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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HINFP1

Z-value: 0.51

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Transcription factors associated with HINFP1

Gene Symbol Gene ID Gene Info

Activity profile of HINFP1 motif

Sorted Z-values of HINFP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_154393260 1.53 ENST00000435029.4
kinesin family member 4B
chr2_-_234763147 1.44 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
Holliday junction recognition protein
chr9_-_94186131 1.34 ENST00000297689.3
nuclear factor, interleukin 3 regulated
chr18_+_12308046 1.28 ENST00000317702.5
tubulin, beta 6 class V
chr18_+_12308231 1.12 ENST00000590103.1
ENST00000591909.1
ENST00000586653.1
ENST00000592683.1
ENST00000590967.1
ENST00000591208.1
ENST00000591463.1
tubulin, beta 6 class V
chr10_-_75634219 1.05 ENST00000305762.7
calcium/calmodulin-dependent protein kinase II gamma
chr14_+_55033815 1.02 ENST00000554335.1
sterile alpha motif domain containing 4A
chr1_-_94147385 1.01 ENST00000260502.6
breast cancer anti-estrogen resistance 3
chr10_-_75634260 0.98 ENST00000372765.1
ENST00000351293.3
calcium/calmodulin-dependent protein kinase II gamma
chr16_+_57279248 0.89 ENST00000562023.1
ENST00000563234.1
ADP-ribosylation factor-like 2 binding protein
chr11_-_61659006 0.72 ENST00000278829.2
fatty acid desaturase 3
chr10_-_75634326 0.71 ENST00000322635.3
ENST00000444854.2
ENST00000423381.1
ENST00000322680.3
ENST00000394762.2
calcium/calmodulin-dependent protein kinase II gamma
chr2_-_130939115 0.71 ENST00000441135.1
ENST00000339679.7
ENST00000426662.2
ENST00000443958.2
ENST00000351288.6
ENST00000453750.1
ENST00000452225.2
sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
chr20_+_35974532 0.69 ENST00000373578.2
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr11_-_61658853 0.68 ENST00000525588.1
ENST00000540820.1
fatty acid desaturase 3
chr21_+_35445811 0.67 ENST00000399312.2
mitochondrial ribosomal protein S6
chr2_+_130939235 0.67 ENST00000425361.1
ENST00000457492.1
mitotic spindle organizing protein 2B
chr22_+_27053422 0.67 ENST00000413665.1
ENST00000421151.1
ENST00000456129.1
ENST00000430080.1
myocardial infarction associated transcript (non-protein coding)
chr21_+_35445827 0.66 ENST00000608209.1
ENST00000381151.3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr2_+_130939827 0.66 ENST00000409255.1
ENST00000455239.1
mitotic spindle organizing protein 2B
chr16_+_610407 0.65 ENST00000409413.3
chromosome 16 open reading frame 11
chr1_-_43232649 0.53 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
leucine proline-enriched proteoglycan (leprecan) 1
chr18_+_11981547 0.53 ENST00000588927.1
inositol(myo)-1(or 4)-monophosphatase 2
chr3_+_133292851 0.52 ENST00000503932.1
CDV3 homolog (mouse)
chr2_+_58655461 0.50 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
long intergenic non-protein coding RNA 1122
chr3_+_133293278 0.48 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3 homolog (mouse)
chrX_-_125686784 0.47 ENST00000371126.1
DDB1 and CUL4 associated factor 12-like 1
chr1_-_62784935 0.44 ENST00000354381.3
KN motif and ankyrin repeat domains 4
chr3_+_133292759 0.41 ENST00000431519.2
CDV3 homolog (mouse)
chr18_+_11981427 0.36 ENST00000269159.3
inositol(myo)-1(or 4)-monophosphatase 2
chr13_-_22033392 0.28 ENST00000320220.9
ENST00000415724.1
ENST00000422251.1
ENST00000382466.3
ENST00000542645.1
ENST00000400590.3
zinc finger, DHHC-type containing 20
chr10_+_72238517 0.27 ENST00000263563.6
phosphatase domain containing, paladin 1
chrX_-_119249819 0.26 ENST00000217999.2
Rhox homeobox family, member 1
chr15_+_85525205 0.24 ENST00000394553.1
ENST00000339708.5
phosphodiesterase 8A
chr19_-_14228541 0.21 ENST00000590853.1
ENST00000308677.4
protein kinase, cAMP-dependent, catalytic, alpha
chr1_+_222886694 0.21 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BRO1 domain and CAAX motif containing
chr1_-_62785054 0.19 ENST00000371153.4
KN motif and ankyrin repeat domains 4
chr19_-_5680499 0.19 ENST00000587589.1
chromosome 19 open reading frame 70
chr10_-_977564 0.19 ENST00000406525.2
La ribonucleoprotein domain family, member 4B
chr1_+_210111534 0.18 ENST00000422431.1
ENST00000534859.1
ENST00000399639.2
ENST00000537238.1
synaptotagmin XIV
chr6_-_144416737 0.17 ENST00000367569.2
splicing factor 3b, subunit 5, 10kDa
chr17_-_79481666 0.15 ENST00000575659.1
actin, gamma 1
chr14_+_73704201 0.14 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
papilin, proteoglycan-like sulfated glycoprotein
chr10_-_97453650 0.12 ENST00000371209.5
ENST00000371217.5
ENST00000430368.2
tectonic family member 3
chr7_+_6144514 0.05 ENST00000306177.5
ENST00000465073.2
ubiquitin specific peptidase 42
chr1_+_43232913 0.04 ENST00000372525.5
ENST00000536543.1
chromosome 1 open reading frame 50
chr1_+_42922173 0.02 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
phosphopantothenoylcysteine synthetase

Network of associatons between targets according to the STRING database.

First level regulatory network of HINFP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.9 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 2.7 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.1 0.7 GO:0015798 myo-inositol transport(GO:0015798)
0.1 1.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.4 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.0 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.9 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 1.3 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 1.4 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 1.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:1901621 cellular response to parathyroid hormone stimulus(GO:0071374) negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 2.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.7 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.2 0.9 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.7 GO:0071253 connexin binding(GO:0071253)
0.1 0.7 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.7 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 1.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.0 GO:0030371 translation repressor activity(GO:0030371)
0.0 2.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.7 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism