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr9_-_139922631 0.33 ENST00000341511.6
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr11_+_6624955 0.33 ENST00000299421.4
ENST00000537806.1
ILK
integrin-linked kinase
chr2_+_88991162 0.33 ENST00000283646.4
RPIA
ribose 5-phosphate isomerase A
chr2_+_32288657 0.32 ENST00000345662.1
SPAST
spastin
chr5_+_126112794 0.32 ENST00000261366.5
ENST00000395354.1
LMNB1
lamin B1
chr13_+_103451399 0.32 ENST00000257336.1
ENST00000448849.2
BIVM
basic, immunoglobulin-like variable motif containing
chr3_-_71834318 0.32 ENST00000353065.3
PROK2
prokineticin 2
chr3_+_63898275 0.31 ENST00000538065.1
ATXN7
ataxin 7
chr11_+_6624970 0.31 ENST00000420936.2
ENST00000528995.1
ILK
integrin-linked kinase
chr2_+_32288725 0.31 ENST00000315285.3
SPAST
spastin
chr4_+_17578815 0.31 ENST00000226299.4
LAP3
leucine aminopeptidase 3
chr11_-_18343669 0.30 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
HPS5
Hermansky-Pudlak syndrome 5
chr13_+_115079949 0.30 ENST00000361283.1
CHAMP1
chromosome alignment maintaining phosphoprotein 1
chr17_+_6918354 0.30 ENST00000552775.1
C17orf49
chromosome 17 open reading frame 49
chr4_-_54930790 0.29 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr6_+_89791507 0.28 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr6_-_159240415 0.28 ENST00000367075.3
EZR
ezrin
chr5_-_131563501 0.28 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr3_-_81811312 0.27 ENST00000429644.2
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr17_-_67323305 0.27 ENST00000392677.2
ENST00000593153.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr14_-_23770683 0.27 ENST00000561437.1
ENST00000559942.1
ENST00000560913.1
ENST00000559314.1
ENST00000558058.1
PPP1R3E
protein phosphatase 1, regulatory subunit 3E
chr17_-_67323232 0.27 ENST00000592568.1
ENST00000392676.3
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr12_+_28343365 0.27 ENST00000545336.1
CCDC91
coiled-coil domain containing 91
chr22_-_31742218 0.27 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr19_-_5719860 0.27 ENST00000590729.1
LONP1
lon peptidase 1, mitochondrial
chr2_+_26915584 0.27 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr4_-_17783135 0.26 ENST00000265018.3
FAM184B
family with sequence similarity 184, member B
chr4_+_37245799 0.26 ENST00000309447.5
KIAA1239
KIAA1239
chr9_+_115983808 0.26 ENST00000374210.6
ENST00000374212.4
SLC31A1
solute carrier family 31 (copper transporter), member 1
chr17_-_35969409 0.26 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG
synergin, gamma
chr1_+_28052518 0.26 ENST00000530324.1
ENST00000234549.7
ENST00000373949.1
ENST00000010299.6
FAM76A
family with sequence similarity 76, member A
chr22_+_19701985 0.26 ENST00000455784.2
ENST00000406395.1
SEPT5
septin 5
chr3_-_71632894 0.26 ENST00000493089.1
FOXP1
forkhead box P1
chr12_+_54332535 0.25 ENST00000243056.3
HOXC13
homeobox C13
chr11_-_62414070 0.25 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
GANAB
glucosidase, alpha; neutral AB
chr20_+_33464238 0.25 ENST00000360596.2
ACSS2
acyl-CoA synthetase short-chain family member 2
chr7_+_96747030 0.25 ENST00000360382.4
ACN9
ACN9 homolog (S. cerevisiae)
chr17_+_80416482 0.25 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
NARF
nuclear prelamin A recognition factor
chr2_+_204192942 0.25 ENST00000295851.5
ENST00000261017.5
ABI2
abl-interactor 2
chr6_-_153304697 0.25 ENST00000367241.3
FBXO5
F-box protein 5
chr15_+_38544476 0.25 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr9_+_117373486 0.25 ENST00000288502.4
ENST00000374049.4
C9orf91
chromosome 9 open reading frame 91
chrX_+_24483338 0.24 ENST00000379162.4
ENST00000441463.2
PDK3
pyruvate dehydrogenase kinase, isozyme 3
chr7_+_43152191 0.24 ENST00000395891.2
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr1_-_109506036 0.24 ENST00000369976.1
ENST00000356970.2
ENST00000369971.2
ENST00000415331.1
ENST00000357393.4
CLCC1
AKNAD1
chloride channel CLIC-like 1
AKNA domain containing 1
chr5_+_49962772 0.24 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr7_-_100026280 0.24 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr15_-_59665062 0.24 ENST00000288235.4
MYO1E
myosin IE
chr12_+_28343353 0.24 ENST00000539107.1
CCDC91
coiled-coil domain containing 91
chr12_-_2113583 0.23 ENST00000397173.4
ENST00000280665.6
DCP1B
decapping mRNA 1B
chr20_+_33464407 0.23 ENST00000253382.5
ACSS2
acyl-CoA synthetase short-chain family member 2
chr16_+_66914264 0.23 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr17_+_57642886 0.23 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DHX40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr14_-_20923195 0.23 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr17_+_72428218 0.23 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr7_-_139876812 0.22 ENST00000397560.2
JHDM1D
lysine (K)-specific demethylase 7A
chr21_+_45719921 0.22 ENST00000349048.4
PFKL
phosphofructokinase, liver
chr17_-_42908155 0.22 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1
gap junction protein, gamma 1, 45kDa
chr22_-_31741757 0.22 ENST00000215919.3
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr17_+_66287628 0.21 ENST00000581639.1
ENST00000452479.2
ARSG
arylsulfatase G
chr12_-_15374343 0.21 ENST00000256953.2
ENST00000546331.1
RERG
RAS-like, estrogen-regulated, growth inhibitor
chr12_+_6977258 0.21 ENST00000488464.2
ENST00000535434.1
ENST00000493987.1
TPI1
triosephosphate isomerase 1
chr8_-_103424916 0.21 ENST00000220959.4
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr9_-_115983568 0.21 ENST00000446284.1
ENST00000414250.1
FKBP15
FK506 binding protein 15, 133kDa
chr14_-_77495007 0.20 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr9_-_115983641 0.20 ENST00000238256.3
FKBP15
FK506 binding protein 15, 133kDa
chr19_+_18530146 0.20 ENST00000348495.6
ENST00000270061.7
SSBP4
single stranded DNA binding protein 4
chr16_+_29467127 0.20 ENST00000344620.6
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr1_-_51425772 0.19 ENST00000371778.4
FAF1
Fas (TNFRSF6) associated factor 1
chr12_-_64616019 0.19 ENST00000311915.8
ENST00000398055.3
ENST00000544871.1
C12orf66
chromosome 12 open reading frame 66
chr2_+_232575128 0.19 ENST00000412128.1
PTMA
prothymosin, alpha
chr8_+_28351707 0.19 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3
frizzled family receptor 3
chr3_-_160823158 0.19 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr17_-_2206801 0.18 ENST00000544865.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr19_+_1407517 0.18 ENST00000336761.6
ENST00000233078.4
DAZAP1
DAZ associated protein 1
chr8_-_97273807 0.18 ENST00000517720.1
ENST00000287025.3
ENST00000523821.1
MTERFD1
MTERF domain containing 1
chr13_+_103451548 0.18 ENST00000419638.1
BIVM
basic, immunoglobulin-like variable motif containing
chr14_-_39901618 0.17 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr7_-_127032363 0.17 ENST00000393312.1
ZNF800
zinc finger protein 800
chr15_-_43622736 0.17 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
LCMT2
leucine carboxyl methyltransferase 2
chr1_-_43833628 0.17 ENST00000413844.2
ENST00000372458.3
ELOVL1
ELOVL fatty acid elongase 1
chr19_+_50180507 0.17 ENST00000454376.2
ENST00000524771.1
PRMT1
protein arginine methyltransferase 1
chr8_+_109455845 0.17 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chrX_+_105969893 0.17 ENST00000255499.2
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr8_+_98656336 0.17 ENST00000336273.3
MTDH
metadherin
chr11_-_65548265 0.16 ENST00000532090.2
AP5B1
adaptor-related protein complex 5, beta 1 subunit
chr4_+_4291924 0.16 ENST00000355834.3
ENST00000337872.4
ENST00000538529.1
ENST00000502918.1
ZBTB49
zinc finger and BTB domain containing 49
chr12_+_58013693 0.16 ENST00000320442.4
ENST00000379218.2
SLC26A10
solute carrier family 26, member 10
chr6_+_3259122 0.15 ENST00000438998.2
ENST00000380305.4
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr19_+_4472230 0.15 ENST00000301284.4
ENST00000586684.1
HDGFRP2
Hepatoma-derived growth factor-related protein 2
chr6_+_151561506 0.15 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr15_+_98503922 0.15 ENST00000268042.6
ARRDC4
arrestin domain containing 4
chr18_-_45457478 0.15 ENST00000402690.2
ENST00000356825.4
SMAD2
SMAD family member 2
chr8_-_103424986 0.15 ENST00000521922.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5

Network of associatons between targets according to the STRING database.

First level regulatory network of HIF1A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0034226 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.6 2.8 GO:0019303 D-ribose catabolic process(GO:0019303)
0.4 1.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3 0.3 GO:0006014 D-ribose metabolic process(GO:0006014)
0.3 0.9 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.3 1.6 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.2 0.9 GO:0035425 autocrine signaling(GO:0035425)
0.2 0.6 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.2 2.6 GO:0015886 heme transport(GO:0015886)
0.2 0.5 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.2 0.5 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 1.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.8 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.1 0.4 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.8 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.5 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.5 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 0.7 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.3 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 1.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.7 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.4 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.1 0.5 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.1 4.5 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.6 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.3 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.1 0.5 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 2.1 GO:0003351 epithelial cilium movement(GO:0003351)
0.1 0.6 GO:0034214 protein hexamerization(GO:0034214)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.4 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.2 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.1 0.8 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.6 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.2 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.1 1.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.1 0.2 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0060139 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0 0.3 GO:0072719 cellular response to cisplatin(GO:0072719)
0.0 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 1.7 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.5 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.9 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 1.0 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 1.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0006285 base-excision repair, AP site formation(GO:0006285) depurination(GO:0045007)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.8 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 2.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.4 GO:2001225 regulation of chloride transport(GO:2001225)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.3 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.3 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.5 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
0.0 0.3 GO:0043473 pigmentation(GO:0043473)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.5 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:2000051 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.8 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.2 GO:0072015 glomerular visceral epithelial cell development(GO:0072015)
0.0 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:1904764 clathrin coat disassembly(GO:0072318) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.3 GO:0051481 stabilization of membrane potential(GO:0030322) negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.0 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.4 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 3.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 0.8 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 1.1 GO:1990769 proximal neuron projection(GO:1990769)
0.1 1.1 GO:0036128 CatSper complex(GO:0036128)
0.1 0.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.9 GO:0005638 lamin filament(GO:0005638)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940) mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.8 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 1.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.4 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.5 2.1 GO:0005292 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.5 3.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 1.2 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.3 0.9 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.3 0.9 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.3 0.8 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.3 1.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.5 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.4 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.4 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.9 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.6 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 2.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 0.8 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.1 0.6 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.2 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.3 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.2 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 1.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.5 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 1.5 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.1 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 3.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.1 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism